CN101762711A - Method and device for judging water blank value and monitoring method using biochemical analyzer and cleaning needle - Google Patents
Method and device for judging water blank value and monitoring method using biochemical analyzer and cleaning needle Download PDFInfo
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- CN101762711A CN101762711A CN200810241824A CN200810241824A CN101762711A CN 101762711 A CN101762711 A CN 101762711A CN 200810241824 A CN200810241824 A CN 200810241824A CN 200810241824 A CN200810241824 A CN 200810241824A CN 101762711 A CN101762711 A CN 101762711A
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Abstract
The invention discloses a method and a device for judging water blank value, which is applicable for judging whether the water blank value of the reaction cup measured by a biochemical analyzer is abnormal. The method includes: obtaining the measured water blank value of the reaction cup; obtaining the empty cup value measured of the reaction cup at the period of wiping the biochemical analyzer; comparing the water blank value of the reaction cup with the empty cup value according to a judging condition, and determining whether the water blank value of the reaction cup is abnormal according to the comparison result. The invention compares the relation of the water blank value of the reaction cup and the measurement value of the wiping cleansing position by a judgment formula, finally determines whether the water blank value of the reaction cup is abnormal. The invention can ensure the correctness of the water blank value involved in absorbance calculation, thus preventing the apparatus from generating wrong test results. The method for judging water blank value is reliable and convenient.
Description
[technical field]
The present invention relates to Biochemical Analyzer, relate in particular to the determination methods and the judgment means of the water blank value of Biochemical Analyzer.
[background technology]
Automatic biochemistry analyzer is used to the analysis of Biosample target component concentration, for example, and blood or urine samples such as protein, flesh liver, cholesterol.Except the biochemical instruments of using disposal reaction cup, the reaction cup of most of Biochemical Analyzers all needs to be cleaned and to reuse after finishing sample analysis.
Biochemical Analyzer is made up of photometric measurement unit, automatic cleaning unit, reaction tray unit, specimen needle unit, reagent needles unit, master control borad unit etc.In Biochemical Analyzer, the absorbance computing formula of reaction mixture is:
Wherein, AD
0Be the water blank value of reaction cup, reaction cup water blank value is for injecting the AD value that records behind the deionized water, AD to reaction cup
SecretlyFor illuminator is closed the AD value that records under the situation, AD
iBe the AD value of the reaction mixture that records, wherein the AD value is converted into the numerical value of digital signal for the simulating signal of measured result.Work as AD
0Occur unusually, then mistake will appear in the absorbance A test result of reaction mixture.The principle of photometric measurement unit is that the light that light source sends shines on the photodetector by reaction cup, thereby realize that light signal is to electrical signal conversion, by preceding discharge road signal is amplified again, and realize that by the AD chip simulating signal changes to digital signal, the light intensity value that sees through after the reaction cup can be represented with the AD value of AD chip output.At present, the common method of obtaining reaction cup water blank value is: utilize AD value that automatic cleaning unit single order cleaning needle records after reaction cup the is injected deionized water water blank value as this reaction cup, not but normally whether not judging of water blank, in the practice, when cleaning needle on the reaction cup optical direction, producing after the reaction cup water filling when having bubble or this cleaning needle problem such as water injection rate deficiency to occur, the measured value of reaction cup water blank will be unusual, when obtaining unusual water blank value, instrument itself is not also known, if adopt the blank value of unusual measured value as reaction cup, this can cause the instrument test result to make mistakes.
[summary of the invention]
The main technical problem to be solved in the present invention is, a kind of determination methods and device of water blank value is provided, and whether the reaction cup water blank value of test is judged unusually.
Whether another technical matters that the present invention will solve is, a kind of Biochemical Analyzer is provided, can judge unusually the reaction cup water blank value of test, thereby avoid causing the test result mistake unusually because of the water blank value.
The another technical matters that the present invention will solve is, a kind of cleaning needle method for supervising is provided, and cleaning needle is monitored, and prevents that cleaning needle is unusual.
For solving the problems of the technologies described above, the invention provides a kind of determination methods of water blank value, whether the reaction cup water blank value that is used for Biochemical Analyzer is recorded is judged unusually, comprising:
Obtain the reaction cup water blank value that records;
Obtain the empty cup value that reaction cup records on the wiping rank of Biochemical Analyzer;
Reaction cup water blank value and empty cup value are compared according to Rule of judgment, and determine according to comparative result whether reaction cup water blank value is unusual.
