CN101766749A - Chinese patent medicine for treating chronic rhinitis and nasosinusitis - Google Patents
Chinese patent medicine for treating chronic rhinitis and nasosinusitis Download PDFInfo
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- CN101766749A CN101766749A CN 200810240981 CN200810240981A CN101766749A CN 101766749 A CN101766749 A CN 101766749A CN 200810240981 CN200810240981 CN 200810240981 CN 200810240981 A CN200810240981 A CN 200810240981A CN 101766749 A CN101766749 A CN 101766749A
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Abstract
The invention discloses a Chinese patent medicine for treating chronic rhinitis and nasosinusitis, belonging to the Chinese medicine pharmaceutical field. The medicine is prepared into a tablet by the active pharmaceutical ingredients of radix codonopsis, largehead atractylodes rhizome, radix angelicae dahuricae, asarum, cape jasmine fruit, flos magnoliae, loquat leaf, balloonflower root, pericarpium granati and rhizoma smilacis glabrae according to the conventional process. The medicine has the functions of clearing away heat and toxic materials, strengthening body resistance and eliminating evil, and clearing the nasal passage, and can be used for treating the chronic rhinitis and the nasosinusitis patients with the symptoms of nasal obstruction, rhinocnesmus, dense nasal discharge, persistent rhinostegnosis, baryodmia due to wind-heat invading lung and accumulation of damp-heat in the body.
Description
Technical field
The invention belongs to field of traditional Chinese medicine pharmacy, be specifically related to a kind of Chinese patent medicine for the treatment of chronic rhinitis, sinusitis.
Background technology
Chronic rhinitis, sinusitis are commonly encountered diseases, and frequently-occurring disease is because internal organs the bottom of heart, spleen, stomach, the heart, liver, the imbalance of kidney yin sun, and be damp and hot, wind-fire is superfluous, rises in throat, or its table that overflows, and it is obstructed to form QI and blood, coalescent in bulk and redness.Such disease patient's nasal mucosa deep artery is chronic expansion state, lose contractile function, the concha nasalis inferior spongy tissue also is chronic expansion, it is main inflammatory infiltration that lymphocyte and plasma cell are arranged around blood vessel and the body of gland, the mucous glands function is active, secretions increase, proper mucous membrane edema, in inflammatory process, infect for seeing with the purulence coccus more.Treat untimely or thoroughly easily do not cause the state of an illness to increase the weight of, can cause hyposmia when serious, amnesia, symptoms such as headache, influence study is then worked.
Chronic rhinitis, sinusitis belong to motherland's medical science " stuffy nose, " nasal sinusitis " category.Its pathogenesis polyphyly wind heat is attacked on lung or the gallbladder-heat and is violated, and pathogenic heat are stifling, and bright Tianjin is that expectorant is tears, and key is unfavorable clearly, so that it is obstructed to have a stuffy nose, and the sticking turbid Huang of watery nasal discharge is thick, and baryo,dmia is often done giddy, headache, for a long time difficult healing.Main Therapeutic Method to such disease has block therapy, the little liquid medicine injection of concha nasalis inferior mucosa, nasal drop, laser cryotherapy and inferior turbinectomy etc. at present.The rhinitis medicine that wherein Drug therapy adopted roughly has, BIYANKANG tablet, HUODAN WAN pill, Nasivin, BIGENZHI spray water, nasal drop nasal drop etc.Above-mentioned existing various medicines, all effective in cure to rhinitis to a certain extent, but all not very good, treatment mostly is symptomatic treatment.Antibacterials commonly used or antibiosis be infection usually, but prolonged application then develops immunity to drugs, and also selects some topical therapeutic medicines for use, and as relief of symptoms such as ephedrine and BIYANJING, but long-term extensive application can make nasal mucosa knock-on property congested and produce medicamentous rhinitis.
Summary of the invention
The objective of the invention is to overcome the deficiency of existing medicine, select, make things convenient for patient treatment, and a kind of Chinese patent medicine for the treatment of chronic rhinitis, sinusitis is provided, comprise its preparation technology for extensive patients provides new medication.
