CN101954047B - Medicine for treating prolapse of lumbar intervertebral disc - Google Patents

Medicine for treating prolapse of lumbar intervertebral disc Download PDF

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CN101954047B
CN101954047B CN2010102912812A CN201010291281A CN101954047B CN 101954047 B CN101954047 B CN 101954047B CN 2010102912812 A CN2010102912812 A CN 2010102912812A CN 201010291281 A CN201010291281 A CN 201010291281A CN 101954047 B CN101954047 B CN 101954047B
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intervertebral disc
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lumbar intervertebral
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CN101954047A (en
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徐海彬
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Abstract

The invention discloses a medicine for treating prolapse of lumbar intervertebral disc, which is prepared from the following traditional Chinese medicines serving as raw material medicines in part by weight: 10 to 20 parts of angelica, 10 to 20 parts of szechuan lovage rhizome, 10 to 20 parts of white paeony root, 10 to 20 parts of trogopterus dung, 10 to 20 parts of rhizoma corydalis, 10 to 20 parts of common burreed rhizome, 10 to 20 parts of zedoary, 10 to 20 parts of eucommia bark, 20 to 40 parts of astragalus, 8 to 15 parts of earthworm, 20 to 40 parts of common monkshood mother root, 20 to 40 parts of kusnezoff monkshood root, 8 to 15 parts of frank incense and 8 to 15 parts of myrrh. The raw material medicines are mixed and crushed into fine powder so as to prepare powder. The medicine has the effects of dispelling cold and dampness, eliminating pathogenic wind, dredging the meridian and stopping pain, and has the advantages of short treatment course and obvious treatment effect for treating the prolapse of lumbar intervertebral disc. Through treatment effect observation of clinical 60 cases of patients, 34 cases of patients are cured, 17 cases of patients are improved, 9 cases of patients fail, and the total effective rate is 85 percent.

