CN101491572A - Medicine for treating calculus and preparation method thereof - Google Patents
Medicine for treating calculus and preparation method thereof Download PDFInfo
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- CN101491572A CN101491572A CNA2009100739120A CN200910073912A CN101491572A CN 101491572 A CN101491572 A CN 101491572A CN A2009100739120 A CNA2009100739120 A CN A2009100739120A CN 200910073912 A CN200910073912 A CN 200910073912A CN 101491572 A CN101491572 A CN 101491572A
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Abstract
The invention relates to a drug for treating calculi. Ventriculi galli mucosa, desmodium and spora lygodii are added with water and decocted for three times; decoction is combined and condensed to form plaster with relative density of 1.2(50 DEG C); the plaster is dried and pulverized into drug powders; and the drug powders are filled to a capsule, sterilized and disinfected to prepare a capsule product. The drug clears away heat and removes dampness, is used for treating biliary calculi and urinary calculi, can change calculi from big to small, removes calculi outside human body, is easy for a patient to take, overcomes the disadvantages of large wound and small application range of western medicine treatment and is particularly suitable for the old and weak and people unsuitable for surgery. Through clinical observation, the total effective rate reaches 90 percent. The invention is the drug for treating calculi and the method for preparing the same.
Description
Technical field
The present invention relates to a kind of medicine for the treatment of calculus, particularly relating to a kind of is the treatment Biliary Calculi of feedstock production, the medicine of urinary stone with Chinese medicine.The invention still further relates to the preparation method of this medicine.
Background technology
Calculus comprises liver and bile stone, renal calculus, ureteral calculus, vesical calculus and calculus of urethra, the sickness rate height, distribute wide, during outbreak patient's pain unbearably, serious meeting causes the complication of a series of harm patient body health.
Mainly be operative therapy to Iithiasic treatment at present, its shortcoming is to cause very big misery, expense height and easily recurrence to patient, simultaneously patient is had wound in various degree even can cause a lot of sequela.The normal calculus medicine that uses has danshitong capsules, lithagogue infusion and uralyt, its shortcoming be Time of Administration long, absorb slow and don't lasting, particularly also be subjected to the restriction of stone location, size, what and composition, the logical cholelithiasis that can only be used for less than 1cm of cholelithiasis is invalid to nephrolith disease; Uralyt can only be used for the urinary system calculus less than 1.2cm, and is invalid to cholelithiasis.
Chinese medicine calculus not only toxic and side effects is little, and drug effect is remarkable.The advantage and the characteristic of performance Chinese medicine, Iithiasic Chinese medicine medicine is treated in further investigation and exploitation, can improve patient's quality of life, for extensive patients brings glad tidings, has the wide development prospect.
Summary of the invention
The purpose of this invention is to provide a kind of medicine for the treatment of calculus, this medicine has clearing away heat-damp and promoting diuresis, removing food stagnancy calculi dissolving effect, can be used for treating Biliary Calculi and urinary stone, can make maximum sizeization little, and progressively excrete.
Medicine of the present invention is that crude drug prepares by following parts by weight of traditional Chinese medicines:
Endothelium Corneum Gigeriae Galli 10～30 Herba Lysimachiaes 30～90
Spora Lygodii 10～20.
Further, medicine of the present invention is that crude drug prepares by following parts by weight of traditional Chinese medicines:
Endothelium Corneum Gigeriae Galli 10～30 Herba Lysimachiaes 30～90
Spora Lygodii 10～20 Radix Et Rhizoma Rhei 3～6
Rhizoma Corydalis 5～10.
Medicine of the present invention can also be that crude drug prepares by following parts by weight of traditional Chinese medicines:
Endothelium Corneum Gigeriae Galli 10～30 Herba Lysimachiaes 30～90
Spora Lygodii 10～20 Caulis Akebiaes 1～2
Succinum 2～5.
Said medicine can be made any dosage form on the pharmaceutics, as tablet, pill, powder, capsule etc., the preferred dosage form of the present invention is a capsule.
The concrete preparation method of medicine of the present invention being made capsule is:
Above-mentioned Chinese medicine is pressed described parts by weight mix homogeneously, decoct with water 3 times, each 1～2 hour, merge 3 times decocting liquid, filter, being condensed into relative density is the clear paste of 1.0～1.2 (50 ℃), after 50～60 ℃ of dryings, be ground into 100～120 medicated powder, in incapsulating, sterilization makes the capsule product.
