CN101444472B - Skin care product - Google Patents

Skin care product Download PDF

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Publication number
CN101444472B
CN101444472B CN2008102193501A CN200810219350A CN101444472B CN 101444472 B CN101444472 B CN 101444472B CN 2008102193501 A CN2008102193501 A CN 2008102193501A CN 200810219350 A CN200810219350 A CN 200810219350A CN 101444472 B CN101444472 B CN 101444472B
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skin
skin care
keratin
care item
plant extract
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CN101444472A (en
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万岳鹏
陈保华
苏毅生
何益飞
宋晶晶
蒋青
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GUANGZHOU HOUDY GROUP CO Ltd
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GUANGZHOU HOUDY GROUP CO Ltd
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Abstract

The invention belongs to the skin care field and in particular relates to a skin care product which is added with medicinal plant extract and keratin. The skin care product is made from the components with the following weight percentage of 1-20% of the medicinal plant extract, 0.2-10% of the keratin, 5-15% of esters, 5-11% of oils, 1-4% of high fatty alcohol, 2-8% of emulsifier, 0.1-0.4% of carbomer, 0.1-0.4% of triethanolamine (99%), 0.1-1.0% of preservative and 0.1-1.0% of essence, and the rest is water. The medicinal plant extract added in the skin care product has the efficacies of promoting blood circulation, removing blood stasis, benefiting vital energy and strengthening essence, delays skin aging process, increases the skin smoothness and elasticity and has good antibacterial and antiphlogistic functions. The added keratin can promote the cell enlargement and the collagen synthesis, reduce skin fine cracks and wrinkles, keep skin moisture and strengthen the skin compactness and elasticity.

Description

A kind of skin care item
Technical field
The invention belongs to skin care field.
Background technology
Skin is the maximum organ of human body, 5%~15% of gross weight percentage of liveweight, and the gross area is 1.5~2 square metres, thickness is 0.5~4 millimeter because of people or different because of the position.Skin covers whole body, links to each other closely with other organ of human body, plays a part the protection human body and does not receive outside stimulus or injury.Skin has the barrier action of two aspects: prevent on the one hand moisture in the body, the losing of electrolyte and other materials; Stop the intrusion of extraneous harmful substance on the other hand.Keeping the stable of human internal environment, on physiology, playing important defencive function, skin is also participated in the metabolic process of human body simultaneously.If want to have healthy beautiful skin, except will forming healthy living habit, the maintenance work that also will properly protect especially for exposed skin at ordinary times, like face, cervical region, hands, arm etc., more will be concentrated one's attention on care.
With advancing age, skin receives the effect of ultraviolet and airborne pollutant, lacks nutrition easily, and then makes the skin dehydration, destroys the keratin of skin, causes pachylosis, follows the string.Airborne dust, toxic gas and harmful bacterium etc. all can damage skin, cause skin allergy, inflammation, aging, pigmentation easily.Be necessary to provide a kind of and can promote skin-nourishing, maintenance moisture of skin, the keratic skin care item of reparation damaged skin.
Summary of the invention
The present invention provides a kind of skin care item, especially provide a kind of can blood circulation promoting and blood stasis dispelling, the QI invigorating spermatogenesis, anti-inflammation promotes cell protein metabolism etc. to promote skin-nourishing, repairs skin, recovers the skin care item of its natural elasticity.
Skin care item according to the invention, the mass percent of its contained component and each component is following: medicinal plant extract 1%~20%, keratin 0.2%~10%; Esters 5%~15%, oils 5%~11%, high fatty alcohol class 1%~4%; Emulsifying agent 2%~8%, carbomer 0.1%~0.4%, triethanolamine (99%) 0.1%~0.4%; Antiseptic 0.1%~1.0%, essence 0.1%~1.0%, water surplus.
Medicinal plant extract according to the invention is that medicinal plants is pulverized, and under 50 ℃, normal pressure, is that extracting solution that extractant lixiviate or circulation extraction obtain concentrates and forms with ethanol or water, and medicinal plants is selected from one or more in the following material: Flos Lonicerae; Semen Ginkgo, Radix Codonopsis, Radix Angelicae Sinensis; Radix Scutellariae, Radix Ginseng, Poria; The Rhizoma Atractylodis Macrocephalae, Rhizoma Chuanxiong.Preferably, said medicinal plants is selected from least three kinds of above listed material.