The present invention is achieved by the following technical solutions:
A kind of Chinese patent medicine for the treatment of chronic rhinitis, sinusitis, it is that raw material is made by following parts by weight of Chinese traditional medicine material:
Radix Codonopsis 10～50 weight portion Rhizoma Atractylodis Macrocephalaes 20～70 weight portion Radixs Angelicae Dahuricae 20～60 weight portions
Herba Asari 15～60 weight portion Fructus Gardeniaes 30～90 weight portion Flos Magnoliaes 40～120 weight portions
Folium Eriobotryae 30～90 weight portion Radix Platycodoniss 40～90 weight portion Pericarpium Granatis 10～50 weight portions
Rhizoma Smilacis Glabrae 40～120 weight portions
And the weight portion proportioning of described each Chinese crude drug raw material is:
The Radix Codonopsis 30 weight portion Rhizoma Atractylodis Macrocephalaes 50 weight portion Radixs Angelicae Dahuricae 40 weight portions
Herba Asari 45 weight portion Fructus Gardeniaes 60 weight portion Flos Magnoliaes 80 weight portions
Folium Eriobotryae 60 weight portion Radix Platycodoniss 70 weight portion Pericarpium Granatis 30 weight portions
Rhizoma Smilacis Glabrae 90 weight portions
Its preparation technology may further comprise the steps:
Step 1: get Radix Codonopsis, the Rhizoma Atractylodis Macrocephalae, the Radix Angelicae Dahuricae, Herba Asari, mix, add alcohol reflux, filter (medicinal residues are standby), decompression filtrate recycling ethanol is to extractum, and drying is pulverized, and sieves, and gets the ethanol extract fine powder, and is standby;
Step 2: Six-elements such as above-mentioned alcohol extraction medicinal residues and all the other Fructus Gardeniaes are mixed, decoct with water, filter, filtrate is concentrated into the thick paste that relative density is 1.22～1.26 (70 ℃), and drying is pulverized, sieve, the water extract fine powder, standby;
Step 3: the ethanol extract fine powder and the water extracting alcohol hypostasis fine powder that make is mixed, add suitable proper quantity of medicinal auxiliary material, mixing is granulated, and suppresses in flakes, promptly.
Its function cures mainly and is: heat-clearing and toxic substances removing, strengthening vital QI to eliminate pathogenic factors, a surname's clearing the nasal passage, be used for due to wind-heat invading the lung, the retention of damp-heat in the interior nasal obstruction, rhinocnesmus gas heat, the watery nasal discharge Huang is thick or continue nasal obstruction, baryo,dmia; Chronic rhinitis, sinusitis are seen above-mentioned patient.
For beneficial effect of the present invention better is described, we have carried out clinical experimental study:
1, clinical data
Chronic rhinitis, sinusitis patient's 48 examples, male 23 examples, women 25 examples are divided into matched group and treatment and organize two groups, the age between 8～52 years old, average 30 years old; The course of disease 1～20 year.Nasal obstruction person's 18 examples are arranged, pus tears person 16 examples are arranged, vexed pain person's 7 examples of forehead are arranged, companion's deafness bulge of the ear person 5 examples, tears blood person 3 examples; X sheet prompting nasal sinuses has scorching change person's 12 examples; Find swollen person's 5 examples of concha nasalis inferior during inspection, nasal meatus empyema person 15 examples.Two groups of clinical datas such as sex, age, the course of disease, clinical symptoms, sign and the change of X sheet are learned by statistics to handle and are not all had significant difference (P＞0.05), have comparability.
2, Therapeutic Method
(1) matched group: BIYANKANG, usage and dosage: oral, each 2, every day 3 times.7 was 1 course of treatment.
(2) treatment group: adopt tablet in treatment of the present invention, its medicine consists of: Radix Codonopsis 30g, and Rhizoma Atractylodis Macrocephalae 50g, Radix Angelicae Dahuricae 40g, Herba Asari 45g, Fructus Gardeniae 60g, Flos Magnoliae 80g, Folium Eriobotryae 60g, Radix Platycodonis 70g, Pericarpium Granati 30g, Rhizoma Smilacis Glabrae 90g makes according to preparation method of the present invention.Usage and dosage: oral, each 2, every day 3 times, 7 is 1 course of treatment.
Two groups are not all used other any medicines during treating.
3, therapeutic outcome
(1) criterion of therapeutical effect
Clinical recovery: clinical symptom disappearance, training inspection see that concha nasalis dwindles, and the nasal meatus endocrine disappears;
Produce effects: clinical symptoms is most of to disappear, and training checks that concha nasalis obviously dwindles, and nasal meatus endocrine major part disappears;
Effectively: clinical symptoms partly disappears, and the training inspection sees that concha nasalis dwindles slightly, and the nasal meatus endocrine reduces;
Invalid: clinical symptoms does not have improvement, and the training inspection sees that concha nasalis and nasal meatus endocrine do not have change.
