CN101596270B - Medicine for treating chronic pharyngitis and preparation method thereof - Google Patents

Medicine for treating chronic pharyngitis and preparation method thereof Download PDF

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Publication number
CN101596270B
CN101596270B CN2009100748030A CN200910074803A CN101596270B CN 101596270 B CN101596270 B CN 101596270B CN 2009100748030 A CN2009100748030 A CN 2009100748030A CN 200910074803 A CN200910074803 A CN 200910074803A CN 101596270 B CN101596270 B CN 101596270B
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radix
medicine
chronic pharyngitis
treatment
root
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CN101596270A (en
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李春荣
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Abstract

The invention relates to a medicine for treating chronic pharyngitis. Tree peony bark, red paeony root, liquorice, rhubarb, subprostrate sophora, stiff silkworm, rhizoma bolbostemmae, pollen, angelica, root of rehmannia, peach kernel, safflower, achyranthes, sichuan lavage rhizome, balloonflower root, belamcanda sinensis and radix scrophulariae are added with water and poached twice, the decoctions are merged and concentrated to extract with relative density of 1.04-1.05 at 50 DEG C, the extract is dried and then crushed into fine powder to be encapsulated, thus obtaining capsules. The medicine of the invention has the efficacies of cleaning away heat and toxic material, soothing the liver to relieve upset, promoting the production of body fluid and relieving thirst and regulating qi-flowing for relieving pain and can treat both manifestation and root cause of chronic pharyngitis with obvious curative effect; and the total effect through clinical observation is 83.3%.