More preferably, the component that contains in the said medicinal plants and the mass percent of each component are following: Flos Lonicerae 5~20%, Semen Ginkgo 10~20%; Radix Codonopsis 10~20%, Radix Angelicae Sinensis 15~30%, Radix Scutellariae 15~30%; Radix Ginseng 10~30%; Poria 10~20%, the Rhizoma Atractylodis Macrocephalae 10~20%, Rhizoma Chuanxiong 10~30%.
Keratin according to the invention is that animal hair is cleaned up, at organic base, in the TGA aqueous ammonium; At 60 ℃ of solubilizing reaction 2-8 hours, to filter, filtrating is with holding back quality 40-60kD dialysis bag; In mercaptoethanol 0.08% aqueous solution dialysis 30-50 hour, collect filtering residue; Filtrating is continued after the basic hydrolysis with holding back quality 3-4kD dialysis bag, and in mercaptoethanol 0.08% aqueous solution dialysis 40-60 hour, the collection filtering residue; Behind two kinds of filtering residue mix homogeneously, lyophilization obtains the white powder hydrolysis of keratin mixture that is mixed by quality 40000-60000 dalton and two kinds of keratin of quality 3000-4000 dalton.
Esters according to the invention is by at least a composition the in the following esters: caprylic/capric triglyceride, isopropyl myristate, pentaerythritol stearic acid ester 2 and tocopherol acetas.
Preferably, the composition of said esters and the percetage by weight of each component thereof are: caprylic/capric triglyceride 4-8%, isopropyl myristate 2-4%, pentaerythritol stearic acid ester 2 1-2%, tocopherol acetas 0.5-1%.
Oils according to the invention is to be selected from one or more of following material: C15-19 alkane, Butyrospermum Parkii Oil, polydimethylsiloxane.
The component of preferred oils and the percetage by weight of each component are: C15-19 alkane 3-6%, Butyrospermum Parkii Oil 1-2%, polydimethylsiloxane 1.5-3%.
High fatty alcohol class according to the invention is to be selected from one or more of following material: spermol, stearyl alcohol, cetearyl alcohol, isooctadecanol, behenyl alcohol.
Preferably, the percetage by weight of the component of said high fatty alcohol class and each component is: spermol 0.5-4%, stearyl alcohol 0.5-3%, cetearyl alcohol 0.5-4%, isooctadecanol 0.5-1%, behenyl alcohol 0.5-1%.
Emulsifying agent according to the invention be selected from following material one or more: glyceryl stearate, methyl glucose sesquistearate, PEG-20 methyl glucose sesquistearate, laureth-7/C13-14 alkane/polyacrylamide.
Preferably; The component of said emulsifying agent and the percetage by weight of each component are: glyceryl stearate 0.5-1%; Methyl glucose sesquistearate 0.8-1.6%, PEG-20 methyl glucose sesquistearate 1.2-2.4%, laureth-7/C13-14 alkane/polyacrylamide 0.5-3%.
Skin care item of the present invention, antiseptic that it is contained and essence can be skin care field conventional antiseptic and essence kind, as using antiseptic always: parabens, phenoxyethanol, benzoic acid/benzyl alcohol and derivant etc.; Essence commonly used: Fruity type, floral type, Radix Aucklandiae type, Chinese herbal medicine odor type etc., its consumption also can suitably be adjusted according to the common rule of this area.
Skin care item of the present invention, it is added with medicinal plant extract, and the effect of blood circulation promoting and blood stasis dispelling, QI invigorating spermatogenesis is arranged, and can improve the activity of antioxidase, stimulates the fibroblast vigor, strengthens collagen protein synthesis ability etc., the delaying decrepitude of skin process.Effectively suppress collagenase activity, give the cytoactive function; Can also improve superoxide dismutase (SOD) vigor, and bring into play its antioxidation and remove the free radical effect, recover cell normal physiological function, slow down aging; Can also effectively improve blood circulation, blood vessel dilating improves skin-nourishing, promotes skin metabolism, promotes the metabolism of cell, accelerates old and feeble Skin Cell nucleic acid and proteinic synthetic, increases skin smooth and elasticity, reduces skin hardness; Also inhibited to cutaneous pigmentation; The ability raise immunity has good antibacterial and anti-inflammation functions, effectively removes the skin surface noxious bacteria, prevents bacterial reproduction.
