CN101352336A - Long time dynamic cardiac electric recording apparatus an with sport information acquisition - Google Patents

Long time dynamic cardiac electric recording apparatus an with sport information acquisition Download PDF

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Publication number
CN101352336A
CN101352336A CNA2008100700747A CN200810070074A CN101352336A CN 101352336 A CN101352336 A CN 101352336A CN A2008100700747 A CNA2008100700747 A CN A2008100700747A CN 200810070074 A CN200810070074 A CN 200810070074A CN 101352336 A CN101352336 A CN 101352336A
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circuit
motion
cardiographic
electro
acquiring module
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罗小刚
张焱
李轩
彭承琳
侯长军
霍丹群
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Chongqing University
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Chongqing University
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Abstract

The invention provides a long-time dynamic electro-cardiographic recording device with a motion information collecting function, consisting of an electro-cardiographic signal collecting module, a motion quantity collecting module, a multi-path switch, an A/D conversion circuit, a singlechip, a keyboard and display unit interface, a clock circuit, a Flash card, a communication unit and an upper PC machine. The long-time dynamic electro-cardiographic recording device can carry out the monitoring of motion information and electro-cardiographic signals of freely motioned patient in all-day (24 hours), and provide the synchronous motion information and the electro-cardiographic information when the data is replayed. The long-time dynamic electro-cardiographic recording device adopts a motion sensor to automatically record the motion state of the tested patient; under the control of the singlechip, the motion signal collected by the motion sensor can be synchronously recorded with the electro-cardiographic signal of the patient and memorized in the memory card; the motion signal and the electro-cardiographic signal are exactly corresponding to each other on time, with the precision of millisecond grade; the system analysis software at the post-period has motion analysis function and automatically analyse the signals input by the motion sensor.

Description

A kind of long time dynamic cardiac electric recording apparatus with motion information acquisition
Technical field
The present invention relates to a kind of long time dynamic cardiac electric monitor technology, be specifically related to a kind of long time dynamic cardiac electric recording apparatus with motion information acquisition.Belong to the medical monitoring instrument.
Background technology
Clinical medicine is in the paroxysmal heart disease diagnosis process, adopt long time dynamic cardiac electric recording system (Holter) to write down the electrocardiosignal of (being generally 24 hours) in patient's a period of time, on the ambulatory ecg signal basis that analysis is write down patient's the state of an illness being made judgement by the doctor then, is a kind of sophisticated heart disease diagnosis means.But, but existed an insurmountable problem since midium or long term in this process at present, exactly the myocardial ischemia and the organic myocardial ischemia of how right area componental movement? this is because normal individual for heart, when quantity of motion is big, as skelp, under the situation of high intensity exercises such as stair climbing, because the emergency reaction of human body, reasons such as cardiac function deposit, also cardiac blood supply deficiency can appear, on electrocardiogram, show the phenomenon that the ST section is forced down, this electrocardiogram with have the ST section of cardiopathic individuality to force down comparing class seemingly, therefore, give clinically Electrocardiographic interpretation and make a definite diagnosis and brought certain interference, cause mistaken diagnosis easily.
Eliminate this mistaken diagnosis, by patient the motion conditions of wearing in the Holter process is kept a diary clinically at present, the post survey that is aided with the doctor is then ask to examine and is rejected.Yet this method is subjected to patient's the influence of educational level, responsibility and custom etc. bigger, has very many subjective factorss.The heart per minute produces 70~80 electrocardio wave groups, and the time precision of this manual type record is relatively poor, is difficult to accomplish motion conditions and the electrocardio wave group accurate correspondence on writing time, far can not satisfy the requirement of clinical diagnosis.
Summary of the invention
At the prior art above shortcomings, the object of the present invention is to provide real-time synchronous monitoring patient's movable information of a kind of energy and Electrocardiographic device, movable information and electrocardiosignal to the movable patient of freedom are carried out 24 hours monitoring of whole day, and the long time dynamic cardiac electric recording apparatus of the information of being synchronized with the movement and ecg information is provided when data readback.
