CN102087136B - Tablet weight detecting method based on radiation acoustic field of die - Google Patents
Tablet weight detecting method based on radiation acoustic field of die Download PDFInfo
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- CN102087136B CN102087136B CN2010105549445A CN201010554944A CN102087136B CN 102087136 B CN102087136 B CN 102087136B CN 2010105549445 A CN2010105549445 A CN 2010105549445A CN 201010554944 A CN201010554944 A CN 201010554944A CN 102087136 B CN102087136 B CN 102087136B
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- punch die
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- tablet weight
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B30—PRESSES
- B30B—PRESSES IN GENERAL
- B30B11/00—Presses specially adapted for forming shaped articles from material in particulate or plastic state, e.g. briquetting presses, tabletting presses
- B30B11/02—Presses specially adapted for forming shaped articles from material in particulate or plastic state, e.g. briquetting presses, tabletting presses using a ram exerting pressure on the material in a moulding space
- B30B11/08—Presses specially adapted for forming shaped articles from material in particulate or plastic state, e.g. briquetting presses, tabletting presses using a ram exerting pressure on the material in a moulding space co-operating with moulds carried by a turntable
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Abstract
The invention provides a tablet weight detecting method based on a radiation acoustic field of a die, belonging to the tablet weight automatic control system of medicament preparation equipment. In the method, a low-frequency vibration displacement equation and a vibration speed of a die are analyzed based on the boundary condition and initial condition of vibration so as to calculate an acoustic pressure equation of the radiation acoustic field of the die; the relationship between the tablet weight and main pressure is analyzed, a basis for detecting tablet weight difference is given according to the main pressure so as to derive a basic equation for detecting the tablet weight difference based on the radiation acoustic field caused by die vibration, and a control standard for judging the tablet weight difference is given according to the acoustic pressure based on the radiation acoustic field caused by the die vibration; and the tablet weight is detected based on the radiation acoustic field of the die according to the control standard which judges the tablet weight difference based on the acoustic pressure. The method has the advantages that the tablet weight is detected by utilizing the radiation acoustic field of the die, and inspectors need not come to the production field when the method is utilized; and the pollution to the tablets is reduced, so the method is an effective method for detecting the tablet weight difference.
Description
Technical field
The present invention relates to a kind of heavy automatic control system of sheet of pharmaceutical preparation equipment, particularly a kind of based on the heavy method of the radiated sound field detection lug of punch die.
Background technology
The detection method of high speed rotating sheeter mainly contains: the non-linear monitoring method of principal pressure deviation, the gray prediction detection method that sheet is heavy.
The non-linear monitoring method of principal pressure deviation is in the compressing tablet process, controlling tablet weight in real time, being pressed into nib through the measurement drift and making power suffered in the filler compression process come indirect control strip heavy.Computing machine constantly detects drift pressure transducer numerical value, and according to data processed result, control executing mechanism is regulated loading according to certain rules, in real time sheet is heavily controlled, is adjusted.
The gray prediction detection method that sheet is heavy is a forecast Control Algorithm; Be exactly in each sampling instant; The mathematical model of the behavioral characteristics of the data sequence descriptive system of being sampled according to controlled system present stage; A series of system output in the future certain limit is predicted that the system's output that predicts the outcome thus then and provide is controlled system implementation by certain algorithm.This kind method of inspection mainly is to take sampling to carry out at present, and used equipment mainly is the very high weigh scale of precision.
Insert the drug particles of nib constantly in difference, density, difference such as homogeneity are bigger, and for different drug medicinal powder, this difference is more obvious, and from the heavy deviation of sheet occurring to the process of regulating loading again, is arranged one period long retardation time.Hand over when this, the system of retardation is arranged, the control that follows conventional lines often can not get the control effect of being satisfied with.The gray prediction detection method has overcome the influence of time lag to a certain extent, has improved control accuracy.But the gray prediction detection method is a kind of direct detecting method, needs the on-the-spot regularly detection of operating personnel and supervisory personnel, increases the tablet degree of polluting.The non-linear detection method of principal pressure deviation; Improved the timeliness that sheet is heavily controlled, but since it be with the pressure divergence of typical medicinal powder with fill the control law that depth curve forms, often because of the density of particle; Factor effect meetings such as homogeneity bring error bigger, and useless sheet rate is higher.
Summary of the invention
The objective of the invention is to provide a kind of based on the heavy method of the radiated sound field detection lug of punch die, solve the non-linear detection method of principal pressure deviation, because of the density of particle, homogeneity factor error is bigger, and useless sheet rate is higher; And the gray prediction detection method increases the problem of polluting the tablet degree.
