CN102090506B - Compound Chinese medicinal herbal additive for promoting growth of cadpigs and preparation method thereof - Google Patents
Compound Chinese medicinal herbal additive for promoting growth of cadpigs and preparation method thereof Download PDFInfo
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Abstract
The invention discloses a compound Chinese medicinal herbal additive for promoting the growth of cadpigs and a preparation method thereof. At present, most of Chinese medicinal herbal additives on the market are obtained by simply detecting and screening raw materials, so the active ingredient content of the additives is unstable, even the content of ingredients really beneficial to the growth of the cadpigs is very low and rigor-off and weight increasing effects are unremarkable. Therefore, the growth-promoting compound Chinese medicinal herbal additives with high-purity active ingredients are more required on the market. The compound Chinese medicinal herbal additive comprises the following components by weight: 6 kilograms of astragalus, 2 kilograms of codonopsis pilosula, 2 kilograms of Chinese pulsatilla root, 1 kilogram of malt flour, 2 kilograms of garlic, 4 kilograms of liquoric root, 3 kilograms of gentian, 380.54 milligrams of trace element, 287 milligrams of a plurality of vitamins, 24 grams of amino acid, 7 grams of artificial salt, 0.6 gram of aureomycin and 18 kilograms of silicon dioxide. The invention discloses the feed additive for the cadpigs.
Description
Technical field:
What the present invention relates to is a kind of feed addictive, feeding a kind of additive of specifically a kind of promotion cad pig (namely being caused the piglet of hypoevolutism or stagnation by many reasons) growth.The invention still further relates to the preparation method of this feed addictive.
Background technology:
It is the important component part in animal husbandry field that live pig produces, and pork also is one of China's traditional food, and according to statistics, pork accounts for more than 70% of consumption of meat.The development pig industry is conducive to the development of China people growth in the living standard and whole people's fitness.Piglet is in growth and development process, because a variety of causes (such as factors such as feed nutrition, diseases) causes the slow or stagnation behavior of Piglet Development, so-called cad pig has appearred, this boar is small and weak, staple length and coarse, and matt, indivedual pigs also are prone to symptom of digestive tract or respiratory symptom, and other various diseases of easy infection, causing the reinforcement of pathogen virulence and threaten other healthy pigs, is a large potential safety hazard of plant.In the scale pig farm, cad pig often occurs, and accounts for 5-7% on the northern area of China scale pig farm.Reinforcement is separated deadlock to the analysis of cad pig occurrence cause to cad pig, strengthens the feeding and management to cad pig, promotes it to grow, and to reducing the generation of disease, shortens and fattens the cycle, and it is significant to improve the pig farm economic benefit.
At present, how scientific worker and pig farm manager start with to promote growing of cad pig from many aspects both at home and abroad, as strengthening sow feeding management, promote galactosis; Reasonably combined feed formula guarantees the pig comprehensive nutrition; Strengthen young baby's swine rearing management, improve feed supplement, promote ontogeny; To the young baby pig of hypoevolutism or stagnation occurring, many isolated rearings, and suitably have additional nutrients, above measure is played positive role to growing of cad pig.But reason appears in the multianalysis cad pig, proposes solution, finds the technology with obvious curative effects, and relevant report is not yet arranged.
Also there are serious problems on the market now, a variety of Chinese herb feed additives all are that raw material is simply detected, screens, the active constituent content of this additive is unstable, even real very low to the useful component content of the growth of cad pig, and solution is stiff, gaining effect is not remarkable.So, more need to have the Chinese herbal medicine composite growth-promoting additive of high purity effective component on the market.
Summary of the invention:
The object of the invention is to for above-mentioned series of problems, by Chinese herbology, the traditional Chinese medical science, traditional Chinese veterinary medicine, pig disease are learned, the area researches such as pig nutrition and feed, the reason that the multianalysis cad pig produces, according to cad pig growth-development law and nutritional need, in conjunction with the mechanism of action of Chinese herbal medicine, a kind of higher cad pig Chinese herbal medicine composite growth-promoting additive of effective composition that contains is proposed.
