CN101537228B - Transcranial magnetic therapeutic instrument for computer diseases - Google Patents
Transcranial magnetic therapeutic instrument for computer diseases Download PDFInfo
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- CN101537228B CN101537228B CN200910071875XA CN200910071875A CN101537228B CN 101537228 B CN101537228 B CN 101537228B CN 200910071875X A CN200910071875X A CN 200910071875XA CN 200910071875 A CN200910071875 A CN 200910071875A CN 101537228 B CN101537228 B CN 101537228B
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Abstract
The invention provides a transcranial magnetic therapeutic instrument for computer diseases, comprising a field effect cap which can be worn on head, field effect cap internally being distributed with electrodes and at least one electromagnet; the instrument further comprises an electroencephalographic simulative generator, and the electroencephalographic simulative generator is respectively connected with the electromagnet and the electrodes via conducting wires. In the invention, nerve cell nucleus of intracephalic basal ganglia part can be self-excited by a stereoscopic superposition alternating magnetic field transcranially magnetically formed at intracephalic deep part and a weak induced current formed at a specific part of intracephalic deep part; and the transcranial magnetic effect is strengthened when the nerve cell nucleus transcranially pass through basal ganglia part. The invention is not an interventional therapy but can achieve the functions of stimulating and recovering neurotransmitters of nerve cell nucleus of intracephalic basal ganglia part such as autocrine dopamine, and is applied to encephalopathic therapy such as Parkinson, encephalatrophy, epileptics and gork; the effects exceed that of a brain pacemaker, thereby overcoming the disadvantages of pharmacotherapy and surgical therapy; and the therapeutic instrument can be used in hospital, and is more applied to treatment of patients at home.
Description
(1) technical field
What the present invention relates to is a kind of medical equipment, specifically a kind of therapeutic equipments of preventing and treating encephalopathys such as parkinson, brain atrophy, epileptics, plant man.
(2) background technology
Parkinson disease (Parkinson ' s disease) are claimed " Parkinsonism " again; It is a kind of central nervous system degenerative disease; Mainly be because of after the cell generation pathologic change that is arranged in midbrain position " black substance "; The synthetic minimizing of dopamine, the function that suppresses acetylcholine reduces, and then the excitation of acetylcholine strengthens relatively." Parkinsonism " just appearred in the result that both are unbalance.This sick age of onset is the most common with 50 to 79 years old, shows according to external statistical data, approximately just has a people to suffer from parkinson disease in the middle of per 800 people.
The Parkinsonian method of general treatment all is to come disease controlling with the medicine dopamine, but the result of long-term prescription can make in the brain and can synthesize and secrete the position deterioration of dopamine naturally, and then brings more side effect and complication.Pharmacotherapy can not fundamentally stop the organic growth of primary disease, and along with the increase of drug dose, curative effect worse and worse.
But along with medical science is constantly progressive, more serious to some late periods or the state of an illness, and the state of an illness that medicine can't effectively be controlled just need be had an operation.Parkinsonian operation method is main at present to divide three types.
The first kind: nerve nucleus is damaged art, like thalamus, pallidotomy etc.
Second type: brain deep electrostimulation (DBS), popular in developed country with the area, replaced the damage art basically.
The 3rd type: the histiocyte transplantation, utilize horseley-Clarke technique can produce the neurocyte of dopamine, like tire brain or NSC to intracerebral transplantation.
Wherein, the techniques make use electric current of brain deep electrostimulation (DBS) continues to stimulate the target area on brain both sides, suppresses through this zone being caused the not normal signal conduction of motor function.At first the doctor can implant corpus hypothalamicum (STN) in the brain with the lead of a strip electrode, and when the patient was clear-headed, the doctor can come the therapeutic effect of test patient with electricity irritation, and for example muscle ossify or whether jitter alleviates.As satisfactory for result, the doctor can reserve the placement location of electrode, and is fixed on the skull, and patient is anaesthetized sb. generally, and it is connected near the nerve stimulator of planting clavicle by the extended line under the scalp.
The patient can adjust the degree of electricity irritation according to the degree of own limbs shake, symptoms such as that the patient that brain pacemaker is installed can improve usually is stiff, tremble, instability of gait, and can alleviate and take the trick unusual fluctuation that medicine produces.Dosage can reduce by 50% to general patient in the operation back, and mobility then on average improves 50% to 60%.The DBS technology has its characteristics than operation method in the past.
At first, DBS is reversible and adjustable.Nerve nucleus is not damaged in operation, just makes it temporarily be in electric palsy, improves function of nervous system, and the degree of nerve nucleus paralysis, scope can be regulated through a plurality of factors such as electric current, voltage, frequency and electrode position of setting the brain depth electrode.In the very long date after surgery, also can constantly regulate parkinson disease symptom that can the continuous development and change of long-term control with change of illness state.
Secondly, DBS can experience.Behind the operation implant electrode, can the time of several days adaptation, experience and observation being arranged for patient and family members, determine the operation plan that final sum is best again through the interim method that stimulates.Reduce operation in the past because factors such as patient's anxiety cause curative effect to judge inaccurate phenomenon.
Once more, DBS is developable.Operation keeps the function of nervous system of normal cerebral tissue, for the new method that possibly occur later on creates conditions, has also just kept the patient and has obtained newborn right and hope.
At last, DBS is a bilateral.Parkinsonian's bilateral all can be affected, but damages bilateral pallidum or thalamus, occurs severe complications easily.Side effect then seldom appears in DBS, and this is the major reason that patient takes like a shot.
Just owing to above-mentioned advantage, in developed countries such as the U.S., Canada and Europe, the few have done the damage art, and the Parkinsonian who accepts the brain pacemaker treatment is more and more, at home, has also treated considerable case.