In addition, also be added with hydrolysis of keratin in the skin care item of the present invention, this keratin components can promote cell enlargement and collagen protein synthesis, reduces skin microgroove and wrinkle thereby improve skin texture; Can be through the improvement of collagen structure, and albumen and water molecules increase, and keeps skin moisturizing to promote skin consolidation and elasticity; Can also alleviate the skin rubescent or sensitive-skinned reaction relevant through the inflammatory reaction path that weakens PGE2 with inflammation; Can also increase the generation of superoxide dismutase (SOD) and glutathion, the protection not oxidated infringement that stress cause of skin and promote skin Lightening and beautiful improves the colour of skin.With respect to other keratin product, the special keratin components that the present invention uses has outstanding performance advantage.
To combine embodiment to introduce skin care item of the present invention in detail below.
Description of drawings
Fig. 1 is among the contrast experiment of experimental example, the block diagram of skin elasticity improvement value;
Fig. 2 is among the contrast experiment of experimental example, the block diagram of moisture content of skin change value;
Fig. 3 is among the contrast experiment of experimental example, the block diagram of skin glossiness change value;
Fig. 4 is among the contrast experiment of experimental example, the block diagram of SOD activity change value in the skin.
The specific embodiment
Embodiment one,
1, the preparation of medicinal plant extract:
With Radix Angelicae Sinensis 40%, Radix Ginseng 40% is put into Soxhlet extractor after Flos Lonicerae 20% is pulverized; The ethanol that adds 3 times of medicinal plants weight; Being heated to 50 ℃, is the extractant circulation extraction with ethanol under the normal pressure, and the extracting solution that is obtained adopts distilling under reduced pressure to concentrate; Distilling the spissated time volatilizees fully with ethanol and exceeds, and distills spissated product and is medicinal plant extract.
2, keratic preparation:
Keratin according to the invention is that animal hair is cleaned up, at organic base, in the TGA aqueous ammonium; At 60 ℃ of solubilizing reaction 2-8 hours, to filter, filtrating is with holding back quality 40-60kD dialysis bag; In mercaptoethanol 0.08% aqueous solution dialysis 30-50 hour, collect filtering residue; Filtrating is continued after the basic hydrolysis with holding back quality 3-4kD dialysis bag, and in mercaptoethanol 0.08% aqueous solution dialysis 40-60 hour, the collection filtering residue; Behind two kinds of filtering residue mix homogeneously, lyophilization obtains the white powder hydrolysis of keratin mixture that is mixed by molecular weight 40000-60000 and two kinds of keratin of molecular weight 3000-4000.
3, the preparation of skin care item
With cetearyl alcohol 2%, glyceryl stearate 0.5%, methyl glucose sesquistearate 0.8%, PEG-20 methyl glucose sesquistearate 1.2%; Caprylic/capric triglyceride 4%, isopropyl myristate 2%, pentaerythritol stearic acid ester 2 1%, tocopherol acetas 0.5%; C15-19 alkane 3%, Butyrospermum Parkii Oil 1%, polydimethylsiloxane 1.5% drops into the oil phase pot, is heated to 85 ℃; Be stirred to dissolving, temperature remains on about 85 ℃, obtains oil phase material, and is subsequent use.
In the water pot, add hot water, turn on agitator slowly adds carbomer 0.2%, to fully dissolving, is warming up to 85 ℃, obtains the water material, and is subsequent use.
The emulsifying pot is evacuated to-0.05MPa, and first suction 3/4 water material is then with in the oil phase raw material suction emulsifying pot; The remaining water material of suction again; Homogenizing 15 minutes is opened and is stirred, and adds triethanolamine 0.2%; Stir 5 minutes adding laureth-7/C13-14 alkane/polyacrylamides 0.5%, homogenizing is 2 minutes again.Open cooling water temperature, add medicinal plants when continuing stirring until 45 ℃ and extract 10%, keratin 1%, antiseptic (phenoxyethanol) 0.3% and essence 0.2% stir.Discharging to clean container fill when temperature is reduced to 38 ℃.
Embodiment two,
1, the preparation of medicinal plant extract
With medicinal plants: Semen Ginkgo 20%, Radix Codonopsis 20%, Radix Scutellariae 20%; Radix Ginseng 25% is put into Soxhlet extractor after Poria 15% is pulverized, and adds the water of 4 times of medicinal plants weight; Being heated to 80 ℃, is the extractant circulation extraction with water under the normal pressure, and the extracting solution that is obtained adopts distilling under reduced pressure to concentrate; Distilling the spissated time volatilizees fully with water and exceeds, and distills spissated product and is medicinal plant extract.
