CN102210453A - Effervescent chewing gum and preparation method thereof - Google Patents

Effervescent chewing gum and preparation method thereof Download PDF

Info

Publication number
CN102210453A
CN102210453A CN2011101054518A CN201110105451A CN102210453A CN 102210453 A CN102210453 A CN 102210453A CN 2011101054518 A CN2011101054518 A CN 2011101054518A CN 201110105451 A CN201110105451 A CN 201110105451A CN 102210453 A CN102210453 A CN 102210453A
Authority
CN
China
Prior art keywords
chewing gum
effervesce
mass percent
extract
gum
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN2011101054518A
Other languages
Chinese (zh)
Inventor
李伟胜
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ZHUHAI SPECIAL ECONOMIC ZONE ERKANG PHARMACEUTICAL CO Ltd
Original Assignee
ZHUHAI SPECIAL ECONOMIC ZONE ERKANG PHARMACEUTICAL CO Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ZHUHAI SPECIAL ECONOMIC ZONE ERKANG PHARMACEUTICAL CO Ltd filed Critical ZHUHAI SPECIAL ECONOMIC ZONE ERKANG PHARMACEUTICAL CO Ltd
Priority to CN2011101054518A priority Critical patent/CN102210453A/en
Publication of CN102210453A publication Critical patent/CN102210453A/en
Pending legal-status Critical Current

Links

Landscapes

  • Confectionery (AREA)

Abstract

The invention changes the chewing gum use habit by utilizing a medicament quick-release preparation technology, and prevents residual gum base of the gum-based chewing gum from polluting the environment by changing the chewing gum through adding a disintegrating agent and other functional components. The effervescent chewing gum performs an acid-base reaction (effervescence) in a spittle environment to release mass bubbles, so that the components are slowly and automatically melt without chewing or turning by a tongue, the bubbles of effective components are dissolved to quickly moisturize effective components to play the functions of oral cavity cleaning, tooth protecting and other health-care functions; the effervescent chewing gum has a characteristic which cannot be incomparable with other types of chewing gum, namely the effervescent tablets make spittle acidic, which contributes to sufficient ionization of functional components, and helps absorption and utilization of the functional components without residues; and even the gum-based products are sufficiently chewed, partial components are still attached to the gum base, and spit to a garbage tank to cause environment pollution.

