CN101874888A - Chinese medicinal composition for treating hiccup and preparation method thereof - Google Patents

Chinese medicinal composition for treating hiccup and preparation method thereof Download PDF

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Publication number
CN101874888A
CN101874888A CN2010101542235A CN201010154223A CN101874888A CN 101874888 A CN101874888 A CN 101874888A CN 2010101542235 A CN2010101542235 A CN 2010101542235A CN 201010154223 A CN201010154223 A CN 201010154223A CN 101874888 A CN101874888 A CN 101874888A
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parts
rhizoma
fructus
radix
chinese medicine
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CN101874888B (en
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王峰
王文奎
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Taiyi Hepu Beijing Research Institute of Traditional Chinese Medicine Co Ltd
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Taiyi Hepu Beijing Research Institute of Traditional Chinese Medicine Co Ltd
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Abstract

The invention discloses a new Chinese medicinal composition for treating hiccup and a preparation method thereof. The Chinese medicinal composition mainly comprises the following raw material medicaments: rhubarb, dried orange peel, costus root, cyperus rotundus, rosewood heart wood, Chinese eaglewood, styrax, benzoin, radish seed, Chinese dwarf cherry seed, hemp fruit, persimmon calyx and receptacle, shizandra berry, Chinese angelica, mongolian snakegourd root, grassleaf sweelflag rhizome, tall gastrodia tuber, curcuma longa, ground beeltle, honey-fried frankincense, honey-fried myrrh, immature bitter orange, szechwan chinaberry fruit, longstamen onion bulb, finger citron, rose, jiuxiang bug and the like. The Chinese medicinal composition of the invention can be prepared into any common oral administration preparation according to the conventional method of Chinese medicinal preparations. The Chinese medicinal composition can improve symptoms such as hiccough, hiccup, spasmolygmus, obstruction of flow of qi, stomach qi upward reversal, intermittent feeding infarction, vomit, dysphagia, eating disorder and the like obviously, and has definite clinical effect, obvious curative effect and quick response. The Chinese medicinal composition has the advantages of low cost, no toxic or side effect and the like.

Description

A kind of Chinese medicine composition for the treatment of the cancer of the esophagus and preparation method thereof
Technical field
The present invention relates to a kind of Chinese medicine composition for the treatment of the cancer of the esophagus.Relating in particular to a kind of is the Chinese medicine composition and preparation method thereof of the treatment cancer of the esophagus of crude drug with the Chinese herbal medicine.
Background technology
Dysphagicly be meant that swallowing food chokes with sobs and have some setbacks, inappetence, or receive and the illness of appearing again.How to cause mechanism of qi retardance, adverse rising of stomach-QI because of waiting for a long time in eating and drinking without temperance, feelings will internal injury or prolonged illness year, be the sick class disease of internal organs numbness of main performance with intermittence feed infraction, vomiting.Mostly be painless property acataposis in early days, outstanding especially during with feed thing and cold water, be intermittence more and show effect repeatedly, the course of disease is longer, as seen becomes thin lusterless complexion, diseases such as spiritlessness and weakness after the prolonged illness.Have a strong impact on Health and Living, the clinical onset rate has the trend of continuous rising in recent years.
Modern medicine is at clinical a certain symptom treatment, often fall flat, can not find suitable Therapeutic Method, in order to overcome above-mentioned defective, the present invention is based on the differential diagnosis of diseases and the dialectical principle that combines of the Chinese traditional treatment cancer of the esophagus, treating both the principal and secondary aspects of a disease, deficiency and excess is also controlled, inside and outside logical accent, emergency is taken in concurrently, filter out profit and support the natural plant of Tianjin blood, pathogenic fire reducing eliminating stagnation, dissipating phlegm and keeping the adverse QI downwards, warming and recuperating the spleen and kidney,, be prepared from according to certain weight proportion according to the theory of Chinese medical science prescription.A kind of Chinese medicine composition of evident in efficacy, with low cost, the treatment cancer of the esophagus that toxic and side effects is minimum is provided.
Above-mentioned Chinese medicine composition of the present invention adds various conventional adjuvant required when preparing different dosage forms, for example disintegrating agent, lubricant, adhesive etc. are prepared into any oral formulations commonly used with the method for Chinese medicinal of routine, for example can be: pill, capsule, tablet, powder, granule or oral liquid etc.
Summary of the invention
Technical problem to be solved by this invention is assorted to overcome above-described shortcoming, and a kind of Chinese medicine composition of the treatment cancer of the esophagus of evident in efficacy, with low cost, almost non-toxic side effect is provided.
The technical problem of the desired solution of the present invention realizes by following technological approaches.
A kind of Chinese medicine composition for the treatment of the cancer of the esophagus of the present invention, the component of main following weight portion is formed:
1~50 part of Radix Et Rhizoma Rhei, 1~100 part of Pericarpium Citri Reticulatae, 1~100 part of Radix Aucklandiae (Radix Vladimiriae), 1~120 part of Rhizoma Cyperi, 1~100 part of Lignum Dalbergiae Odoriferae, 1~50 part of Lignum Aquilariae Resinatum, 1~100 part of Herba Lysimachiae foenum-graeci, 1~100 part of Styrax, 1~100 part of Benzoinum, 1~30 part of 1~50 part of Calyx Kaki of Fructus Cannabis, 1~100 part of Radix Angelicae Sinensis, 1~100 part of the Radix Paeoniae Alba, 1~100 part of Radix Trichosanthis, 1~150 part of Rhizoma Acori Graminei, 1~30 part of Borneolum Syntheticum, 1~30 part of Camphora, 1~20 part of Venenum Bufonis, 1~50 part in Rhizoma Gastrodiae, 1~50 part of Eupolyphaga Seu Steleophaga, 1~50 part of Magnetitum, 1~50 part of succinum, 1~50 part in Cinnabaris, process 1~50 part of Squama Manis, 1~50 part of Rhizoma Chuanxiong, 1~50 part of Ramulus Cinnamomi, 1~100 part of Rhizoma Corydalis, 1~100 part in Rhizoma Curcumae Longae, 1~50 part of Olibanum (processed), 1~50 part of Myrrha (processed), 1~120 part of Fructus Aurantii Immaturus, 1~100 part of Fructus Toosendan, 1~100 part of Fructus Citri Sarcodactylis, 1~50 part of Aspongopus, 1~100 part of Massa Medicata Fermentata.
