CN101889571A - Spinosad soluble agent and preparation method thereof - Google Patents
Spinosad soluble agent and preparation method thereof Download PDFInfo
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- CN101889571A CN101889571A CN2010102201115A CN201010220111A CN101889571A CN 101889571 A CN101889571 A CN 101889571A CN 2010102201115 A CN2010102201115 A CN 2010102201115A CN 201010220111 A CN201010220111 A CN 201010220111A CN 101889571 A CN101889571 A CN 101889571A
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Abstract
The invention discloses a spinosad soluble agent which comprises the following components based on the mass fraction: 2.5%-28% of spinosad bulk drug, 10%-12% of surfactant, 21%-25% of adjuvant and 37%-66% of water. The invention further discloses a preparation method of the spinosad soluble agent, comprising the following steps: proportionally weighing the spinosad bulk drug, the surfactant, the adjuvant and water; placing the materials into a reaction bottle; and under the water bath condition at the temperature of 20-100 DEG C, fully stirring the materials into a transparent liquid to finally obtain the spinosad soluble agent. In the invention, the botanical pesticide spinosad can be dissolved in a solvent to obtain the spinosad soluble agent by adopting a simple, safe and environmental-friendly process, which lays a foundation for application and popularization of the spinosad soluble agent in agricultural production.
Description
Technical field
The present invention relates to a kind of chemical pesticide, especially a kind of soluble concentrate that contains the botanical pesticide multiple killing teichomycin; The invention still further relates to the preparation method of this spinosad soluble agent.
Background technology
At present, the development environment friendly agricultural, particularly biopesticide more and more is subject to people's attention.Wherein the botanical pesticide multiple killing teichomycin is wide, environmentally friendly particularly noticeable because of its active height, insecticidal spectrum.But, because multiple killing teichomycin is water insoluble, solvability is also very low in organic solvent simultaneously, so the multiple killing teichomycin agricultural chemicals mainly adopts suspending agent, missible oil, kills formulations such as ant bait formulation, aqueous emulsion at present, because of being prepared into solution, so promote the use of comparatively difficulty, also fail to accept extensively for people.Thereby the soluble concentrate of research preparation multiple killing teichomycin becomes the current key subjects that need to be resolved hurrily.
Summary of the invention
The technical problem to be solved in the present invention provides a kind of spinosad soluble agent, realizes the dissolving of botanical pesticide multiple killing teichomycin in solvent, so that its application and popularization in agricultural production; For this reason, the present invention also will provide the preparation method of this spinosad soluble agent simultaneously.
For solving the problems of the technologies described above, the technical solution used in the present invention is:
A kind of spinosad soluble agent, it comprises the former medicine of multiple killing teichomycin, surfactant, auxiliary agent and water, and wherein the mass fraction of each component is respectively the former medicine 2.5%～28% of multiple killing teichomycin, surfactant 10%～12%, auxiliary agent 21%～25%, water 37%～66%; Described surfactant is one or more in emulsifier 0201B, emulsifier 0203B, farming breast 1656, farming breast 1657, tween, the sapn, and described auxiliary agent is one or more in methyl alcohol, ethanol, isopropyl alcohol, urea, cyclohexanone, nitrogen dimethylformamide, azone, the ethylene glycol.
A kind of optimal technical scheme of spinosad soluble agent of the present invention is to comprise the former medicine of multiple killing teichomycin, emulsifier 0201B, methyl alcohol, ethylene glycol and water, and wherein the mass fraction of each component is respectively the former medicine 2.95% of multiple killing teichomycin, emulsifier 0201B 10.5%, methyl alcohol 15.8%, ethylene glycol 5.26%, water 65.5%.
The another kind of optimal technical scheme of spinosad soluble agent of the present invention is to comprise the former medicine of multiple killing teichomycin, emulsifier 0201B, ethanol, ethylene glycol and water, and wherein the mass fraction of each component is respectively the former medicine 6.22% of multiple killing teichomycin, emulsifier 0201B 11.1%, ethanol 16.7%, ethylene glycol 5.56%, water 60.4%.
