CN101611766A - A kind of production method of enteric-coated kitasamycin for feed - Google Patents
A kind of production method of enteric-coated kitasamycin for feed Download PDFInfo
- Publication number
- CN101611766A CN101611766A CN200910181418A CN200910181418A CN101611766A CN 101611766 A CN101611766 A CN 101611766A CN 200910181418 A CN200910181418 A CN 200910181418A CN 200910181418 A CN200910181418 A CN 200910181418A CN 101611766 A CN101611766 A CN 101611766A
- Authority
- CN
- China
- Prior art keywords
- kitasamycin
- enteric
- coating
- medicine carrying
- coated
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 229950007634 kitasamycin Drugs 0.000 title claims abstract description 47
- XYJOGTQLTFNMQG-KJHBSLKPSA-N leucomycin V Chemical compound CO[C@H]1[C@H](O)CC(=O)O[C@H](C)C\C=C\C=C\[C@H](O)[C@H](C)C[C@H](CC=O)[C@@H]1O[C@H]1[C@H](O)[C@@H](N(C)C)[C@H](O[C@@H]2O[C@@H](C)[C@H](O)[C@](C)(O)C2)[C@@H](C)O1 XYJOGTQLTFNMQG-KJHBSLKPSA-N 0.000 title claims abstract description 47
- 238000004519 manufacturing process Methods 0.000 title claims abstract description 10
- 239000011248 coating agent Substances 0.000 claims abstract description 26
- 238000000576 coating method Methods 0.000 claims abstract description 26
- 239000003814 drug Substances 0.000 claims abstract description 25
- 229920003088 hydroxypropyl methyl cellulose Polymers 0.000 claims abstract description 15
- 239000000463 material Substances 0.000 claims abstract description 13
- 238000013268 sustained release Methods 0.000 claims abstract description 12
- 239000012730 sustained-release form Substances 0.000 claims abstract description 12
- 235000010979 hydroxypropyl methyl cellulose Nutrition 0.000 claims abstract description 11
- 239000004925 Acrylic resin Substances 0.000 claims abstract description 8
- 229920000178 Acrylic resin Polymers 0.000 claims abstract description 8
- 239000002702 enteric coating Substances 0.000 claims abstract description 8
- 238000009505 enteric coating Methods 0.000 claims abstract description 8
- 239000003795 chemical substances by application Substances 0.000 claims abstract description 7
- 230000000968 intestinal effect Effects 0.000 claims abstract description 7
- 238000002360 preparation method Methods 0.000 claims abstract description 5
- 239000008280 blood Substances 0.000 claims abstract description 4
- 210000004369 blood Anatomy 0.000 claims abstract description 4
- 235000011389 fruit/vegetable juice Nutrition 0.000 claims abstract description 3
- 239000002245 particle Substances 0.000 claims description 7
- 239000007864 aqueous solution Substances 0.000 claims description 6
- 239000011122 softwood Substances 0.000 claims description 5
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 5
- 229920001353 Dextrin Polymers 0.000 claims description 4
- 239000004375 Dextrin Substances 0.000 claims description 4
- 241001676635 Lepidorhombus whiffiagonis Species 0.000 claims description 4
- 229920002472 Starch Polymers 0.000 claims description 4
- 235000009508 confectionery Nutrition 0.000 claims description 4
- 235000019425 dextrin Nutrition 0.000 claims description 4
- 238000000034 method Methods 0.000 claims description 4
- 235000019698 starch Nutrition 0.000 claims description 4
- 239000008107 starch Substances 0.000 claims description 4
- 238000005303 weighing Methods 0.000 claims description 4
- 239000001866 hydroxypropyl methyl cellulose Substances 0.000 claims 4
- UFVKGYZPFZQRLF-UHFFFAOYSA-N hydroxypropyl methyl cellulose Chemical compound OC1C(O)C(OC)OC(CO)C1OC1C(O)C(O)C(OC2C(C(O)C(OC3C(C(O)C(O)C(CO)O3)O)C(CO)O2)O)C(CO)O1 UFVKGYZPFZQRLF-UHFFFAOYSA-N 0.000 claims 4
- 210000002784 stomach Anatomy 0.000 abstract description 14
- 229940079593 drug Drugs 0.000 abstract description 8
- 230000000694 effects Effects 0.000 abstract description 6
- 244000000010 microbial pathogen Species 0.000 abstract description 5
- 239000000126 substance Substances 0.000 abstract description 5
- 230000003115 biocidal effect Effects 0.000 abstract description 4
- 239000008187 granular material Substances 0.000 abstract description 4