The object of the present invention is achieved like this: a kind of long time dynamic cardiac electric recording apparatus with motion information acquisition, it is characterized in that this device comprises ecg signal acquiring module, quantity of motion acquisition module, variable connector, A/D change-over circuit, single-chip microcomputer, keyboard and display unit interface, clock circuit, Flash card, communication unit and upper PC;
Wherein, the ecg signal acquiring module comprises the device that leads, pre-process circuit, pre-amplification circuit, main amplifying circuit, low-pass filter circuit, high-pass filtering circuit and 50Hz trap circuit, and this module is used to gather the electrocardiosignal of human body;
The motor message acquisition module is made up of three dimension acceleration sensor, pre-amplification circuit and filter circuit; Three acceleration transducers are combined into a three dimension acceleration sensor orthogonally, and this module is used to measure the motor message of human body;
Variable connector is used for quick switch sampling passage;
The A/D change-over circuit, the analog electrocardiogram and the motor message that are used for collecting convert digital signal to;
Single-chip microcomputer is mainly used in the work of control circuit, and with the signal storage that collects in the Flash card;
Keyboard and display unit interface are used to provide man machine interface;
Clock circuit is used to single-chip microcomputer that clock accurately is provided, be convenient to motor message in electrocardiosignal synchronously;
The Flash card is used to store ecg information and movable information;
Communication unit is used for communicating by letter of single-chip microcomputer and upper PC.
This device is under the control of single-chip microcomputer, the electrocardiosignal of human body is gathered by the ecg signal acquiring module, be sent to through the multipath high-speed electrical switch with the signal that is synchronized with the movement of motor message acquisition module collection and carry out analog digital conversion in the A/D converter, and will change good digital signal and deposit in the Flash card, and be presented on the LCD display synchronously; Single-chip microcomputer is controlled the gating of A/D conversion and variable connector, the collection of realization multichannel synchronizing signal respectively by system's timesharing in this process.
Compared to existing technology, the present invention has following characteristics:
1, adopt motion sensor to write down experimenter's kinestate automatically, the motor message that motion sensor is gathered and patient's electrocardiosignal are under the control of single-chip microcomputer, carry out synchronous recording and be stored on the storage card, both are accurately corresponding in time, and precision can reach Millisecond.
2, systematic analysis software has the motion analysis function, can be automatically analyze the motor message of motion sensor input, extract wherein such as movable informations such as merit amount, motion frequency and amplitudes.
3, can correctly use long time dynamic cardiac electric recording system (Holter) come right area componental movement myocardial ischemia and organic myocardial ischemia can be in patient worn Holter process accurate measurement patient quantity of motion, patient's electrocardiogram is corresponding with motion conditions, thereby solve the deficiency of present clinical Holter in the interpretation of ST section, eliminate mistaken diagnosis myocardial ischemia.
4, the present invention can carry out 24 hours monitoring of whole day to the active patient of freedom, real-time movable information and the synchronous data of electrocardio is provided, can patient directions carry out an amount of motion, improve cardiovascular diseases's positive rate and patient is safe from danger, provide abundanter data for treating and study cardiovascular disease.
Description of drawings
Fig. 1 is a system structure functional-block diagram of the present invention;
Fig. 2 is a data collection task flow chart of the present invention;
Fig. 3 is the scheme of installation of three dimension acceleration sensor;
Fig. 4 is the structure chart of motor message acquisition module;
Fig. 5 is a kind of pre-process circuit of ecg signal acquiring module;
Fig. 6 is a kind of pre-amplification circuit of ecg signal acquiring module;
Fig. 7 is a kind of main amplifying circuit and low pass filter of ecg signal acquiring module;
Fig. 8 is a kind of 50Hz trap circuit of ecg signal acquiring module;
Fig. 9 A is that a kind of ST section changes collection of illustrative plates;
Fig. 9 B is the acceleration change collection of illustrative plates of Fig. 9 A;
Figure 10 A is that another kind of ST section changes collection of illustrative plates;
Figure 10 B is the synchronous acceleration change collection of illustrative plates of Figure 10 A.
