CN101095791A - Chinese patent drug for treating diabetic neurogenic bladder - Google Patents
Chinese patent drug for treating diabetic neurogenic bladder Download PDFInfo
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- CN101095791A CN101095791A CN 200710118344 CN200710118344A CN101095791A CN 101095791 A CN101095791 A CN 101095791A CN 200710118344 CN200710118344 CN 200710118344 CN 200710118344 A CN200710118344 A CN 200710118344A CN 101095791 A CN101095791 A CN 101095791A
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Abstract
The invention relates to a Chinese medicament for treating diabetic neurogenic bladder which is prepared from more than ten kinds of Chinese medicinal herbs including achyranthes and cyathula root, climbing fern spore, lysimachia christinae and white peony root. The medicament has the advantages of assured curative effect, safe and convenient application, no toxic and side effects, and low price.
Description
Technical field
The present invention relates to a kind of Chinese patent medicine for the treatment of diabetic neurogenic bladder, is that a kind of diabetic neurogenic bladder for the treatment of is the Chinese patent medicine of raw material with the Chinese herbal medicine.Belong to the field of Chinese medicines.
Background technology
Diabetic neurogenic bladder is meant the maincenter of bladder or the urinary dysfunction that peripheral neuropathy causes, is called neurogenic bladder, is called cord bladder, nervous bladder functional disorder or atonic bladder again.The sickness rate of diabetic neurogenic bladder is 27%～85%.Because dysuria, easily cause the intractable urinary tract infection, increase the weight of diabetes so that influence renal function, be one of reason of diabetics death.According to the urine leaching glass not to the utmost, it is similar to " stranguria ", " difficulty in urination " in the Chinese medicine to urinate puckery symptom such as unfavorable.Pouring is meant that frequent micturition is short puckery, the sound of rain pattering not to the utmost, urethra is unfavorable, the cramp and pain in the lower abdomen person." Elementary Medicine ": " drench, whether difficulty and pain in micturition desired to go or not, and do not go to come again, drips constantly." can be divided into stranguria caused by urinary stone according to different performances clinically, qi stranguria, stranguria with blood, stranguria marked by chyluria, five kinds of strangurias caused by overstrain etc. are generically and collectively referred to as " five types of stranguria ".The traditional Chinese medical science is divided disease type Coryza Treated by Syndrome Differentiation clinically, obtains very good effect.Invent a kind of not only safety but also effective Chinese medicine preparation, be significant.
Summary of the invention
The present invention develops in conjunction with the latest modern technological scientific achievement on the basis of traditional tcm syndrome differentiation and treatment.The purpose of this invention is to provide a kind of Chinese patent medicine for the treatment of diabetic neurogenic bladder.Have determined curative effect, safe ready, have no side effect, cheap characteristics.
The present invention is made by the following weight proportion raw material:
1.00～4.0 parts of 1.5～6 parts of Folium Pyrrosiaes of 1.5～6 portions of Herba Lysimachiaes of Radix Cyathulae
1.00～4.0 parts of 1.0～4 parts of Radix Angelicae Sinensis of 1.0～4 portions of Rhizoma Cyperis of Pericarpium Citri Reticulatae
0.10～2.0 part of 0.1～2 part of Semen Abutili of 1.0～4 parts of Radix Et Rhizoma Rhei of the Radix Paeoniae Alba
0.05～0.4 part of 0.1～2 part of Succinum powder of 0.1～2 part of Spora Lygodii of Semen Vaccariae.
The weight proportion of each raw material of optimization formula of the present invention is:
1.5～2.5 parts of 2.5～3.5 parts of Folium Pyrrosiaes of 2.5～3.5 portions of Herba Lysimachiaes of Radix Cyathulae
1.5～2.5 parts of 1.5～2.5 parts of Radix Angelicae Sinensis of 1.5～2.5 portions of Rhizoma Cyperis of Pericarpium Citri Reticulatae
0.5～1.5 part of 0.5～1.5 part of Semen Abutili of 1.5～2.5 parts of Radix Et Rhizoma Rhei of the Radix Paeoniae Alba
0.1～0.3 part of 0.5～1.5 part of Succinum powder of 0.5～1.5 part of Spora Lygodii of Semen Vaccariae.
The weight proportion of each raw material of optimum formula of the present invention is:
2 parts of 3 parts of Folium Pyrrosiaes of 3 portions of Herba Lysimachiaes of Radix Cyathulae
2 parts of 2 parts of Radix Angelicae Sinensis of 2 portions of Rhizoma Cyperis of Pericarpium Citri Reticulatae
1 part of 1 part of Semen Abutili of 2 parts of Radix Et Rhizoma Rhei of the Radix Paeoniae Alba
0.2 part of 1 part of Succinum powder of 1 part of Spora Lygodii of Semen Vaccariae.
