CN101926332A - Bactericide containing hexaconazole and difenoconazole - Google Patents
Bactericide containing hexaconazole and difenoconazole Download PDFInfo
- Publication number
- CN101926332A CN101926332A CN2009102644106A CN200910264410A CN101926332A CN 101926332 A CN101926332 A CN 101926332A CN 2009102644106 A CN2009102644106 A CN 2009102644106A CN 200910264410 A CN200910264410 A CN 200910264410A CN 101926332 A CN101926332 A CN 101926332A
- Authority
- CN
- China
- Prior art keywords
- difenoconazole
- bactericide
- hexaconazole
- azoles alcohol
- composing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
The invention belongs to the technical field of pesticides and relates to a bactericide containing hexaconazole and difenoconazole. The bactericide is used for controlling diseases on grains, fruit trees and vegetables. The active ingredients of the bactericide are hexaconazole and difenoconazole with mass ratio of 1:50-50:1. The bactericide has the following advantages: (1) combining two bactericides, thus expanding the control spectrum of the bactericide; (2) reducing the dosage of the organic solvent and being harmless to the targeted crops, human and livestock and the environment; (3) reducing the application dosage and the application times, being convenient to use, lowering the use cost and having high efficiency, quick effect and long duration; and (4) having simple production method, safe storage and transportation and low environmental impact.
Description
Technical field
The invention belongs to technical field of pesticide, relate to a kind of bactericide that contains own azoles alcohol and Difenoconazole that is used for disease control on cereal, fruit tree and the vegetables.
Background technology
Own azoles alcohol, because name is called (hexaconazole), chemical name is (RS)-2-(2,4 dichloro benzene base)-1-(1H-1,2,4-triazol-1-yl)-hexanol-2; (RS)-and 2-(2,4-dichlorophenyl)-1-(1H-1,2,4-triazole-1-yl) hexan, molecular formula C
14H
17C
I2N
3O
Own azoles alcohol is triazole bactericidal agent.Have wide spectrum, treatment, protect, root out, effect characteristics such as interior suction.The mechanism of action and characteristics sterol demethylation inhibitor destroy and stop the biosynthesis of the cell membrane important composition composition ergosterol of germ, cause cell membrane not form, and make germ death.Have interior suction, protection and therapeutic activity, fungicidal spectrum is wide, can be used for the multiple diseases on crops, fruit tree, the vegetables, as banded sclerotial blight, false smut, powdery mildew, scab, leaf spot etc.
Difenoconazole, English name (difenoconazle), chemical formula is: 1-(2-[4-(4-chlorobenzene oxygen)-2-chlorphenyl]-the 4-methyl isophthalic acid, 3-dioxin-pentane-2-ylmethyl)-H-1,2,4-triazole, molecular formula: C
19H
17C
12N
3O
3Difenoconazole is a kind of systemic fungicide with protection and therapeutic action, is sterol demethylation inhibitor, suppresses the biosynthesis of cell wall sterol, stops fungi growth.It has strong interior absorption, drug effect height, to crop safety, and the characteristics that the lasting period is long.Have prevention and therapeutic action.Fungicidal spectrum is wide, and leaf surface treatment and seed treatment can improve output and the guaranteed quality of crop.Microbial multiple diseases preventive effect for sac fungi and half is splendid.Also can use with, the better prevention effect is all arranged with most of bactericide, Insecticides (tech) ﹠ Herbicides (tech).Multiple diseases on field crop, fruit, the vegetables had treatment and eradicant action.
The single medicament of long-term use makes plant develop immunity to drugs easily and can not reach therapeutic purposes, has not yet to see the relevant record of hexaconazole and difenoconazole composite bactericide product.
Summary of the invention
Technical problem to be solved by this invention is, a kind of good drug efficacy is provided, and effective active control spectrum is wide, can prevent to use that single medicine develops immunity to drugs, the lasting period is long, the bactericide that contains hexaconazole and difenoconazole that cost is low, easy to use.