Description

The medicine of treatment prolapse of lumbar intervertebral disc
Technical field
The present invention relates to a kind of medicine for the treatment of prolapse of lumbar intervertebral disc, particularly relating to a kind of is the medicine of the treatment prolapse of lumbar intervertebral disc of crude drug preparation with Chinese medicine.
Background technology
The main clinical manifestation of prolapse of lumbar intervertebral disc is:
1, flank pain
Lumbago is generally first symptom of prolapse of lumbar intervertebral disc, can appear at after the tangible wound such as work, vigorous exercise, bruise, also can not have tangible inducement.The scope of lumbago is more extensive, but main infra waist and lumbosacral region, based on the time heavy dull pain when light, acute stage, can be torn the sample sharp pain, can alleviate during flat crouching, stand or when bending over activity pain increase the weight of.Waist has local tenderness, percussion pain and diffusing property pain, simultaneously visible waist muscle spasm, and lumbar function is limited, and lumbar vertebra physiology is anteflexion to diminish or disappears and be flat waist.Lumbar vertebra lateral bending deformity, both shoulders are not contour, and buttocks is to peculiar posture such as a lateral deviation is askew.
2, a side or bilateral lower limb radiating pain
The lower limb radiating pain occurs before taking place, and also can occur after lumbago takes place or simultaneously.Pain is the radioactivity twinge mainly along buttocks, thigh and posterior leg to heel or the instep, and severe patient can be electric shock sample pain.Cough, sneeze, firmly all can make that the pain increased during bowel movement.This lower limb radiated pain shows as a side, can have also that a side light stresses, the alternative situation in the left and right sides, and minority central type prolapse of lumbar intervertebral disc then is the equal pain of lower limb.
3, lower limb paraesthesia
Outside stolidity behind the Ipsilateral lower limb is sent out cold and is afraid of cold, and particularly toes tip skin temperature drop is low, occurs abnormal sensories such as the sense of ant row, burn feeling sometimes.Behind the lower limb outside stolidity with can follow appearance with the lower limb radiated pain, and be everlasting later time of the paraesthesia of toes occurs.
4, muscular strength weakens or paralyses
When outstanding intervertebral disc pressuring neural root is serious, can produces paralysis neuralis and cause muscle strength and weaken even paralyse.This mostly is waist 4-5 intervertebral disk hernia, due to waist 5 root compressions are benumbed.Tibialis anterior, and brevis and brevis, musculus extensor hallucis longus, extensor digitorum longus paralysis generally can occur, show as and stretch the decline of thumb power, weight person shows as drop foot.
5, deformity of spine or intermittent pond row
The patient who suffers from prolapse of lumbar intervertebral disc, major part exists lumbar vertebra lateral bending deformity, body to lopsidedness in varying degrees, waist can not stretch, buttocks is askew to a lateral deviation, is a kind of distinctive posture, and performance has tangible pond row, can increase the weight of along with the distance of walking, through the stop of short time or squat and have a rest and alleviate, move in circles like this, be intermittent pond row.When the reason of its generation may be with intervertebral disk hernia due to the secondary lumbar spinal stenosis.
6, cauda equina nerve symptom
The prolapse of lumbar intervertebral disc of central type, if outthrust is bigger, or the canalis spinalis bone is narrow, can oppress cauda equina nerve, perineal position numbness, twinge occur, urinates, defecation inability; Urinary incontinence can appear in the women, and sexual impotence can appear in the male.
Prolapse of lumbar intervertebral disc be a kind of clinically see disease more, for seeing, the course of disease is protracted course of disease often more with 30~50 years old person between twenty and fifty, had had a strong impact on patient's live and work.At present the clinical treatment of prolapse of lumbar intervertebral disc has manipulation, hot compress traction, oral medicinal herb method and some substantially as any special measures such as small needle knife, crochet hooks, but clinical practice is all unsatisfactory.
Summary of the invention
The purpose of this invention is to provide that a kind of curative effect is fast, the medicine of the treatment prolapse of lumbar intervertebral disc of short treating period.
Medicine of the present invention is that crude drug prepares by following parts by weight of traditional Chinese medicines:
Radix Angelicae Sinensis 10~20 Rhizoma Chuanxiongs 10~20 Radix Paeoniae Albas 10~20
Oletum Trogopterori 10~20 Rhizoma Corydalis 10~20 rhizoma sparganic 10~20
Rhizoma Curcumae 10~20 Cortexs Eucommiae 10~20 Radixs Astragali 20~40
Pheretima 8~15 Radix Aconitis 20~40 Radix Aconiti Kusnezoffii 20~40
Olibanum 8~15 Myrrhas 8~15.
The preferred weight umber of described each crude drug is:
Radix Angelicae Sinensis 15 Rhizoma Chuanxiongs 15 Radix Paeoniae Albas 15