The present invention also provides a kind of judgment means of water blank value, and whether the reaction cup water blank value that is used for Biochemical Analyzer is recorded is judged unusually, comprising: first module that is used to obtain the reaction cup water blank value that records; Be used to obtain second module of the empty cup value that reaction cup records on the wiping rank of Biochemical Analyzer; Be used for a reaction cup water blank value and an empty cup value are compared according to Rule of judgment, and determine the three module that reaction cup water blank value is whether unusual according to comparative result.
The present invention also provides a kind of Biochemical Analyzer, comprising: the reaction tray unit is mounted with reaction cup on it; Cleaning unit is used for reaction cup is cleaned; The photometric measurement unit is used for the reaction cup that moves in the measurement range is tested, and outputs test result; Main control unit, be used for the test result of photometric measurement unit output is handled, described main control unit also is used to obtain the reaction cup water blank value that the photometric measurement unit records and obtains the empty cup value that reaction cup records on the wiping rank of Biochemical Analyzer, and a reaction cup water blank value and an empty cup value compared according to Rule of judgment, determine according to comparative result whether reaction cup water blank value is unusual.
The present invention also provides a kind of cleaning needle method for supervising, is used for whether the cleaning needle of Biochemical Analyzer is normally monitored, and comprising:
Obtain the reaction cup AD value that the X rank record;
Obtain the empty cup value that reaction cup records on the wiping rank of Biochemical Analyzer;
A reaction cup AD value that the X rank are recorded and an empty cup value compare according to Rule of judgment, and determine according to comparative result whether the reaction cup AD value that the X rank record is unusual;
Surpass setting threshold if occur the quantity of unusual reaction cup continuously, think that then this X rank cleaning needle is unusual.
The invention has the beneficial effects as follows: the present invention determines finally by the relation of the test value of judgment formula comparison reaction cup water blank value and wiping cleaning position whether reaction cup water blank value is normal.Can guarantee to participate in the correctness of the water blank value that absorbance calculates, thereby avoid instrument the test result mistake to occur.The determination methods of this water blank value is reliable, convenient.In addition, whether normal by continuous monitoring reaction cup water blank value, thus realization guarantees that to the monitoring of automatic cleaning unit cleaning needle duty cleaning unit normally uses.
[description of drawings]
Fig. 1 is a kind of structural representation of Biochemical Analyzer;
Fig. 2 is the functional-block diagram of the device of an embodiment of the present invention;
Fig. 3 is the process flow diagram of an embodiment of the present invention;
Fig. 4 is the process flow diagram of the another kind of embodiment of the present invention;
Fig. 5 is the process flow diagram of another embodiment of the present invention.
[embodiment]
The application's feature and advantage will be elaborated in conjunction with the accompanying drawings by embodiment.
Please refer to Fig. 1, Biochemical Analyzer comprises reaction tray unit 8, cleaning unit 1, photometric measurement unit 6 and main control unit 9.Be mounted with reaction cup 4 on the reaction tray unit 8, can drive the reaction cup rotation.The fluid injection unit is used for after reaction cup 4 rotates to the application of sample position injecting sample and/or reagent in reaction cup.Cleaning unit 1 is used for after reaction cup 4 rotates to the cleaning position reaction cup 4 being cleaned, and single order or multistage cleaning can be arranged.Photometric measurement unit 6 is used for the AD value is tested and exported to the reaction cup that moves in the measurement range, and photometric measurement unit 6 comprises light source 5 and divides photodetection assembly 7.The light that light source 5 sends shines on the photodetector by reaction cup, divide photodetection assembly 7 to collect light signal, realize that light signal is to electrical signal conversion, by preceding discharge road signal is amplified again, and realize that by the AD chip simulating signal changes to digital signal, the light intensity value that sees through after the reaction cup can be represented with the AD value of AD chip output.Main control unit 9 is used for the AD value of photometric measurement unit 6 outputs is handled, comprising obtaining the reaction cup water blank value that photometric measurement unit 6 records and obtaining the empty cup value that reaction cup records on the wiping rank of Biochemical Analyzer, and a reaction cup water blank value and an empty cup value compared according to Rule of judgment, determine according to comparative result whether reaction cup water blank value is unusual.
