CN102078366A - Hemsley rockvine root lozenge for diminishing inflammation and resisting viruses and preparation method thereof - Google Patents

Hemsley rockvine root lozenge for diminishing inflammation and resisting viruses and preparation method thereof Download PDF

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Publication number
CN102078366A
CN102078366A CN 201110006136 CN201110006136A CN102078366A CN 102078366 A CN102078366 A CN 102078366A CN 201110006136 CN201110006136 CN 201110006136 CN 201110006136 A CN201110006136 A CN 201110006136A CN 102078366 A CN102078366 A CN 102078366A
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radix
apioris fortunei
lespedezae buergeri
solution
lozenge
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CN102078366B (en
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杨军
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Abstract

The invention provides a hemsley rockvine root lozenge for diminishing inflammation and resisting viruses and a preparation method thereof. The preparation method provided by the invention can be used for preparing a lozenge which keeps the original nutrient substance components and has the functions of diminishing inflammation and resisting viruses. The advanced technology is used for deeply processing the hemsley rockvine root, i.e. the hemsley rockvine root is treated by the processes of cleaning, crushing, microwave extraction, enzymatic saccharification, secondary filtration, spray drying, granulating, tabletting and the like, thus the hemsley rockvine root fully exerts the medical properties in the preparation process, and the effective components of the hemsley rockvine root are furthest protected. The Chinese herbal medicine hemsley rockvine root is prepared into an oral lozenge which can be carried simply, saved easily and taken conveniently and has the functions of diminishing inflammation and resisting viruses. The high-concentration medical lozenge can sterilize the oral throat and can enter a human body, so that the hemsley rockvine root can exert the functions of resisting bacteria, diminishing inflammation, resisting viruses and improving immunity. By orally taking the hemsley rockvine root lozenge for diminishing inflammation and resisting viruses, the bacteria in the oral cavity can be effectively sterilized, and upper respiratory tract communicable diseases such as influenza and the like can be prevented.