Oletum Trogopterori 15 Rhizoma Corydalis 15 rhizoma sparganic 15
Rhizoma Curcumae 15 Cortexs Eucommiae 15 Radixs Astragali 30
Pheretima 10 Radix Aconitis 30 Radix Aconiti Kusnezoffii 30
Olibanum 10 Myrrhas 10.
The medicine of above-mentioned each component can be made said peroral dosage form on any pharmaceuticss such as tablet, pill, powder, capsule, and the preferred dosage form of the present invention is a powder.
Above-mentioned each crude drug is removed impurity, clean, mix, be ground into fine powder, make the powder of brown after the sterilization, pack, every bag 10 gram according to described parts by weight.
The crude drug that also contains following parts by weight in the medicine of the present invention:
Radix Achyranthis Bidentatae 10~20 Radix Dipsaci 10~20 Herba Taxillis 10~20
Caulis Spatholobi 10~20 Cortex Acanthopanciss 10~20.
The preferred weight umber of described each crude drug is:
Radix Achyranthis Bidentatae 15 Radix Dipsaci 15 Herba Taxillis 15
Caulis Spatholobi 15 Cortex Acanthopanciss 15.
In the prescription of the present invention, the Radix Angelicae Sinensis promoting blood circulation and stopping pain is moisturized laxation; The Rhizoma Chuanxiong blood circulation promoting and blood stasis dispelling, wind-expelling pain-stopping is suitable for the various diseases of stagnation of blood stasis; The Radix Paeoniae Alba is nourished blood and seeks, relieving spasm to stop pain, and the yin fluid astringing suppressing the hyperactive liver cures mainly side of body rib epigastric pain, limb pain twin; Oletum Trogopterori cures mainly air-cooled QI and blood and closes, brothers' physical distress, cold fiber crops; The Rhizoma Corydalis promoting blood circulation to remove blood stasis, regulating QI to relieve pain is controlled all pains of trusted subordinate's waist knee joint; The circulation of qi promoting of rhizoma sparganic removing blood stasis, removing food stagnancy pain relieving, Yong Yu mass in the abdomen mass in the abdomen, blood stasis amenorrhea, food stagnation distending pain; Rhizoma Curcumae relieves internal heat anticancer, the broken detumescence of becoming silted up, and the slow pain of row, completely pain of strongly fragrant pain due to disorder of QI, the stagnation of QI is used for stagnating; Cortex Eucommiae heat-clearing and toxic substances removing, relieving diarrhea with astringents, cooling blood for hemostasis; Radix Astragali invigorating QI to consolidate the body surface resistance, raise immunity; Pheretima heat clearing away arresting convulsion, collateral dredging is relievingd asthma, and is used for arthralgia, numb limbs and tense tendons; Radix Aconiti expelling wind and removing dampness, antalgic; Radix Aconiti Kusnezoffii promoting flow of QI and blood, removing blood stasis to promote tissue regeneration; The pain relieving of Olibanum regulating qi and activating blood; The Myrrha blood blood stasis removing that looses, subduing swelling and relieving pain; All medicine compatibilities, dispelling cold and dampness, loose ailment said due to cold or exposure, the meridian dredging, the pain that relieves the pain, treatment prolapse of lumbar intervertebral disc short treating period, evident in efficacy.
If Radix Achyranthis Bidentatae promoting blood circulation, removing blood stasis and relieving pain in addition, liver and kidney tonifying; Radix Dipsaci invigorating the liver and kidney, strengthening bone and muscle, strong waist foot, treat all numbness; Herba Taxilli pursues bad odor, removes contraction suddenly; The Caulis Spatholobi tonifying the blood and stretching the tendon, dispelling, collateral-activating; Cortex Acanthopancis damp-clearing pain-relieving, liver and kidney tonifying, fill blood; Then obvious for the prolapse of lumbar intervertebral disc waist shank symptom curative effect of aching.
For further investigating the clinical efficacy of Drug therapy prolapse of lumbar intervertebral disc of the present invention, select 60 routine patients with lumbar disc herniation to carry out clinical observation on the therapeutic effect.
Clinical data:
Select outpatient's 60 examples, wherein male 32 examples, women 28 examples, the course of disease 5 months~11 years, 21~62 years old age.
All case all meets the standard of " disease of tcm diagnosis criterion of therapeutical effect " prolapse of lumbar intervertebral disc: 1, waist wound, chronic strain are arranged or be subjected to the cold-damp history.Most of patient has the chronic back pain history at premorbid.2, lumbago is to buttocks and lower limb radiation, and abdominal pressure increases, and pain increases the weight of when cough, sneeze.3, scoliosis, the lumbar vertebra physiologic radian disappears, and the diseased region vertebra is other the tenderness sense, and to lower limb radiation, waist limitation of activity.4, the lower limb innervation district that gets involved feels irritatedly or blunt, and amyotrophy can appear in course of disease elder.Straight lower limb is raised or is strengthened the test positive, and knee joint, Achilles tendon reflex weaken or disappear, and the big toe back of the body power of stretching weakens.5, the X line is taken the photograph the sheet inspection: scoliosis, and waist physiology lordosis disappears, and the pathological interspinal dish may narrow down, and neighboring edge has osteophytosis.CT examination can show the position and the degree of intervertebral disk hernia.
