CN101785665A - Pulse diagnosis analyzer based on MEMS sensor - Google Patents

Pulse diagnosis analyzer based on MEMS sensor Download PDF

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Publication number
CN101785665A
CN101785665A CN 201010127112 CN201010127112A CN101785665A CN 101785665 A CN101785665 A CN 101785665A CN 201010127112 CN201010127112 CN 201010127112 CN 201010127112 A CN201010127112 A CN 201010127112A CN 101785665 A CN101785665 A CN 101785665A
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pulse
mems
microprocessor
diagnosis
module
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姚保寅
马志强
焦志超
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Beihang University
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Beihang University
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Abstract

The invention discloses a pulse diagnosis analyzer based on an MEMS sensor. A PVDF piezoelectric film force sensor adopting an MEMS is arranged on the radial artery of human body to be used as a sensing unit for acquiring pulse information; the collected pulse signals are digital signals, and waveform characteristic vector values of pulse waves are processed and analyzed by a single chip microcomputer (SCM) to obtain diagnosis results; and then, the diagnosis results are transmitted to a liquid crystal display (LCD) for displaying and a voice module for playing. The pulse diagnosis analyzer of the invention can also transmit pulse information to an upper computer through a wireless receiving and transmitting module and save and process data through pulse analysis software, thereby providing more detailed pulse diagnosis results for users or doctors. The pulse diagnosis analyzer of the invention can be carried conveniently, has low cost, is suitable for all classes of people to use, combines the modern science and technology and the pulse diagnosis theory, and develops and expands the Chinese traditional medicine.

