CN101167872B - Medicinal composition for beautifying and face-nourishing and preparation method thereof - Google Patents
Medicinal composition for beautifying and face-nourishing and preparation method thereof Download PDFInfo
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- CN101167872B CN101167872B CN2007101769020A CN200710176902A CN101167872B CN 101167872 B CN101167872 B CN 101167872B CN 2007101769020 A CN2007101769020 A CN 2007101769020A CN 200710176902 A CN200710176902 A CN 200710176902A CN 101167872 B CN101167872 B CN 101167872B
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Abstract
The invention discloses a medicament combination for keeping looks, and process for preparation. The invention comprises astragalus, cistanche, angelica sinensis, polygonum capitatum, donkey-hide gelatin, rehmanniae vaporata, Ligusticum chuanxiong, kudzu root, radix salvia miltiorrhiza, mature rhubarb horsetails, cimicifuga foetida, and cinnamomum cassia. Drug components of the invention has the efficacies of enriching blood and promoting blood flow, promoting spleen Yang and benefiting vital energy, and relaxing bowel and expelling toxin, which is used for keeping looks, removing speckles and curing illness, and delaying skin senility and the like. The invention can effectively decrease blood lipid, decrease blood viscosity, adjust blood circulation, prompt metabolism, and delay the appearance of wrinkles. The invention has the advantages of simple formula, convenient production, easy taking, and distinct effect, and which has extensive application valve.
Description
Technical field the present invention relates to a kind of pharmaceutical composition and preparation method thereof, and belonging to enriches blood invigorates blood circulation, the technical field of pharmaceuticals of yang invigorating QI invigorating and catharsis and toxin expelling.Be used for looks improving and the skin nourishing, speckle dispelling is cured the disease and delaying skin aging etc.
The background technology traditional Chinese medical science has very strong advantage aspect promoting blood circulation to remove obstruction in the collateral, benefiting vital QI and blood and the transfer healthy energy, has to promote QI-blood circulation, cleaning blood vessel, and blood fat reducing and blood viscosity are regulated blood circulation, enhances metabolism and the effect of catharsis and toxin expelling.
The traditional Chinese medical science thinks that fur is led by lung, and lung and spleen kidney are in close relations, the spleen being the foundation of acquired constitution, source of generating QI and blood, The spleen has the function to transport and transform nutrients, main muscle, though the lung is concerned with QI of the whole body, kidney is congenital, but all need the nourishing of the angry blood of spleenization, and kidney is also led the sun of the whole body, suffer from a deficiency of the kidney and to lead also void of lung spleen.So have only lung spleen renal function normal, just can QI and blood fill Sheng, the extremity bones of the body collectively is healthy, and skin is ruddy.
The purpose of this invention is to provide a kind of looks improving and the skin nourishing, speckle dispelling is cured the disease and the Chinese medicine preparation of delaying skin aging.The sweet temperature of the Radix Astragali is gone into the spleen lung meridian in the side, not only is longer than invigorating middle warmer gas lift spleen sun, can also tonifying the lung gas, and the Radix Astragali includes polysaccharide and several amino acids, protein, folic acid, Citrin and trace element-selenium and ferrum calcium phosphorus magnesium etc.; The sweet Wen Zhirun of Radix Angelicae Sinensis returns spleen channel, is the key medicine of enriching blood, and not only can enrich blood, and can also invigorate blood circulation, intestine moistening, and two medicines share and strengthen the benefiting vital QI and blood effect, and blood being the mother of qi, qi as the commander of blood, and the capable then blood of gas is capable, also reaches the purpose of invigorating blood circulation.Big yellow maturity is with the property that has reduced its bitter cold, and it is stagnant to cleanse in the intestinal stasis of blood, blood circulation promoting and blood stasis dispelling, reaching the effect of catharsis and toxin expelling, with Radix Angelicae Sinensis, the Radix Astragali be monarch drug altogether.The taste warp is gone in the hot sweet cold of Rhizoma Cimicifugae, Radix Puerariae, all can the elevate a turnable ladder yang-energy, strengthened the yang invigorating qi invigorating functions, and with Radix Et Rhizoma Rhei compatibility, one rise and one drop, helping the effect of lung regulating fluid apssage, and it is normal to cause big intestinal function.Herba Cistanches not only can kidney-replenishing, can also loosening bowel to relieve constipation, be all minister with above two flavors.The Radix Polygoni Multiflori, Colla Corii Asini, Radix Rehmanniae Preparata share the YIN nourishing of enriching blood; The Radix Salviae Miltiorrhizae bitter cold, the regulating menstruation of energy promoting blood circulation and cooling blood, the Rhizoma Chuanxiong blood-activating and qi-promoting of joining Xin Wen; Cortex Cinnamomi property acrid-sweet flavor heat, it is supporing yang to mend fire, and current QI and blood all is an adjuvant.All medicine compatibilities have to rise to have and fall, and have to mend to have and rush down, and playing altogether enriches blood invigorates blood circulation, yang invigorating QI invigorating, the effect of catharsis and toxin expelling.
