CN101869700A - Chinese medicinal oral liquid for treating tumour and preparation method thereof - Google Patents
Chinese medicinal oral liquid for treating tumour and preparation method thereof Download PDFInfo
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Abstract
The invention relates to Chinese medicinal oral liquid for treating tumour and a preparation method thereof. The oral liquid is prepared from the following raw materials by weight: 2 to 6 milligrams of sodium cantharidinate, 1 to 3 milligrams of scorpion venom, 4 to 6 grams of gecko essence, 40 to 60 milligrams of hirudin, 17 to 50 micrograms of organic selenium, 9 to 15 grams of rhizoma paridis water extract, 6 to 13 grams of panax ginseng water extract, 15 to 30 grams of large-headed atractylodes rhizome water extract and 20 to 40 grams of astragalus water extract. The preparation method comprises the following steps of: weighing the sodium cantharidinate, the scorpion venom, the gecko essence, the hirudin, the organic selenium, the rhizoma paridis water extract, the panax ginseng water extract, the large-headed atractylodes rhizome water extract, the astragalus water extract and suberect spatholobus stem water extract respectively, and mixing the materials uniformly in a weight ratio. On the one hand, the Chinese medicinal oral liquid can kill cancer cells, eliminate phyma and remove pathological products such as phlegm, dampness, ecehymosis, toxicity and the like, and on the other hand, the Chinese medicinal oral liquid has the effects of assisting vital qi, improving physical quality, enhancing the capability of immunity and disease resistance capability, prolonging the survival time and improving the survival quality. Through the clinical observation, the Chinese medicinal oral liquid has 85 percent of effective rate and has quick response and good curative effect on patients who suffer from cancer in alimentary systems and respiratory systems.
Description
Technical field
The invention belongs to medical technical field, be specifically related to a kind of Chinese medicine oral liquid for the treatment of tumor and preparation method thereof.
Background technology
The oncotherapy scheme is at present: operation, radiotherapy, chemotherapy, immunity, Chinese medicine.The operation of doctor trained in Western medicine can be excised the carcinoma entity rapidly, and this is that Chinese medicine is incomparable, but operation residual limbs of having separated will on the one hand live for the patient from now on and increased many difficulties, has many patients to recur in several months or several years or shift on the other hand again.Though the putting of doctor trained in Western medicine, chemotherapy have great role to killing cancerous cell, side effect is also very big, and patient's body constitution is descended rapidly, has reduced quality of life.Experimentation shows, not only can not treat some cancer operation excision, and the danger that promotes cancerous cell to be fulminant growing multiplication and transfer is arranged on the contrary.What the traditional Chinese medical science was thought cancer is viscera, meridians, negative and positive, disorder of QI and blood, under the multifactor effects such as seven emotions, six desires, diet, overstrain, wound, cause that blood stasis, expectorant coagulate, accumulate in the pyretic toxicity, a series of pathogenesis such as healthy energy loss change, expectorant, the stagnant pyretic toxicity that with the passing of time produces of the stasis of blood, the rich knot of poison blood stasis, the turbid caking of expectorant and form cancer, just different titles has just been arranged on doctor trained in Western medicine, and traditional Chinese medical science Tong Cheng is a lumps in the chest and abdomen because the source is different with growth site.The conditioning and the Therapeutic Method of traditional Chinese medical science uniqueness are accepted by tumor patient just gradually at present.The overwhelming majority is the pathological changes of a certain position of treatment or system in the method for numerous Chinese traditional treatment tumors, and has just had no way of doing it after the tumor long range diffusion shifts.And mostly contain hypertoxic composition in the great majority prescription at present, though the treating the poisonous disease with poisonous drugs method is effective to the treatment tumor, human body there is big side effect.
