CN102108406B - 检测胚胎染色体拷贝数的试剂盒、装置和方法 - Google Patents
检测胚胎染色体拷贝数的试剂盒、装置和方法 Download PDFInfo
- Publication number
- CN102108406B CN102108406B CN201010595234.7A CN201010595234A CN102108406B CN 102108406 B CN102108406 B CN 102108406B CN 201010595234 A CN201010595234 A CN 201010595234A CN 102108406 B CN102108406 B CN 102108406B
- Authority
- CN
- China
- Prior art keywords
- dna
- karyomit
- interval
- chromosome
- point
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Images
Landscapes
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Abstract
Description
Claims (12)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201010595234.7A CN102108406B (zh) | 2010-12-20 | 2010-12-20 | 检测胚胎染色体拷贝数的试剂盒、装置和方法 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201010595234.7A CN102108406B (zh) | 2010-12-20 | 2010-12-20 | 检测胚胎染色体拷贝数的试剂盒、装置和方法 |
Publications (2)
Publication Number | Publication Date |
---|---|
CN102108406A CN102108406A (zh) | 2011-06-29 |
CN102108406B true CN102108406B (zh) | 2014-05-21 |
Family
ID=44172691
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201010595234.7A Active CN102108406B (zh) | 2010-12-20 | 2010-12-20 | 检测胚胎染色体拷贝数的试剂盒、装置和方法 |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN102108406B (zh) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PL2716766T3 (pl) * | 2011-05-31 | 2017-09-29 | Berry Genomics Co., Ltd. | Urządzenie do wykrywania liczby kopii chromosomów płodowych lub chromosomów komórek nowotworowych |
CN103298955B (zh) * | 2012-01-10 | 2016-06-08 | 北京贝瑞和康生物技术股份有限公司 | 用于构建血浆dna测序文库的方法和试剂盒 |
WO2014101126A1 (zh) * | 2012-12-28 | 2014-07-03 | 深圳华大基因医学有限公司 | 确定胎儿性别的方法、***和计算机可读介质 |
CN104951671B (zh) * | 2015-06-10 | 2017-09-19 | 东莞博奥木华基因科技有限公司 | 基于单样本外周血检测胎儿染色体非整倍性的装置 |
CN106591451B (zh) * | 2016-12-14 | 2020-06-23 | 北京贝瑞和康生物技术有限公司 | 测定胎儿游离dna含量的方法及其用于实施该方法的装置 |
CN107217308A (zh) * | 2017-06-21 | 2017-09-29 | 北京贝瑞和康生物技术股份有限公司 | 一种用于检测染色体拷贝数变异的测序文库构建方法和试剂盒 |
CN108804873A (zh) * | 2018-06-29 | 2018-11-13 | 首度生物科技(苏州)有限公司 | 无创检测母体和胚胎遗传异常的装置 |
CN109402247B (zh) * | 2018-11-06 | 2020-04-07 | 苏州首度基因科技有限责任公司 | 一种基于dna变异计数的胎儿染色体检测*** |
CN112301103B (zh) * | 2019-08-02 | 2023-04-11 | 北京贝瑞和康生物技术有限公司 | 一种非特异性扩增天然短片段核酸的方法和试剂盒 |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101619346A (zh) * | 2008-07-04 | 2010-01-06 | 上海交通大学医学院附属瑞金医院 | 人冠心病易感基因-脂蛋白a基因拷贝数变异检测方法和试剂盒 |
CN101675169A (zh) * | 2006-06-14 | 2010-03-17 | 阿耳特弥斯保健公司 | 使用样品拆分和dna标签进行稀有细胞分析 |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP5262230B2 (ja) * | 2007-03-28 | 2013-08-14 | 独立行政法人理化学研究所 | 新規多型検出法 |
-
2010
- 2010-12-20 CN CN201010595234.7A patent/CN102108406B/zh active Active
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101675169A (zh) * | 2006-06-14 | 2010-03-17 | 阿耳特弥斯保健公司 | 使用样品拆分和dna标签进行稀有细胞分析 |
CN101619346A (zh) * | 2008-07-04 | 2010-01-06 | 上海交通大学医学院附属瑞金医院 | 人冠心病易感基因-脂蛋白a基因拷贝数变异检测方法和试剂盒 |
Also Published As
Publication number | Publication date |
---|---|
CN102108406A (zh) | 2011-06-29 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN102108406B (zh) | 检测胚胎染色体拷贝数的试剂盒、装置和方法 | |
CN103080336B (zh) | 检测胚胎或肿瘤染色体拷贝数的试剂盒、装置和方法 | |
JP7506408B2 (ja) | 血漿dnaの単分子配列決定 | |
CN105189748B (zh) | 测序免疫组库的方法 | |
KR101489568B1 (ko) | 태아 유전학적 이상의 비침습성 검출 | |
ES2620294T3 (es) | Diagnóstico no invasivo de la aneuploidia fetal por secuenciación | |
CN104169929B (zh) | 用于确定胎儿是否存在性染色体数目异常的***和装置 | |
WO2013053183A1 (zh) | 对核酸样本中预定区域进行基因分型的方法和*** | |
WO2016011414A1 (en) | Non-invasive prenatal diagnosis of fetal genetic condition using cellular dna and cell free dna | |
