CN101385803B - Compound Chinese herbal medicine extract liquid for preventing and treating livestock and birds diarrhea and preparation thereof - Google Patents
Compound Chinese herbal medicine extract liquid for preventing and treating livestock and birds diarrhea and preparation thereof Download PDFInfo
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Abstract
The invention provides a compound Chinese medicinal herb extract for preventing and treating livestock and poultry diarrhea and a preparation method thereof. The extract is made from paulownia flower, purslane, ciderage, geranium, garden burnet root, copperleaf and cactus, the raw medicinal materials comprise parts as follows by weight: 29-35 parts of the paulownia flower, 22-28 parts of the purslane, 20-26 parts of the ciderage, 17-23 parts of the geranium, 17-23 parts of the garden burnet, 13-17 parts of the copperleaf and 8-12 parts of the cactus. The preparation process of the compound Chinese medicinal herb extract comprises the following steps: selection of the raw medicinal materials, washing, herb cutting, primary aqueous extraction, secondary aqueous extraction, decoction combination, condensing, filling and packaging. The compound Chinese medicinal herb extract preparation for preventing and treating the livestock and poultry diarrhea has the efficacies on eliminating dampness and stopping diarrhea, and mainly treating diarrhea and enteritis, and has the advantages of naturalness, no residue, no drug tolerance and the like.
Description
Technical field
The present invention relates to prevent and treat the medicine of digestive tract or digestive system disease, be meant a kind of compound Chinese medicinal herb extract of preventing and treating livestock and poultry diarrhea and preparation method thereof especially.
Background technology
Livestock and poultry diarrhea is one of digestive tract disease comparatively common in the livestock breeding industry, and the generation of livestock and poultry diarrhea disease often brings very big economic loss to the raiser.On the current market; Mostly the medicine that is used to prevent and treat diarrhea of livestock and birds is antibiotic, chemical synthetic drug etc.; Though can bringing into play certain curative effect, these medicines reach certain prevention effect; But also brought a series of insoluble problems such as Resistant strain increase and drug residue simultaneously, seriously restricted the sound development of livestock breeding industry.Although present domestic market begins to occur the Chinese medicine preparation that some are used to prevent and treat livestock and poultry diarrhea, wherein great majority are merely the ground product of crude drug, exist the defective that active constituent content is low, the control uncertain therapeutic efficacy is cut.
Summary of the invention
Technical problem to be solved by this invention just is to prevent and treat the defective that the livestock and poultry diarrhea medicine exists to being used at present, provides that a kind of curative effect of medication is definite, the treatment effective percentage is high, the compound Chinese medicinal herb extract of the control livestock and poultry diarrhea of safe drug residue free and preparation method thereof.The compound Chinese medicinal herb extract of control livestock and poultry diarrhea of the present invention is prepared from Flos Paulowniae, Herba Portulacae, Herba polygoni hydropiperis, Herba Erodii, Radix Sanguisorbae, Herba Acalyphae and Radix et Caulis Opuntiae Dillenii, and the weight proportion scope of crude drug is: Flos Paulowniae 29-35 part, Herba Portulacae 22-28 part, Herba polygoni hydropiperis 20-26 part, Herba Erodii 17-23 part, Radix Sanguisorbae 17-23 part, Herba Acalyphae 13-17 part and Radix et Caulis Opuntiae Dillenii 8-12 part.Said herbal medicine through pick, clean, cut medicine, water is carried first, secondary water is carried, collecting decoction, concentrate the compound Chinese medicinal herb extract make the control livestock and poultry diarrhea.The weight proportion commonly used of crude drug is: 10 parts of 32 parts of Flos Paulowniaes, 25 parts of Herba Portulacaes, 23 parts of Herba polygoni hydropiperis, 20 parts of Herba Erodiis, 20 parts of Radix Sanguisorbaes, 15 parts of Herba Acalyphaes and Radix et Caulis Opuntiae Dilleniis.