Drug action mechanism among the present invention is as follows:
Sweet, the little hardship of the Radix Cyathulae property of medicine, flat.Return liver, kidney channel.Has blood circulation promoting and blood stasis dispelling, the effect of expelling wind and removing dampness.Can treat the blood stasis amenorrhea, difficult labour, retention of placenta, postnatal blood stasis stomachache, pyretic stranguria, stranguria caused by urinary stone, dysmenorrhea, rheumatism lumbocrural pain, traumatic injury etc.(the 301st page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Sweet, the little hardship of the Herba Lysimachiae property of medicine, cold.Return liver, gallbladder, kidney, urinary bladder channel.Have heat clearing away, dampness removing, treating stranguria, calculus, antidotal effect.Can treat jaundice due to damp-heat, pyretic stranguria, oedema due to nephritis, liver, gallbladder and urinary system calculus, pyretic toxicity carbuncle, venom etc.(the 1967th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Folium Pyrrosiae property of medicine hardship, sweet, cold.Return lung, kidney, urinary bladder channel.Has relieving stranguria by diuresis, removing heat from the lung and dissipating phlegm, the effect of cooling blood for hemostasis.Can treat stranguria, edema, dysuria, the expectorant heat syndrome cough is breathed heavily, and spitting of blood is spitted blood epistaxis, metrorrhagia and traumatic hemorrhage etc.(the 811st page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Pericarpium Citri Reticulatae property of medicine suffering, hardship, temperature.Return spleen, stomach, lung meridian.Having in the accent of regulating the flow of vital energy stopping nausea and vomiting by lowering the adverse flow of QI, the effect of drying dampness to eliminate phlegm.It is full vexed to treat chest and diaphragm, abdominal distention, anorexia, vomiting, hiccup; Cough with copious phlegm.Acute mastitis from the beginning of etc.(the 1668th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Rhizoma Cyperi property of medicine suffering, sweet, little hardship, flat.Return liver, tri-jiao channel.Has the resolving depression of regulating the flow of vital energy, regulating menstruation, antiabortive effect.Can treat distending pain over the hypochondrium, distending pain of the breast, hernia pain, menoxenia, gastral cavity abdomen feeling of fullness pain, belch acid regurgitation, vomiting and nausea, abdominal pain during menstruation, bleeding not during menses, frequent fetal movement etc.(the 2341st page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Radix Angelicae Sinensis property of medicine is sweet, hot, bitter, temperature.Return liver, the heart, spleen channel.Having enriches blood invigorates blood circulation, menstruction regulating and pain relieving, the effect of moisturizing laxation.Can treat all cards of blood deficiency, menoxenia, amenorrhea, dysmenorrhea ， mass in the abdomen knot is poly-, metrorrhagia, asthenia cold abdominalgia, flaccidity syndrome and arthralgia syndrome, numbness of the skin, the dryness of the intestine dyschezia, heavy after the bloody dysentery, ulcer sores, injury from falling down etc.(the 1210th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Radix Paeoniae Alba property of medicine hardship, acid are slightly cold.Return liver, spleen channel.Have and nourish blood and seek relieving spasm to stop pain, the effect of yin fluid astringing suppressing the hyperactive liver.Can treat the blood deficiency cold and heat, epigastric pain, hypochondriac pain, limb spasm pain, dysmenorrhea, menoxenia, metrorrhagia, spontaneous perspiration, night sweat, dysentery is had loose bowels, and it is dizzy to have a headache etc.(the 948th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Radix Et Rhizoma Rhei property of medicine hardship, cold.Return stomach, large intestine, liver, spleen channel.Have attack stagnant, clearing away damp-heat, pathogenic fire purging, removing heat from blood, blood stasis dispelling, antidotal effect.Can treat the food stagnation constipation, the accumulation of heat feeling of stuffiness in chest; Damp-heat dysentery, jaundice, gonorrhea, edema abdominal distention, dysuria; Conjunctival congestion, laryngopharynx swelling and pain, aphtha of the mouth and tongue, gastropyretic vomiting; Spit blood, spitting of blood, epistaxis is had blood in stool, hematuria; Blood-retention, amenorrhea, the stagnant stomachache of the stasis of blood in puerperal ， lumps in the chest and abdomen, traumatic injury; Pyretic toxicity carbuncle and ulcer, erysipelas is scalded etc.(the 141st page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Semen Abutili property of medicine is sweet, and is cold.Return large intestine, small intestinal, urinary bladder channel.Has relieving stranguria by diuresis, the effect of laxation relieving constipation.Can treat gonorrhea, edema, constipation, galactozemia etc.