The another kind of optimal technical scheme of spinosad soluble agent of the present invention is to comprise the former medicine of multiple killing teichomycin, emulsifier 0203B, isopropyl alcohol, ethylene glycol, urea and water, and wherein the mass fraction of each component is respectively the former medicine 27.8% of multiple killing teichomycin, emulsifier 0203B 10%, isopropyl alcohol 15%, ethylene glycol 5%, urea 5%, water 37.2%.
The another kind of optimal technical scheme of spinosad soluble agent of the present invention is to comprise the former medicine of multiple killing teichomycin, farming breast 1656, cyclohexanone, nitrogen dimethylformamide, ethylene glycol and water, and wherein the mass fraction of each component is respectively the former medicine 27.8% of multiple killing teichomycin, farming breast 165610%, cyclohexanone 15%, nitrogen dimethylformamide 5%, ethylene glycol 5%, water 37.2%.
The another kind of optimal technical scheme of spinosad soluble agent of the present invention is to comprise the former medicine of multiple killing teichomycin, farming breast 1657, cyclohexanone, nitrogen dimethylformamide, ethylene glycol and water, and wherein the mass fraction of each component is respectively the former medicine 27.8% of multiple killing teichomycin, farming breast 165710%, cyclohexanone 15%, nitrogen dimethylformamide 5%, ethylene glycol 5%, water 37.2%.
The another kind of optimal technical scheme of spinosad soluble agent of the present invention is to comprise the former medicine of multiple killing teichomycin, emulsifier tween, cyclohexanone, azone, ethylene glycol and water, and wherein the mass fraction of each component is respectively the former medicine 27.8% of multiple killing teichomycin, emulsifier tween 10%, cyclohexanone 15%, azone 5%, ethylene glycol 5%, water 37.2%.
The another kind of optimal technical scheme of spinosad soluble agent of the present invention is to comprise the former medicine of multiple killing teichomycin, emulsifier span, cyclohexanone, azone, ethylene glycol and water, and wherein the mass fraction of each component is respectively the former medicine 27.8% of multiple killing teichomycin, emulsifier span 10%, cyclohexanone 15%, azone 5%, ethylene glycol 5%, water 37.2%.
A kind of method for preparing this spinosad soluble agent, its step is: take by weighing the former medicine of multiple killing teichomycin, surfactant, auxiliary agent and water in proportion, place reaction bulb, under 20 ℃～100 ℃ water bath condition, fully stir, promptly get spinosad soluble agent until obtaining transparency liquid; Wherein the mass fraction of each component is respectively the former medicine 2.5%～28% of multiple killing teichomycin, surfactant 10%～12%, auxiliary agent 21%～25%, water 37%～66%; Described surfactant is one or more in emulsifier 0201B, emulsifier 0203B, farming breast 1656, farming breast 1657, tween, the sapn, and described auxiliary agent is one or more in methyl alcohol, ethanol, isopropyl alcohol, urea, cyclohexanone, nitrogen dimethylformamide, azone, the ethylene glycol.
Adopt the beneficial effect that technique scheme produced to be: the multiple killing teichomycin suspending agent of producing with The Dow Agrosciences, LLC. is contrast; get spinosad soluble agent of the present invention and do indoor virulence test; select the diamond-back moth third-instar larvae of uniformity; insert in the culture dish of 9 centimetres of diameters that are placed with cabbage leaf; 30 in every ware; every processing repeats for three times; adopt the spray tower press atomization; every ware spray 3ml; 6 concentration gradients are established in every processing; spray back 48h investigates dead borer population, calculates median lethal concentration LC with method of least squares
50, it is as follows to record the result, spinosad soluble agent LC
50Be 1.81ppm, multiple killing teichomycin suspending agent LC
50Be 1.95ppm, thus the result as seen, the former LC
50LC a little less than the latter
50, illustrating that spinosad soluble agent prescription of the present invention is reasonable, drug effect is remarkable; The present invention has overcome the problem of multiple killing teichomycin indissoluble in water and organic solvent, realized its dissolving in specific solvent, the soluble concentrate that has prepared multiple killing teichomycin, expanded the scope of application of multiple killing teichomycin greatly, simplified its using method, for its large-scale application in agricultural production has been paved road; Solvent used in the present invention is cheap and easy to get, makes that the cost of spinosad soluble agent is very cheap; The preparation technology of spinosad soluble agent of the present invention is very simple, and the working condition gentleness need not any special installation, and does not discharge any pollutant, and environmental protection can be produced large-tonnage product at short notice.