The compound Chinese medicinal herb extract that the present invention is used to prevent and treat livestock and poultry diarrhea is the basis in a large amount of investigation and practice; Design function according to product requires more than 200 kinds of Chinese herbal medicine are screened; Monarch, seven emotions compatibility, eighteen incompatible medicaments nineteen medicaments of mutual restraint scheduling theory according to Chinese medicine; Screening and the Chinese herbal medicine effective ingredients, the bacteriostasis that filter out extracted, verify is one by one finally confirmed prescription.The pharmacology situation of each component is in the prescription: (1) Flos Paulowniae: cold in nature for the flower of goatweed Paulownia, and mildly bitter flavor.Heat-clearing and toxic substances removing.Be used for bronchitis, acute tonsillitis, bacillary dysentery, acute enteritis, acute conjunctivitis, parotitis, furuncle and phyma.(2) Herba Portulacae: be the annual meat herbaceous plant of Portulacaceae, heat-clearing and toxic substances removing, cooling blood for hemostasis.Be used for toxic-heat and blood stasis, carbuncle is treated skin ulcer, eczema, and erysipelas, snake bite and insect sting is had blood in stool, dysentery.Research shows; Herba Portulacae contains multiple chemical constituents with medical value such as abundant fatty acid, volatile oil, polysaccharide, aminoacid, vitamin and mineral, has the pharmacological action of waiting for a long time of enhance immunity, blood fat reducing, blood sugar lowering, antibiotic, antitumor, antioxidation and health care.The Herba Portulacae ethanol extraction has significant inhibitory effect to dysentery bacterium and bloody dysentery bacillus; And various common food pollution bacterium such as escherichia coli, Salmonella, shigella, staphylococcus aureus, Bacillus proteus, bacillus subtilis etc. had stronger inhibitory action; Even be diluted at 12.5% o'clock, still have certain bacteriostasis.In addition, to the lymphopoietic influence of rabbit, the result shows that Herba Portulacae can significantly improve the lymphocytic multiplication capacity of rabbit to He Shengwen etc. through the research Herba Portulacae.(3) Herba polygoni hydropiperis: acrid in the mouth, warm in nature, main component are polygodial, confertifolin, polygonone, persicarin etc.Has expelling wind and removing dampness, eliminating stasis to stop pain, removing toxic substances and promoting subsidence of swelling, killing parasites for relieving itching effect.Be usually used in dysentery, gastroenteritis, diarrhoea clinically, rheumatic arthritis, treating swelling and pain by traumatic injury, dysfunctional uterine hemorrhage; Venom is controlled in external, skin eczema.(4) Herba Erodii: hot, bitter, flat, return the liver,kidney,spleen warp, contain compositions such as volatile oil, Quercetin, tannin, gallic acid, succinic acid, Quercetin and glycoside thereof, have wind-damp dispelling, the meridian dredging, antidiarrheal dysentery effect.Its herb decoct has than the obvious suppression effect micrococcus catarrhalis, staphylococcus aureus, bacterium flexneri, beta chain coccus, streptococcus pneumoniae etc.; The 68-1 of section strain of influenza A virus capital, Asia and the strain of parainfluenza virus I type celestial platform are also had than the obvious suppression effect.Be used for rheumatic arthralgia clinically, numbness contracture, muscle creatine pain, dysentery more.(5) Radix Sanguisorbae: another name Matteuccia struthiopteri, spouting bleeding from anus grass etc., bitter in the mouth, acid, puckery, cold nature.Contain zigu-glucoside, sangushsorbin A, B, E and gallic acid, tannin etc., have cooling blood for hemostasis, the skin ulcer effect is held back in detoxifcation, clinically be used to have blood in stool, hemorrhoidal bleeding, dysentery, metrorrhagia, burn due to hot liquid or fire, carbuncle sore tumefacting virus.(6) Herba Acalyphae: bitter in the mouth, puckery, cool in nature, GUIXIN, lung meridian.Be rich in alkaloid, flavonoid glycoside, phenols.Have heat-clearing and toxic substances removing, dampness removing, astringing to arrest bleeding effect.Clinically be mainly used to enteritis, dysentery, haematemesis, epistaxis, have blood in stool, hematuria, metrorrhagia, carbuncle furuncle infections, skin eczema.(7) Radix et Caulis Opuntiae Dillenii: bitter in the mouth, cool in nature.Be rich in compositions such as alkaloid, flavonoid such as flavonol, sterols such as sitosterol and oils and fats, protein, polysaccharide, trace element.Have heat-clearing and toxic substances removing, dissipating blood stasis for subsidence of swelling, benefiting stomach and stopping pain, antitussive effect, be used for stomach, duodenal ulcer, acute dysentery, cough, mastitis, carbuncle furuncle and phyma poison, venom, burn and scald etc.