2, keratin preparation
Keratin according to the invention is that animal hair is cleaned up, at organic base, in the TGA aqueous ammonium; At 60 ℃ of solubilizing reaction 2-8 hours, to filter, filtrating is with holding back quality 40-60kD dialysis bag; In mercaptoethanol 0.08% aqueous solution dialysis 30-50 hour, collect filtering residue; Filtrating is continued after the basic hydrolysis with holding back quality 3-4kD dialysis bag, and in mercaptoethanol 0.08% aqueous solution dialysis 40-60 hour, the collection filtering residue; Behind two kinds of filtering residue mix homogeneously, lyophilization obtains the white powder hydrolysis of keratin mixture that is mixed by molecular weight 40000-60000 and two kinds of keratin of molecular weight 3000-4000.
3, the preparation of skin care item
With spermol 2%, stearyl alcohol 1%, glyceryl stearate 0.8%, methyl glucose sesquistearate 1.2%, PEG-20 methyl glucose sesquistearate 1.8%; Caprylic/capric triglyceride 6%, isopropyl myristate 3%, pentaerythritol stearic acid ester 2 1.5%, tocopherol acetas 0.8%; C15-19 alkane 4.5%, Butyrospermum Parkii Oil 1.5%, polydimethylsiloxane 2% drops into the oil phase pot, heats 85 ℃; Be stirred to dissolving, temperature remains on about 85 ℃, obtains oil phase material, and is subsequent use.
In the water pot, add hot water, turn on agitator slowly adds carbomer 0.2%, to fully dissolving, is warming up to 85 ℃, obtains the water material, and is subsequent use.
The emulsifying pot is evacuated to-0.05MPa, and first suction 3/4 water material is then with in the oil phase raw material suction emulsifying pot; The remaining water material of suction again; Homogenizing 15 minutes is opened and is stirred, and adds triethanolamine 0.2%; Stir 5 minutes adding laureth-7/C13-14 alkane/polyacrylamides 0.8%, homogenizing is 2 minutes again.Open cooling water temperature, add medicinal plant extract 15% when continuing stirring until 45 ℃, keratin 4%, antiseptic 0.3% and essence 0.3% stir.Discharging to clean container fill when temperature is reduced to 38 ℃.
Embodiment three,
1, the preparation of medicinal plant extract
With medicinal plants: Flos Lonicerae 15%, Semen Ginkgo 10%, Radix Angelicae Sinensis 15%, Radix Scutellariae 15%; Poria 15%, the Rhizoma Atractylodis Macrocephalae 10%, Rhizoma Chuanxiong 20% is put into after the pulverizing and alcoholic acid container is housed is added ethanol; Alcoholic acid amount is flooded medicinal plants and is got final product, and is heated to 50 ℃, and normal pressure soaks down, and soak time is 2 hours; Soak and finish to obtain extracting solution, carry out repeatedly 4 times, merge each time extracting solution through filtering; The extracting solution that obtained adopts distillation to concentrate, and distills the spissated time to volatilize fully with ethanol and exceed, and distills spissated product and is medicinal plant extract.
2, keratic preparation
Keratin according to the invention is that animal hair is cleaned up, at organic base, in the TGA aqueous ammonium; At 60 ℃ of solubilizing reaction 2-8 hours, to filter, filtrating is with holding back quality 40-60kD dialysis bag; In mercaptoethanol 0.08% aqueous solution dialysis 30-50 hour, collect filtering residue; Filtrating is continued after the basic hydrolysis with holding back quality 3-4kD dialysis bag, and in mercaptoethanol 0.08% aqueous solution dialysis 40-60 hour, the collection filtering residue; Behind two kinds of filtering residue mix homogeneously, lyophilization obtains the white powder hydrolysis of keratin mixture that is mixed by molecular weight 40000-60000 and two kinds of keratin of molecular weight 3000-4000.
3, the preparation of skin care item
With different hard ester alcohol 1%, behenyl alcohol 1%, glyceryl stearate 0.8%, methyl glucose sesquistearate 1.2%, PEG-20 methyl glucose sesquistearate 1.8%; Caprylic/capric triglyceride 6%, isopropyl myristate 3%, pentaerythritol stearic acid ester 2 1.5%, tocopherol acetas 0.8%; C15-19 alkane 4.5%, Butyrospermum Parkii Oil 1.5%, polydimethylsiloxane 2% drops into the oil phase pot, heats 85 ℃; Be stirred to dissolving, temperature remains on about 85 ℃, obtains oil phase material, and is subsequent use.
