CN101288669A

CN101288669A - Exterior-applied powder for treating pressure sore

Info

Publication number: CN101288669A
Application number: CNA2008100164557A
Authority: CN
Inventors: 陈铭; 许慧
Original assignee: Individual
Current assignee: Individual
Priority date: 2008-06-02
Filing date: 2008-06-02
Publication date: 2008-10-22

Abstract

A powdered drug for treating pressure sore through external application belongs to an external western medicine preparation, which mainly solves the problem of pressure sore treatment. Raw materials for preparing effective components of the powdered drug comprise the following weight parts: 1-10 parts of sulfamethoxazole compound, 1-10 parts of metronidazole, 5-50 parts of Vitamin C, 5-50 parts of vitamin B complex, 5-50 parts of nicotinic acid, 3-15 parts of egg shell inner membrane dried by excipients. When in use, a mackintosh, a plurality of sterilized dressings and a sterilized dressing bag are padded under the part with pressure sore; the sore surface is repeatedly washed from top to bottom with 0.9 percent physiological saline extracted with a disposable sterilized syringe until the wound is clean and then is washed from top to bottom for twice to three times with 0.1 percent chlorhexidine solution; when blisters are formed, a disposable sterilized syringe is used for drawing out the liquid in the blisters; when necrotic tissues are formed, the necrotic tissues are eliminated with sterile forceps and sterile shears, then repeated washing from top to bottom with 0.1 percent chlorhexidine solution is carried out until the sore surface is clean, and then the prepared powdered drug is evenly sprinkled on the sore surface by a sterilized cotton bud; the thickness of the powdered drug is about 1mm; finally the sore surface is covered with sterilized petroleum jelly gauze and bandaged with sterilized dressing; the drug is changed once a day to prevent local compression. When new granulation tissue outgrows, the sore surface is scattered with drug powder without dressing, and the drug powder self drops off after scab is formed until the sore is healed. The powdered drug has simple and convenient preparation method, abundant drug resources, low cost, convenient and simple clinical application and remarkable effect, which is deeply welcomed by broad patients.

Description

A kind of medicine powder of externally treating pressure ulcer

Technical field

The present invention relates to a kind of external Western medicine preparation, be specially a kind of medicine powder of externally treating pressure ulcer.

Background technology

Pressure ulcer is common clinically a kind of complication, the patient of particularly oldaged physically weak, prolonged illness bed, stupor, paralysis, because of long-term bed, the part is the pressurized disturbance of blood circulation repeatedly, cause the hypoxic-ischemic skin ulceration to form ulcer, can not heal for a long time as untimely treatment, patient's pain unbearably, or ulcer surface enlarges and deepen, and easily causes septicemia and jeopardizes patient's life.

At present, the treatment pressure ulcer have that bearing hydrocolloid dressing such as medicine film paste, ulcer pastes lid, also have asepticly change dressings, heating therapy etc., therapeutic effect more slowly, all undesirable.For seeking a kind of medicine powder of ideal treatment pressure ulcer, we have carried out clinical experiment for many years, have developed this medicine powder, and have obtained better therapeutic effect.

Summary of the invention

The objective of the invention is to overcome above-mentioned the deficiencies in the prior art, and a kind of medicine powder of externally treating pressure ulcer is provided, can make the healing of pressure ulcer ulcer surface apace, effectively, remove patient's misery.

Technical scheme of the present invention is,

A kind of medicine powder of externally treating pressure ulcer is characterized in that, makes the powder raw materials of effective components by following weight portion to be: bactrim 1-10, metronidazole 1-10, vitamin C 5-50, compound vitamin B 5-50, nicotinic acid 5-50.The Ovum crusta Gallus domesticus inner membrance 3-15 of adjuvant oven dry.

Preparation is during medicated powder, with medicated powder raw material and adjuvant according to required weight part all pulverized 200 mesh sieves be processed into the smalls shape, through infrared sterilization, stand-by after bottled.

Pressure ulcer position underlay is with blanket during application, aseptic dressing several piece and aseptic changing dressings are wrapped 1, extract 0.9% normal saline earlier with disposable sterilized injector, the face of flushing skin ulcer repeatedly from top to bottom is to cleaning, reuse 0.1% is washed than safe solution flushing 2-3 from top to down time, when having vesicle to form, with the liquid in the asepsis injector extraction vesicle, when having slough to form, remove slough with aseptic nipper and aseptic scissors, and reuse 0.1% is washed than the flushing repeatedly from top to down of safe solution to cleaning, the medicated powder that will prepare with disinfecting cotton swab applies uniformly and is sprinkling upon on the skin ulcer face then, and the about 1mm of medicated powder thickness covers back external use sterile dressing wrapping with aseptic petrolatum oil gauze at last, change dressings every day once, prevent local compression.When having new granulation tissue to grow, sprinkle medicated powder, no longer wrapping drops to recovery from illness after the formation incrustation voluntarily.

Pharmacological action

It is broad-spectrum antibacterial medicine that 1 bactrim belongs to sulfa drugs, and gram positive bacteria and gram-negative bacteria are had bacteriostasis.

2 metronidazoles are used for the treatment of anaerobic infection.

3 vitamin Cs participate in the formation of intercellular substance, cause wound, ulcer to heal during shortage.

4 compound vitamin Bs are important composition compositions of multiple coenzyme, involved in sugar, fat, proteinic metabolism, the reparation that helps organizing.

5 nicotinic acid have stronger peripheral vasodilation effect, can strengthen partial blood supply, promote ulcer healing.

Micromicro replenishes protein in 6 Ovum crusta Gallus domesticuss, promotes new raw meat dental tissue hypertrophy, promotes wound healing.