Description

Effervesce chewing gum and preparation method thereof
[technical field]
The present invention relates to a kind of chewing gum, be specifically related to a kind of effervesce chewing gum and preparation method thereof.
[background technology]
The traditional chewing gum that circulates on the present market, be by chewing or the candy of containing release function component type, raising along with people's living standard, variation has taken place in consumer's philosophy of life, oral care implement develops to diversification, multi-functional, new fashion direction from traditional product, and other oral care product is also developing rapidly.
Effervescent tablet is a kind of novel tablet of utilizing up-to-date medicine quick releasing formulation technological development to use in recent years, the difference of it and conventional tablet, just be that it also contains gas-producing disintegrant, after effervescent tablet is put into drinking-water, under the effect of gas-producing disintegrant, produce a large amount of bubbles (carbon dioxide) at once, make rapid disintegration of tablet and thawing, sometimes the bubble that disintegration produces also can make tablet roll up and down in water, quickens its disintegration and thawing.The carbon dioxide that produces during disintegration of tablet is partially dissolved in the drinking-water, making drinking-water that aesthetic feeling as the carbonated drink be arranged when drinking in the inlet.The effervescent tablet disintegration fast, taking convenience, onset be rapid, is specially adapted to children, the elderly and the patient of pill difficulty that swallows.Through the effervescent tablet after the seasoning, taste is better, and good medicine is no longer bitter to the taste, and patient is more taken like a shot.Because a large amount of foams that disintegration produces have increased medicine and have contacted with the direct of diseased region, bring into play its curative effect effect better, so effervescent tablet also is used for the control medication of mouth disease etc.Utilize up-to-date medicine quick releasing formulation technology, according to the effervescent tablet disintegration fast, taking convenience, onset speed be fast, a large amount of foams that disintegration produces increase chewing gum and the inner large-area characteristics that directly contact in oral cavity, research and develop novel oral health care product, for the further development that promotes China's MC industry, improve overall image and the influence of China's MC industry in consumers in general and international counterparts, have crucial reality and historic significance.
[summary of the invention]
First purpose of the present invention is to overcome deficiency of the prior art, provides to produce under a kind of saliva environment in the oral cavity that effervescence, disintegration rate are fast, the effervesce chewing gum of taking convenience.
Second purpose of the present invention provides a kind of preparation method of above-mentioned effervesce chewing gum.
In order to realize above-mentioned first purpose, by the following technical solutions:
A kind of effervesce chewing gum, it comprises:
Mass percent is the disintegrant of 20-90%, and it comprises basic component and acidic components, and basic component is selected from one of sodium carbonate, potash, sodium acid carbonate, saleratus or several mixture wherein; Acidic components are selected from one of citric acid, malic acid, tartaric acid, vitamin C or several mixture wherein, and the scope of the mass ratio of acidic components and basic component is 1.0-2.5;
Mass percent is the filler of 20-80%, and it selects one of lactose, sorbierite, sweet mellow wine, glucose, sucrose, starch, sodium carboxymethyl starch or several mixture wherein for use;
Mass percent is the adhesive of 3.0-15%, adhesive select for use concentration more than 95% ethanol or select for use PVP K-30 to be dissolved in the 2-10% solution that ethanol (concentration is more than 95%) is made.
Further technical scheme is also to comprise:
Flavouring, it comprises spices that accounts for effervesce chewing gum mass percent 1-2% and the sweetener that accounts for effervesce chewing gum mass percent 0-4%.
Further technical scheme is also to comprise again:
Mass percent is the lubricant of 1.5-5%, and it is selected from, and polyethylene glycol-6000, leucine, benzoic acid are received, one of dolomol, sodium stearyl fumarate, talcum powder, lauryl sodium sulfate, differential silica gel or several mixture wherein.
Further technical scheme is also to comprise again:
Colouring agent, its addition accounts for the 0.002-0.01% of effervesce chewing gum mass percent;
Further technical scheme is also to comprise again:
Functional component; it comprises one of vitamin C, vitamin E, taurine, collagen, peppermint, aloe extract, Chinese olive (blue or green olive) extract, green-tea extract, licorice, haw thorn extract, chrysanthemum extract, Honegsukle flower P.E, Scaphium scaphigerum extract, xylitol, FOS, mulberry fruit extract, borneol, dandelion or several mixture wherein, and its addition accounts for the 3-25% of effervesce chewing gum mass percent.
In order to realize above-mentioned second purpose, by the following technical solutions:
The preparation method of effervesce chewing gum, it comprises the steps:
1) supplementary material is handled: all material fineness reach more than 80 orders by processing;
2) weighing: by each material of prescription difference weighing;
3) preparation of adhesive: a, the direct ethanol of working concentration more than 95%; B, load weighted PVP K-30 is dissolved in the ethanol of concentration more than 95%, stirred 5~10 minutes, to evenly;
4) granulate: disintegrant, filler, sweetener, functional component are mixed back with adhesive system softwood, and make color even, and softwood is made wet granular with the 12-20 eye mesh screen;
5) drying: in 50~60 ℃ of oven dry 2~4 hours, water content was controlled at below 2.0%;
6) whole grain: adopt the whole grain of 10~16 eye mesh screens;
7) total mixing: add auxiliary material, always mixed 2~4 minutes;
8) compressing tablet: be pressed into tablet by specification with rotary tablet machine;
9) packing;
10) external packing;
11) vanning.
Advantage of the present invention:
The present invention utilizes medicine quick releasing formulation technology, and the change crowd uses the custom of chewing gum, avoids the pollution of matrix type residual gum matrix to environment thereby by other function compositions such as interpolation disintegrants product is had by the form that changes chewing gum.Acid-base reaction (effervescence) takes place and discharges a large amount of bubbles in the effervesce chewing gum in the saliva environment, and composition is slowly dissolved automatically, do not need to chew, do not need to overturn with tongue, the bubble that has dissolved active ingredient can make active ingredient soak into oral cavity, tooth fast, and faster, more thorough removing oral peculiar smell, swallowed or in the oral cavity, be absorbed easilier, experimental results show that, just can arrive whole oral cavity at the bubble liquid that uses product to contain active ingredient after 6 seconds, thereby play clean mouth, protect tooth and other health care; Make the chewing gum of effervescence type, the incomparable characteristics of chewing gum that also have other types, be exactly to make saliva become acidity behind the effervesce, help the more abundant ionization of functional component, helping the function composition is absorbed and used, experimental results show that, the functional component of making the chewing gum of effervesce form is improved 22.3% by the ratio that the oral cavity directly absorbs, after being swallowed, because functional component ionization is absorbed in that digestive system is also easier, with respect to matrix type chewing gum, effervescence type chewing gum 100% is absorbed or swallows, not residual, and matrix type product since functional component with after matrix mixes, though, the part composition is still arranged attached in the matrix by after fully chewing, finally told into dustbin, caused environmental pollution.
[specific embodiment]
Effervesce chewing gum of the present invention is by addition, disintegrant and filler, the lubricant of control disintegrant, and the interaction of functional component, flavouring, other compositions makes the slowly dissolving in the saliva environment of effervesce chewing gum.The material that described effervescent tablet uses comprises:
1, disintegrant: comprise basic component and acidic components, basic component is selected from one of sodium carbonate, potash, sodium acid carbonate, saleratus or several mixture wherein; Acidic components are selected from one of citric acid, malic acid, tartaric acid, vitamin C or several mixture wherein.The addition of disintegrant is 20-90%, calculates by weight; The scope of acidic components and basic component mass ratio is 1.0-2.5.
2, flavouring:, suitably add flavouring for improving the tablet bubble palatability after molten.Flavouring is divided into: spices and sweetener.Spices is selected for use and is met standard GB 2760 regulation and be fit to use artificial or natural perfume material with candy, and addition is 1-2%, calculates by weight; Sweetener: can select to add or do not add, addition is 0-4%, calculates by weight.
3, colouring agent: the colouring agent of interpolation must meet the kind that the GB2760 regulation is suitable for candy.Addition 0.002-0.01% calculates by weight.
4, lubricant: for the effect of improving compressing tablet and the smoothness that increases product, in manufacture process, intend to add lubricant, this lubricant be selected from one of polyethylene glycol-6000, leucine, Sodium Benzoate, dolomol, sodium stearyl fumarate, talcum powder, lauryl sodium sulfate, differential silica gel or several mixture wherein.This lubricant adds with outer addition, and addition is 1.5-5%, calculates by tablet weight.