Place the deficiency of brain pacemaker, mainly contain following some:
1, expense is high.Surgery cost is very expensive, also wants more than 10 ten thousand yuan with home-made brain pacemaker, import want more than 20 ten thousand yuan.
2, operation back patient can not " break away from service area ".The doctor must carry out follow-up study to the patient, helps to solve the uncomfortable problem of using.
3, neither put things right once and for all behind the placement brain pacemaker, but the degenerative factor causes because most parkinson disease all are, concerning the patient, As time goes on and one by one the state of an illness increases the weight of is inevitable.Therefore, usually operation back 5 to 8 years will updating device, changes battery.
(3) summary of the invention
The object of the present invention is to provide a kind of shortcoming that can overcome Drug therapy and operative treatment; Easy to operate, cost is low; Not only can use, be more suitable for the patient and treat in the family, to preventing and treating the tangible transcranial magnetic therapeutic instrument for computer diseases of brain diseases effect such as parkinson in hospital.
The objective of the invention is to realize like this:
It comprises can be with the field effect medicated cap at head, and field effect medicated cap inside is distributed with electrode and at least one electric magnet, and it also comprises brain electrical analogue generator, and electric magnet links to each other with brain electrical analogue generator respectively through lead with electrode.
The present invention can also comprise some architectural features like this:
1, described electric magnet is 1-8, and each electric magnet connects the back in parallel and links to each other with brain electrical analogue generator.
2, described electrode is at least one pair of; The both positive and negative polarity of every counter electrode is installed in the field effect medicated cap; Positive and negative electrode is symmetrically distributed in the same plane Z, and the characteristic of plane Z is that directly to go up in the 6cm 2 line with the ears have sharp ears be axle, and planar angle is that the front end minimum point is to Yintang acupoint.
3, described electrode comprises positive pole and negative pole, and positive pole is installed in the field effect medicated cap, and negative pole is installed in the wrist strap.
4, described field effect medicated cap inside is equipped with guide rail, and the balladeur train that can on guide rail, move or lock is installed on the guide rail, and electric magnet and electrode are installed on the balladeur train separately.
5, in field effect medicated cap inside at least one block permanent magnet is installed also.
6, it also comprises self-adhering electrode, and self-adhering electrode links to each other with brain electrical analogue generator through lead.
7, it also comprises a pair of ear electrode, and a pair of ear electrode links to each other with brain electrical analogue generator through lead.
8, described brain electrical analogue generator by housing, be installed on and off switch on the housing, dilatational wave accessory power outlet, square wave accessory power outlet, impulse waveform permutator, field effect medicated cap accessory power outlet, magnetic field intensity selector switch, pulse current functional indicator light, pulse current intensity display lamp and treatment signal generating circuit and constitute; Said treatment signal generating circuit is made up of DC power supply circuit, timing sounding electric circuit, pulse signal generation circuit, dilatational wave output circuit, square wave output circuit, booster circuit, display circuit, field signal generation circuit; The output termination of said DC power supply circuit connects a regularly input of sounding electric circuit, pulse signal generation circuit, square wave output circuit, booster circuit, display circuit; Another input of an output termination booster circuit of pulse signal generation circuit; The outfan of booster circuit connects an input of dilatational wave output circuit and square wave output circuit respectively through the impulse waveform permutator; Two outfans of pulse signal generation circuit connect two inputs of dilatational wave output circuit respectively; The dilatational wave output circuit carries out this two-way dilatational wave signal to export through the contact pin of dilatational wave accessory power outlet and field effect medicated cap accessory power outlet after the power amplification; The dilatational wave accessory power outlet connects a pair of self-adhering electrode through plug and lead; The contact pin of field effect medicated cap accessory power outlet connects the electrode in the field effect medicated cap through plug and lead; An input of an output termination square wave output circuit of pulse signal generation circuit, the square wave output circuit carries out this square-wave signal to export through the square wave accessory power outlet after the power amplification, and the square wave accessory power outlet connects a pair of ear electrode through plug and lead; An input of the output termination display circuit of booster circuit; Two inputs of two output termination display circuits of pulse signal generation circuit, an output termination of pulse signal generation circuit is the input of sounding electric circuit regularly, the input of the output termination field signal generation circuit of DC power supply circuit; The outfan of field signal generation circuit is through the contact pin output of field effect medicated cap accessory power outlet, and the contact pin of field effect medicated cap accessory power outlet connects the electric magnet in the field effect medicated cap through plug and lead.
Compared with techniques with brain deep electrostimulation (DBS); Transcranial magnetic therapeutic instrument for computer diseases of the present invention; Form three-dimensional stack alternating magnetic field in the brain deep through electric magnet, and draw faradic current, faradic intensity is near the brain pacemaker intensity that corresponding site produced in brain; The electric current that electrode produced through being symmetrically distributed can pass through brain " black substance " position, and the reinforcing stimulus effect is played at this position, can reach the function that stimulates and recover neurotransmitteies such as Basal ganglia position, brain deep neurocyte nuclear colony autocrine dopamine.Use transcranial magnetic therapeutic instrument for computer diseases, can accomplish not to be in hospital, do not perform the operation; Stay out of, even can withdraw medicine, just can meet or exceed the effect that brain deep electrostimulation is produced; Medical expense can be reduced in 10,000 yuan simultaneously, is a kind of pure green family cure instrument for encephalic diseases.Parkinson are not only treated in this invention, equally brain atrophy, epileptics, plant are had significant curative effect per capita.