(2) therapeutic outcome (seeing the following form)
Table two group therapeutic outcome and curative effect are relatively
Annotate: compare * P＜0.05 with matched group
4, conclusion
Through preliminary clinical experimental study, tablet of the present invention is 95.58% to chronic rhinitis, sinusitis effective percentage.Shown that tablet of the present invention has significant clinical efficacy, and curative effect is better than BIYANKANG.
The specific embodiment of form is described in further detail foregoing of the present invention by the following examples.Following example is based on the above-mentioned subject area of the present invention, but is not limited to following example.
The specific embodiment
Embodiment 1:
Adopt following proportioning Chinese prescription:
Radix Codonopsis 30g Rhizoma Atractylodis Macrocephalae 50g Radix Angelicae Dahuricae 40g
Herba Asari 45g Fructus Gardeniae 60g Flos Magnoliae 80g
Folium Eriobotryae 60g Radix Platycodonis 70g Pericarpium Granati 30g
Rhizoma Smilacis Glabrae 90g
Its preparation technology may further comprise the steps:
Step 1: get Radix Codonopsis 30g, Rhizoma Atractylodis Macrocephalae 50g, Radix Angelicae Dahuricae 40g, Herba Asari 45g, mix, add alcohol reflux 2 times, each 1.5 hours, filter (medicinal residues are standby), decompression filtrate recycling ethanol is to extractum, and drying is pulverized, and sieves, and gets the ethanol extract fine powder, and is standby;
Step 2: Six-elements such as above-mentioned alcohol extraction medicinal residues and all the other Fructus Gardeniaes are mixed, decoct with water 3 times, each 1 hour, filter, filtrate is concentrated into the thick paste that relative density is 1.24 (70 ℃), drying is pulverized, sieve, the water extract fine powder, standby;
Step 3: the ethanol extract fine powder and the water extracting alcohol hypostasis fine powder that make is mixed, and the adding lactose is an amount of, and mixing is granulated, and compacting is in blocks, promptly.
Embodiment 2:
Adopt following proportioning Chinese prescription:
Radix Codonopsis 45g Rhizoma Atractylodis Macrocephalae 60g Radix Angelicae Dahuricae 50g
Herba Asari 50g Fructus Gardeniae 90g Flos Magnoliae 110g
Folium Eriobotryae 90g Radix Platycodonis 80g Pericarpium Granati 45g
Rhizoma Smilacis Glabrae 105g
Its preparation technology may further comprise the steps:
Step 1: get Radix Codonopsis 45g, Rhizoma Atractylodis Macrocephalae 60g, Radix Angelicae Dahuricae 50g, Herba Asari 50g, mix, add alcohol reflux 3 times, each 1 hour, filter (medicinal residues are standby), decompression filtrate recycling ethanol is to extractum, and drying is pulverized, and sieves, and gets the ethanol extract fine powder, and is standby;
Step 2: Six-elements such as above-mentioned alcohol extraction medicinal residues and all the other Fructus Gardeniaes are mixed, decoct with water 4 times, each 1 hour, filter, filtrate is concentrated into the thick paste that relative density is 1.22 (70 ℃), drying is pulverized, sieve, the water extract fine powder, standby;
Step 3: the ethanol extract fine powder and the water extracting alcohol hypostasis fine powder that make is mixed, and the adding dextrin is an amount of, and mixing is granulated, and compacting is in blocks, promptly.
Embodiment 3:
Adopt following proportioning Chinese prescription:
Radix Codonopsis 15g Rhizoma Atractylodis Macrocephalae 25g Radix Angelicae Dahuricae 20g
Herba Asari 15g Fructus Gardeniae 30g Flos Magnoliae 40g
Folium Eriobotryae 30g Radix Platycodonis 40g Pericarpium Granati 10g
Rhizoma Smilacis Glabrae 40g
Its preparation technology may further comprise the steps:
Step 1: get Radix Codonopsis 15g, Rhizoma Atractylodis Macrocephalae 25g, Radix Angelicae Dahuricae 20g, Herba Asari 15g, mix, add alcohol reflux 2 times, each 1 hour, filter (medicinal residues are standby), decompression filtrate recycling ethanol is to extractum, and drying is pulverized, and sieves, and gets the ethanol extract fine powder, and is standby;
Step 2: Six-elements such as above-mentioned alcohol extraction medicinal residues and all the other Fructus Gardeniaes are mixed, decoct with water 2 times, each 1 hour, filter, filtrate is concentrated into the thick paste that relative density is 1.26 (70 ℃), drying is pulverized, sieve, the water extract fine powder, standby;
Step 3: the ethanol extract fine powder and the water extracting alcohol hypostasis fine powder that make is mixed, and the adding dextrin is an amount of, and mixing is granulated, and compacting is in blocks, promptly.