The objective of the invention is to realize like this: mainly contain three steps based on the heavy method of the radiated sound field detection lug of punch die:
Step 1: calculate punch die and bear periodically acting force;
The high speed rotating sheeter has different secondary punch dies, and every secondary punch die all repeats same compressed tablets process, and label and following punch die are formed the little amplitude compressional vibration of compound bar, calculates punch die and bears periodically acting force;
Non-contact testing is arranged with height such as sensor and tested die-punch, is kept certain spacing between the two; Sensor is contained on the stationary installation, is installed in together with stationary installation on the frame of high speed rotating sheeter;
(1) in the tablet manufacturing workshop, choose a high speed rotating sheeter, to choose and set up label and punch die composition compound bar stress model, start is produced, and by the time the steady production stage, the test compound rod bears principal pressure;
(2) transit time, dwell time and the transit time of a secondary punch die job in the test punch die course of work, calculate a secondary punch die work period;
(3), obtain the suffered external force complex representation of compound bar form by Fourier's therorem according to compound bar stressing conditions and working time situation;
Step 2: punch die vibration equation when obtaining high speed rotating sheeter master and pressing;
By the boundary condition and the starting condition of vibration, calculate each section low-frequency vibration displacement equation of obtaining compound bar and the equation of vibration velocity, the acoustic pressure equation of derivation punch die radiated sound field;
(1) according to the suffered external force complex representation of compound bar form, obtain the compressional vibration equation of compound bar, write out displacement and represent general formula;
(2) boundary condition and the starting condition of definite vibration;
(3) derive each section low-frequency vibration displacement equation of compound bar and the equation of vibration velocity, obtain the acoustic pressure equation of punch die radiated sound field;
Step 3: the acoustic pressure detection lug of punch die radiated sound field is heavy during according to main the pressure;
Relation between analytic plate weight and the principal pressure; Provide the foundation of judging tablet weight variation according to principal pressure; Derive the fundamental equation of the detection tablet weight variation of the radiated sound field that vibration causes based on punch die, the acoustic pressure that provides the radiated sound field that causes according to the vibration based on punch die is judged the control criterion of tablet weight variation;
Situation during (1) according to low frequency is used as piston acoustic source to the vibration of the upper section of label along axis direction, measures its radius, calculates the upper section vibration velocity of label;
(2) set up coordinate system, obtain the acoustic pressure equation of compound bar radiated sound field,, calculate sound pressure level according to parameter value;
(3) according to the heavy deviation of sheet, principal pressure deviation and acoustic pressure relation, derivation tablet weight variation control formula;
High speed rotating sheeter punch die when main the pressure can send rattle clocklike; There is deviation in every secondary punch die to the principal pressure that label applies when main the pressure; The amplitude of every secondary punch die is also inequality thus; The sound pressure level of the radiated sound field of punch die and loudness level are also inequality, utilize this characteristic can come the heavy difference of detection lug.
Beneficial effect owing to adopted such scheme, when high speed rotating sheeter master presses, receives periodically principal pressure effect to punch die, so the vibration of generating period property, and punch die produces sound field clocklike.By the boundary condition and the starting condition of vibration, analyze the low-frequency vibration displacement equation and the vibration velocity of punch die, obtain the acoustic pressure equation of punch die radiated sound field.Relation between analytic plate weight and the principal pressure; Provide the foundation of judging tablet weight variation according to principal pressure; Derive the fundamental equation of the detection tablet weight variation of the radiated sound field that vibration causes based on punch die, the acoustic pressure that provides the radiated sound field that causes according to the vibration based on punch die is judged the control criterion of tablet weight variation.Judge that according to acoustic pressure the control criterion of tablet weight variation realizes based on the heavy method of the radiated sound field detection lug of punch die.
Solved the non-linear detection method of principal pressure deviation, because of the density of particle, homogeneity factor error is bigger, and useless sheet rate is higher; And the problem of gray prediction detection method increase pollution tablet degree, reached the object of the invention.
Advantage: having realized utilizing the radiated sound field of punch die to come detection lug heavy, utilized this method supervisory personnel needn't appear at the production scene, reduced the pollution to tablet, is the heavy differences method of a kind of effective coupon.