In the water pot, add hot water, turn on agitator slowly adds carbomer 0.2%, to fully dissolving, is warming up to 85 ℃, obtains the water material, and is subsequent use.
The emulsifying pot is evacuated to-0.05MPa, and first suction 3/4 water material is then with in the oil phase raw material suction emulsifying pot; The remaining water material of suction again; Homogenizing 15 minutes is opened and is stirred, and adds triethanolamine 0.2%; Stir 5 minutes adding laureth-7/C13-14 alkane/polyacrylamides 0.8%, homogenizing is 2 minutes again.Open cooling water temperature, add medicinal plant extract 15% when continuing stirring until 45 ℃, keratin 4%, antiseptic and essence are an amount of, stir.Discharging to clean container fill when temperature is reduced to 38 ℃.
Embodiment four,
1, the preparation of medicinal plant extract
With medicinal plants: Flos Lonicerae 5%, Semen Ginkgo 5%, Radix Codonopsis 5%, Radix Scutellariae 15%; Radix Angelicae Sinensis 10%, Radix Ginseng 15%, Poria 15%, the Rhizoma Atractylodis Macrocephalae 15%; Rhizoma Chuanxiong 15% is put into Soxhlet extractor after the pulverizing, add the ethanol of 3 times of medicinal plants weight, is heated to 50 ℃; Be the extractant circulation extraction with ethanol under the normal pressure, the extracting solution that is obtained adopts distilling under reduced pressure to concentrate, and distills the spissated time to volatilize fully with ethanol and exceed, and distills spissated product and is medicinal plant extract.
2, keratin preparation
Keratin according to the invention is that animal hair is cleaned up, at organic base, in the TGA aqueous ammonium; At 60 ℃ of solubilizing reaction 2-8 hours, to filter, filtrating is with holding back quality 40-60kD dialysis bag; In mercaptoethanol 0.08% aqueous solution dialysis 30-50 hour, collect filtering residue; Filtrating is continued after the basic hydrolysis with holding back quality 3-4kD dialysis bag, and in mercaptoethanol 0.08% aqueous solution dialysis 40-60 hour, the collection filtering residue; Behind two kinds of filtering residue mix homogeneously, lyophilization obtains the white powder hydrolysis of keratin mixture that is mixed by molecular weight 40000-60000 and two kinds of keratin of molecular weight 3000-4000.
3, the preparation of skin care item
With spermol 4%, glyceryl stearate 1%, methyl glucose sesquistearate 1.6%, PEG-20 methyl glucose sesquistearate 2.4%; Caprylic/capric triglyceride 8%, isopropyl myristate 4%, pentaerythritol stearic acid ester 2 2%, tocopherol acetas 1%; C15-19 alkane 6%, Butyrospermum Parkii Oil 2%, polydimethylsiloxane 3% drops into the oil phase pot, heats 85 ℃; Be stirred to dissolving, temperature remains on about 85 ℃, obtains oil phase material, and is subsequent use.
In the water pot, add hot water, turn on agitator slowly adds carbomer 0.2%, to fully dissolving, is warming up to 85 ℃, obtains the water material, and is subsequent use.
The emulsifying pot is evacuated to-0.05MPa, and first suction 3/4 water material is then with in the oil phase raw material suction emulsifying pot; The remaining water material of suction again; Homogenizing 15 minutes is opened and is stirred, and adds triethanolamine 0.2%; Stir 5 minutes adding laureth-7/C13-14 alkane/polyacrylamides 1%, homogenizing is 2 minutes again.Open cooling water temperature, add medicinal plant extract 20% when continuing stirring until 45 ℃, keratin 10%, antiseptic (phenoxyethanol) 0.3% and essence 0.2% stir.Discharging to clean container fill when temperature is reduced to 38 ℃.