Be preferably:
15 parts of Radix Et Rhizoma Rhei, 50 parts of Pericarpium Citri Reticulataes, 20 parts of Radix Aucklandiae (Radix Vladimiriae), 30 parts of Rhizoma Cyperi, 20 parts of Lignum Dalbergiae Odoriferaes, 10 parts of Lignum Aquilariae Resinatum, 20 parts of Herba Lysimachiae foenum-graeci, 20 parts of Styrax, 20 parts of Benzoinumes, 20 parts of 15 parts of Calyx Kaki of Fructus Cannabis, 20 parts of Radix Angelicae Sinensis, 20 parts of the Radix Paeoniae Albas, 30 parts of Radix Trichosanthis, 50 parts of Rhizoma Acori Graminei, 10 parts of Borneolum Syntheticums, 10 parts of Camphoras, 5 parts of Venenum Bufoniss, 15 parts in Rhizoma Gastrodiae, 15 parts of Eupolyphaga Seu Steleophagas, 15 parts of Magnetitums, 10 parts of succinums, 15 parts in Cinnabaris, process 15 parts of Squama Manis, 15 parts of Rhizoma Chuanxiongs, 15 parts of Ramulus Cinnamomi, 20 parts of Rhizoma Corydalis, 20 parts in Rhizoma Curcumae Longae, 10 parts of Olibanum (processed), 10 parts of Myrrha (processed)s, 50 parts of Fructus Aurantii Immaturuss, 30 parts of Fructus Toosendans, 20 parts of Fructus Citri Sarcodactylis, 15 parts of Aspongopuss, 15 parts of Massa Medicata Fermentata.
The weight portion consumption of each component of Chinese medicine composition of the present invention can also be:
1~50 part of Semen Raphani, 1~50 part of Semen Pruni, 1~50 part of Fructus Schisandrae Chinensis, 1~50 part of Fructus Mume, 1~50 part of Fructus Crataegi, 1~50 part in Fructus Hordei Germinatus, 1~50 part of Endothelium Corneum Gigeriae Galli, 1~50 part of Fructus Amomi, 1~50 part of Cortex Magnoliae Officinalis, 1~50 part of Rhizoma Atractylodis, 1~50 part of Bulbus Allii Macrostemonis, 1~50 part of Aloe, 1~50 part of rhizoma sparganic, 1~50 part of Rhizoma Curcumae, 1~50 part of Radix Salviae Miltiorrhizae, 1~50 part on Flos Carthami, 1~50 part in Semen Persicae, 1~50 part of Flos Rosae Rugosae, 1~50 part of Bombyx Batryticatus, 1~50 part of Caulis Spatholobi.
Be preferably:
15 parts of Semen Raphanis, 10 parts of Semen Prunis, 10 parts of Fructus Schisandrae Chinensis, 10 parts of Fructus Mumes, 10 parts of Fructus Crataegis, 15 parts in Fructus Hordei Germinatus, 15 parts of Endothelium Corneum Gigeriae Galli, 15 parts of Fructus Amomis, 10 parts of Cortex Magnoliae Officinalis, 10 parts of Rhizoma Atractylodis, 15 parts of Bulbus Allii Macrostemonis, 15 parts of Aloes, 15 parts of rhizoma sparganic, 15 parts of Rhizoma Curcumae, 15 parts of Radix Salviae Miltiorrhizaes, 10 parts on Flos Carthami, 10 parts in Semen Persicae, 10 parts of Flos Rosae Rugosaes, 15 parts of Bombyx Batryticatus, 15 parts of Caulis Spatholobis.
Above-mentioned Chinese medicine composition of the present invention adds various conventional adjuvant required when preparing different dosage form, for example disintegrating agent, lubricant, adhesive etc. are prepared into any oral formulations commonly used with the method for Chinese medicinal of routine, for example can be pill, capsule, tablet, powder, granule or oral liquid etc.
Chinese medicine composition of the present invention is opened one's minds based on traditional Chinese medical science the five internal organs differentiation of syndromes of YIN and YANG guiding principle, in conjunction with safe one and Pu innovation theory system " ten thousand diseases ascent theory ", " the five internal organs differentiation of syndromes of YIN and YANG guiding principle ", " three-dimensional conservation regulation and control rule " and clinical treatment " pairing principle " are as instructing, take place in conjunction with disease, development and the rule that changes, classify according to the original new drug system, formation is monarch with " the five internal organs basic function is adjusted; equilibrium between yin and yang coordination side ", " the main pathogenesis of the five internal organs adjustment side " is minister, " therapy of serious disease side " is assistant, " clinical fundamental symptoms symptomatic treatment side " Chinese medicine patent medicine " original new drug system " for making.
The used herbal raw material medicine of the present invention all can be buied from the Chinese medicine shop, and its specification meets national medical standard.
Usage and dosage: dosage of the present invention depends on concrete dosage form, factors such as patient age, body weight, health status.As guidance: for oral administration: 1) capsule: obey 2~5 every day three times at every turn, every content of dispersion 0.4 gram, warm water takes.2) tablet: every day three times, each 2~4, every content of dispersion 0.5 gram, warm water takes.3) pill: every day three times, each 5 grams, warm water takes.4) granule: every day three times.Each 5 grams, warm water takes.5) powder: every day three times, each 3~5 grams, warm water takes.
