CN101406672B - Chinese medicinal liquor for treating hypertension - Google Patents
Chinese medicinal liquor for treating hypertension Download PDFInfo
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- CN101406672B CN101406672B CN2008101604766A CN200810160476A CN101406672B CN 101406672 B CN101406672 B CN 101406672B CN 2008101604766 A CN2008101604766 A CN 2008101604766A CN 200810160476 A CN200810160476 A CN 200810160476A CN 101406672 B CN101406672 B CN 101406672B
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Abstract
The invention discloses Chinese medicated liquor for treating hypertension and a preparation method thereof. The Chinese medicated liquor is prepared from sun-dried ginseng, Radix Astragali, bighead atractylodes rhizome, Tuckahoe, tuber fleeceflower root, dried rhizome of rehmannia, white paeony root, angelica, bupleurum, dried orange peel, sealwort, centipedes, pilose antler, stir-baked semen ziziphi spinosae, thinleaf milkwort root-bark, Indian bread with hostwood, licorice, walnut, raisins, white spirit and other raw materials. Combining the raw materials, the Chinese medicated liquor takes both qi and blood into consideration, coordinates defensive qi and nutritive qi, makes qi and blood circulating in the whole body, coordinates the relationship between yin and yan, combines deintoxication and nourishing, removing blood stasis without hurting human body, maintains normal upbearing and downbearing of qi and blood, thereby reducing blood pressure.
Description
Technical field
The present invention relates to oral medicinal herb medicated wine, especially treat hypertensive medicated wine and preparation method.
Background technology
Hypertension is one of common important cardiovascular and cerebrovascular disease that threatens at present human health, primary disease sickness rate height, the course of disease is long, be referred to as " lifelong sick " by people, it is dizzy, tired easily that clinical patient the lighter often feels headache, dizziness and tinnitus, insomnia cardiopalmus, agitation uncomfortable in chest, arteries and veins, angry, sometimes self is nervous, and is bored stiff.When serious the heart and brain renal dysfunction can take place, it is the main hazard factor of apoplexy and coronary heart disease.In early days and mid-term, symptom is often not obvious, and is ignored by people, in case cardiovascular and cerebrovascular complication occurs then become unmanageable health care problem.
Hypertensive pathogenic factor belongs to Liver and kidney more, imbalance of YIN and YANG, and as headache, dizziness, irritability, tinnitus, arteries and veins is dizzy etc., belongs to the pathological changes of liver.From traditional Chinese medical science angle, outer liver is not qi-blood disharmony, the lifting mistake department of spleen, the imbalance of YIN and YANG of kidney.With regard to ordinary circumstance, the hypertension initial stage starts from liver mostly, and then influences spleen, ascribes kidney at last to.Form deficiency of kidney yin, the hypertension of excessive rising of liver-YANG for seeing more.The case of a physically strong patient running a high fever of yang hyperactivity such as the headache of primary disease, dizzy, cardiopalmus, arteries and veins are dizzy resembles for mark, and deficiency of YIN-blood be an essence, and what consolidate disease we can say that it changes liver, and root is at kidney, and Liver and kidney influences other variations of generation each other.Kidney has negative and positive, according to the theory of interdependence between yin and yang, the deficiency of YIN can and the sun.The essence that blood pressure increases then is deficiency in both YIN and YANG, and the liver-fire rising is given birth in the wind syndrome caused by deficiency, apoplexy occurs and closes and take off disease.And then each organ blood supply insufficiency, each organ is kept the unevenness between supply and demand of normal blood, and especially the heart and brain kidney is the most important.The treatment primary disease at first will be supplied with the needed QI and blood of vitals, makes whole body QI and blood " rises the sixth of the twelve Earthly Branches and fall, fall the sixth of the twelve Earthly Branches and rise ", and operation is not put out regularly, reaches YIN and YANG in a relative equilibrium, and nutrient blood is full, freely suitable dynamic equilibrium of QI and blood, and blood pressure just can be stable at normal range.Execute according to differential diagnosis in tcm and to control, distinguish deficiency and excess, cold and heat adopt regulating YIN and YANG, correct visceral dysfunction so that the higher nervous center dysfunction, just can reach the purpose of blood pressure lowering.
Up to now, also do not find the report of any relevant Chinese medicine combination of the present invention.
Summary of the invention
The objective of the invention is to treat hypertensive oral medicinal herb medicated wine.
Another object of the present invention provides the preparation method of medicated wine of the present invention.