The specific embodiment
As shown in Figure 1, a kind of long time dynamic cardiac electric recording apparatus provided by the present invention with motion information acquisition, this device core comprises ecg signal acquiring module, motor message acquisition module, variable connector, A/D change-over circuit, single-chip microcomputer, keyboard and display unit interface, clock circuit, Flash card, communication unit and upper PC; Also comprise conventional components such as the power circuit that adopts existing mature technology and shell,, also omit among the figure this tired stating.
Wherein, (1) ecg signal acquiring module partly is made up of the device that leads, pre-process circuit, pre-amplification circuit, main amplifying circuit, low-pass filter circuit, high-pass filtering circuit and 50Hz trap circuit etc.
The device that leads of ecg signal acquiring module improves limb lead by Mason-Likar and the Wilson resistor network is formed, and accepts the electrocardiosignal from crosslinking electrode.The pre-process circuit of ecg signal acquiring module is made up of operational amplifier A and resistance R 1 as shown in Figure 5, and its effect is to improve input impedance, reduces output impedance, plays a cushioning effect.
The pre-amplification circuit of ecg signal acquiring module is formed amplification A=1+49.4k/Rg by instrumentation amplifier AD620 and resistance R g as shown in Figure 6.This preamplifier has high cmrr, high input impedance, and noise is little, the characteristics that capacity of resisting disturbance is strong.Wherein, 49.4k is a constant, and k represents 1000, is resistance expression way commonly used.
The main amplifying circuit of ecg signal acquiring module and low pass filter as shown in Figure 7, by operational amplifier A and resistance R 1, R2, R3 and capacitor C 1 formed, corner frequency is set in 160Hz, amplification A=1+R2/R1.
The high pass filter of ecg signal acquiring module is used for the interference of filtering low frequency signal, adopts single order RC high-pass filtering circuit, and corner frequency is set in 0.07Hz.
The 50Hz trap circuit of ecg signal acquiring module is a band elimination filter, is mainly used in the filtering power frequency and disturbs.Two operational amplifier A, B and three resistance R 1, R2, R3 and three typical twin-T networks that capacitor C 1, C2, C3 form have been adopted, as shown in Figure 8.
(2) the motor message acquisition module is made up of acceleration transducer, pre-amplification circuit and filter circuit.
The acceleration transducer of motor message acquisition module is used to measure motor message, adopts 3031, three acceleration transducers of resistance pressure type acceleration transducer of IC SENSOR company to be combined into a three dimension acceleration sensor orthogonally.Its mounting means such as Fig. 3.The pre-amplification circuit of motor message acquisition module adopts the structure identical with the pre-amplification circuit of ecg signal acquiring module.The filter circuit of described motor message acquisition module is a low-pass filter circuit, is used to suppress the High-frequency Interference that produced by circuit, adopts single order RC low-pass filter circuit, and corner frequency is set in 20Hz.
(3) variable connector is used for quick switch sampling passage, can adopt CD4051.
(4) A/D change-over circuit, the analog electrocardiogram and the motor message that are used for collecting convert digital signal to, can adopt modulus conversion chip MAX197, and sample rate is 100ksps, and sampling precision is 12.
(5) single-chip microcomputer is mainly used in the work of control circuit, and with the signal storage that collects in the Flash card, adopt the MSP430 series monolithic.
(6) keyboard and display unit interface are used to provide man machine interface.
(7) clock circuit is used to single-chip microcomputer that clock accurately is provided, be convenient to motor message in electrocardiosignal synchronously, adopt clock chip DS1302.
(8) the Flash card is used to store electrocardio and movable information, adopts known commercially available prod.
(9) communication unit is used for communicating by letter of single-chip microcomputer and upper PC, adopts the usb communication circuit.
System works flow process of the present invention is as follows: under the control of single-chip microcomputer, the electrocardiosignal of human body is gathered by the ecg signal acquiring module, be sent to through the multipath high-speed electrical switch with the signal that is synchronized with the movement of motor message acquisition module collection and carry out analog digital conversion in the A/D converter, and will change good digital signal and deposit in the Flash card, and be presented on the LCD display synchronously.Single-chip microcomputer is controlled the gating of A/D conversion and variable connector, the collection of realization multichannel synchronizing signal respectively by system's timesharing in this process.Data collection task flow process of the present invention is referring to Fig. 2.After once finishing using, the Flash card of extraction system is also put into card reader and is connected on computers, and electrocardiosignal and the motor message preserved on the Flash card are read in and analyzed by upper computer software.
