CN101199873A - 药物洗脱器械用纳米级孔洞药物释放结构及其制备方法 - Google Patents
药物洗脱器械用纳米级孔洞药物释放结构及其制备方法 Download PDFInfo
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- CN101199873A CN101199873A CNA2006101681250A CN200610168125A CN101199873A CN 101199873 A CN101199873 A CN 101199873A CN A2006101681250 A CNA2006101681250 A CN A2006101681250A CN 200610168125 A CN200610168125 A CN 200610168125A CN 101199873 A CN101199873 A CN 101199873A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L31/146—Porous materials, e.g. foams or sponges
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L31/16—Biologically active materials, e.g. therapeutic substances
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
- A61L2300/602—Type of release, e.g. controlled, sustained, slow
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2400/00—Materials characterised by their function or physical properties
- A61L2400/12—Nanosized materials, e.g. nanofibres, nanoparticles, nanowires, nanotubes; Nanostructured surfaces
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Surgery (AREA)
- Vascular Medicine (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Engineering & Computer Science (AREA)
- Dispersion Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Materials For Medical Uses (AREA)
- Media Introduction/Drainage Providing Device (AREA)
- Medicinal Preparation (AREA)
Abstract
Description
支架种类 | H-S(12枚) | Pt(12枚) | N-S(12枚) |
平均管腔丢失(mm) | 1.35 | 0.8 | 0.6 |
平均狭窄程度(%) | 45 | 30 | 25 |
狭窄率(%) | 45.46 | 16.67 | 8.33 |
Claims (17)
Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN2006101681250A CN101199873B (zh) | 2006-12-14 | 2006-12-14 | 药物洗脱器械用纳米级孔洞药物释放结构及其制备方法 |
US12/224,588 US20090112310A1 (en) | 2006-12-14 | 2007-04-05 | Nanoporous Drug Release Structure for Drug Elute Instruments and the Preparation Method Thereof |
PCT/CN2007/001109 WO2008071047A1 (fr) | 2006-12-14 | 2007-04-05 | Structure de libération de medicament nanoporeuse pour instruments d'élution de médicaments et son procédé de préparation |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN2006101681250A CN101199873B (zh) | 2006-12-14 | 2006-12-14 | 药物洗脱器械用纳米级孔洞药物释放结构及其制备方法 |
Publications (2)
Publication Number | Publication Date |
---|---|
CN101199873A true CN101199873A (zh) | 2008-06-18 |
CN101199873B CN101199873B (zh) | 2013-06-19 |
Family
ID=39511240
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN2006101681250A Active CN101199873B (zh) | 2006-12-14 | 2006-12-14 | 药物洗脱器械用纳米级孔洞药物释放结构及其制备方法 |
Country Status (3)
Country | Link |
---|---|
US (1) | US20090112310A1 (zh) |
CN (1) | CN101199873B (zh) |
WO (1) | WO2008071047A1 (zh) |
Cited By (11)
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---|---|---|---|---|
WO2010081393A1 (zh) * | 2009-01-19 | 2010-07-22 | 北京天地和协科技有限公司 | 一种储存和释放多种药物的微孔结构药物洗脱器械及其制备方法 |
CN102240416A (zh) * | 2011-04-25 | 2011-11-16 | 南京大学 | 一种肝素化方法及应用 |
CN102309368A (zh) * | 2010-07-09 | 2012-01-11 | 微创医疗器械(上海)有限公司 | 一种人体管腔载药支架及其制备方法 |
CN102309369A (zh) * | 2010-07-09 | 2012-01-11 | 微创医疗器械(上海)有限公司 | 一种金属支架及其制备方法 |