Summary of the invention the object of the present invention is to provide a kind of evident in efficacy, taking convenience, side effect little, and enriching blood of being fit to take for a long time invigorated blood circulation, the Chinese medicinal capsule of yang invigorating QI invigorating and catharsis and toxin expelling.
The present invention also provides the preparation method of this Chinese medicinal capsule.
Pharmaceutical composition of the present invention can be used for that looks improving and the skin nourishing, speckle dispelling are cured the disease, delaying skin aging, blood fat reducing and blood viscosity, adjusting blood circulation, enhance metabolism and effect such as catharsis and toxin expelling.
Chinese medicinal capsule of the present invention is prepared from by the following weight parts proportion raw material:
10～150 parts of 100～500 parts of the Radixs Astragali, 100～500 parts of Herba Cistanches, 100～400 parts of Radix Angelicae Sinensis, 100～400 parts of the Radixs Polygoni Multiflori, 100～400 parts in Colla Corii Asini, 100～350 parts in Radix Rehmanniae Preparata, 100～350 parts of Rhizoma Chuanxiongs, 100～300 parts of Radix Puerariaes, 100～300 parts of Radix Salviae Miltiorrhizaes, 50～200 parts of Radix Et Rhizoma Rhei, 50～200 parts of Rhizoma Cimicifugaes and Cortex Cinnamomis.
Chinese medicinal capsule of the present invention is prepared from by following preferred weight part proportion raw material:
10～100 parts of 200～400 parts of the Radixs Astragali, 200～300 parts of Herba Cistanches, 150～300 parts of Radix Angelicae Sinensis, 150～300 parts of the Radixs Polygoni Multiflori, 150～250 parts in Colla Corii Asini, 150～250 parts in Radix Rehmanniae Preparata, 100～200 parts of Rhizoma Chuanxiongs, 100～200 parts of Radix Puerariaes, 100～200 parts of Radix Salviae Miltiorrhizaes, 50～100 parts of Radix Et Rhizoma Rhei, 50～100 parts of Rhizoma Cimicifugaes and Cortex Cinnamomis.
Chinese medicinal capsule of the present invention is prepared from by following optimum weight part proportion raw material:
50 parts of 250 parts of the Radixs Astragali, 220 parts of Herba Cistanches, 200 parts of Radix Angelicae Sinensis, the Radix Polygoni Multiflori 200,180 parts in Colla Corii Asini, 180 parts in Radix Rehmanniae Preparata, 160 parts of Rhizoma Chuanxiongs, 150 parts of Radix Puerariaes, 150 parts of Radix Salviae Miltiorrhizaes, 80 parts of Radix Et Rhizoma Rhei, 70 parts of Rhizoma Cimicifugaes and Cortex Cinnamomis.
Chinese medicinal capsule of the present invention can be prepared from by following method:
1, Radix Angelicae Sinensis, Rhizoma Chuanxiong, the Cortex Cinnamomi of described weight portion are extracted volatile oil.