5, filler: have good hardness in order to make tablet, add suitable filler, filler is selected one of lactose, sorbierite, sweet mellow wine, glucose, sucrose, starch, sodium carboxymethyl starch or several mixture wherein for use.Addition is 20-80%, calculates by weight.
6, adhesive: adhesive select for use concentration more than 95% ethanol or select for use PVP K-30 to be dissolved in the 2-10% solution that ethanol (concentration is more than 95%) is made; Addition is 3.0-15%, calculates by weight.
7, functional component: this effervesce chewing gum is for the function that increases its fresh breath and increase other health cares, is fit to different crowds according to product and adds: one of vitamin C, vitamin E, taurine, collagen, peppermint, aloe extract, Chinese olive (blue or green olive) extract, green-tea extract, licorice, haw thorn extract, chrysanthemum extract, Honegsukle flower P.E, Scaphium scaphigerum extract, xylitol, FOS, mulberry fruit extract, borneol, dandelion or several mixture wherein; Addition is 3-50%, calculates by weight.
Necessarily contain disintegrant (acidic components and basic component), filler, adhesive in the above-mentioned effervesce chewing gum, optionally contain or do not contain one of lubricant, flavouring, colouring agent, functional component or several mixture wherein.
This effervesce chewing gum is prepared as follows:
1) all material fineness reach more than 80 orders by processing, and finished product no grittiness in the molten process of Kou Zhongpao is existed.
2) preparation of adhesive: load weighted PVP K-30 is put into beaker, add concentration and be the distillation water-ethanol liquid dissolving more than 95%, stirred 5-10 minute, to even.
3) granulate: with adhesive system softwood, the softwood of making should be " that holds is agglomerating, and that touches promptly looses ", and makes color even after disintegrant, filler, sweetener, functional component were mixed, and softwood is made wet granular with 16 eye mesh screens.
4) drying: in 50-60 ℃ of oven dry 1-3 hour, water content was controlled at below 2.0%.
5) whole grain: adopt the whole grain of 10-16 eye mesh screen.
6) total mixing: add auxiliary material, always mixed 2-4 minute.
7) compressing tablet: be pressed into tablet by specification with rotary tablet machine.
Concrete preparation method's example of this effervesce chewing gum carries out as follows:
1. supplementary material is handled: all materials all reach more than 80 orders;
2. weighing: by each material of prescription difference weighing;
3. the preparation of adhesive: load weighted PVP K-30 is put into beaker, add concentration and be the distillation water-ethanol liquid dissolving more than 95%, stirred 5-10 minute, to even;
4. system softwood, granulation: with adhesive system softwood, the softwood of making should be " that holds is agglomerating, and that touches promptly looses ", and makes color even after disintegrant, filler, sweetener, functional component were mixed, and softwood is made wet granular with the 12-20 eye mesh screen;
5. dry: in 20-60 ℃ of oven dry 2-4 hour, water content had been controlled at below 2.0%;
6. whole grain: adopt the whole grain of 10-16 eye mesh screen;
7. total mixing: add auxiliary material, always mixed 2-4 minute;
8. compressing tablet: be pressed into tablet by specification with rotary tablet machine;
9. packing;
10. external packing;
11. vanning.
Provide the concrete component example of effervesce chewing gum of the present invention below:
Embodiment one
Each component of effervesce chewing gum is referring to table 1 in the present embodiment.
Table 1
Figure BDA0000057579570000061
Figure BDA0000057579570000071
Embodiment two
Each component of effervesce chewing gum is referring to table 2 in the present embodiment.
Table 2
Figure BDA0000057579570000072
Embodiment three
Each component of effervesce chewing gum is referring to table 3 in the present embodiment.
Table 3
Figure BDA0000057579570000081
Embodiment four
Each component of effervesce chewing gum is referring to table 4 in the present embodiment.
Table 4
Figure BDA0000057579570000082
Embodiment five
Each component of effervesce chewing gum is referring to table 5 in the present embodiment.
Table 5
Embodiment six
Each component of effervesce chewing gum is referring to table 6 in the present embodiment.
Table 6
Figure BDA0000057579570000101
The effervesce chewing gum of above-mentioned six instantiation proportionings all can be realized beneficial effect of the present invention.
Above embodiment is the unrestricted technical scheme of the present invention in order to explanation only, does conspicuous change according to the prompting of the foregoing description, and other every changes that do not break away from essence of the present invention, all should be included within the described scope of claim.