Embodiment
Embodiment 1: mainly contain three steps based on the heavy method of the radiated sound field detection lug of punch die:
Step 1: calculate punch die and bear periodically acting force
(1) choose a high speed rotating sheeter in the tablet manufacturing workshop, choose and set up label and punch die composition compound bar stress model, start is produced, and by the time the steady production stage, the test compound rod bears principal pressure.
In the tablet manufacturing workshop, environment temperature is+25 ℃, and relative humidity is less than in 85% storage environment.During the work of high speed rotating sheeter punch die; The label of presuppression is led pressure at the drift that the descends punch die upper trimming die that main pinch roller is depressed on the quilt in middle nib; This situation is regarded the little amplitude compressional vibration of the label that receives the upper trimming die effect and the compound bar of following punch die as, and (following main pinch roller is fixed) fixed in this compound bar lower end.Compound bar by label and following punch die are formed can be divided into 3 sections.To following each section of punch die, three segments become 1,2 and 3 section respectively from top to bottom by label.1 section thickness is h
1, diameter is d
12 sections jumper bar length are l
2, diameter is F
23 segment length are l
3, diameter is F
3Start is produced, and by the time the steady production stage, the test compound rod bears the principal pressure situation.
(2) transit time, dwell time and the transit time of a secondary punch die job in the test punch die course of work, calculate a secondary punch die work period.
The compressing tablet process is made up of steps such as beginning pressurization, pressurize and decompress(ion)s.Main up and down pinch roller has just begun to contact with die-punch planar section up and down, runs to the final position to punch die up and down and is pressing time beginning; Punch die runs to the final position up and down, and main up and down pinch roller is the dwell time with the time that die-punch planar section up and down keeps in touch; Punch die runs to the final position and finishes up and down, begins to rise, and begins to separate to main pinch roller up and down and die-punch planar section up and down, is decompression time.When the composition of pressure and tablet was all identical, the dwell time was longer, and tablet strength exceedes greatly.The high speed rotating sheeter is designed to the sheeter of two steps compression in order to increase the dwell time.At first drug particles is carried out precompressed, lead pressure afterwards again.The position of the middle relatively mould of interior punch die bar of dwell time remains unchanged during main the pressure.The high speed rotating sheeter has different secondary punch dies, and every secondary punch die all repeats same tablet agent process;
Come and compound bar is said so and born periodically acting force for sheeter
F(
t).If be T the transit time of work
s, the dwell time is T
d, be T transit time
j, a punch die work period is T.Cycle and dwell time are:
Principal pressure
(
p=1,2,3 ..., N;
k=0,1,2 ...)
Wherein
Wherein, N is the punch die number of a high speed rotating sheeter; F
μBe the heavy average principal pressure value of the average sheet of correspondence; Δ F
pBe the principal pressure deviation.F
Min, F
MaxBe respectively the suffered principal pressure F of punch die
PMinimum value and maximal value.
(3) according to compound bar stressing conditions and working time situation, obtain compound bar by Fourier's therorem
Suffered external force complex representation form.
Accompanying drawing 2 is a power
F(
t) rectangle recurrent pulse form.
F(
t) can be expressed as
According to Fourier's therorem,
F(
t) can be expressed as
During as
; Because
is 0, so this moment, corresponding initial phase
did not need to discuss.
When
The time, have
(
m=1,2,3 ...)
Compound bar is stressed can be write as
Step 2: punch die vibration equation when obtaining high speed rotating sheeter master and pressing
(1) according to the suffered external force complex representation of compound bar form, obtain the compressional vibration equation of compound bar, write out displacement and represent general formula.
Set up the compressional vibration equation of compound bar:
In the formula:
cBe the compressional vibration velocity of propagation of compound bar,
Be the deformation of compound bar along the ordinate direction.Formula (1) separate for
In the formula:
Be wave number,
wBe angular frequency.
(2) boundary condition and the starting condition of definite vibration.
If the compound bar that each section of compound bar yang type modulus, density, the velocity of sound, length and xsect are constituted is respectively
,
,
,
and
; I=1; 2,3 representatives belong to each section of compound bar.Because down two sections of punch dies are made by same material, will keep the thickness of certain tablet in addition.
Then the displacement of each section does
（3）
Wherein
i=1,2,3, the of expression compound bar
iSection.
Suppose to get acting force
(
) act on rod, obtain relevant parameter
With
(wherein
i=1,2,3).When effect
power, each segment boundary condition of rod does
(3) derive each section low-frequency vibration displacement equation of compound bar and the equation of vibration velocity, obtain the acoustic pressure equation of punch die radiated sound field.