2, the medicinal residues that Radix Angelicae Sinensis, Rhizoma Chuanxiong, Cortex Cinnamomi are extracted behind the volatile oil decoct with water secondary together with Rhizoma Cimicifugae, the Radix Polygoni Multiflori, Radix Rehmanniae Preparata, Herba Cistanches, the Radix Astragali, each 2 hours, filter, adding ethanol after collecting decoction concentrates makes and contains the alcohol amount and reach 60%, place cold preservation 24 hours, draw supernatant, it is standby to concentrate the back.
3, Radix Puerariae is with 85% alcohol reflux three times, and 4 hours for the first time, second and third time each 3 hours filtered, merging filtrate, and it is standby to concentrate the back.
4, Radix Salviae Miltiorrhizae added alcohol reflux 1.5 hours for the first time, filtered, and added 50% alcohol reflux 1.5 hours for the second time, filtered, and it is standby that merging filtrate concentrates the back.
5, Radix Et Rhizoma Rhei is with 70% alcohol reflux three times, and each 1.5 hours, to filter, it is standby that filtrate concentrates the back.
6, merge above medicinal liquid, after Colla Corii Asini is dissolved with boiled water, be blended into medicinal liquid, be concentrated into relative density 1.25 (60 ℃) extractum, spray drying sprays into mixing behind Radix Angelicae Sinensis, Rhizoma Chuanxiong, the cinnamomic volatile oil, takes out after vexed 1～2 day to incapsulate.
Prescription of the present invention is made up of 12 flavor Chinese medicines such as the Radix Astragali, Herba Cistanches, Radix Angelicae Sinensis, the Radix Polygoni Multiflori, Colla Corii Asini, Radix Rehmanniae Preparata, Rhizoma Chuanxiong, Radix Puerariae, Radix Salviae Miltiorrhizae, Radix Et Rhizoma Rhei, Rhizoma Cimicifugae and Cortex Cinnamomi.Modern pharmacological research shows: the Radix Astragali not only has the enhanced effect of panimmunity to body in the side, also has slow down aging and antioxidation.Old rat clothes Radix Astagali decoct can reduce the collagen content of aorta and lung and similar to young rat; To people's tire kidney or the Mongolian stilbene decoct of newborn rat nephrocyte cultivation adding viable count is increased, rats gavaged (+)-Astragenol extract makes the active rising of whole blood SOD, the obvious minimizing of lipid peroxidation (LPO); Radix Et Rhizoma Rhei, Radix Angelicae Sinensis, Radix Puerariae all have effect for reducing fat.Wherein Radix Et Rhizoma Rhei also has discharge function, and main component is an anthraquinone glycoside, and wherein luxuriant activity of rushing down glycosides A is the strongest, aloe-emodin, chrysophanic acid a little less than; Radix Et Rhizoma Rhei water extract or ethanol extract have the effect of cholesterol reducing mass formed by blood stasis.Radix Angelicae Sinensis powder gavages has the blood fat reducing effect to rat and rabbit experiment hyperlipidemia mass formed by blood stasis; In high lipid food, add ferulic acid feed rat, can significantly suppress serum cholesterol level, can also enhancing human body immunity power.The contained osajin formoononetin of Radix Puerariae can reduce serum cholesterol, and genistein can reduce triacylglycerol, and daiazi also has effect for reducing blood fat.Radix Salviae Miltiorrhizae has role and influence to hormonal system.Wherein TANSHINONES also has the antagonism androgenic effect except having estrogenic activity.The mouse gavaging Radix Salviae Miltiorrhizae is to having the rising effect because the content of liver, spleen DNA and the trace element zinc of the yang deficiency animal that hydrocortisone caused, manganese, copper, ferrum reduces; Radix Salviae Miltiorrhizae and Herba Cistanches all have role and influence to hormonal system.Wherein TANSHINONES also has the antagonism androgenic effect except having estrogenic activity.The mouse gavaging Herba Cistanches is to having the rising effect because the content of liver, spleen DNA and the trace element zinc of the yang deficiency animal that hydrocortisone caused, manganese, copper, ferrum reduces; Female rats gavaged Herba Cistanches decoct can strengthen the short luteal function of hypothalamic-pituitary-ovarian.Rhizoma Cimicifugae, Rhizoma Chuanxiong are also influential to immunologic function, can also strengthen digestive function and Cortex Cinnamomi is for oral administration, get rid of the intestinal pneumatosis, and Colla Corii Asini contains several amino acids, and its contained glycine can promote the absorption of calcium.