Embodiment five,
1, keratin preparation
Keratin according to the invention is that animal hair is cleaned up, at organic base, in the TGA aqueous ammonium; At 60 ℃ of solubilizing reaction 2-8 hours, to filter, filtrating is with holding back quality 40-60kD dialysis bag; In mercaptoethanol 0.08% aqueous solution dialysis 30-50 hour, collect filtering residue; Filtrating is continued after the basic hydrolysis with holding back quality 3-4kD dialysis bag, and in mercaptoethanol 0.08% aqueous solution dialysis 40-60 hour, the collection filtering residue; Behind two kinds of filtering residue mix homogeneously, lyophilization obtains the white powder hydrolysis of keratin mixture that is mixed by molecular weight 40000-60000 and two kinds of keratin of molecular weight 3000-4000.
2, the preparation of medicinal plant extract
With medicinal plants: Flos Lonicerae 5%, Semen Ginkgo 10%, Radix Angelicae Sinensis 15%, Radix Scutellariae 15%; Radix Ginseng 15%, Poria 10%, the Rhizoma Atractylodis Macrocephalae 10%, Rhizoma Chuanxiong 10%; Radix Codonopsis 10% is put into after the pulverizing and alcoholic acid container is housed is added ethanol, and alcoholic acid amount is flooded medicinal plants and got final product, and is heated to 50 ℃; Normal pressure soaks down, and soak time is 2 hours, soaks and finishes to obtain extracting solution through filtering, and carries out repeatedly 4 times; Merge each time extracting solution, the extracting solution that is obtained adopts distillation to concentrate, and distills the spissated time to volatilize fully with ethanol and exceed, and distills spissated product and is medicinal plant extract.
3, the preparation of skin care item
With hard ester alcohol 3%, glyceryl stearate 1%, methyl glucose sesquistearate 1.6%, PEG-20 methyl glucose sesquistearate 2.4%; Caprylic/capric triglyceride 8%, isopropyl myristate 4%, pentaerythritol stearic acid ester 2 2%, tocopherol acetas 1%; C15-19 alkane 6%, Butyrospermum Parkii Oil 2%, polydimethylsiloxane 3% raw material such as item such as grade drops into the oil phase pot, heats 85 ℃; Be stirred to dissolving, temperature remains on about 85 ℃, obtains oil phase material, and is subsequent use.
In the water pot, add hot water, turn on agitator slowly adds carbomer 0.2%, to fully dissolving, is warming up to 85 ℃, obtains the water material, and is subsequent use.
The emulsifying pot is evacuated to-0.05MPa, and first suction 3/4 water material is then with in the oil phase raw material suction emulsifying pot; The remaining water material of suction again; Homogenizing 15 minutes is opened and is stirred, and adds triethanolamine 0.2%; Stir 5 minutes adding laureth-7/C13-14 alkane/polyacrylamides 1%, homogenizing is 2 minutes again.Open cooling water temperature, add medicinal plant extract 20% when continuing stirring until 45 ℃, keratin 10%, antiseptic (phenoxyethanol) 0.3% and essence 0.2% stir.Discharging to clean container fill when temperature is reduced to 38 ℃.
Embodiment six,
1, keratin preparation
Keratin according to the invention is that animal hair is cleaned up, at organic base, in the TGA aqueous ammonium; At 60 ℃ of solubilizing reaction 2-8 hours, to filter, filtrating is with holding back quality 40-60kD dialysis bag; In mercaptoethanol 0.08% aqueous solution dialysis 30-50 hour, collect filtering residue; Filtrating is continued after the basic hydrolysis with holding back quality 3-4kD dialysis bag, and in mercaptoethanol 0.08% aqueous solution dialysis 40-60 hour, the collection filtering residue; Behind two kinds of filtering residue mix homogeneously, lyophilization obtains the white powder hydrolysis of keratin mixture that is mixed by molecular weight 40000-60000 and two kinds of keratin of molecular weight 3000-4000.
2, the preparation of medicinal plant extract
With medicinal plants: Flos Lonicerae 5%, Semen Ginkgo 5%, Radix Codonopsis 10%, Radix Angelicae Sinensis 15%; Radix Scutellariae 10%, Radix Ginseng 10%, Poria 10%, the Rhizoma Atractylodis Macrocephalae 15%; Rhizoma Chuanxiong 20% is put into after the pulverizing and alcoholic acid container is housed is added ethanol, and alcoholic acid amount is flooded medicinal plants and got final product, and is heated to 50 ℃; Normal pressure soaks down, and soak time is 2 hours, soaks and finishes to obtain extracting solution through filtering, and carries out repeatedly 4 times; Merge each time extracting solution, the extracting solution that is obtained adopts distillation to concentrate, and distills the spissated time to volatilize fully with ethanol and exceed, and distills spissated product and is medicinal plant extract.