Please refer to Fig. 2, in one embodiment, the judgment means of water blank value comprises first module, second module and three module.First module is used to obtain the reaction cup water blank value that records, second module is used to obtain the empty cup value that reaction cup records on the wiping rank of Biochemical Analyzer, three module is used for reaction cup water blank value and empty cup value are compared according to Rule of judgment, and determines according to comparative result whether reaction cup water blank value is unusual.
The judgment means of water blank value can further include four module in another kind of embodiment, four module is used for skipping in the biochemical analysis process at this abnormal response cup of the unusual back control of definite reaction cup water blank value need not, avoid the reaction cup that the water blank value is unusual to be used for test, thereby avoid causing unusually the test result mistake of Biochemical Analyzer because of the water blank value.
Above-mentioned first module, second module, three module and four module can be realized by discrete parts, also can be integrated in the main control unit, realize by microprocessor embedded software or other integrated circuit.
Please refer to Fig. 3, based on said apparatus, in one embodiment, the determination methods of water blank value may further comprise the steps:
(AD
0-AD
Empty-Δ AD)/AD
0〉=L1;
AD
0-AD
Empty〉=L2;
(AD
0-AD
Empty-Δ AD) 〉=L3;
(AD
0-AD
Empty)/AD
0〉=L4;
AD
0+ AD
Empty〉=L5;
Think that when condition satisfies reaction cup water blank value is normal, otherwise think that reaction cup water blank value is unusual, wherein, AD
0Be reaction cup water blank value, AD
EmptyBe the empty cup value of reaction cup, Δ AD for the reaction cup of this kind material in the difference that AD value that records under the deionized water situation and the AD value that records under empty glass situation are housed, the AD value is converted into the numerical value of digital signal for the simulating signal of measured result, L1 is a first threshold, L2 is second threshold value, L3 is the 3rd threshold value, and L4 is the 4th threshold value, and L5 is the 5th threshold value.
In another embodiment, skipping in the biochemical analysis process at this abnormal response cup of the unusual back control of definite reaction cup water blank value need not.
In the foregoing description, the order of step 102 and step 104 also can be changed, and promptly obtains the empty cup value that reaction cup records on the wiping rank of Biochemical Analyzer earlier, obtains the reaction cup water blank value that records again.
Automatically cleaning unit is in the process of cleaning reaction cup, its certain single order cleaning needle can produce bubble once in a while in the process of reaction cup fluid injection or imbibition, and bubble sticks on the optical surface of reaction cup sometimes, cause this reaction cup water blank value to diminish and occur unusually, the automatic cleaning unit cleaning needle that perhaps is used to obtain reaction cup water blank occurs unusually can not be when reaction cup water filling or water injection rate be not enough, reaction cup water blank value also can diminish and occur unusually, compare by the AD value that records under the water blank value that will record and the empty cup situation, if both is poor, with or rate of change within the specific limits, can think that then the water blank value is normal, if exceed certain limit, think that then the water blank value is unusual.And reaction cup water blank value may cause instrument to give the test result that makes mistake unusually.Take whether normal judgement then can avoid obtaining unusual water blank under the following situation: can avoid having obtained unusual water blank value owing to cleaning needle goes wrong to the water blank value; Can avoid automatic cleaning unit cleaning needle when the reaction cup water filling produces bubble or cleaning needle and unusual not water filling occurs and obtain unusual water blank.
