CN100562324C - A kind of medicine for the treatment of burn, scalding and preparation method thereof - Google Patents
A kind of medicine for the treatment of burn, scalding and preparation method thereof Download PDFInfo
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- CN100562324C CN100562324C CNB2006101282087A CN200610128208A CN100562324C CN 100562324 C CN100562324 C CN 100562324C CN B2006101282087 A CNB2006101282087 A CN B2006101282087A CN 200610128208 A CN200610128208 A CN 200610128208A CN 100562324 C CN100562324 C CN 100562324C
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- oleum sesami
- periostracum serpentis
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Abstract
A kind of medicine for the treatment of burn, scalding is made by following materials based on weight: 200-500 part Oleum sesami, 5-30 part Cortex sophorae, 5-20 part Periostracum Serpentis.Its preparation method is: get parts by weight 200-500 part Oleum sesami, 5-30 part Cortex sophorae, 5-20 part Periostracum Serpentis, Cortex sophorae, Periostracum Serpentis are fused into the Oleum sesami mixing, fried concentrating forms.Perhaps Cortex sophorae, Periostracum Serpentis are worn into fine powder and fuse into the Oleum sesami mixing, fried concentrating forms.Fried concentrated condition is 250-350 ℃ and boiled 1-2 hour.Medication effect of the present invention is good.
Description
Technical field
The invention belongs to the medicinal preparation technical field, particularly a kind of medicine for the treatment of burn, scalding and preparation method thereof.
Background technology
Burn and scald are the acute sick and wounded of serious harm human life health.Burn comprises physics burn and chemical burn, patient's life security is directly worked the mischief treatment and difficult treatment; Scald is that the liquid, solid, the gaseous matter that are higher than human body temperature are burnt to human body skin top layer and deep layer.Burn and scald mostly occur in human body skin top layer and deep tissues, can divide I, II, III degree by burning the degree of depth.Burn causes very easily that top layer bacterial infection, body fluid exosmose, pain, burn and scald continuous tissue necrosis and leave over difficult problems such as cicatrix.Burn, the therapeutic modality of scalding be roughly sterilization, pain relieving, cleaning wound surface, protect from infection etc., normal silver sulfadiazine bandaging strapping and the moist expose burn ointment exposure method of adopting treated, coating ointment and antibiotic antiinflammatory, additional body fluid reach to be taked to rescue to deep burn person, in case the measure of internal organs depletion.But silver sulfadiazine has stimulation pain, anaphylaxis to skin, and liver, kidney are had infringement, and this medicine is the infant of renal insufficiency and women breast-feeding their children's forbidding medicine, and the gerontal patient has the increase phenomenon to this medicine generation untoward reaction probability.Need clear up wound surface repeatedly after this medicine coating, separate slough, increase the probability that infects.Though moist expose burn ointment has adopted Chinese traditional Chinese prescription, present China and other countries to apply: before medication, need burn wound is carried out the cleaning of ploughing and weeding formula; Though exposure method is carried out in the coating back, medicine is a paste, can not must be removed the medicine of last time repeatedly when applying once more by the most of absorption of wound surface; Eschar and slough can not effectively be got rid of, and reset procedure easily causes the wound surface damage; Crust operation and skin-grafting still need be cut, be cut to deep burn, increases the wound surface misery and increase the expense course of treatment.
Summary of the invention
The treatment burn that provides a kind of therapeutic effect good, the medicine of scalding and preparation method thereof are provided the object of the invention.
For reaching above-mentioned purpose, the present invention adopts following technical scheme: a kind of medicine for the treatment of burn, scalding, make by following materials based on weight: 200-500 part Oleum sesami, 5-30 part Cortex sophorae, 5-20 part Periostracum Serpentis.
The preparation method of the medicine of treatment burn, scald is got parts by weight 200-500 part Oleum sesami, 5-30 part Cortex sophorae, 5-20 part Periostracum Serpentis, and Cortex sophorae, Periostracum Serpentis are fused into the Oleum sesami mixing, and fried concentrating forms.
Cortex sophorae, Periostracum Serpentis are worn into fine powder fuse into the Oleum sesami mixing, fried concentrating forms.
Fried concentrated condition is 250-350 ℃ and boiled 1-2 hour.
The present invention is directed to the pathogeny and the Therapeutic Principle of burn disease; optimize Oleum sesami, Cortex sophorae, three kinds of biological raw materials of Periostracum Serpentis; effect prescription according to various biotic component pair cell tissues; adopt simple and medicine that scientific preparation process is made the treatment burn, scalded; without any side effects, efficacy stability having hemostasis dispel pain, removing pathogenic heat from blood and toxic substance from the body, infection by force; effects such as protection liver, renal function can be used for treating burn.