The treatment that the present invention is directed to cancer of the esophagus patient is very effective, various crude drug are coordinated mutually can play together and are at utmost brought into play drug effect, can effectively improve the self-coordination ability of patient's body, significantly improve function and clinical subjective symptoms, have advantage such as have no side effect, expense is lower in addition.
The specific embodiment
Further describe the present invention by the following examples, it should be understood that these embodiment only are used for the purpose of illustration, never are limited to the present invention.
The preparation of [embodiment 1] capsule
Take by weighing each raw material by following weight portion: 15 parts of Radix Et Rhizoma Rhei, 50 parts of Pericarpium Citri Reticulataes, 20 parts of Radix Aucklandiae (Radix Vladimiriae), 30 parts of Rhizoma Cyperi, 20 parts of Lignum Dalbergiae Odoriferaes, 10 parts of Lignum Aquilariae Resinatum, 20 parts of Herba Lysimachiae foenum-graeci, 20 parts of Styrax, 20 parts of Benzoinumes, 20 parts of 15 parts of Calyx Kaki of Fructus Cannabis, 20 parts of Radix Angelicae Sinensis, 20 parts of the Radix Paeoniae Albas, 30 parts of Radix Trichosanthis, 50 parts of Rhizoma Acori Graminei, 10 parts of Borneolum Syntheticums, 10 parts of Camphoras, 5 parts of Venenum Bufoniss, 15 parts in Rhizoma Gastrodiae, 15 parts of Eupolyphaga Seu Steleophagas, 15 parts of Magnetitums, 10 parts of succinums, 15 parts in Cinnabaris, process 15 parts of Squama Manis, 15 parts of Rhizoma Chuanxiongs, 15 parts of Ramulus Cinnamomi, 20 parts of Rhizoma Corydalis, 20 parts in Rhizoma Curcumae Longae, 10 parts of Olibanum (processed), 10 parts of Myrrha (processed)s, 50 parts of Fructus Aurantii Immaturuss, 30 parts of Fructus Toosendans, 20 parts of Fructus Citri Sarcodactylis, 15 parts of Aspongopuss, 15 parts of Massa Medicata Fermentata, 15 parts of Semen Raphanis, 10 parts of Semen Prunis, 15 parts of Fructus Amomis, 10 parts of Cortex Magnoliae Officinalis, 10 parts of Rhizoma Atractylodis, 15 parts of Bulbus Allii Macrostemonis, 15 parts of Aloes, 15 parts of rhizoma sparganic, 15 parts of Rhizoma Curcumae, 15 parts of Radix Salviae Miltiorrhizaes, 10 parts on Flos Carthami, 10 parts in Semen Persicae, 10 parts of Flos Rosae Rugosaes.
Grind into after each component mixing with above-mentioned weight and incapsulate promptly after fine powder is crossed 1500 mesh sieves.
The preparation of [embodiment 2] granule
Take by weighing each raw material by following weight portion: 15 parts of Radix Et Rhizoma Rhei, 50 parts of Pericarpium Citri Reticulataes, 20 parts of Radix Aucklandiae (Radix Vladimiriae), 30 parts of Rhizoma Cyperi, 20 parts of Lignum Dalbergiae Odoriferaes, 10 parts of Lignum Aquilariae Resinatum, 20 parts of Herba Lysimachiae foenum-graeci, 20 parts of Styrax, 20 parts of Benzoinumes, 20 parts of 15 parts of Calyx Kaki of Fructus Cannabis, 20 parts of Radix Angelicae Sinensis, 20 parts of the Radix Paeoniae Albas, 30 parts of Radix Trichosanthis, 50 parts of Rhizoma Acori Graminei, 10 parts of Borneolum Syntheticums, 10 parts of Camphoras, 5 parts of Venenum Bufoniss, 15 parts in Rhizoma Gastrodiae, 15 parts of Eupolyphaga Seu Steleophagas, 15 parts of Magnetitums, 10 parts of succinums, 15 parts in Cinnabaris, process 15 parts of Squama Manis, 15 parts of Rhizoma Chuanxiongs, 15 parts of Ramulus Cinnamomi, 20 parts of Rhizoma Corydalis, 20 parts in Rhizoma Curcumae Longae, 10 parts of Olibanum (processed), 10 parts of Myrrha (processed)s, 50 parts of Fructus Aurantii Immaturuss, 30 parts of Fructus Toosendans, 20 parts of Fructus Citri Sarcodactylis, 15 parts of Aspongopuss, 15 parts of Massa Medicata Fermentata, 15 parts of Semen Raphanis, 10 parts of Semen Prunis, 15 parts of Fructus Amomis, 10 parts of Cortex Magnoliae Officinalis, 10 parts of Rhizoma Atractylodis, 15 parts of Bulbus Allii Macrostemonis, 15 parts of Aloes, 15 parts of rhizoma sparganic, 15 parts of Rhizoma Curcumae, 15 parts of Radix Salviae Miltiorrhizaes, 10 parts on Flos Carthami, 10 parts in Semen Persicae, 10 parts of Flos Rosae Rugosaes.
Each raw material of above-mentioned weight fraction is mixed, after grinding into fine powder and crossing 1500 mesh sieves, add ethanol and make adhesive, add starch and do filler, be pressed into granule.