Because the 2nd is identical with the 3rd section material, therefore have:
.Be respectively from the 1st section to the 3rd section displacement
According to actual conditions,
,
,
,
With
(i=1,2,3) concrete value can be got
n3 sections vibration displacement value during=1 o'clock low frequency, and
n=1 o'clock their vibration velocity.
Step 3: the acoustic pressure detection lug of punch die radiated sound field is heavy during according to main the pressure
Sheeter comes punch die to bear periodically acting force, and the vibration of punch die generating period property produces radiated sound field, can obtain the acoustic pressure of punch die radiated sound field.Relation by sheet weight and principal pressure; Relation by principal pressure and vibration displacement; By the relation of vibration displacement and acoustic pressure, can obtain sheet at last and heavily and between the acoustic pressure concern, can access the fundamental equation of the detection tablet weight variation of the radiated sound field that vibration causes based on punch die then; The acoustic pressure that provides the radiated sound field that causes according to the vibration based on punch die is judged the control criterion of tablet weight variation, accurately rejects undesirable tablet in the production run.
Situation during (1) according to low frequency is used as piston acoustic source to the vibration of the upper section of label along axis direction, measures its radius, calculates the upper section vibration velocity of label.
When n=1 during low frequency, the vibration of the upper section of label is along axis direction, i.e. its normal direction vibration, and vibration amplitude of each point is all identical with phase place on it, can be used as piston acoustic source, and its radius is r
1, can obtain the upper section vibration velocity of label.Can obtain vibration velocity
by formula (5).
(2) set up coordinate system, obtain the acoustic pressure equation of compound bar radiated sound field,, calculate sound pressure level according to parameter value.
Getting kernel of section is true origin, and the plane at place, cross section is the yz plane, and axis is the x axle.Because sound field is rotational symmetric for the x axle that passes kernel of section, the observation point Q that establishes in the sound field that therefore is without loss of generality is located in the xz plane, and the distance that it leaves initial point is r, and the angle of position vector r and x axle is q.
Obtain the acoustic pressure equation:
In the formula:
wBe angular frequency;
r 0Be atmospheric density;
r 1Radius for the cross section;
kBe wave number; J
1(
Kr 1Sinq) be the post Bessel's function;
u aMaximum amplitude for vibration velocity.
(3) according to the heavy deviation of sheet, principal pressure deviation and acoustic pressure relation, derivation tablet weight variation control formula.
if
, then
.
Because
Kr 1Be far smaller than 1, the directional property formula in punch die cross section
By (6) formula, can get
At the actual principal pressure of steady production stage punch die do
F p With the actual sheet of punch die heavily do
Q p (wherein
pBe the numbering of punch die,
p=1,2,3 ..., N).There is nonlinear relationship between principal pressure and sheet are heavy.When detection lug is heavy automatically in the production, establish
F p With
Q p There is funtcional relationship
then has:
Again because
In the formula: D
Q p For tablet weight variation or be called the heavy error of sheet,
Q μ For average sheet weighs.
Make A
1=7.5%, A
2=5%, then have:
Constantly obtain principal pressure by (9) and change limit, establish
Relation is as shown in table 1 between heavy limit of average sheet and the principal pressure variation limit.
Table 1 parameter limit
According to table 1, the standard of tablet weight variation control does
In the formula:
expression sheet overlaps lattice;
expression sheet is heavy defective; For useless sheet, with disallowable.
High speed rotating sheeter punch die when work, the label of presuppression the drift of punch die down in middle nib by on main pinch roller depress the upper trimming die that comes and lead pressure, this situation is regarded the little amplitude compressional vibration of the label that receives the upper trimming die effect and the compound bar of following punch die as.Used acoustic emission detection instrument mainly is made up of the signal acquiring system that sensor, prime amplifier, PC I2II capture card and PC are formed.
Signal Processing adopts wavelet analysis method, can find out characteristic frequency through analyzing the punch die vibration, confirms according to the variation of these frequency components whether tablet weight variation exceeds the difference limit.The heavy satisfactory punch die acoustical signal of sheet is called noise signal or claims qualified signal, and the punch die signal of the heavy overrun of sheet is called useless sheet signal.
The PCI2 II double channel data acquisition card that experiment is adopted broadband sensor, 2/4/6 type prime amplifiers and produced by U.S. PAC company.Experiment parameter setting is seen table 2.
