CN100579594C - Medicinal liquid injection system - Google Patents
Medicinal liquid injection system Download PDFInfo
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- CN100579594C CN100579594C CN200580020301A CN200580020301A CN100579594C CN 100579594 C CN100579594 C CN 100579594C CN 200580020301 A CN200580020301 A CN 200580020301A CN 200580020301 A CN200580020301 A CN 200580020301A CN 100579594 C CN100579594 C CN 100579594C
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Abstract
A chemical liquid injection system with which a chemical liquid in a chemical liquid container can be directly injected into a patient without using a n intervening liquid syringe or the like. A trailing end of chemical liquid injection tube 120 that its leading end is connected to the patient is placed at a lower position within chemical liquid container 200. A leading end of liquid supply tube 110 is placed at a upper position within chemical liquid container 200 and a trailing end of liquid supply tube is connected to liquid container 300. Since liquid pressure-feeding mechanism 131 feeds the liquid in liquid container 300 into chemical liquid container 200 from liquid supply tube 110 with pressure, the chemical liquid is directly injected into the patient from chemical liquid container 200 through chemical liquid tube 120.
Description
Technical field
The present invention relates to the medicinal liquid of accommodating in the medical liquid container is injected into examinee's chemical liquid infusion system by liquid medicine injection apparatus.
Background technology
At present, as the fluoroscopic of the examinee being taken fluoroscopy images, comprise CT (Computed Tomography) scanning device, MRI (Magnetic Resonance Imaging) device, PET (Positron Emission Tomography) device, SPECT (Single Photon EmissionComputed Tomography) device, diagnostic ultrasound equipment, angiography device, MRA (MRAngio) device etc.
When using aforesaid device, inject medicinal liquids such as contrast agent sometimes to the examinee, and also practicability of the liquid medicine injection apparatus of automatically carrying out this injection.Aforesaid liquid medicine injection apparatus has injection head, and loading and unloading are equipped with medical fluid injector freely on this injection head.
Medical fluid injector is made of syringe member and piston component, and the syringe member forms drum.And then the syringe member is formed with through hole and end has opening at front end, so piston component is inserted in inside sliding freely from this opening.Usually, the through hole of the front end of syringe member forms outstanding duct portion, so in this duct portion binding the end that prolongs pipe is arranged.
This prolongation pipe is equipped with the injection pin integratedly at front end, links so should inject pin and examinee's blood vessel.Therefore, when using liquid medicine injection apparatus, will be filled with syringe member and examinee's binding of the medical fluid injector of medicinal liquid by prolonging pipe as mentioned above, and this medical fluid injector will be assemblied on the injection head of liquid medicine injection apparatus.
In common liquid medicine injection apparatus, on injection head, be formed with the recess with the syringe member corresponding shape of medical fluid injector, as long as can keep medical fluid injector at this recess filling syringe member.In addition, liquid medicine injection apparatus keeps piston component by piston drive mechanism, and is independent of the syringe member, and it is mobile by this piston drive mechanism piston component to be slided, thereby can inject medicinal liquid to the examinee from medical fluid injector.
In addition, aforesaid medical fluid injector has the prefill type and the type of recharging, for the prefill type, be under the state of in the syringe member, filling medicinal liquid and integral body being sealed, to go on the market by package, and for the type of recharging, be the medicinal liquid of in the syringe member, filling needs according to the user.Under this situation, the medical fluid injector of the type of recharging and jumbo medicine liquid tank link by prolonging pipe, pull out piston component by liquid medicine injection apparatus etc. from the syringe member of medical fluid injector, fill medicinal liquid from medicine liquid tank to medical fluid injector thus.
In addition,, inject the contrast agent of specified volume mostly earlier, inject the normal saline of specified volume then when the examinee who takes fluoroscopy images by fluoroscopic as mentioned above injects contrast agent.Realize the liquid medicine injection apparatus of this situation, have the structure that keeps being filled with the medical fluid injector of contrast agent side by side and be filled with the medical fluid injector of normal saline, at first drive the medical fluid injector of contrast agent, drive the medical fluid injector of normal saline then.In this liquid medicine injection apparatus, can only inject an amount of contrast agent to the shooting position, therefore can cut down the consumption of the contrast agent of high price, can also alleviate the burden on examinee's health.
In addition, in the RI (RadioIsotope) that has utilized described PET (Positron Emission Tomography) device or SPECT (Single Photon Emission Computed Tomography) device checks, radioisotopic medicinal liquid is made as contrast agent.But this contrast agent can be emitted deleterious lonizing radiation, so in order to prevent the operator by radiation exposure, and assembling is used to block the syringe cover of the tungsten system of lonizing radiation on this medical fluid injector.Therefore, RI checks the liquid medicine injection apparatus that is utilized, and has been assembled the syringe member of the medical fluid injector of syringe cover by the maintenance of injector drive mechanism.
In addition, in RI checks, can natural radioactive decay as the radiosiotope of contrast agent along with the process of time, thus need be before being about to be injected into the examinee medicinal liquid generating apparatus by special use generate contrast agent and be filled in the medical fluid injector.Under this situation,, make the sharp-pointed injection pin of medicinal liquid generating apparatus be punctured to the rubber cap of medical fluid injector at the duct portion assembling rubber cap of the front end of medical fluid injector.
Owing to fill radioisotopic contrast agent from the medicinal liquid generating apparatus to medical fluid injector in this state, thus from this medical fluid injector when the examinee injects contrast agent, the operator takes off rubber cap and links from medical fluid injector and prolongs pipe.In addition, aforesaid liquid medicine injection apparatus is past invention such as the applicant and the device (for example, with reference to patent documentation 1,2) applied for.
Patent documentation 1: the spy opens 2002-11096 number
Patent documentation 2: the spy opens 2002-102345 number
As mentioned above, inject medicinal liquid such as contrast agent to the examinee after, inject under the situation of normal saline, need to prepare respectively to be filled with the medical fluid injector of medicinal liquid and to be filled with the medical fluid injector of normal saline, and drive these medical fluid injectors respectively.But so the become structure of loaded down with trivial details while liquid medicine injection apparatus of operation also becomes complicated, also may produce to inject the such maloperation of medicinal liquid after for example injecting normal saline.
