CN101195559A - 白藜芦醇纳米结晶的制备方法及其应用 - Google Patents
白藜芦醇纳米结晶的制备方法及其应用 Download PDFInfo
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- CN101195559A CN101195559A CNA2007101885939A CN200710188593A CN101195559A CN 101195559 A CN101195559 A CN 101195559A CN A2007101885939 A CNA2007101885939 A CN A2007101885939A CN 200710188593 A CN200710188593 A CN 200710188593A CN 101195559 A CN101195559 A CN 101195559A
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- Prior art keywords
- resveratrol
- trans
- nanocrystal
- acid
- alcohol
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 238000000034 method Methods 0.000 title claims abstract description 11
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- 230000008569 process Effects 0.000 title claims description 8
- QNVSXXGDAPORNA-UHFFFAOYSA-N Resveratrol Natural products OC1=CC=CC(C=CC=2C=C(O)C(O)=CC=2)=C1 QNVSXXGDAPORNA-UHFFFAOYSA-N 0.000 title description 5
- 235000021283 resveratrol Nutrition 0.000 title description 5
- 229940016667 resveratrol Drugs 0.000 title description 5
- 238000007709 nanocrystallization Methods 0.000 title 1
- 230000000694 effects Effects 0.000 claims abstract description 21
- 239000002537 cosmetic Substances 0.000 claims abstract description 13
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims abstract description 9
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- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 20
- 239000000243 solution Substances 0.000 claims description 15
- 235000021355 Stearic acid Nutrition 0.000 claims description 12
- QIQXTHQIDYTFRH-UHFFFAOYSA-N octadecanoic acid Chemical compound CCCCCCCCCCCCCCCCCC(O)=O QIQXTHQIDYTFRH-UHFFFAOYSA-N 0.000 claims description 12
- OQCDKBAXFALNLD-UHFFFAOYSA-N octadecanoic acid Natural products CCCCCCCC(C)CCCCCCCCC(O)=O OQCDKBAXFALNLD-UHFFFAOYSA-N 0.000 claims description 12
- 239000008117 stearic acid Substances 0.000 claims description 12
- 238000002425 crystallisation Methods 0.000 claims description 11
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- 206010002198 Anaphylactic reaction Diseases 0.000 claims description 4
- 208000003455 anaphylaxis Diseases 0.000 claims description 4
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- POULHZVOKOAJMA-UHFFFAOYSA-N dodecanoic acid Chemical compound CCCCCCCCCCCC(O)=O POULHZVOKOAJMA-UHFFFAOYSA-N 0.000 claims description 4
- WRIDQFICGBMAFQ-UHFFFAOYSA-N (E)-8-Octadecenoic acid Natural products CCCCCCCCCC=CCCCCCCC(O)=O WRIDQFICGBMAFQ-UHFFFAOYSA-N 0.000 claims description 2
- LQJBNNIYVWPHFW-UHFFFAOYSA-N 20:1omega9c fatty acid Natural products CCCCCCCCCCC=CCCCCCCCC(O)=O LQJBNNIYVWPHFW-UHFFFAOYSA-N 0.000 claims description 2
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- OYHQOLUKZRVURQ-HZJYTTRNSA-N Linoleic acid Chemical compound CCCCC\C=C/C\C=C/CCCCCCCC(O)=O OYHQOLUKZRVURQ-HZJYTTRNSA-N 0.000 claims description 2
- 239000005642 Oleic acid Substances 0.000 claims description 2
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- XLOMVQKBTHCTTD-UHFFFAOYSA-N Zinc monoxide Chemical compound [Zn]=O XLOMVQKBTHCTTD-UHFFFAOYSA-N 0.000 description 4
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- 208000010110 spontaneous platelet aggregation Diseases 0.000 description 1
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- 230000024883 vasodilation Effects 0.000 description 1
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Abstract
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Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
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CN2007101885939A CN101195559B (zh) | 2007-12-12 | 2007-12-12 | 白藜芦醇纳米结晶的制备方法及其应用 |
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CN2007101885939A CN101195559B (zh) | 2007-12-12 | 2007-12-12 | 白藜芦醇纳米结晶的制备方法及其应用 |
Publications (2)
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CN101195559A true CN101195559A (zh) | 2008-06-11 |
CN101195559B CN101195559B (zh) | 2011-04-06 |
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Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102125537A (zh) * | 2010-12-07 | 2011-07-20 | 沈阳药科大学 | 白藜芦醇及其衍生物的医药新用途 |