Above-mentioned purpose realizes by following technical scheme:
The composite Chinese herbal additive of short cad pig growth, its composition comprises: the Radix Astragali, Radix Codonopsis, the Chinese bulbul, malt flour, garlic, Radix Glycyrrhizae, felwort, trace element, multivitamin, amino acid, artificial salt, aureomycin, silica, its parts by weight are: 6 kilograms of the Radixs Astragali, 2 kilograms of Radix Codonopsis, 2 kilograms of the Chinese bulbuls, 1 kilogram of malt flour, 2 kilograms in garlic, 4 kilograms in Radix Glycyrrhizae, 3 kilograms of felworts, 380.54 milligrams of trace elements, 287 milligrams of multivitamins, amino acid 24 grams, artificial salt 7 grams, aureomycin 0.6 gram, silica 1 8kg.
The composite Chinese herbal additive of described short cad pig growth, described trace element comprises: seven brochanites, white vitriol, Manganese sulfate pentahydrate, five water ferric sulfate, Sodium selenite (Na2SeO3) pentahydrate, KI, its parts by weight are: seven brochanite 50mg, white vitriol 110mg, Manganese sulfate pentahydrate 120mg, five water ferric sulfate 100mg, Sodium selenite (Na2SeO3) pentahydrate 0.40mg, KI 0.14mg.
The composite Chinese herbal additive of described short cad pig growth, described multivitamin comprises: vitamin A, vitamin B1, vitamin B2, vitamin C, cholecalciferol, vitamin E, vitamin K, its parts by weight are: vitamin A 15mg, vitamin B1 5mg, vitamin B2 8mg, vitamin C 250mg, cholecalciferol 5mg, vitamin E 3mg, vitamin K 1mg.
The composite Chinese herbal additive of described short cad pig growth, described amino acid comprises: lysine, methionine, its parts by weight are: lysine 18g, methionine 6g.
The preparation method of the composite Chinese herbal additive of above-mentioned short cad pig growth, the method comprises the steps: to extract Radix Codonopsis, the Chinese bulbul, garlic, Radix Glycyrrhizae, active ingredient in the felwort five tastes Chinese herbal medicine, add according to the above ratio the Radix Astragali, malt flour, trace element, multivitamin, amino acid, artificial salt, aureomycin evenly mixes, adopt the melting cooling method, with this blending constituent by 1: the weight ratio of 0.6-0.8 is adsorbed on the powder carrier material silica coated, coated temperature is 75 ℃, capsule core material accounts for micro-capsule 35%-45%, the wall material accounts for micro-capsule 55%-65%, after mixing, be cooled to room temperature, pulverize and make granularity at 80-100 purpose additive microcapsule powder.
The preparation method of the composite Chinese herbal additive of described short cad pig growth, the technical process of the active ingredient in the described extraction Radix Codonopsis is:
(1) dedusting is cleaned: the raw material Radix Codonopsis is removed impurity and the medicine that goes mouldy, the clear water flushing;
(2) chopping: the section that Radix Codonopsis is cut into 1-3cm;
(3) decoct: with the Radix Codonopsis section that cuts, put into to boil and propose the cylinder decoction, add pure water 10-11 doubly, decoct 3-4 time, each 3-4 hour, filter, merging filtrate, filter residue is abandoned it;
(4) concentrated: the filtrate decompression of merging is concentrated into semifluid, and proportion is 1.24-1.25, and temperature is 65-75 ℃, places cooling;
(5) centrifugation: the concentrate that will place cooling, centrifugation gets sediment and mother liquor, sediment is processed through following method: sediment is washed three times with pure water, add pure water by the 1/2-1/3 of sediment weight in wet base at every turn, stir evenly, centrifugation, in 55-65 ℃ of drying, getting yellow powder shape sediment is Radix Codonopsis polysaccharide extract;
(6) mother liquid disposal: merge three times separating obtained mother liquor, concentrated proportion is 1.24-1.25, and temperature is at 65-75 ℃.
The preparation method of the composite Chinese herbal additive of described short cad pig growth, the technical process of the active ingredient in the described extraction Chinese bulbul is: get 2 kilograms of the Chinese bulbuls, be ground into meal, divide inferior in the cable type extractor according, with the aether backflow degreasing, medicinal powder after the degreasing dries, ethanol 10L with 95% backflow 6-7 hour, filters while hot, the dregs of a decoction wash 2-3 time with the ethanol of 5L 95%, merging filtrate is evaporated to 0.5-0.6L, adds 1.8L acetone, namely separate out white opaque, make again in its ethanol that is dissolved in 1.4L70 ℃ 95%, filter, filtrate is splashed in the mixed solvent of acetone and ether, acetone: ether is 1.5: 1, adularescent opaque Precipitation is processed 2-3 time repeatedly, the white opaque of filter collection, in 70-80 ℃ of vacuum drying drying, get total saponins of pulsatilla chinensis.
