CN101062060A - Method for preparing nanometer pearl powder - Google Patents
Method for preparing nanometer pearl powder Download PDFInfo
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- CN101062060A CN101062060A CNA2006100779815A CN200610077981A CN101062060A CN 101062060 A CN101062060 A CN 101062060A CN A2006100779815 A CNA2006100779815 A CN A2006100779815A CN 200610077981 A CN200610077981 A CN 200610077981A CN 101062060 A CN101062060 A CN 101062060A
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- margarita powder
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Abstract
The invention discloses a preparing method of nanometer pearl powder, which comprises the following steps: disintegrating pearl powder with air flow; producing the pearl powder with 2mum-10mum; placing into high-pressure vessel; charging into nitrogen; forcing; liquefying the nitrogen; soaking for 5-24 h in liquid nitrogen; getting the mixture; jetting the mixture into depression vessel with high speed; knocking the wall of the vessel severely; getting the nanometer grade pearl powder with single layer structure; drying; reclaiming. This method possesses low energy consumption and high efficiency, which is easy to be absorbed by human body.
Description
Technical field
The present invention relates to a kind of medical or Margarita powder processing technique field that food is used, particularly a kind of preparation method of nanometer pearl powder.
Background technology
Margarita is a kind of famous and precious Chinese crude drug, have calm the nerves, make eye bright, the effect of detoxifcation and aesthetic health care.Modern science the analysis showed that Margarita contains nearly 20 seed amino acids, 20 various trace elements, porphyrin and abundant calcium class.But Margarita has the hybrid nanostructured, and calcium carbonate sandwich one layer thickness of two-layer nepheline structure is several protein layers to tens nano thickness, and this makes Margarita have very high hardness and toughness, processes very difficult.The processing method of tradition Margarita powder, as elutriation and vibromill method, generally at tens microns, the absorption by human body utilization rate is lower for the particle diameter of the Margarita powder of gained, has the research report to show that the absorption by human body utilization rate is below 30%.In order to improve the absorption rate of human body to Margarita powder, people mainly solve the low problem of utilization rate by the approach of two aspects.Being the Margarita liquid of producing solubility on the one hand, is to prepare the more nanometer pearl powder of small particle diameter on the other hand.As in the patent document of the number of opening, disclosing the preparation method of soluble pearl powder for CN88105369 and CN1018615, but this method or with sour dissolved pearl powder, perhaps hydrolysis under High Temperature High Pressure has changed prototype structure and the composition of Margarita, can influence the effect of Margarita powder.The preparation method of nanometer pearl powder is disclosed in publication number is the patent document of CN1416821 and CN1582966A, but the particle size distribution too wide (10 to 1000nm) of the Margarita powder of the former gained, greater particle size Margarita powder particle to absorb efficient lower.Though and the latter can obtain the Margarita powder of particle diameter in 50 to 100 nanometers, the high pressure that it needs 50 to 150MPa destroys the prototype structure of Margarita powder easily, and the production cost height, realizes difficulty.
Summary of the invention
The invention provides a kind of pure natural property and integrity that can guarantee the Margarita powder composition, Margarita powder can be machined to the Margarita powder preparation method of nanoscale fineness again.
The technical solution adopted for the present invention to solve the technical problems is: a kind of preparation method of nanometer Margarita powder, realize that the step of this method comprises:
1. will place in the high-pressure bottle through the Pearl that comminution by gas stream is made about 2 μ m to 10 μ m, charge into nitrogen and pressurization makes liquefaction of nitrogen;
2. Pearl soaks in liquid nitrogen;
3. by pipeline with the mixture high velocity jet of liquid nitrogen and Margarita powder to pressure reduction vessel, mixture obtains the nanometer pearl powder of single layer structure through clashing, the particle diameter of Margarita powder is less than 100 nanometers;
4. dried recovered.
In the preparation method of described nanometer Margarita powder, the weight of liquid nitrogen be Margarita powder weight 5% to 20% between.
In the preparation method of described nanometer Margarita powder, Pearl soaks in liquid nitrogen, is forced into 32 in the high-pressure bottle to 38Mpa, and the time of immersion is 5 to 24 hours.
In the preparation method of described nanometer Margarita powder, the speed that mixture is injected in the pressure reduction vessel is 1000m/s to 3500m/s, and flow is 30L/h to 60L/h, and the mixture course of injection is cooled to-130 to-180 ℃.