Claims (4)
1. Chinese patent medicine for the treatment of chronic rhinitis, sinusitis is characterized in that it is that raw material is made by following parts by weight of Chinese traditional medicine material:
Radix Codonopsis 10～50 weight portion Rhizoma Atractylodis Macrocephalaes 20～70 weight portion Radixs Angelicae Dahuricae 20～60 weight portions
Herba Asari 15～60 weight portion Fructus Gardeniaes 30～90 weight portion Flos Magnoliaes 40～120 weight portions
Folium Eriobotryae 30～90 weight portion Radix Platycodoniss 40～90 weight portion Pericarpium Granatis 10～50 weight portions
Rhizoma Smilacis Glabrae 40～120 weight portions.
2. a kind of Chinese patent medicine for the treatment of chronic rhinitis, sinusitis according to claim 1, wherein the weight portion proportioning of each Chinese crude drug raw material is:
The Radix Codonopsis 30 weight portion Rhizoma Atractylodis Macrocephalaes 50 weight portion Radixs Angelicae Dahuricae 40 weight portions
Herba Asari 45 weight portion Fructus Gardeniaes 60 weight portion Flos Magnoliaes 80 weight portions
Folium Eriobotryae 60 weight portion Radix Platycodoniss 70 weight portion Pericarpium Granatis 30 weight portions
Rhizoma Smilacis Glabrae 90 weight portions.
3. according to each described a kind of Chinese patent medicine for the treatment of chronic rhinitis, sinusitis of claim 1-2, its preparation technology may further comprise the steps:
Step 1: get Radix Codonopsis, the Rhizoma Atractylodis Macrocephalae, the Radix Angelicae Dahuricae, Herba Asari, mix, add alcohol reflux, filter (medicinal residues are standby), decompression filtrate recycling ethanol is to extractum, and drying is pulverized, and sieves, and gets the ethanol extract fine powder, and is standby;
Step 2: Six-elements such as above-mentioned alcohol extraction medicinal residues and all the other Fructus Gardeniaes are mixed, decoct with water, filter, filtrate is concentrated into the thick paste that relative density is 1.22～1.26 (70 ℃), and drying is pulverized, sieve, the water extract fine powder, standby;
Step is mixed with the ethanol extract fine powder and the water extracting alcohol hypostasis fine powder that make, adds suitable proper quantity of medicinal auxiliary material, and mixing is granulated, and suppresses in flakes, promptly.
4. according to each described a kind of Chinese patent medicine for the treatment of chronic rhinitis, sinusitis of claim 1-2, its function cures mainly and is: have the function of heat-clearing and toxic substances removing, strengthening vital QI to eliminate pathogenic factors, a surname's clearing the nasal passage, be used for due to wind-heat invading the lung, the retention of damp-heat in the interior nasal obstruction, rhinocnesmus gas heat, the watery nasal discharge Huang is thick or continue nasal obstruction, baryo,dmia; Chronic rhinitis, sinusitis are seen above-mentioned patient.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200810240981 CN101766749A (en) | 2008-12-26 | 2008-12-26 | Chinese patent medicine for treating chronic rhinitis and nasosinusitis |
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| Application Number | Priority Date | Filing Date | Title |
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| CN 200810240981 CN101766749A (en) | 2008-12-26 | 2008-12-26 | Chinese patent medicine for treating chronic rhinitis and nasosinusitis |
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| CN101766749A true CN101766749A (en) | 2010-07-07 |
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| CN 200810240981 Pending CN101766749A (en) | 2008-12-26 | 2008-12-26 | Chinese patent medicine for treating chronic rhinitis and nasosinusitis |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103638140A (en) * | 2013-12-17 | 2014-03-19 | 黄书芳 | Medicament for treating rhinitis |
| CN104922272A (en) * | 2015-05-29 | 2015-09-23 | 陈永泉 | Traditional Chinese medicine for treating rhinitis |
-
2008
- 2008-12-26 CN CN 200810240981 patent/CN101766749A/en active Pending
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103638140A (en) * | 2013-12-17 | 2014-03-19 | 黄书芳 | Medicament for treating rhinitis |
| CN104922272A (en) * | 2015-05-29 | 2015-09-23 | 陈永泉 | Traditional Chinese medicine for treating rhinitis |
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Open date: 20100707 |