For achieving the above object, oral medicinal herb medicated wine of the present invention is to be come by the feedstock production of following weight parts: Radix Ginseng 15 grams, the Radix Astragali 30 grams, the Rhizoma Atractylodis Macrocephalae 12 grams, Poria 15 grams, Radix Polygoni Multiflori 20 grams, the Radix Rehmanniae 20 grams, the Radix Paeoniae Alba 15 grams, Radix Angelicae Sinensis 15 grams, Radix Bupleuri 10 grams, Pericarpium Citri Reticulatae 20 grams, Rhizoma Polygonati 18 grams, Cortex Phellodendri 9 grams, Cortex Eucommiae (parched) 25 grams, Radix Achyranthis Bidentatae 25 grams, Rhizoma Chuanxiong 10 grams, Ramulus Uncariae Cum Uncis 25 grams, Fructus Gardeniae 15 grams, Radix Salviae Miltiorrhizae 30 grams, Caulis Spatholobi 30 grams, Fructus Lycii 30 grams, Fructus Ligustri Lucidi 25 grams, Herba Ecliptae 30 grams, Radix Puerariae 30 grams, Cortex Lycii 30 grams, Herba Taxilli 30 grams, Fructus Corni 30 grams, Spica Prunellae 30 grams, Rhizoma Polygoni Cuspidati 18 grams, Herba Leonuri 30 grams, Herba Plantaginis 30 gram Herba Siegesbeckiaes 30 grams, Cortex Moutan 25 grams, Radix Rubiae 20 grams, Rhizoma Alismatis 20 grams, Flos Chrysanthemi Indici 25 grams, Semen Cassiae 30 grams, Rhizoma Curcumae Longae 20 grams, Herba Epimedii 25 grams, Herba Cistanches 20 grams, Semen Cuscutae 30 grams, Fructus Rubi 25 grams, Rhizoma Curculiginis 15 grams, Cortex Cinnamomi 12 grams, Radix Aconiti Lateralis Preparata 10 grams, Herba Cynomorii 25 grams, Radix Morindae Officinalis 20 grams, Semen Trigonellae 25 grams, Fructus Schisandrae Chinensis 15 grams, Concha Ostreae 18 grams, Fructus Rosae Laevigatae 18 grams, 4 of Scolopendras, Cornu Cervi Pantotrichum 20 grams, Semen Ziziphi Spinosae (parched) 20 grams, Radix Polygalae 16 grams, Poria cum Radix Pini's 20 grams, Radix Glycyrrhizae 15 grams, 2.5 kilograms of Semen Juglandis, 5 kilograms of dried Fructus Vitis viniferae, high quality liquor 45 degree-60 degree, 50 kilograms.
Scolopendra of the present invention is a Scolopendridae animal Scolopendpa Subspinipes Mutilans L. KOCH, the dry body of Scolopendrasubspinipesmutilans L.koch.Head two joint kermesinus, feeler and malicious hook are arranged, and each is a pair of, and back brown-green or blackish green is glossy, and two at vertical rib is arranged, the faint yellow or pale brown color of abdominal part, shrinkage, foot is held the better of black.
Radix Ginseng of the present invention is the dry root of Araliaceae Radix Ginseng Panaxginseng C.A.Mey.Conical or the capitate of walking back and forth of main root, long 3-15 centimetre, diameter 1-2 (or 3) centimetre.The upper end connects thin rhizome, the long 2-5.5 of rhizome centimetre.The bowl-shape stem trace of tool 4-6, the mutual arrangement, the other Chang Kejian winter tooth of top stem trace, 2-4 root and the thin lateral root of minority are told in the bottom, and long 8-12 centimetre, the supporting root bottom is given birth to how elongated fibrous root again, its surface has unconspicuous tiny verruca sometimes, and surperficial fallow is better.
Cornu Cervi Pantotrichum of the present invention is the young horn of the ossified close living fine hair in stag end of animal in deer family Cervus nippon Temminck Cervus nippontermminch or Cervus elaphus linnaeus Cerus elaphus linneus.Semen Juglandis of the present invention, dried Fructus Vitis viniferae are selected the full dry product of high-quality for use.
The present invention is with the above-mentioned raw materials compatibility: QI and blood is taken into account, soothing the liver circulation of qi promoting, cooling blood and removing stasis, strengthening spleen, tonifying kidney, clearing away heat-damp and promoting diuresis, yin nourishing is calmed the nerves, harmonizing yingfen and weifen makes QI and blood reach the whole body, negative and positive coordinated balance, benefit is arranged in attacking, and blood stasis dispelling and not being harmful to the health makes the QI and blood lifting that length be arranged, come in and go out in order, play nourishing the liver altogether, invigorate the spleen and warm the kidney, regulate the flow of vital energy, the merit of invigorating blood circulation, thus reach the purpose of blood pressure lowering.
