CN100542620C - 药物注射装置的改进及其相关改进 - Google Patents

药物注射装置的改进及其相关改进 Download PDF

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CN100542620C
CN100542620C CNB028260996A CN02826099A CN100542620C CN 100542620 C CN100542620 C CN 100542620C CN B028260996 A CNB028260996 A CN B028260996A CN 02826099 A CN02826099 A CN 02826099A CN 100542620 C CN100542620 C CN 100542620C
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injection apparatus
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C·N·兰利
R·F·维齐
R·伍尔斯顿
S·A·戴
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Sanofi Aventis Deutschland GmbH
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    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M5/145—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M5/145—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
    • A61M5/1452—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons
    • A61M5/14566—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons with a replaceable reservoir for receiving a piston rod of the pump
    • A—HUMAN NECESSITIES
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    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/168—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
    • A—HUMAN NECESSITIES
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    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/31576—Constructional features or modes of drive mechanisms for piston rods
    • A61M2005/31588—Constructional features or modes of drive mechanisms for piston rods electrically driven
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/50—General characteristics of the apparatus with microprocessors or computers
    • A61M2205/52—General characteristics of the apparatus with microprocessors or computers with memories providing a history of measured variating parameters of apparatus or patient
    • A—HUMAN NECESSITIES
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    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/58—Means for facilitating use, e.g. by people with impaired vision
    • A61M2205/581—Means for facilitating use, e.g. by people with impaired vision by audible feedback
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/168—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
    • A61M5/16831—Monitoring, detecting, signalling or eliminating infusion flow anomalies
    • A—HUMAN NECESSITIES
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    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31525—Dosing
    • A—HUMAN NECESSITIES
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    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533—Dosing mechanisms, i.e. setting a dose
    • A61M5/31545—Setting modes for dosing
    • A61M5/31546—Electrically operated dose setting, e.g. input via touch screen or plus/minus buttons
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    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/31566—Means improving security or handling thereof
    • A61M5/3157—Means providing feedback signals when administration is completed
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    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/3159—Dose expelling manners
    • A61M5/31591—Single dose, i.e. individually set dose administered only once from the same medicament reservoir, e.g. including single stroke limiting means

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Abstract

本发明涉及一种药物注射装置，尤其适合于糖尿病人使用，在使用中，一旦选择了所需的药物剂量并将其从药物筒推进病人体内，在针头从病人体内抽出之前，使注射的药物可以在病人体内从注射部位局部地扩散。在已知的药物注射装置中存在这样的问题：注射间隔，即从前一次注射之后经过的时间，是在一次传送行程完成之后开始进行测量，而不是从注射药物的扩散之后开始进行测量。本发明公开了一种药物注射装置，其中一次注射操作之后经过的时间从一段预定时间结束时开始计算，在该段预定时间内可让药物在一次注射行程完成后进行扩散。