Summary of the invention
The invention provides a kind of Chinese medicine oral liquid for the treatment of tumor and preparation method thereof, with medicine dispersing pathogen accumulations such as Mylabris, scorpion venom, Gekko Swinhonis, Hirudo, Rhizoma Paridis, the nucleic acid of anticancer and protein form, the division and proliferation of containment tumor cell, suppress the further increase of tumor, and cut off the energy supply of tumor cell, make existing tumor cell because of energy drain atrophy death gradually.Scorpion venom also has analgesic effect.Mylabris can also stimulate bone marrow, causes that leukocyte raises the human activin immune system.Extraction derivant disodium cantharidinate with Mylabris substitutes Mylabris, and experiment shows that their pharmacological action is similar, but toxicity is much smaller than Mylabris.Human body is made of multiple element, and wherein trace element is the most basic nutrient of human body, and trace element is can not be synthetic voluntarily in vivo.Have 88% from food in the various trace elements of taking in every day of being grown up according to statistics, the disease that sickness rate is the highest among the crowd, influence is the widest the unbalance of trace element just causes.The human body trace elements necessary has 25 kinds more than, as selenium, germanium, tungsten, cobalt, manganese, molybdenum, chromium, zinc, magnesium, copper, ferrum, iodine etc.The intravital blood Se content of cancer patient is lower 3～6 times than the normal person according to the survey; selenium not only can form the interior environment of anticancer division and propagation in human body; play the effect that anticancer increases; and selenium does not only have inhibitory action that the certain protection effect is arranged on the contrary to human normal cell's growth under the same conditions; particularly under weary oxygen condition; this protective effect is more outstanding; selenium can be induced differentiation; impel cancerous cell " to turn over a new leaf "; and the targeting inhibitory or killing effect is arranged, " heresy " removed and do not hindered " just ".Be rich in the needed by human body trace element in the Gekko Swinhonis; be equipped with again and can be the organic selenium that human body absorbs rapidly; balance and satisfy needed by human body gradually just; make tumor tissues lose due living environment; and the protection normal cell; the immune system that makes cancer patient be in " dormancy " state recovers normal, suppresses the transfer of tumor cell, improves patient's resistivity.Gekko Swinhonis is for a kind of safely and effectively in the present antitumor drug.With Radix Ginseng, the Rhizoma Atractylodis Macrocephalae, the Radix Astragali, Caulis Spatholobi, Radix Glycyrrhizae Preparata vital base and primordial QI consolidating, set upright and press down evilly, reduce and send an expedition against medicine the infringement of the damage of human body and malignant tumor pathological changes to human body.They itself just have antitumor action, also are the antitumor synergists simultaneously.The Radix Ginseng stimulating immune system improves phagocytic activity; The Radix Astragali, Radix Glycyrrhizae Preparata can protect the liver; The Radix Astragali, Caulis Spatholobi increase hemocyte; The Radix Astragali, the Rhizoma Atractylodis Macrocephalae, Caulis Spatholobi all have diuresis, but the toxin expelling diuretic, so take the fraud of not having the savings poisoning for a long time.The present invention adopts the spissated method of purifying that the active ingredient in the Chinese medicine is extracted, taking convenience is evident in efficacy, especially for the patient of esophageal carcinoma one class, has solved the take medicine problem of difficulty of patient.
Oral liquid of the present invention is made by the raw material of following weight ratio: disodium cantharidinate 2～6mg, scorpion venom 1～3mg, Gekko Swinhonis element 4～6g, hirudin 40～60mg, organic selenium 17～50 μ g, Rhizoma Paridis water extract 9～15g, ginseng aqueous extract 6～13g, Rhizoma Atractylodis Macrocephalae water extract 15～30g, water extraction of astragalus membranaceus 20～40g, Caulis Spatholobi water extract 20～30g.
Be added with the raw material of following weight ratio in the described oral liquid: Radix Glycyrrhizae Preparata water extract is 6～10g.
The present invention has the effect of strengthening the body resistance, heat-clearing and toxic substances removing, dispersing swelling and dissipating binds, removing obstruction in the collateral to relieve pain.It can be discerned paraplasm tumor cell, locks target cell then, makes the effect of medicine fixed point, the division and proliferation of containment tumor cell; Simultaneously fully the human activin immune system impels immunocyte to breed in a large number, assembles around tumor cell by the chemotactic motion, engulfs and induces the differentiation tumor cell, impels it to reverse to normal cell.Because this medical instrument has target function, so normal cell is had no side effect.And this therapeutic process all disappears until target cell reaching under the effective blood drug concentration state and can carrying out repeatedly.Obtained better therapeutic effect at present, effective percentage reaches 85%, and is fast to the digestive system and respiratory system produce effects especially, and the 7 days patients that generally take medicine will subjective symptoms alleviate.Except oral, the present invention also has some special usings method, and the patient who suffers from superficial tumors such as breast carcinoma, lymphatic cancer such as some can be oral on one side, simultaneously medicinal liquid soaked the outer affected part that spreads on absorbent cotton, the energy alleviating pain also has therapeutical effect on the other hand on the one hand.In oral, can put into nebulizer after the medicinal liquid 2ml dilution if suffer from patient's conditions permit of pulmonary carcinoma, reach the effect of external application by the atomizing suction, thereby obtain curative effect better.But the present invention is invalid to leukemia (leukemia), and it is because medulla hematopoietic system has and cancerates, but not the common lump in the traditional Chinese medical science notion.