The preparation method of medicated wine of the present invention is as follows:
The first step: adopt hot dipping to extract Scolopendra liquid
With the Scolopendra Scorpio of the fresh free from extraneous odour of complete drying, roguing, Ex-all, grind coarse powder, put into marmite or earthenware, add 500 milliliters of water proof heating of 65% ethanol simultaneously, treat to take out when water will boil, be embedded in the soil, stir once every day, 20 days winters, 10 days summers, take out and filter, clarification obtains Scolopendra liquid;
Second step: adopt hot dipping to extract Radix Aconiti Lateralis Preparata Rhizoma Curculiginis liquid
Fine Radix Aconiti Lateralis Preparata Rhizoma Curculiginis roguing Ex-all ground be coarse powder, put into earthenware, add 900 milliliters of 50% ethanol simultaneously, the water proof heating, water boils to take out in back 10 minutes and is embedded in the soil, and stirs once every day, and room temperature took out and filters in following 15 days, clarified, and obtained Radix Aconiti Lateralis Preparata Rhizoma Curculiginis liquid;
The 3rd step: adopt hot dipping to extract Radix Ginseng liquid
With Radix Ginseng, it is broken to pound flat rolling, puts into earthenware, adds 550 milliliters of 70% ethanol simultaneously, water proof heating, the water back of boiling is taken out to be placed on shady and cool place half an hour, and it is molten that the centre is stirred a rib every other day, under the room temperature 20-30 degree centigrade 15 days, filter, clarification, press residue squeezes clean the merging with liquid, makes Radix Ginseng liquid;
The 4th step: adopt hot dipping to extract antler liquid
The first planting two thick sticks saws Cornu Cervi Pantotrichum (band blood young pilose antler) is ground into coarser powder, puts into earthenware, add 680 milliliters of 75% ethanol simultaneously, the water proof heating treats that the water back 40min that boils takes out, and puts in the cool, and stir once every other day the centre, and 20d filters under the room temperature, and clarification obtains antler liquid;
The 5th step: adopt hot dipping to extract the sub-medicine feed liquid of tuber
With the Radix Astragali, the Rhizoma Atractylodis Macrocephalae, Radix Polygoni Multiflori, the Radix Rehmanniae, the Radix Paeoniae Alba, Radix Angelicae Sinensis, Pericarpium Citri Reticulatae, Rhizoma Polygonati, Cortex Phellodendri, Cortex Eucommiae (parched), Radix Achyranthis Bidentatae, Rhizoma Chuanxiong, Ramulus Uncariae Cum Uncis, Fructus Gardeniae, Radix Salviae Miltiorrhizae, Caulis Spatholobi, Fructus Lycii, Fructus Ligustri Lucidi, Radix Puerariae, Cortex Lycii, Herba Taxilli, Fructus Corni, Rhizoma Polygoni Cuspidati, Cortex Moutan, Rhizoma Alismatis, Semen Cassiae, Rhizoma Curcumae Longae, Herba Cistanches, Semen Cuscutae, Fructus Rubi, Cortex Cinnamomi, Herba Cynomorii, Radix Morindae Officinalis, Semen Trigonellae, Fructus Schisandrae Chinensis, Concha Ostreae, Fructus Rosae Laevigatae, Semen Ziziphi Spinosae (parched), Cortex et Radix Polygalae (processed), 38 flavor roguing Ex-alls are after the arrangement processing, the fritter that is ground into about 1cm mixes, and adds demineralized water in 1: 30 ratio, puts in the lixiviate filling, with 55-65 ℃ of insulation lixiviate 10-16h, the filtration filtering residue adds demineralized water in 1: 10 ratio, filters in 75-85 ℃ of insulation lixiviate 4-6h, merges secondary filtrate, gets the tuber herb liquid;
The 6th step: adopt hot dipping to extract leaf grass class medicine feed liquid
With Radix Bupleuri, Herba Ecliptae, Spica Prunellae, Herba Leonuri, Herba Plantaginis ， Herba Siegesbeckiae, Radix Rubiae, Flos Chrysanthemi Indici, Herba Epimedii, Radix Glycyrrhizae Preparata, Poria cum Radix Pini, Poria, after the 12 flavor roguing Ex-all arrangement processing, be ground into coarse powder and mix, add demineralized water in 1: 30 ratio, put in the lixiviate filling,, filter in 55-65 ℃ of insulation lixiviate 6-12h, filtering residue adds demineralized water in 1: 1 ratio, filters in 65-75 ℃ of insulation lixiviate 2-4h to merge twice filtrate, gets leaf grass herb liquid;
The 7th step: adopt three cold-macerations to extract walnut liquid
All get 75% deodorizing alcohol of 2 times of Semen Juglandis amounts when soaking with the second time for the first time and soaked Semen Juglandis 1 month; Soak for the third time and need use the soft water identical to soak 10 days with the Semen Juglandis amount.Take 3 days between soak period and stir once;
Above-mentioned three soaks are mixed the mixed Semen Juglandis extractive juice that gets;
Semen Juglandis marc after separating is distilled, and distillate is done allotment wine and is used;