The preparation method of the composite Chinese herbal additive of described short cad pig growth, the technical process of the active ingredient in the described extraction garlic is: garlic peeling is cleaned up, smash into mashed garlic, with after the steam deodorizing mashed garlic being incubated after 100 ℃ of Water Unders boil; The gained mixed liquor, high speed centrifugation, film ultrafiltration concentration, the ammoniacal liquor with pH=8.2 adds CaCl
2Solution stirs, again high speed centrifugation; The gained clear liquid, drying gets garlic polysaccharide (APS) white powder.
The preparation method of the composite Chinese herbal additive of described short cad pig growth, the technical process of the active ingredient in the described extraction Radix Glycyrrhizae is:
(1) pulverizes: clean dry Radix Glycyrrhizae is put into pulverizer pulverize, cross 20 mesh sieves, make licorice powder;
(2) extract: the licorice powder that makes is put into reactor, add the water of 5-6 times of quality of licorice powder, stir, 90 ℃ add hot reflux 2h, filter, and the water that filter residue adds 2 times of quality again repeats to extract once merging filtrate;
(3) concentrated: as above-mentioned filtrate to be carried out Vacuum Concentration with thin film evaporator, when filtrate volume reduces 3/4, filter while hot;
(4) separate: in the concentrated filtrate that has cooled off, add 95% ethanol of its 2/3 capacity, then leave standstill 12h, remove after filtration sediment;
(5) precipitation: in the glycyrrhizic acid concentrate of above-mentioned processing, regulate its pH value with hydrochloric acid, make the glycyrrhizic acid Precipitation, then carry out centrifugation, get thick glycyrrhizic acid;
(6) recrystallization: the 10-20% ethanol of thick glycyrrhizic acid with 65-75 ℃ is recrystallized, gets the wet product of glycyrrhizic acid behind the filtration under diminished pressure;
(7) drying: the glycyrrhizic acid that will wet is put into vacuum drying chamber, regulates vacuum, heats 60-70min under 60-70 ℃ of temperature, namely gets dried glycyrrhizic acid;
(8) finished product: the glycyrrhizic acid of drying is pulverized, and 40 orders that sieve get the glycyrrhizic acid finished product;
The preparation method of the composite Chinese herbal additive of described short cad pig growth, the technical process of the active ingredient in the described extraction felwort is: with the acetone of felwort with 75% concentration, leaching time is 24h, and the solvent consumption is 12 times of medicinal material, extraction time 4 times.
Beneficial effect of the present invention:
1. the cad pig Chinese herbal medicine composite growth-promoting additive finished product that makes of method of the present invention after testing, all technical is: polysaccharide content (weight ratio) 〉=9.21%, glycoside content (weight ratio) 〉=6.23%, flavonoids (weight ratio) 〉=1.66%, phenolic compound (weight ratio) 〉=2.27%, moisture (weight ratio)≤11.0%, finished product are lark or brown color powder.
Animal experiment 1:2008 carries out prolonged and repeated test on a number of pig farms of Heilongjiang Province's Anda City year October in June to 2009, and test group is for adding additive of the present invention, and control group does not add.160 of selective test group, solution is stiff, gaining effect is obvious, and the pig state of mind is good, and hair color recovers, and the morbidity pig is few, amounts to dead 9; 120 of control groups, 52 examples of falling ill amount to dead 30, and treatment cost amounts to 430 yuan.
Contemporaneity carries out prolonged and repeated test on a number of pig farms, Liaoyuan, Jilin province city, and test group is for adding additive of the present invention, and control group does not add.150 of test group, solution is stiff, gaining effect is remarkable, and the pig state of mind is good, and hair color recovers, and substantially without the morbidity pig, amounts to dead 7; 110 of control groups, 43 examples of falling ill amount to dead 26, and treatment cost amounts to 520 yuan.
Animal experiment 2: select parity, body weight, the basically identical cad pig of health status, namely control group and test group are established 10 repetitions for every group, and each repeats 10 pigs, and experimental period 30d detects the accumulation of Cu, Zn in the body tissue and the excretion in the ight soil.