Bactericide of the present invention, its effective ingredient are hexaconazole and difenoconazole, and the mass ratio of hexaconazole and difenoconazole is 1: 50～50: 1.
The preferable weight ratio of described hexaconazole and difenoconazole is 1: 4～3: 1.
When the bactericide that contains hexaconazole and difenoconazole of the present invention can be for water dispersible granules, medicament is made up of following component and proportion of composing: own azoles alcohol 1%～30%, Difenoconazole 1%～40%, Ricinate 8～20%, binding agent 4～10%, disintegrant 15～25%, the filler surplus, above proportion of composing is a mass percent.
When the bactericide that contains hexaconazole and difenoconazole of the present invention can be for wetting powder, medicament is made up of following component and proportion of composing: own azoles alcohol 1%～30%, Difenoconazole 1%～40%, Ricinate 8～20%, binding agent 4～10%, filler surplus, above proportion of composing are mass percent.
The above wetting dispersing agent can be selected from: one of alkylnaphthalene sulfonate, dodecyl sodium sulfate, lauryl sodium sulfate, sodium lignin sulfonate, trisiloxanes polyethers, APG, sulfonic acid polyformaldehyde condensation product (NNO), calcium lignosulfonate, sodium methylene bis-naphthalene sulfonate, Nekal BX, ethoxylated dodecyl alcohol, aryl phenol APEO, dodecyl polyoxyethylene ether phosphate or sulfuric ester.
The above adhesive can be selected from one of NJ, potassium pyrophosphate, sodium pyrophosphate, malonic anhydride polyethers, gelatin, polyvinyl alcohol, polyvinylpyrrolidone, polyethylene glycol, dextrin.
The above disintegrant can be selected from one of urea, calcium chloride, ammonium sulfate, anhydrous sodium sulfate, salt, sodium carboxymethylcellulose, sodium sulphate, sodium carboxymethyl starch, modification dimethyl siloxane polyethers, alkali earth metal phosphate, soluble starch, polyacrylic acid.
The above filler can be selected from one of kaolin, bentonite, diatomite, potter's clay.
The bactericide that contains hexaconazole and difenoconazole of the present invention can be the aqueous emulsion medicament, and medicament is made up of following component and proportion of composing: own azoles alcohol 5%～10%, Difenoconazole 5%～20%, solvent and cosolvent 2%～20%, emulsifier 3%～10%, antifreezing agent 1%～5%, thickener 0.1%～1%, defoamer 0.1%～0.5%, water surplus; Above proportion of composing is a mass percent.
The bactericide that contains hexaconazole and difenoconazole of the present invention can be the microemulsion medicament, and medicament is made up of following component and proportion of composing: own azoles alcohol 1%～20%, Difenoconazole 1%～30%, solvent and cosolvent 1%～20%, emulsifier 15%～20%, antifreezing agent 1%～5%, defoamer 0.1%～0.5%, water surplus; Above proportion of composing is a mass percent.
Above-described solvent and cosolvent are selected from one or more in methyl alcohol, acetonitrile, ethyl acetate, dimethyl formamide, ethylene glycol, propane diols, toluene, dimethylbenzene, ethanol, cyclohexanone, vegetable oil, N-Methyl pyrrolidone, the N-octylpyrrolidone.
Above-described emulsifier is selected from alkyl benzene calcium sulfonate, the polyoxyethylene nonylphenol ether phosphate, phenyl phenol polyoxy ethyl ether phosphate, styrene polyoxyethylene ether ammonium sulfate salt, alkyl biphenyl ether disulfonic acid magnesium salts, tri ethanol ammonium salt, benzyl dimethyl phenol polyoxy ethyl ether, phenyl phenol polyoxy ethyl ether, alkylphenol formaldehyde resin polyoxyethylene ethyl ether, phenethyl phenol mela mine-formaldehyde resin polyoxy ethyl ether, phenethyl phenol polyoxy ethyl polypropylene-base ether, oxireme-propylene oxide block copolymer, polyoxyethylene nonylphenol ether, castor oil polyoxyethylene ether, alkylaryl polyoxyethylene polyoxypropylene ether, the alkylaryl polyoxyethylene poly-oxygen propylene aether, sorbitan monostearate, the sorbitan fatty acid ester APEO, in the pure APEO of fat one or more.
