CN101053653A - Traditional Chinese medicinal composition for treating endometriosis sterility - Google Patents

Traditional Chinese medicinal composition for treating endometriosis sterility Download PDF

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Publication number
CN101053653A
CN101053653A CNA2007100992308A CN200710099230A CN101053653A CN 101053653 A CN101053653 A CN 101053653A CN A2007100992308 A CNA2007100992308 A CN A2007100992308A CN 200710099230 A CN200710099230 A CN 200710099230A CN 101053653 A CN101053653 A CN 101053653A
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parts
rhizoma
chinese medicine
blood
portions
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CNA2007100992308A
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王信锁
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Beijing Yixintang Medicine Institute
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Beijing Yixintang Medicine Institute
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Abstract

The invention relates to a Chinese medicinal preparation for treating sterility caused by endometriosis comprising dozens of Chinese herbs including lindera root, angelica, zedoary and cyperirhizome. It can regulate qi, invigorate blood and dissolve stasis to promote conception. The invention is prepared by latest modern medical study result and based on traditional syndrome differentiation on TCM. It has confirmed efficacy and low price, being safe, besides no side or toxic effect will be caused.

Description

A kind of Chinese medicine preparation for the treatment of endometriosis infertility
Technical field
The present invention relates to a kind of Chinese medicine preparation for the treatment of endometriosis infertility, is that a kind of endometriosis infertility for the treatment of is the Chinese medicine preparation of raw material with the Chinese herbal medicine.Belong to the field of Chinese medicines.
Background technology
When endometriosis (abbreviation gynecopathy), the endometrial tissue that means the growth function appear at other positions of health beyond the cavity of uterus lining mucosa, be called endometriosis.Clinical manifestation is dysmenorrhea, menoxenia, infertile, sexual anhedonia etc., and all symptoms are carrying out property aggravation trend, and up to ovarian function failure, its symptom is just alleviated gradually, and focus absorbs gradually.Endometriosis is common gynaecopathia, influence 2.5%~15% the women of child-bearing age, acomia patient before menarche, Ectopic Endometrium tissue atrophy absorption gradually after the menopause, gestation or usability hormone suppress the development that ovarian function can temporarily stop this disease.1988~nineteen ninety leave hospital record statistics of U.S.'s state hospital, in 15~44 years old was in hospital the women, the endometriosis patient reached 32.4%.The eighties, China reported once that domestic sickness rate reached 10%.In recent years the incidence rate of primary disease has tangible increase trend, has become common gynecological disease, frequently-occurring disease, more and more is subjected to clinical attention.According to the clinical manifestation of this disease, belong to the traditional Chinese medical science " dysmenorrhea ", " mass in the abdomen ", " loss of fecundity " and categories such as " menoxenias ".Chinese medicine thinks, it is periodically hemorrhage that endometriosis is that ectopic inner membrance has, and accumulates in the part, and cause its surrounding tissue fibrosis, and this is " blood circulating out of vessels ", claims blood-retention or blood stasis.The traditional Chinese medical science is divided into qi stagnation and blood stasis type clinically, cold blood stasis type, and Qi deficiency blood stasis type, the stagnation of blood stasis and heat type, disease type Coryza Treated by Syndrome Differentiation such as blood stasis due to renal deficiency obtain very good effect.Invent a kind of not only safety but also effective Chinese medicine preparation, be significant.
Summary of the invention
