CN102125180B - Composition and application thereof to feed for fetus protection on 0 to 35th days of pregnant sow - Google Patents

Composition and application thereof to feed for fetus protection on 0 to 35th days of pregnant sow Download PDF

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CN102125180B
CN102125180B CN201010609128XA CN201010609128A CN102125180B CN 102125180 B CN102125180 B CN 102125180B CN 201010609128X A CN201010609128X A CN 201010609128XA CN 201010609128 A CN201010609128 A CN 201010609128A CN 102125180 B CN102125180 B CN 102125180B
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张丽萍
安晓芳
许锐
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Henan Superfriend Science AND Technology Co., Ltd.
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Henan Superfriend Science & Technology Co Ltd
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Abstract

The invention belongs to the technical field of feed and in particular relates to a composition and application thereof to feed for preventing miscarriage on 0 to 35th days of sow pregnancy. The composition comprises the following components of boar composite multivitamin, beneficial microorganism mixed fermented product, phytase, lysine, monohydrate ferrous sulphate, ferrous fumarate, bluevitriod, monohydrate zinc sulphate, zinc fumarate, monohydrate manganese sulphate, potassium iodide, sodium selenite, organic chromium, vitamin C, vitamin E, beta-carotene, calcium hydrophosphate, rock flour, choline chloride, salt, puffed soybean, fermented bean pulp, puffed bean pulp, electrolyte poising agent, antioxidant, mildew preventive and bran hull powder, wherein the equivalent weight of the beneficial microorganism mixed fermented product viable bacteria is more than 5 billion per gram. By the composition and the application thereof, addition of nutrients associated with embryonic implantation, growth and environment in a womb is emphasized; a good pregnancy environment is built; embryonic healthy growth is guaranteed; embryonic survival rate is increased; and birth weight and survival rate of the piglets are increased.