Above-described antifreeze is selected from one or more in ethylene glycol, glycerine, propane diols, glycerine, polyethylene glycol or the sorbierite.
Above-described thickener is selected from one or more in xanthans, carboxymethyl cellulose, methylcellulose, Magnesiumaluminumsilicate, the polyvinyl alcohol.
Above-described defoamer is selected from one or more in silicone oil, silicone compound, C10-20 saturated fat acid compounds, the C8-10 aliphatic alcohols compound.
Advantage of the present invention is: being used in combination of (1) two kind of bactericide enlarged the bactericidal agent for preventing and treating spectrum; (2) reduced the organic solvent usage amount, to target crop, people and animals, Environmental security; (3) reduce formulation rate, reduce application times, easy to use, reduce use cost, have efficient, quick-acting, the duration is long; (4) production method is simple, storing safety, and environmental influence is little.
Embodiment
The own azoles alcohol of embodiment 1:24% difenoconazole water dispersible granule
The own azoles alcohol of 8g, 16g Difenoconazole, 6g lauryl sodium sulfate, 4g ethoxylated dodecyl alcohol, 3g lignosulfonates, 4g sulfonic acid polyformaldehyde condensation product (NNO), 4g polyethylene glycol, 8g ammonium sulfate, 14g sodium carboxymethylcellulose, kaolin are mended to 100g, make 24% own azoles alcohol difenoconazole water dispersible granule.
The own azoles alcohol of embodiment 2:40% difenoconazole water dispersible granule
The own azoles alcohol of 10g, 30g Difenoconazole, 8g lauryl sodium sulfate, 5g aryl phenol APEO, 2g sodium methylene bis-naphthalene sulfonate, 4g polyethylene glycol, 5g ammonium sulfate, kaolin are mended to 100g, make 40% own azoles alcohol difenoconazole water dispersible granule.
The own azoles alcohol of embodiment 3:12% Difenoconazole wetting powder
The own azoles alcohol of 4g, 8g Difenoconazole, 6g lauryl sodium sulfate, 8g sodium lignin sulfonate, 5g draw back powder (BX), diatomite is supplied 100g.Make 40% own azoles alcohol Difenoconazole wetting powder.
The own azoles alcohol of embodiment 4:20% Difenoconazole wetting powder
The own azoles alcohol of 6g, 14g Difenoconazole, 8g ethoxylated dodecyl alcohol, 10g calcium lignosulfonate, 4g Nekal BX, kaolin are supplied 100g.Make 20% own azoles alcohol Difenoconazole wetting powder.
The own azoles alcohol of embodiment 5:12% Difenoconazole aqueous emulsion
The own azoles alcohol of 4g, 8g Difenoconazole, 5gN-methyl pyrrolidone, 2g alkyl benzene calcium sulfonate, 6g phenethyl phenol mela mine-formaldehyde resin polyoxy ethyl ether, 4g ethylene glycol, 0.4g silicone compound, 0.1g xanthans, 0.8g aluminium-magnesium silicate, water are mended to 100g, make 12% own azoles alcohol Difenoconazole aqueous emulsion.
The own azoles alcohol of embodiment 6:35% Difenoconazole aqueous emulsion
The own azoles alcohol of 10g, 25g Difenoconazole, 7gN, N dimethyl formamide, 8gN-methyl pyrrolidone, 3g phenyl phenol polyoxy ethyl ether phosphate, 4g polyoxyethylene nonylphenol ether, 3g tri ethanol ammonium salt, 4g glycerine, 0.3g silicone compound, 0.5g polyvinyl alcohol, water are mended to 100g, make 35% own azoles alcohol Difenoconazole aqueous emulsion.
