CN101449968B - Method and device for in-phase measurement of near infrared brain function detector - Google Patents

Method and device for in-phase measurement of near infrared brain function detector Download PDF

Info

Publication number
CN101449968B
CN101449968B CN200810306739XA CN200810306739A CN101449968B CN 101449968 B CN101449968 B CN 101449968B CN 200810306739X A CN200810306739X A CN 200810306739XA CN 200810306739 A CN200810306739 A CN 200810306739A CN 101449968 B CN101449968 B CN 101449968B
Authority
CN
China
Prior art keywords
signal
brain function
infrared brain
detecting instrument
synchronous
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN200810306739XA
Other languages
Chinese (zh)
Other versions
CN101449968A (en
Inventor
骆清铭
龚辉
李婷
吕晓华
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Huazhong University of Science and Technology
Original Assignee
Huazhong University of Science and Technology
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Huazhong University of Science and Technology filed Critical Huazhong University of Science and Technology
Priority to CN200810306739XA priority Critical patent/CN101449968B/en
Publication of CN101449968A publication Critical patent/CN101449968A/en
Application granted granted Critical
Publication of CN101449968B publication Critical patent/CN101449968B/en
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Landscapes

  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)

Abstract

The invention relates to a method and device for implementing measurement synchronization of near-infrared brain function detector. The device comprises a near-infrared brain function detector and at least one medical instrument with the exception of the near-infrared brain function detector, also comprises a control signal generating device and a control signal transmission module; the control signal generating module generates a synchronous starting measurement signal and a synchronous closing measurement signal; the control signal transmission module transmits the signal in shunt to the medical instrument and the near-infrared brain function detector; the near-infrared brain function detector is provided with a signal capturing module for capturing the signal, a synchronous starting data acquisition module and a synchronous closing data acquisition module, after capturing the signal, the synchronous starting data acquisition module and the synchronous closing data acquisition module respectively control the near-infrared brain function detector to start measurement and interrupt or stop measurement. The invention can enable the near-infrared brain function detector to perform multiple-mode measurement with other instruments synchronously, without changing the other instruments.