WO2012003803A1 (zh) * | 2010-07-09 | 2012-01-12 | 微创医疗器械(上海)有限公司 | 一种载药金属支架及其制备方法 |
CN102425000A (zh) * | 2011-11-29 | 2012-04-25 | 哈尔滨工业大学 | NiTi合金表面生物活性氧化钛膜层的制备方法 |
CN101502696B (zh) * | 2009-02-17 | 2012-07-11 | 乐普(北京)医疗器械股份有限公司 | 一种携载基因和/或药物的医疗器械及其制备方法 |
CN105031748A (zh) * | 2015-08-03 | 2015-11-11 | 丹阳纳瑞康纳米科技有限公司 | 一种可控缓释的阿司匹林金属复合材料制备 |
CN108404228A (zh) * | 2018-03-14 | 2018-08-17 | 广东工业大学 | 一种不锈钢纳米载药支架及缓释药剂的制备方法 |
WO2020108539A1 (zh) * | 2018-11-30 | 2020-06-04 | 上海微创医疗器械(集团)有限公司 | 一种医用管材及其制备方法 |
CN113198047A (zh) * | 2021-05-14 | 2021-08-03 | 西安市红会医院 | 一种骨科运动创伤软骨再生支架材料的制备方法 |
Families Citing this family (35)
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US7713297B2 (en) | 1998-04-11 | 2010-05-11 | Boston Scientific Scimed, Inc. | Drug-releasing stent with ceramic-containing layer |
US7018401B1 (en) | 1999-02-01 | 2006-03-28 | Board Of Regents, The University Of Texas System | Woven intravascular devices and methods for making the same and apparatus for delivery of the same |
US20070224235A1 (en) | 2006-03-24 | 2007-09-27 | Barron Tenney | Medical devices having nanoporous coatings for controlled therapeutic agent delivery |
US8187620B2 (en) | 2006-03-27 | 2012-05-29 | Boston Scientific Scimed, Inc. | Medical devices comprising a porous metal oxide or metal material and a polymer coating for delivering therapeutic agents |
US8815275B2 (en) | 2006-06-28 | 2014-08-26 | Boston Scientific Scimed, Inc. | Coatings for medical devices comprising a therapeutic agent and a metallic material |
JP2009542359A (ja) | 2006-06-29 | 2009-12-03 | ボストン サイエンティフィック リミテッド | 選択的被覆部を備えた医療装置 |
EP2068757B1 (en) | 2006-09-14 | 2011-05-11 | Boston Scientific Limited | Medical devices with drug-eluting coating |
CN102525700B (zh) | 2006-10-22 | 2015-05-13 | Idev科技公司 | 支架推进装置 |
US7981150B2 (en) | 2006-11-09 | 2011-07-19 | Boston Scientific Scimed, Inc. | Endoprosthesis with coatings |
US8431149B2 (en) | 2007-03-01 | 2013-04-30 | Boston Scientific Scimed, Inc. | Coated medical devices for abluminal drug delivery |
US8070797B2 (en) | 2007-03-01 | 2011-12-06 | Boston Scientific Scimed, Inc. | Medical device with a porous surface for delivery of a therapeutic agent |
US8067054B2 (en) | 2007-04-05 | 2011-11-29 | Boston Scientific Scimed, Inc. | Stents with ceramic drug reservoir layer and methods of making and using the same |
US7976915B2 (en) | 2007-05-23 | 2011-07-12 | Boston Scientific Scimed, Inc. | Endoprosthesis with select ceramic morphology |
US8002823B2 (en) | 2007-07-11 | 2011-08-23 | Boston Scientific Scimed, Inc. | Endoprosthesis coating |
US7942926B2 (en) * | 2007-07-11 | 2011-05-17 | Boston Scientific Scimed, Inc. | Endoprosthesis coating |
US8815273B2 (en) | 2007-07-27 | 2014-08-26 | Boston Scientific Scimed, Inc. | Drug eluting medical devices having porous layers |
US7931683B2 (en) * | 2007-07-27 | 2011-04-26 | Boston Scientific Scimed, Inc. | Articles having ceramic coated surfaces |