In addition, as mentioned above,, to the medical fluid injector of the type of recharging, fill medicinal liquid, inject medicinal liquid to the examinee from this medical fluid injector from medicine liquid tank in order to inject the medicinal liquid of medicine liquid tank to the examinee.But so operation is loaded down with trivial details, and medicinal liquid increases because of mobile and contaminated probability.
In addition, in above-mentioned RI checks, in order to prevent that the operator is by radiation exposure, and on medical fluid injector, be equipped with the syringe cover of tungsten system, but in the time will prolonging pipe and link with medical fluid injector, the operator need take off rubber cap from the medical fluid injector that is filled with radioisotopic contrast agent by manual work, and will prolong pipe by manual work and be assembled to herein, so will prolong pipe can be by radiation exposure with the banded operator of medical fluid injector.
Summary of the invention
The invention that the present invention realizes just in view of the above-mentioned problems, its purpose is, a kind of chemical liquid infusion system is provided, and is achieved as follows operation etc. simply with this: inject normal saline inject medicinal liquid such as contrast agent to the examinee after; Without the medical fluid injector of the type of recharging and inject the medicinal liquid of medicine liquid tank to the examinee; Even if radioisotopic contrast agent also can be made a bet into medicinal liquid in the not irradiated situation of operator, etc.
First chemical liquid infusion system of the present invention has first liquid container and liquid medicine injection apparatus, and this liquid medicine injection apparatus has first liquid injecting tube, second feed tube for liquid, second liquid container and the second liquid pressing mechanism.First liquid container contains first liquid as medicinal liquid, and liquid medicine injection apparatus injects this medicinal liquid to the examinee.The front end of first liquid injecting tube and examinee link and the terminal below, inside that is configured in first liquid container, and the front-end configuration of second feed tube for liquid is in the inner and upper of first liquid container.Second liquid container contains second liquid and links with the end of second feed tube for liquid, and the second liquid pressing mechanism is pressed into second liquid second liquid container from second feed tube for liquid to first liquid container.Therefore, by being pressed into second liquid, and inject first liquid via first liquid injecting tube to the examinee from this first liquid container to first liquid container.
In second chemical liquid infusion system of the present invention, the front-end configuration of second feed tube for liquid is in the inside of first liquid container, but because second liquid container contains second liquid of proportion less than first liquid, so by being pressed into this second liquid to first liquid container, and inject first liquid via first liquid injecting tube to the examinee from this first liquid container.
Have again, said various mechanisms form in the mode that realizes its function and get final product among the present invention, for example, can be achieved as follows function etc.: the specialized hardware of performance predetermined function, by computer program give the chemical liquid infusion system of predetermined function, the function of the regulation that realizes by chemical liquid infusion system by computer program, their combination etc.In addition, said various mechanisms must exist independently of one another among the present invention, also can be a plurality of mechanisms and form a member or certain mechanism and repeat etc. for the part of other mechanism or the part of certain mechanism and the part of other mechanism.
In chemical liquid infusion system of the present invention, be pressed into second liquid of second liquid container to first liquid container from second feed tube for liquid by the second liquid pressing mechanism, inject first liquid of this first liquid container thus to the examinee from first liquid injecting tube, thereby, be contrast agent and to make second liquid be normal saline for example by making first liquid, can carry out the action of after the examinee injects contrast agent, injecting normal saline simple and reliablely, can also under the situation of medical fluid injector of the type of recharging etc., directly inject medicinal liquid to the examinee from medical liquid container, therefore, even at medicinal liquid is under the situation of the contrast agent checked of RI, can prevent that also the operator is illuminated.
Description of drawings
Fig. 1 is the sketch map of the chemical liquid infusion system of expression embodiments of the present invention.
Fig. 2 is the sketch map of the chemical liquid infusion system of expression first variation.
Fig. 3 is the sketch map of the chemical liquid infusion system of expression second variation.
Fig. 4 is the sketch map of the chemical liquid infusion system of expression the 3rd variation.
Fig. 5 is the sketch map of the chemical liquid infusion system of expression the 4th variation.
Fig. 6 is the sketch map of the chemical liquid infusion system of expression the 5th variation.
Fig. 7 is the axonometric chart of the signal of expression needle-like deformation of members example;
Fig. 8 is the sketch map of the chemical liquid infusion system of expression the 6th variation;
Fig. 9 is the axonometric chart of the signal of expression needle-like deformation of members example.
100,400,500,600,700,800, the 900-liquid medicine injection apparatus among the figure:; 101-medicinal liquid maintaining body; 110,510-feed tube for liquid; 113-minute hand member; 120-medicinal liquid ascending pipe; 122-hour hand member; 131-liquid pressing mechanism; The 200-medical liquid container; The 201-container body; The 202-elastic component; The 300-liquid container; The 410-radome; 420-detection of end pick off; 430,513,514-check valve; 520-becomes the medical fluid injector of liquid pressing mechanism; 601-change-detection pick off; The 1000-chemical liquid infusion system; C-is as the contrast agent of medicinal liquid; W-is as the normal saline of liquid.
The specific embodiment
[formation of embodiment]
Below, with reference to accompanying drawing an embodiment of the invention are described.The chemical liquid infusion system 1000 of present embodiment is made of liquid medicine injection apparatus 100 and replacing medical liquid container 200 freely, in medical liquid container 200, contains the contrast agent C that PET uses as medicinal liquid.
More specifically, medical liquid container 200 is made of the container body 201 of the cylindric of glass and an end opening, and the opening of this container body 201 is airtight by the elastic component 202 that is made of silicone rubber etc.Because the contrast agent C that uses of PET has radioactivity, so be equipped with the jar 211 of the tungsten system that is used to block its lonizing radiation in the outside of container body 201.