Embodiment
The former medicine of the used multiple killing teichomycin of the present invention is a pale powder shape solid, and effective content is about 90%, and buying is from The Dow Agrosciences, LLC.; All the other components are conventional commercially available prod.
The explanation that following examples are detailed the present invention.
Embodiment 1
A kind of spinosad soluble agent, comprise the former medicine of multiple killing teichomycin, emulsifier 0201B, methyl alcohol, ethylene glycol and water, wherein the mass fraction of each component is respectively the former medicine 2.95% of multiple killing teichomycin, emulsifier 0201B 10.5%, methyl alcohol 15.8%, ethylene glycol 5.26%, water 65.5%.
The method for preparing this spinosad soluble agent is: take by weighing the former medicine of multiple killing teichomycin, surfactant, auxiliary agent and water in proportion, place enamel still, under 20 ℃～100 ℃ water bath condition, fully stir until obtaining transparency liquid, promptly get spinosad soluble agent.In addition, in order to promote the dissolving of multiple killing teichomycin, can also adopt ultrasonic short molten among the preparation technology.
Embodiment 2
A kind of spinosad soluble agent, comprise the former medicine of multiple killing teichomycin, emulsifier 0201B, ethanol, ethylene glycol and water, wherein the mass fraction of each component is respectively the former medicine 6.22% of multiple killing teichomycin, emulsifier 0201B 11.1%, ethanol 16.7%, ethylene glycol 5.56%, water 60.4%.
The preparation method of this spinosad soluble agent is identical with embodiment 1.
Embodiment 3
A kind of spinosad soluble agent, comprise the former medicine of multiple killing teichomycin, emulsifier 0203B, isopropyl alcohol, ethylene glycol, urea and water, wherein the mass fraction of each component is respectively the former medicine 27.8% of multiple killing teichomycin, emulsifier 0203B 10%, isopropyl alcohol 15%, ethylene glycol 5%, urea 5%, water 37.2%.
The preparation method of this spinosad soluble agent is identical with embodiment 1.
Embodiment 4
A kind of spinosad soluble agent, comprise the former medicine of multiple killing teichomycin, farming breast 1656, cyclohexanone, nitrogen dimethylformamide, ethylene glycol and water, wherein the mass fraction of each component is respectively the former medicine 27.8% of multiple killing teichomycin, farming breast 165610%, cyclohexanone 15%, nitrogen dimethylformamide 5%, ethylene glycol 5%, water 37.2%.
The preparation method of this spinosad soluble agent is identical with embodiment 1.
Embodiment 5
A kind of spinosad soluble agent, comprise the former medicine of multiple killing teichomycin, farming breast 1657, cyclohexanone, nitrogen dimethylformamide, ethylene glycol and water, wherein the mass fraction of each component is respectively the former medicine 27.8% of multiple killing teichomycin, farming breast 165710%, cyclohexanone 15%, nitrogen dimethylformamide 5%, ethylene glycol 5%, water 37.2%.
The preparation method of this spinosad soluble agent is identical with embodiment 1.
Embodiment 6
A kind of spinosad soluble agent, comprise the former medicine of multiple killing teichomycin, emulsifier tween, cyclohexanone, azone, ethylene glycol and water, wherein the mass fraction of each component is respectively the former medicine 27.8% of multiple killing teichomycin, emulsifier tween 10%, cyclohexanone 15%, azone 5%, ethylene glycol 5%, water 37.2%.
The preparation method of this spinosad soluble agent is identical with embodiment 1.
Embodiment 7
A kind of spinosad soluble agent, comprise the former medicine of multiple killing teichomycin, emulsifier span, cyclohexanone, azone, ethylene glycol and water, wherein the mass fraction of each component is respectively the former medicine 27.8% of multiple killing teichomycin, emulsifier span 10%, cyclohexanone 15%, azone 5%, ethylene glycol 5%, water 37.2%.