Description

药物注射装置的改进及其相关改进
技术领域
本发明涉及一种药物注射装置。本发明尤其，但并非唯一地用于电子控制的注射装置，由此能够进行一定药物剂量的自我给药。
背景技术
这种装置通常利用一储存药物的药物筒，并包括一控制一驱动机构的微处理器，以放送控制剂量的药物通过一针头装置。该装置足够小，以使使用者容易随身携带。这样，该装置尤其适合于患有糖尿病的人使用。
本发明也适合于其它种类的药物注射装置，例如，这样一种注射装置，其中尽管剂量设置和剂量传送在性质上是纯机械的，但定时器在一次剂量传送完成之后致动(启动)，以显示自该剂量传送完成后所经过的时间。
在各种情况下，使用时一旦选择了所需的药物剂量，药物注射装置的针头就***病人体内。然后致动驱动机构，以使所选药物剂量从药物筒排入至病人体内。
然而，在从病人体内抽出针头装置之前，需要一完成注射就使注射药物从病人体内的注射位置局部地扩散。
在已知的药物注射装置中存在这样的问题：注射间隔，即自前一次注射后所经过的时间，是在一次传送行程完成之后开始进行测量的，而不是从注射药物的扩散之后开始进行测量的。
发明内容
按照本发明的第一方面，在药物注射装置中，一次注射操作之后经过的时间是从一段预定时间结束时开始计算的，在此段预定时间内允许药物在一次注射行程完成后进行扩散。
这种注射装置具有注射间隔从扩散期间结束时开始测量的优点。
优选地，药物注射装置在注射操作完成之后提供一信号。这具有直到药物已被扩散之前使用者都不会不注意地抽出药物注射装置的优点。
按照本发明的第二方面，提供一种药物注射装置的操作方法，该药物注射装置包括一具有一定时器的处理器，一容纳药物的药物筒，一允许药物从药物筒推出的针头(针单元)和一使药物从药物筒推出的驱动装置，该方法包括以下步骤：
i)操作该驱动装置，以从药物筒推出药物；
ii)步骤i)完成时启动一定时器，以测量一段预定时间；
iii)步骤ii)完成时重新设置定时器，以测量自步骤ii)后所经过的时间。
优选地，步骤ii)也包括步骤ii)完成时产生一要发出的信号。
优选地，该方法还包括与步骤iii)同时显示自步骤ii)后所经过的时间。
附图说明
现将参照附图仅通过示例的方式对本发明进行描述，其中；
图1示例性地示出依据本发明的一种设置。
具体实施方式
参照附图，其公开了依据本发明的药物注射装置的一种示意性设置。该药物注射装置2包括一壳体4、一控制单元或微处理器6、一驱动装置8、一活塞10和一针头12。一优选为可更换的药物筒14位于活塞10和针头12之间。该药物筒14包括在第一端的适于由针头穿刺的一封闭件，和一位于朝向药物筒的第二端并适于由活塞10朝向药物筒14的第一端驱动的可移动的柱塞。
该控制单元或微处理器6包括一定时器(计时器)。在使用时，设定要注射的药物剂量。然后致动驱动装置8，以驱动活塞10。驱动装置8可机械致动或在控制单元或微处理器6的控制下致动。然后从药物注射装置2将药物筒14内的药物推出。
在所示的实施例中，微处理器6操纵驱动装置8使活塞10前移。然而，在一可选实施例中，可手动操作驱动装置使活塞前移。在后者的情况下，微处理器监控驱动装置的操作。在每种情况下，活塞被前移，以从药物筒内推出一定剂量的药物。
药物注射装置2也可包括实现已有技术中所需的和已知的其它功能的其它元件。
与控制单元或微处理器6相连的定时器在活塞10的运动——一次注射行程完成时致动。然后允许经过一段预定时间，以使得药物在病人体内扩散。这个第一段时间结束时，定时器重新设置为零并再一次致动。定时器现在记录依据本发明的注射间隔。
药物注射装置2可另外地结合一显示器16。显示器可方便地包括一LCD显示器。显示器16可用于指示注射间隔的持续时间。
药物注射装置2还可结合一信号装置18，例如一发声器，以给使用者提供扩散时间已过并可以抽出针头的信号。可选地，使用者可将显示器16上的注射间隔指示作为扩散时间已过的充分指示。
药物注射装置2的使用者首先操作药物注射装置2，以选择要由药物注射装置2注射的药物剂量。然后将针头12***病人体内，以便注射药物。然后操作药物注射装置2使活塞10前移。
然后使用者必须经过一段短暂的时间，以使药物扩散。如果针头12抽出太快，药物会通过针刺创口逸出，从而导致注射不恰当的药物剂量。这样，当注射行程之后已经过一段预定时间，微处理器6发出视觉和听觉信号任一种或这两种信号，以指示针头12可以从病人体内抽出。如果需要听觉信号，发声器18可用于产生该信号。
在给出信号的同时，微处理器6重新设定定时器为零，然后测量自给出信号后经过的时间。自给出信号后经过的时间可在显示器16上指示给使用者。

Claims (5)

1.一种药物注射装置，它构造成用以包含装有药物的药物筒(14)，该药物注射装置包括使药物从该药物筒推出的驱动装置(8)，其特征是还包括具有定时器的控制单元(6)，其中该定时器从该驱动装置完成一次注射操作时开始测量一段预定时间，在此段预定时间内可让药物在一次注射行程完成之后进行扩散，并且该控制单元(6)在该段预定时间结束时重新设定该定时器以测量该注射操作之后经过的时间。
2.一种根据权利要求1的药物注射装置，其特征是，该药物注射装置发出该注射操作结束的信号。
3.一种根据权利要求1或2的药物注射装置，其特征是，该药物注射装置还包括一指示该注射操作之后经过的时间的显示器。
4.一种根据权利要求1或2的药物注射装置，其特征是，该药物注射装置还包括指示从该驱动装置的注射操作完成后该段预定时间结束的装置。
5.一种根据权利要求3的药物注射装置，其特征是，该药物注射装置还包括指示从该驱动装置的注射操作完成后该段预定时间结束的装置。
CNB028260996A 2001-12-18 2002-12-16 药物注射装置的改进及其相关改进 Expired - Lifetime CN100542620C (zh)

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EP1465689A1 (en) 2004-10-13
BRPI0215190B1 (pt) 2016-01-12
CA2470651A1 (en) 2003-06-26
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US8617127B2 (en) 2013-12-31
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BR0215190A (pt) 2004-11-16
PL199003B1 (pl) 2008-08-29
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ZA200404858B (en) 2005-10-26
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AU2002366304B2 (en) 2009-08-06
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