The preparation flow that the present invention is used to prevent and treat the compound Chinese medicinal herb extract of livestock and poultry diarrhea is: and the water of the picking → clean of crude drug → cut medicine → first carries → and secondary water carries → collecting decoction → concentrate → fill → packing.
The major control condition:
Operating ambient temperature: 18-30 ℃, relative humidity 30-70%, the clean rank of production area is general production area;
Water is proposed control: water drawings water quality standard is a drinking water, and water is carried 10 times (W/W) that amount of water is an inventory first, and material adds the back and soaked 2 hours, and extraction time is 2 hours, and extracting the control temperature is 100 ℃, and mixing speed is 24 rev/mins; The amount of water that secondary water is carried is 5 times (W/W) of inventory, and extraction time is 1 hour, and extracting the control temperature is 100 ℃, and mixing speed is 24 rev/mins;
Concentrate control: under stirring, adopt the Steam Heating mode to concentrate; 40 rev/mins of speeds of agitator; Mixing time 15 minutes; The heating-up temperature that is heated medicinal liquid in the control concentration heater is 80～100 ℃, and vacuum is-0.4～0.6 MPa, and medicinal liquid is concentrated into and the crude drug identical weight.
The compound Chinese medicinal herb extract that is used to prevent and treat livestock and poultry diarrhea prepares the concrete steps of process:
1, picking the crude drug lay in picking on the platform of crude drug sorted out the impurity in the crude drug one by one.
2, clean and will put in the service sink through the crude drug of picking, with the drinking water washing, and the medical material after will washing puts into second service sink and embathes, and cleans in the rearmounted container to drain away the water.
3, cut medicine and according to routine the tubers crude drug is put and be cut into lamellar in the medicine cutter, and will need the crude drug of coarse crushing to put coarse crushing in the boulder crusher, put into container, it is for use to send into next procedure.
4, water is carried
4.1, prepare burden operating ambient temperature: 18-30 ℃ relative humidity 30-70% according to each component of weight proportion weighing of crude drug;
4.2 water is carried the drinking water that in extraction pot, is incorporated as inventory 10 times (W/W) first, starts stirring motor, mixing speed is 24 rev/mins;
Carry in the jar 4.3 required various Chinese herbal medicine are joined water, material soaked 2 hours;
4.4 adopt extractions that heat up of Steam Heating mode, to open steam valve and heat up, control extraction temperature is 100 ℃, keeps after 2 hours first water to propose end, and the medicinal liquid that has extracted is delivered to storage tank after filtering;
4.5 in extraction pot, add the drinking water of inventory 5 times (W/W) when secondary water is carried; Repeat 4.3,4.4 steps; Mixing speed is 24 rev/mins; Wait to be warming up to 100 ℃ of materials and boil extraction time when reaching 1 hour, the steam off inlet valve extracts good medicinal liquid with secondary water and is transported to storage tank after filtering;
Carry the extracted twice liquid of carrying with secondary water 4.6 merge first water.
5, the merging medicinal liquid that concentrates after water carried is transported to concentration heater through head tank; Under stirring, adopt the Steam Heating mode to concentrate 40 rev/mins of speeds of agitator, mixing time 15 minutes; Opening steam valve heats up concentrated; The heating-up temperature that is heated medicinal liquid in the control concentration heater is 80～100 ℃, and vacuum is-0.4～0.6 MPa, until being concentrated into and the crude drug identical weight.
6, fill places Packaging Bottle on the feed hopper of confession bottle machine of fill train line, and loading amount is according to the rules carried out the fill of product.And open automatic labeling machine Packaging Bottle is carried out decals.
7, packaging product is packed in the packing crates, and on packing crates the Paste Product label.
8, warehouse-in deposits packaged product in warehouse for finished product.