Description

A kind of pulse diagnosis analyzer based on the MEMS pick off
Technical field
The present invention relates to a kind of pulse diagnostic apparatus, more particularly say, be meant a kind of pulse diagnostic apparatus based on MEMS (Micro-Electro-Mechanical Systems, MEMS) pick off.
Background technology
Chinese medicine has formed unique diagnosis system in its evolution, promptly hope, hear, ask, cut, and wherein most importantly be exactly to utilize feeling the pulse to come diagnose and treat diseases, and this also is an Ancient Chinese for one of elite of traditional medicine.But traditional since ancient times traditional Chinese medical science is the wearing or featuring stage armour arteries and veins always obtains pulse condition information, and can there be many subjective conjectures inevitably in this, and the sensation under the finger also is difficult to objective record, is unfavorable for traditional Chinese medical science development of modernization.
Summary of the invention
The objective of the invention is to propose a kind of pulse diagnosis analyzer based on the MEMS pick off, it includes MEMS pulse transducer, LCD MODULE, voice output module and microprocessor, the MEMS pulse transducer is connected by cable with microprocessor, the pulse condition information that microprocessor will be handled gained intuitively shows by LCD MODULE on the one hand, plays by the voice output module on the other hand; The MEMS pulse transducer places human body radial artery place, is used to gather the pulse condition information of human body.
Microprocessor is at first stored the pulse condition information that receives, then according to pulse condition identification diagnosis relation And
Figure GSA00000047065900012
Carrying out pulse waveform characteristic quantity K value extracts; The relevant information that the pulse waveform characteristic quantity K that extracts is characterized is exported to LCD MODULE, voice output module respectively at last.
The invention allows for another kind can networking, be suitable for the pulse diagnosis analyzer that medical institutions use, it includes MEMS pulse transducer, LCD MODULE, voice output module, microprocessor, wireless sending module, wireless receiving module and host computer, the MEMS pulse transducer is connected by cable with microprocessor, the pulse condition information that microprocessor will be handled gained intuitively shows by LCD MODULE on the one hand, play by the voice output module on the other hand, the third aspect transfers to pulse condition information in the host computer by radio receiving transmitting module; Host computer carries out the pulse wave wave amplitude of time domain relation and the analysis of pulsation time to pulse condition information, and parameters such as the ripple of output arteries and veins figure, the height in gorge, corresponding duration, the arteries and veins area of pictural surface, by analysis, can understand the frequency, the rhythm and pace of moving things, the power of arteries and veins power, the deficiency and excess and the pulse condition shape facility of arteries and veins gesture of pulsation to arteries and veins figure amplitude and duration; The MEMS pulse transducer places human body radial artery place, is used to gather the pulse condition information of human body.
The pulse diagnosis analyzer of the present invention's design has following advantage:
1. portable, adopt the PVDF pick off of two serial ports single-chip microcomputers of Mega162 and MEMS combined, make that whole analyser volume is little, in light weight, be easy to carry, be the caregiver of yours at one's side.
2. human oriented design is exported the mode that adopts video and voice for the pulse condition result, can make things convenient for the use of different crowd.Made things convenient for the pulsation situation of blind people know self as voice mode output pulse condition result.
3. the pulse condition diagnosis end in using by host computer, radio receiving transmitting module and terminal use carries out networking, has made things convenient for the different doctors of department of medical institutions to share this patient's pulsation data.In host computer according to the pulse wave spectrum theory, in conjunction with the pulse wave wave amplitude of Labview program development and the time domain relation of pulsation time, the pulse condition result who receives directly can be handled by this time-frequency relation, read parameters such as the ripple of arteries and veins figure, the height in gorge, corresponding duration, the arteries and veins area of pictural surface easily, by analysis, can understand the frequency, the rhythm and pace of moving things, the power of arteries and veins power, the deficiency and excess and the pulse condition shape facility of arteries and veins gesture of pulsation to arteries and veins figure amplitude and duration.
4. noinvasiveization, the PVDF pick off by MEMS contacts with the human body radial artery, relies on theory of Chinese medical science, gathers pulse condition information and diagnoses, to any side effect of personage.
Description of drawings
Fig. 1 is the external structure of pulse diagnosis analyzer of the present invention.
Fig. 2 is the functional block diagram that the present invention handles pulse condition information.
Fig. 3 is the functional block diagram that another kind of the present invention is handled pulse condition information.
Fig. 4 is the flow chart that carries out the identification diagnosis in the microprocessor of the present invention.
Fig. 5 is pulse wave wave amplitude and the surface chart such as time domain relation of pulsation time that shows in the host computer of the present invention.
Fig. 6 shows menu map in the host computer of the present invention.
Fig. 7 is the circuit theory diagrams of pulse diagnosis analyzer of the present invention.
The specific embodiment
The present invention is described in further detail below in conjunction with accompanying drawing.
Referring to Fig. 1, shown in Figure 2, a kind of pulse diagnosis analyzer of the present invention based on the MEMS pick off, it includes pulse transducer, LCD MODULE, voice output module and microprocessor, pulse transducer is connected by cable with microprocessor, the pulse condition information that microprocessor will be handled gained intuitively shows by LCD MODULE on the one hand, plays by the voice output module on the other hand; Microprocessor adopts the two serial ports single-chip microcomputers of Mega162, and identification diagnosis algorithm analysis programme is embedded in the two serial ports single-chip microcomputers of Mega162.
The two serial ports single-chip microcomputers of Mega162, the interface circuit of LCD MODULE, the interface circuit of voice output module are installed in the casing 1, the display screen of LCD MODULE is installed in loam cake 11 backs of casing 1, a plurality of buttons, speaker 13 etc. are installed on the upper face 12 of casing 1, perhaps on upper face 12, stick suggestive cautions such as operating instruction 14.Described button should be provided with return key 1A, multifunction key 1B, power switch key 1C etc. at least.Shown in Figure 1A, the center of multifunction key 1B is provided with " determining " button, is provided with " making progress ", " downwards ", " left " and " to the right " button around " determining ".
A kind of pulse diagnosis analyzer based on the MEMS pick off of the present invention is that the MEMS pulse transducer is placed the strength of human body radial artery, gathers the pulse condition information of human body.The signal that collects is a digital signal, send single-chip microcomputer to handle then, after the analysis of identification diagnosis algorithm the pulse condition diagnostic result is delivered to LCD and shows and voice output.
Referring to shown in Figure 3, the another kind of the present invention design is based on the pulse diagnosis analyzer of MEMS pick off, is the MEMS pulse transducer is placed the strength of human body radial artery, gathers the pulse condition information of human body.The signal that collects is a digital signal, send microprocessor (the two serial ports single-chip microcomputers of Mega162) to handle then, analyzes through the identification diagnosis algorithm, the pulse condition diagnostic result is delivered to LCD show and voice output.Single-chip microcomputer is also delivered to host computer (as computer, PC) with data by the FC-211/AG wireless data transmission module simultaneously, and host computer carries out pulse condition identification to the pulse condition diagnostic result that receives, and the pulse condition that identifies is carried out pathological analysis for expert, doctor.Computer is a kind ofly can carry out the modernized intelligent electronic device of massive values computation and various information processings automatically, at high speed according to prior program stored.Minimalist configuration is CPU 2GHz, internal memory 2GB, hard disk 180GB; Operating system is windows 2000/2003/XP.