The electrocardio signal acquisition module that is synchronized with the movement is made of acceleration transducer, preamplifier, filter circuit.For native system, because the effective range of human motion acceleration signal is-6g~6g, 0Hz~20Hz must meet this effective range when selecting acceleration transducer.In order more intactly to reflect the motion conditions of human body, three dimension acceleration sensor is more suitable than one-dimensional acceleration transducer simultaneously, and the former can gather the three-dimensional motion information of human body.Native system adopts the resistance pressure type acceleration transducer 3031 of three IC SENSOR companies to be combined into a three dimension acceleration sensor orthogonally.3031 adopt the surface encapsulation form, and its size is little, and Adjustable Damping, and bandwidth are highly sensitive, built-in vibration abatement.The mounting means of three dimension acceleration sensor is referring to shown in Figure 3.
The structure of motor message acquisition module is referring to shown in Figure 4, the acceleration transducer that X, Y and Z direction are placed is corresponding one road pre-amplification circuit respectively, the acceleration of motion signal is sent into filter circuit and is carried out filtering after pre-amplification circuit amplifies, High-frequency Interference in the filtered signal, the wave filter upper cut-off frequency is set at 20Hz.Filtered three road motor messages link to each other with the variable connector of numerical portion, carry out gating by Single-chip Controlling, read the motor message data on this direction.
In the Flash card that synchronous electrocardiosignal after synchronous and post processing: the A/D conversion of motor message and electrocardiosignal and motor message are stored in system, in a use, after finishing patient data's collecting work, the doctor takes out the Flash card, inserts on the inherent computer of card reader and carries out playback.Because electrocardiosignal and motor message are deposited in order, are the physiological parameter information that is write down under the synchronization in electrocardiosignal of reading on the adjacent memory address and motor message data then, they are strict corresponding on time shaft.
Data acquisition time calculates by following formula:
τ=τ 0+n*1/f (1)
τ is a data acquisition time to be asked in the formula, and unit is s; N is the position of electrocardiosignal (or motor message parameter) on data sequence; τ 0Be the time of beginning data record, unit is s; F is the frequency of data sampling, and unit is Hz.After setting up coordinate unified time by formula (1), just can carry out motor message and electrocardiosignal to depict in the coordinate at the same time synchronously, when the abnormal electrocardiogram incident occurring, the doctor can inquire about corresponding kinematic parameter, thereby makes correct diagnosis like this.Patient's motion cumulant is calculated by formula (2), (3), (4), (5):
W x = 0.0216 * ∫ τ 0 τ a x dτ + 1.3 - - - ( 2 )
W y = 0.0216 * ∫ τ 0 τ a y dτ + 1.3 - - - ( 3 )
W z = 0.0216 * ∫ τ 0 τ a z dτ + 1.3 - - - ( 4 )
W=W x+W y+W z (5)
Wherein, W is motion accumulation merit amount, and unit is J/skg; a x, a y, a zBe respectively the acceleration that the counterparty makes progress, unit is m/s 2W x, W y, W zBe respectively the motion accumulation merit amount that the counterparty upwards calculates.