The present invention is to provide a kind of transcranial magnetic therapeutic instrument for computer diseases.It comprises the field effect medicated cap that can be worn over head, and field effect medicated cap inside is distributed with electrode and at least one electric magnet, and it also comprises brain electrical analogue generator, and electric magnet links to each other with brain electrical analogue generator respectively through lead with electrode.The present invention is formed three-dimensional stack alternating magnetic field through cranium magnetic deep in brain, the faint faradic current that specific part is produced in the brain deep, can the self-excitation brain in the neurocyte nuclear colony at Basal ganglia position; When passing through the neurocyte nuclear colony at Basal ganglia position, strengthened effect through the cranium electricity through cranium magnetic.The present invention is non-interventional therapy; Being applicable to the treatment of encephalopathys such as parkinson, brain atrophy, epileptics, plant man, can replacing brain pacemaker---brain deep electrostimulation (DBS), its curative effect have also surmounted DBS; Overcome the shortcoming of Drug therapy and operative treatment; Easy to operate because of it, cost is low, not only can use in hospital, be more suitable for the patient and treat in the family.
The guiding theory of the technical scheme that the present invention provides is: the solid stack alternating magnetic field that produces through the electric magnet that is distributed in around the head and the pulse current combined effect that is distributed in the electrode output around the head are in the brain deep; When disturbing and suppressing unusual brain electricity, the generation of brain magnetic and propagation, directly see through the neurocyte nuclear colony at skull orientation Basal ganglia position in brain, can reach following effect: the function that stimulates and recover neurotransmitteies such as Basal ganglia position, brain deep neurocyte nuclear colony autocrine dopamine; Improve the metabolism environment of brain cell; Quicken the Biochemical processes of brain cell, it is active to change neurotransmitter secretion and enzyme system, improves the content of dopamine in the brain; Increase the recoverability of damaging cells; The diastole cerebrovascular improves blood circulation, promotes the recovery of brain function; Simultaneously, also can eliminate the edema and the swelling of focus surrounding tissue, strengthen fibrinous liquefaction of spot and absorption; Promote the formation of cerebral vasodilators and collateral circulation, alleviate cerebral vasospasm, blood fat reducing and cerebral vascular resistance; Strengthen cerebral blood vessel elasticity; Improve the blood supply and the anaerobic condition of cerebral tissue, improve the metabolism of cerebral tissue, quicken the Biochemical processes of brain cell.Improve the electrical activity of brain cell, secretion of change neurotransmitter and enzyme system are active, and the adjustment autonomic nervous dysfunction promotes the brain metabolism, and the raising cerebral tissue is to the synthetic of material and utilize ability.Can bring out the appearance of alpha rhythm brain wave and increase through resonance, abnormal electroencephalographic wave is reduced, thereby activate the brain cell that is in inhibitory state, promote the ordering of patient's brain electrical acti, make disorderly brain function and nervous system obtain adjustment and recover.
Said field effect medicated cap inside is distributed with a plurality of electrodes and a plurality of electric magnet; Electrode is respectively positive pole and negative pole; Electric magnet connects in parallel; And the alternating magnetic field that utilizes the locus layout of electric magnet in the field effect medicated cap that electric magnet is sent forms three-dimensional stack alternating magnetic field in people's brain ganglion basal zone; Make this zone generation faradic current, magnetic stimulates just as electricity irritation stimulates this regional neurocyte such as black substance when faradic current surpasses nervous tissue's excitement threshold value, plays the effect of the recovery of Biochemical processes, the secretion of change neurotransmitter and the enzyme system activity of quickening brain cell, the content that improves dopamine in the brain, promotion brain function.
It also comprises a pair of self-adhering electrode, and the self-adhering electrode card overlays on the effect that electroacupuncture treatment is played at the relevant acupuncture point of limbs.
It also comprises a pair of ear electrode, and ear's electrode holder is held in by the ear acupuncture point of therapist, and the square wave pulsed current that brain electrical analogue generator is produced acts on the relevant acupuncture point of ear through ear's electrode; Can reflexive stimulation cerebral cortex, promote neural comprehensive recovery, not only can improve health, improve immunity; Strengthen attention; Improving memory and audition, the prevention senile dementia also can play significant rehabilitation effect to various cerebrovascular disease.
The input of the output termination field signal generation circuit of DC power supply circuit; For it provides dc source and the startup through DC power supply circuit controlling magnetic field signal generation function and closes; The outfan of field signal generation circuit is through the contact pin output of field effect medicated cap accessory power outlet; The contact pin of field effect medicated cap accessory power outlet connects the electric magnet in the field effect medicated cap through plug and lead; The alternating current that brain electrical analogue generator is produced forms a three-dimensional stack action of alternating magnetic field in the ganglion basal zone of cerebral tissue through electric magnet; Make this zone produce faradic current; Magnetic stimulates just as electricity irritation stimulates this regional neurocyte such as black substance when faradic current surpasses nervous tissue's excitement threshold value, plays the effect of the recovery of Biochemical processes, the secretion of change neurotransmitter and the enzyme system activity of quickening brain cell, the content that improves dopamine in the brain, promotion brain function.
The scope of application of the present invention is wider, and the technical scheme that the positive pole and the negative pole of electrode is installed in the field effect medicated cap is more suitable in the treatment of diseases such as parkinson; The positive pole of electrode is installed in the field effect medicated cap, and negative pole is installed in the treatment that the interior technical scheme of a wrist strap only is applicable to epileptics.
In described field effect medicated cap inside guide rail is installed, electric magnet and electrode are installed in the technical scheme on the balladeur train separately, can adjust the position of electric magnet, electrode, make it to act on optimum, reach more ideal therapeutic effect.
The present invention is easy to use, safe, promptly suitable family, individual use separately, is adapted at hospital again and promotes.
