CN101953959A - Chinese medicament for treating diabetic gastroparalysis - Google Patents

Abstract

The invention discloses a Chinese medicament for treating diabetic gastroparalysis, which belongs to the field of Chinese medicaments for treating diabetes mellitus and aims to achieve good effect and quick response. The Chinese medicament is prepared from the raw materials of lightyellow sophora roots, glossy ganoderma, pseudo-ginseng, Chinese angelica, official magnolia bark, pinellia tuber, radish seeds and the like. The Chinese medicament has the effects of supporting right, banking the root up, boosting qi, nourishing the blood, quickening the blood, transforming stasis, clearing heat and drying dampness, dispersing glomus and transforming accumulations, and has the advantages of remarkable effects, remarkable potency and relatively quicker response.

Description

A kind of Chinese medicine for the treatment of diabetic gastroparalysis

Technical field

The invention belongs to the field of Chinese medicines of treatment diabetes.

Background technology

The pathological changes of diabetes complicated stomach mainly is diabetic gastroparalysis (gastroparesis), is that a kind of stomach motor function is unusual, and gastric peristalsis weakens or disappears, and makes gastric emptying obstacle occur.Diabetics has 20%～30% concurrent this disease is arranged approximately, is a bigger illness colony.The present Chinese medicine that is intended to treat diabetic gastroparalysis, the deficiency that has two aspects: the one, effect is obvious inadequately, the 2nd, it is slower to take effect, so that large quantities of diabetic gastroparesis persons are glutted after meal for a long time owing to the treatment that can not get active drug, nausea and vomiting, the pain anorexia, dyspepsia has a strong impact on quality of life, and the patient is dissatisfied to this.

At the problem of above-mentioned proposition, the invention provides a kind of Chinese medicine for the treatment of diabetic gastroparalysis, it is obvious inadequately that it can solve in this type of treatment by Chinese herbs in the past effect, the slower problem that takes effect, effective, instant effect, it is remarkable to have effect, drug effect is definite, the advantage of quick result.

Summary of the invention

The present invention is achieved through the following technical solutions:

1, a kind of Chinese medicine for the treatment of diabetic gastroparalysis adopts the raw material of Chinese medicine preparation, and filling a prescription is (by weight):

Radix Sophorae Flavescentis 5---9 parts of 15 portions of Ganodermas 6---18 portions of Radix Notoginseng 3---

Radix Angelicae Sinensis 6---15 parts of 18 parts of Cortex Magnoliae Officinalis 5---15 parts of Rhizoma Pinelliaes 5---

Semen Raphani 5---15 parts

The Chinese medicine of this treatment diabetic gastroparalysis is made by following method:

(1) by above-mentioned weight ratio, Ganoderma is extracted ganoderan with decoction and alcohol sedimentation technique, technological process is as follows: Ganoderma is broken into graininess, cross 40 mesh sieves →, concentrate → mixed, leave standstill 10-12 hour, centrifugal → as to add 75% ethanol with 95% ethanol of 3 times of volumes with 1: 20 hot water (95 ℃) lixiviate → lixiviating solution decompression, precipitate polysaccharide → dry the ganoderan extract fine powder;

(2) by above-mentioned weight ratio, Radix Sophorae Flavescentis, Radix Angelicae Sinensis, Cortex Magnoliae Officinalis, the Rhizoma Pinelliae, Semen Raphani are extracted through conventional water extraction process, make extract extractum fine powder;

(3) by above-mentioned weight ratio, Radix Notoginseng is ground into fine powder, mixes, stir, make Chinese medicine granules, capsule, tablet with above-mentioned (1), (2) two kinds of extract fine powders.

The present invention is according to the folk tradition prescription, and the theory according to traditional Chinese medical science the body resistance strengthening and constitution consolidating, blood circulation promoting and blood stasis dispelling develops meticulously.We think that diabetes complicated gastroparalysis is impaired the causing of neural face owing to the motion of domination stomach in research.Reason is that diabetics immunity is generally low, and is deficient serious, deficiency-fire produced in the interior with the passing of time, and scorching impairment of YIN, blood is sticky, and it is not smooth to flow, and causes the stomach blood supply insufficiency, and neural the mistake supported, gastric hypokinesia, wriggling is reduction significantly.Control when attach most importance to benefiting QI and nourishing blood, blood circulation promoting and blood stasis dispelling, relieving and eliminating mass with " setting upright ".Ganoderma, Radix Angelicae Sinensis, Radix Notoginseng the body resistance strengthening and constitution consolidating among the we, benefiting QI and nourishing blood, blood circulation promoting and blood stasis dispelling, enhancing human body immunity power, " removing " of immunity makes blood clean, viscosity descends, rich mobile, " reparation " effect of immunity then makes impaired its original wriggling of nervus gastrica stomach function regulating organized renewing, digestive function, and this is the key of this disease of treatment; Minister dispels the wind with the Radix Sophorae Flavescentis heat clearing and damp drying, and is antibiotic, diuresis.; Assistant is with the Cortex Magnoliae Officinalis therapeutic method to keep the adverse QI flowing downwards painful abdominal mass that disappears, Rhizoma Pinelliae dissipating phlegm and resolving masses, and it is more outstanding that two medicines share the power of circulation of qi promoting intestinal stasis relieving, stomach function regulating eliminating stagnation; Be aided with the Semen Raphani removing stagnancy of indigested food and making QI downward and reduce phlegm, to separate the disease of distension and fullness in the abdomen.All medicine compatibilities bring out the best in each other, and play the body resistance strengthening and constitution consolidating altogether, benefiting QI and nourishing blood, and blood circulation promoting and blood stasis dispelling, heat clearing and damp drying, the merit of relieving and eliminating mass, effective, instant effect, it is remarkable to have effect, and drug effect is definite, the advantage of quick result.