Description

A kind of Radix Apioris Fortunei (Radix Lespedezae Buergeri) antiinflammatory antivirus buccal tablet and manufacture method
Technical field
The present invention relates to a kind of processing of Chinese herbal medicine, particularly utilize the Chinese herbal medicine Radix Apioris Fortunei (Radix Lespedezae Buergeri) to make the method for antiinflammatory antivirus buccal tablet, belong to the processing technique of Chinese herbs field.
Background technology
Be listed in the Radix Apioris Fortunei (Radix Lespedezae Buergeri) of rare plant in imminent danger, belong to the exclusive precious species of China, be grown in Zhejiang, Jiangxi, Fujian, part mountain area, Anhui usually.Radix Apioris Fortunei (Radix Lespedezae Buergeri) has magical medicinal efficacy, have effects such as the immunity of raising, antiviral, enhancing liver function, be described as the superfine product Chinese herbal medicine by Chinese medicine circle, especially hepatitis B, kinds of tumors, cancer, infantile hyperpyrexia convulsions, dysentery, bronchitis, pneumonia, pharyngolaryngitis, viral meningitis etc. had unique curative effect.Hyperpyrexia, hyperpyrexia convulsions, inflammatory edema, snakebite to unknown cause have unique curative effect, are Western medicine irreplaceable " bouvardins ", and economic worth is very high.
Radix Apioris Fortunei (Radix Lespedezae Buergeri), sweet in the mouth, cool in nature, plant name: Radix Tetrastigmatis Hemsleyani, be the root of vitaceae tetratigma hemsleyanum, have another name called the gold thread hoist.Contain chemical constituents such as flavonoid, steroidal class, phenols, organic acid, aminoacid, starch, polysaccharide.The quality of Radix Apioris Fortunei (Radix Lespedezae Buergeri) pharmaceutical quality does not lie in its size and is to select the suitable time of excavating, and that plucks during the annual Winter Solstice-Waking of Insects (3rd solar term) is best in quality, the Radix Apioris Fortunei (Radix Lespedezae Buergeri) tuber that pluck this moment, and content of starch is more than 70% after testing, and medicinal effects is best.
Summary of the invention
The invention provides a kind of processing that utilizes advanced technology to the Radix Apioris Fortunei (Radix Lespedezae Buergeri) profound level; produce and promptly kept original nutrient substance composition; the buccal tablet that has antiinflammatory antiviral function again; by Radix Apioris Fortunei (Radix Lespedezae Buergeri) is cleaned and crush, operations such as microwave extracting, enzymatic saccharification, secondary filter, spray drying, pelletize tabletting make; on the make give full play of the property of medicine of Radix Apioris Fortunei (Radix Lespedezae Buergeri), farthest protect the effective ingredient of Radix Apioris Fortunei (Radix Lespedezae Buergeri).Utilize the enzymatic saccharification of amylase to a large amount of starch in the Radix Apioris Fortunei (Radix Lespedezae Buergeri), solved the filtering problem of starch dissolution difficulty or ease in medicinal liquid in manufacturing process, the starch viscosity of gelatinizing descends rapidly behind the enzymolysis, hydrolysis is generated as maltose and the glucose that human body absorbs easily, promptly increased the cost that the sugariness in the buccal tablet reduces additive in the production again.
In manufacturing process, adopt microwave-assisted extraction technique, utilizing microwave moment to penetrate the material heating extracts, the Radix Apioris Fortunei (Radix Lespedezae Buergeri) effective ingredient spreads in extractant water under microwave irradiation effect, effective ingredient freely flows out in the cell, under lower temperature, be dissolved in the water, by further filtering and separating, obtain the efficient solution of Radix Apioris Fortunei (Radix Lespedezae Buergeri) of microwave extracting again.Microwave extracting has characteristics such as extraction efficiency height, purity is good, energy consumption is little, operating cost is low, and temperature does not surpass 60 ℃ in the entire making process, guarantees the effective ingredient and the quality of buccal tablet to greatest extent.
The Chinese herbal medicine Radix Apioris Fortunei (Radix Lespedezae Buergeri) is made into a kind of a kind of oral buccal tablet with antiinflammatory, antivirus action that carries simple, easy preservation, taking convenience, the medicine of high concentration can carry out sterilization to oral cavity and throat, enter and will bring into play in the human body that Radix Apioris Fortunei (Radix Lespedezae Buergeri) is antibiotic, the function of antiinflammatory, antiviral, raising immunity, buccal Radix Apioris Fortunei (Radix Lespedezae Buergeri) antiinflammatory antivirus buccal tablet, the antibacterial in the oral cavity can be killed effectively, the upper respiratory infectious diseases such as influenza can be prevented again.
The specific embodiment
1. excavate cleaning: during Winter Solstice-Waking of Insects (3rd solar term), excavate fresh Radix Apioris Fortunei (Radix Lespedezae Buergeri) tuber, water is rinsed well after removing the earth foreign material on the tuber, reuse germicidal solution 0.06% bleaching fluid soaks 2-5min, removes medicinal liquid on the tuber with flushing with clean water then, and spray is cleaned and drained.
2. broken immersion the: the Radix Apioris Fortunei (Radix Lespedezae Buergeri) that drains is become 3-4mm granule with crusher in crushing, granule in the Radix Apioris Fortunei (Radix Lespedezae Buergeri) after the fragmentation is put into the microwave extracting jar, the production of weight such as adding is soaked 1-2h with pure water, open the microwave extracting jar and use microwave frequency 2450MHz, extraction time 2-4min.
3. soak heating: the Radix Apioris Fortunei (Radix Lespedezae Buergeri) solution of microwave extracting is heated, and heating and temperature control is at 35-45 ℃, time 15-30min, and heating is beneficial to oozing out of effective ingredient.
4. enzymatic saccharification: decompose water soluble starch in the Radix Apioris Fortunei (Radix Lespedezae Buergeri) solution, amylase consumption 2-3g/100L, 28-33 ℃ of the temperature of amylase Treatment Solution, enzyme processing time 6-8h, the starch in the enzymolysis solution fully with a-amylase.
5. secondary filter: earlier with 100 mesh filter screen elimination medicinal residues, the reuse diatomite filter is crossed the fine particle thing in the elimination solution, helps the drying of spray dryer like this with the Radix Apioris Fortunei (Radix Lespedezae Buergeri) solution behind the amylorrhexis.
6. atomization drying: the Radix Apioris Fortunei (Radix Lespedezae Buergeri) solution after the filtration adopts the pressure type atomizing dryer to carry out drying, and the atomization drying temperature is controlled at 45-50 ℃, carries out the solution atomization drying under atomisation pressure 5000KPa.
7. pelletize tabletting: take by weighing Radix Apioris Fortunei (Radix Lespedezae Buergeri) xeraphium 40%, maltose 50%, aspartame 0.5%, sweet glycan 0.5%, citric acid 3%, malic acid 1%, vitamin C 1%, Mel 3% by weight proportion, mixed 80 mesh sieves, adding 95% ethanol mixes wet, granulate with 20 mesh sieves, behind 60 ℃ of hot air dryings, after adding magnesium stearate 1% abundant mix homogeneously again, carry out tabletting, quality inspection, packing making finished product 500mg~1000mg/ buccal tablet.