Each work period, reaction tray is carried out the photooptical data collection in the process of rotation, and reaction cup needs to clean when test, and according to the cleaning needle quantity of concrete Biochemical Analyzer configuration, reaction cup is through repeatedly cleaning.In test process, a certain reaction cup can forward the cleaning needle position, the 1st rank of automatic cleaning unit, the pipette of cleaning needle and liquid injection pipe work at this moment according to sequential to, the cleaning of realization response cup, after cleaning was finished, the reaction tray rotation was carried out the photooptical data collection to reaction cup in the process of rotation; Then reaction cup is gone forward one by one successively, carry out that the 2nd rank are cleaned, the 3rd rank are cleaned ....Automatically have single order or multistage cleaning needle to have the wiping head in the cleaning unit, be used for wiping away the residuary water of dry reaction cup, such cleaning needle is called the wiping cleaning needle, and the arrangement position of wiping cleaning needle can be different.After every rank are cleaned and are finished all can to carry out the photooptical data collection clean finish after by a wiping wiped clean.Reaction cup is finished cleaning after cleaning through the M rank, the M rank are the wiping rank, be cleaned totally and clean the afterreaction cup on (M-N) rank, the AD value that records with (M-N) rank is as the water blank value of this reaction cup (all can adopt AD value that specific cleaning rank the record water blank value as this reaction cup) in each Biochemical Analyzer, wherein M, N are integers.The AD value and the water blank value that utilize wiping rank (for example M rank) to record compare to judge the correctness of water blank value.Rule of judgment can be in the following condition any:
(AD
0-AD
Empty-Δ AD)/AD
0〉=L1;
AD
0-AD
Empty〉=L2;
(AD
0-AD
Empty-Δ AD) 〉=L3;
(AD
0-AD
Empty)/AD
0〉=L4;
AD
0+ AD
Empty〉=L5;
Think that when condition satisfies reaction cup water blank value is normal, otherwise think that reaction cup water blank value is unusual, wherein, AD
0Be reaction cup water blank value, AD
EmptyBe the empty cup value of reaction cup, Δ AD for the reaction cup of this kind material in the difference that AD value that records under the deionized water situation and the AD value that records under empty glass situation are housed, for the reaction cup of same material, Δ AD is a steady state value.The AD value is the numerical value that the simulating signal of measured result is converted into digital signal, and L1 is a first threshold, and L2 is second threshold value, and L3 is the 3rd threshold value, and L4 is the 4th threshold value, and L5 is the 5th threshold value, and these threshold values can be according to the real needs setting of instrument clinical trial project.For example, after reaction cup was finished all cleanings, the water blank value and the reaction cup AD value that (wiping rank) record on the M rank that can adopt reaction cup to record in (M-N) cleaning position, rank compared, as (AD
(M-N)-AD
M-Δ AD)/AD
(M-N)When 〉=L1 sets up, show that the water blank value that obtains when reaction cup is cleaned in (M-N) cleaning position, rank is normal, otherwise this water blank value is unusual.For the unusual reaction cup of water skip test, give water outlet blank abnormal alarm information, skip need not for this reaction cup simultaneously.Wherein, AD
MThe AD value that records of expression cleaning position, wiping rank, it can be the AD value that single wiping rank record, and also can be the mean value of the AD value that records of a plurality of wipings rank.
Be that example describes with eight rank cleaning needles below.
Please refer to Fig. 1, automatically cleaning unit 1 is made up of eight rank cleaning needles, 7th, 8 rank cleaning needles 2 have wiping 3, each rank cleaning needle is made up of fluid injection pin and aspirating needle, wherein 1～2 rank are to clean with clean-out system, and 4～6 rank are to use washed with de-ionized water, 7～8 rank be wipe away dried, in the present embodiment, the 6th rank are used to obtain the water blank.Each work period that reaction cup 4 is cleaned, reaction tray unit 8 drives reaction cup 4 rotations, carries out photooptical data collection and storage in 6 positions, photometric measurement unit.Reaction cup is then gone forward one by one after finishing the cleaning of the 1st rank successively, carries out the 2nd rank, the 3rd rank, the 4th rank, the 5th rank, the cleaning of the 6th rank, the 7th rank and the 8th rank wiping, and photooptical data collection and storage all can be carried out after cleaning in every rank.
Its process flow diagram as shown in Figure 4.After the test beginning, reaction cup is carried out and is cleaned, and from 8 rank, the 1st rank to the, the AD value of each work period all wavelengths all can be recorded successively.Finish after the 6th rank clean when reaction cup, find out the AD value of reaction cup the 6th all passages of rank,,, show that water blank value AD6 is normal if when (AD6-AD8-Δ AD)/AD6 〉=-1.0% is set up for a certain passage, otherwise unusually.
In like manner, also can adopt other Rule of judgment, the empty cup value that also can adopt the 7th rank (wiping rank) to record is judged.
The passage that with the wavelength is 340nm is an example, if automatically the cleaning needle of cleaning unit is not when problem such as bubble or water filling deficiency occurring in the reaction cup the injecting process, the AD value that cleaning position, the 6th rank records after cleaning is: AD6=42467, and AD8=40420, Δ AD=2000, at this moment (AD6-AD8-Δ AD)/AD6=0.1%＞-1.0%, satisfy Rule of judgment, therefore can judge that AD value that the 6th rank record normally, can be used as the water blank value of this reaction cup, i.e. AD
Water blank (340)=AD6
(340)=42467, and this reaction cup can be carried out clinical trial.If the 6th rank cleaning needle of cleaning unit is having the bubble of generation and is sticking on the optical surface in the reaction cup the injecting process automatically, AD6=32467 then, and AD8=40420, Δ AD=2000, therefore at this moment (AD6-AD8-Δ AD)/AD6=-30.6%＜-1.0% does not satisfy Rule of judgment, can judge that AD value that this reaction cup records on the 6th rank unusually, at this moment system will provide the blank unusual warning message of reaction cup water, and this reaction cup will not be used to test.As seen by comparison, can effectively avoid obtaining unusual water blank value with the 8th rank test value and the 6th rank water blank value.