(the 1053rd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Semen Vaccariae property of medicine hardship, flat.Return liver, stomach warp.Has promoting blood circulation to restore menstrual flow, the effect of stimulating milk secretion eliminating carbuncle.Can treat women's abdominal pain during menstruation, amenorrhea, galactostasis, acute mastitis, carbuncle etc.(the 426th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Spora Lygodii property of medicine is sweet, light, and is cold.Return bladder, small intestinal, spleen channel.Has relieving stranguria by diuresis, the effect of heat-clearing and toxic substances removing.Can treat the pyretic stranguria stranguria with blood, the sand Stranguria nebulousurine, woman's leukorrhagia, the water damp-edema is full, damp-heat dysentery, jaundice due to damp-heat, the double hematemesis and epistaxis of controlling, traumatic hemorrhage etc.(the 2744th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Succinum powder property of medicine is sweet, and is flat.GUIXIN, liver, urinary bladder channel.Has tranquillizing the mind by relieving convulsion, dissipating blood stasis hemostasis, relieving stranguria by diuresis, the effect that removing nebula makes eye bright.But Cure for insomnia, palpitation with fear, infantile convulsion, epilepsy, the blood stasis amenorrhea, puerperal abdonimal pain ， lumps in the chest and abdomen, the stranguria with blood hematuria, order is given birth to cataracta etc.(the 3188th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The present invention follows the principles of formulating prescriptions of the traditional Chinese medical science " monarch ", is monarch drug with Radix Cyathulae, Spora Lygodii, Herba Lysimachiae and Succinum powder; With Folium Pyrrosiae, Pericarpium Citri Reticulatae, Rhizoma Cyperi, Radix Angelicae Sinensis and the Radix Paeoniae Alba is ministerial drug; With Semen Vaccariae, Radix Et Rhizoma Rhei and Semen Abutili is adjuvant.All medicines are harmonious, and are total to the tool blood circulation promoting and dispersing pathogen accumulation, the effect of tonneau water channel.The treatment diabetic neurogenic bladder has determined curative effect, has no side effect taking convenience, cheap characteristics.
Clinical drug of the present invention uses the result to show that following advantage is arranged:
1, the Chinese herbal medicine each component selected for use of the present invention meets the regulation of Pharmacopoeia of People's Republic of China, utilizes the comprehensive function treatment diabetic neurogenic bladder of the Chinese medicine of respectively distinguishing the flavor of, and is nontoxic to human body.Show that through the acute and chronic toxicity test of animal the animal of being tested does not see any toxic reaction, its main organs does not have tangible change yet, and safety of medicine is reliable.
2, rich in proteins in the medicine of the present invention, glucose, glucuronic acid, volatile oil, pectin, fructose, organic acid, lecithin, vitamin, aminoacid also contains various trace elements such as Saponin, plant sterol and calcium, is beneficial to absorption of human body, health invigorating.
3, the present invention not only can effectively treat diabetic neurogenic bladder, and the prevention of diabetic neurogenic bladder is also had good effect, and the treatment diabetic neurogenic bladder has determined curative effect, has no side effect taking convenience, cheap characteristics.
For showing the therapeutic effect of medicine of the present invention, as follows through clinical test results to the treatment diabetic neurogenic bladder; Treatment diabetic neurogenic bladder underwent 16 examples.Take the embodiment decoction, each 1 bag, two to three times on the one, take half an hour ante cibum.Three months is a course of treatment, take continuously three the course of treatment observe the curative effect.6 examples of fully recovering account for 37.5%, and 8 examples that take a turn for the better account for 50%, and invalid 2 examples account for 12.5%, and total effective rate reaches 87.5%.After three course of therapy, patient does not have any untoward reaction, and three big routine tests and hepatic and renal function detect no abnormal.
The specific embodiment
The embodiment decoction takes by weighing raw material by following weight:
2 parts of 3 parts of Folium Pyrrosiaes of 3 portions of Herba Lysimachiaes of Radix Cyathulae
2 parts of 2 parts of Radix Angelicae Sinensis of 2 portions of Rhizoma Cyperis of Pericarpium Citri Reticulatae
1 part of 1 part of Semen Abutili of 2 parts of Radix Et Rhizoma Rhei of the Radix Paeoniae Alba
0.2 part of 1 part of Succinum powder of 1 part of Spora Lygodii of Semen Vaccariae.