The present invention develops in conjunction with the latest modern technological scientific achievement on the basis of traditional tcm syndrome differentiation and treatment.The purpose of this invention is to provide a kind of Chinese medicine preparation for the treatment of endometriosis infertility.Have determined curative effect, safe ready, have no side effect, cheap characteristics.
The present invention is made by the following weight proportion raw material:
1.0~4 parts of 1.0~4 parts of Cortex Moutans of 1.5~6 portions of Rhizoma Cyperis of the Radix Linderae
1.0~4 parts of 1.0~4 parts of Pollen Tyjphae of 1.5~6 parts of Rhizoma Chuanxiongs of Radix Angelicae Sinensis
0.1~2 part of 1.0~4 parts of Oletum Trogopterori of 1.5~6 parts of Radix Paeoniae Rubra of Rhizoma Curcumae
0.1~2 part of 0.1~2 part of Rhizoma Corydalis of 1.0~4 portions of Fructus Gardeniaes of Semen Persicae
The weight proportion of each raw material of optimization formula of the present invention is:
1.5~2.5 parts of 1.5~2.5 parts of Cortex Moutans of 2.5~3.5 portions of Rhizoma Cyperis of the Radix Linderae
1.5~2.5 parts of 1.5~2.5 parts of Pollen Tyjphae of 2.5~3.5 parts of Rhizoma Chuanxiongs of Radix Angelicae Sinensis
0.5~1.5 part of 1.5~2.5 parts of Oletum Trogopterori of 2.5~3.5 parts of Radix Paeoniae Rubra of Rhizoma Curcumae
0.5~1.5 part of 0.5~1.5 part of Rhizoma Corydalis of 1.5~2.5 portions of Fructus Gardeniaes of Semen Persicae
The weight proportion of each raw material of optimum formula of the present invention is:
2 parts of 2 parts of Cortex Moutans of 3 portions of Rhizoma Cyperis of the Radix Linderae
2 parts of 2 parts of Pollen Tyjphae of 3 parts of Rhizoma Chuanxiongs of Radix Angelicae Sinensis
1 part of 2 parts of Oletum Trogopterori of 3 parts of Radix Paeoniae Rubra of Rhizoma Curcumae
1 part of 1 part of Rhizoma Corydalis of 2 portions of Fructus Gardeniaes of Semen Persicae
Drug action mechanism among the present invention is as follows:
Radix Linderae property of medicine suffering, temperature.Return spleen, stomach, liver, kidney, urinary bladder channel.Have promoting the circulation of QI to relieve pain, the effect of warming kidney for dispelling cold.It is vexed to treat fullness in the chest and hypochondrium, and the gastral cavity abdomen swells and ache, headache, colic of cold type pain, dysmenorrhea and puerperal abdonimal pain, frequent micturition, the enuresis etc.(the 655th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Radix Angelicae Sinensis property of medicine is sweet, hot, bitter, temperature.Return liver, the heart, spleen channel.Having enriches blood invigorates blood circulation, menstruction regulating and pain relieving, the effect of moisturizing laxation.Can treat all cards of blood deficiency, menoxenia, amenorrhea, dysmenorrhea , mass in the abdomen knot is poly-, metrorrhagia, asthenia cold abdominalgia, flaccidity syndrome and arthralgia syndrome, numbness of the skin, the dryness of the intestine dyschezia, heavy after the bloody dysentery, ulcer sores, injury from falling down etc.(the 1210th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Rhizoma Curcumae nature and flavor hardship, suffering, temperature.Return liver, spleen channel.Have the circulation of qi promoting removing blood stasis with potent drugs, the removing food stagnancy pain relieving is changed poly-eliminating mass, the effect of antiearly pregnancy.Can treat that trusted subordinate's distending pain, lump in the abdomen, dyspepsia do not disappear, hepatosplenomegaly, abdominal pain due to blood stasis, amenorrhea due to stagnation of blood, cervical erosion, traumatic injury have a pain etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 995th page).
Semen Persicae property of medicine hardship, sweet, mild toxicity.GUIXIN, liver, large intestine channel.Has blood circulation promoting and blood stasis dispelling, the effect of loosening bowel to relieve constipation.Can treat dysmenorrhea, amenorrhea due to stagnation of blood, the stagnant stomachache of the stasis of blood in puerperal , mass in the abdomen caking, traumatic injury, swelling and pain due to blood stasis, lung abscess, acute appendicitis, dryness of the intestine constipation etc.