CN101367859A - 脂肪酸胆汁酸偶合物及其医药用途 - Google Patents
脂肪酸胆汁酸偶合物及其医药用途 Download PDFInfo
- Publication number
- CN101367859A CN101367859A CNA2007101436855A CN200710143685A CN101367859A CN 101367859 A CN101367859 A CN 101367859A CN A2007101436855 A CNA2007101436855 A CN A2007101436855A CN 200710143685 A CN200710143685 A CN 200710143685A CN 101367859 A CN101367859 A CN 101367859A
- Authority
- CN
- China
- Prior art keywords
- methionin
- acid
- acyl
- compound
- ursodeoxycholic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
Abstract
Description
Claims (9)
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN2007101436855A CN101367859B (zh) | 2007-08-17 | 2007-08-17 | 脂肪酸胆汁酸偶合物及其医药用途 |
PCT/CN2008/001460 WO2009024022A1 (fr) | 2007-08-17 | 2008-08-13 | Conjugués acides gras-acides biliaires et leurs utilisations médicales |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN2007101436855A CN101367859B (zh) | 2007-08-17 | 2007-08-17 | 脂肪酸胆汁酸偶合物及其医药用途 |
Publications (2)
Publication Number | Publication Date |
---|---|
CN101367859A true CN101367859A (zh) | 2009-02-18 |
CN101367859B CN101367859B (zh) | 2011-05-11 |
Family
ID=40377820
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN2007101436855A Expired - Fee Related CN101367859B (zh) | 2007-08-17 | 2007-08-17 | 脂肪酸胆汁酸偶合物及其医药用途 |
Country Status (2)
Country | Link |
---|---|
CN (1) | CN101367859B (zh) |
WO (1) | WO2009024022A1 (zh) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN104610415A (zh) * | 2014-11-13 | 2015-05-13 | 昆明贵金属研究所 | 肝靶向铂类抗癌药物及其合成方法 |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP3004132A4 (en) | 2013-06-06 | 2017-01-18 | Yissum, Research Development Company of the Hebrew | Bile acid-basic amino acid conjugates and uses thereof |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3930696A1 (de) * | 1989-09-14 | 1991-03-28 | Hoechst Ag | Gallensaeurederivate, verfahren zu ihrer herstellung, verwendung als arzneimittel |
IL123998A (en) * | 1998-04-08 | 2004-09-27 | Galmed Int Ltd | Conjugates of bile salts and pharmaceutical preparations containing them |
CN100513415C (zh) * | 2005-08-03 | 2009-07-15 | 中国人民解放军军事医学科学院毒物药物研究所 | 胆汁酸衍生物及其医药用途 |
-
2007
- 2007-08-17 CN CN2007101436855A patent/CN101367859B/zh not_active Expired - Fee Related
-
2008
- 2008-08-13 WO PCT/CN2008/001460 patent/WO2009024022A1/zh unknown
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN104610415A (zh) * | 2014-11-13 | 2015-05-13 | 昆明贵金属研究所 | 肝靶向铂类抗癌药物及其合成方法 |
Also Published As
Publication number | Publication date |
---|---|
WO2009024022A1 (fr) | 2009-02-26 |
CN101367859B (zh) | 2011-05-11 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
C06 | Publication | ||
PB01 | Publication | ||
C10 | Entry into substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
C14 | Grant of patent or utility model | ||
GR01 | Patent grant | ||
C53 | Correction of patent of invention or patent application | ||
CB03 | Change of inventor or designer information |
Inventor after: Zhong Bohua Inventor after: Li Wenbo Inventor after: He Xinhua Inventor after: Chen Lanfu Inventor after: Shi Weiguo Inventor after: Zhang Zhenqing Inventor after: Xie Jianwei Inventor before: Zhong Bohua Inventor before: Li Wenbo Inventor before: He Xinhua Inventor before: Chen Lanfu |
|
COR | Change of bibliographic data |
Free format text: CORRECT: INVENTOR; FROM: ZHONG BOHUA LI WENBO HE XINHUA CHEN LANFU TO: ZHONG BOHUA LI WENBO HE XINHUA CHEN LANFU SHI WEIGUO ZHANG ZHENQING XIE JIANWEI |
|
CF01 | Termination of patent right due to non-payment of annual fee | ||
CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20110511 Termination date: 20210817 |