The 8th step: the single entry fermentation method is produced the mediation wine
Dried Fructus Vitis viniferae is ground into graininess, puts into pot and add 2 times of water gagings and decoct, filter and remove residue when treating after boiling that bubble diminishes adds clarifiers such as pectase or sulfur dioxide then in filtrate, promptly gets Sucus Vitis viniferae after leaving standstill filtration;
The Sucus Vitis viniferae of producing is added wine unstrained spirits (Oryza glutinosa, distillers yeast) produce Fructus Vitis viniferae slurry wine according to a conventional method;
Fructus Vitis viniferae is starched wine be sent in the closed cell, add ethanol immediately and evenly stir to refine and produce wine, the addition of ethanol should guarantee that the alcohol content of Fructus Vitis viniferae slurry wine is greater than 16%-25%;
Wine after the alcoholization should be clarified in airtight special container 10-25 days, can add the secondary pectase in case of necessity, its clarification is accelerated, with the wine after the clarification, siphon moves in the hold-up vessel standby, makes the mediation wine;
The 9th step: the preparation of liquid glucose
High-quality crystal sugar, white sugar and water are added in the jacketed pan in 2: 3: 7 ratio, heat up and make its thawing, it is little faint yellow to treat that liquid glucose presents, limpid when transparent, and filtered while hot is cooled off standbyly, makes liquid glucose;
The tenth step: mix, blend
The lixiviating solution in the first step to the eight step is mixed, be blended into the high-quality pure grain Chinese liquor and the liquid glucose of 45-60 degree again, insert in the blending tank reuse demineralized water or distilled water together and quantitatively arrive 100L, fully mix stirring evenly, the wine base that add 50 degree then blend into 25 and spend;
Described wine base is treated edible ethanol, and processing procedure is: the edible ethanol with 95% (requirement reaches one-level ethanol) is diluted to the 50-65 degree, with potassium permanganate oxidation, activated carbon adsorption, lay equal stress on and steam deodorize, decaptitating truncates, and the section of heating up in a steamer wine is made wine base in getting, and adjusting the wine degree is 50 degree;
The 11 step: acid adjustment
In blending tank, add an amount of citric acid and make pH value reach 5-6, to proofread and correct local flavor according to basic wine sensory evaluation result;
The 12 step: aging
With the basic wine after the acid adjustment, be sealed in natural aging 2-4 week in the basin, with the assorted flavor that volatilizees, form some fragranced materials, make the mellow silk floss of wine body gentle, graceful fine and smooth, all flavors are coordinated, unique style, taste is soft;
The 13 step: filter, sterilize
Wine after the aging is further isolated fine solid shape float through diatomite filter (or flame filter press).In addition, for shelf-life and the storage period that prolongs wine, need take 85-90 ℃ sterilization in short-term (time is 25-30min).
The medicated wine quality standard of producing through said method of the present invention detects as follows:
Perfume and flavor: under the prerequisite of not losing the delicate fragrance type local flavor, have the delicate fragrance of graceful nature, harmonious spice fragrance.The wine degree is low and not light, and taste pure and sweet is agreeably sweet, and honey is and tasty and refreshing, and lingering fragrance is long.
Color and luster: wine liquid is orange, clear, no suspended substance, deposit-free.
The wine degree: (25 ℃, %) 25 ± 1 total acids are (with citric acid juice, g/100ml) 0.1-0.2.Pol (with Fructus Vitis viniferae syrup g/L)≤80.
Raw material of the present invention can also take the conventional method of Chinese medicine preparation to be prepared into any oral preparations.For example these crude drug (except that Semen Juglandis, dried Fructus Vitis viniferae) can being purified, it is for oral administration to incapsulate, and decoction can also be decocted in water for oral dose.But for each raw material that makes this medicine plays a role better, make introduction with wine, because wine can kill hundred evil poisones, promoting blood circulation, wet dissipation gas is supported temper, removes the wind therapeutic method to keep the adverse QI flowing downwards, and the advantage of utilizing wine and blood to promote blood circulation, and drug effect is played a role as early as possible.Therefore the psychological need that can also be fit to people specially is prepared into medicated wine.