Description

A kind of method and apparatus of realizing Near-infrared Brain function detecting instrument measurement synchronization
Technical field
The present invention relates to biomedical engineering field, relate in particular to a kind of method and apparatus of realizing Near-infrared Brain function detecting instrument measurement synchronization.
Background technology
With respect to widely used brain function detection technique---function nmr imaging technique (fMRI), positron emission tomography (PET), electroencephalogram/event related potential technology (EEG/ERP), emerging Near-infrared Brain function spectrometry or imaging (NIRS/fNIRI) have can be portable, cheap, the temporal resolution height, advantages such as Noninvasive detection have obtained favorable comment more and more widely in brain research and Clinical detection.NIRS is a Near-infrared Brain function spectrometry, and fNIRI is a Near-infrared Brain functional imaging instrument, and the Near-infrared Brain function detecting instrument among the present invention comprises both, represents with NIRS/fNIRI.
Along with to the raising of disease of brain diagnostic analysis demand and going deep into of global brain science research, in the cerebration process, obtain different physiological parameters simultaneously and carry out analysis-by-synthesis, become the important trend of cerebral function imaging technical development.Therefore, present stage is badly in need of the multi-mode cerebral function imaging technology of the integrated NIRS/fNIRI of development and other prior aries, realizes the synchro measure of NIRS/fNIRI and prior art.
Because other medicine detector that the user generally uses, as fMRI, PET, EEG/ERP, ultra sonic imaging and physiological multi-parameter monitor mainly is business-like monomer type, is not suitable for that these instruments are carried out software or hardware modifications or interpolation function and realizes combining with NIRS/fNIRI.To further promote the use of NIRS/fNIRI, and the multi-mode measurement that realizes comprising NIRS/fNIRI, needing to set up does not have the simultaneous techniques scheme that technology is changed to other existing instrument except NIRS/fNIRI.
(publication number: CN 1879564A) combination of measurements of having introduced two instruments is presented at a technical scheme on the display in patent application " integrated anesthesia monitoring and ultrasonic demonstration ", but only simply point out in an embodiment to utilize a synchronizing signal to make the internal clocking of each instrument synchronous, do not specify the problem that solves synchronous detecting by any way.About many device synchronization, authorized or disclosed relevant patent or patent application (ZL 01130178.3; CN 1406429A; CN101150316A; CN 1874191A) all adopts the general thinking of developing synchronized measurement system, master-slave equipment promptly is set, main equipment produces one or more signals of control all devices, and slave unit receives the signal of autonomous device, and realizes synchronously by the adjustment to each device interior clock of principal and subordinate.This class methods more complicated need be implemented the master or from control, need carry out the technology change to each system implementation hardware and software each equipment.
Summary of the invention
In order to solve above-mentioned technical problem, a kind of method and apparatus of realizing Near-infrared Brain function detecting instrument (NIRS/fNIRI) measurement synchronization is provided, its purpose is, realize that Near-infrared Brain function detecting instrument and other instruments carry out multi-mode synchronously and measure, and other instruments are not applied any technology change.
The invention provides a kind of device of realizing Near-infrared Brain function detecting instrument measurement synchronization, comprise the Near-infrared Brain function detecting instrument, and at least one Medical Instruments except that the Near-infrared Brain function detecting instrument, also comprise control signal generation module and control signal transport module;
Be provided with in the Near-infrared Brain function detecting instrument: synchronous log-on data acquisition module, stop data acquisition module synchronously, and the signal capture module;
The control signal generation module is used for producing synchronous starting measurement signal when the Near-infrared Brain function detecting instrument need begin to measure, and produces synchronous closing measurement signal when the Near-infrared Brain function detecting instrument need interrupt or stop measuring;
The control signal transport module is used for synchronous starting measurement signal or synchronous closing measurement signal are transferred to described Medical Instruments and Near-infrared Brain function detecting instrument along separate routes;
The signal capture module is used to catch synchronous starting measurement signal or synchronous closing measurement signal;
The log-on data acquisition module is used for after the signal capture module is caught synchronous starting measurement signal synchronously, and control Near-infrared Brain function detecting instrument begins to measure;
The end data acquisition module is used for after the signal capture module is caught synchronous closing measurement signal synchronously, and control Near-infrared Brain function detecting instrument interrupts or stops measuring;
Described Medical Instruments also is used for after receiving synchronous starting measurement signal, stamps to begin sign or enable external trigger to start measurement function on the data of gathering in real time; Perhaps after receiving synchronous closing measurement signal, on the data of gathering in real time, stamp and finish sign or enable external trigger to interrupt measurement function.
Synchronous starting measurement signal and synchronous closing measurement signal are the folk prescription wave pulse signal.
The control signal generation module has first output port and second output port; First output port is used to export synchronous starting measurement signal, and second output port is used to export synchronous closing measurement signal.
The signal capture module has first capture-port and second capture-port; First capture-port is used to catch synchronous starting measurement signal, and second capture-port is used to catch synchronous closing measurement signal.
The control signal transport module comprises three-phase or heterogeneous interface, and the control signal transport tape that is connected with this interface; Wherein three-phase or heterogeneous interface are connected with control signal generation module and described Medical Instruments, and the control signal transport tape also is connected with the signal capture module.