Control group and test group basal diet are identical, energy level is (14.6MJ/Kg), protein level is (18%), wherein, control group is not for adding the daily ration of additive of the present invention, test group is for adding the daily ration of additive of the present invention, and adding proportion is 0.5% of basal diet, and test data is Epidemiological Analysis by statistics.
(1) accumulation of Cu and the excretion in the ight soil are in the test group body tissue: liver (3.09 ± 0.15) mg/kg, spleen (0.69 ± 0.03) mg/kg, kidney (3.30 ± 0.39) mg/kg, muscle (0.58 ± 0.09) mg/kg, ight soil (38.96 ± 5.13) mg/kg.The accumulation of Cu and excretion liver (3.09 ± 0.15) mg/kg in the ight soil, spleen (0.69 ± 0.03) mg/kg, kidney (3.30 ± 0.39) mg/kg, muscle (0.58 ± 0.09) mg/kg, ight soil (38.96 ± 5.13) mg/kg in the control group body tissue.
(2) accumulation of Zn and the excretion in the ight soil are in the test group body tissue: liver (29.15 ± 5.18) mg/kg, spleen (9.56 ± 0.65) mg/kg, kidney (12.96 ± 1.72) mg/kg, muscle (3.76 ± 0.31) mg/kg, ight soil (92.07 ± 9.73) mg/kg.The accumulation of Zn and the excretion in the ight soil are in the control group body tissue: liver (87.56 ± 0.59) mg/kg, spleen (16.83 ± 1.88) mg/kg, kidney (25.46 ± 2.89) mg/kg, muscle (5.97 ± 0.39) mg/kg, ight soil (133.12 ± 39.58) mg/kg.
Prove that through prolonged and repeated animal experiment the present invention is remarkable to the cad pig gaining effect, the pig state of mind is good, hair color recovers, and the morbidity pig is few, greatly reduces the death rate, can save by the cad pig rear medical expense that produces that catches, and can not pollute environment.
2. raw material wide material sources of the present invention, cheap, operating procedure is easy, drops into as feed addictive in cad pig and feeds, separate stiff, growth-promoting effect is remarkable; To play an important role to improving the pig farm economic benefit; This additive good stability, safe and efficient, drug residue free have a good application prospect and practical value.
The specific embodiment:
Embodiment 1:
The preparation method of the composite Chinese herbal additive of short cad pig growth, the method comprises the steps: to extract Radix Codonopsis, the Chinese bulbul, garlic, Radix Glycyrrhizae, active ingredient in the felwort five tastes Chinese herbal medicine, press 6 kilograms of the Radixs Astragali, 2 kilograms of Radix Codonopsis, 2 kilograms of the Chinese bulbuls, 1 kilogram of malt flour, 2 kilograms in garlic, 4 kilograms in Radix Glycyrrhizae, 3 kilograms of felworts, seven brochanite 50mg, white vitriol 110mg, Manganese sulfate pentahydrate 120mg, five water ferric sulfate 100mg, Sodium selenite (Na2SeO3) pentahydrate 0.40mg, KI 0.14mg, vitamin A 15mg, vitamin B1 5mg, vitamin B2 8mg, vitamin C 250mg, cholecalciferol 5mg, vitamin E 3mg, vitamin K 1mg, lysine 18g, methionine 6g, salt 7 grams, the ratio of aureomycin 0.6 gram is evenly mixed each component, adopt the melting cooling method, be adsorbed on the powder carrier material silica this blending constituent coated, silica consumption 18kg, coated temperature is 75 ℃, capsule core material accounts for micro-capsule 35%-45%, the wall material accounts for micro-capsule 55%-65%, after mixing, be cooled to room temperature, pulverize and make granularity at 80-100 purpose additive microcapsule powder.