Preparation method one of the present invention:
A, preparation Gekko Swinhonis element: get the Gekko Swinhonis dry product and pulverize an amount of soaked in absolute ethyl alcohol twice of back adding, filter, twice filtrate is merged the back concentrate;
B, preparation organic selenium: get dried Folium Fici pulverizing back and add the suitable quantity of water dipping three times, filter, three filtrates merging backs are concentrated;
C, prepare Rhizoma Paridis water extract, ginseng aqueous extract, Rhizoma Atractylodis Macrocephalae water extract, water extraction of astragalus membranaceus and Caulis Spatholobi water extract respectively;
D, take by weighing disodium cantharidinate, scorpion venom, Gekko Swinhonis element, hirudin, organic selenium, Rhizoma Paridis water extract, ginseng aqueous extract, Rhizoma Atractylodis Macrocephalae water extract, water extraction of astragalus membranaceus and Caulis Spatholobi water extract respectively and get final product by described weight ratio mix homogeneously.
Preparation method two of the present invention:
A, preparation Gekko Swinhonis element: get the Gekko Swinhonis dry product and pulverize an amount of soaked in absolute ethyl alcohol twice of back adding, filter, twice filtrate is merged the back concentrate;
B, preparation organic selenium: get dried Folium Fici pulverizing back and add the suitable quantity of water dipping three times, filter, three filtrates merging backs are concentrated;
C, prepare Rhizoma Paridis water extract, ginseng aqueous extract, Rhizoma Atractylodis Macrocephalae water extract, water extraction of astragalus membranaceus, Caulis Spatholobi water extract and Radix Glycyrrhizae Preparata water extract respectively;
D, take by weighing disodium cantharidinate, scorpion venom, Gekko Swinhonis element, hirudin, organic selenium, Rhizoma Paridis water extract, ginseng aqueous extract, Rhizoma Atractylodis Macrocephalae water extract, water extraction of astragalus membranaceus, Caulis Spatholobi water extract and Radix Glycyrrhizae Preparata water extract respectively and get final product by described weight ratio mix homogeneously.
The preparation technology of described Rhizoma Atractylodis Macrocephalae water extract: get and add suitable quantity of water after Rhizoma Atractylodis Macrocephalae dry product is pulverized and soak once, filter, filtrate is stand-by, and filtering residue adds suitable quantity of water again and decocts secondary filter, will three filtrates merges the back and concentrates;
The preparation technology of described Rhizoma Paridis water extract, ginseng aqueous extract, water extraction of astragalus membranaceus and Caulis Spatholobi water extract: add suitable quantity of water immersion decoction three times respectively after getting Rhizoma Paridis, Radix Ginseng, the Radix Astragali, the pulverizing of Caulis Spatholobi dry product respectively, filter, filtrate is stand-by, three filtrates is merged the back concentrate;
The preparation technology of described Radix Glycyrrhizae Preparata water extract is: get and add suitable quantity of water after the Radix Glycyrrhizae Preparata dry product is pulverized and soak and decoct three times, filter, filtrate is stand-by, will three filtrates merges the back and concentrates.
The present invention adopts advanced extractive technique, effective ingredient is extracted from Chinese herbal medicine, formulated according to certain ratio again, both guaranteed curative effect, can reduce toxic and side effects again, need take an osculum, so just save loaded down with trivial details that the patient makes up the prescription everyday, decocts medicinal herbs for each, the drawback of also having avoided once drinking a jorum Chinese medicine decoction and having influenced appetite has accomplished both to guarantee that stable effective dose has also made things convenient for taking of patient.For the patient of esophageal carcinoma one class, trace drinking-water is all very difficult usually because esophagus is blocked by the tumor body, let alone has drunk a jorum medicine, has so just successfully solved this difficult problem especially.Each patient only need be contained in an osculum medicinal liquid in the mouth, needn't be eager to swallow, and by slowly oozing down of medicinal liquid, slowly passes through focus, both can reach the effect of external application, also can play the effect of absorption for oral administration, is the effect of killing two birds with one stone.