Medicine of the present invention has the enhancing cell viability, human body immunity improving function, opposing body anoxia, slow down aging, allaying tiredness, yin nourishing is calmed the nerves, blood fat-reducing blood pressure-decreasing, kidney nourishing and blood enriching, beneficial bone replenishing essence, the strong body of strong waist, fill the Sheng QI and blood, soothing liver and strengthening spleen, clearing away heat-damp and promoting diuresis, multiple function such as cooling blood and removing stasis.
The present invention adapts to multiple crowd, is fit to modern's high standard urgent needs of quality of life, and collection health care is an one, with preparation method, and nutritional labeling and be worth result-medicated wine that curative effect is passed through concentrating on studies of more than ten years and clinical verification gained.
The present invention selects the Chinese crude drug in high-quality tunnel for use based on herbal raw material, and the part medical material is that occurring in nature is chosen, goods is true imitate strong.The selection of the wine base just fine grain wine of pure color of distinguishing the flavor of, fragrant and sweet, multiple collocation of each flavor design of acid has main body fragrant and auxiliary fragrant, and taste is suitable, and very lovers' likes and has a liking for.
Flavour of a drug of the present invention are heavy, and the strictness of calling in of fragrant material is accomplished with wine base harmoniously, accomplishes that Zhu Xiang does not appear, people drink medicated wine and do not produce the sensation of drinking Chinese medicine, but reach the effect that takes traditional Chinese medicine, and taking convenience, medicine-food two-purpose reaches the specially good effect of health care when having meal.
The property of the present invention is directed to is strong, is fit to various hypertension of each phase, takes for a long time to have no side effect, and can thoroughly cure hypertension, is one of human optimal Chinese medicine product.
The present invention also has other advantages, can strengthen resistance against diseases, anti-liver injury, and antioxidation promotes microcirculation, strengthens heat-resisting cold tolerance.Anticancer, antiviral, anti-flu.Can also improve life quality, to suffering from sexual dysfunction, sexual disorder, impotence and premature ejaculation is sombre to wait all that tool has a better role.
The present invention the most important thing is that medicine is worth, and is the medicated wine that has nourishing and treatment (blood pressure lowering) effect, and its use value is to drink not to be to take medicine, but can reach the effect of taking medicine.
The specific embodiment
Concrete enforcement of the present invention is not described in detail in this as described in the summary of the invention.
Need to prove, medicated wine of the present invention in take, whatever you like is taken or the whatever you like of going with rice or bread is drunk on an empty stomach, can not the alcohol user can water down with cold water and drink, or begin with low dose earlier, day clothes 3-4 time are limited in about 20-30ml at every turn.But the person of holding a lot of liquor every day 1-2 time, every day 50ml, or whatever you like drink-service, but can not be excessive.Eat fresh vegetables during taking, diet is fried more, and is pungent, and animal oil or rich oils are eaten or do not eaten to over-salty food less, the food of being a vegetarian more.And the pessimal stimulation of avoiding the central nervous system.
For verifying curative effect of the present invention, clinical out-patient's 381 examples of accepting for medical treatment, wherein model case as:
Wei Qinghai, the man, 43 years old, symptoms such as headache, dizzy, cardiopalmus, weak, insomnia, hypomnesis, anxiety, agitation, irritability, flushing, bitter taste, wiry forceful pulse appearred in lawyer sometimes.Under quiet condition, repeatedly measure blood pressure, blood pressure continues to increase the hypertension standard that reaches, diastolic pressure is greater than 130-140mlHg (17.3-18.6kpa), after clinical manifestation and getting rid of other secondary hypertensions, can be diagnosed as hypertension, and descend with serious life quality, through taking medicated wine 40d of the present invention, transference cure, blood pressure stabilization continues below 90 millimetress of mercury at diastolic pressure, and systolic pressure continues below 130 millimetress of mercury.