The preparation method of described nanometer Margarita powder, a conduit is arranged at the high-pressure bottle bottom, and the conduit caliber is not less than 5cm, leads to pressure reduction vessel, and catheter nozzle is over against the pressure reduction vessel inwall, and the pressure in the pressure reduction vessel is kept to normal pressure.
The preparation method of described nanometer Margarita powder, a conduit is arranged at the high-pressure bottle bottom, the conduit caliber is not less than 5cm, lead to pressure reduction vessel, catheter nozzle wear-resisting baffle plate of a rustless steel in the pressure reduction vessel, distance about 50 be to 200mm, the built-in electric heater of plate washer, automatically be heated to 100 ℃, the pressure in the pressure reduction vessel is kept to normal pressure.
The present invention is directed to Margarita and have hard laminate structure, (thickness in monolayer is very thin, the thinnest tens nanometers are only arranged), Margarita powder granule behind comminution by gas stream still is made up of many thin layers, utilize liquid nitrogen that Margarita powder book layer is soaked into, after immersion liquid nitrogen Margarita powder ejects with flank speed, under the rapid decompression condition, can expand rapidly, peel off between Margarita bisque and the layer, and be cooled to-130 to-180 ℃ rapidly, form very frangible Margarita powder monolayer book sheet, behind Margarita powder monolayer book sheet high-speed impact pressure reduction vessel wall or the plate washer, be broken into nanometer pearl powder, thereby obtain the Margarita powder that particle diameter is 30 to 100 nanometers.
The preparation method energy consumption that the invention has the beneficial effects as follows nanometer Margarita powder is low, the efficient height; Needn't high temperature in the course of processing, so the Margarita powder nutritive loss is minimum, and natural flavour mountaineous constant; The Margarita powder particle diameter is 30 to 100 nanometers, and uniform particles, is easy to be absorbed by human consumption, also easily by skin absorbs, is suitable for medicine, nutrition and skin care item and uses as additive.
The specific embodiment
Pearl particles is crushed to 30-100 order granule through pulverizer, and being crushed to particle diameter through jet mill then is 2-15 μ m Margarita powder.
With above-mentioned particle diameter be the Margarita powder 100kg of 2-15 μ m to place volume be in the rustless steel high-pressure bottle of 150L, feed nitrogen pressure continuously to 32-36MP, nitrogen is liquefied at normal temperatures, the nitrogen quality of adding is 5-20kg.Keeping pressure soaked 6-10 hour.Be delivered in the pressure reduction vessel by pressure vessel bottom conduit (caliber is not less than 5cm) then, catheter nozzle wear-resisting baffle plate of a rustless steel in the pressure reduction vessel, the about 50-200mm of distance, the built-in electric heater of plate washer is heated to 100 ℃ automatically in case the plate washer temperature is low excessively.The pressure reduction vessel internal pressure is a normal pressure.The nozzle high velocity jet goes out contains Margarita powder air-flow rapid decompression in pressure reduction vessel, the Margarita powder particle temperature is reduced to-130 to-180 ℃ rapidly, become very frangible, the nitrogen of pearl powder particles sheet interlayer produces immense pressure when expanding, rapidly Margarita powder is burst into the monolayer fragment.The frangible fragment of low temperature obtains further fragmentation with huge speed (1000m/s to 3000m/s) impact baffle plate, becomes 30 to 100 nanometer Margarita powders, is collected by catcher.The product recovery rate of present embodiment is 99.0%, and the nanometer Margarita powder pick-up rate is 95.3%.Whole course of injection high-pressure bottle internal pressure remains at 32 to 36MPa, and shut-off nozzle when pressure is not enough gos up to 32 to 36MPa to treat the high-pressure bottle internal pressure.
The present invention does not change structure and the composition of Margarita, has improved the utilization rate of Margarita powder, and its technology is simple, is easy to suitability for industrialized production; The Margarita powder nutritive loss of processing is few, and particle diameter is little, is absorbed by human consumption easily, is particularly suitable for medicine, nutrition and skin care item and uses as additive.
Claims (8)
1, a kind of manufacture method of nanometer Margarita powder is characterized in that: the step of described method comprises: 1. will place in the high-pressure bottle through the Pearl that comminution by gas stream is made about 2 μ m to 10 μ m, charge into nitrogen and pressurization makes liquefaction of nitrogen;
2. Pearl soaks in liquid nitrogen;
3. by pipeline with the mixture high velocity jet of liquid nitrogen and Margarita powder to pressure reduction vessel, mixture obtains the nanometer pearl powder of single layer structure through clashing, the particle diameter of Margarita powder is less than 100 nanometers;
4. dried recovered.