The preparation of [embodiment 3] tablet
Take by weighing each raw material by following weight portion: 15 parts of Radix Et Rhizoma Rhei, 50 parts of Pericarpium Citri Reticulataes, 20 parts of Radix Aucklandiae (Radix Vladimiriae), 30 parts of Rhizoma Cyperi, 20 parts of Lignum Dalbergiae Odoriferaes, 10 parts of Lignum Aquilariae Resinatum, 20 parts of Herba Lysimachiae foenum-graeci, 20 parts of Styrax, 20 parts of Benzoinumes, 20 parts of 15 parts of Calyx Kaki of Fructus Cannabis, 20 parts of Radix Angelicae Sinensis, 20 parts of the Radix Paeoniae Albas, 30 parts of Radix Trichosanthis, 50 parts of Rhizoma Acori Graminei, 10 parts of Borneolum Syntheticums, 10 parts of Camphoras, 5 parts of Venenum Bufoniss, 15 parts in Rhizoma Gastrodiae, 15 parts of Eupolyphaga Seu Steleophagas, 15 parts of Magnetitums, 10 parts of succinums, 15 parts in Cinnabaris, process 15 parts of Squama Manis, 15 parts of Rhizoma Chuanxiongs, 15 parts of Ramulus Cinnamomi, 20 parts of Rhizoma Corydalis, 20 parts in Rhizoma Curcumae Longae, 10 parts of Olibanum (processed), 10 parts of Myrrha (processed)s, 50 parts of Fructus Aurantii Immaturuss, 30 parts of Fructus Toosendans, 20 parts of Fructus Citri Sarcodactylis, 15 parts of Aspongopuss, 15 parts of Massa Medicata Fermentata, 15 parts of Semen Raphanis, 10 parts of Semen Prunis, 15 parts of Fructus Amomis, 10 parts of Cortex Magnoliae Officinalis, 10 parts of Rhizoma Atractylodis, 15 parts of Bulbus Allii Macrostemonis, 15 parts of Aloes, 15 parts of rhizoma sparganic, 15 parts of Rhizoma Curcumae, 15 parts of Radix Salviae Miltiorrhizaes, 10 parts on Flos Carthami, 10 parts in Semen Persicae, 10 parts of Flos Rosae Rugosaes.
Each raw material of above-mentioned weight portion is mixed, after grinding into fine powder and crossing 800~1200 order dusting covers, make tablet promptly.
The preparation of [embodiment 4] pill
Take by weighing each raw material by following weight portion: 15 parts of Radix Et Rhizoma Rhei, 50 parts of Pericarpium Citri Reticulataes, 20 parts of Radix Aucklandiae (Radix Vladimiriae), 30 parts of Rhizoma Cyperi, 20 parts of Lignum Dalbergiae Odoriferaes, 10 parts of Lignum Aquilariae Resinatum, 20 parts of Herba Lysimachiae foenum-graeci, 20 parts of Styrax, 20 parts of Benzoinumes, 20 parts of 15 parts of Calyx Kaki of Fructus Cannabis, 20 parts of Radix Angelicae Sinensis, 20 parts of the Radix Paeoniae Albas, 30 parts of Radix Trichosanthis, 50 parts of Rhizoma Acori Graminei, 10 parts of Borneolum Syntheticums, 10 parts of Camphoras, 5 parts of Venenum Bufoniss, 15 parts in Rhizoma Gastrodiae, 15 parts of Eupolyphaga Seu Steleophagas, 15 parts of Magnetitums, 10 parts of succinums, 15 parts in Cinnabaris, process 15 parts of Squama Manis, 15 parts of Rhizoma Chuanxiongs, 15 parts of Ramulus Cinnamomi, 20 parts of Rhizoma Corydalis, 20 parts in Rhizoma Curcumae Longae, 10 parts of Olibanum (processed), 10 parts of Myrrha (processed)s, 50 parts of Fructus Aurantii Immaturuss, 30 parts of Fructus Toosendans, 20 parts of Fructus Citri Sarcodactylis, 15 parts of Aspongopuss, 15 parts of Massa Medicata Fermentata, 15 parts of Semen Raphanis, 10 parts of Semen Prunis, 15 parts of Fructus Amomis, 10 parts of Cortex Magnoliae Officinalis, 10 parts of Rhizoma Atractylodis, 15 parts of Bulbus Allii Macrostemonis, 15 parts of Aloes, 15 parts of rhizoma sparganic, 15 parts of Rhizoma Curcumae, 15 parts of Radix Salviae Miltiorrhizaes, 10 parts on Flos Carthami, 10 parts in Semen Persicae, 10 parts of Flos Rosae Rugosaes.
Each raw material of above-mentioned weight is mixed, grind into cross 600~1000 mesh sieves behind the fine powder after, make pill promptly.
The preparation of [embodiment 5] oral liquid
Take by weighing each raw material by following weight portion: 15 parts of Radix Et Rhizoma Rhei, 50 parts of Pericarpium Citri Reticulataes, 20 parts of Radix Aucklandiae (Radix Vladimiriae), 30 parts of Rhizoma Cyperi, 20 parts of Lignum Dalbergiae Odoriferaes, 10 parts of Lignum Aquilariae Resinatum, 20 parts of Herba Lysimachiae foenum-graeci, 20 parts of Styrax, 20 parts of Benzoinumes, 20 parts of 15 parts of Calyx Kaki of Fructus Cannabis, 20 parts of Radix Angelicae Sinensis, 20 parts of the Radix Paeoniae Albas, 30 parts of Radix Trichosanthis, 50 parts of Rhizoma Acori Graminei, 10 parts of Borneolum Syntheticums, 10 parts of Camphoras, 5 parts of Venenum Bufoniss, 15 parts in Rhizoma Gastrodiae, 15 parts of Eupolyphaga Seu Steleophagas, 15 parts of Magnetitums, 10 parts of succinums, 15 parts in Cinnabaris, process 15 parts of Squama Manis, 15 parts of Rhizoma Chuanxiongs, 15 parts of Ramulus Cinnamomi, 20 parts of Rhizoma Corydalis, 20 parts in Rhizoma Curcumae Longae, 10 parts of Olibanum (processed), 10 parts of Myrrha (processed)s, 50 parts of Fructus Aurantii Immaturuss, 30 parts of Fructus Toosendans, 20 parts of Fructus Citri Sarcodactylis, 15 parts of Aspongopuss, 15 parts of Massa Medicata Fermentata, 15 parts of Semen Raphanis, 10 parts of Semen Prunis, 15 parts of Fructus Amomis, 10 parts of Cortex Magnoliae Officinalis, 10 parts of Rhizoma Atractylodis, 15 parts of Bulbus Allii Macrostemonis, 15 parts of Aloes, 15 parts of rhizoma sparganic, 15 parts of Rhizoma Curcumae, 15 parts of Radix Salviae Miltiorrhizaes, 10 parts on Flos Carthami, 10 parts in Semen Persicae, 10 parts of Flos Rosae Rugosaes.