Referring to shown in Figure 4, in the present invention, the identification diagnosis algorithm analytic process in the two serial ports single-chip microcomputers of Mega162 is: after the initialization, pulse transducer begins to gather pulse condition information, and this pulse condition information is exported to single-chip microcomputer;
The two serial ports single-chip microcomputers of Mega162 are at first stored the pulse condition information that receives, then according to pulse condition identification diagnosis relation
Figure GSA00000047065900031
And
Figure GSA00000047065900032
Carrying out pulse waveform characteristic quantity K value extracts.P dThe expression diastolic pressure, P sThe expression systolic pressure, T represents pulse cycle, t represents to gather constantly, the pulse pressure value of inscribing when P (t) expression is gathered, dt is a differential unit.
The medical expert is by the Clinical detection of zoopery and healthy people of thousands of routine all ages and classes and cardiovascular patient, the verified respective change that will cause pulse waveform feature and area by the variation on cardiovascular physiology and the pathology, it can be reflected in the variation of characteristic quantity K value, not only very regular, and quite responsive, be an important physical signs of cardiovascular clinical examination.In the present invention, by digital information characteristic feature amount K value, K=0.25~0.33 scope belongs to then that blood vessel elasticity is good, resistance of blood flow is little.The voice output module then can be play corresponding voice, as " pulse condition is good ", " noting health care " etc.
In the present invention, pulse transducer adopts the PVDF (piezoelectric membrane) of MEMS, piezoelectric film material (PVDF) has good time and temperature stability and very high intensity and very wide frequency response, and the acoustic impedance of PVDF and human body and human body soft tissue coupling is good, has guaranteed the pulse signal collection accurately and reliably.This pick off adopts the 5V power supply, numeral output.During use the MEMS pulse transducer placed the strength of human body radial artery, tighten wrist strap, arm is put on the platform, flushes with heart, and mood is loosened, and breathes steadily, begins to gather the pulse condition information of human body.
In the present invention, microprocessor (referring to shown in Figure 7) need be considered following functional module: the USART double serial port communication, and liquid crystal communication, the IO interface circuit, and power reguirements etc.In the microprocessor of AVR series, Mega162 is 8 AVR microprocessors of a high-performance, low-power consumption, has advanced risc architecture, non-volatile program and data storage, two line interfaces of byte-oriented, two programmable serial USART, and also structure is comparatively simple.So in this programme, selected use Mega162 as microprocessor.The AVR kernel has abundant instruction set and 32 general purpose working registers.All depositors all directly are connected with arithmetic logic unit (ALU), and this structure has improved code efficiency greatly.
Microprocessor is connected as Fig. 7 with the circuit of voice output, video, wireless receiving and dispatching:
10 ends of Mega162 chip, 11 ends are connected with 11 ends, 12 ends of MAX232 chip respectively; 14 ends of MAX232 chip, 13 ends are connected with 4 ends, 3 ends of MEMS pulse transducer;
15 ends of Mega162 chip, 16 ends, 24 ends, 17 ends, 1 end are connected with 4 ends~9 ends of PM_50100 chip respectively;
4 ends of Mega162 chip are connected with 4 ends of FC211/AG chip;
39 ends of Mega162 chip~32 ends, 23 ends, 22 ends, 21 ends are connected with 14 ends~7 ends, 4 ends, 5 ends, 6 ends of 1602C chip respectively.
In the present invention, the voice output module is chosen PM_50 series (PM_50100 chip) intelligent sound chip, and it is a voice playing circuit, also is intelligent single-chip microcomputer.Its tonequality level, price all are better than famous ISD circuit, and indexs such as development and Design is simply spent, the simple degree of Based Intelligent Control, overall price/performance ratio will far surpass ISD.
This chip is made of the voice single-chip microcomputer and the set of FLASHRAM memorizer of special use, and several seconds to 100 seconds multistage voice play function is arranged, and the programmable intelligent characteristic of single-chip microcomputer is also arranged.Its main feature has:
(1) easy to use.
(2) FLASHRAM structure can erasable repeatedly typing, and the life-span is more than 10,000 times.
(3) directly drive 8 ohm 0.5 watt loudspeaker.
(4) a series of many specifications can be called, and development system is shared.
In the present invention, what the LCD display module was selected for use is 1602C ocra font ocr type LCD MODULE, is mainly used to display pulse characteristic quantity K value (K=0.25~0.33 scope belongs to then that blood vessel elasticity is good, resistance of blood flow little).
In the present invention, radio receiving transmitting module is used for realizing information interaction with host computer.Adopt FC211/AG micropower wireless data transmission module.The FC211/AG chip is the embedded micropower wireless data transmission module of multi-channel high-speed rate of new generation, numerous channels can be set, transmitting power 20mW.Can use in the embedding equipment, Products Compatibility is strong, and the user is easy to use.In this product, baud rate is made as 9600bps.
Adopted the Labview program development in host computer pulse condition discriminatory analysis program, its interface such as Fig. 5, shown in Figure 6.In the present invention, mainly be that (to be that Modern Physics is a kind of commonly used do methods of numerical to cyclic fluctuation information to frequency-domain analysis method for the time domain relation of analyzing pulse wave wave amplitude and pulsation time.It is by discrete Fourier transform, and the pulse wave curves of time domain is transformed to frequency domain, and a pulse wave complexity, periodically variable is resolved into the harmonic wave of different frequency, extracts and the corresponding information of physiological pathology of human body from the pulse wave spectrum.), the pulse condition result who receives directly can be handled by this time-frequency relation, read parameters such as the ripple of arteries and veins figure, the height in gorge, corresponding duration, the arteries and veins area of pictural surface easily, by analysis, can understand the frequency, the rhythm and pace of moving things, the power of arteries and veins power, the deficiency and excess and the pulse condition shape facility of arteries and veins gesture of pulsation to arteries and veins figure amplitude and duration.Some have the characteristic point of points of obvious physiological significance as the evaluation pulse wave in the arteries and veins figure curve by extracting in time-domain analysis, and are directly perceived, are more easily accepted by the clinicist.User can carry out step by step operation according to the interface as Fig. 5 and Fig. 6 that provides and realize analysis to sensor acquisition information.
A kind of pulse diagnosis analyzer of the present invention based on the MEMS pick off, the user opens the instrument start button, shows the start interface, and " health is from here on! " select mode of operation (this locality or wireless transmission) then, and category of language (Chinese is still English), follow typing user profile, (name, sex, age etc.) use so that access historical catalogue later on.Point " determines " that button can begin to detect, and relay indicating light is bright, instrument is not placed on the strength of scratching tremulous pulse as the user, then provides alarm and alarm lamp is bright.After measuring certain hour, point " stops ", and data and curve are preserved automatically.Deposit historical catalogue in.Main functional test is heart rate and pulse condition.The oscillogram of test is shown in 5.

