CN101491655B - Traditional Chinese medicine composite for treating heart disease and preparation method thereof - Google Patents
Traditional Chinese medicine composite for treating heart disease and preparation method thereof Download PDFInfo
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- CN101491655B CN101491655B CN2008102282420A CN200810228242A CN101491655B CN 101491655 B CN101491655 B CN 101491655B CN 2008102282420 A CN2008102282420 A CN 2008102282420A CN 200810228242 A CN200810228242 A CN 200810228242A CN 101491655 B CN101491655 B CN 101491655B
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Abstract
The invention relates to a traditional Chinese medicine composition for treating heart diseases, and a preparation method thereof. The composition is prepared from the following raw materials in portion by weight: dry antler blood, deer tail powder, deer heart, calamus, sharpleaf galangal fruit, ginseng, ophiopogon roots, poria with hostood, honey-fried licorice roots, polygala roots, safflowers, Liaoning shizandra, fragrant solomonseal rhizome, angelica and rehmannia glutinosa of which the amount is according to a formulation. Medicinal liquids of ten of the raw materials are boiled, stewed, dried and pulverized so as to obtain a mixed medicine; the mixed medicine and deer heart powder are well mixed with dry antler blood and deer tail powder, sterilized and packed into capsules; and remaining polygala roots and safflowers are individually packed to be efficacy-enhancing ingredients. Clinical trial and statistical analysis prove that the traditional Chinese medicine composition is quick to take effect and short in treatment course, has the treatment rate of 98 percent during observation time, has no toxic-side effects, prevents myocardial infarction in case of long-term taking, and has the efficacy in protecting and preserving health. Return visit to cured patients shows that no recurrent case is found in more than two years.
Description
Technical field
The present invention relates to a kind of Chinese medicine composition, particularly a kind of cardiopathic Chinese medicine composition and preparation method thereof for the treatment of.The curative of the patient such as coronary heart diseases and angina pectoris and myocardial infarction first-selection.
Background technology
The pertinacious disease that well-known heart and brain core barrel disease has become obstinate, repeatedly shows effect and caused death, disability rate is high makes the patient bear huge fear and painful.Although the medicines such as nitrate esters, calcium antagonist, receptor blocking agent and antiplatelet drug for the treatment of coronary heart diseases and angina pectoris, myocardial infarction and heart failure was arranged on the market in the past, very large side effect is arranged usually.Can cause that such as nitrate esters headache is flushing, tinnitus is dizzy and tachycardia, sometimes also can cause blood pressure to plunge, cause collapse and produce drug resistance; Calcium antagonist mainly reduces cardiac load by coronary artery dilator and systemic arterial, is a kind of emergency treatment commonly used, yet blood vessel dilating is easy to cause that heart beating is excessively slow, heart failure and dependency are strong, and the hypotensive uses and can die suddenly; The dependency of receptor blocking agent is very strong, and suddenly drug withdrawal meeting makes the state of an illness more serious; Antiplatelet drug then can cause the side effect such as digestive tract hemorrhage.Otherwise consequence is not hardly imaginable.Because described pharmic function is single, is to cure the symptoms, not the disease.When the doctor uses above-mentioned treatment means when invalid repeatedly, just have an operation, fill support, heart pass etc.Cure the symptoms, not the disease although this still belongs to, be doctors for and helpless selection.
Content of the present invention
The present invention is directed to the problem that prior art exists, a kind of have blood circulation promoting and blood stasis dispelling, pure and impure strengthening vital QI to eliminate pathogenic factors are provided, and then make it recover gradually self function, enhancing immunity, promote endogenous blood circulation promoting and blood stasis dispelling, get rid of fast speckle, effectively anti-hemostatic tube rubbish deposits again, fundamentally eliminate arteriosclerosis, the prevention myocardial infarction, to all kinds of heart diseases all effectively, the instant effect curative effect is lasting, effectively and cure rate high, have no side effect, short treating period cures and do not recur, treating both the principal and secondary aspects of a disease is used for the treatment of cardiopathic Chinese medicine composition and preparation method thereof.
Another object of the present invention is all to bring into play simultaneously therapeutical effect with Chinese medicine composition of the present invention to causing cardiopathic a plurality of risk factor, overcame in the past and treated for different risk factor wherein respectively with multiple medicine, also Just because of this, not only often but also cause new drug-induced disease and the drawback of multiple complications.