Each raw material of above-mentioned weight is mixed, after three decoctions, three filtrates are mixed, filter, be concentrated into
The regulation concentration, put cold, the stock solution embedding, irradiation sterilization, after the check, packed products is made oral liquid promptly.
The preparation of [embodiment 6] powder
Take by weighing each raw material by following weight portion: 15 parts of Radix Et Rhizoma Rhei, 50 parts of Pericarpium Citri Reticulataes, 20 parts of Radix Aucklandiae (Radix Vladimiriae), 30 parts of Rhizoma Cyperi, 20 parts of Lignum Dalbergiae Odoriferaes, 10 parts of Lignum Aquilariae Resinatum, 20 parts of Herba Lysimachiae foenum-graeci, 20 parts of Styrax, 20 parts of Benzoinumes, 20 parts of 15 parts of Calyx Kaki of Fructus Cannabis, 20 parts of Radix Angelicae Sinensis, 20 parts of the Radix Paeoniae Albas, 30 parts of Radix Trichosanthis, 50 parts of Rhizoma Acori Graminei, 10 parts of Borneolum Syntheticums, 10 parts of Camphoras, 5 parts of Venenum Bufoniss, 15 parts in Rhizoma Gastrodiae, 15 parts of Eupolyphaga Seu Steleophagas, 15 parts of Magnetitums, 10 parts of succinums, 15 parts in Cinnabaris, process 15 parts of Squama Manis, 15 parts of Rhizoma Chuanxiongs, 15 parts of Ramulus Cinnamomi, 20 parts of Rhizoma Corydalis, 20 parts in Rhizoma Curcumae Longae, 10 parts of Olibanum (processed), 10 parts of Myrrha (processed)s, 50 parts of Fructus Aurantii Immaturuss, 30 parts of Fructus Toosendans, 20 parts of Fructus Citri Sarcodactylis, 15 parts of Aspongopuss, 15 parts of Massa Medicata Fermentata, 15 parts of Semen Raphanis, 10 parts of Semen Prunis, 15 parts of Fructus Amomis, 10 parts of Cortex Magnoliae Officinalis, 10 parts of Rhizoma Atractylodis, 15 parts of Bulbus Allii Macrostemonis, 15 parts of Aloes, 15 parts of rhizoma sparganic, 15 parts of Rhizoma Curcumae, 15 parts of Radix Salviae Miltiorrhizaes, 10 parts on Flos Carthami, 10 parts in Semen Persicae, 10 parts of Flos Rosae Rugosaes.
Grinding into fine powder after each component of above-mentioned weight mixed crosses behind 600 mesh sieves promptly.
[experimental example] traditional Chinese medicine composition for treating cancer of the esophagus of the present invention patient's clinical observation on the therapeutic effect experiment
One, the physical data of experimental subject: adopt Chinese medicine composition of the present invention to treat 56 routine patients altogether, wherein male 39 examples, women 17 examples; The oldest person 75 years old, the age reckling has only 1 years old.
Two, Therapeutic Method:
Usage and dosage: adopt the prepared medicament of the embodiment of the invention, its usage and consumption are as follows: 1) capsule: obey 2~5 every day three times at every turn, and every content of dispersion 0.4 gram, warm water takes.2) tablet: every day three times, each 2~4, every content of dispersion 0.5 gram, warm water takes.3) pill: every day three times, each 5 grams, warm water takes.4) granule: every day three times.Each 5 grams, warm water takes.5) powder: every day three times, each 3~5 grams, warm water takes.
The course of treatment: a week is a course of treatment, treats for 4 courses of treatment altogether.
Three, therapeutic evaluation standard
Cure: sign and symptom are improved fully, and be happy, in high spirits.
Produce effects: sign and symptom are significantly improved, and be happy, and spirit is fine.
Effectively: sign and symptom change, and random thoughts have discomfort slightly, but can accept.
Invalid: sign does not have change, symptom such as preceding.
Four, model case:
1, the week certain, woman, 51 years old, cadre.
The patient is onset before 4 years, and is sick preceding because of often depression of family matters, singultus when having a meal of being everlasting then, and it is surplus to continue about l month.After this self-induction food blocks at the breastbone rear portion, dysphagia, and having a meal to need to dash with boiled water gulps down just and can swallow, and symptom increases the weight of gradually, even repeatedly kicks into the semi-fluid gruel of food and also feel dysphagia, as swallowing i.e. vomiting reluctantly.Through for oral administration Chinese medicine and western medicine, acupuncture, physical therapy, treatment such as sunken cord, there is no significant curative effect, the state of an illness is lasted 3 years repeatedly.Examine and see: health is become thin, and nutritional status is relatively poor, tired mind, emotion gloom, red tongue, clean no fur, stringy and thready pulse.