(the 2542nd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Cortex Moutan property of medicine hardship, suffering are slightly cold.GUIXIN, liver, kidney channel.Has clearing away heat and cooling blood, the effect of promoting blood circulation to remove blood stasis.Can treat the epidemic febrile disease pathogenic heat attacking blood system in febrile diseases, send out speckle, tell nosebleed, the calentura later stage, hot Fu Yin divided heating, osteopyrexia and fever, and amenorrhea due to stagnation of blood, dysmenorrhea, mass in the abdomen, carbuncle sore tumefacting virus falls and pounces on the pain of injury, rheumatic arthralgia etc.(the 1578th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Rhizoma Chuanxiong property of medicine suffering, temperature.Return liver, gallbladder, pericardium channel.Has blood circulation promoting and blood stasis dispelling, activating QI to alleviate the depression, the effect of wind-expelling pain-stopping.Can treat menoxenia, the amenorrhea dysmenorrhea, the stagnant stomachache of the stasis of blood in puerperal , mass in the abdomen lump, pain in chest and hypochondrium, it is dizzy to have a headache, anemofrigid-damp arthralgia, traumatic injury, ulcer sores etc.(the 292nd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Radix Paeoniae Rubra property of medicine hardship is slightly cold.Return liver, spleen channel.Has clearing away heat and cooling blood, the effect of blood circulation promoting and blood stasis dispelling.Can treat maculae caused by violent heat pathogen, hematemesis and epistaxis, discharging fresh blood stool, conjunctival congestion and swelling pain, the carbuncle skin infection, amenorrhea, dysmenorrhea, the metrorrhagia and leukorrhagia stranguria with turbid discharge, the stasis of blood hypochondriac pain that stagnates, the hernia abdominal mass is gathered, injury from falling down etc.(the 1440th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Sweet, the little suffering of the Pollen Tyjphae property of medicine, flat.Return liver, the heart, spleen channel.Has hemostasis, blood stasis dispelling, diuretic effect.Can treat haematemesis, spitting of blood, epistaxis, dysentery is had blood in stool, metrorrhagia, traumatic hemorrhage, trusted subordinate's pain, amenorrhea stomachache, puerperal stasis of blood pain, dysmenorrhea, tumbling and swelling, blood strangury and dry pain, leukorrhagia, congenital deformity of the tongue, aphtha, ear, uncontrolled urination are itched etc.(the 3423rd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Rhizoma Cyperi property of medicine suffering, sweet, little hardship, flat.Return liver, tri-jiao channel.Has the resolving depression of regulating the flow of vital energy, regulating menstruation, antiabortive effect.Can treat distending pain over the hypochondrium, distending pain of the breast, hernia pain, menoxenia, gastral cavity abdomen feeling of fullness pain, belch acid regurgitation, vomiting and nausea, abdominal pain during menstruation, bleeding not during menses, frequent fetal movement etc.(the 2341st page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Oletum Trogopterori property of medicine hardship, sweet, temperature.Return liver, spleen channel.Has promoting blood circulation and stopping pain, removing stasis to stop bleeding, removing food stagnancy antidotal effect.Can treat all pains of trusted subordinate's vim and vigour, women's amenorrhea, the stasis of blood stagnated and suffered from abdominal pain metrostaxis, infantile malnutrition, snakes and scorpions centipete bite etc. puerperal.(the 517th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Rhizoma Corydalis property of medicine suffering, hardship, temperature.GUIXIN, liver, spleen channel.Has promoting blood circulation to remove blood stasis, the effect of promoting the circulation of QI to relieve pain.Can treat obstruction of qi in the chest and cardialgia, epigastric pain, lumbago, colicky, dysmenorrhea, amenorrhea , mass in the abdomen, the stasis of blood stagnated and suffered from abdominal pain traumatic injury etc. puerperal.(the 1261st page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Fructus Gardeniae property of medicine hardship, cold.GUIXIN, liver, lung, stomach, tri-jiao channel.Has the pathogenic fire purging relieving restlessness, clearing away heat-damp and promoting diuresis, the effect of removing pathogenic heat from blood and toxic substance from the body.It is vexed to treat calentura, the liver-fire conjunctival congestion, and headache, jaundice due to damp-heat, stranguria is spitted blood, epistaxis, dysentery, hematuria, aphtha of the mouth and tongue, sore swollen toxin is sprained and is swollen and ache etc.