CN101779947B - Confocal microscope and rigid electronic arthroscope integrated system - Google Patents
Confocal microscope and rigid electronic arthroscope integrated system Download PDFInfo
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- CN101779947B CN101779947B CN2010101162861A CN201010116286A CN101779947B CN 101779947 B CN101779947 B CN 101779947B CN 2010101162861 A CN2010101162861 A CN 2010101162861A CN 201010116286 A CN201010116286 A CN 201010116286A CN 101779947 B CN101779947 B CN 101779947B
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Abstract
The invention belongs to the field of medical appliances and in particular discloses a confocal microscope and rigid electronic arthroscope integrated system. The system comprises a rigid electronic arthroscope, a camera mainframe, a light source mainframe and related monitors, wherein the rigid electronic arthroscope is at least provided with a straight appliance channel; a rigid endoscope end is provided with a confocal microscope, confocal laser heads, a lens of an endoscopic electro optical system, a lightguide fiber and an appliance channel exit; and the rigid electronic arthroscope is designed into the integrated confocal microscope rigid electronic arthroscope. The system introduces the advanced confocal laser scanning microscopy into the diagnosis in orthopaedic surgery and integrates the confocal microscope and an electron optical system. When the endoscope enters into the wounded parts, through interaction between the blue laser beams of 488nm sent by the confocal micro laser heads at the endoscope end and the fluorescein sodium, the doctors can monitor the micro pathological changes of the wounded parts via the confocal microscope monitors and carry out real-time biopsy and treatment. The system can solve the problem caused by biopsy, introduce diagnosis and the knowledge of the joints to a microworld and provide a powerful diagnostic tool for diagnosing and knowing the joints.
Description
Technical field
The invention belongs to field of medical appliances, be specifically related to a kind of core medical instrument that modern medicine is carried out bone surgery.
Prior art
Carry out bone surgery at present, use be special-purpose orthopaedics arthroscope, the damage and the pathological changes that are used to observe the affected part.In general, arthroscope uses traditional lens pillar optical system, and arthroscope does not possess instrument channel, can not feed the operation that operating theater instruments is carried out orthopaedics, and uses the arthroscope of traditional lens pillar optical system, and the quality of image is subjected to certain restriction.When the doctor need determine the character of the pathological changes in patient affected part or pathological changes, need usually to take out linked groups, in laboratory, chemically examine, and be difficult to accurately determine biopsy site when getting biopsy, be unfavorable for clinical timely diagnosis and treatment.Also there is not at present a kind of technology of under the situation of biological tissue, its character being diagnosed in the world,
In the prior art, the burnt microtechnique of copolymerization is as a kind of brand-new imaging technique, the Laser Scanning Confocal Microscope technology is used widely in biological study, its application expands in the research work of subjects such as cytology, microbiology, developmental biology, hereditism, neurobiology, physiology and pathology at present, becomes the important tool of modern biology microexamination.Therefore, how the burnt micro-imaging technique of copolymerization, micro laser technology are used in combination with the orthopaedics arthroscope, being implemented under the situation of biological tissue accurate positioning and qualitative, that orthopedics patient is carried out detailed inspection is particularly urgent.
Summary of the invention
In order to overcome above-mentioned the deficiencies in the prior art, the objective of the invention is to burnt microtechnique of copolymerization and hard electronic arthroscope are organically combined, a kind of confocal microscope and rigid electronic arthroscope integrated system is proposed, this confocal microscope and rigid electronic arthroscope integrated system can make the operator accurately determine biopsy site, observe the macroscopical situation and the microcosmic situation in joint simultaneously, in current operation and inspection, suspicious lesions is carried out instant analysis and detection, overcome the drawback that biopsy at random brings, help to improve clinical therapeutic effect and reduce medical treatment cost.
For realizing above-mentioned technical purpose, the present invention is achieved through the following technical solutions:
Confocal microscope and rigid electronic arthroscope integrated system of the present invention, the endoscopic cold light source main frame that comprises the hard electronic arthroscope and be attached thereto, hard electronic arthroscope main frame, described hard electronic arthroscope comprises the hard scope end that hard material is made, the cold light source interface, the view data output interface, instrument channel, described hard arthroscope is provided with straight line type instrument channel at least, described hard scope end is provided with the Laser Scanning Confocal Microscope head, the confocal laser head, the camera lens of scope electron-optical system, light-conductive optic fibre and instrument channel outlet, first of Laser Scanning Confocal Microscope head and confocal laser are integrated into hard scope end, are designed to the hard electronic arthroscope confocal microscope and rigid electronic arthroscope integrated.
The diameter of described hard scope end is smaller or equal to 8.0mm, and its length is 150mm～200mm.