One aspect of the present invention can be killed cancerous cell, removes lump, gets rid of pathological products such as expectorant, wet, the stasis of blood, poison, has reinforcing body resistance on the other hand, improves body constitution, and enhance immunity, resistance against diseases prolong life span, improve the effect of life quality.The present invention is through clinical observation, and effective percentage reaches 85%, and is fast to digestive system and respiratory system cancer patient produce effects especially, good effect.
The specific embodiment
Embodiment one:
Raw material weight ratio: disodium cantharidinate 2mg, scorpion venom 1mg, the plain 4g of Gekko Swinhonis, hirudin 40mg, organic selenium 17 μ g, Rhizoma Paridis water extract 9g, ginseng aqueous extract 6g, Rhizoma Atractylodis Macrocephalae water extract 15g, water extraction of astragalus membranaceus 20g, Caulis Spatholobi water extract 20g.
Preparation method:
The first step, preparation Gekko Swinhonis element: get Gekko Swinhonis dry product 500g and pulverize back adding dehydrated alcohol 500ml immersion 25 days, stir once every day, filters, filtrate is stand-by, filtering residue reuse 400ml soaked in absolute ethyl alcohol 25 days is filtered, and adds water 800ml recovery ethanol 80% after twice filtrate is merged and is concentrated into 500ml.
Second step, preparation organic selenium: get dried Folium Fici 1000g and pulverize, add 50～60 ℃ of water 1000ml dipping 6h, stir once per half an hour, filter, filtrate is stand-by, and filtering residue adds 50～60 ℃ of the same processing twice of water 800ml again, is concentrated into 500ml after three filtrates are merged.
The 3rd goes on foot, prepares respectively Rhizoma Paridis water extract, ginseng aqueous extract, Rhizoma Atractylodis Macrocephalae water extract, water extraction of astragalus membranaceus and Caulis Spatholobi water extract:
A, preparation Rhizoma Atractylodis Macrocephalae water extract: add water 700ml immersion 10h after getting Rhizoma Atractylodis Macrocephalae dry product 500g pulverizing, per hour stir once, filter, filtrate is stand-by, and filtering residue adds water 500ml and boils back slow fire and boiled 40 minutes, filter, filtrate is stand-by, and filtering residue adds water 500ml again and boils back slow fire and boiled 40 minutes, filters, filtrate is stand-by, and three filtrate merging are concentrated into 500ml.
B, preparation Rhizoma Paridis water extract, ginseng aqueous extract, water extraction of astragalus membranaceus and Caulis Spatholobi water extract: get Rhizoma Paridis, Radix Ginseng, the Radix Astragali, Caulis Spatholobi dry product 500g respectively, add water 500ml respectively and soak 2h, every half stirs once, boiling back slow fire then boiled 40 minutes, filter, filtrate is stand-by, filtering residue add respectively water 400ml boil the back slow fire boiled 40 minutes, filter, filtrate is stand-by, and filtering residue adds water 400ml respectively again and boils back slow fire and boiled 40 minutes, filters, filtrate is stand-by, is concentrated into 500ml after three filtrates are merged respectively.
The 4th step, take by weighing disodium cantharidinate, scorpion venom, Gekko Swinhonis element, hirudin, organic selenium, Rhizoma Paridis water extract, ginseng aqueous extract, Rhizoma Atractylodis Macrocephalae water extract, water extraction of astragalus membranaceus and Caulis Spatholobi water extract respectively and get final product by described weight ratio mix homogeneously.
Embodiment two:
Raw material weight ratio: disodium cantharidinate 4mg, scorpion venom 2mg, the plain 4g of Gekko Swinhonis, hirudin 50mg, organic selenium 50 μ g, Rhizoma Paridis water extract 10g, ginseng aqueous extract 6g, Rhizoma Atractylodis Macrocephalae water extract 15g, water extraction of astragalus membranaceus 40g, Caulis Spatholobi water extract 30g.
Preparation method: identical with embodiment one.
Embodiment three:
Raw material weight ratio: disodium cantharidinate 6mg, scorpion venom 3mg, the plain 6g of Gekko Swinhonis, hirudin 60mg, organic selenium 50 μ g, Rhizoma Paridis water extract 15g, ginseng aqueous extract 13g, Rhizoma Atractylodis Macrocephalae water extract 30g, water extraction of astragalus membranaceus 40g, Caulis Spatholobi water extract 30g, Radix Glycyrrhizae Preparata water extract 10g.