Claims (6)

1. pulse diagnosis analyzer based on the MEMS pick off, it is characterized in that including MEMS pulse transducer, LCD MODULE, voice output module and microprocessor, the MEMS pulse transducer is connected by cable with microprocessor, the pulse condition information that microprocessor will be handled gained intuitively shows by LCD MODULE on the one hand, plays by the voice output module on the other hand; The MEMS pulse transducer places human body radial artery place, is used to gather the pulse condition information of human body.
2. the pulse diagnosis analyzer based on the MEMS pick off according to claim 1 is characterized in that: also include wireless sending module, wireless receiving module and host computer; Wireless sending module and wireless receiving module are used for realizing that pulse condition result transmission with microprocessor processes is to host computer; Wireless sending module is connected with microprocessor, and wireless receiving module is connected with host computer.
3. the pulse diagnosis analyzer based on the MEMS pick off according to claim 1 and 2 is characterized in that: described microprocessor adopts the two serial ports single-chip microcomputers of Mega162, and the pulse analysis handling procedure is embedded in the two serial ports single-chip microcomputers of Mega162.
4. the pulse diagnosis analyzer based on the MEMS pick off according to claim 1 and 2 is characterized in that: microprocessor is at first stored the pulse condition information that receives, then according to pulse condition identification diagnosis relation
Figure FSA00000047065800011
And
Figure FSA00000047065800012
Carrying out pulse waveform characteristic quantity K value extracts; The relevant information that the pulse waveform characteristic quantity K that extracts is characterized is exported to LCD MODULE, voice output module respectively at last; P dThe expression diastolic pressure, P sThe expression systolic pressure, T represents pulse cycle, t represents to gather constantly, the pulse pressure value of inscribing when P (t) expression is gathered, dt is a differential unit.
5. the pulse diagnosis analyzer based on the MEMS pick off according to claim 1 and 2 is characterized in that: described pulse transducer adopts the PVDF pick off of MEMS.
6. the pulse diagnosis analyzer based on the MEMS pick off according to claim 2, it is characterized in that: the pulse condition discriminatory analysis program that adopted the Labview program development in the host computer, be to be used for analyzing pulse wave wave amplitude and the time domain of pulsation time relation, the pulse condition result who receives directly can be handled by this time-frequency relation, read parameters such as the ripple of arteries and veins figure, the height in gorge, corresponding duration, the arteries and veins area of pictural surface easily, by analysis, can understand the frequency, the rhythm and pace of moving things, the power of arteries and veins power, the deficiency and excess and the pulse condition shape facility of arteries and veins gesture of pulsation to arteries and veins figure amplitude and duration.
CN 201010127112 2010-03-18 2010-03-18 Pulse diagnosis analyzer based on MEMS sensor Pending CN101785665A (en)

