CN101239114A - Medicinal composition for treating liver-depression spleen-deficiency and diarrhea and preparation thereof - Google Patents
Medicinal composition for treating liver-depression spleen-deficiency and diarrhea and preparation thereof Download PDFInfo
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- CN101239114A CN101239114A CNA2008101021141A CN200810102114A CN101239114A CN 101239114 A CN101239114 A CN 101239114A CN A2008101021141 A CNA2008101021141 A CN A2008101021141A CN 200810102114 A CN200810102114 A CN 200810102114A CN 101239114 A CN101239114 A CN 101239114A
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Abstract
The present invention discloses a medicine composition for treating liver-stagnation and spleen-deficiency diarrhea, which is prepared from five Chinese traditional medicines including largehead atractylodes rhizome, white paeony root, tangerine peel, divaricate saposhnikovia root and largetrifoliolious bugbane rhizome. The medicine composition can sooth liver and strengthen spleen, relieve spasm and pain for treating borborygmus diarrhea casued by liver-stagnation and spleen-deficiency, reprievable pain after diarrhea, repeated outbreak, thin white fur of tongue, wiry left pulse but moderate right pulse etc, and above-mentioned symptoms caused by acute-chronic enteritis, bowel irritable syndrome, colonitis and Meniere's syndrome. The medicine composition has the merits of high cure rate, low recurrence rate and wide application value.
Description
Technical field
The present invention relates to a kind of pharmaceutical composition, belong to the technical field of pharmaceuticals for the treatment of liver-depression spleen-deficiency and diarrhea.Be used for the treatment of borborygmus diarrhoea due to the stagnation of liver-QI with deficiency of the spleen, rush down the back pain and reprieve, outbreak repeatedly, thin white fur of tongue, arteries and veins left side string and right slow etc., and acute chronic enteritis, irritable bowel syndrome, colitis and Meniere disease etc.
Background technology
Having loose bowels is to increase with times of defecation, and excrement matter is thin, even to gush as water sample be a kind of common taste enteropathy card of Clinical symptoms, all can take place throughout the year, but comparatively to see in two seasons of autumn in summer more.The Chinese medicine primary disease has curative effect preferably." Required Readings for Medical Professionals is had loose bowels " ruled by men before summary and let out on the empirical basis, propose famous controlling and let out nine methods, be lightly ooze, ascending, refrigerant, dredge sharp, sweet slow, acid receipts, dry spleen, the kidney warming, astringent or styptic treatment for spontaneous sweating, its argumentation system and comprehensively, be the great development on the therapeutics of having loose bowels, its practical value is also confirmed by clinical.Primary disease is found in the multiple disease in the western medicine, as acute chronic enteritis, tuberculosis of intestine, irritable bowel syndrome, malabsorption syndrome etc.
The cause of disease of primary disease is many-sided, mainly contains being invaded by exogenous pathogen, injury due to diet, disorder of emotion, weakness of the spleen and stomach, decline of the fire from the gate of life or the like.These causes of disease cause insufficiency of the spleen leading to overabundance of dampness, dysfunction of the spleen in transportation, and the intestine and small intestine development of evil in febrile disease is not normal, the lifting imbalance, clear QI being mixed up with turbid QI forms and has loose bowels.Having loose bowels that wherein disorder of emotion causes increases gradually along with the social life of high rhythm.The disorder of emotion worry is disgruntled, depression of liver-QI, perverse and unreasonable manner gram spleen, dysfunction of the spleen in transportation, lifting imbalance; Or plain body is insufficiency of the spleen, meets angry feed, and more impairment of the spleen soil causes dysfunction of the spleen in transportation, the lifting imbalance, and clear QI being mixed up with turbid QI forms and has loose bowels.So " Jing Yue's complete work is had loose bowels " say: " all chance anger person that just do not have loose bowels, folder food in the time of must be earlier with anger, the taste of causing injury, so but violate to some extent, promptly with touching and, the dirty disease of this liver spleen two is also.Lid is with the liver Wood restricts earth, the spleen being damaged and right.”