In addition, for certainty and the stability that improves operative process, the axis of described view data output interface and scope is at 45.
Described confocal microscope and rigid electronic arthroscope integrated shank design has control unit, make things convenient for the doctor to carry out the burnt micro-control of copolymerization, control unit includes the burnt micro-unlatching switch of copolymerization, freeze frame switch, amplifies minification by-pass cock etc., and control unit adopts high temperature resistant and the waterproof material design.
In the present invention, described hard electronic arthroscope uses CCD electron-optical chip, and its chip adopts≤1/4 ", the CCD of at least 48 universal effect pixels, the angle of view is more than 100 °, and CCD is installed in the front end place of hard electronic arthroscope hard scope end.
As the further improvement of above-mentioned technology, described confocal microscope and rigid electronic arthroscope integrated main frame is circumscribed with two medical monitors, shows the burnt micro-image of endoscopic image and copolymerization respectively; Also comprise with the confocal micro hard electronic arthroscope main frame and be connected the keyboard of being convenient to operate.
Compared with prior art, the invention has the beneficial effects as follows:
Confocal microscope and rigid electronic arthroscope integrated system of the present invention is on the Arthroscopic basis of hard electronic, introduces the burnt microtechnique of advanced copolymerization and Laser Scanning Confocal Microscope head and laser head are integrated in the hard electronic arthroscope.At the wavelength that the burnt micro laser hair of the copolymerization of scope goes out is under the combined effect of the blue laser of 488nm and fluorescein sodium, the doctor presses close to the affected part, joint by operating integrated confocal microscopy hard gallbladder mirror, can be intracellular dynamically with 30 frame/seconds (fps) or above speed record, the burnt micro-main frame of copolymerization can be with 230fps or above speed photographic images, pass through confocal microscope and rigid electronic arthroscope integrated system, carrying out live body detects, immediately joint tissue or pathological changes etc. is diagnosed and treated, the doctor can observe the macroscopical situation and the microcosmic situation in affected part, joint simultaneously, provides new platform for the doctor carries out real-time cell biopsy.
Description of drawings
Fig. 1 is a confocal microscope and rigid electronic arthroscope integrated system sketch map of the present invention.
Fig. 2 is a confocal microscope and rigid electronic arthroscope integrated structural representation of the present invention.
Fig. 3 is a confocal microscope and rigid electronic arthroscope integrated end construction sketch map of the present invention.
Fig. 4 is that sketch map is used in confocal microscope and rigid electronic arthroscope integrated system operation of the present invention.
The specific embodiment
The present invention is described in further detail below in conjunction with accompanying drawing:
As shown in Figure 1, that confocal microscope and rigid electronic arthroscope integrated system of the present invention comprises is confocal microscope and rigid electronic arthroscope integrated 1, light source main frame 2, confocal micro hard electronic arthroscope main frame 3, keyboard 4, two medical monitors 5 and 6, shows the image of hard electronic joint camera lens and Laser Scanning Confocal Microscope head respectively.
Be illustrated in figure 2 as the structural representation of confocal microscope and rigid electronic arthroscope integrated 1 among the present invention, described confocal microscope and rigid electronic arthroscope integrated 1 comprises hard scope end 11, cold light source interface 12, view data output interface 13, the instrument channel 14 that hard material is made, control unit 15.View data output interface 13 is connected with confocal micro hard electronic arthroscope main frame 3 by data wire, to confocal micro hard electronic arthroscope main frame 3 transmission endoscopic optical system images and the burnt micro-image of copolymerization.Instrument channel 14 is the linear type instrument channel, and the diameter of instrument channel 14 is smaller or equal to 3.0mm; Hard electronic arthroscope 1 optical system adopts the higher electronic CCD chip optical system of resolution, its chip adopts≤1/4 "; the CCD of at least 48 universal effect pixels, the angle of view is more than 100 °, and CCD is installed in the front end place of hard electronic arthroscope 1 work end.Control unit 15 makes things convenient for the doctor to carry out the burnt micro-control of copolymerization, and control unit 15 includes the burnt micro-unlatching switch of copolymerization, and the freeze frame switch amplifies minification by-pass cock etc., and control unit adopts high temperature resistant and the waterproof material design.
Fig. 3 is the end construction sketch map of hard electronic arthroscope 1 among the present invention.The hard scope end 11 of hard electronic arthroscope 1, its diameter are smaller or equal to 8.0mm, and length is 150mm～200mm.Hard scope end 11 is integrated Laser Scanning Confocal Microscope head 131, the burnt micro laser head 132 of copolymerization, the camera lens 133 of scope electron-optical system, light-conductive optic fibre 121 and instrument channel outlet 141.