Took Chinese medicine composition of the present invention 3, the conscious food sense of obstruction of swallowing significantly alleviates, and only singultus occurs accidentally in 3 days, the gruel of can taking food, and mood is also rather happy.The clothes Chinese medicine composition of the present invention 15 days that continues, the patient is full of joy, states to swallow the food sense of obstruction and disappear, there has not been sense of obstruction during feed behind the breastbone, more not having vomiting, gulp down, breakfast, lunch and dinner appetite every day (totally 8 liang) as usual though the common food of taking food can send without boiled water. defecation is all normal.For consolidating curative effect.The clothes Chinese medicine composition of the present invention 10 days that continues, recovery from illness was followed up a case by regular visits to after 4 years, and patient's daily life, things are as usual in work, weight increase.
2, Shen, woman, 43 years old, artist.
The patient swallowed the dysphagia sense over 2 years during feed, often need companion's drink soup beginning food can be swallowed, but influent stream matter also can not be swallowed smoothly.Sometimes spue and feel comfortably cool after the food.Low pillow is put down and is glowed food and water liquid when crouching.Lower esophageal dull pain then can be ended behind the drink boiled water bitterly.Sometimes belch, the delegation on the 2nd~3 of defecating.Thin fur, arteries and veins is than stringy and rolling pulse.
Took Chinese medicine composition of the present invention 3, and told the unable 150g of every meal, swallow and more precedingly swallow but still need drink soup sometimes smoothly, low pillow is flat only to glow water liquid when crouching and not to glow food, and last night, clear water did not also glow, stool every other day row.The clothes Chinese medicine composition of the present invention 7 days that continues is swallowed obvious improvement, eats in meal, can send down without soup, but swallow slowlyer, and low pillow is flat when crouching, and no food and clear water are counter to flow, and defecates and asks a day delegation.Continue and obeyed Chinese medicine composition of the present invention 7, the feed idol has dysphagia, and a small amount of soup can be swallowed, and sternal end has not had pain, and transference cure is received just as usual, clinical no abnormal.
3, Zhang, woman, 29 years old, accounting.
Dysphagia, in time, weigh more than 2 years when light.Once once took effect with Western medicine earlier, and again again as before, cooperated Chinese medicine dispersing the stagnated pathogen with pungent drugs and lowering the adverse QI with bitter drugs, stopping nausea and vomiting by lowering the adverse flow of QI again, regulate the flow of vital energy treatments such as opening diaphragm more than 1 year after the week, disease does not subtract.The state of an illness is more serious over particularly past 3~4 months, under the dysphagia difficulty of having a meal ninety-nine times out of a hundred, drink water all, and vomiting and going out.And see indigestion and loss of appetite decreased food intake, fatigue and weak, thin white fur of tongue, deficient and large pulse.
Took Chinese medicine composition of the present invention 5, all diseases all alleviate.The clothes Chinese medicine composition of the present invention 10 days that continues, dysphagia is further improved, and not only do not see and tell medicine, and vomiting food, dysphagia subtracts greatly, and diet increases, and spirit is gradually shaken.Continue and obeyed Chinese medicine composition of the present invention 10, symptom all disappears, and follows up a case by regular visits to normal after 2 years.
4, Lee, woman, 23 years old, student.
The patient is the discontinuity dysphagia over nearly 1 year, taking food, more the slag thing is arranged is the regurgitation vomiting and nausea, nocturnal cough, salivation, the surgery Esophagomyotomy of once going is treated, and the postoperative symptom is not alleviated, the regurgitation vomiting and nausea is done frequently, the time the not digest food that spues, the sticky odorless of matter, disease is seen pale complexion, light red tongue, white, slippery and moist fur, deep-rolling pulse.
Took Chinese medicine composition of the present invention 5, dysphagia is improved, and can eat some has slag food, and regurgitation vomiting idol is done.The clothes Chinese medicine composition of the present invention 5 days that continues, dysphagia is further improved, and cough, salivation end, and appetite increases, and spirit takes a turn for the better, the clothes Chinese medicine composition of the present invention 15 days of continuing, all diseases are removed entirely, and the patient has rosy cheeks, weight increase, it is normal that life study all recovers.
5, Jiang, man, 27 years old, workman.
The patient is just very difficult from eating for a short time, can only bit by bit eat, and has some and will firmly swallow.The thing of eating kecks, and just can spue at once again.Esophagus detecting is found: the esophagus the inside has been full of water sample liquid, when arriving the stomachus cardiacus position that esophagus is connected with stomach, and small amounts of food residue in addition.Examine and see patient's dysphagia, the chest and diaphragm feeling of fullness, vomiting food or sputum, the anorexia loose stool, spiritlessness and weakness, deficiency of QI with disinclination to talk, emaciated physique, pale tongue with thin fur is white, thready and weak pulse or deep and slow.
Took Chinese medicine composition of the present invention 5, the more preceding remarkable alleviation of symptom, vomiting ends.Continue and obeyed Chinese medicine composition of the present invention 10, dysphagia is significantly improved, and appetite heightens, and spirit is gradually shaken.Continue and obeyed Chinese medicine composition of the present invention 10, symptom all disappears, and the patient is in high spirits, 6 kilograms of weight increase, and life is normal.
6, grandson, woman, 50 years old, teacher.
1 wheat harvesting period comes, dysphagia in the conscious process of having a meal, and certain doctor opens diaphragm, leads to treatment l Zhou Buxiao such as deep and remote with Chinese medicine.Use western medicine again instead, after 2 weeks, the state of an illness increases the weight of.The difficulty of dripping is advanced, the sticking saliva of vomiting constantly, and vexed uneasiness must not be fallen asleep round the clock, extremely become thin (body weight 3l kilogram).Shortness of breath and fatigue, dysphoria, thin white fur of tongue, deep-slow pulse are sliding slightly.