Be that one section absolute ST of maximum changes collection of illustrative plates shown in Fig. 9 A, on behalf of the ST section, Fig. 9 A vertical coordinate change amplitude, and unit is mv, abscissa does not have indexing, because be one section that intercepts in 24 hour datas, abscissa is represented the time, Fig. 9 B vertical coordinate is represented comprehensive acceleration, the m/s of unit 2, abscissa representative and synchronous time of Fig. 9 A.Each data of ST section amplitude of variation all are the differences of ST section current potential and zero potential on this time point.In traditional Holter diagnostic system, just being difficult to distinguish when the doctor runs into this situation is mobility's myocardial ischemia or organic myocardial ischemia, if but synchronous movable information is arranged, just can determine very soon.Shown in Fig. 9 B, it is the information that the is synchronized with the movement acceleration change collection of illustrative plates of Fig. 9 A, as can be seen from Figure, increase along with acceleration, the ST section is forced down and is occurred increasing, and along with reducing of acceleration, the ST section is forced down and occurred reducing, thereby can judge because kinetic ST section is forced down, then can judge it is mobility's myocardial ischemia.Figure 10 A and Figure 10 B are that the absolute ST of other one section maximum changes collection of illustrative plates and synchronous acceleration change collection of illustrative plates, as can be seen from the figure when the ST section occurring and force down, acceleration does not have significant change, illustrates not to be because kinetic ST section is forced down, thereby can judge it is organic myocardial ischemia.Therefore, had after the synchronous movable information, just can solve the deficiency of present clinical Holter in the interpretation of ST section, eliminated mistaken diagnosis myocardial ischemia.
The present invention carries out the A/D conversion with motor message and electrocardiosignal that the same time collects in sampling process, their interval is equal to the interval of an A/D conversion, and therefore, precision can reach Millisecond.This device is used to gather synchronous motor message and electrocardiosignal, and utilizes this synchronizing signal difference mobility's myocardial ischemia and organic myocardial ischemia, thereby eliminates the mistaken diagnosis to myocardial ischemia.

Claims (3)

1. long time dynamic cardiac electric recording apparatus with motion information acquisition, it is characterized in that this device comprises ecg signal acquiring module, quantity of motion acquisition module, variable connector, A/D change-over circuit, single-chip microcomputer, keyboard and display unit interface, clock circuit, Flash card and communication unit and upper PC;
The ecg signal acquiring module, this module is used to gather the electrocardiosignal of human body; It comprises the device that leads, pre-process circuit, pre-amplification circuit, main amplifying circuit, low-pass filter circuit, high-pass filtering circuit and 50Hz trap circuit;
The motor message acquisition module is made up of acceleration transducer, pre-amplification circuit and filter circuit; Three acceleration transducers are combined into a three dimension acceleration sensor orthogonally, and this module is used to measure the motor message of human body;
Variable connector is used for quick switch sampling passage;
The A/D change-over circuit, the analog electrocardiogram and the motor message that are used for collecting convert digital signal to;
Single-chip microcomputer is mainly used in the work of control circuit, and with the signal storage that collects in the Flash card;
Keyboard and display unit interface are used to provide man machine interface;
Clock circuit is used to single-chip microcomputer that clock accurately is provided, be convenient to motor message in electrocardiosignal synchronously;
The Flash card is used to store electrocardio and movable information;
Communication unit is used for communicating by letter of single-chip microcomputer and upper PC;
This device is under the control of single-chip microcomputer, the electrocardiosignal of human body is gathered by the ecg signal acquiring module, be sent to through the multipath high-speed electrical switch with the signal that is synchronized with the movement of motor message acquisition module collection and carry out analog digital conversion in the A/D converter, and will change good digital signal and deposit in the Flash card, and be presented on the LCD display synchronously; Single-chip microcomputer is controlled the gating of A/D conversion and variable connector, the collection of realization multichannel synchronizing signal respectively by system's timesharing in this process.
2. a kind of long time dynamic cardiac electric recording apparatus according to claim 1 with motion information acquisition, it is characterized in that, the device that leads of described ecg signal acquiring module, form by Mason-Likar improvement limb lead and Wilson resistor network, accept electrocardiosignal from crosslinking electrode;
The pre-process circuit of ecg signal acquiring module is made up of operational amplifier A and R1, is used to improve input impedance, reduces output impedance;
The pre-amplification circuit of ecg signal acquiring module is formed amplification A=1+49.4k/Rg by instrumentation amplifier AD620 and resistance R g;
The main amplifying circuit of ecg signal acquiring module and low pass filter, by operational amplifier A and resistance R 1, R2, R3 and capacitor C 1 are formed, and corner frequency is set in 160Hz, amplification A=1+R2/R1;
The high pass filter of ecg signal acquiring module is used for the interference of filtering low frequency signal, adopts single order RC high-pass filtering circuit, and corner frequency is set in 0.07Hz;
The 50Hz trap circuit of ecg signal acquiring module is a band elimination filter, is mainly used in the filtering power frequency and disturbs; Adopted two operational amplifier A, B and three resistance R 1, R2, R3 and three capacitor C 1, C2, C3 to form twin-T network.