US20120003635A1 (en) | Diagnosing fetal chromosomal aneuploidy using massively parallel genomic sequencing | |
CN104350158A (zh) | 快速非整倍性检测 | |
CN107077537A (zh) | 用短读测序数据检测重复扩增 | |
BRPI0814670B1 (pt) | Método para realizar diagnóstico pré-natal de uma aneuploidia cromossômica fetal e meio legível por computador. | |
CA2796822A1 (en) | Measurement and comparison of immune diversity by high-throughput sequencing | |
KR102505860B1 (ko) | 자간전증에 특이적인 순환 rna 시그니처 | |
EP2563937A1 (en) | Method for determining the presence or absence of different aneuploidies in a sample | |
CN103298955A (zh) | 用于构建血浆dna测序文库的方法和试剂盒 | |
AU2015263055B2 (en) | Sequencing process | |
CN107893116A (zh) | 用于检测基因突变的引物对组合、试剂盒以及构建文库的方法 | |
US11710565B2 (en) | Method of detecting fetal chromosomal aneuploidy | |
WO2015196752A1 (en) | A method and a kit for quickly constructing a plasma dna sequencing library | |
CN108475301A (zh) | 用于确定包含核酸的混合物的样品中的拷贝数变异的方法 | |
KR101907650B1 (ko) | 비침습적 태아 염색체 이수성 판별 방법 | |
KR20170036649A (ko) | 비침습적 태아 염색체 이수성 판별 방법 | |
CN108611410B (zh) | N6-甲基腺嘌呤在自身免疫性疾病的用途 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
C06 | Publication | ||
PB01 | Publication | ||
C10 | Entry into substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
C14 | Grant of patent or utility model | ||
GR01 | Patent grant | ||
EE01 | Entry into force of recordation of patent licensing contract |
Application publication date: 20110629 Assignee: Hunan Jiahui Biological Technology Co., Ltd. Assignor: Beijing Berry Genomics Co., Ltd. Contract record no.: 2014430000143 Denomination of invention: Kit, device and method for detecting copy number of embryo chromosomes Granted publication date: 20140521 License type: Exclusive License Record date: 20140725 |
|
LICC | Enforcement, change and cancellation of record of contracts on the licence for exploitation of a patent or utility model | ||
ASS | Succession or assignment of patent right |
Owner name: HANGZHOU BERRY GENOMICS GENE DIAGNOSIS TECHNOLOGY Free format text: FORMER OWNER: BEIJING BERRY GENOMICS CO., LTD. Effective date: 20150317 |
|
C41 | Transfer of patent application or patent right or utility model | ||
COR | Change of bibliographic data |
Free format text: CORRECT: ADDRESS; FROM: 102206 CHANGPING, BEIJING TO: 310018 HANGZHOU, ZHEJIANG PROVINCE |
|
TR01 | Transfer of patent right |
Effective date of registration: 20150317 Address after: 1, No. 452, No. 6, No. 310018, Poplar Street, Hangzhou economic and Technological Development Zone, Zhejiang, 5B22 Patentee after: Auspicious and the health gene diagnosis Technology Co., Ltd. of Hangzhou shellfish Address before: 102206 B-246, life road, Changping District, Beijing Patentee before: Beijing Berry Genomics Co., Ltd. |
|
EC01 | Cancellation of recordation of patent licensing contract |
Assignee: Hunan Jiahui Biological Technology Co., Ltd. Assignor: Auspicious and the health gene diagnosis Technology Co., Ltd. of Hangzhou shellfish Contract record no.: 2014430000143 Date of cancellation: 20160722 |
|
EM01 | Change of recordation of patent licensing contract |
Change date: 20160722 Contract record no.: 2014430000143 Assignor after: Auspicious and the health gene diagnosis Technology Co., Ltd. of Hangzhou shellfish Assignor before: Beijing Berry Genomics Co., Ltd. |
|
LICC | Enforcement, change and cancellation of record of contracts on the licence for exploitation of a patent or utility model |