3, the preparation of skin care item
In the water pot, add hot water, turn on agitator slowly adds carbomer 0.2%, to fully dissolving, is warming up to 85 ℃, obtains the water material, and is subsequent use.
With cetearyl alcohol 4%, glyceryl stearate 1%, methyl glucose sesquistearate 1.6%, PEG-20 methyl glucose sesquistearate 2.4%; Caprylic/capric triglyceride 8%, isopropyl myristate 4%, pentaerythritol stearic acid ester 2 2%, tocopherol acetas 1%; C15-19 alkane 6%, Butyrospermum Parkii Oil 2%, polydimethylsiloxane 3% drops into the oil phase pot, heats 85 ℃; Be stirred to dissolving, temperature remains on about 85 ℃, obtains oil phase material, and is subsequent use.
The emulsifying pot is evacuated to-0.05MPa, and first suction 3/4 water material is then with in the oil phase raw material suction emulsifying pot; The remaining water material of suction again; Homogenizing 15 minutes is opened and is stirred, and adds triethanolamine 0.2%; Stir 5 minutes adding laureth-7/C13-14 alkane/polyacrylamides 1%, homogenizing is 2 minutes again.Open cooling water temperature, add medicinal plant extract 10% when continuing stirring until 45 ℃, keratin 5%, antiseptic and essence are an amount of, stir.Discharging to clean container fill when temperature is reduced to 38 ℃.
Experimental example:
One, skin care item of the present invention and basic skin care item compare experiment
Basic skin care item among this contrast experiment are meant and do not contain medicinal plant extract and keratic basic skin care item.
Choose 16 ages in the female volunteers of 25-50 between year, skin care item of the present invention are spread upon each volunteer's hand, smeared 1 time in per 24 hours; Continuous 12 days, and with do not contain medicinal plant extract and the contrast of keratic common skin care item, smear at every turn and measured the elasticity of smearing skin part in back 24 hours; Before each the mensuration, the experimenter is at constant temperature, (20 ℃ of constant humidity; 60%RH) laboratory stopped 15 minutes, measured skin elasticity (Cutometer SEM575) with the skin elasticity analyzer, and average measurement value and matched group are relatively; The 1st skin care item of the present invention are smeared parts of skin elasticity increases by 18%, and 2 skin elasticitys of the mat woven of fine bamboo strips increase by 6%, and 3 skin elasticitys of the mat woven of fine bamboo strips increase by 17%; 4 skin elasticitys of the mat woven of fine bamboo strips increase by 30%, and 5 skin elasticitys of the mat woven of fine bamboo strips increase by 10%, and 6 skin elasticitys of the mat woven of fine bamboo strips increase by 16%; 7 skin elasticitys of the mat woven of fine bamboo strips increase by 3%, and 8 skin elasticitys of the mat woven of fine bamboo strips increase by 12%, and 9 skin elasticitys of the mat woven of fine bamboo strips increase by 13%; 10 skin elasticitys of the mat woven of fine bamboo strips increase by 15%, and 11 skin elasticitys of the mat woven of fine bamboo strips increase by 15%, and 12 skin elasticitys of the mat woven of fine bamboo strips increase by 13%.
Can be found out by above-mentioned detection data: skin care item of the present invention are compared with common basic skin care item (not containing medicinal plant extract and keratin components), and skin care item of the present invention are to the skin elasticity effect of being significantly improved.
Two, skin care item of the present invention and only add medicinal plant extract or keratic basic skin care item compare experiment
Choose 16 ages in the female volunteers of 25-50 between year, skin care item of the present invention are spread upon each volunteer's hand, smeared 1 time in per 24 hours; Continuous 12 days, and with only add medicinal plant extract or the contrast of keratic basic skin care item, smear to measure after 12 days and smear skin part elasticity improvement value, glossiness change value, moisture content of skin change value; SOD activity change value in the skin; Get average value measured and compare, measure the block diagram shown in the numerical value drafting pattern 1-4
Among Fig. 1-Fig. 4, A is medicinal plant extract and the keratic skin care item experimental group of being added with of the present invention, and B is for only having added the medicinal plant extract experimental group, and C is for only having added keratic experimental group.Added medicinal plant extract and keratic embodiment synergistic function simultaneously by can obviously finding out among Fig. 1, Fig. 2, Fig. 3 and Fig. 4 to skin elasticity; Its skin elasticity improvement value, glossiness change value, moisture content of skin change value; SOD activity change value is obviously greater than only adding medicinal plant extract and only adding keratic skin care item to elasticity improvement value, glossiness change value, moisture content of skin change value, the data sum of SOD activity change value in the skin in the skin.