Description

A kind of composition and the application in sow gestation 0-35 days feeds of preventing miscarriage thereof
Technical field
The invention belongs to field of feed, particularly a kind of composition and the application in sow gestation 0-35 days feeds of preventing miscarriage thereof.
Background technology
Count potentiality following statistics is arranged about every sow piglet that on average goes out to live: Denmark reached 25/year in 2002, reached 32/year in 2005; 22 of external average out to, wherein 10% above sow reaches 25.6/year; Present status in China is 18/year.At present, modern goods sow number of eggs ovulated can reach more than 19 pieces, and rate of fertilization supposes to have 17 pieces successfully to become pregnant more than 95%, but has finally born 10 piggys, and then rate of embryonic death is 41.18%.
Sow is from weaning the back in pregnant 35 days, and its hormone in vivo changes very complicated.The variable effect of hormone oestrus, ovulation and survival rate of embryo, be the key point of whole breeding cycle.The degree of stability of embryo nidation receives the manipulation of hormone in vivo secretion level in back 35 days of the sow postweaning estrus, ovulation, breeding, breeding.Estrogen (E 2) stimulate hypothalamus through positive feedback, promote promoting sexual gland hormone particularly luteinizing principle (LH) and follicular stimulating hormone (FSH) secretion.
Following from a process of the gestation of breeding:
(1) follicular development, ovulation: FSH concentration raises, and increases ovarian follicle and raises quantity.The reduction of FSH concentration, LH and E 2Concentration raises, dominant follicle advantageization, maturation.E 2And LH: promote ovarian follicle to grow rapidly, until ovulation.
(2) plant relevant factor with attaching: estrogen makes endometrial hyperplasia, and progesterone makes that endometrial secretion is movable to be strengthened, and deciduaization takes place.Progesterone and estrogenic acting in conjunction make the uterus accept attaching of blastaea to plant.The embryo began at 13 days, accomplished to attach by 18-24 days and planted.
FSH concentration is the same with LH, of short duration rising before ovulation, and form a peak.And progesterone levels is kept reduced levels before ovulation.Estrogen just begins slow rising before the LH peak occurs, LH peak 12h before appearance sharply raises, and maximum occurs reaching the same day at the peak, descends rapidly later on.
(3) breeding-gestation is 35 days: according to the nutrition regulation mechanism of early embryo development, the blastocyst of the state of activation and the uterus of accepting attitude are carried out synchronously, accurately accomplish and attach the activity of planting.
Gestation was stages of embryonic cell meiosis, differentiation and early growth and development in 0-35 days, was the peak period of embryonic death, embryo loss in this period 80% with attach plant get nowhere relevant.
Summary of the invention
The object of the present invention is to provide a kind of composition and the application in sow gestation 0-35 days feeds of preventing miscarriage thereof, said composition can improve piglet nest litter size and nest piglet birth weight.
The technical scheme that the present invention adopts is following:
A kind of composition, per 1000 mass parts of described composition are formed as follows:
Boar compound vitamin 1.3-1.5 part, beneficial microbe mixed culture fermentation product 7.5-8.5 part, 0.2 part of phytase, lysine 1.9-2.2 part; Ferrous sulfate monohydrate 1.3-1.5 part, ferrous fumarate 0.5-0.7 part, cupric sulfate pentahydrate 0.2-0.3 part, monohydrate zinc sulphate 0.9-1.0 part; Zinc fumarate 0.5-0.7 part, manganese sulfate monohydrate 1.5-1.7 part, KI 0.2-0.25 part, sodium selenite 0.1-0.3 part; Organic Chromium 0.5-0.7 part, vitamin C 1.9-2.0 part, vitamin E 0.3-0.45 part, beta carotene 1.1-1.3 part; Calcium monohydrogen phosphate 63-65 part, stone flour 59-62 part, Choline Chloride 7.9-8.1 part, salt 19-21 part; Expanded soybean 297-303 part, fermented bean dregs 99-101 part, swelling soya dreg 399-407 part, electrolyte balance agent 11-13 part; Anti-oxidant 0.3-0.45 part, mould inhibitor 0.3-0.45 part, litter shell powder 0-22 part; Wherein beneficial microbe mixed culture fermentation product viable bacteria equivalent is greater than 5,000,000,000/gram.
Wherein the content of Organic Chromium is 0.1% to add according to chromium content wherein, specifically can select chromium picolinate for use; Content of choline is 50% in the Choline Chloride, and protein content is respectively 35%, 50% and 43% in expanded soybean, fermented bean dregs, the swelling soya dreg, if corresponding content is different, can convert according to this content.
The boar compound vitamin is the boar B B-complex, the DSM boar compound vitamin that the preferred DSM of the present invention (Shanghai) Co., Ltd. produces, and authentication code is that preparatory word (2006) 703530 is raised in Shanghai.
The preferred DSM phytase of phytase the present invention is readily taken the opportunity to phosphorus 50K (50000 FYT/g), and letter (China) Bioisystech Co., Ltd of Novi produces, and Tianjin is raised and added word (2007) 004011.
Said beneficial microbe mixed culture fermentation product main component is beneficial microbes such as bacillus, Bacillus acidi lactici, photosynthetic bacteria, saccharomyces cerevisiae, its useful total viable count>=5 * 10 9/ g; It can sell product for ordinary city, perhaps with buying commercially available bacterial classification and zymotic fluid, promptly gets according to the preparation of this area common process.Probiotics of the present invention selects for use the rich modern natural farm bloc of SeaBird to produce, and lot number: Shanghai is raised and added word (2010) 127379.
The electrolyte balance agent preferably must be beautiful, U.S. Mosic Potash Carlsbad company imported product.
The lysine purity of selecting for use is 98.5%.
Described composition had good application at sow gestation 0-35 days in the feed of preventing miscarriage, and described composition is added in the conventional feed process, and the mass ratio of described composition in feed is 20-30%.Tryptophan and arginine content all are higher than NRC (1998) standard and GB (2004) recommended amounts to gestational period sow in the feed that obtains.
Concrete, described feeding quality percentage composition is: corn 60-70%, wheat bran 10-15%, composition 20-30%.More preferably following ratio: corn 65%, wheat bran 10%, composition 25%.
Extract of the present invention has following characteristics:
1, pays close attention to uterus health, environment in the high-quality is provided for the embryo attaches to plant
(1) optimize and to be beneficial to the embryo and to attach the environment of planting: the present invention is applied to beneficial microbe mixed culture fermentation product in the sow feed, can clean genital tract, safeguard the interior environment of a suitable embryonic development.