Preparation method: basic identical with embodiment one.Difference is:
Preparation Radix Glycyrrhizae Preparata water extract: add water 500ml immersion 2h after getting Radix Glycyrrhizae Preparata dry product 500g pulverizing, every half stirs once, boils back slow fire then and boils 40 minutes, filters, filtrate is stand-by, filtering residue adds water 400ml and boils back slow fire and boiled 40 minutes, filters, and filtrate is stand-by, filtering residue add again water 400ml boil the back slow fire boiled 40 minutes, filter, filtrate is stand-by, is concentrated into 500ml after three filtrates are merged.
Taking by weighing disodium cantharidinate, scorpion venom, Gekko Swinhonis element, hirudin, organic selenium, Rhizoma Paridis water extract, ginseng aqueous extract, Rhizoma Atractylodis Macrocephalae water extract, water extraction of astragalus membranaceus, Caulis Spatholobi water extract and Radix Glycyrrhizae Preparata water extract respectively gets final product by described weight ratio mix homogeneously.
Embodiment four:
Raw material weight ratio: disodium cantharidinate 4mg, scorpion venom 2mg, the plain 5g of Gekko Swinhonis, hirudin 50mg, organic selenium 30 μ g, Rhizoma Paridis water extract 12g, ginseng aqueous extract 10g, Rhizoma Atractylodis Macrocephalae water extract 20g, water extraction of astragalus membranaceus 30g, Caulis Spatholobi water extract 25g, Radix Glycyrrhizae Preparata water extract 8g.
Preparation method: identical with embodiment three.
Instructions of taking of the present invention: follow " " the principle of taking medicine continuously on time, quantitatively.
" on time " be meant 6,12,18,24 punctual medications in every day.Because the human biorhythm that self is arranged, in some particular moments of every day since the secretion of hypophysis cerebri change, thereby cause that people's absorption, the power of metabolic function change, and also influence division, growth, diffusion and the transfer of cancerous cell simultaneously.Catch these particular moment medications, messenger drug fully discharges the efficacy of a drug after entering human body, rapid activating immune system, thus improve therapeutic effect, play the effect of getting twice the result with half the effort.
" quantitatively " is because situations such as patient's age, body constitution, the state of an illness are different, so dosage is also answered individuation, makes it to bring into play maximum effect.The patient who just uses can begin to take from minimum dose 1.5ml, increase 0.1ml each time, that is to say one day increases 0.4ml, excessive responses such as back hour appearance half an hour to one is dizzy, nauseating until taking medicine, agitation, just the consumption of last time is deducted 0.1ml then takes next time, this amount is exactly this patient's a best dosage, takes no longer by this dose later on to change always.When reagent, occur dizzy, feel sick, excessive response such as agitation do not worry, because each to add dose very little, has only 0.1ml, blood drug level only can omit some height, just can recover normal by the body normal physiological metabolism in 2～4 hours.As take each 4ml and also do not occur above-mentioned reaction always, just do not need dosage again, take by each 4ml later on always.
" continuously " is because medicine can reach certain blood drug level after being absorbed into blood to one hour in half an hour, and this is that treatment is necessary, if not do not take continuously then the intravital blood drug level of patient will descend on time, do not reach due therapeutic effect.General one month is a course of treatment.
Clinical observation material: observe 1000 examples altogether, the 90%th, check is made a definite diagnosis through pathological section.Male's 503 examples wherein, women's 497 examples.The oldest person 75 years old, reckling 25 years old.Discovery was made a definite diagnosis the elder of the back course of disease 3 years, and is the shortest 1 month.Respiratory system 402 examples, digestive system 312 examples, female reproductive system tumor 113 examples, breast carcinoma 69 examples, lymphsystem 43 examples, thyroid tumor 26 examples, cerebroma 18 examples, skin carcinoma 11 examples, bladder cancer 6 examples.
Cure: account for 69%, refer to the clinical symptoms complete obiteration, auxiliary examinations such as B ultrasonic or CT are no abnormal.
Produce effects: account for 16%, refer to that cardinal symptom obviously alleviates.
Invalid: as to account for 15%, refer to that clinical symptoms does not have alleviate.