The above is merely preferred embodiment of the present invention, and is in order to restriction the present invention, not all within spirit of the present invention and principle, any modification of being done, is equal to replacement, improvement etc., all should be included within protection scope of the present invention.

Claims (5)

1. skin care item, the mass percent of its contained component and each component is following:
Medicinal plant extract 1%~20%,
Keratin 0.2%~10%,
Esters 5%~15%,
Oils 5%~11%,
High fatty alcohol class 1%-4%,
Emulsifying agent 2%~8%,
Carbomer 0.1%~0.4%,
Triethanolamine 0.1%~0.4%,
Antiseptic 0.1%~1.0%,
Essence 0.1%~1.0%,
Water surplus;
Said medicinal plants is selected from least three kinds in the following medicinal plants: Flos Lonicerae, Semen Ginkgo, Radix Codonopsis, Radix Angelicae Sinensis, Radix Scutellariae, Radix Ginseng, Poria, the Rhizoma Atractylodis Macrocephalae and Rhizoma Chuanxiong;
Said keratin is the hydrolysis of keratin mixture that quality 40000-60000D and two kinds of keratin of quality 3000-4000D mix.
2. skin care item as claimed in claim 1 is characterized in that, said esters is selected from one or more in the following material: caprylic/capric triglyceride, isopropyl myristate, pentaerythritol stearic acid ester 2 and tocopherol acetas.
3. skin care item as claimed in claim 1 is characterized in that, said oils is selected from one or more in the following material: C15-19 alkane, Butyrospermum Parkii Oil and polydimethylsiloxane.
4. skin care item as claimed in claim 1 is characterized in that, said high fatty alcohol class is selected from one or more in the following material: spermol, stearyl alcohol, cetearyl alcohol, isooctadecanol, behenyl alcohol.
5. skin care item as claimed in claim 1; It is characterized in that said emulsifying agent is selected from one or more in the following material: glyceryl stearate, methyl glucose sesquistearate, PEG-20 methyl glucose sesquistearate, laureth-7/C13-14 alkane/polyacrylamide.
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* Cited by examiner, † Cited by third party
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CN105520873A (en) * 2015-12-21 2016-04-27 太仓张根木生物科技有限公司 Traditional Chinese medicine anti-senescence skin cream

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CN102178617B (en) * 2011-05-09 2012-10-10 刘佩华 Protein skin care products having function of skin repair and care
CN103284909A (en) * 2013-05-29 2013-09-11 薛羽佳 Emulsifying agent-free protective cream
CN104055707A (en) * 2014-07-03 2014-09-24 广州丹奇日用化工厂有限公司 Skin nourishment cosmetic composite and preparation method thereof
CN105687000A (en) * 2014-11-25 2016-06-22 广西大学 Antioxidative wrinkle-removing skin-moistening kumquat peal cream
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CN105193651B (en) * 2015-08-24 2018-08-17 天津盛世永业科技发展有限公司 Have effects that whitening promotes the external skin-care composition of qi and blood, preparation and preparation method thereof
CN109415422B (en) * 2015-10-29 2022-08-16 庆北大学校产学协力团 Preparation method of ultralow molecular keratin peptide and application thereof
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CN106361664A (en) * 2016-11-27 2017-02-01 珍尔姿(广州)化妆品有限公司 Hydrating eye cream capable of improving eye skin
CN108451790B (en) * 2018-05-30 2023-06-06 海默斯(重庆)医学生物技术有限公司 Moisturizing essence containing hydrophilic keratin and preparation method thereof
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Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101199464A (en) * 2007-12-14 2008-06-18 天津天狮生物发展有限公司 Radix Arnebiae seu Lithospermi hand and fingernail cream and process for preparing same

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101199464A (en) * 2007-12-14 2008-06-18 天津天狮生物发展有限公司 Radix Arnebiae seu Lithospermi hand and fingernail cream and process for preparing same

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105520873A (en) * 2015-12-21 2016-04-27 太仓张根木生物科技有限公司 Traditional Chinese medicine anti-senescence skin cream

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