WO2009018340A2 (en) | 2007-07-31 | 2009-02-05 | Boston Scientific Scimed, Inc. | Medical device coating by laser cladding |
JP2010535541A (ja) | 2007-08-03 | 2010-11-25 | ボストン サイエンティフィック リミテッド | 広い表面積を有する医療器具用のコーティング |
US7938855B2 (en) * | 2007-11-02 | 2011-05-10 | Boston Scientific Scimed, Inc. | Deformable underlayer for stent |
US8216632B2 (en) | 2007-11-02 | 2012-07-10 | Boston Scientific Scimed, Inc. | Endoprosthesis coating |
US20090118818A1 (en) * | 2007-11-02 | 2009-05-07 | Boston Scientific Scimed, Inc. | Endoprosthesis with coating |
US8029554B2 (en) | 2007-11-02 | 2011-10-04 | Boston Scientific Scimed, Inc. | Stent with embedded material |
WO2009131911A2 (en) | 2008-04-22 | 2009-10-29 | Boston Scientific Scimed, Inc. | Medical devices having a coating of inorganic material |
WO2009132176A2 (en) | 2008-04-24 | 2009-10-29 | Boston Scientific Scimed, Inc. | Medical devices having inorganic particle layers |
EP2303350A2 (en) | 2008-06-18 | 2011-04-06 | Boston Scientific Scimed, Inc. | Endoprosthesis coating |
US8114153B2 (en) * | 2008-09-05 | 2012-02-14 | Boston Scientific Scimed, Inc. | Endoprostheses |
EP2352460B1 (en) | 2008-11-06 | 2019-01-02 | Biosensors International Group, Ltd. | Surface textured implants |
US8231980B2 (en) | 2008-12-03 | 2012-07-31 | Boston Scientific Scimed, Inc. | Medical implants including iridium oxide |
US8071156B2 (en) | 2009-03-04 | 2011-12-06 | Boston Scientific Scimed, Inc. | Endoprostheses |
US8287937B2 (en) | 2009-04-24 | 2012-10-16 | Boston Scientific Scimed, Inc. | Endoprosthese |
CN102499798A (zh) * | 2011-09-29 | 2012-06-20 | 微创医疗器械(上海)有限公司 | 一种介入医疗器械及其制备方法 |
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ES2930317T3 (es) | 2017-10-11 | 2022-12-09 | Link Waldemar Gmbh Co | Dispositivo implantable de elución de fármacos que comprende una estructura microporosa |
CN110639056B (zh) * | 2019-09-17 | 2021-12-17 | 天津理工大学 | 一种医用镁合金表面释药功能涂层的制备方法 |
Family Cites Families (13)
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JP2683750B2 (ja) * | 1988-06-06 | 1997-12-03 | 住友電気工業株式会社 | カテーテル用バルーン |
US6805898B1 (en) * | 2000-09-28 | 2004-10-19 | Advanced Cardiovascular Systems, Inc. | Surface features of an implantable medical device |
CN1303947C (zh) * | 2001-12-13 | 2007-03-14 | 华东理工大学 | 药物洗脱性心血管支架及其制备方法 |
US7166133B2 (en) * | 2002-06-13 | 2007-01-23 | Kensey Nash Corporation | Devices and methods for treating defects in the tissue of a living being |
US20050070989A1 (en) * | 2002-11-13 | 2005-03-31 | Whye-Kei Lye | Medical devices having porous layers and methods for making the same |
US20050251245A1 (en) * | 2004-05-05 | 2005-11-10 | Karl Sieradzki | Methods and apparatus with porous materials |
US7901451B2 (en) * | 2004-09-24 | 2011-03-08 | Biosensors International Group, Ltd. | Drug-delivery endovascular stent and method for treating restenosis |
EP1879522A2 (en) * | 2005-04-28 | 2008-01-23 | The Regents of The University of California | Compositions comprising nanostructures for cell, tissue and artificial organ growth, and methods for making and using same |