The control signal transport tape is at least 4 passages, be used to guarantee that first output port is connected with first capture-port, second output port is connected with second capture-port, the power supply signal of control signal generation module is connected with the power supply signal of signal capture module, and the earth signal of control signal generation module is connected with the earth signal of signal capture module.
The folk prescription wave pulse signal is the maximum sampling interval of width greater than Near-infrared Brain function detecting instrument and described Medical Instruments.
The high level amplitude of folk prescription wave pulse signal is greater than 3.7 volts and be less than or equal to 5 volts.
When the Near-infrared Brain function detecting instrument begins to measure, log-on data collection and data show two-wire journey, and the control at startup interface; When interruption of Near-infrared Brain function detecting instrument or termination are measured, suspend data acquisition and data show two-wire journey.
Described Medical Instruments is also encoded to synchronous starting measurement signal or synchronous closing measurement signal after receiving synchronous starting measurement signal or synchronous closing measurement signal.
The instrument that described infrared brain function detector is Near-infrared Brain function spectrometry or Near-infrared Brain functional imaging.
Described Medical Instruments is EEG/ERP instrument, fMRI instrument or PET instrument.
The invention provides a kind of method that said apparatus is realized Near-infrared Brain function detecting instrument measurement synchronization of using, comprising:
Step 10, the control signal generation module produces synchronous starting measurement signal, and synchronous starting measurement signal is transferred to the Near-infrared Brain function detecting instrument along separate routes, and at least one Medical Instruments except that the Near-infrared Brain function detecting instrument;
Step 20, described Medical Instruments are stamped on the data of gathering in real time and are begun sign or enable external trigger to start measurement function; The signal capture module is caught synchronous starting measurement signal, and the Near-infrared Brain of log-on data acquisition module control synchronously function detecting instrument begins to measure;
Step 30, the control signal generation module produces synchronous closing measurement signal, and this synchronous closing measurement signal is transferred to Near-infrared Brain function detecting instrument and described Medical Instruments along separate routes;
Step 40, described Medical Instruments are stamped on the data of gathering in real time and are finished sign or enable external trigger to interrupt measurement function; The signal capture module is caught synchronous closing measurement signal, and the Near-infrared Brain of log-on data acquisition module control synchronously function detecting instrument interrupts or stops measuring.
Synchronous starting measurement signal and synchronous closing measurement signal are the folk prescription wave pulse signal.
In the step 20, when the Near-infrared Brain function detecting instrument begins to measure, log-on data collection and data show two-wire journey, and the control at startup interface; In the step 40, when interruption of Near-infrared Brain function detecting instrument or termination are measured, suspend data acquisition and data show two-wire journey.
In the step 20, described Medical Instruments is also encoded to synchronous starting measurement signal after receiving synchronous starting measurement signal; In the step 40, described Medical Instruments is also encoded to synchronous closing measurement signal after receiving synchronous closing measurement signal.
The instrument that described infrared brain function detector is Near-infrared Brain function spectrometry or Near-infrared Brain functional imaging.
The present invention adopts the outer control signal that begins synchronously and finish that produces, and shunt is transferred to other instruments and Near-infrared Brain function detecting instrument, control the startup and the termination of Near-infrared Brain function detecting instrument image data on the one hand, utilizing other instruments maybe can be provided with by external trigger the mark of external digital signal real time data on the other hand starts and the function that stops data acquisition, make other instruments automatically to the data mark and the external trigger startup/termination data acquisition of real-time measurement, thereby the data sequence that makes data sequence or be triggered between the mark gather is overlapping on Measuring Time with the data sequence of Near-infrared Brain function detecting instrument detection.The present invention does not implement the change of any hardware or software to other instruments, can either make the user be easy to accept, and can make the user avoid losing the economic loss of other instruments manufacturer free repair guarantee service again.
The present invention at most only needs to produce signal generator, three/heterogeneous interface, control signal transmission line, the square-wave pulse acquisition equipment of synchronous control signal at hardware aspect.Wherein, signal generator can use PC to replace, and only can write out setting width high level signal to the computer numeral port and gets final product with corresponding; When the capture card of Near-infrared Brain function detecting instrument contained at least two switching value input ports, most of capture cards all satisfied this situation, also can omit the square-wave pulse acquisition equipment.Because interface and transmission line (being winding displacement) all are dog-cheap components and parts, the device hardware components cost that the present invention relates to is very low.In addition, the connection of these hardware is very simple.The software aspect is only used to Near-infrared Brain function detecting instrument acquisition software relevant position two modules of interpolation to get final product, and is simple to operate.
Among the present invention, will check that whether the different port of setting receives high level signal, simplifies the identification of control signal, and has improved discrimination to being converted to of control signal; Produce the control signal module be provided with the high level width greater than all by the sampling interval of synchronized instruments, guaranteed that all appts all can collect this control signal at this section according to sample rate separately in the period, avoided being identified as low level by mistake and can't realize that external trigger starts or the time-out data acquisition, improved stability.
Response time of the present invention is short.Because the transmission path of signal is no more than 100 meters usually, thus its transmission time can ignore, so response time less than transmission time of control signal and control signal high level time domain width with.
Description of drawings