Liquid medicine injection apparatus 100 is equipped with liquid container 300 independently with mode and the medical liquid container of changing freely 200, contains the normal saline W as liquid in this liquid container 300.This liquid container 300 is formed with the open pore 301 of minor diameter by two ends central authorities the cylindrical container main body 302 of glass constitutes, and is equipped with the lid 303 that is made of silicone rubber etc. in loading and unloading mode freely in this open pore 301.
In addition, contrast agent C compares enough big liquid by proportion with normal saline W and constitutes, in medical liquid container 200, only contain contrast agent C with the capacity that injects to the examinee, but in liquid container 300, contain the capacity identical with contrast agent C and inject that the capacity of giving the examinee adds and value more than the normal saline W of capacity.
The liquid medicine injection apparatus 100 of present embodiment has medicinal liquid maintaining body 101 and liquid maintaining body 102, keep medical liquid container 200 by medicinal liquid maintaining body 101 with the state that elastic component 202 is positioned at the below, and, keep liquid container 300 with the orientation in openings at two ends hole 301 state in the below by liquid maintaining body 102.
The liquid medicine injection apparatus 100 of present embodiment has feed tube for liquid 110 and medicinal liquid ascending pipe 120, and their feed tube for liquid 110 and medicinal liquid ascending pipe 120 have the tube body 111,121 that is made of softish silicone rubber etc. as major part.Feed tube for liquid 110 links liquid container 300 and medical liquid container 200, and medicinal liquid ascending pipe 120 links medical liquid container 200 and examinee's blood vessel (not shown).
More specifically, feed tube for liquid 110 is equipped with the adapter 112 of hard integratedly at the end of tube body 111, and this adapter 112 is assembled in the open pore 301 of liquid container 300 belows that kept in loading and unloading mode freely.In addition, feed tube for liquid 110 is equipped with the metal minute hand member 113 of sharp-pointed elongated tubular integratedly at the front end of tube body 111, and this minute hand member 113 pierces through the elastic component 202 of medical liquid container 200.
Medicinal liquid ascending pipe 120 is equipped with the piped metal hour hand member 122 of sharp-pointed weak point integratedly at the end of tube body 121, and this hour hand member 122 pierces through the elastic component 202 of medical liquid container 200.The front end of tube body 121 is equipped with conduit (not shown) such as (catheter) integratedly, and pierces through examinee's blood vessel and link.
In addition, the end of minute hand member 113 and hour hand member 122 remains one by clamping components 123, so minute hand member 113 and hour hand member 122 pierce through the elastic component 202 of medical liquid container 200 equally.Therefore, minute hand member 113 and hour hand member 122 from below pierce through under the state of elastic component 202 of the medical liquid container 200 that is kept, the front end of minute hand member 113 is positioned at the inner and upper of medical liquid container 200, and the front end of hour hand member 122 is positioned at the below, inside of medical liquid container 200.
Feed tube for liquid 110 its intermediary parts are inserted and are led in liquid pressing mechanism 131, and this liquid pressing mechanism 131 is pressed into from feed tube for liquid 110 the normal saline W in the liquid container 300 to medical liquid container 200.(not shown) such as roller pump mechanisms that the wriggling that liquid pressing mechanism 131 has wriggling refers to (peristaltic finger) mechanism or a plurality of roller member are rotated carries out force feed to it by pushing feed tube for liquid 110 successively from the outside under the state that does not contact normal saline W.
Near the endways part sequence interlock of medicinal liquid ascending pipe 120 has bubble to get rid of mechanism 132, bubble detecting sensor 133, injects blocking-up mechanism 134, this bubble detecting sensor 133 and injection blocking-up mechanism 134 are connected together with as the injection control unit 136 that injects controlling organization with liquid pressing mechanism 131.
Bubble is got rid of mechanism 132 and is formed by check valve etc., from get rid of bubble among the mobile contrast agent C medicinal liquid ascending pipe 120.Bubble detecting sensor 133 is formed by light-emitting component, photo detector and treatment circuit etc., detects the bubble of sneaking among the mobile contrast agent C in medicinal liquid ascending pipe 120.
Inject blocking-up mechanism 134 and constitute, block the mobile of contrast agent C by push medicinal liquid ascending pipe 120 from the outside by opening and closing freely switching mechanism etc.Injecting control unit 136 is made of the microcomputer that suitable computer program is installed etc., when detecting bubble by bubble detecting sensor 133, liquid pressing mechanism 131 is stopped, and by injecting blocking-up mechanism 134 blocking-up medicinal liquid ascending pipes 120.
[action of embodiment]
In aforesaid formation, when the examinee injects contrast agent C, at first, prepare to contain the medical liquid container 200 of this contrast agent C at the chemical liquid infusion system 1000 by present embodiment.As previously mentioned, because the contrast agent C that PET uses has radioactivity, so the container body 201 of this glass is configured in the inside of the jar 211 of tungsten system.
At present, in common medical liquid container 200, also be equipped with the shutter (not shown) of tungsten system, take off the elastic component 202 that this shutter will be exposed container body 201 in loading and unloading mode freely at the peristome of jar 211.In this state, after the minute hand/hour hand member 113,122 with the liquid supply/medicinal liquid ascending pipe 110,120 of fluid infusion apparatus 100 pierces through the elastic component 202 of medical liquid container 200, this medical liquid container 200 is remained on the liquid maintaining body 101.So the front end that the front end that becomes minute hand member 113 is positioned at the inner and upper of medical liquid container 200 and hour hand member 122 is positioned at the state of the below, inside of medical liquid container 200.
Then, prepare to contain the liquid container 300 that is equipped with lid 303 in normal saline W and the openings at two ends hole 301, the orientation in two ends in above state under, take off the lid 303 of this top and open open pore 301.In this state, after the open pore 301 of the top of the end of feed tube for liquid 110 and this liquid container 300 linked, under the state below this open pore 301 is positioned at liquid container 300 is remained on the liquid maintaining body 102.And, if take off lid 303, then become the state that normal saline W in the medical liquid container 300 freely is provided for feed tube for liquid 110 from the open pore 301 of the top that is arranged in this liquid container 300.
