CN101550142B - Preparation method of ulifloxacin optical isomer - Google Patents
Preparation method of ulifloxacin optical isomer Download PDFInfo
- Publication number
- CN101550142B CN101550142B CN2008100272123A CN200810027212A CN101550142B CN 101550142 B CN101550142 B CN 101550142B CN 2008100272123 A CN2008100272123 A CN 2008100272123A CN 200810027212 A CN200810027212 A CN 200810027212A CN 101550142 B CN101550142 B CN 101550142B
- Authority
- CN
- China
- Prior art keywords
- ulifloxacin
- dimethyl sulfoxide
- lisha star
- preparation
- optical isomer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
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- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Abstract
Description
Claims (1)
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN2008100272123A CN101550142B (en) | 2008-04-03 | 2008-04-03 | Preparation method of ulifloxacin optical isomer |
PCT/CN2009/071137 WO2009121304A1 (en) | 2008-04-03 | 2009-04-02 | Preparation of ulifloxacin optical isomer |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN2008100272123A CN101550142B (en) | 2008-04-03 | 2008-04-03 | Preparation method of ulifloxacin optical isomer |
Publications (2)
Publication Number | Publication Date |
---|---|
CN101550142A CN101550142A (en) | 2009-10-07 |
CN101550142B true CN101550142B (en) | 2011-04-27 |
Family
ID=41134851
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN2008100272123A Active CN101550142B (en) | 2008-04-03 | 2008-04-03 | Preparation method of ulifloxacin optical isomer |
Country Status (2)
Country | Link |
---|---|
CN (1) | CN101550142B (en) |
WO (1) | WO2009121304A1 (en) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101768172B (en) | 2010-01-13 | 2012-04-18 | 海南皇隆制药股份有限公司 | Optical active compound of anti-infective prulifloxacin and preparation method thereof |
CN102198134B (en) * | 2010-03-22 | 2013-06-26 | 北京联木医药技术发展有限公司 | Use of new stable Ulifloxacin hydrochloride in preparation of anti-infection medicine |
CN102424688B (en) * | 2011-12-31 | 2014-08-20 | 广州医药工业研究院 | Levoulifloxacin mesylate crystal, its preparation method and application |
CN102424689B (en) * | 2011-12-31 | 2014-05-28 | 广州医药工业研究院 | Levo ulifloxacin mesylate crystal as well as preparation method and application thereof |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2536678B2 (en) * | 1989-11-17 | 1996-09-18 | 日本新薬株式会社 | Optically active quinolinecarboxylic acid derivative |
-
2008
- 2008-04-03 CN CN2008100272123A patent/CN101550142B/en active Active
-
2009
- 2009-04-02 WO PCT/CN2009/071137 patent/WO2009121304A1/en active Application Filing
Non-Patent Citations (4)
Title |
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JP平3-218383A 1991.09.25 |
Jun Segawa et al.Studies on pyridonecarboxylic acids. IV. Synthesis and antibacterial activity evaluation of S-(-)- and R-(+)-6-fluoro-1-methyl-4-oxo-7-(1-piperazinyl)-4H-[1,3]thiazeto[3,2-a]quinoline-3-carboxylic acids.《Chemical & Pharmaceutical Bulletin》.1995,第43卷(第7期),第1238-1240页. |
Jun Segawa et al.Studies on pyridonecarboxylic acids. IV. Synthesis and antibacterial activity evaluation of S-(-)-and R-(+)-6-fluoro-1-methyl-4-oxo-7-(1-piperazinyl)-4H-[1,3]thiazeto[3,2-a]quinoline-3-carboxylic acids.《Chemical & * |
Pharmaceutical Bulletin》.1995,第43卷(第7期),第1238-1240页. * |
Also Published As
Publication number | Publication date |
---|---|
CN101550142A (en) | 2009-10-07 |
WO2009121304A1 (en) | 2009-10-08 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
C06 | Publication | ||
PB01 | Publication | ||
C10 | Entry into substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
C14 | Grant of patent or utility model | ||
GR01 | Patent grant | ||
CI01 | Publication of corrected invention patent application |
Correction item: Patentee Correct: Guangzhou Pharmaceutical Industry Research Institute|510240. No. 134, Jiangnan Road, Guangzhou, Guangdong, Haizhuqu District|Baiyunshan Pharmaceutical General Factory, Baiyunshan Pharmaceutical Co., Ltd, G False: Guangzhou Pharmaceutical Industry Research Institute|510240. No. 134, Jiangnan Road, Guangzhou, Guangdong, Haizhuqu District|Baiyunshan Pharmaceutical General Factory, Baiyunshan Pharmaceutical Co., Ltd, G Number: 17 Volume: 27 |
|
C56 | Change in the name or address of the patentee | ||
CP01 | Change in the name or title of a patent holder |
Address after: 510240 Haizhuqu District Jiangnan Road, Guangdong, No. 134, No. Patentee after: GUANGZHOU GENERAL PHARMACEUTICAL RESEARCH INSTITUTE Co.,Ltd. Patentee after: GUANGZHOU BAIYUNSHAN PHARMACEUTICAL HOLDINGS Co.,Ltd. BAIYUNSHAN PHARMACEUTICAL GENERAL FACTORY Address before: 510240 Haizhuqu District Jiangnan Road, Guangdong, No. 134, No. Patentee before: Guangzhou General Pharmaceutical Research Institute Patentee before: GUANGZHOU BAIYUNSHAN PHARMACEUTICAL HOLDINGS Co.,Ltd. BAIYUNSHAN PHARMACEUTICAL GENERAL FACTORY Address after: 510240 Haizhuqu District Jiangnan Road, Guangdong, No. 134, No. Patentee after: GUANGZHOU GENERAL PHARMACEUTICAL Research Institute Patentee after: GUANGZHOU BAIYUNSHAN PHARMACEUTICAL HOLDINGS Co.,Ltd. BAIYUNSHAN PHARMACEUTICAL GENERAL FACTORY Address before: 510240 Haizhuqu District Jiangnan Road, Guangdong, No. 134, No. Patentee before: GUANGZHOU INSTITUTE OF PHARMACEUTICAL INDUSTRY Patentee before: GUANGZHOU BAIYUNSHAN PHARMACEUTICAL Co.,Ltd. GUANGZHOU BAIYUNSHAN PHARMACEUTICAL FACTORY |