Fig. 1 is Near-infrared Brain function detecting instrument provided by the invention is realized the multi-mode measurement synchronization in conjunction with other instruments a device sketch map;
Fig. 2 a and Fig. 2 b are synchronous startup provided by the invention and the control flow chart that stops Near-infrared Brain function detecting instrument data acquisition module;
Fig. 3 is a preferred embodiment, promptly stimulates the synchronous Near-infrared Brain function detecting instrument of normal form and the installation drawing of EEG/ERP detector synchronous detecting with audiovisual.
Fig. 4 a and Fig. 4 b are the synchronous startup of above preferred embodiment and the control flow chart that stops Near-infrared Brain function detecting instrument data acquisition module;
Fig. 5 is Near-infrared Brain function detecting instrument provided by the invention is realized the multi-mode measurement synchronization in conjunction with other instruments a method sketch map.
The specific embodiment
The device that Near-infrared Brain function detecting instrument provided by the invention is realized the multi-mode measurement synchronization in conjunction with other instruments as shown in Figure 1.This device comprises need be by other synchronous instruments 1 (for example fMRI instrument, PET instrument or EEG/ERP instrument), Near-infrared Brain function detecting instrument 2, control signal generation module 3, be loaded into the synchronous log-on data acquisition module 4 in the Near-infrared Brain function detecting instrument 2 and stop data acquisition module 5 synchronously, the transport module 6 of control signal, and square-wave pulse signal trapping module 7;
Control signal generation module 3 is used for producing respectively the folk prescription wave pulse signal that control begins to measure synchronously and measure with EOS, and the output port of two signals is called after P1 and P2 successively;
The transport module 6 of control signal, be used for control signal is transferred to other instruments and square-wave pulse acquisition equipment along separate routes, it comprises three-phase or the heterogeneous interface 6.1 and the control signal transport tape 6.2 that is connected with this interface that is connected with control signal generation module 3 and other instrument;
Square-wave pulse signal trapping module 7, it links to each other with control signal transport tape 6.2, is used to catch the folk prescription wave pulse signal that begins synchronously to measure and measure with EOS, the capture-port called after O1 and the O2 of two signals.
Control signal transport tape 6.2 is at least 4 passages in the said apparatus, guarantee that P1 is connected with O1, P2 is connected with O2, and control signal generation module 3 is connected with the power supply signal of square-wave pulse signal trapping module 77, and control signal generation module 3 is connected with the earth signal of square-wave pulse signal trapping module 77.
The folk prescription wave pulse signal that control signal generation module 3 produces in the said apparatus is the maximum sampling interval of width greater than synchronous all appts; The high level amplitude smaller or equal to and as far as possible near 5 volts, and greater than 3.7 volts.The preferred implementation of this module comprises that using signal generator or use interface to control software exports switching value signal to certain digital port of computer.
Wherein, start the control flow of Near-infrared Brain Function detection device data acquisition synchronously and stop the data acquisition of Near-infrared Brain Function detection device synchronously, shown in Fig. 2 a and Fig. 2 b.Log-on data acquisition module 4 starts after request beginning image data synchronously, at first visit the port of the corresponding O1 of capture card, gather the signal of this port then, if high level, with this port assignment 0, log-on data collection and data show two-wire journey then, and start the control at interface, if low level, the port of the corresponding O1 of backward reference capture card; Stop data acquisition module 5 synchronously in the data acquisition thread, when carrying out new round sampling to data, each request starts, at first visit the port of the corresponding O2 of corresponding capture card, gather the signal of this port then, if high level then suspends data acquisition and data show two-wire journey, if low level, then still to this port assignment 0, and start sampling to the next round data.
One each passage of taking turns sampled representation Near-infrared Brain function detecting instrument has all collected data, each is taken turns and all will visit the O2 port before the sampling and whether receive control signal, so that in time control stops data acquisition, can guarantee that like this control response that stops synchronously is very fast.Certainly, log-on data acquisition module and synchronous termination data acquisition module are in the state of work always synchronously, should also can realize the present invention.
Near-infrared Brain function detecting instrument provided by the invention as shown in Figure 5, comprising in conjunction with the method for other instruments realization multi-mode measurement synchronization:
Step 51 at first produces the folk prescription wave pulse signal that user's control begins to measure synchronously, and this signal is transferred to other instruments and Near-infrared Brain function detecting instrument along separate routes;
Step 52, other instruments are encoded to this signal automatically and are stamped on the data of gathering in real time and begin sign or enable external trigger to start measurement function; Near-infrared Brain function detecting instrument user wave impulse acquisition equipment receives this signal, in case after catching this signal, the Near-infrared Brain of log-on data acquisition module control synchronously function detecting instrument starts to be measured;
Step 53 produces the folk prescription wave pulse signal that user's control is measured with EOS then, equally this signal is divided multiplexing to give other instruments and Near-infrared Brain function detecting instrument;
Step 54, other instruments are encoded to this signal automatically and are stamped on the data of gathering in real time and finish sign or enable external trigger interruption measurement function; Infrared brain function detector user wave impulse acquisition equipment receives this signal, in case after catching this signal, stop data acquisition module control Near-infrared Brain function detecting instrument synchronously and interrupt or the termination measurement.
Like this, other instruments measured by external trigger or sign between the data of data sequence and Near-infrared Brain function detecting instrument measurement overlapping in time, reach the purpose of synchro measure.