The technical specification of compound Chinese medicinal herb extract finished product of preventing and treating livestock and poultry diarrhea through above method being used to of making is following:
| Sequence number | Project | Index |
| 1 | Character | Rufous is to brown liquid |
| 2 | PH value | 4.0～5.0 |
| 3 | Relative density | 1.02～1.08 |
| 4 | Effective ingredient (total flavones) content | ≥6.6mg/ml |
Advantage of the present invention has the removing dampness dysentery relieving with regard to being the compound Chinese medicinal herb extract preparation of preventing and treating livestock and poultry diarrhea; Cure mainly dysentery, enteritis effect; Because product of the present invention is through crude drug extraction, concentrated making; Thereby this extracting solution preparation possesses the active constituent content height, and using dosage is little, be easy to administration and have natural sex, noresidue, advantage such as have no drug resistance.The compound Chinese medicinal herb extract preparation of control livestock and poultry diarrhea of the present invention all has good restraining and killing action to encountered pathogenic such as escherichia coli, Salmonella, rotavirus, epidemic diarrhea virus and the TGE etc. that cause livestock and poultry diarrhea, through repairing intestinal mucosa, helping the intestinal microecology flora to rebuild.And the compound Chinese medicinal herb extract preparation of control livestock and poultry diarrhea of the present invention is remarkable to the trophism diarrhea effect that causes owing to protein content in the feedstuff is too high.The compound Chinese medicinal herb extract preparation of control livestock and poultry diarrhea of the present invention over 2 years through in Shandong, the 120 tame pig farms in a plurality of provinces such as Henan, Hebei, Jiangsu and 85 tame broiler plants on probation; Through irritating clothes or spice administration, according to every 1kg body weight 0.1-0.2m1, every day 2 times; Logotype 3 days; The result shows that the cure rate to bacillary, viral and trophism diarrhea reaches more than 95%, simultaneously the filling regularly of these article is obeyed or is made an addition in the feedstuff, and pig, chicken diarrhea are had the excellent prevention effect.Therefore the compound Chinese medicinal herb extract of control livestock and poultry diarrhea of the present invention has the vast market promotion prospect.
The specific embodiment
Below be embodiments of the invention, the actual use of the present invention is not limited to embodiment.
Embodiment 1, compound Chinese medicinal herb extract of control livestock and poultry diarrhea and preparation method thereof
The compound Chinese medicinal herb extract method for preparing that adopts the present invention to prevent and treat livestock and poultry diarrhea prepares extracts of Chinese herbal medicine; Crude drug is made up of Flos Paulowniae, Herba Portulacae, Herba polygoni hydropiperis, Herba Erodii, Radix Sanguisorbae, Herba Acalyphae and Radix et Caulis Opuntiae Dillenii, and the weight proportion of crude drug is Flos Paulowniae 32kg, Herba Portulacae 25kg, Herba polygoni hydropiperis 23kg, Herba Erodii 20kg, Radix Sanguisorbae 20kg, Herba Acalyphae 15kg and Radix et Caulis Opuntiae Dillenii 10kg.
Main production equipments
| Sequence number | Device name | Type and spec | Quantity |
| 1 | Reciprocating type medicine cutter | WQY240 | 1 |
| 2 | Boulder crusher | MZ200 | 1 |
| 3 | Dynamic extraction pot | 3m 3 | 1 |
| 4 | Basin | 3m 3 | 1 |
| 5 | The magnetically-actuated reflux pump | 40CQ-2 | 1 |
| 6 | The scraper-type vacuum concentrator | 1m 3 | 1 |
| 7 | Head tank | 1m 3 | 1 |
| 8 | Tube still heater | 200m 2 | 1 cover |
| 9 | Preparing tank | 1000L | 1 |
| 10 | Supply the bottle machine | 4P | 1 |
| 11 | Cover whirling Machine | Y4 | 1 |
| 12 | Electronic balance | JJ2000 | 1 |
| 13 | Labelling machine | LT | 1 |
| 14 | The filling liquid unit | YG | 1 cover |
| 15 | Electronic platform scale | TCS-30 | 1 |
The major control condition:
Operating ambient temperature: 18-30 ℃, relative humidity 30-70%, the clean rank of production area is general production area;
Water is proposed control: water drawings water quality standard is a drinking water, and water is carried 10 times (W/W) that amount of water is an inventory first, and material adds the back and soaked 2 hours, and extraction time is 2 hours, and extracting the control temperature is 100 ℃, and mixing speed is 24 rev/mins; The amount of water that secondary water is carried is 5 times (W/W) of inventory, and extraction time is 1 hour, and extracting the control temperature is 100 ℃, and mixing speed is 24 rev/mins;
Concentrate control: under stirring, adopt the Steam Heating mode to concentrate; 40 rev/mins of speeds of agitator; Mixing time 15 minutes; The heating-up temperature that is heated medicinal liquid in the control concentration heater is 80～100 ℃, and vacuum is-0.4～0.6 MPa, and medicinal liquid is concentrated into and the crude drug identical weight.