Embodiment 2:
The preparation method of the composite Chinese herbal additive of above-mentioned short cad pig growth, the technical process of the active ingredient in the described extraction Radix Codonopsis is:
(1) dedusting is cleaned: the raw material Radix Codonopsis is removed impurity and the medicine that goes mouldy, the clear water flushing;
(2) chopping: the section that Radix Codonopsis is cut into 1-3cm;
(3) decoct: with the Radix Codonopsis section that cuts, put into to boil and propose the cylinder decoction, add pure water 10-11 doubly, decoct 3-4 time, each 3-4 hour, filter, merging filtrate, filter residue is abandoned it;
(4) concentrated: the filtrate decompression of merging is concentrated into semifluid, and proportion is 1.24-1.25, and temperature is 65-75 ℃, places cooling;
(5) centrifugation: the concentrate that will place cooling, centrifugation gets sediment and mother liquor, sediment is processed through following method: sediment is washed three times with pure water, add pure water by the 1/2-1/3 of sediment weight in wet base at every turn, stir evenly, centrifugation, in 55-65 ℃ of drying, getting yellow powder shape sediment is Radix Codonopsis polysaccharide extract;
(6) mother liquid disposal: merge three times separating obtained mother liquor, concentrated proportion is 1.24-1.25, and temperature is at 65-75 ℃.
Embodiment 3:
The preparation method of the composite Chinese herbal additive of above-mentioned short cad pig growth, the technical process of the active ingredient in the described extraction Chinese bulbul is: get 2 kilograms of the Chinese bulbuls, be ground into meal, divide inferior in the cable type extractor according, with the aether backflow degreasing, medicinal powder after the degreasing dries, ethanol 10L with 95% backflow 6-7 hour, filters while hot, the dregs of a decoction wash 2-3 time with the ethanol of 5L 95%, merging filtrate is evaporated to 0.5-0.6L, adds 1.8L acetone, namely separate out white opaque, make again in its ethanol that is dissolved in 1.4L70 ℃ 95%, filter, filtrate is splashed in the mixed solvent of acetone and ether, acetone: ether is 1.5: 1, adularescent opaque Precipitation is processed 2-3 time repeatedly, the white opaque of filter collection, in 70-80 ℃ of vacuum drying drying, get total saponins of pulsatilla chinensis.
Embodiment 4:
The preparation method of the composite Chinese herbal additive of above-mentioned short cad pig growth, the technical process of the active ingredient in the described extraction garlic is: garlic peeling is cleaned up, smash into mashed garlic, with after the steam deodorizing mashed garlic being incubated after 100 ℃ of Water Unders boil; The gained mixed liquor, high speed centrifugation, film ultrafiltration concentration, the ammoniacal liquor with pH=8.2 adds CaCl
2Solution stirs, again high speed centrifugation; The gained clear liquid, drying gets garlic polysaccharide (APS) white powder.
Embodiment 5:
The preparation method of the composite Chinese herbal additive of above-mentioned short cad pig growth, the technical process of the active ingredient in the described extraction Radix Glycyrrhizae is:
(1) pulverizes: clean dry Radix Glycyrrhizae is put into pulverizer pulverize, cross 20 mesh sieves, make licorice powder;
(2) extract: the licorice powder that makes is put into reactor, add the water of 5-6 times of quality of licorice powder, stir, 90 ℃ add hot reflux 2h, filter, and the water that filter residue adds 2 times of quality again repeats to extract once merging filtrate;
(3) concentrated: as above-mentioned filtrate to be carried out Vacuum Concentration with thin film evaporator, when filtrate volume reduces 3/4, filter while hot;
(4) separate: in the concentrated filtrate that has cooled off, add 95% ethanol of its 2/3 capacity, then leave standstill 12h, remove after filtration sediment;
(5) precipitation: in the glycyrrhizic acid concentrate of above-mentioned processing, regulate its pH value with hydrochloric acid, make the glycyrrhizic acid Precipitation, then carry out centrifugation, get thick glycyrrhizic acid;
(6) recrystallization: the 10-20% ethanol of thick glycyrrhizic acid with 65-75 ℃ is recrystallized, gets the wet product of glycyrrhizic acid behind the filtration under diminished pressure;
(7) drying: the glycyrrhizic acid that will wet is put into vacuum drying chamber, regulates vacuum, heats 60-70min under 60-70 ℃ of temperature, namely gets dried glycyrrhizic acid;
(8) finished product: the glycyrrhizic acid of drying is pulverized, and 40 orders that sieve get the glycyrrhizic acid finished product;
Embodiment 6:
The preparation method of the composite Chinese herbal additive of above-mentioned short cad pig growth, the technical process of the active ingredient in the described extraction felwort is: with the acetone of felwort with 75% concentration, leaching time is 24h, and the solvent consumption is 12 times of medicinal material, extraction time 4 times.
Using method: the additive microcapsule powder that makes is added feed in the solar eclipse of cad pig to getting final product to cad pig by 0.5% adding proportion of basal diet.