Case one: the king * *, man, 65 years old, Baoji, Shaanxi province people from county.Have a dull ache the several months in conscious right upper quadrant of the abdomen in 1998, find that through Baoji county hospital ultrasound diagnosis the liver right lower lobe has the irregular ultra dense echo shadow of 3.0 * 3.1 * 2.9cm,,, begin to take oral liquid in March, 1998 so doubt to hepatocarcinoma because of I have the hepatocarcinoma family history.Pain increased the weight of in 10 days, alleviate gradually after 15 days, one the course of treatment appetite recover, after take three courses of treatment continuously, no abnormal through Baoji county hospital ultrasound diagnosis.
Case two: Wu * *, man, 40 years old, Baoji, Shaanxi province people from county.Move in the Chinese People's Liberation Army the 3rd army hospital, the main suit January 16 calendar year 2001 because of obstructive jaundice, calcareous cholecystitis: sclera, xanthochromia March, it's 1 week toed for Satisfied.Check that through C T doubting is hepatocarcinoma, January 18, capable laparotomy exploration was found the abdomen diffusion entirely of hepatocholedchus cancer, did not have operation value, satisfied and sewed up, and January 23 left hospital.Begin to take oral liquid February, 1.8ml/ time, serve on four courses of treatment after self-induction condition of illness disappear.Do at Baoji county hospital July 11 calendar year 2001 and to do C T scanning in ultrasound diagnosis, on February 25th, 2002 and there is no unusual in the Chinese People's Liberation Army the 3rd army hospital.
Case three: horse * *, woman, 54 years old, Baoji, Shaanxi province people from city.Calendar year 2001 December 24 Nikkei Electricity in Shaanxi Province subcenter (409) the C T of hospital check that being diagnosed as nasopharyngeal carcinoma has invaded adjacent tissue, and lump C T value 31～61Hu does not wait.Readme pain unbearably, dysdipsia can't be had a meal.Begin to take oral liquid in March, 2002,10 days self-induction pain reliefs, can influent stream food, just can advance staple food a course of treatment, takes anosis pain feel after four courses of treatment continuously.JIUYUE is checked through the C T of Baoji central hospital and is shown no obvious abnormalities.
Case four: bundle * *, woman, 64 years old, people from Danyang City, Jiangsu Province.Be diagnosed as advanced lung cancer through Jiangsu Prov. Tumour Hospital the end of the year 1999, should not perform the operation, and can only go home to rest.Private prosecution whole body distending pain is spat blood unbearably, and dyspnea is had a dizzy spell, edema of the limbs, and the diet difficulty is advanced, and is overwhelmed with sorrow.On May 17th, 2000 began to take oral liquid, pain alleviated in 5 days, and spitting of blood reduces, but the influent stream food, swelling in 10 days begins to disappear, and life can be taken care of oneself after three courses of treatment, and begins to participate in some housework.
Case five: Wu * *, woman, 51 years old, the Yangzhou people of Jiangsu Province.Be diagnosed as stomach bottom cancer and involve cardia through the gastroscopy of Yangzhou the People's Hospital in October, 2000, and laparotomy ventrotomy is implemented to Hu Qiao hospital in the back, finds extensively to shift adhesion, can't excise, and closes abdomen then, leaves hospital after 10 days and go home to have a rest.The main suit: the feed singultus was had the hiccups 5 months, can only eat 1 month by influent stream, had a stomachache, vomits, can't take food for 1 week.On November 17th, 2004 began to take oral liquid, and nausea and vomiting stopped in 7 days, 10 days beginning influent stream foods, and the dizzy disappearance course of treatment, sleep is good, can advance staple food.Recovered normal after four courses of treatment.
Case six: discriminate * *, woman, 39 years old, people from Tianjin.Be diagnosed as rectal cancer through the blue or green hospital of willow, Tianjin Tumour Hospital's B ultrasonic, proctoscopy in 2003.Because of with family in straitened circumstances, financial insolvency great number medical fee, the recuperation of can only being in.Patient's private prosecution: constipation and anuresis, hemafecia, abdominal part is hard, and pain unbearably can't diet, and it is unusual to become thin.December begins to take oral liquid, 10 days pain reliefs, and hemafecia reduces, can the influent stream food.The molding of defecating a course of treatment, pain disappears, and can advance staple food.Partly recovery softness of two abdominal paries course of treatment, the people also begins to fill out.Five courses of treatment are after the ultrasound diagnosis of the blue or green hospital of willow is no abnormal.