To operate according to following operation by the crude drug of proportioning preparation:
1, picking the crude drug lay in picking on the platform of crude drug sorted out the impurity in the crude drug one by one.
2, clean and will put in the service sink through the crude drug of picking, with the drinking water washing, and the medical material after will washing puts into second service sink and embathes, and cleans in the rearmounted container to drain away the water.
3, cut medicine and according to routine the tubers crude drug is put in the reciprocating type medicine cutter and be cut into lamellar, and will need the crude drug of coarse crushing to put coarse crushing in the boulder crusher, put into container, it is for use to send into next procedure.
4, water is carried
4.1, prepare burden operating ambient temperature: 18-30 ℃ relative humidity 30-70% according to each component of weight proportion weighing of crude drug;
4.2 the drinking water that is 1450kg is carried and in dynamic extraction pot, be incorporated as inventory 10 times (W/W) to water first, starts stirring motor, mixing speed is 24 rev/mins;
4.3 required various Chinese herbal medicine are joined in the dynamic extraction pot, and material soaked 2 hours;
4.4 adopt extractions that heat up of Steam Heating mode, to open steam valve and heat up, control extraction temperature is 100 ℃, keeps after 2 hours first water to propose end, and the medicinal liquid that has extracted is delivered to basin after filtering;
4.5 in dynamic extraction pot, add the drinking water of 5 times of (W/W) 725kg of inventory when secondary water is carried; Repeat 4.3,4.4 steps; Mixing speed is 24 rev/mins; Wait to be warming up to 100 ℃ of materials and boil extraction time when reaching 1 hour, the steam off inlet valve extracts good medicinal liquid with secondary water and is transported to storage tank after filtering;
Carry the extracted twice liquid of carrying with secondary water 4.6 merge first water.
5, the merging medicinal liquid that concentrates after water carried is transported to the scraper-type vacuum concentrator through head tank; Under stirring, adopt the Steam Heating mode to concentrate 40 rev/mins of speeds of agitator, mixing time 15 minutes; Opening steam valve heats up concentrated; The heating-up temperature that is heated medicinal liquid in the control scraper-type vacuum concentrator is 80～100 ℃, and vacuum is-0.4～0.6 MPa, be concentrated into the crude drug identical weight be 145kg.
6, fill places Packaging Bottle on the feed hopper of confession bottle machine of fill train line, and loading amount is according to the rules carried out the fill of product.
7, packing is opened automatic labeling machine Packaging Bottle is carried out decals, and by the regulation loading amount product is packed in the packing crates, and on packing crates the Paste Product label.
8, warehouse-in deposits packaged product in warehouse for finished product.
The compound Chinese medicinal herb extract finished product of the control livestock and poultry diarrhea that makes according to above method reaches following technical specification:
The compound Chinese medicinal herb extract finished product technical specification of control livestock and poultry diarrhea
| Sequence number | Project | Index |
| 1 | Character | Rufous is to brown liquid |
| 2 | PH value | 4.7 |
| 3 | Relative density | 1.03 |
| 4 | Effective ingredient (total flavones) content | 6.8mg/ml |
Through 15 families, amount to 176 piglets that suffer from Hakuri and use this finished product, according to the consumption use of 0.2ml/kg body weight; Every day 2 times, logotype 3 days, result: cure 162; 11 of being clearly better of symptom, show that this invention is used to treat the diarrheal total effective rate and reaches 98.3% by dead 3.Use the finished product that this method makes simultaneously and make an addition in the chickling daily ration of suffering from Hakuri, use according to the addition of 5ml/kg feedstuff, logotype 3 days, the result shows that the cure rate of the test chicken of this finished product set of applications reaches 93.65%.The pig that the finished product that this method is made is used for having loose bowels because of the too high trophism that causes of daily ration protein content only, method for using is with the Therapeutic Method of piglet pujos blancos, logotype is after 3 days, as a result in 63 sick pigs 61 return to one's perfect health, other 2 symptoms are clearly better.