Under aforesaid state, for example when injecting control unit 136 input operations " warming up execution ", then this injection control unit 136 is opened and is injected blocking-up mechanism 134 driving liquid pressing mechanisms 131 to the stipulated time.So, supply with the normal saline W of specified volume to medical liquid container 200 via feed tube for liquid 110 from liquid container 300 by this liquid pressing mechanism 131, so, from the contrast agent C of airtight medical liquid container 200 to 120 injections of medicinal liquid ascending pipe and filling specified volume.
In the inside of like this liquid supplys/medicinal liquid ascending pipe 110,120 by normal saline W and contrast agent C fills and behind the deaeration, with the front end of this medicinal liquid ascending pipe 120 and examinee's blood vessel binding.In this state, for example when injecting control unit 136 input operations " injecting action carries out ", then this injection control unit 136 still drives liquid pressing mechanism 131 to the stipulated time.
So, supply with the normal saline W of specified volumes via feed tube for liquid 110 to medical liquid container 200 from liquid container 300 by this liquid pressing mechanism 131, inject contrast agent C via medicinal liquid ascending pipe 120 to the examinee from this medical liquid container 200.At this moment, because the proportion of normal saline W is less than contrast agent C, so, form contrast agent C and be positioned at the state that below and normal saline W are positioned at the top in the inside of medical liquid container 200.
In addition, in the liquid medicine injection apparatus 100 of present embodiment, even after the examinee injects whole contrast agent C, also can drive liquid pressing mechanism 131, so inject to the examinee from the normal saline W of liquid container 300 to medical liquid container 200 force feeds to the stipulated time from medical liquid container 200.
At this owing to push contrast agent C from behind, so contrast agent C arrives the shooting position as the captured examinee of the PET device (not shown) of fluoroscopic by normal saline W.So arrived the contrast agent C at shooting position, compared, absorbed more well by so-called " cancerous cell ", so can be by take the absorbing state of this contrast agent C as the PET device of fluoroscopic with " normal cell ".
In addition, as mentioned above, when the examinee injected contrast agent C or normal saline W, the bubble of sneaking into was wherein got rid of by bubble eliminating mechanism 132 by medicinal liquid ascending pipe 120.When this bubble was not excluded, this bubble was detected by bubble detecting sensor 133, thus according to this detection, inject control unit 136 liquid pressing mechanism 131 is stopped, and by injecting blocking-up mechanism 134 blocking-up medicinal liquid ascending pipes 120.
[effect of embodiment]
In the chemical liquid infusion system 1000 of present embodiment, by liquid pressing mechanism 131 the normal saline W in the liquid container 300 is pressed into the medical liquid container 200 from feed tube for liquid 110, thus the contrast agent C in this medical liquid container 200 is injected from medicinal liquid ascending pipe 120 and give the examinee, so can under the situation of the medical fluid injector of the type of recharging etc., directly inject contrast agent C to the examinee from medical liquid container 200.
Therefore, the operator needn't fill contrast agent C or operate this medical fluid injector to medical fluid injector from medical liquid container 200, even thereby have under radioactive situation at contrast agent C, can prevent well that also the operator is illuminated, can also prevent the pollution of contrast agent C etc. simple and infalliblely.
Especially, owing to the medium that contrast agent C is pressurizeed is made of normal saline W, so even can pressurize to contrast agent C by injecting the also in-problem medium of examinee.And, because the proportion of contrast agent C is compared enough big with normal saline W, the front-end configuration of feed tube for liquid 110 is in the inner and upper of medical liquid container 200, and the end of medicinal liquid ascending pipe 110 is configured in the below, inside of medical liquid container 200, so can at first only inject contrast agent C, can also carry out the action of injecting normal saline W afterwards simply to the examinee.
And in the chemical liquid infusion system 1000 of present embodiment, the opening of medical liquid container 200 is airtight by elastic component 202, and the minute hand of liquid supply/medicinal liquid ascending pipe 110,120/hour hand member 113,122 pierces through elastic component 202.Therefore, liquid can be supplied with/medicinal liquid ascending pipe 110,120 is attached to medical liquid container 200 simply, thereby can prevents more well that the operator is illuminated.
In addition, the minute hand of liquid supply/medicinal liquid ascending pipe 110,120/hour hand member 113,122 remains one by clamping components 123, so liquid can be supplied with/medicinal liquid ascending pipe 110,120 is attached to more simply on the medical liquid container 200, and the minute hand/front end of hour hand member 113,122 can be configured to the appropriate position of medical liquid container 200 inside simple and infalliblely.
In addition, by medicinal liquid ascending pipe 120 when the examinee injects contrast agent C or normal saline W, sneak into wherein bubble and got rid of mechanism 132 by bubble and get rid of, so can prevent to inject bubble to the examinee.Have again, detect the bubble that is not excluded by bubble detecting sensor 133, inject control unit 136 and liquid pressing mechanism 131 is stopped by force according to this detection, and by injecting blocking-up mechanism 134 blocking-up medicinal liquid ascending pipes 120, so can prevent to inject bubble to the examinee infalliblely.
[variation of embodiment]
The present invention is not limited to present embodiment, is permitted to carry out various distortion at the range content that does not break away from its aim.For example, illustration is as follows in the above-mentioned embodiment: in order to inject under the situation of not fine mixing contrast agent C and normal saline W, be equipped with hour hand member 122 and be equipped with minute hand member 113 at the end of medicinal liquid ascending pipe 120 at the front end of feed tube for liquid 110, make the end of medicinal liquid ascending pipe 120 be positioned at the below, inside of medical liquid container 200 thus, and make the front end of feed tube for liquid 110 be positioned at inner and upper.