The judgment threshold that below according to circumstances provides (AD6-AD8-Δ AD)/AD6 is-1%, and in fact under the different operating condition, this judgment threshold can be other value.In addition, the AD value that above situation provides, it only is a kind of expression mode of signal, it can be light intensity value, analog signal values or digital signal value etc.
In another embodiment, whether normal by continuous monitoring reaction cup water blank value, thus realization is to the monitoring of automatic cleaning unit cleaning needle duty.Its process flow diagram as shown in Figure 5.After the test beginning, reaction cup is carried out and is cleaned, and from 8 rank, the 1st rank to the, the AD value of each cycle all wavelengths all can be recorded successively.Finish after the 8th rank clean when reaction cup, find out the AD value of reaction cup the 6th rank and the 8th all passages of rank,,, show that the 6th rank cleaning needle is working properly, otherwise cleaning needle may be unusually if when (AD6-AD8-Δ AD)/AD6 〉=-1.0% is set up for a certain passage.The passage that with the wavelength is 340nm is an example, under the normal condition, and AD6=42467, AD8=40445, Δ AD=2000, at this moment at this moment (AD6-AD8-Δ AD)/AD6=0.05%＞-1.0% can judge that the 6th rank cleaning needle is working properly; Under the abnormal conditions, AD6=32467, AD8=40445, Δ AD=2000, at this moment (AD6-AD8-Δ AD)/AD6=-30.7%＜-1.0%, at this moment the 6th rank cleaning needle may operation irregularity, and instrument then carries out the cleaning of next reaction cup, is false if above-mentioned Rule of judgment appears in continuous 4 reaction cup, at this moment, system provides warning message, and it is unusual to tell that this rank cleaning needle of operator occurs, and suggestion operations person checks.
Below according to circumstances by test the comparison of the AD value of AD value and the test of cleaning position, the 6th rank with the cleaning position, the 8th rank of 340nm passage, detect thereby the 6th rank cleaning needle is carried out abnormal state, in fact also can carry out abnormal state with other passage to this cleaning needle separately and detect.
In like manner, by the monitoring of AD value that other rank are recorded, also can carry out abnormal state and detect other rank cleaning needle.
Provide automatic cleaning structure abnormal alarm information when below according to circumstances adopting continuous 4 reaction cup to occur not satisfying Rule of judgment, in fact also can adopt to occur not satisfying Rule of judgment more than a reaction cup continuously and provide warning message.
The present invention passes through the test value of record reaction cup after each cleaning position of cleaning unit is cleaned automatically earlier, compares the relation of the test value of reaction cup water blank value and other cleaning position then by judgment formula, determines finally whether reaction cup water blank value is normal.This measured value after other cleaning position is cleaned and the determination methods of reaction cup water blank value comparison utilized can effectively avoid obtaining unusual water blank value, can guarantee to participate in the correctness of the water blank value that absorbance calculates, thereby avoid instrument the test result mistake to occur.The determination methods of this water blank value is reliable, convenient.In addition, whether normal by continuous monitoring reaction cup water blank value, thus realization guarantees that to the monitoring of automatic cleaning unit cleaning needle duty cleaning unit normally uses.
Above content be in conjunction with concrete preferred implementation to further describing that the present invention did, can not assert that concrete enforcement of the present invention is confined to these explanations.For the general technical staff of the technical field of the invention, without departing from the inventive concept of the premise, can also make some simple deduction or replace, all should be considered as belonging to protection scope of the present invention.
Claims (12)
1. the determination methods of a water blank value, whether the reaction cup water blank value that is used for Biochemical Analyzer is recorded is judged unusually, it is characterized in that comprising:
Obtain the reaction cup water blank value that records;
Obtain the empty cup value that reaction cup records on the wiping rank of Biochemical Analyzer;
Reaction cup water blank value and empty cup value are compared according to Rule of judgment, and determine according to comparative result whether reaction cup water blank value is unusual.