Several problems that most of patient can run into are described at last: some normal reactions can occur after taking a period of time, what occur at present reaction the earliest is to take 4 days, evening probably by about 20 days.Below some common performances are enumerated out:
1. have a fever.Remove other fever factor as flu etc., the back body temperature of taking medicine can be increased to about 38 ℃, and at present the highest reaches 40.3 ℃.This is the immune system that medicine has fully activated human body, makes immunocyte do chemotactic motion, surrounds and engulfs foreign body such as tumor cell, produces a series of immunoreactive results.Discover that tumor cell belongs to cold property paraphyte, that is to say that the tumor cell ratio normal cell more fears high temperature.Because tumor is difficult to set up effective capillary network synchronously when breeding fast, it is poor to make it heat-sinking capability, responsive especially to heat.The intravital temperature of tumor can exceed 4～6 ℃ of normal structures during the body fever, and this can impel tumor cell a large amount of dead fast.
2. some increased the weight of before the pain ratio was taken medicine.This is to act on tumor cell after medicine enters human body, the reaction of struggle between vital QI and pathogen.When tumor cell is in the noenergy supply gradually, in the time of can't division growth, have just controlled the development of tumor, keenly feel and will descend when existing part tumor cell begins to reverse for normal cell until disappearance.
3. loose stool.If not the diarrhoea that improper diet produces, be exactly medicine impelling human body to remove refuse, get rid of stool, make to accumulate in intravital rubbish and get rid of external by stool.
4. urine color burn, perspiration are clamminess.This is the concrete manifestation that the human body metabolism is accelerated, and the interior refuse of body is excreted by urine, sweat gland.
5. skin pruritus.Be grown in body surface or near the tumor of body surface, as: skin carcinoma, lymphatic cancer, carcinoma of tongue etc., can see or feel the red and swollen pruritus of lump, this is the performance that the human immune system is activated, a large amount of eosinophilic granulocytes, neutrophilic granulocyte, lymphocyte, macrophage etc. around tumor, have been assembled, to the killing and wounding of tumor cell, make that lump reddens, heating by these immunocytes, sensation i.e. pain is itched again.
6. feel sick, vomit.The tumor patient of digestive system is most of this type of reaction may to occur, and the slowest available speed buccal is slowly swallowed, and can reach for oral administration and external application double effects.
Because the blood circulation in the skeleton with respect to its hetero-organization weakness, so it is later to occur the time ratio of normal reaction after the osteocarcinoma patient takes medicine, generally more than three months, this just requires the patient can not be too impatient, must adhere to taking.
The reaction that produces after different tumor patients is taken medicine also has nothing in common with each other, and one or more of above phenomenon may only occur, and this is individual difference, does not affect the treatment.There is not at present the back of taking medicine in accordance with regulations to produce the report of untoward reaction as yet.
Claims (6)
1. Chinese medicine oral liquid for the treatment of tumor, it is characterized in that described oral liquid made by the raw material of following weight ratio: disodium cantharidinate 2～6mg, scorpion venom 1～3mg, Gekko Swinhonis element 4～6g, hirudin 40～60mg, organic selenium 17～50 μ g, Rhizoma Paridis water extract 9～15g, ginseng aqueous extract 6～13g, Rhizoma Atractylodis Macrocephalae water extract 15～30g, water extraction of astragalus membranaceus 20～40g.
2. the Chinese medicine oral liquid of treatment tumor according to claim 1, it is characterized in that being added with in the described oral liquid raw material of following weight ratio: Radix Glycyrrhizae Preparata water extract is 6～10g.
3. the preparation method of the Chinese medicine oral liquid of a treatment tumor according to claim 1 is characterized in that:
A, preparation Gekko Swinhonis element: get the Gekko Swinhonis dry product and pulverize an amount of soaked in absolute ethyl alcohol twice of back adding, filter, twice filtrate is merged the back concentrate;
B, preparation organic selenium: get dried Folium Fici pulverizing back and add the suitable quantity of water dipping three times, filter, three filtrates merging backs are concentrated;
C, prepare Rhizoma Paridis water extract, ginseng aqueous extract, Rhizoma Atractylodis Macrocephalae water extract, water extraction of astragalus membranaceus and Caulis Spatholobi water extract respectively;
D, take by weighing disodium cantharidinate, scorpion venom, Gekko Swinhonis element, hirudin, organic selenium, Rhizoma Paridis water extract, ginseng aqueous extract, Rhizoma Atractylodis Macrocephalae water extract, water extraction of astragalus membranaceus and Caulis Spatholobi water extract respectively and get final product by described weight ratio mix homogeneously.