The deer book is bright, the man, 66 years old, the peasant, the tractor driver, before 5 years beginning ill, just disease is felt headache, dizziness, insomnia, cardiopalmus, uncomfortable in chest, irritated and tired easily often.Just used a little depressor earlier, Herba Apocyni veneti, Beijing blood pressure lowering " 0 " number class medicine, some alleviation of the state of an illness because my health care consciousness is relatively poor, is thought healthy enough to enjoy food and drinks and big problem can not occurred.Do not have when eating during medicine.In August, 05, PD serious insomnia occurs to certain phase, cardiopalmus asthma, and edema appears in dyspnea, and left ventricular hypertrophy and expansion cause heart failure on inspection, and systolic pressure is more than 200 millimetress of mercury, and diastolic pressure is about 150 millimetress of mercury.Life is near taking care of oneself.After taking Lu Zhenkang hundred million health promoting wine, adhered to drink-service in many days, at every turn about 80-120ml, 16d produce effects as a result, the 30d symptom is clearly better, and about blood pressure blood pressure lowering high pressure 140 millimetress of mercury, low pressure is about 90 millimetress of mercury.Take medicine wine 60 days, headache, dizziness, insomnia, all transference cures such as uncomfortable in chest.Blood pressure stabilization is between 85-135 now.Once take thing to visit, speaking an agitated tone: " your medicated wine of system really is goodies ".Now still adhere to taking.
Zhang Bingyou, the man, 55 years old, the teacher, ill before 6 years, 04 year seriously ill can't adhere to work, and the mastery of being in suffers from serious hypertension, and hyperlipidemia has been taken a large amount of hypertension and hyperlipemia medicines, and transfusion, some improvement of the state of an illness, but can not go to work.Progressively strong through taking medicated wine health of the present invention, blood pressure, blood fat are stabilized in normal person's scope, do not have trouble time flu in nearly 2 years, and now I am happy, and it is happy to work.
Zhou Guanghui, the man, 54 years old, the village secretary, ill before 4 years.Normal sense headache, dizziness and tinnitus, visual deterioration, insomnia cardiopalmus, agitation uncomfortable in chest, tired easily, stringy pulse.Took not Buddhist nun's Horizon, FUFANG LIXUEPING PIAN, Beijing blood pressure lowering " 0 " number class medicine, the state of an illness can be eased, owing to professional reason, irregularity in daily life, it is untimely to take medicine.When making arrangements of child's marriage, be in a bad way in May, 06, and the heart and brain renal dysfunction takes place, by taking medicated wine of the present invention 3 months, and rehabilitation now.
Below exemplify no longer one by one.
Above-mentioned 381 routine patients press above-mentioned dosage to the treatment hypertension, continuous use 90 days, and every 10d measures a blood pressure, and healing time specifies the treatment and the beneficial effect of medicated wine of the present invention through perusal by following table.
Subordinate list one: the observation of curative effect after treatment is statistical table as a result
Table two is sign improvement in January situation after treating
| Symptom | It is dizzy to have a headache | Insomnia cardiopalmus | Irritated irritability | Sexual dysfunction |
| Before the treatment (example) | 381? | 380? | 371? | 380? |
| Treatment back (example) | 380? | 378? | 371? | 380? |
| Total effective rate (%) | 99.74? | 99.47? | 100? | 100? |
In a word, treat 381 examples with medicated wine, as a result produce effects 190 examples, obvious effective rate 49.9% a middle of the month; 191 examples, improvement rate 50.1% take a turn for the better; Inefficiency 0%.Total effective rate 100%.
Claims (1)