In order to inquire into transcranial magnetic therapeutic instrument for computer diseases to Parkinsonian clinical efficacy; The Asia-Europe brain science academy in Heilongjiang Province is diagnostic criteria by " diagnosis of parkinsonism and the Differential Diagnosis " that national extrapyramidal disease symposium in 1984 confirms; According to including standard, exclusion standard, rejecting case standard in, select 60 routine disturbances in patients with Parkinson disease to carry out clinical preliminary observation.Wherein 30 examples are organized in treatment, adopt the therapeutic instrument of the present invention treatment that combines with oral madopar tablet; Matched group 30 examples adopt oral madopar to treat.The clinical observation data are following:
1, two groups of curative effects compare (example)
2, the scoring of Webster clinical symptoms changes before and after the treatment group treatment
Annotate: * and preceding relatively P＜0.05 of treatment
Untoward reaction: 2 example headaches, dizzy symptom only appear in the treatment group, and performance is slight, Lock-out after 1～2 day.30 routine patients with hepatic renal functioies, electrocardiogram are all normal, blood pressure and routine blood test all occur unusual.Untoward reaction 12 examples appear in matched group, mainly show as nauseating, dizzy, tired, constipation, vomiting, perspiration, diarrhoea, disappear after 3 days.
Conclusion: above clinical data shows that treatment group curative effect is superior to matched group.This shows that transcranial magnetic therapeutic instrument for computer diseases is having remarkable effect aspect the Parkinsonian treatment.
(4) description of drawings
Fig. 1 is a structural representation of the present invention;
Fig. 2 is the structural representation of field effect medicated cap of the present invention;
Fig. 3 is that electrode belongs to planar localization method sketch map in the field effect medicated cap of the present invention;
Fig. 4 is the theory diagram of brain electrical analogue generator of the present invention;
Fig. 5 is a kind of electrical block diagram of brain electrical analogue generator of the present invention;
Fig. 6 is the structural representation that is used to treat the technical scheme of epileptics.
(5) specific embodiment
For example the present invention is done description in more detail below in conjunction with accompanying drawing:
In conjunction with Fig. 1, the composition of transcranial magnetic therapeutic instrument for computer diseases of the present invention mainly comprises brain electrical analogue generator A and field effect medicated cap B two parts.Can also comprise self-adhering electrode C or the electrode D of ear, also can be also to comprise self-adhering electrode C and the electrode D of ear.
In conjunction with Fig. 2; Field effect medicated cap B inside is distributed with a plurality of electrode p and a plurality of electric magnet y; Electrode p is respectively positive pole and negative pole; Electric magnet y connects in parallel; And the alternating magnetic field that the layout of utilizing electric magnet locus in field effect medicated cap B is sent electric magnet y forms three-dimensional stack alternating magnetic field V in people's brain ganglion basal zone; Make this zone generation faradic current, magnetic stimulates just as electricity irritation stimulates this regional neurocyte such as black substance when faradic current surpasses nervous tissue's excitement threshold value, plays the effect of the recovery of Biochemical processes, the secretion of change neurotransmitter and the enzyme system activity of quickening brain cell, the content that improves dopamine in the brain, promotion brain function.
Like Fig. 1 and shown in Figure 4, brain electrical analogue generator A is by housing e, is installed on and off switch f on the housing, dilatational wave accessory power outlet g, square wave accessory power outlet h, impulse waveform permutator i, field effect medicated cap accessory power outlet j, magnetic field intensity selector switch k, pulse current functional indicator light l, pulse current intensity display lamp m and treatment signal generating circuit n and constitutes.
Like Fig. 4 and shown in Figure 5, treatment signal generating circuit n is made up of DC power supply circuit 1, timing sounding electric circuit 2, pulse signal generation circuit 3, dilatational wave output circuit 4, square wave output circuit 5, booster circuit 6, display circuit 7, field signal generation circuit 8.The output termination of DC power supply circuit 1 is an input of sounding electric circuit 2, pulse signal generation circuit 3, square wave output circuit 5, booster circuit 6, display circuit 7 regularly; Dc source is provided for these circuit; Another input of an output termination booster circuit 6 of pulse signal generation circuit 3; High frequency voltage boosting pulse signal is provided for booster circuit 6; The outfan of booster circuit 6 connects an input of dilatational wave output circuit 4 and square wave output circuit 5 respectively through impulse waveform permutator i, and for dilatational wave output circuit 4 and square wave output circuit 5 provide dc high voltage, two outfans of pulse signal generation circuit 3 connect two inputs of dilatational wave output circuit 4 respectively; For dilatational wave output circuit 4 provides two-way dilatational wave signal; Dilatational wave output circuit 4 carries out this two-way dilatational wave signal to export through j-3, the j-4 contact pin of dilatational wave accessory power outlet g and field effect medicated cap accessory power outlet j after the power amplification, and dilatational wave accessory power outlet g meets a pair of self-adhering electrode C through plug and lead, and self-adhering electrode C card overlays on the effect that electroacupuncture treatment is played at the relevant acupuncture point of limbs; J-3, the j-4 contact pin of field effect medicated cap accessory power outlet j meet the electrode p in the field effect medicated cap through plug and lead; The dilatational wave pulse current that brain electrical analogue generator A is produced acts on cerebral tissue through electrode p, thereby activates the brain cell that is in inhibitory state, adjusts corticocerebral excitement and process of inhibition; Regulate neuro function, the raising cerebral tissue is to the synthetic of material and utilize ability.An input of an output termination square wave output circuit 5 of pulse signal generation circuit 3, for square wave output circuit 5 provides square-wave signal, square wave output circuit 5 carries out this square-wave signal to export through square wave accessory power outlet h after the power amplification; Square wave accessory power outlet h meets a pair of electrode D of ear through plug and lead; The electrode D of ear is clamped in by the ear acupuncture point of therapist, and the square wave pulsed current that brain electrical analogue generator A is produced acts on the relevant acupuncture point of ear through the electrode D of ear, can reflexive stimulation cerebral cortex; Promote neural comprehensive recovery; Not only can improve health, improve immunity, strengthen attention, improving memory and audition; The prevention senile dementia also can play significant rehabilitation effect to various cerebrovascular disease; An input of the output termination display circuit 7 of booster circuit 6; Make display circuit 7 show the Strength Changes of pulse current; Two inputs of two output termination display circuits 7 of pulse signal generation circuit 3 make display circuit 7 show the startup indication of dilatational wave function and square wave function respectively; An output termination of pulse signal generation circuit 3 is the input of sounding electric circuit 2 regularly, for timing sounding electric circuit 2 provides the signal of regularly ringing, uses the people of this instrument to grasp service time.The input of the output termination field signal generation circuit 8 of DC power supply circuit 1; For it provides dc source and the startup through DC power supply circuit 1 controlling magnetic field signal generation function and closes; The outfan of field signal generation circuit 8 is through j-1, the output of j-2 contact pin of field effect medicated cap accessory power outlet j; J-1, the j-2 contact pin of field effect medicated cap accessory power outlet j meet the electric magnet y in the field effect medicated cap through plug and lead; The alternating current that brain electrical analogue generator A is produced acts on the ganglion basal zone of cerebral tissue through three-dimensional stack alternating magnetic field V of the y-shaped one-tenth of electric magnet; Make this zone produce faradic current; Magnetic stimulates just as electricity irritation stimulates this regional neurocyte such as black substance when faradic current surpasses nervous tissue's excitement threshold value, plays the effect of the recovery of Biochemical processes, the secretion of change neurotransmitter and the enzyme system activity of quickening brain cell, the content that improves dopamine in the brain, promotion brain function.
