CN101156649A - A chinese medicinal herb dynamiting immunizator for feed additive - Google Patents

A chinese medicinal herb dynamiting immunizator for feed additive Download PDF

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Publication number
CN101156649A
CN101156649A CNA2007101852649A CN200710185264A CN101156649A CN 101156649 A CN101156649 A CN 101156649A CN A2007101852649 A CNA2007101852649 A CN A2007101852649A CN 200710185264 A CN200710185264 A CN 200710185264A CN 101156649 A CN101156649 A CN 101156649A
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China
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herbal medicine
chinese herbal
chinese
feed additive
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CNA2007101852649A
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Chinese (zh)
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CN101156649B (en
Inventor
张峰
左晓磊
马书林
王昆
韩爱云
吴占军
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Institute of Grain and Oil Crops of Hebei Academy of Agriculture and Forestry Sciences
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Institute of Grain and Oil Crops of Hebei Academy of Agriculture and Forestry Sciences
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Publication of CN101156649A publication Critical patent/CN101156649A/en
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    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P60/00Technologies relating to agriculture, livestock or agroalimentary industries
    • Y02P60/80Food processing, e.g. use of renewable energies or variable speed drives in handling, conveying or stacking
    • Y02P60/87Re-use of by-products of food processing for fodder production

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Abstract

The invention relates to a Chinese herbalmedicine weight increment immunizing agent used in a feed additive. The invention adopts the medicament made by components with the following weight ratio that: hawthorn is 25 to 35 parts, magnolia bark is 8 to 12 parts, immature bitter orange is 8 to 10 parts, atractylodes rhizome is 8 to 12 parts, milkvetch root is 15 to 20 parts, maifan stone is 1.5 to 2.0 parts, gynostemma pentaphyllum is 4 to 6 parts, tangerine peel is 0.8 to 1.5 parts, medicated leaven is 0.8 to 1.5 parts, licorice is 0.4 to 0.8 parts, malt is 5 to 15 parts, and chuanxiong rhizome is 0.4 to 0.8 parts. The invention determines the research and development of the Chinese herbal medicine weight increment immunizing agent for livestock breeding according to the traditional Chinese herb theory and animal nutrition development trend at home and abroad, and provides scientific basis for the application of the Chinese herbal medicine in the livestock breeding production, meanwhile, the application scope of the Chinese herbal medicine in the livestock production is expanded, thereby the economic benefits of the livestock breeding are improved.