1. the hypertensive Chinese medicine medicated wine of treatment is characterized in that, it is to be come by the feedstock production of following weight parts: Radix Ginseng 15 grams, the Radix Astragali 30 grams, the Rhizoma Atractylodis Macrocephalae 12 grams, Poria 15 grams, Radix Polygoni Multiflori 20 grams, the Radix Rehmanniae 20 grams, the Radix Paeoniae Alba 15 grams, Radix Angelicae Sinensis 15 grams, Radix Bupleuri 10 grams, Pericarpium Citri Reticulatae 20 grams, Rhizoma Polygonati 18 grams, Cortex Phellodendri 9 grams, Cortex Eucommiae (parched) 25 grams, Radix Achyranthis Bidentatae 25 grams, Rhizoma Chuanxiong 10 grams, Ramulus Uncariae Cum Uncis 25 grams, Fructus Gardeniae 15 grams, Radix Salviae Miltiorrhizae 30 grams, Caulis Spatholobi 30 grams, Fructus Lycii 30 grams, Fructus Ligustri Lucidi 25 grams, Herba Ecliptae 30 grams, Radix Puerariae 30 grams, Cortex Lycii 30 grams, Herba Taxilli 30 grams, Fructus Corni 30 grams, Spica Prunellae 30 grams, Rhizoma Polygoni Cuspidati 18 grams, Herba Leonuri 30 grams, Herba Plantaginis 30 Ke ， Herba Siegesbeckiaes 30 grams, Cortex Moutan 25 grams, Radix Rubiae 20 grams, Rhizoma Alismatis 20 grams, Flos Chrysanthemi Indici 25 grams, Semen Cassiae 30 grams, Rhizoma Curcumae Longae 20 grams, Herba Epimedii 25 grams, Herba Cistanches 20 grams, Semen Cuscutae 30 grams, Fructus Rubi 25 grams, Rhizoma Curculiginis 15 grams, Cortex Cinnamomi 12 grams, Radix Aconiti Lateralis Preparata 10 grams, Herba Cynomorii 25 grams, Radix Morindae Officinalis 20 grams, Semen Trigonellae 25 grams, Fructus Schisandrae Chinensis 15 grams, Concha Ostreae 18 grams, Fructus Rosae Laevigatae 18 grams, 4 of Scolopendras, Cornu Cervi Pantotrichum 20 grams, Semen Ziziphi Spinosae (parched) 20 grams, Cortex et Radix Polygalae (processed) 16 grams, Poria cum Radix Pini's 20 grams, Radix Glycyrrhizae Preparata 15 grams, 2.5 kilograms of Semen Juglandis, 5 kilograms of dried Fructus Vitis viniferae, 50 kilograms of high quality liquor 45 degree-60 degree;
Its making step is as follows:
The first step: adopt hot dipping to extract Scolopendra liquid
With the Scolopendra Scorpio of the fresh free from extraneous odour of complete drying, roguing, Ex-all, grind coarse powder, put into marmite or earthenware, add 500 milliliters of water proof heating of 65% ethanol simultaneously, treat to take out when water will boil, be embedded in the soil, stir once every day, 20 days winters, 10 days summers, take out and filter, clarification obtains Scolopendra liquid;
Second step: adopt hot dipping to extract Radix Aconiti Lateralis Preparata Rhizoma Curculiginis liquid
Fine Radix Aconiti Lateralis Preparata, Rhizoma Curculiginis roguing Ex-all are ground and be coarse powder, put into earthenware, add 900 milliliters of 50% ethanol simultaneously, water proof heating, water are boiled to take out in back 10 minutes and are embedded in the soil, and stir once every day, room temperature took out and filters in following 15 days, and clarification obtains Radix Aconiti Lateralis Preparata Rhizoma Curculiginis liquid;
The 3rd step: adopt hot dipping to extract Radix Ginseng liquid
With Radix Ginseng, it is broken to pound flat rolling, puts into earthenware, adds 550 milliliters of 70% ethanol simultaneously, water proof heating, the water back of boiling is taken out to be placed on shady and cool place half an hour, and it is molten that the centre is stirred a rib every other day, under the room temperature 20-30 degree centigrade 15 days, filter, clarification, press residue squeezes clean the merging with liquid, makes Radix Ginseng liquid;
The 4th step: adopt hot dipping to extract antler liquid
The first planting two thick sticks saws Cornu Cervi Pantotrichum is ground into coarser powder, puts into earthenware, add 680 milliliters of 75% ethanol simultaneously, the water proof heating treats that the water back 40min that boils takes out, and puts in the cool, and stir once every other day the centre, and 20d filters under the room temperature, and clarification obtains antler liquid;
The 5th step: adopt hot dipping to extract the sub-medicine feed liquid of tuber
With the Radix Astragali, the Rhizoma Atractylodis Macrocephalae, Radix Polygoni Multiflori, the Radix Rehmanniae, the Radix Paeoniae Alba, Radix Angelicae Sinensis, Pericarpium Citri Reticulatae, Rhizoma Polygonati, Cortex Phellodendri, Cortex Eucommiae (parched), Radix Achyranthis Bidentatae, Rhizoma Chuanxiong, Ramulus Uncariae Cum Uncis, Fructus Gardeniae, Radix Salviae Miltiorrhizae, Caulis Spatholobi, Fructus Lycii, Fructus Ligustri Lucidi, Radix Puerariae, Cortex Lycii, Herba Taxilli, Fructus Corni, Rhizoma Polygoni Cuspidati, Cortex Moutan, Rhizoma Alismatis, Semen Cassiae, Rhizoma Curcumae Longae, Herba Cistanches, Semen Cuscutae, Fructus Rubi, Cortex Cinnamomi, Herba Cynomorii, Radix Morindae Officinalis, Semen Trigonellae, Fructus Schisandrae Chinensis, Concha Ostreae, Fructus Rosae Laevigatae, Semen Ziziphi Spinosae (parched), Cortex et Radix Polygalae (processed), 38 flavor roguing Ex-alls are after the arrangement processing, the fritter that is ground into about 1cm mixes, and adds demineralized water in 1: 30 ratio, puts in the lixiviate filling, with 55-65 ℃ of insulation lixiviate 10-16h, the filtration filtering residue adds demineralized water in 1: 10 ratio, filters in 75-85 ℃ of insulation lixiviate 4-6h, merges secondary filtrate, gets the tuber herb liquid;