(the 2242nd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The present invention follows the principles of formulating prescriptions of the traditional Chinese medical science " monarch ", is monarch drug with the Radix Linderae, Radix Angelicae Sinensis and Rhizoma Curcumae, is ministerial drug with Cortex Moutan, Rhizoma Chuanxiong, Radix Paeoniae Rubra, Pollen Tyjphae, Rhizoma Cyperi and Semen Persicae; With Oletum Trogopterori, Rhizoma Corydalis and Fructus Gardeniae is adjuvant.All medicines are harmonious, and are total to the tool vital energy regualting and blood circulation-promoting, the effect of blood stasis dispelling gravidity assisting.The treatment endometriosis infertility has determined curative effect, has no side effect taking convenience, cheap characteristics.
Clinical drug of the present invention uses the result to show that following advantage is arranged:
1, the Chinese herbal medicine each component selected for use of the present invention meets the regulation of The Drug Administration Law of People's Republic of China, utilizes the comprehensive function treatment endometriosis infertility of the Chinese medicine of respectively distinguishing the flavor of, and is nontoxic to human body.Show that through the acute and chronic toxicity test of animal the animal of being tested does not see any toxic reaction, its main organs does not have tangible change yet, and safety of medicine is reliable.
2, rich in proteins in the medicine of the present invention, glucose, glucuronic acid, volatile oil, pectin, fructose, organic acid, lecithin, vitamin, aminoacid also contains various trace elements such as Saponin, plant sterol and calcium, is beneficial to absorption of human body, health invigorating.
3, the present invention not only can effectively treat endometriosis infertility, prevention to endometriosis infertility also has good effect, and the treatment endometriosis infertility has determined curative effect, has no side effect, taking convenience, cheap characteristics.
For showing the therapeutic effect of medicine of the present invention, as follows through clinical test results to the treatment endometriosis infertility; Treatment endometriosis infertility patient 16 examples.Take the embodiment decoction, each 1 bag, two to three times on the one, take half an hour ante cibum.One month is a course of treatment, take continuously three the course of treatment observe the curative effect.8 examples of fully recovering account for 50%, and 6 examples that take a turn for the better account for 37.5%, and more 2 examples do not account for 12.5%, and total effective rate reaches 87.5%.After three course of therapy, patient does not have any untoward reaction, and three big routine tests and hepatic and renal function detect no abnormal.
The specific embodiment
The embodiment decoction takes by weighing raw material by following weight:
2 parts of 2 parts of Cortex Moutans of 3 portions of Rhizoma Cyperis of the Radix Linderae
2 parts of 2 parts of Pollen Tyjphae of 3 parts of Rhizoma Chuanxiongs of Radix Angelicae Sinensis
1 part of 2 parts of Oletum Trogopterori of 3 parts of Radix Paeoniae Rubra of Rhizoma Curcumae
1 part of 1 part of Rhizoma Corydalis of 2 portions of Fructus Gardeniaes of Semen Persicae
Preparation method is to get above-mentioned raw materials to clean roguing, dries, and is ground into granule, soaks 1 hour, puts and decocts with water secondary in the multi-function extractor, adds up the water of 10 times of amounts of medical material for the first time, decocts 1.5~2 hours, gets decocting liquid, filters.Add up for the second time the water of 7 times of amounts of medical material, decocted 1~1.2 hour, get decocting liquid twice, filter, in the heat-sealing bag, 105 ℃ of high temperature sterilizes, packing is promptly.The decoction of the treatment endometriosis infertility that the present invention makes is that plastic packaging is packed, and every bag of 210ml is oral, one time one bag, every day two to three times.One month is a course of treatment.