Description

A kind of medicine that is used for the treatment of chronic pharyngitis and preparation method thereof
Technical field
The present invention relates to a kind of medicine for the treatment of chronic pharyngitis, particularly relating to a kind of is the medicine of the treatment chronic pharyngitis of crude drug preparation with Chinese medicine.The invention still further relates to the preparation method of this medicine.
Background technology
Chronic pharyngitis is that pharyngeal mucosa, mucosa reach adenoid diffuse inflammation down, clinically with dry laryngopharynx, the pain of itching is uncomfortable, blocks if any foreign body, and that tells does not go out, not descending of pharynx, the few expectorant of dry cough is symptom, the no significant organic pathological changes of having a medical check-up, and the course of disease is touching, bad during state of an illness fashion, symptom is outbreak repeatedly easily.
Doctor trained in Western medicine thinks that chronic pharyngitis is the outbreak repeatedly by acute pharyngitis, the upper respiratory tract chronic inflammatory disease stimulates, stimulations such as tobacco and wine are excessive, dust, harmful gas, happiness food irritable food, occupational factor and physical factors, systemic factors such as anemia, dyspepsia, heart disease, chronic bronchitis, endocrine regulation cause that Therapeutic Method mainly is the antibiotic or anti-inflammatory drug of topical application.But its Therapeutic Method curative effect is all not remarkable, and effect only can reach the effect of mitigation symptoms, can not treating both the principal and secondary aspects of a disease.
The Chinese medicine determination of treatment based on pathogenesis obtained through differentiation of symptoms and signs is evident in efficacy, can treating both the principal and secondary aspects of a disease.Therefore, the Chinese medicine preparation of exploitation determination of treatment based on pathogenesis obtained through differentiation of symptoms and signs has the important clinical meaning to the treatment of chronic pharyngitis.
Summary of the invention
Purpose of the present invention just provides a kind of medicine for the treatment of chronic pharyngitis, with treating both the principal and secondary aspects of a disease, improves the therapeutic effect of chronic pharyngitis.
Medicine of the present invention is that crude drug prepares by following parts by weight of traditional Chinese medicines:
Cortex Moutan 10~15 Radix Paeoniae Rubra 12~18
Radix Glycyrrhizae 4~8 Radix Et Rhizoma Rhei 2~6
Radix Sophorae Tonkinensis 8~12 Bombyx Batryticatus 12~18
Bulbus Fritillariae Thunbergii 10~15 pollen 12~18
Radix Angelicae Sinensis 10~15 Radix Rehmanniae 6~10
Semen Persicae 8~15 Flos Carthamis 8~12
Radix Achyranthis Bidentatae 12~18 Rhizoma Chuanxiongs 12~18
Radix Platycodonis 8~15 Rhizoma Belamcandae 8~12
Radix Scrophulariae 10~15.
Said medicine can be made any dosage form on the pharmaceutics, as tablet, pill, powder, capsule etc., the preferred dosage form of the present invention is a capsule.
The concrete preparation method of above-mentioned each component being made medicine of the present invention may further comprise the steps:
Said medicine according to described parts by weight mix homogeneously, is decocted with water 2 times, each 4h, collecting decoction filters, and is condensed into the clear paste of 50 ℃ of relative densities 1.04~1.05, and drying is ground into fine powder, makes capsule in incapsulating.
The traditional Chinese medical science thinks that chronic pharyngitis belongs to motherland's medical science " globus hystericus ", also claims " stagnation of QI time " category, and it takes place with feelings will factor obvious relation is arranged, and belongs to due to the scorching wind and cold of wind heat residual poison more.The suitable heat-clearing and toxic substances removing of treatment, dissipating phlegm and resolving masses, promoting the production of body fluid to quench thirst, regulating QI to relieve pain.In the prescription of the present invention, Cortex Moutan clearing away heat and cooling blood, blood circulation promoting and blood stasis dispelling; The Radix Paeoniae Rubra clearing away heat and cooling blood, eliminating stasis to stop pain; The Radix Glycyrrhizae heat-clearing and toxic substances removing, with coordinating the actions of various ingredients in a prescription; Radix Et Rhizoma Rhei purging heat and dredging bowels, removing pathogenic heat from blood and toxic substance from the body, eliminating blood stasis and inducing menstruation; Radix Sophorae Tonkinensis relieves inflammation or internal heat, detoxifies, detumescence, pain relieving; The Bombyx Batryticatus detoxicating and resolving stagnation of pathogens; The Bulbus Fritillariae Thunbergii heat-clearing and toxic substances removing; Pollen clearing away heat and promoting production of body fluid, detumescence and apocenosis; Chinese angelica blood supplementing is invigorated blood circulation, menstruction regulating and pain relieving, loosening bowel to relieve constipation; Radix Rehmanniae clearing away heat and cooling blood, YIN nourishing and the production of body fluid promoting; Semen Persicae, Flos Carthami blood circulation promoting and blood stasis dispelling, loosening bowel to relieve constipation; Radix Achyranthis Bidentatae dissipating blood stasis blood, subduing inflammation, invigorating the liver and kidney, bone and muscle strengthening; Rhizoma Chuanxiong blood-activating and qi-promoting, wind-expelling pain-stopping; Radix Platycodonis dispelling phlegm and relieving sore-throat, evacuation of pus; Rhizoma Belamcandae heat-clearing and toxic substances removing, throat, expectorant saliva; Radix Scrophulariae clearing away heat and cooling blood, replenishing YIN and removing heat, eliminating fire and detoxication, hard masses softening and resolving.All medicines share, and have the effect of heat-clearing and toxic substances removing, dispersing the stagnated live-QI to relieve the stagnation of QI, promoting the production of body fluid to quench thirst, regulating QI to relieve pain, and treatment chronic pharyngitis treating both the principal and secondary aspects of a disease is evident in efficacy.
Drug use of the present invention is convenient, and the patient is easy to take, and takes safety, can reduce complication and take place, and price is suitable.
For further investigating the clinical efficacy and the safety of medicine of the present invention, select 90 routine chronic pharyngitis patients that the curative effect of medicine of the present invention is carried out clinical observation.
Among the 90 routine patients, male 24 examples, women 66 examples; At 18~65 years old age, person's 57 examples account for 13.3% more than 40 years old.Diagnostic symptom is a foreign body sensation in the throat, and follows other symptoms such as pharyngodynia with dryness, the stifled sense of expanding, and empty pharynx does not obviously influence and swallows, and is relevant with Nervous and Mental Factors.All the patient gets rid of organic disease through the training inspection, is diagnosed as chronic pharyngitis.
The oral medicine of the present invention of Therapeutic Method, each 2, every day 2 times.
Criterion of therapeutical effect recovery from illness: cardinal symptom and follow disease disappearance.Effectively: cardinal symptom disappears substantially, and simultaneous phenomenon does not disappear entirely.Invalid: 2 all symptoms course of treatment persons as before take medicine.
Through 6~10 days treatment, 90 routine chronic pharyngitis patients, 47 examples of fully recovering, effective 28 examples account for 52.2% and 31.1% respectively, and total effective rate reaches 83.3%.
The specific embodiment
Embodiment 1
Cortex Moutan 10g, Radix Paeoniae Rubra 12g, Radix Glycyrrhizae 4g, Radix Et Rhizoma Rhei 2g, Radix Sophorae Tonkinensis 8g, Bombyx Batryticatus 12g, Bulbus Fritillariae Thunbergii 10g, pollen 12g, Radix Angelicae Sinensis 10g, Radix Rehmanniae 6g, Semen Persicae 8g, Flos Carthami 8g, Radix Achyranthis Bidentatae 12g, Rhizoma Chuanxiong 12g, Radix Platycodonis 8g, Rhizoma Belamcandae 8g, Radix Scrophulariae 10g, after choosing most impurity, screening dry in the sun, oven dry, place extraction pot, add water to and flood medicine just, decoct 4h, filter, the decocting that adds same amount again boils 4h, collecting decoction, be concentrated into the clear paste of 50 ℃ of relative densities 1.05, drying is ground into fine powder, makes capsule in incapsulating.
Embodiment 2
Cortex Moutan 15g, Radix Paeoniae Rubra 18g, Radix Glycyrrhizae 8g, Radix Et Rhizoma Rhei 6g, Radix Sophorae Tonkinensis 12g, Bombyx Batryticatus 18g, Bulbus Fritillariae Thunbergii 15g, pollen 18g, Radix Angelicae Sinensis 15g, Radix Rehmanniae 10g, Semen Persicae 15g, Flos Carthami 12g, Radix Achyranthis Bidentatae 18g, Rhizoma Chuanxiong 18g, Radix Platycodonis 15g, Rhizoma Belamcandae 12g, Radix Scrophulariae 15g, choose most impurity, the screening dry in the sun, the oven dry be placed in the extraction pot, add water to and flood medicine just, decoct 4h, filter, the decocting that adds same amount again boils 4h, collecting decoction, be concentrated into the clear paste of 50 ℃ of relative densities 1.05, dry, be ground into fine powder, make capsule in incapsulating.