The specific embodiment

By following embodiment the present invention is done and to specify:

1, get following prescription (weight is unit by gram):

Radix Sophorae Flavescentis 50 kairine sesames 60 gram Radix Notoginseng 30 grams

The Radix Angelicae Sinensis 60 gram Cortex Magnoliae Officinalis 50 gram Rhizoma Pinelliaes 50 grams

Semen Raphani 50 grams

Weight is extracted Ganoderma with decoction and alcohol sedimentation technique in accordance with regulations; With conventional water extraction process Radix Sophorae Flavescentis, Radix Angelicae Sinensis, Cortex Magnoliae Officinalis, the Rhizoma Pinelliae, Semen Raphani are extracted, make extract fine powder 64 grams altogether, Radix Notoginseng is ground into fine powder, mix with said extracted thing fine powder, stir, make fine particle, the capsule of packing into No. 0, make 335 of Chinese medicinal capsules, every capsules includes Chinese medicine fine powder and extract 0.28 gram.

2, get following prescription (weight is unit by gram):

Radix Sophorae Flavescentis 90 kairine sesames 120 gram Radix Notoginseng 60 grams

The Radix Angelicae Sinensis 120 gram Cortex Magnoliae Officinalis 90 gram Rhizoma Pinelliaes 90 grams

Semen Raphani 90 grams

By above-mentioned same method, make 642 of Chinese medicinal capsules, every capsules includes Chinese medicine fine powder and extract 0.28 gram.

3, get following prescription (weight is unit by gram):

Radix Sophorae Flavescentis 140 kairine sesames 180 gram Radix Notoginseng 90 grams

The Radix Angelicae Sinensis 180 gram Cortex Magnoliae Officinalis 140 gram Rhizoma Pinelliaes 140 grams

Semen Raphani 140 grams

By above-mentioned same method, make 978 of Chinese medicinal capsules, every capsules includes Chinese medicine fine powder and extract 0.28 gram.

4, get following prescription (by weight):

3 parts of 7 portions of Radix Notoginseng of 6 portions of Ganodermas of Radix Sophorae Flavescentis

6 parts of 6 parts of Rhizoma Pinelliaes of 7 parts of Cortex Magnoliae Officinalis of Radix Angelicae Sinensis

6 parts of Semen Raphanis

By above-mentioned same method, make Chinese medicinal capsule, every capsules includes Chinese medicine fine powder and extract 0.28 gram.

5, get following prescription (by weight):

7 parts of 16 portions of Radix Notoginseng of 12 portions of Ganodermas of Radix Sophorae Flavescentis

12 parts of 12 parts of Rhizoma Pinelliaes of 16 parts of Cortex Magnoliae Officinalis of Radix Angelicae Sinensis

12 parts of Semen Raphanis

By above-mentioned same method, make Chinese medicinal capsule, every capsules includes Chinese medicine fine powder and extract 0.28 gram.

Clinical data:

The present invention is an example with traditional Chinese medical science diabetic gastroparalysis (gastroparesis), through 8 routine clinical observations.Selecting the tcm diagnosis diabetic gastroparalysis is standard: the diabetics limb adynamia, and stomach pain, upper abdomen is glutted after the meal, dyspepsia, the gastric emptying time is long, and inappetence often has symptoms such as nauseating, vomiting, heartburn, acid regurgitation.As above symptom can be made a definite diagnosis.In making a definite diagnosis the object of observation, male's 4 examples, women's 4 examples do not have other serious disease, and the age is 42 years old-77 years old, 60.3 years old mean age.

Efficacy determination:

1, produce effects: body constitution strengthens, and limbs are strong; Stomach pain, symptoms such as upper abdomen is glutted, dyspepsia, gastric emptying time length are obviously alleviated.

2, effective: body constitution strengthens, stomach pain, and upper abdomen is glutted, and symptoms such as dyspepsia are alleviated to some extent.

3, invalid: the disease no change.

During clinical experiment, except that antidiabetic drug is taken as usual, withdraw other medicines and health nutrient.Take Chinese medicinal capsule of the present invention, observing 3 months is a course of treatment.Instructions of taking: every day 2 times, each 4 capsules, every capsules include Chinese medicine fine powder and extract 0.28 gram, warm water delivery service after meal, symptom promptly has alleviation after 1 month, take 3 months after, symptom is obviously improved.Clinical experiment 8 in, produce effects 4 people, effective 3 people, invalid 1 people, total effective rate 87.5%.

Claims (1)

1. Chinese medicine for the treatment of diabetic gastroparalysis, it is characterized in that: it is to make with the component of following weight ratio: Radix Sophorae Flavescentis 5---15 parts, Ganoderma---18 parts, Radix Notoginseng 3---9 parts, Radix Angelicae Sinensis 6---18 parts, Cortex Magnoliae Officinalis 5---15 parts, the Rhizoma Pinelliae 5---15 parts, Semen Raphani 5---15 parts.