In the prescription of the present invention, Endothelium Corneum Gigeriae Galli is sweet, cold, returns spleen, stomach, small intestinal, urinary bladder channel, promoting digestion and invigorating the stomach, arresting seminal emission; Herba Lysimachiae is sweet, salty, be slightly cold, and returns liver, gallbladder, kidney, urinary bladder channel, inducing diuresis for treating stranguria syndrome, dampness removing jaundice eliminating, heat-clearing and toxic substances removing; Cold in nature, the sweet in the mouth of Spora Lygodii is returned bladder, small intestine meridian eliminating damp-heat, treating stranguria pain relieving.All medicines share, and clearing away heat-damp and promoting diuresis, removing food stagnancy fossil are used for the treatment of Biliary Calculi and urinary stone, can make calculus little by bigization, get rid of external.
Simultaneously, the present invention suitably adds Radix Et Rhizoma Rhei, Rhizoma Corydalis when the treatment Biliary Calculi; When the treatment of urinary tract calculus, suitably add Caulis Akebiae, succinum, can reach better therapeutic effect.
Pharmaceutical dosage form of the present invention is a capsule, and the patient is easy to take, and takes safety, has overcome the shortcoming that traditional western medical treatment wound is big, subject range is little, has reduced the patient suffering, is more suitable in old, incompatibility operator.
For further investigating the clinical efficacy and the safety of medicine of the present invention, we select 160 routine Biliary Calculis and urinary stone patient that the curative effect of Drug therapy calculus of the present invention has been carried out clinical observation.
160 routine cases are divided into two groups at random, every group 80 example.Male 56 examples in the matched group, women 28 examples; Biliary Calculi 42 examples, urinary stone 38 examples; Male 60 examples are organized in treatment, women 20 examples; Biliary Calculi 38 examples, urinary stone 42 examples.All cases are all diagnosed with reference to the diagnostic criteria of treatment biliary tract and Urolithiasis in " new Chinese medicine clinical research guideline ".
Matched group is used ursodesoxycholic acid 200mg treatment, every day 4 times merely.The treatment group adopts medicine of the present invention to treat.Two groups were all taken for 2 weeks continuously is 1 course of treatment.
Criterion of therapeutical effect
Draft with reference to " clinical disease diagnosis is according to curing the improvement standard " relevant criterion of therapeutical effect.Recovery from illness: after medication 1～2 course of treatment, clinical symptoms, sign all disappear, and the ultrasound diagnosis calculus disappears.Produce effects: after medication 1～2 course of treatment, clinical symptoms, sign obviously alleviate, and the ultrasound diagnosis calculus reduces more than 50%.Effectively: after medication 1～2 course of treatment, clinical symptoms, sign alleviate, and the ultrasound diagnosis calculus reduces below 50%.Invalid: after medication 1～2 course of treatment, clinical symptoms, sign do not have obvious improvement, and the ultrasound diagnosis calculus does not have significant change.
Curative effect comparative result after two groups of cases are treated sees Table 1.
Curative effect after the table 1 liang group case treatment relatively
The specific embodiment
Embodiment 1
Get Endothelium Corneum Gigeriae Galli 2500g, Herba Lysimachiae 6000g, Spora Lygodii 2500g, choose most impurity, screening dry in the sun, after the oven dry, decoct with water 3 times, each water 30Kg, decocted 2 hours, and merged 3 times decocting liquid, be condensed into the clear paste of relative density 1.2 (50 ℃), after 60 ℃ of dryings, be ground into 120 purpose medicated powder, in incapsulating, sterilization makes the capsule product.
Embodiment 2
Get Endothelium Corneum Gigeriae Galli 2000g, Herba Lysimachiae 8000g, Spora Lygodii 2000g, Radix Et Rhizoma Rhei 400g, Rhizoma Corydalis 600g, choose most impurity, screening dry in the sun, after the oven dry, decoct with water 3 times, each water 40Kg, decocted 2 hours, and merged 3 times decocting liquid, be condensed into the clear paste of relative density 1.1 (50 ℃), after 55 ℃ of dryings, be ground into 120 purpose medicated powder, in incapsulating, sterilization makes the capsule product.