Description

A kind of Chinese herbal medicine weightening finish immunizing agent that is used for feed addictive
Technical field
The present invention relates to a kind of Chinese herbal medicine weightening finish immunizing agent that is used for feed addictive.
Background technology
Chinese herbal medicine is an importance of animal and veterinary Chinese herbal medicine application in recent years as feed addictive or mixed feeding medicament, also is a unique series of feed addictive, is subjected to extensive attention both domestic and external.Chinese herbal feed additive has both the effect of trophism and non-nutritive, its complex structure, and composition is various, is the polyfunctional internal factor of possessing of Chinese herbal feed additive.Chinese herbal medicine comes from the Nature, and except that the minority artificial growth, great majority are wild, and wide material sources are with low cost, are easy to apply.But since unreasonable as herbal prescription that feed addictive adds design, exist such as the digestion that is difficult to promote nutriment in the feed, absorption, even animal drug resistance problem occurs, directly have influence on growing of animal.
Summary of the invention
Technical problem to be solved by this invention provides the normal function of a kind of effective each tissue of raising letting animals feed, organ, system, thereby the ability that promote digestion, absorbs, drains promotes it to grow and the Chinese herbal medicine weighting agent that is used for feed addictive of drug resistance problem can not occur.
The present invention adopts following technical scheme:
The medicament that the present invention is made by following ratio of weight and number component:
Hawthorn 25-35, bark of official magnolia 8-12, dried immature fruit of citron orange 8-10, rhizoma atractylodis 8-12, Radix Astragali 15-20, medical stone 1.5-2.0, gynostemma pentaphylla 4-6, dried orange peel 0.8-1.5, Divine Comedy 0.8-1.5, Radix Glycyrrhizae 0.4-0.8, Fructus Hordei Germinatus 5-15, Ligusticum wallichii 0.4-0.8.
Good effect of the present invention is as follows: the present invention determines the research and development of its feeding Chinese herbal medicine weighting agent according to traditional Chinese herbal medicine theory of China and domestic and international Animal nutrition development trend, for the application of Chinese herbal medicine in its feeding production provides scientific basis, enlarge the range of application of Chinese herbal medicine in herding is produced simultaneously, improve the economic benefit that its feeding is cultured.
1. use test material of the present invention and method
Health-care agent is made up of hawthorn, the bark of official magnolia, the dried immature fruit of citron orange, rhizoma atractylodis, the Radix Astragali, medical stone, gynostemma pentaphylla, dried orange peel, Divine Comedy, Radix Glycyrrhizae, Fructus Hordei Germinatus, Ligusticum wallichii etc. 1.1 the present invention increases weight.Chinese medicine in the prescription is removed impurity, dried, pulverized 40 ~ 60 mesh sieves respectively, airtight preservation behind the mixing.
1.2 experimental animal
Healthy 4 the monthly age 40 of mutton sheeps, initial body weight is close, group difference is not remarkable.
1.3 test method
1.3.1 feeding experiment
The mutton sheep of selecting is divided into 5 groups, 8 every group.The conventional daily ration of control group fed, all the other 4 groups are added to said herbal medicine in the fine fodder by 0.5%, 1.0%, 1.5%, 2.0% 4 dosage respectively.Raise phase 7d in advance, just trying phase 50d.
1.3.2 digestion trial
Digest supersession test carries out in feeding experiment mid-term, formal phase 3d.Each group selects 2 of mutton sheeps to place in the digestion and metabolism cage, and it is free movable not have, and can freely drink water.Sooner or later the roughage of feeding every day, fine fodder at noon (being added with Chinese herbal medicine).Adopt endogenous indicator method.
Table 1 meat sheep feed prescription is formed
Component Account for fine fodder percentage (%) Component Account for percentage (%)
Corn dregs of beans cotton dregs wheat bran premix 54 15 2 25 4 Silage corn straw (doing) corn stalk (doing) alfalfas (doing) fine fodder: coarse fodder 62 30 8 36∶64
Table 2 mutton sheep fine fodder trophic level
Fine fodder Nutritional labeling
Thick protein (%) digestible energy (MJ/kg) calcium (%) phosphorus (%) 11.27 12.66 1.70 0.57
1.3.3 the mensuration of mutton sheep physiochemical indice
Feeding experiment finishes the previous day, choose 2 mutton sheeps for every group, early morning is jugular vein blood sampling 20ml under the condition on an empty stomach, be collected in centrifuge tube and tilt to leave standstill the 30min blood coagulation, the blood coagulation centrifuge tube is placed centrifuge, the centrifugal 15min separation of serum of 3500r/min is used for the mensuration of serum indexs such as GH to the Doffer pipe.
1.3.4 the safety testing of the pure Chinese herb feed additive of the present invention
Adopt horn method small white mouse acute toxinology experiment, select Kunming, 20 Jiankang kind small white mouse, be divided into 2 groups at random, 10 every group, every of test group gavages the Chinese herbal medicine decocting liquid of 0.5g every day, every physiological saline that gavages same dosage every day of control group.Observe 7d, it is all cutd open kill at last, observe internal organ and have or not ANOMALOUS VARIATIONS, and make comparisons, determine the toxicity size of prescription with control group.
2 test results and analysis
2.1 traditional Chinese medicine formula of the present invention is to the influence of mutton sheep weightening finish and feed conversion rate