The present invention is used for that looks improving and the skin nourishing, speckle dispelling are cured the disease, the pharmaceutical composition of delaying skin aging shows through effect experiment, toxicological test and stability experiment, and is evident in efficacy, nontoxic, good stability, patient's taking convenience.
Through clinical experiment, we can be used for that looks improving and the skin nourishing, speckle dispelling are cured the disease, delaying skin aging, and this Chinese medicinal capsule carries out observation of curative effect to 201 routine cases, finds that this capsular total effective rate reaches 95.52%, so is with a wide range of applications.
The specific embodiment
Embodiment 1:
30 parts of 200 parts of the Radixs Astragali, 200 parts of Herba Cistanches, 150 parts of Radix Angelicae Sinensis, the Radix Polygoni Multiflori 150,140 parts in Colla Corii Asini, 140 parts in Radix Rehmanniae Preparata, 120 parts of Rhizoma Chuanxiongs, 100 parts of Radix Puerariaes, 100 parts of Radix Salviae Miltiorrhizaes, 50 parts of Radix Et Rhizoma Rhei, 50 parts of Rhizoma Cimicifugaes and Cortex Cinnamomis.Radix Angelicae Sinensis, Rhizoma Chuanxiong, the Cortex Cinnamomi of described weight portion are extracted volatile oil, medicinal residues decoct with water secondary together with Rhizoma Cimicifugae, the Radix Polygoni Multiflori, Radix Rehmanniae Preparata, Herba Cistanches, the Radix Astragali, each 2 hours, filter, adding ethanol after collecting decoction concentrates makes and contains the alcohol amount and reach 60%, place cold preservation 24 hours, draw supernatant, it is standby to concentrate the back; Radix Puerariae is with 85% alcohol reflux three times, and 4 hours for the first time, second and third time each 3 hours filtered, merging filtrate, and it is standby to concentrate the back; Radix Salviae Miltiorrhizae added alcohol reflux 1.5 hours for the first time, filtered, and added 50% alcohol reflux 1.5 hours for the second time, filtered, and it is standby that merging filtrate concentrates the back.Radix Et Rhizoma Rhei is with 70% alcohol reflux three times, and each 1.5 hours, to filter, it is standby that filtrate concentrates the back.Merge above medicinal liquid, be blended into medicinal liquid after Colla Corii Asini is dissolved with boiled water, be concentrated into relative density 1.25 (60 ℃) extractum, spray drying sprays into mixing behind Radix Angelicae Sinensis, Rhizoma Chuanxiong, the cinnamomic volatile oil, takes out after vexed 1～2 day to incapsulate.Every capsules 0.5g.Instructions of taking: every day 3 times, each 3.