Embodiment 3
Get Endothelium Corneum Gigeriae Galli 3000g, Herba Lysimachiae 5000g, Spora Lygodii 3000g, Caulis Akebiae 150g, succinum 350g, choose most impurity, screening dry in the sun, after the oven dry, decoct with water 3 times, each water 35Kg, decocted 2 hours, and merged 3 times decocting liquid, be condensed into the clear paste of relative density 1.1 (50 ℃), after 55 ℃ of dryings, be ground into 120 purpose medicated powder, in incapsulating, sterilization makes the capsule product.
Claims (5)
1, a kind of medicine for the treatment of calculus is that crude drug prepares by following parts by weight of traditional Chinese medicines:
Endothelium Corneum Gigeriae Galli 10～30 Herba Lysimachiaes 30～90
Spora Lygodii 10～20.
2, the medicine of treatment calculus according to claim 1 is characterized in that by following parts by weight of traditional Chinese medicines being that crude drug prepares:
Endothelium Corneum Gigeriae Galli 10～30 Herba Lysimachiaes 30～90
Spora Lygodii 10～20 Radix Et Rhizoma Rhei 3～6
Rhizoma Corydalis 5～10.
3, the medicine of treatment calculus according to claim 1 is characterized in that by following parts by weight of traditional Chinese medicines being that crude drug prepares:
Endothelium Corneum Gigeriae Galli 10～30 Herba Lysimachiaes 30～90
Spora Lygodii 10～20 Caulis Akebiaes 1～2
Succinum 2～5.
4,, it is characterized in that described medicine is made capsule according to the medicine of claim 1,2 or 3 described treatment calculus.
5, the preparation method of the medicine of the described treatment calculus of claim 4, be by described parts by weight mix homogeneously with above-mentioned Chinese medicine, decoct with water 3 times, each 1～2 hour, merge 3 times decocting liquid, filter, be condensed into 50 ℃ of relative densities and be 1.0～1.2 clear paste, after 50～60 ℃ of dryings, be ground into 100～120 medicated powder, in incapsulating, sterilization makes the capsule product.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA2009100739120A CN101491572A (en) | 2009-03-10 | 2009-03-10 | Medicine for treating calculus and preparation method thereof |
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| CNA2009100739120A CN101491572A (en) | 2009-03-10 | 2009-03-10 | Medicine for treating calculus and preparation method thereof |
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| CN101491572A true CN101491572A (en) | 2009-07-29 |
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Cited By (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102861134A (en) * | 2012-09-09 | 2013-01-09 | 王人杰 | Six-ingredient litholytic powder |
| CN103006895A (en) * | 2012-11-26 | 2013-04-03 | 李延 | Preparation of lithontriptic capsule |
| CN103212027A (en) * | 2013-04-08 | 2013-07-24 | 段玉婷 | Traditional Chinese medicine preparation for treating urinary calculus |
| CN103386032A (en) * | 2013-06-27 | 2013-11-13 | 陶殿华 | Chinese medicine for assisting with treatment of urinary calculus |
| CN103386079A (en) * | 2013-06-27 | 2013-11-13 | 陶殿华 | Chinese medicine for assisting with treatment of gallstones and preparation method thereof |
| CN103705797A (en) * | 2013-12-17 | 2014-04-09 | 陈中元 | Drug for treating kidney stones |
| CN103961635A (en) * | 2013-01-30 | 2014-08-06 | 蒋孝峰 | Traditional Chinese medicine for treating nephrolithiasis and gallstone |
| CN104324083A (en) * | 2014-10-30 | 2015-02-04 | 张立 | Pharmaceutical composition for treating kidney stones and preparation method of pharmaceutical composition |
| CN104398769A (en) * | 2014-11-29 | 2015-03-11 | 高春娟 | Medicament for treating lithangiuria and preparation method thereof |
| CN105326911A (en) * | 2014-08-11 | 2016-02-17 | 赵正明 | Traditional Chinese medicine preparation for specially treating kidney neoplasms, kidney stone, renal cyst and hydronephrosis |
| CN106176925A (en) * | 2016-08-29 | 2016-12-07 | 凯里市新元药店 | A kind of Chinese medicine formula treating lithangiuria |
| CN107485630A (en) * | 2017-08-31 | 2017-12-19 | 朱虹旭 | A kind of Chinese medicine composition for treating lithiasis and its preparation and instructions of taking |
