CN101127792A - Mobile communication terminal with temperature compensation function in biological information measurement - Google Patents

Mobile communication terminal with temperature compensation function in biological information measurement Download PDF

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Publication number
CN101127792A
CN101127792A CNA200610111634XA CN200610111634A CN101127792A CN 101127792 A CN101127792 A CN 101127792A CN A200610111634X A CNA200610111634X A CN A200610111634XA CN 200610111634 A CN200610111634 A CN 200610111634A CN 101127792 A CN101127792 A CN 101127792A
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temperature
mobile communication
communication terminal
biological information
sensor
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CNA200610111634XA
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CN101127792B (en
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裵柄宇
李星东
石洪成
刘珍雅
李起元
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Infopia Co Ltd
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Infopia Co Ltd
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Abstract

The utility model relates to a mobile communication terminal with temperature compensation function used in biological information measurement, which comprises a biosensor socket, wherein, a biosensor detecting the biological information of an object directly is inserted into the socket; a temperature measurement unit for measuring temperature; and a controller. The biological information input by the biosensor is analyzed by analysis data stored and is temperature corrected by the temperature measurement unit, wherein, the temperature of the target object is measured by the temperature measurement unit without direct contact to the target object.

Description

Be used in the mobile communication terminal in the biological information measurement with temperature compensation function
Technical field
The present invention relates to a kind of mobile communication terminal that is used in biological information (bio-information) measurement with temperature compensation function.
Background technology
Biology sensor is to be used for device that the analyte that has made up biologic components and physical chemistry detector parts is detected.
Biology sensor is a kind of biochemical sensor, can optionally detect with measuring samples in chemical substance, particularly detect organic compound, the concrete composition of enzyme or antibody or microbe for example, and these are to the predetermined substance sensitivity.Biochemical sensor is used to detect and measure the organic compound that the abiochemistry transducer that uses so far is difficult to detect.
First sensitive mechanism of biology sensor is as follows.
Biology sensor detects organism by senser, the concrete composition of enzyme or antibody or microbe for example, and the chemical substance quantity (or concentration) that senser is detected converts voltage or current value to by converter (transduucer) and electrode.
In addition, biology sensor can be divided into enzyme sensor, microbiological sensor and immunosensor.Enzyme sensor and microbiological sensor use at present.The most extensive example of commercial biology sensor is an enzyme sensor, and it utilizes zymoprotein only to act on the singularity or the response of particular substrate molecule.
The example of the enzyme sensor of having developed or having used at present comprises the glucose sensor of the blood sugar that is used to detect the diabetic, as the urea sensor that is used for biology artificial kidney haemodialysis control of blood urea concentration sensor and as the uric acid sensor of gout patient's blood uric acid concentration transducer.In addition, also develop the multifunctional enzyme transducer, be used for detecting simultaneously the concentration of two or more chemical substance.An example of multifunctional enzyme transducer is the freshness transducer, determines the freshness of fish or meat by the concentration of measuring chemical substance more than three kinds or three kinds simultaneously.
Microbiological sensor is used for for example process management of alcoholic fermentation and glutamic acid fermentation of fermentation industry, perhaps is used for the measurement of the BOD (biochemistry oxygen demand) as water pollution index.In addition, even sensitiveness is lower than microbiological sensor, use big organic biology sensor to begin one's study such as fish.
Use antibody to be used for medical diagnosis on disease as the immunosensor of responsive element.For example, developed the immunosensor with antibody recently, antibody is corresponding to as the distinctive mark of the cancer of responsive element.This immunosensor can be used for the earlier detection of AIDS (Acquired Immure Deficiency Syndrome).
Developed a kind of undersized semiconductor biology sensor recently, it has the enzyme of film shape on little semiconductor chip.If the semiconductor biology sensor drops into actual the use, just can be inserted with and directly measure blood part and other composition in the body, and can be more prone to and carry out quickly the synchro measure of number of chemical material.
The sensitive mechanism of biology sensor is as follows.
Biology sensor is analyzed reflection wavelength, and reflection wavelength and tentation data table is compared by the ripple of optical spectroscopy to target object emission preset range wavelength.Used different wavelength range depends on the type of target object.
When using biology sensor to measure organism information, temperature influences blood sugar level, cholesterol levels and hepatic metabolism thing level greatly.Therefore, for accurate measurement, need be to temperature-compensating.
Blood glucose measurement based on above-mentioned first mechanism has following feature.
Diabetic's blood sugar level continues to change owing to excessive exercise and diet and complication, therefore need monitor their blood sugar level always.Blood glucose monitor has multiple, for example monitors the medical treatment device of blood sugar level, and the mobile phone that is equipped with blood glucose monitor.