As shown in Figure 5; DC power supply circuit 1 is made up of transformator T1, bridge rectifier Q1, filter capacitor C1 to C4, three-terminal regulator block U2, on and off switch S1; One end of one end protective tube of the primary coil of transformator T1; The other end of the other end of protective tube and transformator T1 meets the termination Z1 and the termination Z2 of 220V alternating current power supply respectively; The secondary coil of transformator T1 has two groups, the foot 3 of one group X1 termination bridge rectifier Q1 wherein, the foot 1 of X2 termination bridge rectifier Q1; The foot 2 of bridge rectifier Q1 connects an end of capacitor C 1, the positive pole of capacitor C 2, the foot 1 of three-terminal regulator block U2; The foot 4 of bridge rectifier Q1 connects the other end of capacitor C 1, the negative pole of capacitor C 2, the foot 2 of three-terminal regulator block U2, the negative pole of capacitor C 3, an end of capacitor C 4, and the foot 3 of three-terminal regulator block U2 connects the positive pole of capacitor C 3, the other end of capacitor C 4, the quiet end of on and off switch S1, the unidirectional current of DC power supply circuit 1 output 6V.
As shown in Figure 5, regularly sounding electric circuit 2 is made up of the foot 2 of the end of a terminating resistor R1 of resistance R 2 and the chip U1 of pulse signal generation circuit 3 buzzer FM1, audion G11, two resistance R 1-R2; Another termination power Vc of resistance R 1, the base stage of another termination audion G11 of resistance R 2, the colelctor electrode of audion G11 connects the end of buzzer FM1; Another termination power Vc of buzzer; The grounded emitter of audion G11 behind the program running certain hour among the chip U1, is exported the high-low level of certain frequencies by the foot 2 of chip U1; Buzzer FM1 just produces ringing of certain frequency, finishes to remind this treatment of user.
As shown in Figure 5; Pulse signal generation circuit 3 is made up of chip U1, four capacitor C 5-C8, resistance R 3, crystal oscillator A7, and the foot 4 of chip U1 connects the end of crystal oscillator A7 and an end of capacitor C 5, and the foot 5 of chip U1 connects the other end of crystal oscillator A7 and an end of capacitor C 6; The other end of capacitor C 5 and capacitor C 6 connects together and ground connection; The foot 19 of chip U1 connects the negative pole of the light emitting diode An of display circuit 7, and the foot 18 of chip U1 connects the negative pole of the light emitting diode Az of display circuit 7, the end of the foot 15 connecting resistance R8 of chip U1 and the quiet end i-3 of impulse waveform permutator i; The other end ground connection of resistance R 8; The foot 11 of chip U1 connects an end of the resistance R 4 of dilatational wave output circuit 4, and the foot 14 of chip U1 connects an end of the resistance R 5 of dilatational wave output circuit 4, and the foot 16 of chip U1 connects an end of the resistance R 10 of square wave output circuit 5; The foot 17 of chip U1 connects an end of the resistance R 9 of booster circuit 6; The foot 20 of chip U1 meets an end of capacitor C 7, the positive pole and the power supply Vc of capacitor C 8, and the end of the foot 1 connecting resistance R3 of chip U1 and the negative pole of capacitor C 8, the other end of the other end of resistance R 3 and capacitor C 7 are connected and ground connection; Foot 10 ground connection of chip U1, the foot 3 of chip U1, foot 6 to foot 9, foot 12, foot 13 are unsettled.The model of chip U1 is 89C2051, storage program among the chip U1, and C7, C8 and R3 form the reset circuit of U1; A7, C5 and C6 form the clock circuit of U1; Behind quiet end i-3 and moved end i-5 connection and moved end i-4 and quiet end i-1 connection that impulse waveform permutator i is set to, the foot 15 of chip U1 is in high potential, the square-wave pulse signal of the α frequency of the foot 16 output low amplitude value of chip U1; The foot 19 of chip U1 is alternately exported high-low level simultaneously, and light emitting diode An is constantly glimmered; The quiet end i-3 that becomes as impulse waveform permutator i and moved end i-5 disconnects and moved end i-4 and quiet end i-2 when connecting; The foot 15 of chip U1 is in electronegative potential; The foot 16 of chip U1 is no longer exported the square-wave pulse signal of α frequency, and the foot 19 of chip U1 becomes low level simultaneously, and the foot 18 of chip U1 is alternately exported high-low level; Light emitting diode Az is constantly glimmered, the dilatational wave pulse signal of the foot 11 of chip U1 and two groups of opposite each other low amplitude value of foot 14 outputs.Chip U1 is through the voltage boosting pulse signal of foot 17 to booster circuit 6 output high frequencies.