But, liquid medicine injection apparatus 700 is such as illustrated in Figure 5, can also be by needle-like member 141,142 in the end assembling equal length of the front end of feed tube for liquid 110 and medicinal liquid ascending pipe 120, and make the terminal both sides of the front end of feed tube for liquid 110 and medicinal liquid ascending pipe 120 all be positioned at the below, inside etc. of medical liquid container 200.
In this case, in being injected into examinee's medicinal liquid, increase from the probability of just sneaking into liquid at first, but for example, if the proportion of medicinal liquid is compared enough big with the proportion of liquid, or needle-like member 141,142 fully deviates from the horizontal direction, and liquid or possible then reinjects after the examinee injects medicinal liquid.
In addition, as illustrated in Figure 6 shown in the liquid medicine injection apparatus 800, the needle-like member 141,142 of the equal length of feed tube for liquid 110 and medicinal liquid ascending pipe 120 can also be formed a needle-like member 143.In this case, except shown in Fig. 7 (a), beyond two columnar needle-like members 141,142 arranged side by side joints, also can shown in Fig. 7 (b), form two cavities in advance side by side in the inside of a columnar needle-like member 143 as needle-like member 141,142.
As in the above-mentioned needle-like member 143, can omit the clamping components 123 that one keeps two needle-like members 141,142, the elastic component 202 that only a needle-like member 143 is pierced through medical liquid container 200 gets final product, so can improve its operation.
Have again, shown in the liquid medicine injection apparatus 900, hour hand member 122 and minute hand member 113 can also be formed a needle-like member 145 certainly as illustrated in Figure 8.In this case, as shown in Figure 9,, can also form two cavities side by side in the inside of a columnar needle-like member 145 as hour hand member 122 and minute hand member 113 except with columnar hour hand member 122 and minute hand member 113 arranged side by side the joints.
In addition, in the above-mentioned embodiment illustration radioactive contrast agent C of using by PET of medicinal liquid situation about constituting, inject but chemical liquid infusion system 1000 can be used for various medicinal liquids.In addition, in the above-mentioned embodiment illustration jar 211 of medical liquid container 200 be tungsten system, but it also can be lead system etc.
In addition, in the above-mentioned embodiment illustration following situation: for the end that makes medicinal liquid ascending pipe 120 is positioned at the inside below of medical liquid container 200 and makes the front end of feed tube for liquid 110 be positioned at the inner and upper of medical liquid container 200, and the minute hand member 113 of the hour hand member 122 of medicinal liquid ascending pipe 120 and feed tube for liquid 110 is pierced through the elastic component 202 of medical liquid container 200, keep medical liquid container 200 under the state below this elastic component 202 is positioned at.
But, also can be in advance form the minute hand member and form minute hand member (not shown) at the front end of feed tube for liquid at the end of medicinal liquid ascending pipe, the mode that is positioned at the top with elastic component 202 keeps medical liquid container 200, and the minute hand member of medicinal liquid ascending pipe and the minute hand member of feed tube for liquid are pierced through this elastic component 202.
In addition, in the above-mentioned embodiment illustration following situation: for medicinal liquid ascending pipe 120 and feed tube for liquid 110 are attached to the medical liquid container 200 that existing P ET uses simply, and the minute hand member 113 of the hour hand member 122 of medicinal liquid ascending pipe 120 and feed tube for liquid 110 is pierced through the elastic component 202 of medical liquid container 200.But, also can in advance the hour hand member 122 of medicinal liquid ascending pipe 120 and the minute hand member 113 of feed tube for liquid 110 be attached to special-purpose elastic component (not shown), and the elastic component 202 of this elastic component and medical liquid container 200 is changed.
More specifically, open and close the opening of airtight medical liquid container freely by airtight member in advance,, and form the long tube member of elongated tubular at the front end of feed tube for liquid at the piped short tube member of the terminal integrally formed weak point of medicinal liquid ascending pipe.In addition, form with the guaranteeing of opening of the loading and unloading airtight medical liquid container of mode freely and hold member, guarantee at this and hold integrally formed short tube member and long tube member (not shown) on the member.
In this case, guarantee and hold member that the state that is positioned at the below with opening keeps this medical liquid container if open the airtight member assembling of medical liquid container, then becoming can be by the state that injects contrast agent C to the examinee that is pressed into of normal saline W.Have, in this structure, the airtight member that need open medical liquid container assembles to be guaranteed and holds member again, so this operation is also more loaded down with trivial details than piercing through of hour hand/minute hand member 122,113, but the seal of the medical liquid container under can the pressurize effect.
Have again, certainly, keep aforesaid medical liquid container if be positioned at the state of top with opening, then form short piped short tube member comparatively suitable (not shown) at the long tube member of the terminal integrally formed elongated tubular of medicinal liquid ascending pipe and at the front end of feed tube for liquid.
In addition, illustration in the above-mentioned embodiment: liquid supply/medicinal liquid ascending pipe 110,120 is attached to after medicinal liquid/liquid container 200,300, contrast agent C or normal saline W and deaeration are filled in inside at this liquid supply/medicinal liquid ascending pipe 110,120, but for example also can before being attached to medicinal liquid/liquid container 200,300, be pre-charged with normal saline W etc. in the inside of liquid supply/medicinal liquid ascending pipe 110,120.
In addition, in the above-mentioned embodiment illustration structure of having only the container body 201 of medical liquid container 200 to be shielded by jar 211, but also liquid medicine injection apparatus 400 is such as illustrated in Figure 2, the radome 410 of blocking-up lonizing radiation is integrally formed with medicinal liquid maintaining body 101, by these radome 410 airtight parts that are communicated with from the end of medicinal liquid ascending pipe 120.
In this case, if have the medical liquid container 200 of medicinal liquid ascending pipe 120 to remain on the medicinal liquid maintaining body 101 binding, then medicinal liquid ascending pipe 120 has only and links necessary fore-end with the examinee and expose from radome 410, so the major part of lonizing radiation that can be by radome 410 blocking-up contrast agent C radiation.