Above-mentioned prescription is evenly mixed, active ingredient, solvent, emulsifier are added together, be dissolved into even oil phase; Water, antifreeze, thickener, defoamer are mixed, become the homogeneous water.Under high-speed stirred, water is added oil phase, can make own azoles alcohol Difenoconazole aqueous emulsion.
The own azoles alcohol of embodiment 7:12% micro-emulsion of phenyl ether methyl cyclic-azole
The own azoles alcohol of 3g, 9g Difenoconazole, 7g phenyl phenol polyoxy ethyl ether phosphate, 6g polyoxyethylene nonylphenol ether, 3g vegetable oil, 3gN-methyl pyrrolidone, 5g ethylene glycol, 0.4g silicone compound, water are mended to 100g, emulsifier and water are mixed and made into water, the former medicine that will be dissolved in then in the solvent under agitation adds water, makes 10% own azoles alcohol micro-emulsion of phenyl ether methyl cyclic-azole.
The own azoles alcohol of embodiment 8:20% micro-emulsion of phenyl ether methyl cyclic-azole
The own azoles alcohol of 8g, 12g Difenoconazole, 4g vegetable oil, 6gN-methyl pyrrolidone, 6g polyoxyethylene nonylphenol ether, 5g tri ethanol ammonium salt,, 4g ethylene glycol, 0.2g silicone compound, water mends to 100g, emulsifier and water are mixed and made into water, the former medicine that will be dissolved in then in the solvent under agitation adds water, makes 20% own azoles alcohol micro-emulsion of phenyl ether methyl cyclic-azole.
Oneself the results are shown in Table 1 to strawberry leaves pinta Toxicity Determination by azoles alcohol Difenoconazole implementation of an application example
The own azoles alcohol of table 1 Difenoconazole is to strawberry leaves pinta toxicity test
| Reagent agent | Proportioning | Regression equation (y=a+bx) | EC 50(mg/L) observation | EC 50(mg/L) theoretical value | Synergy ratio (SR) |
| Own azoles alcohol | ? | y＝1.66797+1.7284x? | 1.31? | ? | ? |
| Difenoconazole | ? | y＝3.2572+1.1164x? | 2.36? | ? | ? |
| Own azoles alcohol Difenoconazole | 2∶1? | y＝2.1223+1.6535x? | 1.46? | 1.65? | 1.26? |
| Own azoles alcohol Difenoconazole | 2∶2? | y＝1.9768+1.8244x? | 1.46? | 1.83? | 1.41? |
| Own azoles alcohol Difenoconazole | 2∶3? | y＝2.1317+1.6359x? | 1.23? | 1.94? | 1.58? |
| Own azoles alcohol Difenoconazole | 2∶4? | y＝1.8948+1.5921x? | 1.13? | 1.96? | 1.77? |
| Own azoles alcohol Difenoconazole | 2∶6? | y＝3.0031+1.1247x? | 1.25? | 2.01? | 1.56? |
As shown in Table 1, the composite bactericidal composition of own azoles alcohol of the present invention and Difenoconazole has higher synergistic effect to the strawberry leaves pinta, own azoles alcohol and Difenoconazole proportioning 2: 3,2: 4,2: 6, synergistic effect is obvious, and wherein when own azoles alcohol: synergistic effect is the most outstanding during Difenoconazole=2: 4.
Implementation of an application example two own azoles alcohol Difenoconazole control wheat powdery mildews
The present invention tests and converted water April 22 by every mu of medication amount of formulation and carry out even spraying for 60 kilograms, and dispenser is 3 times altogether, each dispenser 7 days at interval, and after the 3rd dispenser, investigation result such as table 2:
The own azoles alcohol of table 2 Difenoconazole control wheat powdery mildew field control effectiveness test
As seen from Table 2, the present composition is all remarkable to the control efficiency of wheat powdery mildew, than apparently higher than the contrast medicament, wheat is given birth to safety, and bad reaction is not found in the field, and wheat scab, banded sclerotial blight, rust are all had certain preventive effect.