As shown in Figure 5; Dilatational wave output circuit 4 is made up of four resistance R 4-R7, six audion G5-G10; The foot 14 of the chip U1 of one termination pulse signal generation circuit 3 of resistance R 5; The base stage of another termination audion G9 of resistance R 5; The end of the colelctor electrode connecting resistance R7 of audion G9, the base stage of audion G5 and the base stage of audion G7; The emitter stage of audion G9 connects emitter stage and the ground connection of audion G10; The emitter stage of the end of the other end connecting resistance R6 of resistance R 7, the emitter stage of audion G5, audion G6 and the quiet end i-2 of impulse waveform permutator i, the colelctor electrode of another termination audion G10 of resistance R 6, the base stage of audion G6 and the base stage of audion G8, the colelctor electrode of the colelctor electrode of audion G7 and audion G8 is connected and ground connection; The base stage of one termination audion G10 of resistance R 4; The foot 11 of the chip U1 of another termination pulse signal generation circuit 3 of resistance R 4, the emitter stage of audion G5 connect the emitter stage of audion G7 and are connected with the foot g-2 of dilatational wave accessory power outlet g and the contact pin j-4 of field effect medicated cap accessory power outlet j, and the emitter stage of audion G6 connects the emitter stage of audion G8 and is connected with the foot g-1 of dilatational wave accessory power outlet g and the contact pin j-3 of field effect medicated cap accessory power outlet j.The quiet end i-3 that becomes as impulse waveform permutator i and moved end i-5 disconnects and moved end i-4 and quiet end i-2 when connecting; The foot 15 of chip U1 is in electronegative potential; The foot 16 of chip U1 is no longer exported the square-wave pulse signal of α frequency, and the foot 19 of chip U1 becomes low level simultaneously, and the foot 18 of chip U1 is alternately exported high-low level; Light emitting diode Az is constantly glimmered; The dilatational wave pulse signal of the foot 11 of chip U1 and two groups of opposite each other low amplitude value of foot 14 outputs, when foot 11 output high level feet 14 output low levels, G10 conducting, G9 end; Thereby G6, G7 are by, G5, G8 conducting; Make the dilatational wave pulse signal that produces a reverse amplitude between foot g-1 and the foot g-2 of dilatational wave accessory power outlet g and between the contact pin j-3 of field effect medicated cap accessory power outlet j and the contact pin j-4, when foot 11 output low level feet 14 output high level, G10 is by, G9 conducting; Thereby G6, G7 conducting, G5, G8 end; Make the dilatational wave pulse signal that produces the amplitude of a forward between foot g-1 and the foot g-2 of dilatational wave accessory power outlet g and between the contact pin j-3 of field effect medicated cap accessory power outlet j and the contact pin j-4, between the foot g-1 of dilatational wave accessory power outlet g and the foot g-2 and between the contact pin j-3 of field effect medicated cap accessory power outlet j and the contact pin j-4 under the control of chip U1 the dilatational wave pulse current of the amplitude of an alternation of generation, this dilatational wave pulse current acts on the corresponding acupuncture point of people's head through a plurality of electrode p in field effect medicated cap accessory power outlet j, the field effect medicated cap B; Thereby activate the brain cell that is in inhibitory state; Adjust corticocerebral excitement and process of inhibition, regulate neuro function, the raising cerebral tissue is to the synthetic of material and utilize ability; This dilatational wave pulse current plays the effect of electroacupuncture treatment through the limbs that dilatational wave accessory power outlet g and self-adhering electrode C act on the people.
As shown in Figure 5, square wave output circuit 5 is made up of three resistance R 10-R12, audion G3, audion G4, the foot 16 of a termination pulse signal generation circuit 3 chip U1 of resistance R 10; The base stage of another termination audion G4 of resistance R 10, the end of the colelctor electrode connecting resistance R11 of audion G4 and the base stage of audion G3, another termination power of resistance R 11; The emitter stage of the emitter stage of audion G4 and audion G3 is connected and ground connection, and the end of the colelctor electrode connecting resistance R12 of audion G3 also is connected the quiet end i-1 of another termination impulse waveform permutator i of resistance R 12 with the foot h-2 of square wave accessory power outlet h; The foot h-1 ground connection of square wave accessory power outlet h; Behind quiet end i-3 and moved end i-5 connection and moved end i-4 and quiet end i-1 connection that impulse waveform permutator i is set to, the foot 15 of chip U1 is in high potential, and the foot 19 of chip U1 is alternately exported high-low level; Light emitting diode An is constantly glimmered; The square-wave pulse signal of the α frequency of the foot 16 output low amplitude value of chip U1 makes audion G4 control audion G5 turn-off and conducting by the α frequency simultaneously, thereby makes the square wave pulsed current of the α frequency of square wave output circuit 5 output amplitude; The square wave pulsed current of this α frequency acts on the relevant acupuncture point of ear through square wave accessory power outlet h, the electrode D of ear; Can reflexive stimulation cerebral cortex, promote neural comprehensive recovery, not only can improve health, improve immunity; Strengthen attention; Improving memory and audition, the prevention senile dementia also can play significant rehabilitation effect to various cerebrovascular disease.