2, the manufacture method of nanometer Margarita powder according to claim 1 is characterized in that: the weight of liquid nitrogen be Margarita powder weight 5% to 20% between.
3, the manufacture method of nanometer Margarita powder according to claim 1 is characterized in that: when Pearl soaks in liquid nitrogen, be forced into 32 in the high-pressure bottle to 38Mpa.
4, the manufacture method of nanometer Margarita powder according to claim 1 is characterized in that: the time that Pearl soaks in liquid nitrogen is 5 to 24 hours.
5, the manufacture method of nanometer Margarita powder according to claim 1 is characterized in that: the speed that mixture is injected in the pressure reduction vessel is 1000m/s to 3500m/s, and flow is 30L/h to 60L/h, and the mixture course of injection is cooled to-130 to-180 ℃.
6, the manufacture method of nanometer Margarita powder according to claim 1 is characterized in that: a conduit is arranged at the high-pressure bottle bottom, and the conduit caliber is not less than 5cm, leads to pressure reduction vessel, and catheter nozzle is over against the pressure reduction vessel inwall.
7, the manufacture method of nanometer Margarita powder according to claim 1, it is characterized in that: a conduit is arranged at the high-pressure bottle bottom, the conduit caliber is not less than 5cm, lead to pressure reduction vessel, catheter nozzle wear-resisting baffle plate of a rustless steel in the pressure reduction vessel, distance about 50 is to 200mm, and the built-in electric heater of plate washer is heated to 100 ℃ automatically.
8, according to the manufacture method of the described nanometer Margarita powder of one of claim 1 to 7, it is characterized in that: the pressure in the pressure reduction vessel is kept to normal pressure.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA2006100779815A CN101062060A (en) | 2006-04-28 | 2006-04-28 | Method for preparing nanometer pearl powder |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA2006100779815A CN101062060A (en) | 2006-04-28 | 2006-04-28 | Method for preparing nanometer pearl powder |
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| CN101062060A true CN101062060A (en) | 2007-10-31 |
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| CNA2006100779815A Pending CN101062060A (en) | 2006-04-28 | 2006-04-28 | Method for preparing nanometer pearl powder |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2010146308A1 (en) * | 2009-06-17 | 2010-12-23 | Jd Invest | Method for preparing mechanically structured mother-of-pearl by mechanosynthesis, mechanically structured mother-of-pearl produced thereby, and the applications thereof |
| CN102744136A (en) * | 2012-07-13 | 2012-10-24 | 四川厚德医药科技有限公司 | Preparation method for nanometre pearl powder |
| CN113663566A (en) * | 2021-08-23 | 2021-11-19 | 亳州市永刚饮片厂有限公司 | Pearl powder production process |
-
2006
- 2006-04-28 CN CNA2006100779815A patent/CN101062060A/en active Pending
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2010146308A1 (en) * | 2009-06-17 | 2010-12-23 | Jd Invest | Method for preparing mechanically structured mother-of-pearl by mechanosynthesis, mechanically structured mother-of-pearl produced thereby, and the applications thereof |
| FR2946888A1 (en) * | 2009-06-17 | 2010-12-24 | Mega Bio Pharma | PROCESS FOR THE PREPARATION OF MECANO-SYNTHESIS MECHANOSTRUCTURED NACRE, MECHANOSTRUCTURED NACRE SO OBTAINED AND ITS APPLICATIONS |
| CN102802687A (en) * | 2009-06-17 | 2012-11-28 | Jd投资 | Method For Preparing Mechanically Structured Mother-of-pearl By Mechanosynthesis, Mechanically Structured Mother-of-pearl Produced Thereby, And The Applications Thereof |
| US8485458B2 (en) | 2009-06-17 | 2013-07-16 | Jd Invest | Process for the preparation of nacre mechano-structured by mechanosynthesis, mechano-structured nacre thus obtained and uses thereof |
| CN102744136A (en) * | 2012-07-13 | 2012-10-24 | 四川厚德医药科技有限公司 | Preparation method for nanometre pearl powder |
| CN102744136B (en) * | 2012-07-13 | 2014-04-30 | 四川厚德医药科技有限公司 | Preparation method for nanometre pearl powder and prepared nanometer pearl powder |
| CN113663566A (en) * | 2021-08-23 | 2021-11-19 | 亳州市永刚饮片厂有限公司 | Pearl powder production process |
| CN113663566B (en) * | 2021-08-23 | 2023-10-31 | 亳州市永刚饮片厂有限公司 | Pearl powder production process |
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