Embodiment 2:
80 parts of 300 parts of the Radixs Astragali, 300 parts of Herba Cistanches, 240 parts of Radix Angelicae Sinensis, the Radix Polygoni Multiflori 240,200 parts in Colla Corii Asini, 200 parts in Radix Rehmanniae Preparata, 180 parts of Rhizoma Chuanxiongs, 180 parts of Radix Puerariaes, 160 parts of Radix Salviae Miltiorrhizaes, 100 parts of Radix Et Rhizoma Rhei, 100 parts of Rhizoma Cimicifugaes and Cortex Cinnamomis.Radix Angelicae Sinensis, Rhizoma Chuanxiong, the Cortex Cinnamomi of described weight portion are extracted volatile oil, medicinal residues decoct with water secondary together with Rhizoma Cimicifugae, the Radix Polygoni Multiflori, Radix Rehmanniae Preparata, Herba Cistanches, the Radix Astragali, each 2 hours, filter, adding ethanol after collecting decoction concentrates makes and contains the alcohol amount and reach 60%, place cold preservation 24 hours, draw supernatant, it is standby to concentrate the back; Radix Puerariae is with 85% alcohol reflux three times, and 4 hours for the first time, second and third time each 3 hours filtered, merging filtrate, and it is standby to concentrate the back; Radix Salviae Miltiorrhizae added alcohol reflux 1.5 hours for the first time, filtered, and added 50% alcohol reflux 1.5 hours for the second time, filtered, and it is standby that merging filtrate concentrates the back.Radix Et Rhizoma Rhei is with 70% alcohol reflux three times, and each 1.5 hours, filter, it is standby that filtrate concentrates the back.Merge above medicinal liquid, be blended into medicinal liquid after Colla Corii Asini is dissolved with boiled water, be concentrated into relative density 1.25 (60 ℃) extractum, spray drying sprays into mixing behind Radix Angelicae Sinensis, Rhizoma Chuanxiong, the cinnamomic volatile oil, takes out after vexed 1～2 day to incapsulate.Every capsules 0.5g.Instructions of taking: every day 3 times, each 3.
Embodiment 3:
50 parts of 250 parts of the Radixs Astragali, 220 parts of Herba Cistanches, 200 parts of Radix Angelicae Sinensis, the Radix Polygoni Multiflori 200,180 parts in Colla Corii Asini, 180 parts in Radix Rehmanniae Preparata, 160 parts of Rhizoma Chuanxiongs, 150 parts of Radix Puerariaes, 150 parts of Radix Salviae Miltiorrhizaes, 80 parts of Radix Et Rhizoma Rhei, 70 parts of Rhizoma Cimicifugaes and Cortex Cinnamomis.Radix Angelicae Sinensis, Rhizoma Chuanxiong, the Cortex Cinnamomi of described weight portion are extracted volatile oil, medicinal residues decoct with water secondary together with Rhizoma Cimicifugae, the Radix Polygoni Multiflori, Radix Rehmanniae Preparata, Herba Cistanches, the Radix Astragali, each 2 hours, filter, adding ethanol after collecting decoction concentrates makes and contains the alcohol amount and reach 60%, place cold preservation 24 hours, draw supernatant, it is standby to concentrate the back; Radix Puerariae is with 85% alcohol reflux three times, and 4 hours for the first time, second and third time each 3 hours filtered, merging filtrate, and it is standby to concentrate the back; Radix Salviae Miltiorrhizae added alcohol reflux 1.5 hours for the first time, filtered, and added 50% alcohol reflux 1.5 hours for the second time, filtered, and it is standby that merging filtrate concentrates the back.Radix Et Rhizoma Rhei is with 70% alcohol reflux three times, and each 1.5 hours, filter, it is standby that filtrate concentrates the back.Merge above medicinal liquid, be blended into medicinal liquid after Colla Corii Asini is dissolved with boiled water, be concentrated into relative density 1.25 (60 ℃) extractum, spray drying sprays into mixing behind Radix Angelicae Sinensis, Rhizoma Chuanxiong, the cinnamomic volatile oil, takes out after vexed 1～2 day to incapsulate.Every capsules 0.5g.Instructions of taking: every day 3 times, each 3.
Claims (4)
1. pharmaceutical composition that is used for looks improving and the skin nourishing is characterized in that this pharmaceutical composition is formed by the feedstock production of following weight parts: 10～150 parts of 100～500 parts of the Radixs Astragali, 100～500 parts of Herba Cistanches, 100～400 parts of Radix Angelicae Sinensis, 100～400 parts of the Radixs Polygoni Multiflori, 100～400 parts in Colla Corii Asini, 100～350 parts in Radix Rehmanniae Preparata, 100～350 parts of Rhizoma Chuanxiongs, 100～300 parts of Radix Puerariaes, 100～300 parts of Radix Salviae Miltiorrhizaes, 50～200 parts of Radix Et Rhizoma Rhei, 50～200 parts of Rhizoma Cimicifugaes and Cortex Cinnamomis.