Claims (1)
1. the composite Chinese herbal additive of a short cad pig growth, its raw material forms and comprises: the Radix Astragali, Radix Codonopsis, the Chinese bulbul, malt flour, garlic, Radix Glycyrrhizae, felwort, trace element, multivitamin, amino acid, artificial salt, aureomycin, silica is characterized in that: its parts by weight are: 6 kilograms of the Radixs Astragali, 2 kilograms of Radix Codonopsis, 2 kilograms of the Chinese bulbuls, 1 kilogram of malt flour, 2 kilograms in garlic, 4 kilograms in Radix Glycyrrhizae, 3 kilograms of felworts, 380.54 milligrams of trace elements, 287 milligrams of multivitamins, amino acid 24 grams, artificial salt 7 grams, aureomycin 0.6 gram, silica 1 8kg; Wherein,
Described trace element comprises: seven brochanites, white vitriol, Manganese sulfate pentahydrate, five water ferric sulfate, Sodium selenite (Na2SeO3) pentahydrate, KI, and its parts by weight are: seven brochanite 50mg, white vitriol 110mg, Manganese sulfate pentahydrate 120mg, five water ferric sulfate 100mg, Sodium selenite (Na2SeO3) pentahydrate 0.40mg, KI 0.14mg;
Described multivitamin comprises: vitamin A, Cobastab
1, Cobastab
2, vitamin C, vitamin D
3, vitamin E, vitamin K, its parts by weight are: vitamin A 15mg, Cobastab
15mg, Cobastab
28mg, vitamin C 250mg, vitamin D
35mg, vitamin E 3mg, vitamin K 1mg;
Described amino acid comprises: lysine, methionine, and its parts by weight are: lysine 18g, methionine 6g;
The method for preparing the composite Chinese herbal additive of described short cad pig growth comprises the steps: to extract Radix Codonopsis, the Chinese bulbul, garlic, Radix Glycyrrhizae, active ingredient in the felwort five tastes Chinese herbal medicine, add according to the above ratio the Radix Astragali, malt flour, trace element, multivitamin, amino acid, artificial salt, aureomycin evenly mixes, adopt the melting cooling method, with this blending constituent by 1: the weight ratio of 0.6---0.8 is adsorbed on the powder carrier material silica coated, coated temperature is 75 ℃, capsule core material accounts for micro-capsule 35%--45%, the wall material accounts for micro-capsule 55%--65%, after mixing, be cooled to room temperature, pulverize and make granularity at 80---100 purpose additive microcapsule powder; Wherein,
The technical process of the active ingredient in the described extraction Radix Codonopsis is:
(1) dedusting is cleaned: the raw material Radix Codonopsis is removed impurity and the medicine that goes mouldy, the clear water flushing;
(2) chopping: with Radix Codonopsis be cut into 1-3cm the section,
(3) decoct: with the Radix Codonopsis section that cuts, put into to boil and propose the cylinder decoction, add pure water 10-11 doubly, decoct 3-4 time, each 3-4 hour, filter, merging filtrate, filter residue is abandoned it,
(4) concentrated: the filtrate decompression of merging is concentrated into semifluid, and proportion is 1.24---1.25, and temperature is 65--75 ℃, places cooling,
(5) centrifugation: the concentrate that will place cooling, centrifugation gets sediment and mother liquor, sediment is processed through following method: sediment is washed three times with pure water, add pure water by the 1/2-1/3 of sediment weight in wet base at every turn, stir evenly, centrifugation is in 55--65 ℃ of drying, getting yellow powder shape sediment is Radix Codonopsis polysaccharide extract
(6) mother liquid disposal: merge three times separating obtained mother liquor, concentrated proportion is 1.24-1.25, and temperature is at 65--75 ℃;
The technical process of the active ingredient in the described extraction Chinese bulbul is: get 2 kilograms of the Chinese bulbuls, be ground into meal, divide inferior in the cable type extractor according, with the aether backflow degreasing, the medicinal powder after the degreasing dries, the ethanol 10L with 95%, backflow 6-7 hour, filter while hot dregs of a decoction 5L
95% ethanol washing 2-3 time, merging filtrate is evaporated to 0.5-0.6L, add 1.8L acetone, namely separate out white opaque, make again in its ethanol that is dissolved in 70 ℃ 95% of 1.4L, filter, filtrate is splashed in the mixed solvent of acetone and ether acetone: ether is 1.5: 1, adularescent opaque Precipitation, repeatedly process 2-3 time, the white opaque of filter collection in 70--80 ℃ of vacuum drying, gets total saponins of pulsatilla chinensis;