In addition, illustration in the above-mentioned embodiment: if detect the bubble that is blended among the contrast agent C by bubble detecting sensor 133, liquid pressing mechanism 131 is stopped by force, and by injecting blocking-up mechanism 134 blocking-up medicinal liquid ascending pipes 120, but also liquid medicine injection apparatus 400 is such as illustrated in Figure 2, assembling is used to detect the detection of end pick off 420 that the supply of normal saline W finishes on feed tube for liquid 110, when detecting the supply end by this detection of end pick off 420, the stop liquid pressing mechanism 131 by force, or by special-purpose supply blocking-up mechanism (not shown) blocking-up feed tube for liquid 110.
In addition, liquid medicine injection apparatus 600 is such as illustrated in Figure 4, can on medicinal liquid ascending pipe 120, assemble the change-detection pick off 601 that is used for becoming normal saline W in advance according to the contrast agent C that has or not detection of radioactive of lonizing radiation, when detecting variation in this medicinal liquid ascending pipe 120, the stop liquid pressing mechanism 131 by force.
In the liquid medicine injection apparatus 100 of above-mentioned embodiment,, be difficult to correctly confirm whether the contrast agent C in the medical liquid container 200 all injects to the examinee owing to inject to the examinee by the contrast agent C in the normal saline W pushing medical liquid container 200.But, as mentioned above, mobile contrast agent C becomes normal saline W in medicinal liquid ascending pipe 120 if detect by change-detection pick off 601, can confirm simple and infalliblely then whether the contrast agent C in the medical liquid container 200 all injects to the examinee, thus can be with the time stop liquid pressing mechanism 131 of expectation.
Have again, can also when detect by change-detection pick off 601 that mobile contrast agent C becomes normal saline W in medicinal liquid ascending pipe 120, continue force feed normal saline W it is stopped.In this case, owing to after contrast agent C, inject the normal saline W of specified volume to the examinee, so can make contrast agent C arrive examinee's shooting position definitely by normal saline W.
In addition, as mentioned above, after mobile contrast agent C changes in medicinal liquid ascending pipe 120, continue force feed normal saline W in normal saline W until reaching specified volume, when making contrast agent C arrive the shooting position thus, the capacity of normal saline W that continues this force feed is different because of the shooting position.
Therefore, can also mechanism as described below be set at the injection control unit 136 of liquid medicine injection apparatus 600, promptly constitute and the position input mechanism at the shooting position of data inputs PET device by keyboard or touch panel etc., or by formation such as HDD (Hard Disc Drive) or flash memory and each shooting position is carried out the capacity storage mechanism of data storage of the capacity of liquid, or by logic circuit or microcomputer etc. constitutes and data are read corresponding capacity when the data input shooting position capacity sense station.In this case, if operator's data are imported examinee's shooting position, then continue the capacity of the force feed of normal saline W, so can correctly inject contrast agent C to various shootings position corresponding to this shooting position control.
In addition, as mentioned above,, after the contrast agent C that passes through injection is by the stipulated time that cell absorbed, begin image pickup injecting to the examinee under radioactive contrast agent C and the situation by shooting fluoroscopy images such as PET device.Therefore, also can on liquid medicine injection apparatus, form following mechanism: promptly, the detection of end mechanism that the injection of contrast agent detection C finishes, detecting (not shown) such as data transport mechanisms of injecting the time detecting mechanism detected when finishing through the stipulated time, detected effluxion data being sent to PET device by microcomputer or I/F unit etc.
In this case, liquid medicine injection apparatus will send these effluxion data to PET device through the stipulated time after the injection that finishes contrast agent C, so, begin image pickup if data receive the PET device of this effluxion, then can under the state that contrast agent C is suitably absorbed by cell, automatically perform image pickup.Have, also can be liquid medicine injection apparatus finish immediate data with the injection of contrast agent C conveys to PET device again, and this PET device detects through beginning image pickup after the stipulated time.
In addition, illustration in the above-mentioned embodiment: utilize liquid pressing mechanism 131 with normal saline W from liquid container 300 via feed tube for liquid 110 force feeds to medical liquid container 200, thus from this medical liquid container 200 via the situation of medicinal liquid ascending pipe 120 to examinee's force feed contrast agent C.But, only under the effect of the force feed of this liquid pressing mechanism 131, there are the probability of adverse current in normal saline W or contrast agent C, in this case, for example, liquid medicine injection apparatus 400 is such as illustrated in Figure 2, can insert the check valve 430 that the flow direction of normal saline W is limited in a direction in feed tube for liquid 110, or inserts the check valve (not shown) that the flow direction of contrast agent C is limited in a direction in medicinal liquid ascending pipe 120.
In addition, illustration in the above-mentioned embodiment: liquid pressing mechanism 131 has wriggling and refers to mechanism or rotary pump mechanism etc., by from the outside to pushing the situation that waits force feed normal saline W successively with liquid container 300 banded feed tube for liquid 110.But, also can be liquid pressing mechanism (not shown) as follows etc., that is, and by in the syringe member of the medical fluid injector that is filled with normal saline W, being pressed into piston component, thus to being pressed into normal saline W with the banded feed tube for liquid of this medical fluid injector.
More specifically, in the illustrated liquid medicine injection apparatus 500 of Fig. 3, two ends at the feed tube for liquid 510 of bifurcation structure, linking respectively has liquid container 300 and as the medical fluid injector 520 of liquid pressing mechanism, in the part 511 that is communicated to medical fluid injector 520 from liquid container 300 of this feed tube for liquid 510 be communicated to from medical fluid injector 520 on the part 512 of medical liquid container 200, be inserted with the first/the second check valve 513,514 respectively.
In this liquid medicine injection apparatus 500, normal saline W's in the feed tube for liquid 510 flows, be restricted to from liquid container 300 to medical fluid injector 520 direction by first check valve 513, and be restricted to from medical fluid injector 520 to medical liquid container 200 direction by second check valve 514.