- 230000000638 stimulation Effects 0.000 abstract description 4
- 206010012735 Diarrhoea Diseases 0.000 abstract description 3
- 208000012895 Gastric disease Diseases 0.000 abstract description 3
- 206010047700 Vomiting Diseases 0.000 abstract description 3
- 239000002253 acid Substances 0.000 abstract description 3
- 150000007513 acids Chemical class 0.000 abstract description 3
- 210000004347 intestinal mucosa Anatomy 0.000 abstract description 3
- 238000009395 breeding Methods 0.000 abstract description 2
- 230000001488 breeding effect Effects 0.000 abstract description 2
- 239000000428 dust Substances 0.000 abstract description 2
- 239000011859 microparticle Substances 0.000 abstract description 2
- 239000003405 delayed action preparation Substances 0.000 abstract 1
- 210000004051 gastric juice Anatomy 0.000 abstract 1
- 241001465754 Metazoa Species 0.000 description 10
- 239000000203 mixture Substances 0.000 description 5
- 239000000843 powder Substances 0.000 description 4
- 235000019658 bitter taste Nutrition 0.000 description 3
- 230000002401 inhibitory effect Effects 0.000 description 3
- 241000894006 Bacteria Species 0.000 description 2
- 230000000844 anti-bacterial effect Effects 0.000 description 2
- 235000013305 food Nutrition 0.000 description 2
- 239000003120 macrolide antibiotic agent Substances 0.000 description 2
- 235000019629 palatability Nutrition 0.000 description 2
- 241000192125 Firmicutes Species 0.000 description 1
- 241000287828 Gallus gallus Species 0.000 description 1
- IEMDOFXTVAPVLX-YWQHLDGFSA-N Leucomycin A1 Chemical compound CO[C@H]1[C@H](O)CC(=O)O[C@H](C)C\C=C\C=C\[C@H](O)[C@H](C)C[C@H](CC=O)[C@@H]1O[C@H]1[C@H](O)[C@@H](N(C)C)[C@H](O[C@@H]2O[C@@H](C)[C@H](OC(=O)CC(C)C)[C@](C)(O)C2)[C@@H](C)O1 IEMDOFXTVAPVLX-YWQHLDGFSA-N 0.000 description 1
- 241000204031 Mycoplasma Species 0.000 description 1
- 206010028813 Nausea Diseases 0.000 description 1
- 241000606701 Rickettsia Species 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 239000004480 active ingredient Substances 0.000 description 1
- 239000003674 animal food additive Substances 0.000 description 1
- 230000001458 anti-acid effect Effects 0.000 description 1
- 230000015556 catabolic process Effects 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 230000002950 deficient Effects 0.000 description 1
- 238000006731 degradation reaction Methods 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- 230000002496 gastric effect Effects 0.000 description 1
- 229940041033 macrolides Drugs 0.000 description 1
- 230000008693 nausea Effects 0.000 description 1
- 244000052769 pathogen Species 0.000 description 1
- 230000001717 pathogenic effect Effects 0.000 description 1
- 239000006187 pill Substances 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 230000000241 respiratory effect Effects 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 239000000273 veterinary drug Substances 0.000 description 1
- 230000008673 vomiting Effects 0.000 description 1
Images
Landscapes
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Description
Claims (4)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN2009101814186A CN101611766B (en) | 2009-07-16 | 2009-07-16 | Production method of enteric-coated kitasamycin for feed |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN2009101814186A CN101611766B (en) | 2009-07-16 | 2009-07-16 | Production method of enteric-coated kitasamycin for feed |
Publications (2)
Publication Number | Publication Date |
---|---|
CN101611766A true CN101611766A (en) | 2009-12-30 |
CN101611766B CN101611766B (en) | 2012-06-06 |
Family
ID=41491806
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN2009101814186A Expired - Fee Related CN101611766B (en) | 2009-07-16 | 2009-07-16 | Production method of enteric-coated kitasamycin for feed |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN101611766B (en) |
Cited By (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN104686808A (en) * | 2015-03-26 | 2015-06-10 | 无锡正大畜禽有限公司 | 50% enteric package zinc oxide nanoparticle preparation method |