Chinese medicine composition of the present invention be by following raw materials according by weight through being prepared from:
Do Sanguis Cornu Cervi Pantotrichum 3-6 Cauda cervi powder 6-12 Cor Cervi 120-130 Rhizoma Acori Graminei 6-15 Fructus Alpiniae Oxyphyllae 10-17 Radix Ginseng 10-20 Poria cum Radix Pini's 25-30 Radix Ophiopogonis 15-20 Radix Glycyrrhizae Preparata 4-9 Radix Polygalae 5-6 Flos Carthami 2-3 FRUCTUS SCHISANDRAE from Liaoning of China 10-18 Rhizoma Polygonati Odorati 23-35 Radix Angelicae Sinensis 12-14 Radix Rehmanniae Preparata 25-35.
Chinese medicine composition of the present invention, wherein the ratio of weight and number of each raw material is;
Do Sanguis Cornu Cervi Pantotrichum 3-4 Cauda cervi powder 7-10 Cor Cervi 120-125 Rhizoma Acori Graminei 8-10 Fructus Alpiniae Oxyphyllae 10-15 Radix Ginseng 12-15 Poria cum Radix Pini's 26-28 Radix Ophiopogonis 16-18 Radix Glycyrrhizae Preparata 5-7 Radix Polygalae 5-6 Flos Carthami 2-3 FRUCTUS SCHISANDRAE from Liaoning of China 12-15 Rhizoma Polygonati Odorati 25-30 Radix Angelicae Sinensis 12-13 Radix Rehmanniae Preparata 28-30.
Chinese medicine composition of the present invention, wherein the weight proportion of each raw material is:
Do Sanguis Cornu Cervi Pantotrichum 6 Cauda cervi powder 9 Cor Cervi 125 Rhizoma Acori Gramineis 10 Fructus Alpiniae Oxyphyllae 17 Radix Ginsengs 27 Poria cum Radix Pinis, 15 Radix Glycyrrhizae Preparatas, 15 Radix Ophiopogonis 4 Radix Polygalaes 6 Flos Carthamis 3 FRUCTUS SCHISANDRAE from Liaoning of China 10 Rhizoma Polygonati Odorati 23 Radix Angelicae Sinensis 12 Radix Rehmanniaes Preparata 25.
The preparation method of Chinese medicine composition of the present invention, its processing step is as follows:
1), Sanguis Cornu Cervi Pantotrichum is done in preparation: it is for subsequent use that the fresh Sanguis Cornu Cervi Pantotrichum that will gather enters far infrared stove oven dry levigation;
2), the preparation of Cauda cervi powder: bright Cauda cervi is entered in the boiling water 5-6 pull out second with calico Bao Yanhou and reenter in the boiling water 0.5 minute, take out tying in the plastic bag, put shady and cool place 24 hours, purify except the outsourcing thing enters the cold water scoured wool, put shady and cool ventilation place three again and say, the oven dry levigation is for subsequent use;
3), the preparation of Cor Cervi powder: measure Rhizoma Acori Graminei, Fructus Alpiniae Oxyphyllae, Radix Ginseng, Radix Ophiopogonis, Poria cum Radix Pini, Radix Glycyrrhizae Preparata, FRUCTUS SCHISANDRAE from Liaoning of China, Rhizoma Polygonati Odorati, Radix Angelicae Sinensis and Radix Rehmanniae Preparata by prescription and enter the water extractive that adds three times of drug weight in the nonmetallic vessel, boil and got liquid in rear little fiery 40 minutes, successively decrease successively again and add two times, one times water, boiled rear 30 minutes and 10 minutes, three medicinal liquids are mixed, the Cor Cervi that adds formula ratio boils, takes out chopping, again enters the little fire of medicinal liquid and boils to medicinal liquid and be thick, and ceasing fire, it is for subsequent use to take out together the oven dry levigation;
4) the dried Sanguis cervi, Cauda cervi powder of, getting formula ratio add 3) stir sterilization, encapsulated, 0.4g/ grain in the hybrid medicine powder of step;
5), Radix Polygalae, the Flos Carthami of getting formula ratio be packaged as separately extra conductant ingredient, before taking medicine, fry in shallow oil moisture and become 14 equal portions for subsequent use.