Fig. 1 is the mobile communication terminal that is equipped with traditional blood glucose monitor.
The biology sensor 1 that the enzyme that blood sugar is responded is housed is inserted the biology sensor socket 5 of the battery pack 2 of the mobile communication terminal 10 that is equipped with blood glucose monitor.Mobile communication terminal 10 passes through main body 8 measuring blood levels, and shows this blood sugar level on display unit 9.
Korean patent application 2003-96652 has disclosed a kind of mobile communication terminal that is equipped with traditional blood glucose monitor.According to this application, after the strip transducer that will have the enzyme that glucose is responded inserts mobile communication terminal, blood is injected the strip transducer.Replacedly, can in the strip transducer that has with the enzyme of glucose response, inject blood after, the strip transducer is inserted mobile communication terminal.Glucose and enzyme be reaction each other on the strip transducer, produces electronics.Electronics is by current sensor senses.Current sensor senses flows through the electric current of two terminals, and current conversion is become digital signal, to be suitable for the input terminal of mobile station modems (MSM).When digital signal was input to MSM, based on data (based on the current/voltage relation of the reagent code) processing digital signal of memory cell stores, and this digital signal was presented on LCD (LCD) equipment as blood sugar level.
But, because therefore glucose and the reaction pair responsive to temperature of enzyme in mobile communication terminal exist following problem:
The first, because the heat that mobile communication terminal itself produces, mobile communication terminal can not keep temperature constant, therefore impossible measuring blood level;
The second, owing to can not detect the reaction temperature of glucose and enzyme, therefore can not the measuring blood level.
Summary of the invention
The invention provides a kind of mobile communication terminal that is used in the biological information measurement with temperature compensation function, it measures the reaction temperature of glucose and enzyme, and based on measuring the blood sugar level that the temperature correction mobile communication terminal is measured, thereby accurately measure the biological information of temperature influence, for example blood sugar level.
According to an aspect of the present invention, provide a kind of mobile communication terminal with temperature compensation function that is used in the biological information measurement, this mobile communication terminal comprises the biology sensor socket, wherein is inserted with the biology sensor of the biological information of direct detected object; Measure the temperature measurement unit of temperature; And controller, biological information based on the analysis data analysis biology sensor input of storing, and the described biological information of temperature correction of utilizing temperature measurement unit to measure, wherein temperature measurement unit is in the direct temperature of measurement target object under the situation of contact target object not.
According to the mobile communication terminal that is used in the biological information measurement of the present invention with temperature compensation function, use non-contact temperature sensor to measure the temperature of biology sensor shell, and the biological information of proofreading and correct temperature influence, for example blood sugar level, cholesterol levels and hepatic metabolism thing level.
Described biology sensor can use and the enzyme of glucose, cholesterol, hepatic metabolism thing and analog reaction.
With the enzyme of glucose response can be glucose oxidase and glucose dehydrogenase.
Described temperature measurement unit can be a non-contact temperature sensor.
Described non-contact temperature sensor can be an infrared temperature sensor.
The described mobile communication terminal with temperature compensation function that is used in the biological information measurement when using cholesterol to measure biology sensor replacement glucose measurement biology sensor, can be used to proofread and correct cholesterol levels.
The described mobile communication terminal with temperature compensation function that is used in the biological information measurement when using the hepatic metabolism thing to measure biology sensor replacement glucose measurement biology sensor, can be used to proofread and correct hepatic metabolism thing level.
The method that the described mobile communication terminal with temperature compensation function that is used in the biological information measurement of use according to the present invention is measured biological information comprises, measure the temperature of biology sensor shell with the non-contact temperature sensor that is combined in the mobile communication terminal, and use this temperature as enzyme reaction temperature with based on the numerical value in this enzyme reaction temperature correction data table.
The described method that is used in the mobile communication terminal measuring blood with temperature compensation function in the biological information measurement of use according to the present invention can also comprise, after carrying out the mobile communication terminal basic function, turn back to the operation that has determined whether to select biological information measurement pattern (blood glucose measurement pattern).
Quantity of blood expressed can be 1 to 10 microlitre.
Except using cholesterol sensor replacement glucose sensor, the method for proofreading and correct cholesterol levels can be identical with the correction method of glucose level.
Except using hepatic metabolism thing transducer replacement glucose sensor, the method for proofreading and correct hepatic metabolism thing level can be identical with the correction method of glucose level.
Description of drawings
By describing representative embodiments of the present invention with reference to the accompanying drawings in detail, it is clearer that above and other features and advantages of the present invention will become.In the accompanying drawings:
Fig. 1 is the mobile communication terminal with traditional blood glucose monitor;
Fig. 2 is the mobile communication terminal with temperature compensation function in the biological information measurement of being used in according to one embodiment of the present invention;
Fig. 3 is the block diagram that is used in the mobile communication terminal with temperature compensation function in the biological information measurement according to one embodiment of the present invention; And
Fig. 4 is the flow chart that is used in the mobile communication terminal with temperature compensation function in the biological information measurement according to one embodiment of the present invention.
Embodiment
Describe representative embodiments of the present invention below with reference to the accompanying drawings in detail.
Fig. 2 is the mobile communication terminal with temperature compensation function in the biological information measurement of being used in according to one embodiment of the present invention.
Be equipped with the mobile communication terminal 20 that is used for measuring blood level, cholesterol levels and hepatic metabolism thing level of monitor, use non-contact temperature sensor 13 to measure the temperature of biology sensor shell 14.Preferably, non-contact temperature sensor 13 is an infrared sensor.
Biology sensor 11 is inserted in the biology sensor socket 15 in the battery pack 12.The main body 18 of this mobile communication terminal 20 is self temperature correction temperature to biology sensor shell 14, measuring blood level, cholesterol levels and hepatic metabolism thing level, and show measurement results at display unit 19.
Fig. 3 is the block diagram that is used in the mobile communication terminal with temperature compensation function in the biological information measurement according to one embodiment of the present invention.
Power supply 210 provides electric power for the biological information measurement unit of the mobile communication terminal of serviceability temperature compensation.The power supply 210 main batteries that use.
Temperature measurement unit 220 is contactless, measures the temperature of rectangular sensor outer housing.
Rectangular transducer with biological information detector is inserted in the mobile communication terminal by rectangular sensor socket 230.
Current measuring unit 240 receives electric power, has two terminals, and detects electric current based on the concentration of the target substance between two terminals and change.
Signal converter (ADC) 250 becomes digital signal with the current conversion that detects.
Described biological information can detect with optical spectroscopy, rather than electrochemical process.Described optical spectroscopy comprises that the ripple with the preset range wavelength shines target object, analyzes reflection wavelength, reflection wavelength and tentation data table are compared, and definite target object.The preset range wavelength changes according to the type of target object.
Microprocessor 260 receiving digital signals, and the output control signal is to receive described tables of data and to obtain the concentration data of target substance from digital signal.
Memory cell 270 storage with about the reagent code and based on the tables of data of the relation of the current/voltage of temperature, and this tables of data is outputed to microprocessor 260 according to described control signal from microprocessor 260.
The display unit 280 of mobile communication terminal receives described concentration data from microprocessor 260, and shows this concentration data.
Fig. 4 is the flow chart that is used in the mobile communication terminal with temperature compensation function in the biological information measurement according to one embodiment of the present invention.
Starting this mobile communication terminal (S310) afterwards, judge whether this mobile communication terminal is in blood glucose measurement pattern (S320).If be not in the blood glucose measurement pattern, then this mobile communication terminal is carried out general utility functions (S400).
Use described non-contact temperature sensor to measure the temperature of described rectangular sensor outer housing (S330).
Described rectangular transducer is inserted in the rectangular sensor socket of mobile communication terminal (S340).
Collect blood and blood is injected into rectangular transducer (S350).
The electric current (S360) that the electronics that detection is produced by the reaction between glucose (blood sugar) and the glucose oxidase forms between two terminals.
Detected current conversion is become digital signal (S370).
From digital signal, obtain the concentration data of expression blood sugar level, and the tables of data (S380) that compensates rectangular sensor outer housing temperature.
On display unit, show this concentration data (S390).
After this, turn back to operation S320, judge whether this mobile communication terminal is in the blood glucose measurement pattern.
When non-selected blood glucose measurement pattern, this mobile communication terminal is carried out general utility functions (S400), and turns back to operation S320.
Except using cholesterol sensor and hepatic metabolism thing sensor measurement cholesterol levels and hepatic metabolism thing level respectively, the method for measuring and proofreading and correct cholesterol levels, hepatic metabolism thing level is identical with measurement and correction method of glucose level.
Can know from top description and to find out, because the described mobile communication terminal with temperature compensation function that is used in the biological information measurement uses non-contact temperature sensor to measure temperature, and the temperature of the biological information measurement of compensation mobile communication terminal, therefore can measure thermally sensitive various biological substance exactly.
Though described the present invention with reference to representative embodiment, one of ordinary skill in the art it should be understood that under the situation of the scope of the invention that does not depart from the claim qualification, can make the different variations of form and details.