Implementation of an application example three own azoles alcohol Difenoconazoles are prevented and treated rice sheath blight disease
The present invention's test is converted water by every mu of dosage and is carried out even spraying for 60 kilograms, and dispenser is 3 times altogether, each dispenser 10 days at interval, and after the 3rd dispenser, investigation result such as table 3:
The own azoles alcohol of table 3 Difenoconazole is prevented and treated the rice sheath blight disease test of pesticide effectiveness
As seen from Table 3, the present composition has good control efficiency to rice sheath blight disease, and preventive effect all is higher than the contrast medicament, in test dosage scope to crop safety, the advantage that have that quick-acting is good, the lasting period is long, and preventive effect after behind the rice green smut medicine 14 days reached more than 90%.
Implementation of an application example four own azoles alcohol Difenoconazole control pear scabs
The present invention's test is converted water by every mu of medication amount of formulation and is carried out even spraying for 60 kilograms, and dispenser is 3 times altogether, each dispenser 7 days at interval, and after the 3rd dispenser, control efficiency such as table 4:
The own azoles alcohol of table 4 Difenoconazole is prevented and treated the pear scab test of pesticide effectiveness
Find out by table 4, the composite bactericidal composition of own azoles alcohol of the present invention and Difenoconazole has the better prevention effect to pear scab, find in test, said composition is to pear tree safety, and to black rot of pear, rot and black spot, rust, powdery mildew, brown rot, preventive effect all reaches more than 75% after 14 days.
Claims (6)
1. bactericide that contains hexaconazole and difenoconazole, it is characterized in that: its effective ingredient is a hexaconazole and difenoconazole, the mass ratio of hexaconazole and difenoconazole is 1: 50～50: 1.
2. the bactericide that contains hexaconazole and difenoconazole according to claim 1 is characterized in that: the weight ratio of described hexaconazole and difenoconazole is 1: 4～3: 1.
3. the bactericide that contains hexaconazole and difenoconazole according to claim 1, it is characterized in that: this bactericide is a water dispersible granules, medicament is made up of following component and proportion of composing: own azoles alcohol 1%～30%, Difenoconazole 1%～40%, Ricinate 8～20%, binding agent 4～10%, disintegrant 15～25%, filler surplus, above proportion of composing are mass percent.
4. the bactericide that contains hexaconazole and difenoconazole according to claim 1, it is characterized in that: this bactericide is a wetting powder, medicament is made up of following component and proportion of composing: own azoles alcohol 1%～30%, Difenoconazole 1%～40%, Ricinate 8～20%, binding agent 4～10%, the filler surplus, above proportion of composing is a mass percent.
5. the bactericide that contains hexaconazole and difenoconazole according to claim 1, it is characterized in that: this bactericide is the aqueous emulsion medicament, and medicament is made up of following component and proportion of composing: own azoles alcohol 5%～10%, Difenoconazole 5%～20%, solvent and cosolvent 2%～20%, emulsifier 3%～10%, antifreezing agent 1%～5%, thickener 0.1%～1%, defoamer 0.1%～0.5%, water surplus; Above proportion of composing is a mass percent.