Embodiment 2, compound Chinese medicinal herb extract of control livestock and poultry diarrhea and preparation method thereof
The compound Chinese medicinal herb extract method for preparing that adopts the present invention to prevent and treat livestock and poultry diarrhea prepares extracts of Chinese herbal medicine; Crude drug is made up of Flos Paulowniae, Herba Portulacae, Herba polygoni hydropiperis, Herba Erodii, Radix Sanguisorbae, Herba Acalyphae and Radix et Caulis Opuntiae Dillenii, and the weight proportion of crude drug is Flos Paulowniae 29kg, Herba Portulacae 22kg, Herba polygoni hydropiperis 20kg, Herba Erodii 17kg part, Radix Sanguisorbae 17kg, Herba Acalyphae 13kg part and Radix et Caulis Opuntiae Dillenii 8kg.
Main production equipments, major control condition and production process are with embodiment 1.
The compound Chinese medicinal herb extract finished product of the control livestock and poultry diarrhea that makes reaches following technical specification:
| Sequence number | Project | Index |
| 1 | Character | Rufous is to brown liquid |
| 2 | PH value | 4.8 |
| 3 | Relative density | 1.05 |
| 4 | Effective ingredient (total flavones) content | 7.1mg/ml |
The consumption of the extracts of Chinese herbal medicine that adopts said method to make according to 5 milliliters in per kilogram feedstuff made an addition in chickling (1-7 age in days) feedstuff; Compare with matched group; The incidence rate of matched group Pullorum Disease is 15%, and the incidence rate of the test group Pullorum Disease of this Chinese herbal and crude drugs preparations of interpolation application said method production is 0.35%.
Embodiment 3, compound Chinese medicinal herb extract of control livestock and poultry diarrhea and preparation method thereof
The compound Chinese medicinal herb extract method for preparing that adopts the present invention to prevent and treat livestock and poultry diarrhea prepares extracts of Chinese herbal medicine; Crude drug is made up of Flos Paulowniae, Herba Portulacae, Herba polygoni hydropiperis, Herba Erodii, Radix Sanguisorbae, Herba Acalyphae and Radix et Caulis Opuntiae Dillenii, and the weight proportion of crude drug is Flos Paulowniae 35kg, Herba Portulacae 28kg, Herba polygoni hydropiperis 26kg, Herba Erodii 23kg, Radix Sanguisorbae 23kg, Herba Acalyphae 17kg and Radix et Caulis Opuntiae Dillenii 12kg.
Main production equipments, major control condition and production process are with embodiment 1.
The compound Chinese medicinal herb extract finished product of the control livestock and poultry diarrhea that makes reaches following technical specification:
| Sequence number | Project | Index |
| 1 | Character | Rufous is to brown liquid |
| 2 | PH value | 4.3 |
| 3 | Relative density | 1.03 |
| 4 | Effective ingredient (total flavones) content | 6.6mg/ml |
The extracts of Chinese herbal medicine that adopts said method to make is irritated the piglet that clothes infect epidemic diarrhea according to the consumption of 0.2ml/kg body weight, and on probation through 36 piglets, the result shows: cure 32,3 of being clearly better of symptom, dead 1.
Claims (9)
1. compound Chinese medicinal herb extract of preventing and treating livestock and poultry diarrhea; It is characterized in that being prepared from Flos Paulowniae, Herba Portulacae, Herba polygoni hydropiperis, Herba Erodii, Radix Sanguisorbae, Herba Acalyphae and Radix et Caulis Opuntiae Dillenii, the weight proportion scope of crude drug is: Flos Paulowniae 29-35 part, Herba Portulacae 22-28 part, Herba polygoni hydropiperis 20-26 part, Herba Erodii 17-23 part, Radix Sanguisorbae 17-23 part, Herba Acalyphae 13-17 part and Radix et Caulis Opuntiae Dillenii 8-12 part.