At present for the treatment of having loose bowels based on Western medicine, but Western medicine is bad to the effect of some liver-depression spleen-deficiency and diarrhea particularly of having loose bowels, and the side effect of Western medicine is bigger.So it is imperative to invent a kind of Chinese patent medicine for the treatment of liver-depression spleen-deficiency and diarrhea.
Summary of the invention
The objective of the invention is to overcome the weak point on the treatment liver-depression spleen-deficiency and diarrhea at present, and a kind of evident in efficacy, convenience of drawing materials, the pharmaceutical composition of the treatment liver-depression spleen-deficiency and diarrhea that expense is cheap, side effect is little are provided.
The present invention also provides this preparation method of Chinese medicine.
Pharmaceutical composition of the present invention can be used for borborygmus diarrhoea due to the stagnation of liver-QI with deficiency of the spleen, rushes down the back pain and reprieves, outbreak repeatedly, thin white fur of tongue, arteries and veins left side string and right slow etc., and acute chronic enteritis, irritable bowel syndrome, colitis and Meniere disease.
Chinese medicine of the present invention is prepared from by the following weight parts proportion raw material:
30~90 parts of 20~60 parts of Radix Saposhnikoviaes of 30~90 parts of Pericarpium Citri Reticulataes of 45~135 portions of Radix Paeoniae Albas of the Rhizoma Atractylodis Macrocephalae
9~27 parts of Rhizoma Cimicifugaes
Chinese medicine of the present invention is prepared from by the following weight parts proportion raw material:
50~70 parts of 40~50 parts of Radix Saposhnikoviaes of 50~70 parts of Pericarpium Citri Reticulataes of 80~100 portions of Radix Paeoniae Albas of the Rhizoma Atractylodis Macrocephalae
15~20 parts of Rhizoma Cimicifugaes
Chinese medicine of the present invention is prepared from by following optimum weight part proportion raw material:
18 parts of 60 parts of Rhizoma Cimicifugaes of 45 parts of Radix Saposhnikoviaes of 60 parts of Pericarpium Citri Reticulataes of 90 portions of Radix Paeoniae Albas of the Rhizoma Atractylodis Macrocephalae
Chinese medicine of the present invention can be prepared from by following method:
1, the Rhizoma Atractylodis Macrocephalae, Pericarpium Citri Reticulatae, Radix Saposhnikoviae, the Radix Paeoniae Alba are extracted volatile oil.
2, a medicinal residues and Rhizoma Cimicifugae merging times decocting boils twice, concentrates spraying, drying.
3, volatile oil sprays into, encapsulated getting final product.
The wherein said Rhizoma Atractylodis Macrocephalae is the dry rhizome of feverfew Rhizoma Atractylodis Macrocephalae Atractylodes macrocephala Koidz..Main product in Zhejiang, ground such as Hunan, Hubei, Hebei, Shandong.With Rhizoma Atractylodis Macrocephalae (parched with earth) is good.
The Radix Paeoniae Alba is the dry root of cohosh Radix Paeoniae Paeonia lactiflora Pall..Main product in Zhejiang, ground such as Sichuan, Anhui.With Radix Paeoniae Alba (parched) is good.
Pericarpium Citri Reticulatae is the dry mature skin of rutaceae orange Citrus reticulata Blanco. and variety thereof.Main product in Guangdong, ground such as Guangxi, Fujian, Jiangxi.To fry Pericarpium Citri Reticulatae is good.
Radix Saposhnikoviae is the dry root of umbelliferae Saposhnikovia divaricata Saposhnikovia divaricata (Turcz.) Schischk..Main product in Heilungkiang, Jilin, the Inner Mongol, Hebei.
Rhizoma Cimicifugae is the dry rhizome for the big SANYE Rhizoma Cimicifugae of ranunculaceae plant Cimicifuga heracleifolia Kom., Rhizoma Cimicifugae Cimicifuga dahurica (Turcz.) Maxim. of Xingan or Rhizoma Cimicifugae Cimicifuga foetida L..Main product in Shaanxi, Sichuan, Qinghai.