| CN108403974A (en) * | 2018-05-15 | 2018-08-17 | 陈忠 | A kind of Chinese medicine composition for treating calculus |
| CN108671098A (en) * | 2018-05-25 | 2018-10-19 | 蒙开科 | A kind of calculus eliminating pill and preparation method thereof |
| CN109091512A (en) * | 2018-09-26 | 2018-12-28 | 袁铁华 | A kind of drug and preparation method thereof for treating calculus |
| CN109700851A (en) * | 2019-02-19 | 2019-05-03 | 靳川宝 | A kind of Chinese medicine composition and preparation method thereof for treating lithiasis |
| CN111135234A (en) * | 2020-01-16 | 2020-05-12 | 刘侠 | Traditional Chinese medicine composition for treating calculus |
| CN111821338A (en) * | 2019-04-18 | 2020-10-27 | 张祥君 | Oral liquid for treating calculus and preparation method thereof |
| CN112245539A (en) * | 2020-11-20 | 2021-01-22 | 刘雄超 | Traditional Chinese medicine composition for treating canine/feline vesical calculus and idiopathic cystitis and preparation method thereof |
-
2009
- 2009-03-10 CN CNA2009100739120A patent/CN101491572A/en active Pending
Cited By (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102861134A (en) * | 2012-09-09 | 2013-01-09 | 王人杰 | Six-ingredient litholytic powder |
| CN103006895A (en) * | 2012-11-26 | 2013-04-03 | 李延 | Preparation of lithontriptic capsule |
| CN103961635A (en) * | 2013-01-30 | 2014-08-06 | 蒋孝峰 | Traditional Chinese medicine for treating nephrolithiasis and gallstone |
| CN103212027A (en) * | 2013-04-08 | 2013-07-24 | 段玉婷 | Traditional Chinese medicine preparation for treating urinary calculus |
| CN103212027B (en) * | 2013-04-08 | 2015-01-28 | 段玉婷 | Traditional Chinese medicine preparation for treating urinary calculus |
| CN103386032A (en) * | 2013-06-27 | 2013-11-13 | 陶殿华 | Chinese medicine for assisting with treatment of urinary calculus |
| CN103386079A (en) * | 2013-06-27 | 2013-11-13 | 陶殿华 | Chinese medicine for assisting with treatment of gallstones and preparation method thereof |
| CN103705797A (en) * | 2013-12-17 | 2014-04-09 | 陈中元 | Drug for treating kidney stones |
| CN105326911A (en) * | 2014-08-11 | 2016-02-17 | 赵正明 | Traditional Chinese medicine preparation for specially treating kidney neoplasms, kidney stone, renal cyst and hydronephrosis |
| CN104324083A (en) * | 2014-10-30 | 2015-02-04 | 张立 | Pharmaceutical composition for treating kidney stones and preparation method of pharmaceutical composition |
| CN104398769A (en) * | 2014-11-29 | 2015-03-11 | 高春娟 | Medicament for treating lithangiuria and preparation method thereof |
| CN106176925A (en) * | 2016-08-29 | 2016-12-07 | 凯里市新元药店 | A kind of Chinese medicine formula treating lithangiuria |
| CN107485630A (en) * | 2017-08-31 | 2017-12-19 | 朱虹旭 | A kind of Chinese medicine composition for treating lithiasis and its preparation and instructions of taking |
| CN108403974A (en) * | 2018-05-15 | 2018-08-17 | 陈忠 | A kind of Chinese medicine composition for treating calculus |
| CN108403974B (en) * | 2018-05-15 | 2021-02-26 | 陈忠 | Traditional Chinese medicine composition for treating calculus |
| CN108671098A (en) * | 2018-05-25 | 2018-10-19 | 蒙开科 | A kind of calculus eliminating pill and preparation method thereof |
| CN109091512A (en) * | 2018-09-26 | 2018-12-28 | 袁铁华 | A kind of drug and preparation method thereof for treating calculus |
| CN109700851A (en) * | 2019-02-19 | 2019-05-03 | 靳川宝 | A kind of Chinese medicine composition and preparation method thereof for treating lithiasis |
| CN111821338A (en) * | 2019-04-18 | 2020-10-27 | 张祥君 | Oral liquid for treating calculus and preparation method thereof |
| CN111135234A (en) * | 2020-01-16 | 2020-05-12 | 刘侠 | Traditional Chinese medicine composition for treating calculus |
| CN112245539A (en) * | 2020-11-20 | 2021-01-22 | 刘雄超 | Traditional Chinese medicine composition for treating canine/feline vesical calculus and idiopathic cystitis and preparation method thereof |
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Open date: 20090729 |