2. the compound Chinese medicinal herb extract of control livestock and poultry diarrhea according to claim 1 is characterized in that the weight proportion of crude drug is: 10 parts of 32 parts of Flos Paulowniaes, 25 parts of Herba Portulacaes, 23 parts of Herba polygoni hydropiperis, 20 parts of Herba Erodiis, 20 parts of Radix Sanguisorbaes, 15 parts of Herba Acalyphaes and Radix et Caulis Opuntiae Dilleniis.
3. the compound Chinese medicinal herb extract of control livestock and poultry diarrhea according to claim 1 is characterized in that the weight proportion of crude drug is: Flos Paulowniae 29kg, Herba Portulacae 22kg, Herba polygoni hydropiperis 20kg, Herba Erodii 17kg part, Radix Sanguisorbae 17kg, Herba Acalyphae 13kg part and Radix et Caulis Opuntiae Dillenii 8kg.
4. the compound Chinese medicinal herb extract of control livestock and poultry diarrhea according to claim 1 is characterized in that the weight proportion of crude drug is: Flos Paulowniae 35kg, Herba Portulacae 28kg, Herba polygoni hydropiperis 26kg, Herba Erodii 23kg, Radix Sanguisorbae 23kg, Herba Acalyphae 17kg and Radix et Caulis Opuntiae Dillenii 12kg.
5. the compound Chinese medicinal herb extract of control livestock and poultry diarrhea according to claim 1 is characterized in that the weight proportion of crude drug is: Flos Paulowniae 32kg, Herba Portulacae 25kg, Herba polygoni hydropiperis 23kg, Herba Erodii 20kg, Radix Sanguisorbae 20kg, Herba Acalyphae 15kg and Radix et Caulis Opuntiae Dillenii 10kg.
6. the compound Chinese medicinal herb extract of control livestock and poultry diarrhea according to claim 1; It is characterized in that the compound Chinese medicinal herb extract finished product is that rufous is to brown liquid; PH value is 4.0～5.0, and relative density is 1.02～1.08, effective ingredient general flavone content >=6.6mg/ml.
7. the compound Chinese medicinal herb extract of control livestock and poultry diarrhea according to claim 5 is characterized in that compound Chinese medicinal herb extract finished product pH value is 4.7, and relative density is 1.03, and the effective ingredient general flavone content is 6.8mg/ml.
8. the compound Chinese medicinal herb extract of control livestock and poultry diarrhea according to claim 3 is characterized in that compound Chinese medicinal herb extract finished product pH value is 4.8, and relative density is 1.05, and the effective ingredient general flavone content is 7.1mg/ml.
9. the compound Chinese medicinal herb extract of control livestock and poultry diarrhea according to claim 4 is characterized in that compound Chinese medicinal herb extract finished product pH value is 4.3, and relative density is 1.03, and the effective ingredient general flavone content is 6.6mg/ml.
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| CN109512934A (en) * | 2017-09-20 | 2019-03-26 | 扬中牧乐药业有限公司 | A kind of oral solution and preparation method thereof for treating swine enteritis |
| CN107551042B (en) * | 2017-09-26 | 2021-01-05 | 葛洪伟 | Traditional Chinese medicine preparation for preventing and treating chicken salmonella diseases and preparation method and use method thereof |
| CN113679768A (en) * | 2021-09-11 | 2021-11-23 | 山东省农业科学院畜牧兽医研究所 | Compound preparation of humifuse euphorbia herb and radix cynanchi asperoides and application of compound preparation in porcine diarrhea |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1541688A (en) * | 2003-11-04 | 2004-11-03 | 中国人民解放军第二军医大学 | Traditional Chinese medicine preparation for treating nonspecific colonitis and its preparing process |
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2008
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Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1541688A (en) * | 2003-11-04 | 2004-11-03 | 中国人民解放军第二军医大学 | Traditional Chinese medicine preparation for treating nonspecific colonitis and its preparing process |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107334885A (en) * | 2017-07-19 | 2017-11-10 | 江苏乐普生物技术有限公司 | A kind of compound Chinese medicinal herb extract for preventing and treating fowl bacterial enteritis |
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| Publication number | Publication date |
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| CN101385803A (en) | 2009-03-18 |
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