2. determination methods as claimed in claim 1 is characterized in that: described Rule of judgment is any in the following condition:
(AD
0-AD
Empty-Δ AD)/AD
0〉=L1;
AD
0-AD
Empty〉=L2;
(AD
0-AD
Empty-Δ AD) 〉=L3;
(AD
0-AD
Empty)/AD
0〉=L4;
AD
0+ AD
Empty〉=L5;
Think that when condition satisfies reaction cup water blank value is normal, otherwise think that reaction cup water blank value is unusual, wherein, AD
0Be reaction cup water blank value, AD
EmptyBe the empty cup value of reaction cup, Δ AD for the reaction cup of this kind material in the difference that AD value that records under the deionized water situation and the AD value that records under empty glass situation are housed, the AD value is converted into the numerical value of digital signal for the simulating signal of measured result, L1 is a first threshold, L2 is second threshold value, L3 is the 3rd threshold value, and L4 is the 4th threshold value, and L5 is the 5th threshold value.
3. determination methods as claimed in claim 1 is characterized in that: the described empty cup value that records on the wiping rank of Biochemical Analyzer is the empty glass value that records or the mean value of a plurality of wipings rank measured result on single wiping rank.
4. as each described determination methods in the claim 1 to 3, it is characterized in that: skipping in the biochemical analysis process at this abnormal response cup of the unusual back control of definite reaction cup water blank value need not.
5. a cleaning needle method for supervising is used for whether the cleaning needle of Biochemical Analyzer is normally monitored, and it is characterized in that comprising:
Obtain the reaction cup AD value that the X rank record;
Obtain the empty cup value that reaction cup records on the wiping rank of Biochemical Analyzer;
A reaction cup AD value that the X rank are recorded and an empty cup value compare according to Rule of judgment, and determine according to comparative result whether the reaction cup AD value that the X rank record is unusual;
Surpass setting threshold if occur the quantity of unusual reaction cup continuously, think that then this X rank cleaning needle is unusual.
6. the judgment means of a water blank value, whether the reaction cup water blank value that is used for Biochemical Analyzer is recorded is judged unusually, it is characterized in that comprising:
Be used to obtain first module of the reaction cup water blank value that records;
Be used to obtain second module of the empty cup value that reaction cup records on the wiping rank of Biochemical Analyzer;
Be used for a reaction cup water blank value and an empty cup value are compared according to Rule of judgment, and determine the three module that reaction cup water blank value is whether unusual according to comparative result.
7. judgment means as claimed in claim 6 is characterized in that: described Rule of judgment is any in the following condition:
(AD
0-AD
Empty-Δ AD)/AD
0〉=L1;
AD
0-AD
Empty〉=L2;
(AD
0-AD
Empty-Δ AD) 〉=L3;
(AD
0-AD
Empty)/AD
0〉=L4;
AD
0+ AD
Empty〉=L5;
Think that when condition satisfies reaction cup water blank value is normal, otherwise think that reaction cup water blank value is unusual, wherein, AD
0Be reaction cup water blank value, AD
EmptyBe the empty cup value of reaction cup, Δ AD for the reaction cup of this kind material in the difference that AD value that records under the deionized water situation and the AD value that records under empty glass situation are housed, the AD value is converted into the numerical value of digital signal for the simulating signal of measured result, L1 is a first threshold, L2 is second threshold value, L3 is the 3rd threshold value, and L4 is the 4th threshold value, and L5 is the 5th threshold value.
8. judgment means as claimed in claim 6 is characterized in that: the described empty cup value that records on the wiping rank of Biochemical Analyzer is the empty glass value that records or the mean value of a plurality of wipings rank measured result on single wiping rank.
9. as each described judgment means in the claim 6 to 8, it is characterized in that: also comprise being used for skipping no four module in the biochemical analysis process at this abnormal response cup of the unusual back control of definite reaction cup water blank value.
10. Biochemical Analyzer comprises:
The reaction tray unit is mounted with reaction cup on it;
Cleaning unit is used for reaction cup is cleaned;
The photometric measurement unit is used for the reaction cup that moves in the measurement range is tested, and outputs test result;
Main control unit, be used for the test result of photometric measurement unit output is handled, it is characterized in that: described main control unit also is used to obtain the reaction cup water blank value that the photometric measurement unit records and obtains the empty cup value that reaction cup records on the wiping rank of Biochemical Analyzer, and a reaction cup water blank value and an empty cup value compared according to Rule of judgment, determine according to comparative result whether reaction cup water blank value is unusual.