After medicine powder of the present invention mixed said medicine, its drug effect had the coordination complementary action, in the treatment pressure ulcer, had obtained remarkable result.

The invention has the beneficial effects as follows: clinical verification shows:

1, press the about 1-2cm of infections face diameter, have vesicle or vesicle ulceration to expose moist ruddy wound surface, medication 3-5 days wound surface can heal.

2, press the about 2-4cm of infections face diameter, have vesicle or vesicle ulceration to expose moist ruddy wound surface, wound surface has yellow transudate, has pus to cover if any infecting the surface, causes shallow layer tissue's necrosis, formation ulcer, medication 5-12 days, the ulcer surface recovery from illness of can healing.

3, press infections face diameter pact＞4cm, ulcer surface more greatly, darker, pus is more, and slough formation is arranged, medication 18-30 days, the ulcer surface recovery from illness of can healing.

Preparation method of the present invention is easy, and drug resource is abundant, and cost is low, and clinical practice is convenient, simple, and effect is remarkable, is subjected to the welcome of extensive patients deeply.

Example surplus the clinical verification in the past few years 200 has all obtained satisfied effect.Model case is as follows:

Vesicle formed 1 Li Li woman because of the about 2cm pressure ulcer of diameter appears in cerebral hemorrhage stupor, 15 days sacrococcygeal regions of bed in 61 years old, and 3 days wound surface of medication have the thin crust of one deck to form wound healing.

2 kings found the state male 67 years old because of cerebral infarction causes the left limb paralysis, the pressure ulcer that the about 3cm of diameter appearred in left anterior superior iliac spine in 43 days of lying in bed, and vesicle forms the ulceration that also has, 2 days wound surface dryings of medication, 7 days ulcer surfaces of medication have the thin crust of one deck to form wound healing.

The refined virtue woman of 3 Lee 75 years old is because of row hematoma aspiration art, compulsive position, and the pressure ulcer of about 3cm of diameter and 2cm all appears in end afterbody, omoplate portion, and the vesicle ulceration exposes moist ruddy wound surface, medication 3-5 days wound surface dryings, medication 8-12 days wound surface form incrustation and heal.

4 tree English woman 77 years old are surplus because of cerebral hemorrhage right side quadriplegia bed 3 months, patient's obesity, and the pressure ulcer of the about 2cm of about diameter appears in omoplate portion and anterior superior iliac spine, and the vesicle ulceration exposes moist ruddy wound surface, and 7 days wound surface of medication form to form a scab and heal.The pressure ulcer of the about 3cm of diameter appears in end afterbody, and the surface has pus to cover, and shallow layer tissue's necrosis forms ulcer, medication 15 days, and ulcer surface forms the incrustation healing.

5 are prolonged great waves man 69 years old because of Guillain Barre syndrome respirator assisted respiartion bed 76 days, patient's body constitution is relatively poor, resistance a little less than, be subjected to the influence of compulsive position again, the pressure ulcer that the about 3cm of diameter appearred in sacrococcygeal region in 25 days of lying in bed, vesicle forms, medication 8 days, and ulcer surface has the thin crust of one deck to form wound healing.

6 Zhao Jin inscription man was in and lies in bed nearly half a year because of two lower extremity paralysiss behind the cerebral infarction in 82 years old, and the pressure ulcer of 2-3cm all appears in omoplate portion, anterior superior iliac spine, and the surface has pus to cover, and shallow layer tissue's necrosis forms ulcer, and 15 days ulcer surfaces of medication form incrustation and heal.The about 4cm of sacrococcygeal region pressure ulcer diameter, slough is invaded subcutis, medication 30 days, ulcer surface forms the incrustation healing.

The specific embodiment

Example one

A kind of medicine powder of externally treating pressure ulcer is made the powder raw materials of effective components and by following weight portion is: the Ovum crusta Gallus domesticus inner membrance 3 of bactrim 1, metronidazole 1, vitamin C 5, compound vitamin B 5, nicotinic acid 5, adjuvant oven dry.

Preparation is during medicated powder, with the medicated powder raw material according to required weight part all pulverized 200 mesh sieves be processed into the smalls shape, through infrared sterilization, stand-by after bottled.

Example two

A kind of medicine powder of externally treating pressure ulcer is made the powder raw materials of effective components and by following weight portion is: the Ovum crusta Gallus domesticus inner membrance 15 of bactrim 10, metronidazole 10, vitamin C 50, compound vitamin B 50, nicotinic acid 50, adjuvant oven dry.

Preparation method is the same.

Example three

A kind of medicine powder of externally treating pressure ulcer is made the powder raw materials of effective components and by following weight portion is: the Ovum crusta Gallus domesticus inner membrance 10 of bactrim 5, metronidazole 5, Catergen 0, compound vitamin B 20, nicotinic acid 20, adjuvant oven dry.

Preparation method is the same.

Example four

A kind of medicine powder of externally treating pressure ulcer is made the powder raw materials of effective components and by following weight portion is: the Ovum crusta Gallus domesticus inner membrance 7 of bactrim 5, metronidazole 5, vitamin C 30, compound vitamin B 30, nicotinic acid 30, adjuvant oven dry.

Preparation method is the same.

Claims

1, a kind of medicine powder of externally treating pressure ulcer, it is characterized in that, making the powder raw materials of effective components by following weight portion is: bactrim 1-10, metronidazole 1-10, vitamin C 5-50, compound vitamin B 5-50, nicotinic acid 5-50, the Ovum crusta Gallus domesticus inner membrance 3-15 of adjuvant oven dry.