(2) contain multivitamin in the boar multidimensional: liposoluble vitamin VA is mainly relevant with functional integrity with the maintenance membrane structure, and the complete of membrane structure is the basis that immunity plays a role; Beta carotene can be through stimulating the synthetic of ovary steroids and improving the reproduction function that intrauterine environment improves pig; VE, VC, beta carotene can strengthen cell and humoral immunity.
2, pay close attention to embryo's effective nutrition and safeguard protection, be beneficial to embryo survival
Enriched nutritive embryo's extraordinary nutrient; Guarantee embryo's normal development: (1) arginine: all contain in swelling soya dreg, expanded soybean, fermented bean dregs the inside; In order to synthetic NO, regulate the blood flow between placenta and the fetus, regulate parent nutrition and carry to fetus; Embryonic development is played an important role, participate in E simultaneously 2Regulate the effect of embryo nidation; (2) VA transcribes and directly influences embryonic development through cell differentiation and propagation or through special genes, and also the ovary steroid hormone is synthetic through regulating, immune cell function and interferon generate and the remote-effects embryonic development; (3) folic acid is participated in the synthetic of purine, the needs when satisfying the first half period of gestation embryo and growing at a high speed; (4) tryptophan that all contains of swelling soya dreg, expanded soybean, fermented bean dregs the inside is the growth of blastaea and attaches to plant and need amino acid that nutrition is provided.
3, remove the antioxidant radical of harmful product, improve embryo survival
(1) VE can remove a large amount of lipid free radicals that produce in the early embryonic development process as the stronger free radical scavenger of function, reduces the damage that blastular causes lipid peroxidation; (2) selenium is the important component of glutathione peroxidase, and it can reduce all peroxide becomes nontoxic hydroxy compounds, makes cell avoid the murder by poisoning of peroxide; (3) VA can transcribe and directly influences embryonic development through cell differentiation and propagation or through special genes, also maybe the ovary steroid hormone is synthetic through regulating, immune cell function and interferon generate and the remote-effects embryonic development; (4) folic acid is participated in the synthetic of purine, avoids lacking period in embryo's high-speed separation.
4, regulate the micronutrient of pregnancy maintenance hormone secretion, improve the embryo and attach the success rate of planting
(1) organic zinc promotes hypophysis to discharge promoting sexual gland hormone LH, FSH, is adrenocortical proper constituent, and hypothalamus-hypophysis-gonad axis functional activity is played coordinative role.(2) insulin in chromium and the organism is collaborative, and IGF-I stimulates the placenta synthetic protein, and is relevant with immunosupress with maternal gestational identification.IGF-II has important function to growing of fetus; (3) manganese is participated in the synthetic of cholesterol and precursor thereof, participates in the ovary steroid hormone and synthesizes; (4) iodine promotes thyroxinic synthesizing, and thyroxine is relevant with hypothalamus-hypophysis-gonad axis function.
With respect to prior art, beneficial effect of the present invention is:
The present invention strengthened emphatically attach with the embryo plant, the interpolation of nutrient that growth, intrauterine environment are relevant, build good pregnant environment, ensure that embryo health grows, improve embryo survival; Improve piglet birth weight and piglet survival ratio.
The specific embodiment
Below with specific embodiment technical scheme of the present invention is described, but protection scope of the present invention is not limited thereto:
Each constituent mass umber of embodiment 1-3 is as shown in table 1 below:
Figure 323437DEST_PATH_IMAGE001
Anti-oxidant is an ethoxyquinoline in the table, and content is 30%.Said mould inhibitor is the mixture of the 1:1 of fumaric acid and calcium propionate, adopts other commercial like product also passable.Mould inhibitor is mainly in the interpolation of summer and autumn property.
The result of use example
For checking result of use of the present invention, do contrast with conventional feed, the feed that specifically adopts the model SB54 of Henan Superfriend Science & Technology Co., Ltd. to be mixed with is done contrast test.The SB54 authentication code is that preparatory word (2010) 026004 is raised in Henan.
1, test place
Henan Xiong Feng Si lattice boar Co., Ltd.
2, experimental design
Select 48 the first-born Du * length binary sows close, that the expected date of childbirth is close in age to make an experiment; Be divided into 4 groups at random; Every group 12; 0-35 days control groups of feeding respectively of gestation, 1 group of test, 2 groups of tests, 3 groups of daily rations of test, the pregnant 36-90 days same daily rations of feeding, 91 days-childbirth-wean of the gestation same daily ration of feeding.
The daily ration of specifically feeding is following: (1) pregnant 0-35 days: the mixed feed that the present invention that feeds respectively is mixed with, and the mixed feed of preparing with SB54 compares; (2) 36 days-childbirth of gestation: it is identical that each organizes the daily ration of feeding, but pregnant 36-90 days, feed by the mixed feed of SB54 preparation 91 days-childbirth of gestation, the mixed feed of feeding and being mixed with by SB64.The mixed feed composition of SB54 preparation is seen table 2.
SB64 feed-grain maker produces for Henan Superfriend Science & Technology Co., Ltd., and authentication code is that preparatory word (2010) 026005 is raised in Henan.The mixed feed of SB64 preparation is formed as follows: corn 62%, dregs of beans 19%, wheat bran 10%, fish meal 3%, soya-bean oil 2%, SB64 feed 4%.
,0-35 days daily rations of feeding of gestation are seen table 2
Table 2
Figure 144948DEST_PATH_IMAGE004
4, detect index
A 4.1 nest birth piglet number
The counterpoise 4.2 the nest piglet is come into being
5, data
The result representes with " average ± standard deviation "; The conspicuousness statistics adopts the one-way analysis of variance of SAS8.0 statistical software, and carries out the DuncanShi multiple ratio, and P<0.01 differential heteropole is remarkable; < 0.05 expression significant difference, there is trend in 0.05 < P < 0.10 expression to P.
6, result of the test is seen table 3.
Table 3 control group and test group nest litter size and nest piglet birth weight
Figure 540158DEST_PATH_IMAGE006
Annotate: identical or do not have letter representation difference not significantly (P>0.05) with line data shoulder mark lowercase, the complete different table differential of lowercase different significantly (P < 0.05), the complete different table differential of capitalization heteropole is (P < 0.01) significantly.
During α=0.05 level, all there are significant difference (P≤0.0001) in nest litter size, nest piglet birth counterpoise test group and control group, and difference is not remarkable between the test group, and test group 2 is higher.
Result of the test shows that product of the present invention has increases nest litter size and the effect that improves nest piglet counterpoise.