Claims (6)

1. an effervesce chewing gum is characterized in that, comprising:
Mass percent is the disintegrant of 20-90%, and it comprises basic component and acidic components, and basic component is selected from one of sodium carbonate, potash, sodium acid carbonate, saleratus or several mixture wherein; Acidic components are selected from one of citric acid, malic acid, tartaric acid, vitamin C or several mixture wherein, and the scope of the mass ratio of acidic components and basic component is 1.0-2.5;
Mass percent is the filler of 20-80%, and it selects one of lactose, sorbierite, sweet mellow wine, glucose, sucrose, starch, sodium carboxymethyl starch or several mixture wherein for use;
Mass percent is the adhesive of 3.0-15%, adhesive select for use concentration more than 95% ethanol or select for use PVP K-30 to be dissolved in the 2-10% solution that ethanol (concentration is more than 95%) is made.
2. effervesce chewing gum according to claim 1 is characterized in that, also comprises:
Flavouring, it comprises spices that accounts for effervesce chewing gum mass percent 1-2% and the sweetener that accounts for effervesce chewing gum mass percent 0-4%.
3. effervesce chewing gum according to claim 2 is characterized in that, also comprises:
Mass percent is the lubricant of 1.5-5%, and it is selected from, and polyethylene glycol-6000, leucine, benzoic acid are received, one of dolomol, sodium stearyl fumarate, talcum powder, lauryl sodium sulfate, differential silica gel or several mixture wherein.
4. effervesce chewing gum according to claim 3 is characterized in that, also comprises:
Colouring agent, its addition accounts for the 0.002-0.01% of effervesce chewing gum mass percent.
5. effervesce chewing gum according to claim 4 is characterized in that, also comprises:
Functional component; it comprises one of vitamin C, vitamin E, taurine, collagen, peppermint, aloe extract, Chinese olive (blue or green olive) extract, green-tea extract, licorice, haw thorn extract, chrysanthemum extract, Honegsukle flower P.E, Scaphium scaphigerum extract, xylitol, FOS, mulberry fruit extract, borneol, dandelion or several mixture wherein, and its addition accounts for the 3-25% of effervesce chewing gum mass percent.
6. the preparation method of effervesce chewing gum is characterized in that, comprises the steps:
1) supplementary material is handled: all material fineness reach more than 80 orders by processing;
2) weighing: by each material of prescription difference weighing;
3) preparation of adhesive: a, the direct ethanol of working concentration more than 95%; B, load weighted PVP K-30 is dissolved in the ethanol of concentration more than 95%, stirred 5~10 minutes, to evenly;
4) granulate: disintegrant, filler, sweetener, functional component are mixed back with adhesive system softwood, and make color even, and softwood is made wet granular with the 12-20 eye mesh screen;
5) drying: in 50~60 ℃ of oven dry 2~4 hours, water content was controlled at below 2.0%;
6) whole grain: adopt the whole grain of 10~16 eye mesh screens;
7) total mixing: add auxiliary material, always mixed 2~4 minutes;
8) compressing tablet: be pressed into tablet by specification with rotary tablet machine;
9) packing;
10) external packing;
11) vanning.
CN2011101054518A 2011-04-26 2011-04-26 Effervescent chewing gum and preparation method thereof Pending CN102210453A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN2011101054518A CN102210453A (en) 2011-04-26 2011-04-26 Effervescent chewing gum and preparation method thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN2011101054518A CN102210453A (en) 2011-04-26 2011-04-26 Effervescent chewing gum and preparation method thereof

Publications (1)

Publication Number Publication Date
CN102210453A true CN102210453A (en) 2011-10-12

Family

ID=44742165

Family Applications (1)

Application Number Title Priority Date Filing Date
CN2011101054518A Pending CN102210453A (en) 2011-04-26 2011-04-26 Effervescent chewing gum and preparation method thereof

Country Status (1)