Preparation method is to get above-mentioned raw materials to clean roguing, dries, and is ground into granule, soaks 1 hour, puts and decocts with water secondary in the multi-function extractor, adds up the water of 10 times of amounts of medical material for the first time, decocts 1.5～2 hours, gets decocting liquid, filters.Add up for the second time the water of 7 times of amounts of medical material, decocted 1～1.2 hour, get decocting liquid twice, filter, in the heat-sealing bag, 105 ℃ of high temperature sterilizes, packing is promptly.The decoction of the treatment diabetic neurogenic bladder that the present invention makes is that plastic packaging is packed, and every bag of 210ml is oral, one time one bag, every day two to three times.Three months is a course of treatment.
Claims (3)
1, a kind of Chinese patent medicine for the treatment of diabetic neurogenic bladder is characterized in that it is made by the following weight proportion raw material:
1.00～4.0 parts of 1.5～6 parts of Folium Pyrrosiaes of 1.5～6 portions of Herba Lysimachiaes of Radix Cyathulae
1.00～4.0 parts of 1.0～4 parts of Radix Angelicae Sinensis of 1.0～4 portions of Rhizoma Cyperis of Pericarpium Citri Reticulatae
0.10～2.0 part of 0.1～2 part of Semen Abutili of 1.0～4 parts of Radix Et Rhizoma Rhei of the Radix Paeoniae Alba
0.05～0.4 part of 0.1～2 part of Succinum powder of 0.1～2 part of Spora Lygodii of Semen Vaccariae.
2, a kind of Chinese patent medicine for the treatment of diabetic neurogenic bladder according to claim 1, wherein the weight proportion of each raw material is:
1.5～2.5 parts of 2.5～3.5 parts of Folium Pyrrosiaes of 2.5～3.5 portions of Herba Lysimachiaes of Radix Cyathulae
1.5～2.5 parts of 1.5～2.5 parts of Radix Angelicae Sinensis of 1.5～2.5 portions of Rhizoma Cyperis of Pericarpium Citri Reticulatae
0.5～1.5 part of 0.5～1.5 part of Semen Abutili of 1.5～2.5 parts of Radix Et Rhizoma Rhei of the Radix Paeoniae Alba
0.1～0.3 part of 0.5～1.5 part of Succinum powder of 0.5～1.5 part of Spora Lygodii of Semen Vaccariae.
3, a kind of Chinese patent medicine for the treatment of diabetic neurogenic bladder according to claim 1, wherein the weight proportion of each raw material is:
2 parts of 3 parts of Folium Pyrrosiaes of 3 portions of Herba Lysimachiaes of Radix Cyathulae
2 parts of 2 parts of Radix Angelicae Sinensis of 2 portions of Rhizoma Cyperis of Pericarpium Citri Reticulatae
1 part of 1 part of Semen Abutili of 2 parts of Radix Et Rhizoma Rhei of the Radix Paeoniae Alba
0.2 part of 1 part of Succinum powder of 1 part of Spora Lygodii of Semen Vaccariae.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200710118344 CN101095791A (en) | 2007-07-05 | 2007-07-05 | Chinese patent drug for treating diabetic neurogenic bladder |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200710118344 CN101095791A (en) | 2007-07-05 | 2007-07-05 | Chinese patent drug for treating diabetic neurogenic bladder |
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| Publication Number | Publication Date |
|---|---|
| CN101095791A true CN101095791A (en) | 2008-01-02 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 200710118344 Pending CN101095791A (en) | 2007-07-05 | 2007-07-05 | Chinese patent drug for treating diabetic neurogenic bladder |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103007229A (en) * | 2012-12-27 | 2013-04-03 | 陈淑香 | Medicine for treating neurogenic bladder |
| CN104971211A (en) * | 2014-04-02 | 2015-10-14 | 王嘉影 | Compound traditional Chinese medicine decoction used for treating diabetic neurogenic bladder disease |
-
2007
- 2007-07-05 CN CN 200710118344 patent/CN101095791A/en active Pending
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103007229A (en) * | 2012-12-27 | 2013-04-03 | 陈淑香 | Medicine for treating neurogenic bladder |
| CN103007229B (en) * | 2012-12-27 | 2013-11-27 | 陈淑香 | Medicine for treating neurogenic bladder |
| CN104971211A (en) * | 2014-04-02 | 2015-10-14 | 王嘉影 | Compound traditional Chinese medicine decoction used for treating diabetic neurogenic bladder disease |
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Open date: 20080102 |