The technical process of the active ingredient in the described extraction garlic is: garlic peeling is cleaned up, smash into mashed garlic, with after the steam deodorizing mashed garlic being incubated after 100 ℃ of Water Unders boil; The gained mixed liquor, high speed centrifugation, film ultrafiltration concentration, the ammoniacal liquor with pH=8.2 adds CaCl
2Solution stirs, again high speed centrifugation; The gained clear liquid, drying gets the garlic polysaccharide white powder;
The technical process of the active ingredient in the described extraction Radix Glycyrrhizae is:
(1) pulverize: clean dry Radix Glycyrrhizae is put into pulverizer pulverize, cross 20 mesh sieves, make licorice powder,
(2) extract: the licorice powder that makes is put into reactor, add the water of 5-6 times of quality of licorice powder, stir, 90 ℃ add hot reflux 2h, filter, and the water that filter residue adds 2 times of quality again repeats to extract once, merging filtrate,
(3) concentrated: above-mentioned filtrate is carried out Vacuum Concentration with thin film evaporator, when filtrate volume reduces 3/4, filter while hot,
(4) separate: in the concentrated filtrate that has cooled off, add 95% ethanol of its 2/3 capacity, then leave standstill 12h, remove after filtration sediment,
(5) precipitation: in the glycyrrhizic acid concentrate of above-mentioned processing, regulate its pH value with hydrochloric acid, make the glycyrrhizic acid Precipitation, then carry out centrifugation, get thick glycyrrhizic acid,
(6) recrystallization: the 10-20% ethanol of thick glycyrrhizic acid with 65--75 ℃ is recrystallized, gets the wet product of glycyrrhizic acid behind the filtration under diminished pressure,
(7) drying: the glycyrrhizic acid that will wet is put into vacuum drying chamber, regulates vacuum, heats 60-70min under 60--70 ℃ of temperature, namely gets dried glycyrrhizic acid,
(8) finished product: the glycyrrhizic acid of drying is pulverized, and 40 orders that sieve get the glycyrrhizic acid finished product;
The technical process of the active ingredient in the described extraction felwort is: with the acetone of felwort with 75% concentration, leaching time is 24h, and the solvent consumption is 12 times of medicinal material, extraction time 4 times.
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| CN105663454A (en) * | 2014-11-21 | 2016-06-15 | 青岛加云华海健康科技有限公司 | Traditional medicine composition, preparation thereof, and preparation method and application thereof |
| CN106721047A (en) * | 2016-11-25 | 2017-05-31 | 南宁学院 | A kind of method that edible fungi leftovers prepare multifunctional feed |
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| CN106578452A (en) * | 2016-11-25 | 2017-04-26 | 南宁学院 | Herbivorous animal feed made from grape branches |
| CN106721061A (en) * | 2016-11-25 | 2017-05-31 | 南宁学院 | A kind of growth promoter for animal |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1275393A (en) * | 1999-05-28 | 2000-12-06 | 中国科学院黑龙江农业现代化研究所 | Chinese medicinal herbs composite growth-promoting additives for runt pig |
| CN1561792A (en) * | 2004-04-16 | 2005-01-12 | 中国农业科学院饲料研究所 | Method for preparing common origanum herb oil micro capsule powder for natural fodder germicide |
| CN1733050A (en) * | 2005-08-27 | 2006-02-15 | 叶美曾 | Asiabell polysaccharide tablet of asiabell effective ingredient |
-
2009
- 2009-12-11 CN CN2009100733957A patent/CN102090506B/en active Active
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1275393A (en) * | 1999-05-28 | 2000-12-06 | 中国科学院黑龙江农业现代化研究所 | Chinese medicinal herbs composite growth-promoting additives for runt pig |
| CN1561792A (en) * | 2004-04-16 | 2005-01-12 | 中国农业科学院饲料研究所 | Method for preparing common origanum herb oil micro capsule powder for natural fodder germicide |
| CN1733050A (en) * | 2005-08-27 | 2006-02-15 | 叶美曾 | Asiabell polysaccharide tablet of asiabell effective ingredient |
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