As shown in Figure 5; Booster circuit 6 is made up of resistance R 9, R13, R14, R15, audion G1, G2, capacitor C 9, C10, inductance DG, diode D3 and potentiometer W2; One termination pulse signal generation circuit 3 of resistance R 9 is by the foot 17 of chip U1; The base stage of another termination audion G1 of resistance R 9; The end of the colelctor electrode connecting resistance R15 of audion G1 and the base stage of audion G2; The end of the other end of resistance R 15 and inductance DG is connected and connects power supply; The emitter stage of anodal audion G2 that the colelctor electrode of audion G2 meets the other end and the diode D3 of inductance DG connects the emitter stage of audion G1, an end of capacitor C 9, the negative pole of capacitor C 10, an end and the ground connection of resistance R 13, and the negative pole of diode connects the other end of capacitor C 9, the positive pole of capacitor C 10, an end of resistance R 14, the end of another termination potentiometer W2 of resistance R 14; The other end of another termination connecting resistance R13 of potentiometer W2; The slider of potentiometer W2 meets an end and the moved end i-4 of impulse waveform permutator i of the resistance R 16 of display circuit 7, and the inductance nominal value of inductance DG is 2.2 milihenries, and pulse signal generation circuit 3 makes inductance DG energy storage formation high frequency, high-voltage pulse by the foot 17 output high frequency voltage boosting pulse signals of the chip U1 on-off action through audion G1, G2; Filtering and energy storage effect through capacitor C 9, C10 produce high voltage direct current stably, and the adjusting of process potentiometer W2 makes booster circuit 6 output amplitudes continuously adjustable DC voltage between 0-100v.
As shown in Figure 5, display circuit 7 is made up of chip U3,12 resistance R 16-R27, light emitting diode An, A1, A2, A3, A4, Az and potentiometer W1, the slider of the potentiometer W2 of a termination booster circuit 6 of resistance R 16; The end of another termination potentiometer W1 of resistance R 16, the other end ground connection of potentiometer W1, the slider of potentiometer W1 connects foot 2, foot 6, the foot 13 of chip U3; The end of the foot 10 connecting resistance R21 of chip U3 and an end of resistance R 20, the other end ground connection of resistance R 21, the foot 5 of another chip termination U3 of resistance R 20 and an end of resistance R 19; The foot 3 of another chip termination U3 of resistance R 19 and an end of resistance R 18, the foot 12 of another chip termination U3 of resistance R 18 and an end of resistance R 17, another termination power of resistance R 17; Foot 11 ground connection of chip U3, the foot 4 of chip U3 connects power supply, the negative pole of the foot 8 sending and receiving optical diode A1 of chip U3; The end of the anodal connecting resistance R23 of light emitting diode A1, the negative pole of the foot 7 sending and receiving optical diode A2 of chip U3, the end of the anodal connecting resistance R24 of light emitting diode A2; The negative pole of the foot 1 sending and receiving optical diode A3 of chip U3, the end of the anodal connecting resistance R25 of light emitting diode A3, the negative pole of the foot 14 sending and receiving optical diode A4 of chip U3; The end of the anodal connecting resistance R26 of light emitting diode A4; The negative pole of light emitting diode An connects the foot 19 of pulse signal generation circuit 3 chip U1, and the end of the anodal connecting resistance R22 of light emitting diode An, the negative pole of light emitting diode Az connect the foot 18 of pulse signal generation circuit 3 chip U1; The end of the anodal connecting resistance R27 of light emitting diode Az; The other end of six resistance R 22-R27 interconnects and connects power supply, and the model of chip U3 is LM324, and light emitting diode An, Az receive the control of signal generating circuit 3 to show duty of the present invention; Light emitting diode A1 to A4 shows the different voltage magnitudes of potentiometer W2 output; When adjustment potentiometer W2 raise the voltage magnitude of output, the diode A1 to A4 that gives out light lighted successively, otherwise extinguishes successively with reverse order.
As shown in Figure 5; Field signal generation circuit 8 is made up of five resistance R 28-R32, chip U4, controllable silicon Q1, diode D1, D2 and magnetic field intensity selector switch k; One termination power of resistance R 28; The foot 1 of another chip termination U4 of resistance R 28, foot 2 ground connection of chip U4; The end of the foot 6 connecting resistance R29 of chip U4, another termination silicon controlled one end of resistance R 29 and the foot X3 of transformator T1, the negative pole of another terminating diode of silicon controlled D1 and the positive pole of diode D2; Silicon controlled triggers the foot 4 of chip termination U4; Foot 3, the foot 5 of chip U4 are unsettled, and the negative pole of the positive pole of diode D1 and diode D2 is connected and is connected the moved end of the other end connecting resistance R31 of resistance R 30, the end of R32 and magnetic field intensity selector switch k with an end of resistance R 30; The quiet end of the other end of resistance R 31, R32 and magnetic field intensity selector switch k is connected and is connected with the j-1 contact pin of field effect medicated cap accessory power outlet j; The j-1 contact pin is connected with the end of lead with the inner electric magnet y that distributes of field effect medicated cap B through field effect medicated cap B plug, and the other end of electric magnet y is connected with the j-2 contact pin of lead with field effect medicated cap accessory power outlet j through field effect medicated cap B plug, and the foot X4 of j-2 contact pin and transformator T1 is connected; The model of chip U4 is MOC3010; Controlling magnetic field signal generating circuit 8 through chip U4 can be exported alternating current, makes the inner a plurality of electric magnet y that distribute of field effect medicated cap B produce alternating magnetic fields, and the alternating magnetic field that utilizes the layout of electric magnet locus in field effect medicated cap B that electric magnet y is sent forms three-dimensional stack alternating magnetic field V in people's brain ganglion basal zone.
In conjunction with Fig. 2 and shown in Figure 3, electric magnet be 1-8, each electric magnet connects the back in parallel and links to each other with brain electrical analogue generator.Electrode is at least one pair of, and the both positive and negative polarity of every counter electrode is installed in the field effect medicated cap, and positive and negative electrode is symmetrically distributed in the same plane Z, and the characteristic of plane Z is that directly to go up in the 6cm 2 line with the ears have sharp ears be axle, and planar angle is that the front end minimum point is to Yintang acupoint.