Country Link
CN (1) CN102210453A (en)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103815111A (en) * 2014-03-03 2014-05-28 安徽科技学院 Health chuzhou chrysanthemum chewing gum and production method thereof
CN104983610A (en) * 2015-06-16 2015-10-21 杭州大茗堂生物科技有限公司 Product formula for preventing caries and removing bad breath
CN107510747A (en) * 2017-08-04 2017-12-26 上海中华药业南通有限公司 A kind of effervescent tablet for rinsing mouth and preparation method thereof
WO2022187989A1 (en) * 2021-03-07 2022-09-15 Wm Wrigley Jr. Company Chewing gum compositions for skin benefits

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1720810A (en) * 2004-07-16 2006-01-18 王桂凤 A cool sugar tablet with fruit flavor and its production process
CN101249098A (en) * 2008-04-11 2008-08-27 温州医学院 Polygonatum polysaccharide effervescence tablet

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1720810A (en) * 2004-07-16 2006-01-18 王桂凤 A cool sugar tablet with fruit flavor and its production process
CN101249098A (en) * 2008-04-11 2008-08-27 温州医学院 Polygonatum polysaccharide effervescence tablet

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103815111A (en) * 2014-03-03 2014-05-28 安徽科技学院 Health chuzhou chrysanthemum chewing gum and production method thereof
CN103815111B (en) * 2014-03-03 2015-04-22 安徽科技学院 Health chuzhou chrysanthemum chewing gum and production method thereof
CN104983610A (en) * 2015-06-16 2015-10-21 杭州大茗堂生物科技有限公司 Product formula for preventing caries and removing bad breath
CN104983610B (en) * 2015-06-16 2018-10-16 浙江大茗堂生物科技有限公司 A kind of product formula for anti-caries removing abnormal flavor in oral cavity
CN107510747A (en) * 2017-08-04 2017-12-26 上海中华药业南通有限公司 A kind of effervescent tablet for rinsing mouth and preparation method thereof
WO2022187989A1 (en) * 2021-03-07 2022-09-15 Wm Wrigley Jr. Company Chewing gum compositions for skin benefits

Similar Documents

Publication Publication Date Title
CN101919801B (en) Solid effervescent mixture for oral absorption
TW586941B (en) Quickly disintegratable pharmaceutical composition
CN101010091A (en) Oral care composition comprising essential oils
JP2001527518A (en) Suppression of undesirable taste in oral compositions
CN101547609A (en) Oral delivery vehicles containing a traditional chinese medicine of extract thereof
CN103751327A (en) Zinc gluconate VC (Vitamin C) effervescent tablet
CN100556401C (en) Effervescence tablet for cold
CZ170296A3 (en) Organoleptic acceptable pharmaceutical preparation for peroral administration
CN105310960A (en) Novel polysaccharide antibacterial mouthwash and preparation method thereof
CN100546571C (en) Sangju effervescent tablet for treating common cold
CN110314110A (en) A kind of effervescent tablet type mouthwash and preparation method thereof
CN102210453A (en) Effervescent chewing gum and preparation method thereof
AU2018203085A1 (en) Effervescent composition and method of making it
CN105902512A (en) Olaparib effervescent tablet and preparation method thereof
WO2005084703A1 (en) Sustained-release composition for oral cavity
CN105381019A (en) Effervescent tablet with internal-fire clearing function and preparation method thereof
CN1895602A (en) Externally-applied female effervescent tablet for preventing and treating gynecological disease
CN106074429A (en) A kind of Vonoprazan fumarate effervescent tablet and preparation method thereof
CN102836165A (en) Aspirin vitamin C effervescent tablet and preparation technology thereof
CN108992480A (en) Honeysuckle chrysanthemum effervescent tablets and preparation method thereof
CN100542520C (en) Lonicera and Forsythia effervescent
CN102100902A (en) Counterflow cold effervescent tablets
CN109198352A (en) A kind of propolis solid beverage powder and preparation method thereof
CN100546570C (en) Effervescence tablet for treating wind-cold type cold
CN101176698A (en) Product and method for eliminating oral cavity bitter

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C12 Rejection of a patent application after its publication
RJ01 Rejection of invention patent application after publication

Application publication date: 20111012