Claims (1)

1. Radix Apioris Fortunei (Radix Lespedezae Buergeri) antiinflammatory antivirus buccal tablet and manufacture method is characterized in that: made by following steps:
Excavate cleaning: during Winter Solstice-Waking of Insects (3rd solar term), excavate fresh Radix Apioris Fortunei (Radix Lespedezae Buergeri) tuber, water is rinsed well after removing the earth foreign material on the tuber, reuse germicidal solution 0.06% bleaching fluid soaks 2-5min, removes medicinal liquid on the tuber with flushing with clean water then, and spray is cleaned and drained;
The broken immersion: the Radix Apioris Fortunei (Radix Lespedezae Buergeri) that drains is become 3-4mm granule with crusher in crushing, granule in the Radix Apioris Fortunei (Radix Lespedezae Buergeri) after the fragmentation is put into the microwave extracting jar, the production of weight such as adding is soaked 1-2h with pure water, opens the microwave extracting jar and uses microwave frequency 2450MHz, extraction time 2-4min;
Soak heating: the Radix Apioris Fortunei (Radix Lespedezae Buergeri) solution of microwave extracting is heated, and heating and temperature control is at 35-45 ℃, time 15-30min, and heating is beneficial to oozing out of effective ingredient;
Enzymatic saccharification: with the water soluble starch in the a-amylase decomposition Radix Apioris Fortunei (Radix Lespedezae Buergeri) solution, amylase consumption 2-3g/100L, 28-33 ℃ of the temperature of amylase Treatment Solution, enzyme processing time 6-8h, the starch in the enzymolysis solution fully;
Secondary filter: earlier with 100 mesh filter screen elimination medicinal residues, the reuse diatomite filter is crossed the fine particle thing in the elimination solution, helps the drying of spray dryer like this with the Radix Apioris Fortunei (Radix Lespedezae Buergeri) solution behind the amylorrhexis;
Atomization drying: the Radix Apioris Fortunei (Radix Lespedezae Buergeri) solution after the filtration adopts the pressure type atomizing dryer to carry out drying, and the atomization drying temperature is controlled at 45-50 ℃, carries out the solution atomization drying under atomisation pressure 5000KPa;
Pelletize tabletting: take by weighing Radix Apioris Fortunei (Radix Lespedezae Buergeri) xeraphium 40%, maltose 50%, aspartame 0.5%, sweet glycan 0.5%, citric acid 3%, malic acid 1%, vitamin C 1%, Mel 3% by weight proportion, mixed 80 mesh sieves, adding 95% ethanol mixes wet, granulate with 20 mesh sieves, behind 60 ℃ of hot air dryings, after adding magnesium stearate 1% abundant mix homogeneously again, carry out tabletting, quality inspection, packing making finished product 500mg~1000mg/ buccal tablet.
CN201110006136XA 2011-01-13 2011-01-13 Preparation method of hemsley rockvine root lozenge for diminishing inflammation and resisting viruses Expired - Fee Related CN102078366B (en)