Claims (3)

1. medicine that is used for the treatment of chronic pharyngitis is to be that crude drug prepares by following parts by weight of traditional Chinese medicines:
Cortex Moutan 10~15 Radix Paeoniae Rubra 12~18
Radix Glycyrrhizae 4~8 Radix Et Rhizoma Rhei 2~6
Radix Sophorae Tonkinensis 8~12 Bombyx Batryticatus 12~18
Bulbus Fritillariae Thunbergii 10~15 pollen 12~18
Radix Angelicae Sinensis 10~15 Radix Rehmanniae 6~10
Semen Persicae 8~15 Flos Carthamis 8~12
Radix Achyranthis Bidentatae 12~18 Rhizoma Chuanxiongs 12~18
Radix Platycodonis 8~15 Rhizoma Belamcandae 8~12
Radix Scrophulariae 10~15.
2. the medicine that is used for the treatment of chronic pharyngitis according to claim 1 is characterized in that described medicine is made capsule.
3. the described preparation method that is used for the treatment of the medicine of chronic pharyngitis of claim 2, be according to described parts by weight mix homogeneously with said medicine, decoct with water 2 times, each 4h, collecting decoction filters, be condensed into the clear paste of 50 ℃ of relative densities 1.04~1.05, drying is ground into fine powder, makes capsule in incapsulating.
CN2009100748030A 2009-07-01 2009-07-01 Medicine for treating chronic pharyngitis and preparation method thereof Expired - Fee Related CN101596270B (en)

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Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102670949B (en) * 2012-05-18 2013-11-13 宋协勘 Traditional Chinese medicine for treating chronic laryngitis
CN103495021B (en) * 2013-10-16 2015-07-15 刘运波 Traditional Chinese medicine for treating chronic pharyngitis
CN104224982A (en) * 2014-08-28 2014-12-24 谢菲 Traditional Chinese medicine powder preparation for treating chronic pharyngitis

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1621082A (en) * 2003-11-26 2005-06-01 岐黄药业科技投资有限责任公司 Chinese traditional medicinal composition for treating acne
CN1682991A (en) * 2005-02-23 2005-10-19 广东怡康制药有限公司 Chinese medicine composition for treating dermatosis and its preparing method
CN1899535A (en) * 2006-06-28 2007-01-24 广东皮宝制药有限公司 Method for preparing dermopathic blood toxic capsule

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1621082A (en) * 2003-11-26 2005-06-01 岐黄药业科技投资有限责任公司 Chinese traditional medicinal composition for treating acne
CN1682991A (en) * 2005-02-23 2005-10-19 广东怡康制药有限公司 Chinese medicine composition for treating dermatosis and its preparing method
CN1899535A (en) * 2006-06-28 2007-01-24 广东皮宝制药有限公司 Method for preparing dermopathic blood toxic capsule

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