The Rhizoma Atractylodis Macrocephalae, the Radix Paeoniae Alba are monarch in the prescription of the present invention.Contrary gas is held back in the Radix Paeoniae Alba eliminating pathogen in the liver of nourishing blood, acid, slow in pain relieving.The bitter dampness of the Rhizoma Atractylodis Macrocephalae, sweet spleen reinforcing is in the gentleness.Modern study shows that the Rhizoma Atractylodis Macrocephalae has to have to the activity of small intestinal to be strengthened and adjusts two-way function, and nutrition is divided into to body absorption and disease resistance enhancemen all play an important role.
The hot energy of Pericarpium Citri Reticulatae promoting the circulation of QI can dampness be amusing, and the capable then pain of gas is ended.Rhizoma Cimicifugae is gone into the taste warp, is apt to draw the gas rising of sun clearly, and is the key medicine of ascending up spleen-Qi and Yang.Rhizoma Cimicifugae yang invigorating stopping leak and Pericarpium Citri Reticulatae share and are monarch drug, help the merit of the Rhizoma Atractylodis Macrocephalae, Radix Paeoniae Alba invigorating the spleen to arrest diarrhea.
The hot liver that can loose of Radix Saposhnikoviae, the fragrant spleen that can relax, wind energy wins wet, is reason spleen tying-in key medicine.And the pain relieving of tool wind-damp dispelling, walk to scurry the effect of tying-in, Li Gao cloud: " Radix Saposhnikoviae is controlled all over the body pain to the greatest extent, with draw and arrive, the profit agent is also in the wind medicine.If tonifying the spleen and stomach, non-this is quoted unable to walk." so use the Radix Saposhnikoviae adjuvant.
Though this side has only the five tastes, compatibility is reasonable, and flavour of a drug are proper, can spleen reinforcing soil and eliminating pathogen in the liver wood, and the regulating QI machine rushes down with pain relieving.All medicines gather soothing liver and strengthening spleen altogether, the merit of relieving spasm to stop pain.
Beneficial effect of the present invention is:
1, selecting Chinese crude drug for use is raw material, and each component meets the pharmaceutical control and administration rules, utilizes the comprehensive function of the Chinese medicine of respectively distinguishing the flavor of to treat and has loose bowels, and gives full play to the little advantage of herbal toxic effect, nontoxic, can take for a long time.
2, the present invention need not to decoct no bitterness sense, taking convenience.
3, the present invention is cheap.
Clinical observation shows with this medicine composite for curing treats belong to stagnation of liver-QI with deficiency of the spleen person's 68 examples, the total effective rate 92.65% of having loose bowels.Do blood, urine, just routine and hepatic and renal function inspection before and after the treatment, no abnormality seen changes, and does not find in the medication process that this medicine has tangible untoward reaction.Test shows that Drug therapy treatment liver-depression spleen-deficiency and diarrhea is evident in efficacy, has no side effect.
Specific embodiment one
Rhizoma Atractylodis Macrocephalae 800g Radix Paeoniae Alba 500g Pericarpium Citri Reticulatae 400g Radix Saposhnikoviae 500g Rhizoma Cimicifugae 150g
The Rhizoma Atractylodis Macrocephalae, Pericarpium Citri Reticulatae, Radix Saposhnikoviae, the Radix Paeoniae Alba are extracted volatile oil, and medicinal residues and Rhizoma Cimicifugae merge a times decocting and boil twice, concentrate, and spraying, drying, volatile oil sprays into, encapsulated getting final product.Every capsules 0.5g.
Specific embodiment two
Rhizoma Atractylodis Macrocephalae 1000g Radix Paeoniae Alba 700g Pericarpium Citri Reticulatae 500g Radix Saposhnikoviae 700g Rhizoma Cimicifugae 200g
The Rhizoma Atractylodis Macrocephalae, Pericarpium Citri Reticulatae, Radix Saposhnikoviae, the Radix Paeoniae Alba are extracted volatile oil, and medicinal residues and Rhizoma Cimicifugae merge a times decocting and boil twice, concentrate, and spraying, drying, volatile oil sprays into, encapsulated getting final product.Every capsules 0.5g.