CN108514539A (zh) * | 2018-07-11 | 2018-09-11 | 广州市雅薏诗化妆品有限公司 | 一种基于温和效果化妆品用防腐组合物及该化妆品制备方法 |
CN113509421A (zh) * | 2021-08-19 | 2021-10-19 | 河南科技大学 | 一种牡丹籽壳化妆品防晒原料及其应用 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1621401A (zh) * | 2003-11-28 | 2005-06-01 | 张�浩 | 一种从虎杖中提取高***藜芦醇的方法 |
CN1321961C (zh) * | 2005-11-11 | 2007-06-20 | 余淑娴 | 一种从虎杖中提取纯化白藜芦醇的新方法 |
CN1896255A (zh) * | 2006-06-17 | 2007-01-17 | 曹庸 | 微生物转化虎杖材料提取高纯白藜芦醇的工艺 |
-
2007
- 2007-12-12 CN CN2007101885939A patent/CN101195559B/zh active Active
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102125537A (zh) * | 2010-12-07 | 2011-07-20 | 沈阳药科大学 | 白藜芦醇及其衍生物的医药新用途 |
CN108514539A (zh) * | 2018-07-11 | 2018-09-11 | 广州市雅薏诗化妆品有限公司 | 一种基于温和效果化妆品用防腐组合物及该化妆品制备方法 |
CN108514539B (zh) * | 2018-07-11 | 2021-07-27 | 广州市腾宇化妆品有限公司 | 一种基于温和效果化妆品用防腐组合物及该化妆品制备方法 |
CN113509421A (zh) * | 2021-08-19 | 2021-10-19 | 河南科技大学 | 一种牡丹籽壳化妆品防晒原料及其应用 |
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Publication number | Publication date |
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CN101195559B (zh) | 2011-04-06 |
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C06 | Publication | ||
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EE01 | Entry into force of recordation of patent licensing contract |
Assignee: Xi'an Tianxing Jian natural biological products Co., Ltd. Assignor: Wang Yun Contract record no.: 2012610000100 Denomination of invention: Process for producing resveratrol nano-crystallization and uses thereof Granted publication date: 20110406 License type: Exclusive License Open date: 20080611 Record date: 20120608 |
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TR01 | Transfer of patent right |
Effective date of registration: 20171123 Address after: 710075 1 unit 1, unit 1030, room 5, Rong Xin Road, Xi'an high tech Zone, Shaanxi Patentee after: Xi'an Tianxing Jian natural biological products Co., Ltd. Address before: No. 5, Hsin Xin Road, Xi'an high tech Zone, Shaanxi Province Patentee before: Wang Yun |
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PE01 | Entry into force of the registration of the contract for pledge of patent right | ||
PE01 | Entry into force of the registration of the contract for pledge of patent right |
Denomination of invention: Process for producing resveratrol nano-crystallization and uses thereof Effective date of registration: 20180211 Granted publication date: 20110406 Pledgee: Xi'an innovation financing Company limited by guarantee Pledgor: Xi'an Tianxing Jian natural biological products Co., Ltd. Registration number: 2018990000141 |
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PC01 | Cancellation of the registration of the contract for pledge of patent right |
Date of cancellation: 20181207 Granted publication date: 20110406 Pledgee: Xi'an innovation financing Company limited by guarantee Pledgor: Xi'an Tianxing Jian natural biological products Co., Ltd. Registration number: 2018990000141 |
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PE01 | Entry into force of the registration of the contract for pledge of patent right | ||
PE01 | Entry into force of the registration of the contract for pledge of patent right |
Denomination of invention: Process for producing resveratrol nano-crystallization and uses thereof Effective date of registration: 20191227 Granted publication date: 20110406 Pledgee: Xi'an innovation financing Company limited by guarantee Pledgor: Xi'an Tianxing Jian natural biological products Co., Ltd. Registration number: Y2019990000811 |
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PC01 | Cancellation of the registration of the contract for pledge of patent right |
Date of cancellation: 20201208 Granted publication date: 20110406 Pledgee: Xi'an innovation financing Company limited by guarantee Pledgor: Xi'an Tianxing Jian natural biological products Co.,Ltd. Registration number: Y2019990000811 |
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PC01 | Cancellation of the registration of the contract for pledge of patent right |