Prescription of the present invention is for all kinds of cardiopathic pathogenic factors, and scientific composition makes its performance synergistic function, promotes internal organs self functional rehabilitation, eliminates symptom and reaches the principles of formulating prescriptions that rehabilitation has no side effect again.As Rhizoma Acori Graminei, Rhizoma Polygonati Odorati and Radix Ophiopogonis in the prescription having happy key, improving the myocardial ischemia function; And for example Sanguis Cornu Cervi Pantotrichum, Cor Cervi, Cauda cervi, Radix Angelicae Sinensis and Radix Rehmanniae Preparata compatibility have preferably QI invigorating effect; Radix Ginseng, FRUCTUS SCHISANDRAE from Liaoning of China and Radix Glycyrrhizae Preparata have two-way conciliation effect, play raising autoimmunity in we, improve the cardiac cycle function; Fructus Alpiniae Oxyphyllae, fortune will Flos Carthami can be steady and heart, blood circulation promoting, improve vascular function, and can play blood vessel street cleaner's effect.Above-mentioned all flavor medicine compatibilities are given full play to synergistic function, and through the proof of clinical trial
The present invention compared with prior art and has the following advantages and good effect through clinical trial proof:
1, Chinese medicine of the present invention is comprehensively reconciled indication, and treating both the principal and secondary aspects of a disease reaches the healing rehabilitation, eliminates a plurality of symptoms in the past controlled respectively a kind of disease with multiple medicine, cure the symptoms, not the disease and side effect large, often cause new drug-induced disease and the drawback of complication;
2, indication instant effect, short treating period, effective percentage are reached 98%, cure and do not recur, follow up a case by regular visits to no recurrence in 2 years to curing patient's tracking;
3, nontoxic to human body, long-term taking is impairing the liver kidney no dependence not, and prevention of cardiac and body building health-care effect are arranged;
4, alleviate patient's financial burden, eliminate patient's Psychological phobia and mental suffering, improve the quality of living.
The specific embodiment
Embodiment 1
1), do the preparation of Sanguis Cornu Cervi Pantotrichum: the fresh Sanguis Cornu Cervi Pantotrichum that will gather enters the far infrared stove oven dry, levigation is for subsequent use;
2), the preparation of Cauda cervi powder: bright Cauda cervi entered 5-6 pulls out second in the boiling water, reenter in the boiling water 0.5 minute with calico Bao Yan, take out plastic bag and tighten mouth, put shady and cool place 24 hours, except the outsourcing thing enters that scoured wool purifies in the cold water, put shady and cool place post-drying on the three, levigation is for subsequent use;
3), the preparation of Cor Cervi powder: measure 30 parts in 15 parts of Rhizoma Acori Gramineis, 10 parts of Fructus Alpiniae Oxyphyllae, 20 parts of Radix Ginsengs, 25 parts of Radix Ophiopogonis, 15 parts of Poria cum Radix Pinis, 7 parts of Radix Glycyrrhizae Preparatas, 14 parts of FRUCTUS SCHISANDRAE from Liaoning of China, 29 parts of Rhizoma Polygonati Odorati, 13 parts of Radix Angelicae Sinensis and Radix Rehmanniae Preparata by prescription and enter nonmetallic vessel, add the heavy decocting juice of three times of medicines, boil and got liquid in rear little fiery 40 minutes, successively decrease again to add respectively to be respectively after two times, one times water boils and fried in shallow oil juice in 30 minutes and 10 minutes, three medicinal liquid mixing and stirring add 130 parts of Cor Cervi boils, takes out the Cor Cervi chopping and reenter the medium and small fire of medicinal liquid and be thick to medicinal liquid, and the oven dry levigation is for subsequent use;
4), respectively from 1), 2) get do 6 parts of 3 parts of Sanguis Cornu Cervi Pantotrichum, Cauda cervi powder and enter 3) mixed powder in stir rear sterilization, encapsulated 0.4g/ grain;
5), get 5 parts of Radix Polygalaes and 2 parts of Flos Carthamis are packed separately, before taking, enter container and add three times of heavy decocting juice of medicine to be divided into 14 equal portions to 500-600mL be extra conductant ingredient, with boiled water that the medicine clothes are lower when taking medicine.