Claims (4)

1. mobile communication terminal that is used in the biological information measurement with temperature compensation function, this mobile communication terminal comprises: the biology sensor socket wherein is inserted with the biology sensor of the biological information of direct detected object; Measure the temperature measurement unit of temperature; And controller, based on the biological information of the analysis data analysis biology sensor input of storing, and the described biological information of temperature correction of utilizing temperature measurement unit to measure,
Wherein temperature measurement unit is in the direct temperature of measurement target object under the situation of contact target object not.
2. mobile communication terminal according to claim 1, wherein said biology sensor comprises glucose oxidase or glucose dehydrogenase.
3. mobile communication terminal according to claim 1, wherein said temperature measurement unit are non-contact temperature sensor.
4. mobile communication terminal according to claim 3, wherein said non-contact temperature sensor are infrared temperature sensor.
CN200610111634XA 2006-08-18 2006-08-18 Mobile communication terminal with temperature compensation function in biological information measurement Expired - Fee Related CN101127792B (en)

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Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104215264A (en) * 2013-05-31 2014-12-17 盛思锐股份公司 Portable electronic device with integrated temperature sensor being compensated by other sensing data
CN104838264A (en) * 2012-09-11 2015-08-12 康奈尔大学 Apparatus and method for point-of-collection measurement of biomolecular reaction
WO2016131358A1 (en) * 2015-07-22 2016-08-25 中兴通讯股份有限公司 Home gateway, communication management method and communication system thereof
CN109722845A (en) * 2017-10-31 2019-05-07 上海小吉互联网科技有限公司 A kind of independent washing methods for launching enzyme preparation
CN113545779A (en) * 2020-04-23 2021-10-26 智准生医科技股份有限公司 Biological information sensing patch

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1322949A (en) * 2001-06-27 2001-11-21 李仁方 Blood sugar test set
KR100472092B1 (en) * 2002-05-14 2005-03-08 주식회사 헬스피아 A blood sugar test device using a wireless phone and a method to transmit the blood sugar level to internet server
KR20050037903A (en) * 2003-10-20 2005-04-25 케이제이헬스케어 주식회사 Mobile having a function of detecting glucose and system for medical checkup using the mobile and method thereof

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104838264A (en) * 2012-09-11 2015-08-12 康奈尔大学 Apparatus and method for point-of-collection measurement of biomolecular reaction
CN104215264A (en) * 2013-05-31 2014-12-17 盛思锐股份公司 Portable electronic device with integrated temperature sensor being compensated by other sensing data
CN104215264B (en) * 2013-05-31 2018-01-16 盛思锐股份公司 Portable electric appts with integrated temperature sensor
WO2016131358A1 (en) * 2015-07-22 2016-08-25 中兴通讯股份有限公司 Home gateway, communication management method and communication system thereof
CN109722845A (en) * 2017-10-31 2019-05-07 上海小吉互联网科技有限公司 A kind of independent washing methods for launching enzyme preparation
CN109722845B (en) * 2017-10-31 2020-12-29 上海小吉互联网科技有限公司 Washing method for independently adding enzyme preparation
CN113545779A (en) * 2020-04-23 2021-10-26 智准生医科技股份有限公司 Biological information sensing patch

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