Therapeutic Method:
Oral medicine of the present invention, morning every day, evening respectively take 1 time, each 10 grams, mixing in water for oral taking.One month is a course of treatment, takes 2 courses of treatment.Period in a medicine fasting raw food, irritable food such as greasy, pungent.
Criterion of therapeutical effect:
Cure: lumbago and skelalgia disappears, and straight lower limb is raised more than 70 degree, can recover former work.
Take a turn for the better: lumbago and skelalgia alleviates, and the waist movable function improves.
Invalid: symptom, sign do not have improvement.
Therapeutic outcome:
2 courses of treatment of 60 routine patient's oral administration Drug therapy of the present invention, cure 34 examples, take a turn for the better 17 examples, invalid 9 examples, total effective rate 85%.
The specific embodiment
Embodiment 1
Take by weighing and remove impurity, the Radix Angelicae Sinensis 1.8kg that cleans up, Rhizoma Chuanxiong 1.6kg, Radix Paeoniae Alba 1.8kg, Oletum Trogopterori 1.2kg, Rhizoma Corydalis 1.2kg, rhizoma sparganic 1.2kg, Rhizoma Curcumae 1.2kg, Cortex Eucommiae 1.8kg, Radix Astragali 2.5kg, Pheretima 1.2kg, Radix Aconiti 2.5kg, Radix Aconiti Kusnezoffii 2.5kg, Olibanum 0.8kg, Myrrha 0.8kg mix homogeneously, be ground into 100 purpose fine powders, pack, restrain for every bag 10, make the powder of brown behind the sterilization.
Embodiment 2
Take by weighing and remove impurity, the Radix Angelicae Sinensis 1.5kg that cleans up, Rhizoma Chuanxiong 1.5kg, Radix Paeoniae Alba 1.5kg, Oletum Trogopterori 1.5kg, Rhizoma Corydalis 1.5kg, rhizoma sparganic 1.5kg, Rhizoma Curcumae 1.5kg, Cortex Eucommiae 1.5kg, Radix Astragali 3kg, Pheretima 1kg, Radix Aconiti 3kg, Radix Aconiti Kusnezoffii 3kg, Olibanum 1kg, Myrrha 1kg mix homogeneously, be ground into 100 purpose fine powders, pack, restrain for every bag 10, make the powder of brown behind the sterilization.
Embodiment 3
Take by weighing and remove impurity, the Radix Angelicae Sinensis 1.2kg that cleans up, Rhizoma Chuanxiong 1.2kg, Radix Paeoniae Alba 1.6kg, Oletum Trogopterori 1.6kg, Rhizoma Corydalis 1.6kg, rhizoma sparganic 1.6kg, Rhizoma Curcumae 1.6kg, Cortex Eucommiae 1.2kg, Radix Astragali 3kg, Pheretima 0.8kg, Radix Aconiti 2.5kg, Radix Aconiti Kusnezoffii 2.5kg, Olibanum 1.2kg, Myrrha 1.2kg mix homogeneously, be ground into 100 purpose fine powders, pack, restrain for every bag 10, make the powder of brown behind the sterilization.
Embodiment 4
Take by weighing and remove impurity, the Radix Angelicae Sinensis 1.5kg that cleans up, Rhizoma Chuanxiong 1.5kg, Radix Paeoniae Alba 1.5kg, Oletum Trogopterori 1.5kg, Rhizoma Corydalis 1.5kg, rhizoma sparganic 1.5kg, Rhizoma Curcumae 1.5kg, Cortex Eucommiae 1.5kg, Radix Astragali 3kg, Pheretima 1kg, Radix Aconiti 3kg, Radix Aconiti Kusnezoffii 3kg, Olibanum 1kg, Myrrha 1kg, Radix Achyranthis Bidentatae 1.5kg, Radix Dipsaci 1.5kg, Herba Taxilli 1.5kg, Caulis Spatholobi 1.5kg, Cortex Acanthopancis 1.5kg mix homogeneously, be ground into 100 purpose fine powders, pack, restrain for every bag 10, make the powder of brown behind the sterilization.
Embodiment 5
Take by weighing and remove impurity, the Radix Angelicae Sinensis 2kg that cleans up, Rhizoma Chuanxiong 2kg, Radix Paeoniae Alba 2kg, Oletum Trogopterori 2kg, Rhizoma Corydalis 2kg, rhizoma sparganic 1kg, Rhizoma Curcumae 1kg, Cortex Eucommiae 2kg, Radix Astragali 2.5kg, Pheretima 1.2kg, Radix Aconiti 3kg, Radix Aconiti Kusnezoffii 3kg, Olibanum 1kg, Myrrha 1kg, Radix Achyranthis Bidentatae 1.2kg, Radix Dipsaci 1.2kg, Herba Taxilli 2kg, Caulis Spatholobi 2kg, Cortex Acanthopancis 2kg mix homogeneously, be ground into 100 purpose fine powders, pack, restrain for every bag 10, make the powder of brown behind the sterilization.

Claims (4)

1. the medicine of treatment prolapse of lumbar intervertebral disc is to be that crude drug prepares by following parts by weight of traditional Chinese medicines:
Figure FSB00000584008900011
2. the medicine of treatment prolapse of lumbar intervertebral disc according to claim 1, wherein the parts by weight of each crude drug are:
Figure FSB00000584008900012
3. the medicine of treatment prolapse of lumbar intervertebral disc is to be that crude drug prepares by following parts by weight of traditional Chinese medicines:
Figure FSB00000584008900013
4. the medicine of treatment prolapse of lumbar intervertebral disc according to claim 3, wherein the parts by weight of each crude drug are:
Figure FSB00000584008900014
CN2010102912812A 2010-09-19 2010-09-19 Medicine for treating prolapse of lumbar intervertebral disc Expired - Fee Related CN101954047B (en)

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CN1250276C (en) * 2003-10-30 2006-04-12 王志臣 Drug for curing disease of proplapse of lumbar intervertebral disc
CN101766775A (en) * 2008-12-31 2010-07-07 何顺洪 Medicine for treating lumbar disc herniation and osteoproliferation

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