Example 2, get 10 parts of Rhizoma Acori Gramineis, 17 parts of Fructus Alpiniae Oxyphyllae, 15 parts of Radix Ginsengs, 27 parts of Radix Ophiopogonis, 15 parts of Poria cum Radix Pinis, 4 parts of Radix Glycyrrhizae Preparatas, 10 parts of FRUCTUS SCHISANDRAE from Liaoning of China, 23 parts of Rhizoma Polygonati Odorati, 12 parts of Radix Angelicae Sinensis, 25 parts in Radix Rehmanniae Preparata, 125 parts of Cor Cervi; Do 6 parts of Sanguis Cornu Cervi Pantotrichum, 9 parts in Cauda cervi powder; 3 parts of 6 parts of Flos Carthami of Radix Polygalae.Its preparation method is identical with embodiment 1.
Example 3, get 6 parts of Rhizoma Acori Gramineis, 13 parts of Fructus Alpiniae Oxyphyllae, 10 parts of Changbai Mountain Radix Ginsengs, 30 parts of Radix Ophiopogonis, 20 parts of Poria cum Radix Pinis, 9 parts of Radix Glycyrrhizae Preparatas, 18 parts of FRUCTUS SCHISANDRAE from Liaoning of China, 35 parts of Rhizoma Polygonati Odorati, 14 parts of Radix Angelicae Sinensis, 35 parts in Radix Rehmanniae Preparata, 120 parts of Cor Cervi; Do 4 parts of Sanguis Cornu Cervi Pantotrichum, 12 parts in Cauda cervi powder; 2 parts of 5 parts of Flos Carthami of Radix Polygalae.Preparation method is identical with embodiment 1.
For further examining the curative effect of medicine of the present invention, 150 examples suffered from coronary heart disease and anginal patient carries out clinical trial, in the identical or approximate situation of patient's the state of an illness, fall ill time and doctor's technical conditions, compare, clinical observation 1 year, curative effect of medication of the present invention is remarkable, the instant effect short treating period, and effective percentage is high, cure and do not recur, its observed result is reported as follows:
One, clinical data:
The case history that clinical verification is selected all meets the requirements of defined in the checking design, and take the case history of being in hospital as main, patient medical history is auxiliary, observes 150 examples, test group 100 examples wherein, matched group 50 examples.Each is organized sex, age and sees Table 1.Disease symptoms sees Table 2.
Each test group sex of table 1, age
Table 2 disease symptoms
Two, dosage and method:
Test group: medicine of the present invention, every day secondary, one hour after meal each 32 morning and evenings, the extra conductant ingredient warm water is taken, one month is a course for the treatment of.
Matched group: the Radix Notoginseng electuary, every day 3 times, each 2 grams, the empty stomach warm boiled water, one month is a course for the treatment of.In test, cut out the medicine of other treatment coronary heart disease and angina pectoris class.
Three, criterion of therapeutical effect and judgement:
Recovery from illness: coronary heart disease and angina pectoris symptom complete obiteration.
Produce effects: coronary heart disease and angina pectoris symptom, the most of disappearance.
Invalid: coronary heart disease and angina pectoris symptom improve not obvious.
Therapeutic outcome is judged:
Efficient statistics and significance compare: the comparison sheet X of test group and matched group Different therapeutical effect
2The statistical processing methods of test:
The efficient statistics of table 3
Through X
2Check, the total effective rate of test group reaches 98%, and the matched group total effective rate is 66%, and test group and matched group Different therapeutical effect are remarkable.
Table 4 effectively compares the course for the treatment of
The effectively comparative analysis course for the treatment of: the test group treatment shortest time is 30-90 days, and what reach effective standard is 98%.
Matched group: treatment time reached more than 90 days, and what reach effective standard accounts for 66%, test group and matched group significant difference.
From this group clinical statistics, the total effective rate of medicine of the present invention, observing time the internal therapy rate be 98%.And the effective percentage of matched group medicine within observing time is 66%.
Statistical analysis is processed: both effective percentage have significant difference, and the effect of the treatment of test group is fast, and short treating period is better than the matched group medicine.
Four, untoward reaction:
Use clinical drug of the present invention 100 routine patients are carried out complete observation, period in a medicine has the local head of individual patient or brothers to wait the place slight fiber crops to occur, expand, bitterly, this is stimulate the menstrual flow the in vivo normal reaction of blood stasis dispelling effect of pharmic function, one, two day at least, to die away in three, five days at most, the part case history was followed up a case by regular visits to after 1 year, all do not find any untoward reaction.