Claims (4)

1. a composition is characterized in that, per 1000 mass parts of described composition are formed as follows:
Boar compound vitamin 1.3-1.5 part, beneficial microbe mixed culture fermentation product 7.5-8.5 part, 0.2 part of phytase, lysine 1.9-2.2 part; Ferrous sulfate monohydrate 1.3-1.5 part, ferrous fumarate 0.5-0.7 part, cupric sulfate pentahydrate 0.2-0.3 part, monohydrate zinc sulphate 0.9-1.0 part; Zinc fumarate 0.5-0.7 part, manganese sulfate monohydrate 1.5-1.7 part, KI 0.2-0.25 part, sodium selenite 0.1-0.3 part; Organic Chromium 0.5-0.7 part, vitamin C 1.9-2.0 part, vitamin E 0.3-0.45 part, beta carotene 1.1-1.3 part; Calcium monohydrogen phosphate 63-65 part, stone flour 59-62 part, Choline Chloride 7.9-8.1 part, salt 19-21 part; Expanded soybean 297-303 part, fermented bean dregs 99-101 part, swelling soya dreg 399-407 part, electrolyte balance agent 11-13 part; Anti-oxidant 0.3-0.45 part, mould inhibitor 0.3-0.45 part, litter shell powder 0-22 part; Wherein beneficial microbe mixed culture fermentation product viable bacteria equivalent is greater than 5,000,000,000/gram, and its composition is bacillus, Bacillus acidi lactici, photosynthetic bacteria, saccharomyces cerevisiae.
2. the application of the described composition of claim 1 in 0-35 days feeds of preventing miscarriage of preparation sow gestation is characterized in that the mass ratio of described composition in feed is 20-30%.
3. the application of composition as claimed in claim 2 in 0-35 days feeds of preventing miscarriage of preparation sow gestation is characterized in that described feeding quality percentage composition is: corn 60-70%, wheat bran 10-15%, composition 20-30%.
4. the application of composition as claimed in claim 3 in 0-35 days feeds of preventing miscarriage of preparation sow gestation is characterized in that described feeding quality percentage composition is: corn 65%, wheat bran 10%, composition 25%.
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CN102578392A (en) * 2012-03-19 2012-07-18 周洁 Animal healthcare product capable of preventing dysentery
CN102599390A (en) * 2012-04-11 2012-07-25 宜章县梅田镇石子岭综合养殖场 Feed for replacement gilts
CN102907582A (en) * 2012-10-25 2013-02-06 淮安正昌饲料有限公司 Feed for treating abdominal distension of pregnant sows
CN103844030A (en) * 2012-12-04 2014-06-11 广西商大科技有限公司 Nutritive feed additive capable of increasing survival ratio of embryos in first half period of cow gestation
CN103535553A (en) * 2013-10-23 2014-01-29 遵义市金鼎农业科技有限公司 Chrysanthemum meal-containing feeds for pregnant sows
CN104322882A (en) * 2014-11-25 2015-02-04 河南联合英伟饲料有限公司 Complete formula feed capable of improving production performances of sows
CN104872411B (en) * 2015-04-30 2019-04-19 河南民正农牧股份有限公司 A kind of gestational period sow method for breeding

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Address after: 450000 Henan city in Zhengzhou province Xin Yuan Road No. 26 building 11 Yasuhiro

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