Mutton sheep body weight and feed conversion rate the results are shown in Table 3, and from average daily gain and the mutton sheep feedstuff-meat ratio of experimental period, test group all improves than control group, the group of wherein adding medium-height grass dose 1.5% and 2.0% significant difference of comparing with control group.Illustrate that this Chinese herbal medicine test prescription effect is better than the mutton sheep feeding effect that does not add Chinese herbal medicine, can effectively improve the weightening finish of mutton sheep, accelerate the fast well-fattened of mutton sheep.
Table 3 Chinese herbal medicine weighting agent of the present invention is to the influence of mutton sheep body weight and feed conversion rate
Group Control group 0.5% addition 1.0% addition 1.5% addition 2.0% addition
Average daily gain (g) fine fodder/weightening finish 120.25 5.59 159.75° 4.69 185.25 4.11 194.25 3.80 199.00 3.76
2.2 traditional Chinese medicine formula of the present invention is to the influence of mutton sheep conversion rate of nitrogen and dry digestibility
Table 4 Chinese herb feed additive of the present invention is to the influence of mutton sheep nutrient digestibility
Group Control group 0.5% addition 1.0% addition 1.5% addition 2.0% addition
CP(%) ADF(%) NDF(%) DM(%) 0.69 73.86 69.79 81.57 0.71 74.51 73.47 85.03 0.71 76.25 74.42 84.22 0.73 75.20 76.35 86.86 0.78 74.61 74.40 87.95
Crude protein and dry digestibility are to weigh the important indicator that feed digests, utilizes situation in vivo.By table 4 result of the test, in meat sheep feed, add this Chinese herbal medicine, its crude protein and dry digestibility are all than the obvious improve of control group.
2.3 traditional Chinese medicine formula of the present invention is to the influence of mutton sheep blood parameters
Table 5 traditional Chinese medicine formula of the present invention is to the influence of mutton sheep blood parameters
Group Control group 0.5% addition 1.0% addition 1.5% addition 2.0% addition
GH(ng/ml) T 3(nmol/L) BUN(mmol/L) G(mmol/L) 0.39 185.00 9.15 9.11 0.49 195.70 9.12 8.68 0.52 285.53 6.72 8.37 0.58 438.23 6.03 8.33 0.63 228.70 5.75 8.17
By table 5 as seen, GH content is rising trend along with the increase of adding the medium-height grass dose in the mutton sheep serum; Chinese herbal medicine adds 1.5% group of T 3Level apparently higher than control group, improved 231.48% than control group respectively.Mutton sheep BUN level is all low than control group, on a declining curve, adds 1.5% and add 2.0% the group significant difference of comparing with control group.Each test group of serum glucose level all is lower than control group, and also presents downward trend.
2.4 traditional Chinese medicine formula safety testing result of the present invention
Result of the test shows, any bad reaction do not occur after gavaging small white mouse continuously in order to the dosage of 21.5g/kg body weight, and internal organ are not seen any ANOMALOUS VARIATIONS yet after the ptomatopsia, and the LD of this traditional Chinese medicine formula is described 50Be far longer than the 21.5g/kg body weight, pressed the acute toxinology experiment classification, this pure Chinese medicine weighting agent prescription belongs to non-poisonous material, is safe and reliable.
3 brief summaries
Chinese herbal medicine of the present invention is an importance of animal and veterinary Chinese herbal medicine application in recent years as feed addictive or mixed feeding medicament, also is a unique series of feed addictive, is subjected to extensive attention both domestic and external.The adding of this traditional Chinese medicine formula, mutton sheep is played flat benefit effect, promote digestion, the absorption of nutriment, accelerate the fast well-fattened of mutton sheep, play certain health care immunization simultaneously, can provide mutton sheep required various trace elements on the one hand, have effect clearing heat and detoxicating, invigorating the spleen to dry on the other hand, guarantee the stable of mutton sheep organismic internal environment, can concentrate more nutrition to be used for growth.
This prescription from drug mechanism, has rise and fall of yin and yang, the strengthening vital QI to eliminate pathogenic factors effect of adjusting animal body as pure medium-height grass feed addictive, the drug resistance problem can not occur in the application, and is nontoxic, obviously is better than antibiotic class medicine; From the metabolism angle, effectively improve the normal function of each tissue, organ, system, thereby the ability of promoting digestion, absorbing, draining promotes it to grow and can not.Therefore, the application prospect of Chinese herb feed additive is very wide, to the weightening finish health-care effect of mutton sheep and significantly, no hazard residue, toxic and side effect are little, and the medicine source is extensive, cheap, to mutton sheep is a desirable weightening finish health-care agent, and new thinking is opened up in the development that mutton sheep drylot feeding, half drylot feeding are fattened simultaneously.
The specific embodiment
The embodiment of the invention is as shown in the table:
Composition Content (ratio of weight and number)
Hawthorn 25 30 35
The bark of official magnolia 10 12 8
The dried immature fruit of citron orange 9 8 10
Rhizoma atractylodis 8 10 12
The Radix Astragali 15 18 20
Medical stone 1.8 1.5 2.0
Gynostemma pentaphylla 4 5 6
Dried orange peel 1.2 0.8 1.5
Divine Comedy 0.8 1.5 1.2
Radix Glycyrrhizae 0.4 0.6 0.8
Fructus Hordei Germinatus 10 5 15
Ligusticum wallichii 0.4 0.6 0.8
Chinese medicine in the above-mentioned prescription is removed impurity, dried, pulverized 40 ~ 60 mesh sieves respectively, airtight preservation behind the mixing.