The preparation method of this spinosad soluble agent is identical with embodiment 1.
Foregoing description only proposes as the enforceable technical scheme of the present invention, not as the single restrictive condition to its technical scheme itself.
Claims (9)
1. spinosad soluble agent, it is characterized in that comprising the former medicine of multiple killing teichomycin, surfactant, auxiliary agent and water, wherein the mass fraction of each component is respectively the former medicine 2.5%～28% of multiple killing teichomycin, surfactant 10%～12%, auxiliary agent 21%～25%, water 37%～66%; Described surfactant is one or more in emulsifier 0201B, emulsifier 0203B, farming breast 1656, farming breast 1657, tween, the sapn, and described auxiliary agent is one or more in methyl alcohol, ethanol, isopropyl alcohol, urea, cyclohexanone, nitrogen dimethylformamide, azone, the ethylene glycol.
2. spinosad soluble agent according to claim 1, it is characterized in that comprising the former medicine of multiple killing teichomycin, emulsifier 0201B, methyl alcohol, ethylene glycol and water, wherein the mass fraction of each component is respectively the former medicine 2.95% of multiple killing teichomycin, emulsifier 0201B 10.5%, methyl alcohol 15.8%, ethylene glycol 5.26%, water 65.5%.
3. spinosad soluble agent according to claim 1, it is characterized in that comprising the former medicine of multiple killing teichomycin, emulsifier 0201B, ethanol, ethylene glycol and water, wherein the mass fraction of each component is respectively the former medicine 6.22% of multiple killing teichomycin, emulsifier 0201B 11.1%, ethanol 16.7%, ethylene glycol 5.56%, water 60.4%.
4. spinosad soluble agent according to claim 1, it is characterized in that comprising the former medicine of multiple killing teichomycin, emulsifier 0203B, isopropyl alcohol, ethylene glycol, urea and water, wherein the mass fraction of each component is respectively the former medicine 27.8% of multiple killing teichomycin, emulsifier 0203B 10%, isopropyl alcohol 15%, ethylene glycol 5%, urea 5%, water 37.2%.
5. spinosad soluble agent according to claim 1, it is characterized in that comprising the former medicine of multiple killing teichomycin, farming breast 1656, cyclohexanone, nitrogen dimethylformamide, ethylene glycol and water, wherein the mass fraction of each component is respectively the former medicine 27.8% of multiple killing teichomycin, farming breast 165610%, cyclohexanone 15%, nitrogen dimethylformamide 5%, ethylene glycol 5%, water 37.2%.
6. spinosad soluble agent according to claim 1, it is characterized in that comprising the former medicine of multiple killing teichomycin, farming breast 1657, cyclohexanone, nitrogen dimethylformamide, ethylene glycol and water, wherein the mass fraction of each component is respectively the former medicine 27.8% of multiple killing teichomycin, farming breast 165710%, cyclohexanone 15%, nitrogen dimethylformamide 5%, ethylene glycol 5%, water 37.2%.
7. spinosad soluble agent according to claim 1, it is characterized in that comprising the former medicine of multiple killing teichomycin, emulsifier tween, cyclohexanone, azone, ethylene glycol and water, wherein the mass fraction of each component is respectively the former medicine 27.8% of multiple killing teichomycin, emulsifier tween 10%, cyclohexanone 15%, azone 5%, ethylene glycol 5%, water 37.2%.
8. spinosad soluble agent according to claim 1, it is characterized in that comprising the former medicine of multiple killing teichomycin, emulsifier span, cyclohexanone, azone, ethylene glycol and water, wherein the mass fraction of each component is respectively the former medicine 27.8% of multiple killing teichomycin, emulsifier span 10%, cyclohexanone 15%, azone 5%, ethylene glycol 5%, water 37.2%.