Wherein, the folk prescription wave pulse signal requires the maximum sampling interval of its pulse width greater than synchronous all appts; The high level amplitude smaller or equal to and as far as possible near 5 volts, and greater than 3.7 volts.There are not the master-slave equipment relation in other instruments and Near-infrared Brain function detecting instrument in this method, need not carry out communication contact between two equipment or implement control.
Further set forth the present invention below by a preferred embodiment.
Use the present invention to realize synchronous detecting to obtain examined people at the example of accepting audiovisual and stimulate normal form process midbrain activity change to the EEG/ERP system of the Near-infrared Brain functional imaging instrument that stimulates the period cerebration and Neuroscan company.Among this embodiment, stimulation presents program writes out on the Presentation software platform, and this software platform provides the function of the digit order number output switching value signal of code control computer parallel port; But used Near-infrared Brain functional imaging instrument with capture card contain a plurality of ports of receiving key amount input signal.
The synchronous method of this embodiment is: at first add in this stimulation normal form program and provide a switching value signal that begins data acquisition synchronously when code is feasible to begin to present first stimulation, and this signal is transferred to EEG/ERP instrument and Near-infrared Brain function detecting instrument along separate routes, this signal makes EEG/ERP stamp beginning label automatically on the data of always gathering in real time on the one hand, catch via the capture card switching value input port of Near-infrared Brain functional imaging instrument on the other hand, control the data acquisition of Near-infrared Brain functional imaging device then and start synchronously; Provide an end signal in the moment that has presented last stimulation, and this signal is transferred to EEG/ERP instrument and Near-infrared Brain function detecting instrument along separate routes, this signal makes EEG/ERP stamp end mark automatically on the data of always gathering in real time on the one hand, catch via the capture card switching value input port of Near-infrared Brain functional imaging instrument on the other hand, and control Near-infrared Brain functional imaging instrument stops synchronously.
The synchronous measuring apparatus of this embodiment, except by synchronous EEG/ERP instrument 8 and Near-infrared Brain function detecting instrument 2, also comprise control signal generation module 3, control signal transport module 6 and synchronous Near-infrared Brain Function detection device data acquisition module 4 and the synchronous Near-infrared Brain Function detection device data acquisition module 5 that stops of starting.Control signal generation module 3 is loaded in the stimulation programs 9 on the Presentation software platform.Wherein:
Control signal generation module 3 is used to produce commencing signal and the end signal that control data is gathered; The commencing signal and the end signal of this module output are the digital signal of folk prescription wave impulse, but have different high level digit order numbers.Narrate below convenient, the life commencing signal high level digit order number corresponding port different with end signal is followed successively by P1 and P2.The high level width of control signal needs the data sampling interval maximum greater than Near-infrared Brain function detecting instrument and other detectors.The commencing signal and the end signal of this module output carry out real-time mark to the data of other instrument collections, perhaps trigger the startup in real time of other instruments or stop data acquisition.
The transport module 6 of control signal comprises three-phase or the heterogeneous interface 6.1 of exporting control signal, is used for the output control signal is transferred to other instruments and control signal transport tape along separate routes; Comprise three interfaces 6.3 that receive control signal, be used for control signal is inserted the capture card of Near-infrared Brain Function detection device; Also comprise the control signal transport tape 6.2 that connects two interfaces.The interface of the capture card of Near-infrared Brain function detecting instrument 2 is provided with and controls two ports that the Near-infrared Brain function detecting instrument starts and stop data acquisition respectively, narrates below convenient, successively called after O1 and O2.
Control signal transport tape 6.2 links to each other with O1 to the port P1 of above-mentioned two interfaces of major general, and port P2 links to each other with O2, and power supply links to each other respectively with the earth signal port.
Log-on data acquisition module 4 loads in the startup function of Near-infrared Brain function detecting instrument software kit synchronously, be used for gathering in real time the signal of O1 port, when returning during for low level, the signal that collects continues to gather this port signal, up to when the O1 port is high level signal, starts the data sampling of Near-infrared Brain function detecting instrument and show thread etc. in real time;
Termination data acquisition module 5 loads in the sampling thread startup function of Near-infrared Brain function detecting instrument software kit synchronously, be used for gathering in real time the signal of O2 port, when the signal that collects returns during for low level, start the next round data sampling, when the signal that collects is high level, then suspend the execution of data acquisition, demonstration and other inter-related task;
Control signal is the folk prescription ripple, and the high level width is provided with the sampling interval greater than Near-infrared Brain functional imaging instrument, less than stimulus intervals.Near-infrared Brain functional imaging instrument is to the reception of commencing signal and end signal and implement synchronous control flow shown in Fig. 4 a and Fig. 4 b, is to implement the control that starts or stop synchronously by looking for the signal value of the corresponding switching value input port of acquisition port with a last embodiment difference.This embodiment has not only solved the synchronous detecting of Near-infrared Brain functional imaging instrument and EEG/ERP, and equal overlapping on time dimension of the data segment of having realized stimulating data segment and the detection of Near-infrared Brain functional imaging instrument between the sign that normal form, EEG/ERP beat, its error is less than the sampling interval of Near-infrared Brain functional imaging instrument.
Those skilled in the art can also carry out various modifications to above content under the condition that does not break away from the definite the spirit and scope of the present invention of claims.Therefore scope of the present invention is not limited in above explanation, but determine by the scope of claims.