3. a kind of long time dynamic cardiac electric recording apparatus according to claim 1 with motion information acquisition, it is characterized in that, this device is used to gather synchronous motor message and electrocardiosignal, and utilizes this synchronizing signal difference mobility's myocardial ischemia and organic myocardial ischemia.
CNA2008100700747A 2008-08-01 2008-08-01 Long time dynamic cardiac electric recording apparatus an with sport information acquisition Pending CN101352336A (en)

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Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101596100B (en) * 2009-07-01 2011-07-20 北京派瑞根科技开发有限公司 Paroxysmal disease analysis system based on motion sensor and biosensor
CN101721206B (en) * 2009-12-11 2011-08-03 无锡市吉天通信科技有限公司 Dynamic electrocardiograph with human motion state and posture detection function
CN102166119A (en) * 2011-03-29 2011-08-31 东北大学 Single-arm type electrocardio auxiliary fall detector
CN102551730A (en) * 2011-12-15 2012-07-11 无锡市仁科医疗电子有限公司 Device for simulating actions of abdominal wall surface and simulation method thereof
CN102944697A (en) * 2012-11-06 2013-02-27 昆山北极光电子科技有限公司 Three-dimensional coordinate acceleration measuring circuit
CN106037718A (en) * 2016-07-08 2016-10-26 莲康科技有限公司 Wearable electrocardiogram system
CN106510696A (en) * 2016-12-22 2017-03-22 蓝色传感(北京)科技有限公司 Active noise control digital electrode collecting system and collecting method thereof
CN109199374A (en) * 2018-10-15 2019-01-15 烟台羿中医疗科技有限公司 A kind of multi-lead electrocardiogram (ECG) data recording device and method
CN110811599A (en) * 2019-11-19 2020-02-21 北京东方逸腾数码医疗设备技术有限公司 Signal synchronous acquisition system
CN111772626A (en) * 2020-07-06 2020-10-16 华中科技大学 Electrocardiogram recording module based on big data algorithm

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101596100B (en) * 2009-07-01 2011-07-20 北京派瑞根科技开发有限公司 Paroxysmal disease analysis system based on motion sensor and biosensor
CN101721206B (en) * 2009-12-11 2011-08-03 无锡市吉天通信科技有限公司 Dynamic electrocardiograph with human motion state and posture detection function
CN102166119A (en) * 2011-03-29 2011-08-31 东北大学 Single-arm type electrocardio auxiliary fall detector
CN102166119B (en) * 2011-03-29 2012-07-18 东北大学 Single-arm type electrocardio auxiliary fall detector
CN102551730A (en) * 2011-12-15 2012-07-11 无锡市仁科医疗电子有限公司 Device for simulating actions of abdominal wall surface and simulation method thereof
CN102944697A (en) * 2012-11-06 2013-02-27 昆山北极光电子科技有限公司 Three-dimensional coordinate acceleration measuring circuit
CN106037718A (en) * 2016-07-08 2016-10-26 莲康科技有限公司 Wearable electrocardiogram system
CN106510696A (en) * 2016-12-22 2017-03-22 蓝色传感(北京)科技有限公司 Active noise control digital electrode collecting system and collecting method thereof
CN109199374A (en) * 2018-10-15 2019-01-15 烟台羿中医疗科技有限公司 A kind of multi-lead electrocardiogram (ECG) data recording device and method
CN110811599A (en) * 2019-11-19 2020-02-21 北京东方逸腾数码医疗设备技术有限公司 Signal synchronous acquisition system
CN111772626A (en) * 2020-07-06 2020-10-16 华中科技大学 Electrocardiogram recording module based on big data algorithm

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