9. method for preparing the described spinosad soluble agent of claim 1, its characterization step is: take by weighing the former medicine of multiple killing teichomycin, surfactant, auxiliary agent and water in proportion, place reaction bulb, under 20 ℃～100 ℃ water bath condition, fully stir, promptly get spinosad soluble agent until obtaining transparency liquid; Wherein the mass fraction of each component is respectively the former medicine 2.5%～28% of multiple killing teichomycin, surfactant 10%～12%, auxiliary agent 21%～25%, water 37%～66%; Described surfactant is one or more in emulsifier 0201B, emulsifier 0203B, farming breast 1656, farming breast 1657, tween, the sapn, and described auxiliary agent is one or more in methyl alcohol, ethanol, isopropyl alcohol, urea, cyclohexanone, nitrogen dimethylformamide, azone, the ethylene glycol.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
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| CN 201010220111 CN101889571B (en) | 2010-07-08 | 2010-07-08 | Spinosad soluble agent and preparation method thereof |
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| Application Number | Priority Date | Filing Date | Title |
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| CN 201010220111 CN101889571B (en) | 2010-07-08 | 2010-07-08 | Spinosad soluble agent and preparation method thereof |
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| CN101889571A true CN101889571A (en) | 2010-11-24 |
| CN101889571B CN101889571B (en) | 2013-02-13 |
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| CN 201010220111 Expired - Fee Related CN101889571B (en) | 2010-07-08 | 2010-07-08 | Spinosad soluble agent and preparation method thereof |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101984814A (en) * | 2010-12-17 | 2011-03-16 | 沈阳市和田化工有限公司 | Pleocidin water formulation pesticide |
| CN102835397A (en) * | 2012-07-04 | 2012-12-26 | 河北威远生物化工股份有限公司 | Spinosad synergistic aqueous emulsion and preparation method thereof |
| CN111758731A (en) * | 2020-06-04 | 2020-10-13 | 广东新景象生物工程有限公司 | Nitenpyram soluble liquid and preparation method thereof |
| CN113016788A (en) * | 2021-03-24 | 2021-06-25 | 赤峰绿水青山生物科技有限公司 | Spinosad soluble agent and preparation method thereof |
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| US20010051175A1 (en) * | 1999-04-12 | 2001-12-13 | Strom Robert M. | Aqueous dispersions of agricultural chemicals |
| CN1989807A (en) * | 2005-12-26 | 2007-07-04 | 北京华京五方实用纳米科技开发有限公司 | Spinosad aqueous emulsion |
| WO2009086741A1 (en) * | 2008-01-09 | 2009-07-16 | Guishu Luan | Water soluble granule of spinosad and its preparation |
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2010
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| US20010051175A1 (en) * | 1999-04-12 | 2001-12-13 | Strom Robert M. | Aqueous dispersions of agricultural chemicals |
| CN1989807A (en) * | 2005-12-26 | 2007-07-04 | 北京华京五方实用纳米科技开发有限公司 | Spinosad aqueous emulsion |
| WO2009086741A1 (en) * | 2008-01-09 | 2009-07-16 | Guishu Luan | Water soluble granule of spinosad and its preparation |
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Non-Patent Citations (1)
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Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101984814A (en) * | 2010-12-17 | 2011-03-16 | 沈阳市和田化工有限公司 | Pleocidin water formulation pesticide |
| CN101984814B (en) * | 2010-12-17 | 2013-06-19 | 沈阳市和田化工有限公司 | Pleocidin water formulation pesticide |
| CN102835397A (en) * | 2012-07-04 | 2012-12-26 | 河北威远生物化工股份有限公司 | Spinosad synergistic aqueous emulsion and preparation method thereof |
| CN111758731A (en) * | 2020-06-04 | 2020-10-13 | 广东新景象生物工程有限公司 | Nitenpyram soluble liquid and preparation method thereof |
| CN111758731B (en) * | 2020-06-04 | 2021-05-07 | 广东新景象生物工程有限公司 | Nitenpyram soluble liquid and preparation method thereof |
| CN113016788A (en) * | 2021-03-24 | 2021-06-25 | 赤峰绿水青山生物科技有限公司 | Spinosad soluble agent and preparation method thereof |
| CN113016788B (en) * | 2021-03-24 | 2022-07-05 | 赤峰绿水青山生物科技有限公司 | Spinosad soluble agent and preparation method thereof |
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| CN101889571B (en) | 2013-02-13 |
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