The 6th step: adopt hot dipping to extract leaf grass class medicine feed liquid
With Radix Bupleuri, Herba Ecliptae, Spica Prunellae, Herba Leonuri, Herba Plantaginis ， Herba Siegesbeckiae, Radix Rubiae, Flos Chrysanthemi Indici, Herba Epimedii, Radix Glycyrrhizae Preparata, Poria cum Radix Pini, Poria, after the 12 flavor roguing Ex-all arrangement processing, be ground into coarse powder and mix, add demineralized water in 1: 30 ratio, put in the lixiviate filling,, filter in 55-65 ℃ of insulation lixiviate 6-12h, filtering residue adds demineralized water in 1: 1 ratio, filters in 65-75 ℃ of insulation lixiviate 2-4h to merge twice filtrate, makes leaf grass herb liquid;
The 7th step: adopt three cold-macerations to extract walnut liquid
All get 75% deodorizing alcohol of 2 times of Semen Juglandis amounts when soaking with the second time for the first time and soaked Semen Juglandis 1 month; Soak for the third time and need use the soft water identical to soak 10 days, required between soak period stir once in 3 days with the Semen Juglandis amount;
Above-mentioned three soaks are mixed the mixed Semen Juglandis extractive juice that gets;
The 8th step: the single entry fermentation method is produced the mediation wine
Dried Fructus Vitis viniferae is ground into graininess, puts into pot and add 2 times of water gagings and decoct, filter and remove residue when treating after boiling that bubble diminishes adds pectase or sulfur dioxide clarifier then in filtrate, promptly gets Sucus Vitis viniferae after leaving standstill filtration;
The Sucus Vitis viniferae of producing is added the wine unstrained spirits produce Fructus Vitis viniferae slurry wine according to a conventional method;
Fructus Vitis viniferae is starched wine be sent in the closed cell, add ethanol immediately and evenly stir to refine and produce wine, the addition of ethanol should guarantee that the alcohol content of Fructus Vitis viniferae slurry wine is greater than 16%;
Wine after the alcoholization should be clarified in airtight special container 10-25 days, can add the secondary pectase in case of necessity, its clarification is accelerated, with the wine after the clarification, siphon moves in the hold-up vessel standby, makes the mediation wine;
The 9th step: the preparation of liquid glucose
High-quality crystal sugar, white sugar and water are added in the jacketed pan in 2: 3: 7 ratio, heat up and make its thawing, it is little faint yellow to treat that liquid glucose presents, limpid when transparent, and filtered while hot is cooled off standbyly, makes liquid glucose;
The tenth step: mix, blend
The lixiviating solution in the first step to the eight step is mixed, be blended into the high-quality pure grain Chinese liquor and the liquid glucose of 45-60 degree again, insert in the blending tank reuse demineralized water or distilled water together and quantitatively arrive 100L, fully mix stirring evenly, the wine base that add 50 degree then blend into 25 and spend;
Described wine base is treated edible ethanol, and processing procedure is: the edible ethanol with 95% is diluted to the 50-65 degree, and with potassium permanganate oxidation, activated carbon adsorption, laying equal stress on steams deodorize, and decaptitating truncates, and the section of heating up in a steamer wine is made wine base in getting, and adjusting the wine degree is 50 degree;
The 11 step: acid adjustment
Adding an amount of citric acid in blending tank makes pH value reach 5-6;
The 12 step: aging
With the basic wine after the acid adjustment, be sealed in natural aging 2-4 week in the basin, with the assorted flavor that volatilizees;
The 13 step: filter, sterilize
Wine after the aging is further isolated fine solid shape float through diatomite filter or flame filter press, and take the sterilization in short-term of 85-90 ℃ 25-30min.
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| CN101559176B (en) * | 2009-05-19 | 2011-09-07 | 曹桂景 | Chinese materia medica preparation for lowering blood pressure |
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| CN101559176B (en) * | 2009-05-19 | 2011-09-07 | 曹桂景 | Chinese materia medica preparation for lowering blood pressure |
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