Took Chinese medicine composition of the present invention 3, the beginning of taking medicine, the every pharynx a bite medicine juice i.e. overwhelming majority is vomitted and is gone out, to taking one when boiling medicine, medicine juice promptly can major part be swallowed in stomach, when taking the 3rd, not only can swallow medicine juice smoothly, and the Lac Bovis seu Bubali of can taking food, rare noodles, fine dried noodles etc.Continue and obeyed Chinese medicine composition of the present invention 10, appetite heightens, and can eat 350~400 gram foods every day, and can eat steamed bread, pancake etc.Continue and obeyed Chinese medicine composition of the present invention 15, all cards disappear, 10 kilograms of weight increase, working work.
7, money so-and-so, man, 38 years old, office worker.
It is down difficult to swallow, even promptly tell more than 5 years after the food.Once once took a turn for the better earlier, but promptly invalid soon, cooperated the Chinese medicine stopping nausea and vomiting by lowering the adverse flow of QI again, the medicines such as opening diaphragm, blood circulation promoting and blood stasis dispelling of regulating the flow of vital energy is controlled more than 3 years, is still beginning effectively, and is ineffective more thereafter for this reason with western medicine.Sift its card, feel under the dysphagia difficulty when swallowing the every distal esophagus of food, also occur occasionally promptly telling after the food, anabole is a food, no acid smell, and thin white fur of tongue, stringy and tense pulse are several slightly.
Took Chinese medicine composition of the present invention 3, and significantly alleviated under the diet dysphagia difficulty, nausea and vomiting greatly alleviates.Continue and obeyed Chinese medicine composition of the present invention 10, swallow difficult significantly alleviation down, promptly do not tell generation after the food, diet increases, and symptom is greatly taken on a new look.Continue and obeyed Chinese medicine composition of the present invention 10, all diseases are all removed, and patient's life and work is normal.
8, the king so-and-so, man, 70 years old, retired cadre.
Uncomfortable 1 year of gastral cavilty portion is surplus.Frequent nausea and vomiting, obvious with the nausea and vomiting of taking food when very fast especially, every day 4~5 times.Like warm pain relieved by pressing at ordinary times, like warm diet.The raw and cold food of taking food can bring out the above-mentioned symptom outbreak.5 kilograms of weight loss, thin white fur of tongue, pale tongue is dark, deep-slow pulse.Every inspection no abnormality seen.
Took Chinese medicine composition of the present invention 3, nausea and vomiting obviously alleviates, and only take place once every day, and abdomen does not expand.Continue and obeyed Chinese medicine composition of the present invention 15, vomiting disappears substantially, and idol has slight abdominal distention, and receiving can.The clothes Chinese medicine composition of the present invention 10 days that continues, symptom all disappears, and follows up a case by regular visits to stable disease, and weight increase does not occur uncomfortable in chest, chest pain and feed again and sends out the situation of choking.
Five, therapeutic outcome:
In the 56 routine cases of being accepted for medical treatment,, wherein cure 34 examples through the treatment of 4 weeks, produce effects 12 examples, effective 8 examples, invalid 2 examples, total effective rate reaches 96%.The result shows that Chinese medicine composition of the present invention has extremely significant curative effect to treatment cancer of the esophagus patient.

Claims (7)

1. Chinese medicine composition for the treatment of the cancer of the esophagus is characterized in that: mainly contain following bulk drugs and form:
1~50 part of Radix Et Rhizoma Rhei, 1~100 part of Pericarpium Citri Reticulatae, 1~100 part of Radix Aucklandiae (Radix Vladimiriae), 1~120 part of Rhizoma Cyperi, 1~100 part of Lignum Dalbergiae Odoriferae, 1~50 part of Lignum Aquilariae Resinatum, 1~100 part of Herba Lysimachiae foenum-graeci, 1~100 part of Styrax, 1~100 part of Benzoinum, 1~30 part of 1~50 part of Calyx Kaki of Fructus Cannabis, 1~100 part of Radix Angelicae Sinensis, 1~100 part of the Radix Paeoniae Alba, 1~100 part of Radix Trichosanthis, 1~150 part of Rhizoma Acori Graminei, 1~30 part of Borneolum Syntheticum, 1~30 part of Camphora, 1~20 part of Venenum Bufonis, 1~50 part in Rhizoma Gastrodiae, 1~50 part of Eupolyphaga Seu Steleophaga, 1~50 part of Magnetitum, 1~50 part of succinum, 1~50 part in Cinnabaris, process 1~50 part of Squama Manis, 1~50 part of Rhizoma Chuanxiong, 1~50 part of Ramulus Cinnamomi, 1~100 part of Rhizoma Corydalis, 1~100 part in Rhizoma Curcumae Longae, 1~50 part of Olibanum (processed), 1~50 part of Myrrha (processed), 1~120 part of Fructus Aurantii Immaturus, 1~100 part of Fructus Toosendan, 1~100 part of Fructus Citri Sarcodactylis, 1~50 part of Aspongopus, 1~100 part of Massa Medicata Fermentata.