Drug use method of the present invention can not made debridement treatment, do not wrapped up wound surface for exposing wet treatment.Because it has strong permeability, directly be coated with (spray) and be put on wound surface and get final product.Detailed directions is every day 4-6 time, later stage 2-4 time, comes off until the incrustation nature.
The present invention has following good effect:
1, dispel painful fast.Medicine of the present invention is smeared behind the wound surface alleviating pain rapidly, whole therapeutic process no pain;
2, infection is strong.Medicine of the present invention has removing heat from blood, antidotal function, not only kills the various antibacterials of wound surface after smearing, and also by strong penetration, provides nutrient substance such as aminoacid, protein for the tissue of burn cell.Because nutrition is regularly constantly supplied with, provided circularly to medicine of the present invention, thereby the metabolite that reaches in the downright bad ecological organization of burn all can be discharged from wound surface, to organizing wound surface to create an airborne antibacterial intrusion not only capable of blocking but also moistening physiological environment being arranged.Also solved simultaneously the problem of wound tissue necrosis progrediens.
3, preventing from scar.Because the keratoprotein in the medicine of the present invention, the biological characteristics of fatty acid, reparation provides material guarantee to epidermis.So skin can progressively recover former skin state or approaching former skin state after the natural decrustation.Need not cut the crust skin-grafting.
4, medical expense is low.For the 1/50-1/10 (as the burn surface area of II degree 30%, drug cost is no more than 100 yuan) of equal burn expense treats in present China.
5, easy to use.Needn't remove wound surface before smearing, be applied to the nature decrustation always.Do not wrap up.
6, can adapt to various environment.Medicine of the present invention has formed a kind of protecting film to wound surface after smearing wound surface, and the antibacterial in blocking-up air and the sweat is invaded, so can be widely used in the common people and military affairs.
7, short treating period.Recovery from illness in slight 10-15 days; Dark the above 20-30 of II degree days.
8, medicine of the present invention is without any side effects, and permanently effective.
Be the 350 routine burn observation on Clinical Application reports that the applicant treats for many years below:
(1) physical data: in 350 examples, male 240 people, women 110 people.Age 2-65 year, shallow II degree 305 people of I-wherein, dark II-III degree is 44 people, the III degree is 1 people.
(2) diagnostic criteria: diagnostic criteria is diagnosed according to clinical practice I-III degree burn.
(3) administrated method: smear 4-6 time every day with medicine of the present invention, come off until the incrustation nature.
(4) curative effect judging standard:
Cure: after the burn incrustation came off, skin was moist, red slightly, no cicatrix.
Effectively: behind the topical agent, alleviating pain after 5 minutes.Progressively get rid of slough, blister slowly absorbs, incrustation, transudate reduce.
Take a turn for the better: after the wound surface incrustation, no transudate, last natural decrustation have gargalesthesia.
(5) result's statistics: among the shallow II degree of the I-patient, 60%, 15 day cure rate 40% of 10 days cure rates; Among the dark II-III degree patient, cure rate on the 20th cure rate 80% on the 20%, 30; III degree patient cured on the 40th.No cicatrix, no contracture deformity.
Model case is as follows:
Old XX, man, 52 years old.Get an electric shock morning August 22 calendar year 2001 when repairing the work of transformer belt electricity, and shirtfront and left limb are the III degree by third-degree burn, and palm is breakdown.To giving treatment to a week with silver sulfadiazine after, county people's hospital needs amputation and skin-grafting.Leave hospital because of financial difficulties and use Drug therapy of the present invention in the back, smearing surplus 30 day, and muscle is grown again, the approaching former skin state of top layer skin.Former skin state, no contracture deformity were recovered after the palm decrustation that punctures in 3 months.
In XX, woman, 8 years old.From the beginning arrived face by its mother's gruel and scald June 6 calendar year 2001.Smear with medicine of the present invention immediately, pain relief after 5 minutes, slowly incrustation in 3 days, the blister nature is absorbed by cortical tissue.Natural decrustation in 12 days, skin is red slightly, recovers former skin state after 6 months.Existing face does not show the vestige that any scald is crossed.
Lee XX, man, 35 years old.Be dark II degree by locomotive water tank scald when on June 8th, 2006, Mr. and Mrs two people were overturned, after orthopaedics hospital in county's is with purple water treatment, used Drug therapy of the present invention on the 3rd day.Smear after 5 minutes progressively alleviating pain, the purple Codium fragile (Sur.) Har. of wound surface was moving in second day, and the 4th day purple water comes off and is strip to polymerization together, and wound surface takes on a red color.Incrustation comes off after 20 days naturally after 10 days, recovery from illness.
More than three cases all do not do wound surface and remove to handle.
The specific embodiment
Embodiment 1, a kind of medicine for the treatment of burn, scalding are made by following materials based on weight: 200 parts of Oleum sesami, 5 parts of Cortex sophoraes, 5 parts of Periostracum Serpentiss.Preparation method is: get Oleum sesami, Cortex sophorae, Periostracum Serpentis by above-mentioned prescription, Periostracum Serpentis, Cortex sophorae are worn into fine powder dissolve in the Oleum sesami mixing, boil in 250 ℃ and formed in 1 hour.