Claims (13)

1. device of realizing Near-infrared Brain function detecting instrument measurement synchronization, comprise the Near-infrared Brain function detecting instrument, and at least one Medical Instruments except that the Near-infrared Brain function detecting instrument, it is characterized in that, also comprise control signal generation module and control signal transport module;
Be provided with in the Near-infrared Brain function detecting instrument: synchronous log-on data acquisition module, stop data acquisition module synchronously, and the signal capture module;
The control signal generation module is used for producing synchronous starting measurement signal when the Near-infrared Brain function detecting instrument need begin to measure, and produces synchronous closing measurement signal when the Near-infrared Brain function detecting instrument need interrupt or stop measuring;
The control signal transport module is used for synchronous starting measurement signal or synchronous closing measurement signal are transferred to described Medical Instruments and Near-infrared Brain function detecting instrument along separate routes;
The signal capture module is used to catch synchronous starting measurement signal or synchronous closing measurement signal;
The log-on data acquisition module is used for after the signal capture module is caught synchronous starting measurement signal synchronously, and control Near-infrared Brain function detecting instrument begins to measure;
Stop data acquisition module synchronously, be used for after the signal capture module is caught synchronous closing measurement signal, control Near-infrared Brain function detecting instrument interrupts or stops measuring;
Described Medical Instruments also is used for after receiving synchronous starting measurement signal, stamps to begin sign or enable external trigger to start measurement function on the data of gathering in real time; Perhaps after receiving synchronous closing measurement signal, on the data of gathering in real time, stamp and finish sign or enable external trigger to interrupt measurement function;
Described control signal generation module has first output port and second output port; First output port is used to export synchronous starting measurement signal, and second output port is used to export synchronous closing measurement signal;
Described signal capture module has first capture-port and second capture-port; First capture-port is used to catch synchronous starting measurement signal, and second capture-port is used to catch synchronous closing measurement signal;
Described control signal transport module comprises heterogeneous interface, and the control signal transport tape that is connected with this interface; Wherein heterogeneous interface is connected with control signal generation module and described Medical Instruments, and the control signal transport tape also is connected with the signal capture module;
Described control signal transport tape is at least 4 passages, be used to guarantee that first output port is connected with first capture-port, second output port is connected with second capture-port, the power supply signal of control signal generation module is connected with the power supply signal of signal capture module, and the earth signal of control signal generation module is connected with the earth signal of signal capture module.
2. the device of realization Near-infrared Brain function detecting instrument measurement synchronization as claimed in claim 1 is characterized in that synchronous starting measurement signal and synchronous closing measurement signal are the folk prescription wave pulse signal.
3. the device of realization Near-infrared Brain function detecting instrument measurement synchronization as claimed in claim 2 is characterized in that the width of folk prescription wave pulse signal is greater than the maximum sampling interval of Near-infrared Brain function detecting instrument and described Medical Instruments.
4. the device of realization Near-infrared Brain function detecting instrument measurement synchronization as claimed in claim 2 is characterized in that, the high level amplitude of folk prescription wave pulse signal is greater than 3.7 volts and be less than or equal to 5 volts.
5. the device of realization Near-infrared Brain function detecting instrument measurement synchronization as claimed in claim 2 is characterized in that, when the Near-infrared Brain function detecting instrument begins to measure, and log-on data collection and data show two-wire journey, and the control at startup interface; When interruption of Near-infrared Brain function detecting instrument or termination are measured, suspend data acquisition and data show two-wire journey.
6. the device of realization Near-infrared Brain function detecting instrument measurement synchronization as claimed in claim 1, it is characterized in that, described Medical Instruments is also encoded to synchronous starting measurement signal or synchronous closing measurement signal after receiving synchronous starting measurement signal or synchronous closing measurement signal.
7. the device of realization Near-infrared Brain function detecting instrument measurement synchronization as claimed in claim 1 is characterized in that described Near-infrared Brain function detecting instrument is the instrument of Near-infrared Brain function spectrometry or Near-infrared Brain functional imaging.
8. the device of realization Near-infrared Brain function detecting instrument measurement synchronization as claimed in claim 2 is characterized in that, described Medical Instruments is EEG/ERP instrument, fMRI instrument or PET instrument.
9. a device that utilizes realization Near-infrared Brain function detecting instrument measurement synchronization as claimed in claim 1 is realized the method for Near-infrared Brain function detecting instrument measurement synchronization, it is characterized in that, comprising:
Step 10, the control signal generation module produces synchronous starting measurement signal, and synchronous starting measurement signal is transferred to the Near-infrared Brain function detecting instrument along separate routes, and described Medical Instruments;
Step 20, described Medical Instruments are stamped on the data of gathering in real time and are begun sign or enable external trigger to start measurement function; The signal capture module is caught synchronous starting measurement signal, and the Near-infrared Brain of log-on data acquisition module control synchronously function detecting instrument begins to measure;
Step 30, the control signal generation module produces synchronous closing measurement signal, and this synchronous closing measurement signal is transferred to Near-infrared Brain function detecting instrument and described Medical Instruments along separate routes;
Step 40, described Medical Instruments are stamped on the data of gathering in real time and are finished sign or enable external trigger to interrupt measurement function; The signal capture module is caught synchronous closing measurement signal, stops data acquisition module control Near-infrared Brain function detecting instrument synchronously and interrupts or the termination measurement.
10. method as claimed in claim 9 is characterized in that synchronous starting measurement signal and synchronous closing measurement signal are the folk prescription wave pulse signal.
11. method as claimed in claim 9 is characterized in that, in the step 20, and when the Near-infrared Brain function detecting instrument begins to measure, log-on data collection and data show two-wire journey, and the control at startup interface; In the step 40, when interruption of Near-infrared Brain function detecting instrument or termination are measured, suspend data acquisition and data show two-wire journey.
12. method as claimed in claim 9 is characterized in that, in the step 20, described Medical Instruments is also encoded to synchronous starting measurement signal after receiving synchronous starting measurement signal; In the step 40, described Medical Instruments is also encoded to synchronous closing measurement signal after receiving synchronous closing measurement signal.
13. method as claimed in claim 9 is characterized in that, described Near-infrared Brain function detecting instrument is the instrument of Near-infrared Brain function spectrometry or Near-infrared Brain functional imaging.
CN200810306739XA 2008-12-31 2008-12-31 Method and device for in-phase measurement of near infrared brain function detector Expired - Fee Related CN101449968B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN200810306739XA CN101449968B (en) 2008-12-31 2008-12-31 Method and device for in-phase measurement of near infrared brain function detector