In addition, medical fluid injector 520 is to be inserted with piston component 522 in the mode that slides freely in syringe member 521, makes syringe member 521 draw and discharge normal saline W by piston component 522 being slided move.Therefore, in the illustrated liquid medicine injection apparatus 500 of Fig. 3, by carrying out the absorption and the discharge of medical fluid injector 520 repeatedly, with normal saline W from liquid container 300 via medical fluid injector 520 force feeds to medical liquid container 200.
Claims (31)
1. chemical liquid infusion system has to contain as first liquid container of first liquid of medicinal liquid with to the examinee and injects the liquid medicine injection apparatus of described first liquid, wherein,
Described liquid medicine injection apparatus has:
First liquid injecting tube, its front end and described examinee link and the terminal inside that is configured in described first liquid container;
Second feed tube for liquid, its front-end configuration is in the inside of described first liquid container;
Second liquid container, it contains second liquid different with described first liquid and links with the end of described second feed tube for liquid; With
The second liquid pressing mechanism, it is pressed into described second liquid described second liquid container from described second feed tube for liquid to described first liquid container.
2. chemical liquid infusion system according to claim 1, wherein,
The described end of described first liquid injecting tube is configured in the below, inside of described first liquid container,
The described front-end configuration of described second feed tube for liquid is in the inner and upper of described first liquid container.
3. chemical liquid infusion system according to claim 2, wherein,
Described first liquid container has the elastic component of the opening of the container body of a part of opening and airtight this container body,
Described liquid medicine injection apparatus has the state that is positioned at the below with described elastic component and keeps the first liquid maintaining body of described first liquid container,
Described first liquid injecting tube is formed with the piped hour hand member of the weak point that pierces through described elastic component endways,
Described second feed tube for liquid is formed with the minute hand member of the elongated tubular that pierces through described elastic component at front end.
4. chemical liquid infusion system according to claim 2, wherein,
Described first liquid container has the elastic component of the opening of the container body of a part of opening and airtight this container body,
Described liquid medicine injection apparatus has the state that is positioned at the top with described elastic component and keeps the first liquid maintaining body of described first liquid container,
Described first liquid injecting tube is formed with the minute hand member of the elongated tubular that pierces through described elastic component endways,
Described second feed tube for liquid is formed with the piped hour hand member of the weak point that pierces through described elastic component at front end.
5. chemical liquid infusion system according to claim 3, wherein,
Described hour hand member and described minute hand member are integrally formed.
6. chemical liquid infusion system according to claim 2, wherein,
Described first liquid container has the container body of a part of opening and with the airtight member of the opening that opens and closes airtight this container body of mode freely,
Described first liquid injecting tube is formed with short piped short tube member endways,
Described second feed tube for liquid is formed with the long tube member of elongated tubular at front end,
Described liquid medicine injection apparatus has: with described short tube member with described long tube member is integrally formed and hold member and keep the first liquid maintaining body of described first liquid container with the state that described opening is positioned at the below with guaranteeing of the opening of loading and unloading airtight described first liquid container of mode freely.
7. chemical liquid infusion system according to claim 2, wherein,
Described first liquid container has the container body of a part of opening and with the airtight member of the opening that opens and closes airtight this container body of mode freely,
Described first liquid injecting tube is formed with the long tube member of elongated tubular endways,
Described second feed tube for liquid is formed with short piped short tube member at front end,
Described liquid medicine injection apparatus has: with described short tube member with described long tube member is integrally formed and hold member and keep the first liquid maintaining body of described first liquid container with the state that described opening is positioned at the top with guaranteeing of the opening of loading and unloading airtight described first liquid container of mode freely.
8. chemical liquid infusion system according to claim 3, wherein,
Described first liquid container has to accommodate and has radioactive contrast agent as the container body of described first liquid with block the jar of the lonizing radiation of described contrast agent,
Described liquid medicine injection apparatus has an airtight at least part that is communicated with from the described end of described first liquid injecting tube to block the radome of described lonizing radiation, and this radome and the described first liquid maintaining body are integrally formed.
9. chemical liquid infusion system according to claim 2, wherein,
Described second liquid container contains described second liquid of proportion less than described first liquid.
10. chemical liquid infusion system according to claim 1, wherein,
The described end of described first liquid injecting tube is configured in the below, inside of described first liquid container,
Described second liquid container contains described second liquid of proportion less than described first liquid.
11. chemical liquid infusion system according to claim 9, wherein,
Described first liquid container contains contrast agent as described first liquid,
Described second liquid container contains normal saline as described second liquid.
12. chemical liquid infusion system according to claim 2, wherein,
Described liquid medicine injection apparatus also has: the bubble detecting sensor, and it detects the bubble of sneaking in mobile described first liquid in described first liquid injecting tube; With the injection controlling organization, it stops the described second liquid pressing mechanism by force when described bubble is detected.
13. chemical liquid infusion system according to claim 2, wherein,
Described liquid medicine injection apparatus also has: the bubble detecting sensor, and it detects the bubble of sneaking in mobile described first liquid in described first liquid injecting tube; With inject blocking-up mechanism, it blocks flowing of described first liquid in described first liquid injecting tube when described bubble is detected.
14. chemical liquid infusion system according to claim 2, wherein,
Described liquid medicine injection apparatus also has bubble and gets rid of mechanism, and it is from getting rid of bubble in mobile described first liquid described first liquid injecting tube.
15. chemical liquid infusion system according to claim 2, wherein,
Described liquid medicine injection apparatus also has: the detection of end pick off, and it detects from described second liquid container and finishes via the supply of the described second feed tube for liquid force feed to described second liquid of described first liquid container; With the injection controlling organization, it stops the described second liquid pressing mechanism by force when described end is detected.
16. chemical liquid infusion system according to claim 2, wherein,
Described liquid medicine injection apparatus also has: the detection of end pick off, and it detects from described second liquid container and finishes via the supply of the described second feed tube for liquid force feed to described second liquid of described first liquid container; With supply with blocking-up mechanism, it blocks flowing of described second liquid in described second feed tube for liquid when described end is detected.