In embodiment 2, the present embodiment, treatment burn, the medicine of scalding are made by following materials based on weight: 350 parts of Oleum sesami, 20 parts of Cortex sophoraes, 12 parts of Periostracum Serpentiss.Periostracum Serpentis, Cortex sophorae are worn into fine powder dissolve in the Oleum sesami mixing, boil in 300 ℃ and formed in 1.5 hours.
In embodiment 3, the present embodiment, treatment burn, the medicine of scalding are made by following materials based on weight: 500 parts of Oleum sesami, 30 parts of Cortex sophoraes, 20 parts of Periostracum Serpentiss.Periostracum Serpentis, Cortex sophorae are dissolved in Oleum sesami, boil in 350 ℃ and formed in 2 hours.
Claims (4)
1, a kind of medicine for the treatment of burn, scalding is characterized in that, is made by following materials based on weight: 200-500 part Oleum sesami, 5-30 part Cortex sophorae, 5-20 part Periostracum Serpentis; Get Oleum sesami, Cortex sophorae, the Periostracum Serpentis of described parts by weight, Cortex sophorae, Periostracum Serpentis are fused into the Oleum sesami mixing or Cortex sophorae, Periostracum Serpentis are worn into fine powder fuse into the Oleum sesami mixing, fried concentrating forms, and fried concentrated condition is 250-350 ℃ and boiled 1-2 hour.
2, the preparation method of the medicine of the described treatment burn of claim 1, scald is characterized in that, gets parts by weight 200-500 part Oleum sesami, 5-30 part Cortex sophorae, 5-20 part Periostracum Serpentis, and Cortex sophorae, Periostracum Serpentis are fused into the Oleum sesami mixing, and fried concentrating forms.
3, the preparation method of the medicine of treatment burn as claimed in claim 2, scald is characterized in that, Cortex sophorae, Periostracum Serpentis is worn into fine powder fuse into the Oleum sesami mixing, and fried concentrating forms.
4, as the preparation method of claim 2 or 3 described treatments burn, the medicine of scalding, it is characterized in that fried concentrated condition is 250-350 ℃ and boiled 1-2 hour.
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CNB2006101282087A CN100562324C (en) | 2006-11-15 | 2006-11-15 | A kind of medicine for the treatment of burn, scalding and preparation method thereof |
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CNB2006101282087A CN100562324C (en) | 2006-11-15 | 2006-11-15 | A kind of medicine for the treatment of burn, scalding and preparation method thereof |
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CN1965889A CN1965889A (en) | 2007-05-23 |
CN100562324C true CN100562324C (en) | 2009-11-25 |
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Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
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CN102370712B (en) * | 2011-10-25 | 2013-07-24 | 豆建全 | Traditional Chinese medicine ointment for treating burns and scalds without leaving any scar |
CN105250568A (en) * | 2015-11-17 | 2016-01-20 | 青岛益众生生物科技有限公司 | Medicinal composition for treating scalds and burns and preparation method thereof |
Citations (4)
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CN1205288A (en) * | 1996-06-11 | 1999-01-20 | 好孩子集团公司 | Bevel push handle rotation device of bevel shallow |
CN1313124A (en) * | 2001-03-14 | 2001-09-19 | 周华国 | Ointment for treating burn and its preparing process |
CN1390593A (en) * | 2002-07-19 | 2003-01-15 | 胡良桂 | Chinese-medicinal ointment for treating burn |
CN1475234A (en) * | 2002-08-14 | 2004-02-18 | 金日天 | A pharmaceutical composition for treating cancer |
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2006
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Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
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CN1205288A (en) * | 1996-06-11 | 1999-01-20 | 好孩子集团公司 | Bevel push handle rotation device of bevel shallow |
CN1313124A (en) * | 2001-03-14 | 2001-09-19 | 周华国 | Ointment for treating burn and its preparing process |
CN1390593A (en) * | 2002-07-19 | 2003-01-15 | 胡良桂 | Chinese-medicinal ointment for treating burn |
CN1475234A (en) * | 2002-08-14 | 2004-02-18 | 金日天 | A pharmaceutical composition for treating cancer |
Non-Patent Citations (6)
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中华本草. 国家中医药管理局《中华本草》编委会,第650页,右栏第29-30行,上海科学技术出版社出版. 1999 |
中华本草. 国家中医药管理局《中华本草》编委会,第650页,右栏第29-30行,上海科学技术出版社出版. 1999 * |
冰片的新用途. 孙仕田.医学文选,第Z1期. 1997 |
冰片的新用途. 孙仕田.医学文选,第Z1期. 1997 * |
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