Table 2 acoustic emission parameter setting
Because the stress wave that the stress wave source produces could be received by sensor after will passing through the propagation of medium; And stress wave will produce decay in communication process; From consideration to reception; Non-contact testing arranges that with the height such as upper section grade of sensor and label keep certain spacing s (mm) between the two, s is between 100mm～800mm.Sensor is contained on the fixed mount, is installed in together with fixed mount on the frame of high speed rotating sheeter.
Claims (1)
1. one kind based on the heavy method of the radiated sound field detection lug of punch die, it is characterized in that: mainly contain three steps based on the heavy method of the radiated sound field detection lug of punch die:
Step 1: calculate punch die and bear periodically acting force;
The high speed rotating sheeter has different secondary punch dies, and every secondary punch die all repeats same compressed tablets process, and label and following punch die are formed the little amplitude compressional vibration of compound bar, calculates punch die and bears periodically acting force;
Non-contact testing is arranged with height such as sensor and tested die-punch, is kept certain spacing between the two; Sensor is contained on the stationary installation, is installed in together with stationary installation on the frame of high speed rotating sheeter;
(1) in the tablet manufacturing workshop, choose a high speed rotating sheeter, to choose and set up label and punch die composition compound bar stress model, start is produced, and by the time the steady production stage, the test compound rod bears principal pressure;
(2) transit time, dwell time and the transit time of a secondary punch die job in the test punch die course of work, calculate a secondary punch die work period;
(3), obtain the suffered external force complex representation of compound bar form by Fourier's therorem according to compound bar stressing conditions and working time situation;
Step 2: punch die vibration equation when obtaining high speed rotating sheeter master and pressing;
By the boundary condition and the starting condition of vibration, calculate each section low-frequency vibration displacement equation of obtaining compound bar and the equation of vibration velocity, the acoustic pressure equation of derivation punch die radiated sound field;
(1) according to the suffered external force complex representation of compound bar form, obtain the compressional vibration equation of compound bar, write out displacement and represent general formula;
(2) boundary condition and the starting condition of definite vibration;
(3) derive each section low-frequency vibration displacement equation of compound bar and the equation of vibration velocity, obtain the acoustic pressure equation of punch die radiated sound field;
Step 3: the acoustic pressure detection lug of punch die radiated sound field is heavy during according to main the pressure;
Relation between analytic plate weight and the principal pressure; Provide the foundation of judging tablet weight variation according to principal pressure; Derive the fundamental equation of the detection tablet weight variation of the radiated sound field that vibration causes based on punch die, the acoustic pressure that provides the radiated sound field that causes according to the vibration based on punch die is judged the control criterion of tablet weight variation;
Situation during (1) according to low frequency is used as piston acoustic source to the vibration of the upper section of label along axis direction, measures its radius, calculates the upper section vibration velocity of label;
(2) set up coordinate system, obtain the acoustic pressure equation of compound bar radiated sound field,, calculate sound pressure level according to parameter value;
(3) according to the heavy deviation of sheet, principal pressure deviation and acoustic pressure relation, derivation tablet weight variation control formula;
High speed rotating sheeter punch die when main the pressure can send rattle clocklike; There is deviation in every secondary punch die to the principal pressure that label applies when main the pressure; The amplitude of every secondary punch die is also inequality thus; The sound pressure level of the radiated sound field of punch die and loudness level are also inequality, utilize this characteristic can come the heavy difference of detection lug.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2010105549445A CN102087136B (en) | 2010-11-23 | 2010-11-23 | Tablet weight detecting method based on radiation acoustic field of die |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2010105549445A CN102087136B (en) | 2010-11-23 | 2010-11-23 | Tablet weight detecting method based on radiation acoustic field of die |
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| CN102087136B true CN102087136B (en) | 2012-07-04 |
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| CN107608729A (en) * | 2017-09-14 | 2018-01-19 | 光锐恒宇（北京）科技有限公司 | A kind of method and apparatus for showing dynamic effect in the application |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SU1525474A1 (en) * | 1987-11-30 | 1989-11-30 | Ленинградский Завод "Госметр" Ленинградского Производственного Объединения "Вибратор" | Method of determining rigidity of scale suspension unit |
-
2010
- 2010-11-23 CN CN2010105549445A patent/CN102087136B/en not_active Expired - Fee Related
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SU1525474A1 (en) * | 1987-11-30 | 1989-11-30 | Ленинградский Завод "Госметр" Ленинградского Производственного Объединения "Вибратор" | Method of determining rigidity of scale suspension unit |
Non-Patent Citations (1)
| Title |
|---|
| 徐安祥.冲床的振动与噪声.《机械工人.冷加工》.1995,(第08期), * |
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