, according to the described Chinese medicine composition of claim 1, it is characterized in that: the weight portion of each crude drug is:
15 parts of Radix Et Rhizoma Rhei, 50 parts of Pericarpium Citri Reticulataes, 20 parts of Radix Aucklandiae (Radix Vladimiriae), 30 parts of Rhizoma Cyperi, 20 parts of Lignum Dalbergiae Odoriferaes, 10 parts of Lignum Aquilariae Resinatum, 20 parts of Herba Lysimachiae foenum-graeci, 20 parts of Styrax, 20 parts of Benzoinumes, 20 parts of 15 parts of Calyx Kaki of Fructus Cannabis, 20 parts of Radix Angelicae Sinensis, 20 parts of the Radix Paeoniae Albas, 30 parts of Radix Trichosanthis, 50 parts of Rhizoma Acori Graminei, 10 parts of Borneolum Syntheticums, 10 parts of Camphoras, 5 parts of Venenum Bufoniss, 15 parts in Rhizoma Gastrodiae, 15 parts of Eupolyphaga Seu Steleophagas, 15 parts of Magnetitums, 10 parts of succinums, 15 parts in Cinnabaris, process 15 parts of Squama Manis, 15 parts of Rhizoma Chuanxiongs, 15 parts of Ramulus Cinnamomi, 20 parts of Rhizoma Corydalis, 20 parts in Rhizoma Curcumae Longae, 10 parts of Olibanum (processed), 10 parts of Myrrha (processed)s, 50 parts of Fructus Aurantii Immaturuss, 30 parts of Fructus Toosendans, 20 parts of Fructus Citri Sarcodactylis, 15 parts of Aspongopuss, 15 parts of Massa Medicata Fermentata.
, according to the described Chinese medicine composition of claim 1, wherein crude drug also has:
1~50 part of Semen Raphani, 1~50 part of Semen Pruni, 1~50 part of Fructus Schisandrae Chinensis, 1~50 part of Fructus Mume, 1~50 part of Fructus Crataegi, 1~50 part in Fructus Hordei Germinatus, 1~50 part of Endothelium Corneum Gigeriae Galli, 1~50 part of Fructus Amomi, 1~50 part of Cortex Magnoliae Officinalis, 1~50 part of Rhizoma Atractylodis, 1~50 part of Bulbus Allii Macrostemonis, 1~50 part of Aloe, 1~50 part of rhizoma sparganic, 1~50 part of Rhizoma Curcumae, 1~50 part of Radix Salviae Miltiorrhizae, 1~50 part on Flos Carthami, 1~50 part in Semen Persicae, 1~50 part of Flos Rosae Rugosae, 1~50 part of Bombyx Batryticatus, 1~50 part of Caulis Spatholobi.
4. according to the described Chinese medicine composition of claim 3, wherein the weight portion of each component is:
15 parts of Semen Raphanis, 10 parts of Semen Prunis, 10 parts of Fructus Schisandrae Chinensis, 10 parts of Fructus Mumes, 10 parts of Fructus Crataegis, 15 parts in Fructus Hordei Germinatus, 15 parts of Endothelium Corneum Gigeriae Galli, 15 parts of Fructus Amomis, 10 parts of Cortex Magnoliae Officinalis, 10 parts of Rhizoma Atractylodis, 15 parts of Bulbus Allii Macrostemonis, 15 parts of Aloes, 15 parts of rhizoma sparganic, 15 parts of Rhizoma Curcumae, 15 parts of Radix Salviae Miltiorrhizaes, 10 parts on Flos Carthami, 10 parts in Semen Persicae, 10 parts of Flos Rosae Rugosaes, 15 parts of Bombyx Batryticatus, 15 parts of Caulis Spatholobis.
5. according to claim 1,2,3 or 4 described any Chinese medicine compositions, it is characterized in that: can be prepared into any oral formulations commonly used according to the method for Chinese medicinal of routine.
6. according to the described Chinese medicine composition of claim 5, it is characterized in that: described oral formulations is pill, capsule, tablet, powder, granule or oral liquid.
7. the application of the described any Chinese medicine composition of claim 1~6 in preparation treatment cancer of the esophagus medicine.
CN2010101542235A 2010-04-23 2010-04-23 Chinese medicinal composition for treating hiccup and preparation method thereof Expired - Fee Related CN101874888B (en)

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103349726A (en) * 2013-06-24 2013-10-16 朱颖 Traditional Chinese medicine for treating hiccup
CN104083043A (en) * 2014-06-30 2014-10-08 南通蛇类治疗研究所 Medicine pillow capable of arousing brain, reducing pressure, preventing paralysis and dementia, promoting sleep and being beneficial to longevity
CN105535869A (en) * 2016-02-16 2016-05-04 成都富豪斯生物科技有限公司 Traditional Chinese medicine composition capable of effectively treating dysphagia and preparation method thereof

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1105575A (en) * 1994-03-03 1995-07-26 王申 Dysphagia ointment and its preparation method
CN1231915A (en) * 1998-11-23 1999-10-20 刘正全 Pill for treatment of esophagus cancer
CN1813967A (en) * 2005-02-02 2006-08-09 边丙顺 Chinese medicine remedy for treating cancer of alimentany tract

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1105575A (en) * 1994-03-03 1995-07-26 王申 Dysphagia ointment and its preparation method
CN1231915A (en) * 1998-11-23 1999-10-20 刘正全 Pill for treatment of esophagus cancer
CN1813967A (en) * 2005-02-02 2006-08-09 边丙顺 Chinese medicine remedy for treating cancer of alimentany tract

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103349726A (en) * 2013-06-24 2013-10-16 朱颖 Traditional Chinese medicine for treating hiccup
CN103349726B (en) * 2013-06-24 2014-12-10 青岛大学附属医院 Traditional Chinese medicine for treating hiccup
CN104083043A (en) * 2014-06-30 2014-10-08 南通蛇类治疗研究所 Medicine pillow capable of arousing brain, reducing pressure, preventing paralysis and dementia, promoting sleep and being beneficial to longevity
CN104083043B (en) * 2014-06-30 2016-03-02 南通蛇类治疗研究所 The silly short dormancy of the anti-paralysis of brain clearing and blood pressure reducing lengthens one's life medicine-filled pillow
CN105535869A (en) * 2016-02-16 2016-05-04 成都富豪斯生物科技有限公司 Traditional Chinese medicine composition capable of effectively treating dysphagia and preparation method thereof

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