11. Biochemical Analyzer as claimed in claim 10 is characterized in that: described Rule of judgment is any in the following condition:
(AD
0-AD
Empty-Δ AD)/AD
0〉=L1;
AD
0-AD
Empty〉=L2;
(AD
0-AD
Empty-Δ AD) 〉=L3;
(AD
0-AD
Empty)/AD
0〉=L4;
AD
0+ AD
Empty〉=L5;
Think that when condition satisfies reaction cup water blank value is normal, otherwise think that reaction cup water blank value is unusual, wherein, AD
0Be reaction cup water blank value, AD
EmptyBe the empty cup value of reaction cup, Δ AD for the reaction cup of this kind material in the difference that AD value that records under the deionized water situation and the AD value that records under empty glass situation are housed, the AD value is converted into the numerical value of digital signal for the simulating signal of measured result, L1 is a first threshold, L2 is second threshold value, L3 is the 3rd threshold value, and L4 is the 4th threshold value, and L5 is the 5th threshold value.
12. as claim 10 or 11 described Biochemical Analyzers, it is characterized in that: described main control unit also is used for skipping in the biochemical analysis process at this abnormal response cup of the unusual back control of definite reaction cup water blank value need not.
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| CN 200810241824 CN101762711B (en) | 2008-12-19 | 2008-12-19 | Method and device for judging water blank value and monitoring method using biochemical analyzer and cleaning needle |
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|---|---|---|---|
| CN 200810241824 CN101762711B (en) | 2008-12-19 | 2008-12-19 | Method and device for judging water blank value and monitoring method using biochemical analyzer and cleaning needle |
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| CN102507914A (en) * | 2011-10-28 | 2012-06-20 | 长春迪瑞医疗科技股份有限公司 | Device and method for checking blank of cup of biochemical analysis meter |
| CN109557027A (en) * | 2017-09-26 | 2019-04-02 | 深圳市新产业生物医学工程股份有限公司 | The detection method of container state in automatic analysing apparatus and its course of work |
| CN110596046A (en) * | 2018-06-12 | 2019-12-20 | 深圳市理邦精密仪器股份有限公司 | Reaction cup detection method and device based on laser scattering assembly and storage medium |
| CN113640256A (en) * | 2021-08-27 | 2021-11-12 | 重庆中元汇吉生物技术有限公司 | Water blank detection method, device, equipment and storage medium |
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2008
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| CN102507914A (en) * | 2011-10-28 | 2012-06-20 | 长春迪瑞医疗科技股份有限公司 | Device and method for checking blank of cup of biochemical analysis meter |
| CN102507914B (en) * | 2011-10-28 | 2013-12-04 | 长春迪瑞医疗科技股份有限公司 | Method for checking blank of cup of biochemical analysis meter |
| CN109557027A (en) * | 2017-09-26 | 2019-04-02 | 深圳市新产业生物医学工程股份有限公司 | The detection method of container state in automatic analysing apparatus and its course of work |
| CN109557027B (en) * | 2017-09-26 | 2022-09-02 | 深圳市新产业生物医学工程股份有限公司 | Automatic analysis device and detection method for container state in working process thereof |
| CN110596046A (en) * | 2018-06-12 | 2019-12-20 | 深圳市理邦精密仪器股份有限公司 | Reaction cup detection method and device based on laser scattering assembly and storage medium |
| CN110596046B (en) * | 2018-06-12 | 2023-06-13 | 深圳市理邦精密仪器股份有限公司 | Reaction cup detection method and device based on laser scattering component and storage medium |
| CN113640256A (en) * | 2021-08-27 | 2021-11-12 | 重庆中元汇吉生物技术有限公司 | Water blank detection method, device, equipment and storage medium |
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| CN101762711B (en) | 2013-05-08 |
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Application publication date: 20100630 Assignee: Shenzhen Mindray Animal Medical Technology Co.,Ltd. Assignor: SHENZHEN MINDRAY BIO-MEDICAL ELECTRONICS Co.,Ltd. Contract record no.: X2022440020009 Denomination of invention: Water blank value judgment method and device, biochemical analyzer and cleaning needle monitoring method Granted publication date: 20130508 License type: Common License Record date: 20220804 |