Claims (3)

1, a kind of Chinese medicine preparation for the treatment of endometriosis infertility is characterized in that it is made by the following weight proportion raw material:
1.0~4 parts of 1.0~4 parts of Cortex Moutans of 1.5~6 portions of Rhizoma Cyperis of the Radix Linderae
1.0~4 parts of 1.0~4 parts of Pollen Tyjphae of 1.5~6 parts of Rhizoma Chuanxiongs of Radix Angelicae Sinensis
0.1~2 part of 1.0~4 parts of Oletum Trogopterori of 1.5~6 parts of Radix Paeoniae Rubra of Rhizoma Curcumae
0.1~2 part of 0.1~2 part of Rhizoma Corydalis of 1.0~4 portions of Fructus Gardeniaes of Semen Persicae
2, a kind of Chinese medicine preparation for the treatment of endometriosis infertility according to claim 1, wherein the weight proportion of each raw material is:
1.5~2.5 parts of 1.5~2.5 parts of Cortex Moutans of 2.5~3.5 portions of Rhizoma Cyperis of the Radix Linderae
1.5~2.5 parts of 1.5~2.5 parts of Pollen Tyjphae of 2.5~3.5 parts of Rhizoma Chuanxiongs of Radix Angelicae Sinensis
0.5~1.5 part of 1.5~2.5 parts of Oletum Trogopterori of 2.5~3.5 parts of Radix Paeoniae Rubra of Rhizoma Curcumae
0.5~1.5 part of 0.5~1.5 part of Rhizoma Corydalis of 1.5~2.5 portions of Fructus Gardeniaes of Semen Persicae
3, a kind of Chinese medicine preparation for the treatment of endometriosis infertility according to claim 1, wherein the weight proportion of each raw material is:
2 parts of 2 parts of Cortex Moutans of 3 portions of Rhizoma Cyperis of the Radix Linderae
2 parts of 2 parts of Pollen Tyjphae of 3 parts of Rhizoma Chuanxiongs of Radix Angelicae Sinensis
1 part of 2 parts of Oletum Trogopterori of 3 parts of Radix Paeoniae Rubra of Rhizoma Curcumae
1 part of 1 part of Rhizoma Corydalis of 2 portions of Fructus Gardeniaes of Semen Persicae
CNA2007100992308A 2007-05-16 2007-05-16 Traditional Chinese medicinal composition for treating endometriosis sterility Pending CN101053653A (en)

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CNA2007100992308A CN101053653A (en) 2007-05-16 2007-05-16 Traditional Chinese medicinal composition for treating endometriosis sterility

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105497393A (en) * 2014-10-11 2016-04-20 复旦大学附属妇产科医院 Traditional Chinese medicine compound preparation for treating endometriosis and preparation method thereof
CN109045162A (en) * 2018-10-25 2018-12-21 上海中医药大学附属岳阳中西医结合医院 Chinese medicine composition and its application for treating endometriosis
CN110876788A (en) * 2019-09-26 2020-03-13 遵义红花岗刘端方医院(普通合伙) Traditional Chinese medicine for promoting blood circulation and relieving pain and preparation method thereof

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105497393A (en) * 2014-10-11 2016-04-20 复旦大学附属妇产科医院 Traditional Chinese medicine compound preparation for treating endometriosis and preparation method thereof
CN109045162A (en) * 2018-10-25 2018-12-21 上海中医药大学附属岳阳中西医结合医院 Chinese medicine composition and its application for treating endometriosis
CN109045162B (en) * 2018-10-25 2021-05-04 上海中医药大学附属岳阳中西医结合医院 Traditional Chinese medicine composition for treating endometriosis and application thereof
CN110876788A (en) * 2019-09-26 2020-03-13 遵义红花岗刘端方医院(普通合伙) Traditional Chinese medicine for promoting blood circulation and relieving pain and preparation method thereof

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Open date: 20071017