Specific embodiment three
Rhizoma Atractylodis Macrocephalae 900g Radix Paeoniae Alba 600g Pericarpium Citri Reticulatae 450g Radix Saposhnikoviae 600g Rhizoma Cimicifugae 180g
The Rhizoma Atractylodis Macrocephalae, Pericarpium Citri Reticulatae, Radix Saposhnikoviae, the Radix Paeoniae Alba are extracted volatile oil, and medicinal residues and Rhizoma Cimicifugae merge a times decocting and boil twice, concentrate, and spraying, drying, volatile oil sprays into, encapsulated getting final product.Every capsules 0.5g.
Claims (5)
1, a kind of pharmaceutical composition for the treatment of liver-depression spleen-deficiency and diarrhea is characterized in that raw material contains following medicaments in part by weight: 45~135 parts of the Rhizoma Atractylodis Macrocephalaes, 30~90 parts of the Radix Paeoniae Albas, 20~60 parts of Pericarpium Citri Reticulataes, 30~90 parts of Radix Saposhnikoviaes, 9~27 parts of Rhizoma Cimicifugaes.
2, require described pharmaceutical composition according to right 1, it is characterized in that raw material contains following medicaments in part by weight: 80~100 parts of the Rhizoma Atractylodis Macrocephalaes, 50~70 parts of the Radix Paeoniae Albas, 40~50 parts of Pericarpium Citri Reticulataes, 50~70 parts of Radix Saposhnikoviaes, 15~20 parts of Rhizoma Cimicifugaes.
3, require the pharmaceutical composition of described treatment liver-depression spleen-deficiency and diarrhea according to right 1,2, it is characterized in that the optimised quantity of each raw material is: 90 parts of the Rhizoma Atractylodis Macrocephalaes, 60 parts of the Radix Paeoniae Albas, 45 parts of Pericarpium Citri Reticulataes, 60 parts of Radix Saposhnikoviaes, 18 parts of Rhizoma Cimicifugaes.
4,, it is characterized in that raw material contains Rhizoma Cimicifugae according to the requirement of right 1,2,3.
5, require described medicine according to right 3, the Rhizoma Atractylodis Macrocephalae, Pericarpium Citri Reticulatae, Radix Saposhnikoviae, the Radix Paeoniae Alba are extracted volatile oil, medicinal residues and Rhizoma Cimicifugae merge a times decocting and boil twice, concentrate, and spraying, drying, volatile oil sprays into, encapsulated getting final product.Every capsules 0.5g.
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CNA2008101021141A CN101239114A (en) | 2008-03-18 | 2008-03-18 | Medicinal composition for treating liver-depression spleen-deficiency and diarrhea and preparation thereof |
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Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN104958508A (en) * | 2015-07-31 | 2015-10-07 | 苏州法莫生物技术有限公司 | Traditional Chinese medicine preparation containing largetrifoliolious bugbane rhizome |
CN105435250A (en) * | 2015-12-23 | 2016-03-30 | 江瑞平 | Contrast medium applicable to liver depression and spleen vacuity type irritable bowel syndrome |
CN105536001A (en) * | 2015-12-23 | 2016-05-04 | 江瑞平 | Contrast agent suitable for liver stagnation and spleen insufficiency type irritable bowel syndrome |
-
2008
- 2008-03-18 CN CNA2008101021141A patent/CN101239114A/en active Pending
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN104958508A (en) * | 2015-07-31 | 2015-10-07 | 苏州法莫生物技术有限公司 | Traditional Chinese medicine preparation containing largetrifoliolious bugbane rhizome |
CN105435250A (en) * | 2015-12-23 | 2016-03-30 | 江瑞平 | Contrast medium applicable to liver depression and spleen vacuity type irritable bowel syndrome |
CN105536001A (en) * | 2015-12-23 | 2016-05-04 | 江瑞平 | Contrast agent suitable for liver stagnation and spleen insufficiency type irritable bowel syndrome |
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Open date: 20080813 |