US20070036844A1 (en) * | 2005-08-01 | 2007-02-15 | Ma Peter X | Porous materials having multi-size geometries |
CN100385039C (zh) * | 2005-10-24 | 2008-04-30 | 深圳清华大学研究院 | 一种医用金属表面生物活性纳米复合层制备方法 |
CN100438835C (zh) * | 2005-12-26 | 2008-12-03 | 浙江大学 | 在纯钛牙种植体表面制备具有生物活性多孔结构的方法 |
CN100400113C (zh) * | 2006-08-14 | 2008-07-09 | 董何彦 | 金属支架表面微盲孔载药层的制作方法 |
EP2959925B1 (en) * | 2006-09-15 | 2018-08-29 | Boston Scientific Limited | Medical devices and methods of making the same |
-
2006
- 2006-12-14 CN CN2006101681250A patent/CN101199873B/zh active Active
-
2007
- 2007-04-05 US US12/224,588 patent/US20090112310A1/en not_active Abandoned
- 2007-04-05 WO PCT/CN2007/001109 patent/WO2008071047A1/zh active Application Filing
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WO2010081393A1 (zh) * | 2009-01-19 | 2010-07-22 | 北京天地和协科技有限公司 | 一种储存和释放多种药物的微孔结构药物洗脱器械及其制备方法 |
CN101502696B (zh) * | 2009-02-17 | 2012-07-11 | 乐普(北京)医疗器械股份有限公司 | 一种携载基因和/或药物的医疗器械及其制备方法 |
CN102309369A (zh) * | 2010-07-09 | 2012-01-11 | 微创医疗器械(上海)有限公司 | 一种金属支架及其制备方法 |
WO2012003803A1 (zh) * | 2010-07-09 | 2012-01-12 | 微创医疗器械(上海)有限公司 | 一种载药金属支架及其制备方法 |
CN102309368A (zh) * | 2010-07-09 | 2012-01-11 | 微创医疗器械(上海)有限公司 | 一种人体管腔载药支架及其制备方法 |
CN102309368B (zh) * | 2010-07-09 | 2014-11-05 | 上海微创医疗器械(集团)有限公司 | 一种人体管腔载药支架及其制备方法 |
CN102309369B (zh) * | 2010-07-09 | 2014-11-05 | 上海微创医疗器械(集团)有限公司 | 一种金属支架及其制备方法 |
CN102240416A (zh) * | 2011-04-25 | 2011-11-16 | 南京大学 | 一种肝素化方法及应用 |
CN102425000A (zh) * | 2011-11-29 | 2012-04-25 | 哈尔滨工业大学 | NiTi合金表面生物活性氧化钛膜层的制备方法 |
CN105031748A (zh) * | 2015-08-03 | 2015-11-11 | 丹阳纳瑞康纳米科技有限公司 | 一种可控缓释的阿司匹林金属复合材料制备 |
CN108404228A (zh) * | 2018-03-14 | 2018-08-17 | 广东工业大学 | 一种不锈钢纳米载药支架及缓释药剂的制备方法 |
WO2020108539A1 (zh) * | 2018-11-30 | 2020-06-04 | 上海微创医疗器械(集团)有限公司 | 一种医用管材及其制备方法 |
CN111249601A (zh) * | 2018-11-30 | 2020-06-09 | 上海微创医疗器械(集团)有限公司 | 一种多孔球囊及其制备方法 |
CN113198047A (zh) * | 2021-05-14 | 2021-08-03 | 西安市红会医院 | 一种骨科运动创伤软骨再生支架材料的制备方法 |
Also Published As
Publication number | Publication date |
---|---|
US20090112310A1 (en) | 2009-04-30 |
WO2008071047A1 (fr) | 2008-06-19 |
CN101199873B (zh) | 2013-06-19 |
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Effective date of registration: 20161019 Address after: 518054 Guangdong city of Shenzhen province Nanshan District Guangdong streets Changhong Technology Park Building Room 503 Patentee after: (Shenzhen) International Development Centre Limited Address before: 102200 Beijing City, Changping District Road No. 10 white floating Beikong 3 storey building Patentee before: Lepu (Beijing) Medical Equipment Co.,Ltd. |
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Effective date of registration: 20170420 Address after: 102200 Beijing, Changping District super Road, building No. 37, No. 7 Patentee after: Lepu (Beijing) Medical Equipment Co.,Ltd. Address before: 518054 Guangdong city of Shenzhen province Nanshan District Guangdong streets Changhong Technology Park Building Room 503 Patentee before: (Shenzhen) International Development Centre Limited |