Another embodiment of the present invention is in field effect medicated cap inside guide rail to be installed, and the balladeur train that can on guide rail, move or lock is installed on the guide rail, and electric magnet and electrode are installed on the balladeur train separately.In field effect medicated cap inside at least one block permanent magnet is installed also.It also comprises self-adhering electrode, and self-adhering electrode links to each other with brain electrical analogue generator through lead.It also comprises a pair of ear electrode, and a pair of ear electrode links to each other with brain electrical analogue generator through lead.
Above-mentioned two kinds of embodiments mainly are suitable for treating brain diseasess such as parkinson, brain atrophy.
In conjunction with Fig. 6, it is on the basis of above-mentioned embodiment that the present invention also has a kind of embodiment, and the positive pole of electrode is installed in the field effect medicated cap, and negative pole is installed in the wrist strap.This technical scheme mainly is suitable for the treatment of epileptics.
Claims (4)
1. transcranial magnetic therapeutic instrument for computer diseases; It comprises can be with the field effect medicated cap at head; It is characterized in that: field effect medicated cap inside is distributed with electrode and at least one electric magnet, and it also comprises brain electrical analogue generator, and electric magnet links to each other with brain electrical analogue generator respectively through lead with electrode;
Described electric magnet is 2-8, and each electric magnet connects the back in parallel and links to each other with brain electrical analogue generator;
Described electrode is at least one pair of; The both positive and negative polarity of every counter electrode is installed in the field effect medicated cap; Positive and negative electrode is symmetrically distributed in the same plane Z, and the characteristic of plane Z is that directly to go up in the 6cm 2 line with the ears have sharp ears be axle, and planar angle is that the front end minimum point is to Yintang acupoint;
Described brain electrical analogue generator by housing, be installed on and off switch on the housing, dilatational wave accessory power outlet, square wave accessory power outlet, impulse waveform permutator, field effect medicated cap accessory power outlet, magnetic field intensity selector switch, pulse current functional indicator light, pulse current intensity display lamp and treatment signal generating circuit and constitute; Said treatment signal generating circuit is made up of DC power supply circuit, timing sounding electric circuit, pulse signal generation circuit, dilatational wave output circuit, square wave output circuit, booster circuit, display circuit, field signal generation circuit; The output termination of said DC power supply circuit is an input of sounding electric circuit, pulse signal generation circuit, square wave output circuit, booster circuit, display circuit regularly; Another input of an output termination booster circuit of pulse signal generation circuit; The outfan of booster circuit connects an input of dilatational wave output circuit and square wave output circuit respectively through the impulse waveform permutator; Two outfans of pulse signal generation circuit connect two inputs of dilatational wave output circuit respectively; The dilatational wave output circuit carries out this two-way dilatational wave signal to export through the contact pin of dilatational wave accessory power outlet and field effect medicated cap accessory power outlet after the power amplification; The dilatational wave accessory power outlet connects a pair of self-adhering electrode through plug and lead; The contact pin of field effect medicated cap accessory power outlet connects the electrode in the field effect medicated cap through plug and lead; An input of an output termination square wave output circuit of pulse signal generation circuit, the square wave output circuit carries out square-wave signal to export through the square wave accessory power outlet after the power amplification, and the square wave accessory power outlet connects a pair of ear electrode through plug and lead; An input of the output termination display circuit of booster circuit; Two inputs of two output termination display circuits of pulse signal generation circuit, an output termination of pulse signal generation circuit is the input of sounding electric circuit regularly, the input of the output termination field signal generation circuit of DC power supply circuit; The outfan of field signal generation circuit is through the contact pin output of field effect medicated cap accessory power outlet, and the contact pin of field effect medicated cap accessory power outlet connects the electric magnet in the field effect medicated cap through plug and lead.
2. transcranial magnetic therapeutic instrument for computer diseases according to claim 1 is characterized in that: described field effect medicated cap inside is equipped with guide rail, and the balladeur train that can on guide rail, move or lock is installed on the guide rail, and electric magnet and electrode are installed on the balladeur train separately.
3. transcranial magnetic therapeutic instrument for computer diseases according to claim 2 is characterized in that: in field effect medicated cap inside at least one block permanent magnet is installed also.
4. transcranial magnetic therapeutic instrument for computer diseases according to claim 3 is characterized in that: described electrode comprises positive pole and negative pole, and positive pole is installed in the field effect medicated cap, and negative pole is installed in the wrist strap.
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| Publication number | Priority date | Publication date | Assignee | Title |
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| TWI638670B (en) | 2018-01-05 | 2018-10-21 | 鄭智隆 | Brain healthy device |
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| CN102580235A (en) * | 2012-02-24 | 2012-07-18 | 江苏苏云医疗器材有限公司 | Transcranial direct current stimulation instrument |
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| CN109199377A (en) * | 2017-07-03 | 2019-01-15 | 诺尔医疗（深圳）有限公司 | Intracranical deep electrode and medical instrument |
| CN108434597B (en) * | 2018-04-19 | 2023-11-07 | 南京市中医院 | Trigeminal nerve and occipital nerve distribution region acupoint combined electric stimulation headache therapeutic apparatus |
| CN109011156A (en) * | 2018-07-13 | 2018-12-18 | 河南省中医院（河南中医药大学第二附属医院） | Transcranial magnetic encephalopathy therapeutic apparatus |
| CN110141224A (en) * | 2019-05-06 | 2019-08-20 | 首都医科大学宣武医院 | Eeg monitoring protective device |
| CN112245800A (en) * | 2020-11-13 | 2021-01-22 | 胡楚凡 | Disposable portable memory and learning ability enhancement paste |
| CN114916939B (en) * | 2022-07-18 | 2022-11-08 | 中国科学院自动化研究所 | Wearable brain cognitive detection and regulation wireless closed-loop equipment and method |
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