6. the bactericide that contains hexaconazole and difenoconazole according to claim 1, it is characterized in that: this bactericide is the microemulsion medicament, and medicament is made up of following component and proportion of composing: own azoles alcohol 1%～20%, Difenoconazole 1%～30%, solvent and cosolvent 1%～20%, emulsifier 15%～20%, antifreezing agent 1%～5%, defoamer 0.1%～0.5%, water surplus; Above proportion of composing is a mass percent.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2009102644106A CN101926332A (en) | 2009-12-22 | 2009-12-22 | Bactericide containing hexaconazole and difenoconazole |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2009102644106A CN101926332A (en) | 2009-12-22 | 2009-12-22 | Bactericide containing hexaconazole and difenoconazole |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN101926332A true CN101926332A (en) | 2010-12-29 |
Family
ID=43365981
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2009102644106A Pending CN101926332A (en) | 2009-12-22 | 2009-12-22 | Bactericide containing hexaconazole and difenoconazole |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN101926332A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103947667A (en) * | 2014-04-18 | 2014-07-30 | 北京明德立达农业科技有限公司 | Disease-resistant composition and application thereof |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101543218A (en) * | 2009-05-06 | 2009-09-30 | 陕西标正作物科学有限公司 | Kresoxim-methyl and triazole bactericide composition and use thereof |
| CN101588718A (en) * | 2006-12-15 | 2009-11-25 | 先正达有限公司 | Formulation |
-
2009
- 2009-12-22 CN CN2009102644106A patent/CN101926332A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101588718A (en) * | 2006-12-15 | 2009-11-25 | 先正达有限公司 | Formulation |
| CN101543218A (en) * | 2009-05-06 | 2009-09-30 | 陕西标正作物科学有限公司 | Kresoxim-methyl and triazole bactericide composition and use thereof |
Non-Patent Citations (1)
| Title |
|---|
| 魏广太 等: "25%苯醚甲环唑EC对水稻纹枯病和稻曲病的防治试验", 《现代农药》 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103947667A (en) * | 2014-04-18 | 2014-07-30 | 北京明德立达农业科技有限公司 | Disease-resistant composition and application thereof |
| CN103947667B (en) * | 2014-04-18 | 2016-02-10 | 北京明德立达农业科技有限公司 | Disease resistance composition and use thereof |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN102204541B (en) | Synergetic antibacterial composition containing trifloxystrobin | |
| CN102017961B (en) | Bactericidal composition containing tridemorph | |
| CN103766350A (en) | Bactericidal composition containing trifloxystrobin and tebuconazole | |
| CN101584323B (en) | Azoxystrobin and hexaconazole-containing antiseptic composition | |
| CN102150678A (en) | Sterilization composition containing prochloraz | |
| CN103798247A (en) | Fungicidal composition containing trifloxystrobin and tebuconazole and application of fungicidal composition | |
| CN103444783B (en) | A kind of bactericidal composition of Fluxapyroxad-containsterilization | |
| CN101617668B (en) | Sterilization composition containing bromothalonil and difenoconazole | |
| CN103283763A (en) | Pesticidal suspended seed coating capable of preventing diseases | |
| CN101755808A (en) | Fungicidal composition containing containing hexaconazole and prochloraz manganese | |
| CN101731231A (en) | Famoxadone-containing and triazole fungicide-containing composition and application thereof | |
| CN103283766A (en) | Pesticidal suspended seed coating capable of preventing diseases | |
| CN102273462A (en) | Novel pesticide composition containing prothioconazole and triazoles | |
| CN101536689B (en) | Bactericidal composition compounded by tetraconazole and difenconazole | |
| CN102204542A (en) | Bactericidal composition containing enostroburin and triazole compound | |
| CN101926332A (en) | Bactericide containing hexaconazole and difenoconazole | |
| CN101999363B (en) | Disinfectant composition containing fenoxanil and triazoles | |
| CN101999380B (en) | Difenoconazole- and propineb-containing pesticidal composition | |
| CN101485312B (en) | Bactericidal composition containing thiabendazole and epoxiconazole and use thereof | |
| CN102077839A (en) | Antibacterial composition containing ipconazole and triazole compounds | |
| CN101543217A (en) | Bactericidal composition containing cyprodinil and tebuconazole | |
| CN101999364A (en) | Hexaconazole-containing germicide composition | |
| CN101731248B (en) | Penconazole-containing and thioneb-containing sterilizing composition | |
| CN101999367B (en) | Flutriafol-containing sterilizing composition | |
| CN103891733A (en) | Composite synergistic bactericidal composition containing bixafen and hexaconazole and application thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20101229 |