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Cited By (10)

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CN102334981A (en) * 2011-07-23 2012-02-01 浙江大学 Multiplex human pulse wave signal acquisition system
CN102670219A (en) * 2012-05-25 2012-09-19 浙江大学 System for acquiring and restoring somatosensory pressure signal
CN102669848A (en) * 2012-05-16 2012-09-19 苏州纳华美纳米科技有限公司 Monitoring system for human body physiological index and clothes microclimate index
CN102715917A (en) * 2012-02-22 2012-10-10 Tcl集团股份有限公司 Fetus-voice meter for remote monitoring
CN103251390A (en) * 2013-05-13 2013-08-21 曾建新 Baby cold-hot radio frequency wireless intelligent monitoring system
CN104055495A (en) * 2014-07-07 2014-09-24 北京印刷学院 Pulse condition judging method and device based on time-frequency tracking
CN105877720A (en) * 2016-06-24 2016-08-24 郭润峰 Human pulse and body temperature monitoring device
CN106618514A (en) * 2016-12-29 2017-05-10 厦门大学嘉庚学院 Labview-based wireless animal rectal temperature acquisition system and method
CN107334464A (en) * 2016-12-05 2017-11-10 深圳大学 A kind of pulse meter based on the embedded nano thin-film photoelectric sensor of graphene edge
CN109431476A (en) * 2018-12-17 2019-03-08 内蒙古民族大学 A kind of Mongolian medicine's pulse-tracing collection analysis system

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Cited By (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102334981A (en) * 2011-07-23 2012-02-01 浙江大学 Multiplex human pulse wave signal acquisition system
CN102715917A (en) * 2012-02-22 2012-10-10 Tcl集团股份有限公司 Fetus-voice meter for remote monitoring
CN102669848A (en) * 2012-05-16 2012-09-19 苏州纳华美纳米科技有限公司 Monitoring system for human body physiological index and clothes microclimate index
CN102670219A (en) * 2012-05-25 2012-09-19 浙江大学 System for acquiring and restoring somatosensory pressure signal
CN103251390A (en) * 2013-05-13 2013-08-21 曾建新 Baby cold-hot radio frequency wireless intelligent monitoring system
CN103251390B (en) * 2013-05-13 2015-06-24 曾建新 Baby cold-hot radio frequency wireless intelligent monitoring system
CN104055495A (en) * 2014-07-07 2014-09-24 北京印刷学院 Pulse condition judging method and device based on time-frequency tracking
CN105877720A (en) * 2016-06-24 2016-08-24 郭润峰 Human pulse and body temperature monitoring device
CN107334464A (en) * 2016-12-05 2017-11-10 深圳大学 A kind of pulse meter based on the embedded nano thin-film photoelectric sensor of graphene edge
CN107334464B (en) * 2016-12-05 2020-05-19 深圳大学 Sphygmometer based on graphene edge embedded nano-film photoelectric sensor
CN106618514A (en) * 2016-12-29 2017-05-10 厦门大学嘉庚学院 Labview-based wireless animal rectal temperature acquisition system and method
CN109431476A (en) * 2018-12-17 2019-03-08 内蒙古民族大学 A kind of Mongolian medicine's pulse-tracing collection analysis system

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