As Fig. 4, in conjunction with shown in Figure 1, the operation sketch map of confocal microscope and rigid electronic arthroscope integrated system of the present invention, the doctor does a miniature incision in affected part, patient joint 7, then hard electronic arthroscope 1 is inserted, can observe the pathological changes in affected part, patient joint 7 by monitor 5, detect the tissue property in affected part, joint 7, the burnt micro laser head 132 of copolymerization that can control hard electronic arthroscope 1 by operation control unit 15 sends the blue laser that frequency is 488nm, blue laser acts on mutually with the fluorescein sodium in affected part, patient joint 7, can obtain the burnt micro-image of copolymerization clearly, from display 6 outputs, the doctor can carry out live body and detect under the help of hard electronic arthroscope 1, immediately joint tissue or pathological changes etc. is diagnosed and treated.
Claims (5)
1. confocal microscope and rigid electronic arthroscope integrated system, the endoscopic cold light source main frame that comprises the hard electronic arthroscope and be attached thereto, hard electronic arthroscope main frame, keyboard and the monitor that matches; Described hard electronic arthroscope comprises hard scope end, cold light source interface, view data output interface, instrument channel, described hard arthroscope is provided with straight line type instrument channel at least, it is characterized in that: described hard scope end is provided with the camera lens of Laser Scanning Confocal Microscope head, confocal laser head, scope electron-optical system, light-conductive optic fibre and instrument channel outlet, first of Laser Scanning Confocal Microscope head and confocal laser are integrated into hard scope end, are designed to the hard electronic arthroscope confocal microscope and rigid electronic arthroscope integrated.
2. confocal micro hard electronic arthroscope system according to claim 1 is characterized in that: the diameter of described hard scope end is smaller or equal to 8.0mm, and its length is 150mm～200mm.
3. the burnt hard electronic arthroscope system of integrated copolymerization according to claim 1, it is characterized in that: the axis of described view data output interface and scope is at 45.
4. according to each described confocal microscope and rigid electronic arthroscope integrated system of claim 1 to 3, it is characterized in that: described hard electronic arthroscope uses CCD electron-optical chip, its chip adopts≤1/4 "; the CCD of at least 48 universal effect pixels; the angle of view is more than 100 °, and CCD is installed in the front end place of hard electronic arthroscope hard scope end.
5. according to each described confocal microscope and rigid electronic arthroscope integrated system of claim 1 to 3, it is characterized in that: described confocal microscope and rigid electronic arthroscope integrated shank design has the control unit that makes things convenient for the doctor to carry out the burnt micro-control of copolymerization, this control unit includes the burnt micro-unlatching switch of copolymerization, freeze frame switch and amplifies the minification by-pass cock, and control unit adopts high temperature resistant and the waterproof material design.
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2010101162861A CN101779947B (en) | 2010-02-12 | 2010-02-12 | Confocal microscope and rigid electronic arthroscope integrated system |
| PCT/CN2010/075583 WO2011097870A1 (en) | 2010-02-12 | 2010-07-30 | Integrated confocal microscopic hard endoscope system |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2010101162861A CN101779947B (en) | 2010-02-12 | 2010-02-12 | Confocal microscope and rigid electronic arthroscope integrated system |
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| Publication Number | Publication Date |
|---|---|
| CN101779947A CN101779947A (en) | 2010-07-21 |
| CN101779947B true CN101779947B (en) | 2011-09-14 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN2010101162861A Expired - Fee Related CN101779947B (en) | 2010-02-12 | 2010-02-12 | Confocal microscope and rigid electronic arthroscope integrated system |
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Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2011097870A1 (en) * | 2010-02-12 | 2011-08-18 | 广州市番禺区胆囊病研究所 | Integrated confocal microscopic hard endoscope system |
| RU2639037C2 (en) * | 2012-06-26 | 2017-12-19 | Конинклейке Филипс Н.В. | Biopsy needle with large interfiber distance at tip |
| WO2015029040A1 (en) | 2013-08-31 | 2015-03-05 | Morena Medical Applications Ltd. | Endoscope with shared working channel |
| CN106204609B (en) * | 2016-07-20 | 2019-03-19 | 复旦大学附属中山医院 | The processing of Laser scanning confocal microscope lung image and analysis system and method |
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Effective date of registration: 20180720 Address after: 511400 the Tianan scientific and technological innovation building in Panyu Energy Conservation Science Park, No. 555 Panyu District Panyu Avenue, Guangzhou City, Guangdong Province, 401, 402, 403, 404, 405, 406, 407, 408, 409, 410, 411, 411, 412, Patentee after: Guangzhou Baodan Medical Apparatus Co., Ltd. Address before: 511470 Xingye Road, Dagang Town, Panyu District, Guangzhou City, Guangdong Province Patentee before: Guangzhou Fanyu Gallbladder Disease Research Institute |
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