4. the preparation method of the Chinese medicine oral liquid of a treatment tumor according to claim 2 is characterized in that:
A, preparation Gekko Swinhonis element: get the Gekko Swinhonis dry product and pulverize an amount of soaked in absolute ethyl alcohol twice of back adding, filter, twice filtrate is merged the back concentrate;
B, preparation organic selenium: get dried Folium Fici pulverizing back and add the suitable quantity of water dipping three times, filter, three filtrates merging backs are concentrated;
C, prepare Rhizoma Paridis water extract, ginseng aqueous extract, Rhizoma Atractylodis Macrocephalae water extract, water extraction of astragalus membranaceus, Caulis Spatholobi water extract and Radix Glycyrrhizae Preparata water extract respectively;
D, weigh disodium cantharidinate, scorpion venom, Gekko Swinhonis element, hirudin, organic selenium, Rhizoma Paridis water extract, ginseng aqueous extract, Rhizoma Atractylodis Macrocephalae water extract, water extraction of astragalus membranaceus, Caulis Spatholobi water extract and Radix Glycyrrhizae Preparata water extract respectively and get final product by described weight ratio mix homogeneously.
5. according to the preparation method of the Chinese medicine oral liquid of claim 3 or 4 described treatment tumors, it is characterized in that:
The preparation technology of a, described Rhizoma Atractylodis Macrocephalae water extract: get and add suitable quantity of water after Rhizoma Atractylodis Macrocephalae dry product is pulverized and soak once, filter, filtrate is stand-by, and filtering residue adds suitable quantity of water again and decocts secondary filter, will three filtrates merges the back and concentrates;
The preparation technology of b, described Rhizoma Paridis water extract, ginseng aqueous extract, water extraction of astragalus membranaceus and Caulis Spatholobi water extract: add suitable quantity of water immersion decoction three times respectively after getting Rhizoma Paridis, Radix Ginseng, the Radix Astragali, the pulverizing of Caulis Spatholobi dry product respectively, filter, filtrate is stand-by, three filtrates is merged the back concentrate;
6. the preparation method of the Chinese medicine oral liquid of treatment tumor according to claim 4, the preparation technology who it is characterized in that described Radix Glycyrrhizae Preparata water extract is: add suitable quantity of water immersion decoction three times after getting the pulverizing of Radix Glycyrrhizae Preparata dry product, filter, filtrate is stand-by, three filtrates is merged the back concentrate.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109550042A (en) * | 2017-09-26 | 2019-04-02 | 深圳杏林春暖科技股份有限公司 | It is a kind of inhibit cancer composition and its application |
| CN112915106A (en) * | 2021-02-05 | 2021-06-08 | 张虎山 | Preparation and application of tumor immune microenvironment regulator |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1204522A (en) * | 1997-07-08 | 1999-01-13 | 孙贤华 | Chinese prescription medicine for treatment of digestive tract tumour and preparation method thereof |
| CN1698684A (en) * | 2004-05-19 | 2005-11-23 | 钟伟 | Anticancer tumour extinguishing toxin expelling decoction |
| CN1876159A (en) * | 2006-04-28 | 2006-12-13 | 钟龙 | Preparation method for preparing traditional Chinese medicine for treating tumour, and the prepared traditional Chinese medicine |
-
2010
- 2010-07-09 CN CN2010102228512A patent/CN101869700B/en not_active Expired - Fee Related
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1204522A (en) * | 1997-07-08 | 1999-01-13 | 孙贤华 | Chinese prescription medicine for treatment of digestive tract tumour and preparation method thereof |
| CN1698684A (en) * | 2004-05-19 | 2005-11-23 | 钟伟 | Anticancer tumour extinguishing toxin expelling decoction |
| CN1876159A (en) * | 2006-04-28 | 2006-12-13 | 钟龙 | Preparation method for preparing traditional Chinese medicine for treating tumour, and the prepared traditional Chinese medicine |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109550042A (en) * | 2017-09-26 | 2019-04-02 | 深圳杏林春暖科技股份有限公司 | It is a kind of inhibit cancer composition and its application |
| CN112915106A (en) * | 2021-02-05 | 2021-06-08 | 张虎山 | Preparation and application of tumor immune microenvironment regulator |
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| CN101869700B (en) | 2012-07-11 |
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