2. pharmaceutical composition according to claim 1 is characterized in that this pharmaceutical composition is formed by the feedstock production of following weight parts: 10～100 parts of 200～400 parts of the Radixs Astragali, 200～300 parts of Herba Cistanches, 150～300 parts of Radix Angelicae Sinensis, 150～300 parts of the Radixs Polygoni Multiflori, 150～250 parts in Colla Corii Asini, 150～250 parts in Radix Rehmanniae Preparata, 100～200 parts of Rhizoma Chuanxiongs, 100～200 parts of Radix Puerariaes, 100～200 parts of Radix Salviae Miltiorrhizaes, 50～100 parts of Radix Et Rhizoma Rhei, 50～100 parts of Rhizoma Cimicifugaes and Cortex Cinnamomis.
3. according to claim 1 or the 2 described pharmaceutical compositions that are used for looks improving and the skin nourishing, it is characterized in that this pharmaceutical composition is formed by the feedstock production of following weight parts: 50 parts of 250 parts of the Radixs Astragali, 220 parts of Herba Cistanches, 200 parts of Radix Angelicae Sinensis, the Radix Polygoni Multiflori 200,180 parts in Colla Corii Asini, 180 parts in Radix Rehmanniae Preparata, 160 parts of Rhizoma Chuanxiongs, 150 parts of Radix Puerariaes, 150 parts of Radix Salviae Miltiorrhizaes, 80 parts of Radix Et Rhizoma Rhei, 70 parts of Rhizoma Cimicifugaes and Cortex Cinnamomis.
4. pharmaceutical composition according to claim 3, Radix Angelicae Sinensis, Rhizoma Chuanxiong, the Cortex Cinnamomi of described weight portion are extracted volatile oil, medicinal residues decoct with water secondary together with Rhizoma Cimicifugae, the Radix Polygoni Multiflori, Radix Rehmanniae Preparata, Herba Cistanches, the Radix Astragali, each 2 hours, filter, add ethanol after collecting decoction concentrates and make and contain the alcohol amount and reach 60%, place cold preservation 24 hours, draw supernatant, it is standby to concentrate the back; Radix Puerariae is with 85% alcohol reflux three times, and 4 hours for the first time, second and third time each 3 hours filtered, merging filtrate, and it is standby to concentrate the back; Radix Salviae Miltiorrhizae added alcohol reflux 1.5 hours for the first time, filtered, and added 50% alcohol reflux 1.5 hours for the second time, filtered, and it is standby that merging filtrate concentrates the back; Radix Et Rhizoma Rhei is with 70% alcohol reflux three times, and each 1.5 hours, to filter, it is standby that filtrate concentrates the back; Merge above medicinal liquid, after Colla Corii Asini is dissolved with boiled water, be blended into medicinal liquid, be concentrated into 60 ℃ of following relative density 1.25 extractum, spray drying sprays into mixing behind Radix Angelicae Sinensis, Rhizoma Chuanxiong, the cinnamomic volatile oil, takes out after vexed 1～2 day to incapsulate; Every capsules 0.5g.
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| CN2007101769020A CN101167872B (en) | 2007-11-07 | 2007-11-07 | Medicinal composition for beautifying and face-nourishing and preparation method thereof |
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| CN101167872B true CN101167872B (en) | 2010-06-23 |
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| CN103655447B (en) * | 2013-12-20 | 2015-09-02 | 南阳市食用菌技术交流中心（普通合伙） | A kind of compositions of looks improving and the skin nourishing |
| CN104490745A (en) * | 2014-12-10 | 2015-04-08 | 沈华辉 | Face-beautifying cubilose face mask and decocting method thereof |
| CN106213503A (en) * | 2016-08-16 | 2016-12-14 | 唐莎 | A kind of beauty face-whitening-nourishing medicated diet |
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| CN1524429A (en) * | 2003-02-24 | 2004-09-01 | 刘玉峰 | Face-caring body-beautifying egg and its preparing process |
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| CN1524429A (en) * | 2003-02-24 | 2004-09-01 | 刘玉峰 | Face-caring body-beautifying egg and its preparing process |
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