CN104938791A (en) * | 2015-06-11 | 2015-09-30 | 深圳市裕农科技股份有限公司 | Fodder baking soda stomach-pass sustained-release agent and preparation method thereof |
CN105534950A (en) * | 2016-01-05 | 2016-05-04 | 无锡华诺威动物保健品有限公司 | Production method for kitasamycin solid micro-capsules for feed |
CN106260599A (en) * | 2016-08-12 | 2017-01-04 | 广汉隆达饲料有限公司 | Enteric zinc oxide micropill |
CN106265595A (en) * | 2016-09-29 | 2017-01-04 | 甘肃瑞和祥生物科技有限公司 | A kind of enteric kitasamycin sustained-release micro-spheres and preparation method thereof |
CN107518175A (en) * | 2016-06-29 | 2017-12-29 | 湖南晶天科技实业有限公司 | A kind of feed addictive coating aliphatic acid copper and preparation method thereof and a kind of feed |
CN108902476A (en) * | 2018-07-26 | 2018-11-30 | 湖南普菲克生物科技有限公司 | A kind of sustained release sodium butyrate and preparation method thereof suitable for different livestock and poultry |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN100431515C (en) * | 2005-05-24 | 2008-11-12 | 浙江大学 | Method for preparing additive of stable micronized medication |
CN101045064A (en) * | 2007-01-30 | 2007-10-03 | 佛山市海纳川药业有限公司 | Gitamycin slow-release micro-ball preparation and its preparing process |
-
2009
- 2009-07-16 CN CN2009101814186A patent/CN101611766B/en not_active Expired - Fee Related
Cited By (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN104686808A (en) * | 2015-03-26 | 2015-06-10 | 无锡正大畜禽有限公司 | 50% enteric package zinc oxide nanoparticle preparation method |
CN104938791A (en) * | 2015-06-11 | 2015-09-30 | 深圳市裕农科技股份有限公司 | Fodder baking soda stomach-pass sustained-release agent and preparation method thereof |
CN104938791B (en) * | 2015-06-11 | 2018-03-13 | 深圳市裕农科技股份有限公司 | Sodium bicarbonate stomach-passing sustained-release agent for feed and preparation method thereof |
CN105534950A (en) * | 2016-01-05 | 2016-05-04 | 无锡华诺威动物保健品有限公司 | Production method for kitasamycin solid micro-capsules for feed |
CN107518175A (en) * | 2016-06-29 | 2017-12-29 | 湖南晶天科技实业有限公司 | A kind of feed addictive coating aliphatic acid copper and preparation method thereof and a kind of feed |
CN106260599A (en) * | 2016-08-12 | 2017-01-04 | 广汉隆达饲料有限公司 | Enteric zinc oxide micropill |
CN106265595A (en) * | 2016-09-29 | 2017-01-04 | 甘肃瑞和祥生物科技有限公司 | A kind of enteric kitasamycin sustained-release micro-spheres and preparation method thereof |
CN108902476A (en) * | 2018-07-26 | 2018-11-30 | 湖南普菲克生物科技有限公司 | A kind of sustained release sodium butyrate and preparation method thereof suitable for different livestock and poultry |
Also Published As
Publication number | Publication date |
---|---|
CN101611766B (en) | 2012-06-06 |
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Legal Events
Date | Code | Title | Description |
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C06 | Publication | ||
PB01 | Publication | ||
C10 | Entry into substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
C14 | Grant of patent or utility model | ||
GR01 | Patent grant | ||
C53 | Correction of patent of invention or patent application | ||
CB03 | Change of inventor or designer information |
Inventor after: Zhou Ling Inventor after: Ye Fengxian Inventor after: Feng Jingbo Inventor before: Zhou Ling Inventor before: Ye Fengxian |
|
COR | Change of bibliographic data |
Free format text: CORRECT: INVENTOR; FROM: ZHOU LING YE FENGXIAN TO: ZHOU LING YE FENGXIAN FENG JINGBO |
|
C56 | Change in the name or address of the patentee | ||
CP01 | Change in the name or title of a patent holder |
Address after: Wuxi new Mei Cun Qun Xing Lu 214112 Jiangsu city of Wuxi province No. 51 Patentee after: WUXI ZHENGDA BIOLOGY Co.,Ltd. Address before: Wuxi new Mei Cun Qun Xing Lu 214112 Jiangsu city of Wuxi province No. 51 Patentee before: WUXI ZHENGDA POULTRY Co.,Ltd. |
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CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20120606 |
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CF01 | Termination of patent right due to non-payment of annual fee |