Claims (1)

1. Chinese herbal medicine weightening finish immunizing agent that is used for feed addictive is characterized in that the medicament that it is made by following ratio of weight and number component:
Hawthorn 25-35, bark of official magnolia 8-12, dried immature fruit of citron orange 8-10, rhizoma atractylodis 8-12, Radix Astragali 15-20, medical stone 1.5-2.0, gynostemma pentaphylla 4-6, dried orange peel 0.8-1.5, Divine Comedy 0.8-1.5, Radix Glycyrrhizae 0.4-0.8, Fructus Hordei Germinatus 5-15, Ligusticum wallichii 0.4-0.8.
CN2007101852649A 2007-11-19 2007-11-19 A Chinese medicinal herb gaining immunopotentiator for feed additive Expired - Fee Related CN101156649B (en)

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Cited By (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102511687A (en) * 2011-12-26 2012-06-27 河南中医学院 Chinese herbal composite feed additive used for transportation stress recovery of beef cattle
CN101589769B (en) * 2009-07-07 2012-07-04 金陵科技学院 Dorking composite Chinese medicinal herb feed additive, preparation method thereof and use thereof
CN102715372A (en) * 2012-06-27 2012-10-10 灵山县园丰牧业有限公司 Sea duck traditional Chinese herbal medicine additive and application thereof
CN102754734A (en) * 2012-05-28 2012-10-31 鲁东大学 Chinese herbal livestock feed additive and application thereof
CN102940130A (en) * 2012-11-09 2013-02-27 石家庄学院 Broiler weight-increasing health agent
CN104187003A (en) * 2014-09-12 2014-12-10 阳谷雪龙肉羊养殖有限公司 Chinese herbal medicine growth promoting feed additive for mutton sheep and preparing method thereof
CN105104865A (en) * 2015-09-09 2015-12-02 广西桂林生物动力环保科技有限公司 Feed for ewe in lactation period and preparation method thereof
CN105341330A (en) * 2015-07-31 2016-02-24 河北北方牧业科技有限公司 Traditional Chinese medicine fattening additive
CN106551165A (en) * 2016-11-28 2017-04-05 贵州垄源农业开发有限公司 A kind of poultry is special to hybridize paper mulberry feed and preparation method thereof
CN106615857A (en) * 2017-02-09 2017-05-10 安徽菲扬农业科技有限公司 Black pig feed used in summer and preparation method thereof
CN107373083A (en) * 2017-09-07 2017-11-24 梁淑慧 A kind of ecological feed additive
CN108056273A (en) * 2018-01-10 2018-05-22 宝鸡神农农业科技有限公司 Chinese medicine health-care is prevented and the full price fattening pannage for the treatment of enteron aisle respiratory disease
CN108850431A (en) * 2018-07-26 2018-11-23 合肥仙之峰农业科技有限公司 A kind of goat-fattening feed and preparation method thereof
CN109619279A (en) * 2018-11-29 2019-04-16 广东高山动物药业有限公司 Pure Chinese medicine fattening feed additive and preparation method thereof and application method