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Cited By (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102526143A (en) * 2012-02-07 2012-07-04 杨军 Preparation method of radix glehniae lung clearing and yin nourishing medicinal granules
CN102526362A (en) * 2012-02-01 2012-07-04 杨军 Method for preparing heat-clearing inflammation-eliminating radix tetrastigme oral liquid
CN102578463A (en) * 2012-03-20 2012-07-18 杨军 Methods for preparing raw juice of coix seed, and preparing oral liquid, granules and buccal tablets by using raw juice of coix seed
CN102846698A (en) * 2012-08-20 2013-01-02 浙江中医药大学中药饮片有限公司 Wall-broken radix tetrastigme oral decoction pieces
CN103127315A (en) * 2013-02-25 2013-06-05 胡馨尹 Hemsley rockvine root tuber used for treating lupus erythematosus
CN103169815A (en) * 2013-04-09 2013-06-26 丽水市莲都区绿谷三叶青珍稀植物研究所 Radix tetrastigme lozenge and preparation method thereof
WO2014100410A1 (en) * 2012-12-20 2014-06-26 Cargill, Incorporated Composition comprising steviol glycoside and maltose
CN105504076A (en) * 2015-12-01 2016-04-20 浙江中医药大学 Tetrastigma hemsleyanum Diels et Gilg root tuber polysaccharide with anti-pyretic and anti-inflammatory functions and application of Tetrastigma hemsleyanum Diels et Gilg root tuber polysaccharide
CN105878124A (en) * 2016-06-03 2016-08-24 宁波圣旺生物科技有限公司 Radix tetrastigme toothpaste and preparation method thereof
CN107737201A (en) * 2017-12-01 2018-02-27 山东中医药大学 Lemna paucicostata antivirus action application
CN108671090A (en) * 2018-05-24 2018-10-19 长沙小如信息科技有限公司 A kind of preparation method of radix tetrastigme broken wall oral medicinal slice
CN112618661A (en) * 2021-01-14 2021-04-09 浙江天皇药业有限公司 Antiviral traditional Chinese medicine composition and preparation method and application thereof

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CN1723953A (en) * 2005-07-08 2006-01-25 胡馨尹 Herb medicine
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Cited By (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102526362A (en) * 2012-02-01 2012-07-04 杨军 Method for preparing heat-clearing inflammation-eliminating radix tetrastigme oral liquid
CN102526143A (en) * 2012-02-07 2012-07-04 杨军 Preparation method of radix glehniae lung clearing and yin nourishing medicinal granules
CN102578463A (en) * 2012-03-20 2012-07-18 杨军 Methods for preparing raw juice of coix seed, and preparing oral liquid, granules and buccal tablets by using raw juice of coix seed
CN102846698A (en) * 2012-08-20 2013-01-02 浙江中医药大学中药饮片有限公司 Wall-broken radix tetrastigme oral decoction pieces
WO2014100410A1 (en) * 2012-12-20 2014-06-26 Cargill, Incorporated Composition comprising steviol glycoside and maltose
CN103127315A (en) * 2013-02-25 2013-06-05 胡馨尹 Hemsley rockvine root tuber used for treating lupus erythematosus
CN103169815A (en) * 2013-04-09 2013-06-26 丽水市莲都区绿谷三叶青珍稀植物研究所 Radix tetrastigme lozenge and preparation method thereof
CN105504076A (en) * 2015-12-01 2016-04-20 浙江中医药大学 Tetrastigma hemsleyanum Diels et Gilg root tuber polysaccharide with anti-pyretic and anti-inflammatory functions and application of Tetrastigma hemsleyanum Diels et Gilg root tuber polysaccharide
CN105878124A (en) * 2016-06-03 2016-08-24 宁波圣旺生物科技有限公司 Radix tetrastigme toothpaste and preparation method thereof
CN107737201A (en) * 2017-12-01 2018-02-27 山东中医药大学 Lemna paucicostata antivirus action application
CN108671090A (en) * 2018-05-24 2018-10-19 长沙小如信息科技有限公司 A kind of preparation method of radix tetrastigme broken wall oral medicinal slice
CN112618661A (en) * 2021-01-14 2021-04-09 浙江天皇药业有限公司 Antiviral traditional Chinese medicine composition and preparation method and application thereof

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