Five, clinical experience
By adopting Drug therapy coronary heart diseases and angina pectoris of the present invention and hypertensive heart disease, received satisfied curative effect.These sick symptoms are a lot, and it is to make a definite diagnosis in general hospital and section hospital's diagnosis to belong to coronary heart disease and angina pectoris is cured that modal uncomfortable in chest, chest pain, palpitation and short breath, both hands numbness, vertigo and tinnitus, weak insomnia clinical treatment are selected in this clinical trial.
According to efficient statistics, the total effective rate 98% of test group, matched group total effective rate are 66%, and test group and matched group Different therapeutical effect are remarkable.
The therapeutic effect of experimental group is fast, and short treating period is better than the matched group medicine.
Medicine of the present invention; using dialectical the executing of theory of Chinese medical science controls; carry out heart, the whole conditioning of Liver and kidney; the patient is without any toxicity, and long-term taking not only prevents heart infarction to also have health care's effect, and is fast to the indication curative effect, effect is remarkable; its effective percentage reaches 98%; only have 2% case not by specification take medicine, it is invalid to cause, and then does not obtain rehabilitation.2 years of having through return visit of patient after the above healing do not have to find to have the case of recurrence.
Claims (3)
1. one kind is used for the treatment of cardiopathic Chinese medicine composition, it is characterized in that by following raw materials according by following weight portion through being prepared from:
Do Sanguis Cornu Cervi Pantotrichum 3-6 Cauda cervi powder 6-12 Cor Cervi 120-130 Rhizoma Acori Graminei 6-15 Fructus Alpiniae Oxyphyllae 10-17 Radix Ginseng 10-20 Poria cum Radix Pini's 25-30 Radix Ophiopogonis 15-20 Radix Glycyrrhizae Preparata 4-9 Radix Polygalae 5-6 Flos Carthami 2-3 FRUCTUS SCHISANDRAE from Liaoning of China 10-18 Rhizoma Polygonati Odorati 23-35 Radix Angelicae Sinensis 12-14 Radix Rehmanniae Preparata 25-35.
2. Chinese medicine composition according to claim 1 is characterized in that the weight proportion of each raw material is: do Sanguis Cornu Cervi Pantotrichum 3-4 Cauda cervi powder 7-10 Cor Cervi 120-125 Rhizoma Acori Graminei 8-10 Fructus Alpiniae Oxyphyllae 12-15 Radix Ginseng 12-15 Poria cum Radix Pini's 26-28 Radix Ophiopogonis 16-18 Radix Glycyrrhizae Preparata 5-7 Radix Polygalae 5-6 Flos Carthami 2-3 FRUCTUS SCHISANDRAE from Liaoning of China 12-15 Rhizoma Polygonati Odorati 25-30 Radix Angelicae Sinensis 12-13 Radix Rehmanniae Preparata 28-30.
3. Chinese medicine composition according to claim 1 is characterized in that the weight proportion of each raw material is: do Sanguis Cornu Cervi Pantotrichum 6 Cauda cervi powder 9 Cor Cervi 125 Rhizoma Acori Gramineis 10 Fructus Alpiniae Oxyphyllae 17 Radix Ginsengs 27 Poria cum Radix Pinis, 15 Radix Glycyrrhizae Preparatas, 15 Radix Ophiopogonis 4 Radix Polygalaes 6 Flos Carthamis 3 FRUCTUS SCHISANDRAE from Liaoning of China 10 Rhizoma Polygonati Odorati 23 Radix Angelicae Sinensis 12 Radix Rehmanniaes Preparata 25.
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| Application Number | Priority Date | Filing Date | Title |
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| CN2008102282420A CN101491655B (en) | 2008-10-24 | 2008-10-24 | Traditional Chinese medicine composite for treating heart disease and preparation method thereof |
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| CN101491655B true CN101491655B (en) | 2013-04-17 |
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1334121A (en) * | 2001-08-31 | 2002-02-06 | 石家庄以岭药业有限公司 | Medicinal composition for restoring cardiac collaterals and its application |
| CN101249207A (en) * | 2007-02-24 | 2008-08-27 | 赵继民 | Medicament prescription for treating coronary heart disease |
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- 2008-10-24 CN CN2008102282420A patent/CN101491655B/en not_active Expired - Fee Related
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1334121A (en) * | 2001-08-31 | 2002-02-06 | 石家庄以岭药业有限公司 | Medicinal composition for restoring cardiac collaterals and its application |
| CN101249207A (en) * | 2007-02-24 | 2008-08-27 | 赵继民 | Medicament prescription for treating coronary heart disease |
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