17. chemical liquid infusion system according to claim 2, wherein,
Also have: the change-detection pick off, it detects from described first liquid container and becomes described second liquid via the described first liquid injecting tube force feed to described examinee's described first liquid; With inject controlling organization, it moves control corresponding to the detection of described variation to the described second liquid pressing mechanism.
18. chemical liquid infusion system according to claim 17, wherein,
Described first liquid container contains has radioactive contrast agent as described first liquid,
Described change-detection pick off detects described first liquid according to having or not of lonizing radiation and becomes described second liquid.
19. chemical liquid infusion system according to claim 17, wherein,
Described injection controlling organization stops the described second liquid pressing mechanism when described variation is detected by force behind described second liquid of force feed specified volume.
20. chemical liquid infusion system according to claim 19, wherein,
Also have the fluoroscopic of taking fluoroscopy images from the position of described first liquid of described examinee's injection,
Described liquid medicine injection apparatus also has: position input mechanism, its data are imported the shooting position of described fluoroscopic; Capacity storage mechanism, it stores the capacity of described second liquid to each described image pickup part bit data; With the capacity sense station, data were read corresponding described capacity when it imported described shooting position in data,
Described injection controlling organization stops the described second liquid pressing mechanism when described variation is detected by force behind described second liquid of the described capacity that the force feed data are read.
21. chemical liquid infusion system according to claim 2, wherein,
Also have the fluoroscopic of taking fluoroscopy images from the position of described first liquid of described examinee's injection,
Described liquid medicine injection apparatus also has: detection of end mechanism, and its injection that detects described first liquid finishes; And data transport mechanisms, it sends detected described injection end data to described fluoroscopic,
Described fluoroscopic has: the image pickup mechanism of taking described fluoroscopy images; Data receive the data receiver structure that described injection finishes; Receive the elapsed time testing agency of detecting the stipulated time when described injection finishes in data; With at the shooting controlling organization that makes when the stipulated time described image pickup mechanism begin to make a video recording.
22. chemical liquid infusion system according to claim 2, wherein,
Also have the fluoroscopic of taking fluoroscopy images from the position of described first liquid of described examinee's injection,
Described liquid medicine injection apparatus also has: detection of end mechanism, and its injection that detects described first liquid finishes; Time detecting mechanism, it detects the process of stipulated time when described injection finishes to be detected; And data transport mechanisms, it sends detected effluxion data to described fluoroscopic,
Described fluoroscopic has: the image pickup mechanism of taking described fluoroscopy images; Data receive the data receiver structure of described effluxion; The shooting controlling organization that when data receive described effluxion, makes described image pickup mechanism begin to make a video recording.
23. chemical liquid infusion system according to claim 2, wherein,
In described second feed tube for liquid, be inserted with flow direction restriction check valve in one direction with described second liquid.
24. chemical liquid infusion system according to claim 2, wherein,
In described first liquid injecting tube, be inserted with flow direction restriction check valve in one direction with described first liquid.
25. chemical liquid infusion system according to claim 2, wherein,
Described second liquid container is changed freely.
26. a liquid medicine injection apparatus is the liquid medicine injection apparatus of the described chemical liquid infusion system of claim 1.
27. liquid medicine injection apparatus according to claim 26, wherein,
The described end of described first liquid injecting tube is configured in the below, inside of described first liquid container,
The described front-end configuration of described second feed tube for liquid is in the inner and upper of described first liquid container.
28. liquid medicine injection apparatus according to claim 26, wherein,
The described end of described first liquid injecting tube is configured in the below, inside of described first liquid container,
Described second liquid container contains described second liquid of proportion less than described first liquid.
29. liquid medicine injection apparatus according to claim 27 wherein, has:
The position input mechanism, the shooting position of the fluoroscopic of fluoroscopy images is taken in its data input from the position of described first liquid of described examinee's injection;
Capacity storage mechanism, it stores the capacity of described second liquid to each described image pickup part bit data;
The capacity sense station, data were read corresponding described capacity when it imported described shooting position in data;
The change-detection pick off, it detects contrast agent and becomes normal saline, and described contrast agent is given examinee through the medicinal liquid ascending pipe by force feed from medical liquid container; With
Inject controlling organization, when it is detected in described variation, the described second liquid pressing mechanism is stopped by force behind described second liquid of the described capacity that the force feed data are read.
30. liquid medicine injection apparatus according to claim 29 wherein, has:
Detection of end mechanism, its injection that detects described first liquid finishes; With
Data transport mechanisms, it sends detected described injection end data to described fluoroscopic.
31. liquid medicine injection apparatus according to claim 29 wherein, has:
Detection of end mechanism, its injection that detects described first liquid finishes;
Time detecting mechanism, it detects the process of stipulated time when described injection finishes to be detected; With
Data transport mechanisms, it sends detected effluxion data to described fluoroscopic.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2004182475 | 2004-06-21 | ||
| JP182475/2004 | 2004-06-21 | ||
| JP327480/2004 | 2004-11-11 |
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| Publication Number | Publication Date |
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| CN1968724A CN1968724A (en) | 2007-05-23 |
| CN100579594C true CN100579594C (en) | 2010-01-13 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN200580020301A Expired - Fee Related CN100579594C (en) | 2004-06-21 | 2005-06-06 | Medicinal liquid injection system |
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| CN (1) | CN100579594C (en) |
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| JP5468082B2 (en) * | 2009-09-17 | 2014-04-09 | パナソニック株式会社 | Chemical solution injection apparatus and chemical solution injection method |
| CN107997791A (en) * | 2017-12-15 | 2018-05-08 | 赵继国 | A kind of cardiovascular devices |
| WO2019169530A1 (en) * | 2018-03-05 | 2019-09-12 | 深圳柔宇显示技术有限公司 | Conveying device and conveying method therefor |
| CN113509246B (en) * | 2021-07-19 | 2022-04-15 | 四川大学华西医院 | Blood vessel intervention device with radiation protection function |
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