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN200810306739XA CN101449968B (en) 2008-12-31 2008-12-31 Method and device for in-phase measurement of near infrared brain function detector

Publications (2)

Publication Number Publication Date
CN101449968A CN101449968A (en) 2009-06-10
CN101449968B true CN101449968B (en) 2011-05-25

Family

ID=40732580

Family Applications (1)

Application Number Title Priority Date Filing Date
CN200810306739XA Expired - Fee Related CN101449968B (en) 2008-12-31 2008-12-31 Method and device for in-phase measurement of near infrared brain function detector

Country Status (1)

Country Link
CN (1) CN101449968B (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102512142B (en) * 2011-12-22 2013-10-23 哈尔滨工业大学 Recursive least squares adaptive-filtering near-infrared brain function signal extraction method based on multi-distance measurement method
CN105573844B (en) * 2014-10-13 2019-04-26 联想(北京)有限公司 A kind of control method and electronic equipment
US10799161B2 (en) * 2016-04-04 2020-10-13 Technische Universität Berlin Biosignal acquisition device and system, method for acquisition of biosignals
CN106236085B (en) * 2016-09-26 2019-03-08 中国医学科学院生物医学工程研究所 For detecting the generating device and detection method of NEG cerebration instrument synchronism
CN110433397A (en) * 2019-08-20 2019-11-12 国家康复辅具研究中心 A kind of the dynamic brain function detection method and system synchronous with transcranial magnetic stimulation
CN112890823B (en) * 2021-01-22 2023-10-13 深圳市润谊泰益科技有限责任公司 Physiological data acquisition method, system and storage medium
CN115844325A (en) * 2022-11-17 2023-03-28 天津大学 Distributed fNIRS brain function imaging system for super-scanning application