Family Cites Families (1)

* Cited by examiner, † Cited by third party
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CN100584210C (en) * 2005-12-09 2010-01-27 王国平 Growth accelerating agent for pigs made from Chinese herb medicines, and its preparation method

Cited By (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101589769B (en) * 2009-07-07 2012-07-04 金陵科技学院 Dorking composite Chinese medicinal herb feed additive, preparation method thereof and use thereof
CN102511687A (en) * 2011-12-26 2012-06-27 河南中医学院 Chinese herbal composite feed additive used for transportation stress recovery of beef cattle
CN102511687B (en) * 2011-12-26 2013-04-03 河南中医学院 Chinese herbal composite feed additive used for transportation stress recovery of beef cattle
CN102754734A (en) * 2012-05-28 2012-10-31 鲁东大学 Chinese herbal livestock feed additive and application thereof
CN102715372A (en) * 2012-06-27 2012-10-10 灵山县园丰牧业有限公司 Sea duck traditional Chinese herbal medicine additive and application thereof
CN102715372B (en) * 2012-06-27 2013-08-28 灵山县园丰牧业有限公司 Sea duck traditional Chinese herbal medicine additive and application thereof
CN102940130A (en) * 2012-11-09 2013-02-27 石家庄学院 Broiler weight-increasing health agent
CN102940130B (en) * 2012-11-09 2014-12-03 石家庄学院 Broiler weight-increasing health agent
CN104187003A (en) * 2014-09-12 2014-12-10 阳谷雪龙肉羊养殖有限公司 Chinese herbal medicine growth promoting feed additive for mutton sheep and preparing method thereof
CN104187003B (en) * 2014-09-12 2016-08-31 阳谷雪龙肉羊养殖有限公司 Meat sheep Chinese herbal medicine feed additive for promoting growth and preparation method thereof
CN105341330A (en) * 2015-07-31 2016-02-24 河北北方牧业科技有限公司 Traditional Chinese medicine fattening additive
CN105104865A (en) * 2015-09-09 2015-12-02 广西桂林生物动力环保科技有限公司 Feed for ewe in lactation period and preparation method thereof
CN106551165A (en) * 2016-11-28 2017-04-05 贵州垄源农业开发有限公司 A kind of poultry is special to hybridize paper mulberry feed and preparation method thereof
CN106615857A (en) * 2017-02-09 2017-05-10 安徽菲扬农业科技有限公司 Black pig feed used in summer and preparation method thereof
CN107373083A (en) * 2017-09-07 2017-11-24 梁淑慧 A kind of ecological feed additive
CN108056273A (en) * 2018-01-10 2018-05-22 宝鸡神农农业科技有限公司 Chinese medicine health-care is prevented and the full price fattening pannage for the treatment of enteron aisle respiratory disease
CN108850431A (en) * 2018-07-26 2018-11-23 合肥仙之峰农业科技有限公司 A kind of goat-fattening feed and preparation method thereof
CN109619279A (en) * 2018-11-29 2019-04-16 广东高山动物药业有限公司 Pure Chinese medicine fattening feed additive and preparation method thereof and application method

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