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1799497A (en) * 2005-11-26 2006-07-12 安徽君诚体育器材有限公司 electromyographic signal collection and action form synchronization method
CN1852681A (en) * 2003-09-19 2006-10-25 株式会社日立医药 Organism information signal processing system comprising combination of organism light measuring device and brain wave measuring device, and probe used for same
CN101088465A (en) * 2006-09-27 2007-12-19 北京航空航天大学 Three-dimensional type-B ultrasonic diagnostic apparatus based on stereoscopic vision
CN201341869Y (en) * 2008-12-31 2009-11-11 华中科技大学 Device realizing measurement synchronization of near-infrared brain function detector

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1852681A (en) * 2003-09-19 2006-10-25 株式会社日立医药 Organism information signal processing system comprising combination of organism light measuring device and brain wave measuring device, and probe used for same
CN1799497A (en) * 2005-11-26 2006-07-12 安徽君诚体育器材有限公司 electromyographic signal collection and action form synchronization method
CN101088465A (en) * 2006-09-27 2007-12-19 北京航空航天大学 Three-dimensional type-B ultrasonic diagnostic apparatus based on stereoscopic vision
CN201341869Y (en) * 2008-12-31 2009-11-11 华中科技大学 Device realizing measurement synchronization of near-infrared brain function detector

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
JP特开2006-289565A 2006.10.26

Also Published As

Publication number Publication date
CN101449968A (en) 2009-06-10

Similar Documents

Publication Publication Date Title
CN101449968B (en) Method and device for in-phase measurement of near infrared brain function detector
CN201341869Y (en) Device realizing measurement synchronization of near-infrared brain function detector
CN203153118U (en) Household multifunctional health detection sofa
CN202776284U (en) Portable multi-parameter checking all-in-one machine
CN204971277U (en) Can realize health service robot of brain electric -examination survey
CN105078450A (en) Health service robot capable of achieving electroencephalogram detection
CN101385641A (en) Wave analysis method and device of physiological parameter
CN201814575U (en) Multifunctional diagnosis and treatment integrated system
CN103279665A (en) Multi-user and multi-parameter wireless detection, diagnosis, service and monitoring method
CN102591996B (en) Data synchronization architecture and method for multiple measurement instruments
Kozlovszky et al. Cardiovascular and diabetes focused remote patient monitoring
CN107595255A (en) A kind of pulse condition checkout and diagnosis portable unit of accurate simulation TCM pulse diagnosis process
CN109222994A (en) Oxygen saturation monitor display methods and custodial care facility
CN101461707B (en) Multichannel/multimachine synchronous control system and method of near-infrared medicinal detector
CN102579021A (en) System and method for measuring pulse blood oxygen
WO2021154850A1 (en) Glucose monitoring system
WO2016061767A1 (en) Continuous glucose monitoring system and monitoring terminal
CN202136338U (en) Electronic interactive sand table device
CN103705226A (en) Sphygmomanometer with blood pressure evaluation function
CN102940484B (en) Household cardiovascular detecting and diagnosing device capable of performing telecommunication
KR101338352B1 (en) Display Method for Bio-signal
CN205458660U (en) Electrocardio monitor
CN204133466U (en) A kind of long distance wireless collaterals of human information acquisition system
CN201341873Y (en) Multi-channel multi-machine synchronous control system for near-infrared medical detecting instrument
Andriţoi et al. An portable device for ECG and photoplethysmographic signal acquisition

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C14 Grant of patent or utility model
GR01 Patent grant
CP02 Change in the address of a patent holder
CP02 Change in the address of a patent holder

Address after: 430074 Hubei Province, Wuhan city Hongshan District Luoyu Road No. 1037

Patentee after: Huazhong University of Science and Technology

Address before: 430074 1037 Luo Yu Road, Hongshan District, Wuhan, Hubei.

Patentee before: Huazhong University of Science and Technology

CF01 Termination of patent right due to non-payment of annual fee
CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20110525

Termination date: 20201231