CN100513565C - 编程性细胞死亡蛋白关联蛋白 - Google Patents
编程性细胞死亡蛋白关联蛋白 Download PDFInfo
- Publication number
- CN100513565C CN100513565C CNB008152551A CN00815255A CN100513565C CN 100513565 C CN100513565 C CN 100513565C CN B008152551 A CNB008152551 A CN B008152551A CN 00815255 A CN00815255 A CN 00815255A CN 100513565 C CN100513565 C CN 100513565C
- Authority
- CN
- China
- Prior art keywords
- apoptosis
- cell
- aap
- nucleic acid
- albumen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
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Images
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4747—Apoptosis related proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Biophysics (AREA)
- Veterinary Medicine (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Transplantation (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
Description
Claims (20)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP99202858.9 | 1999-09-02 | ||
EP99202858A EP1081226A1 (en) | 1999-09-02 | 1999-09-02 | Apoptin-associating protein |
EP99203465A EP1108785A1 (en) | 1999-10-21 | 1999-10-21 | Apoptin-associating protein |
EP99203465.2 | 1999-10-21 |
Publications (2)
Publication Number | Publication Date |
---|---|
CN1387569A CN1387569A (zh) | 2002-12-25 |
CN100513565C true CN100513565C (zh) | 2009-07-15 |
Family
ID=26153361
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CNB008152551A Expired - Fee Related CN100513565C (zh) | 1999-09-02 | 2000-09-01 | 编程性细胞死亡蛋白关联蛋白 |
Country Status (20)
Country | Link |
---|---|
US (2) | US7317096B1 (zh) |
EP (1) | EP1083224B1 (zh) |
JP (1) | JP2003510030A (zh) |
CN (1) | CN100513565C (zh) |
AT (1) | ATE347597T1 (zh) |
AU (1) | AU781127B2 (zh) |
BR (1) | BR0013743A (zh) |
CA (1) | CA2383784A1 (zh) |
CY (1) | CY1106355T1 (zh) |
DE (1) | DE60032201T2 (zh) |
DK (1) | DK1083224T3 (zh) |
EA (1) | EA005933B1 (zh) |
ES (1) | ES2277815T3 (zh) |
HU (1) | HUP0202688A2 (zh) |
IL (2) | IL148469A0 (zh) |
NO (1) | NO20021067L (zh) |
NZ (1) | NZ517740A (zh) |
PL (1) | PL204275B1 (zh) |
PT (1) | PT1083224E (zh) |
WO (1) | WO2001016165A2 (zh) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL150134A0 (en) * | 1999-12-10 | 2002-12-01 | Leadd Bv | Apoptin-associating protein |
WO2009126920A2 (en) | 2008-04-11 | 2009-10-15 | Merrimack Pharmaceuticals, Inc. | Human serum albumin linkers and conjugates thereof |
WO2011100428A2 (en) * | 2010-02-10 | 2011-08-18 | The Uab Research Foundation | Compositions for improving bone mass |
Family Cites Families (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NL9002008A (nl) * | 1990-09-12 | 1992-04-01 | Stichting Centr Diergeneeskund | Recombinant dna en rna en daarvan afgeleide produkten. |
EP0878546A1 (en) * | 1997-04-15 | 1998-11-18 | Leadd B.V. | A gene delivery vehicle expressing the apoptosis-inducing proteins VP2 and/or apoptin |
ATE305514T1 (de) | 1994-12-22 | 2005-10-15 | Novartis Pharma Gmbh | Nukleäre protein serin/threoninkinasen |
ES2200065T3 (es) * | 1995-06-07 | 2004-03-01 | Leadd B.V. | Utilizacion de apoptina. |
CA2283299A1 (en) | 1997-03-07 | 1998-09-11 | Human Genome Sciences, Inc. | 186 human secreted proteins |
SK286235B6 (sk) * | 1997-08-12 | 2008-06-06 | Leadd B. V. | Spôsob zisťovania transformačnej schopnosti látky, spôsob zisťovania predispozície buniek stať sa nádorovými bunkami, použitie nukleovej kyseliny a diagnostická súprava |
EP0924296A3 (en) * | 1997-12-03 | 2001-08-01 | Leadd B.V. | Methods and means for inducing apoptosis by interference in RNA processing |
EP0927757A1 (en) * | 1997-12-03 | 1999-07-07 | Leadd B.V. | Methods and means for inducing apoptosis by interfering with Bip-like proteins |
EP0921192A1 (en) * | 1997-12-03 | 1999-06-09 | Leadd B.V. | Molecules interacting with apoptin |
US20030105315A1 (en) | 1998-04-09 | 2003-06-05 | Metagen Pharmaceuticals Gmbh | Human nucleic acid sequences from ovarian tumor tissue |
JP2002513554A (ja) * | 1998-05-05 | 2002-05-14 | インサイト・ファーマスーティカルズ・インコーポレイテッド | ヒト転写調節分子 |
EP1111045A3 (en) | 1999-12-10 | 2001-09-19 | Leadd B.V. | Apoptin-associating protein |
IL150134A0 (en) | 1999-12-10 | 2002-12-01 | Leadd Bv | Apoptin-associating protein |
EP1106691A1 (en) | 1999-12-10 | 2001-06-13 | Leadd B.V. | Apoptin-associating protein |
AU3422801A (en) | 2000-01-17 | 2001-07-31 | Leadd B.V. | Apoptin-associating protein |
EP1138765A1 (en) | 2000-03-27 | 2001-10-04 | Leadd B.V. | Apoptin-associating proteins AAP-5 and AAP-6 |
-
2000
- 2000-09-01 AU AU73242/00A patent/AU781127B2/en not_active Ceased
- 2000-09-01 JP JP2001519726A patent/JP2003510030A/ja active Pending
- 2000-09-01 PT PT00203042T patent/PT1083224E/pt unknown
- 2000-09-01 CN CNB008152551A patent/CN100513565C/zh not_active Expired - Fee Related
- 2000-09-01 AT AT00203042T patent/ATE347597T1/de not_active IP Right Cessation
- 2000-09-01 EP EP00203042A patent/EP1083224B1/en not_active Expired - Lifetime
- 2000-09-01 HU HU0202688A patent/HUP0202688A2/hu unknown
- 2000-09-01 ES ES00203042T patent/ES2277815T3/es not_active Expired - Lifetime
- 2000-09-01 PL PL354285A patent/PL204275B1/pl not_active IP Right Cessation
- 2000-09-01 CA CA002383784A patent/CA2383784A1/en not_active Abandoned
- 2000-09-01 BR BR0013743-0A patent/BR0013743A/pt active Pending
- 2000-09-01 DK DK00203042T patent/DK1083224T3/da active
- 2000-09-01 IL IL14846900A patent/IL148469A0/xx active IP Right Grant
- 2000-09-01 DE DE60032201T patent/DE60032201T2/de not_active Expired - Lifetime
- 2000-09-01 WO PCT/NL2000/000612 patent/WO2001016165A2/en active IP Right Grant
- 2000-09-01 NZ NZ517740A patent/NZ517740A/en unknown
- 2000-09-01 EA EA200200321A patent/EA005933B1/ru not_active IP Right Cessation
- 2000-09-05 US US09/655,109 patent/US7317096B1/en not_active Expired - Fee Related
-
2002
- 2002-03-03 IL IL148469A patent/IL148469A/en not_active IP Right Cessation
- 2002-03-04 NO NO20021067A patent/NO20021067L/no not_active Application Discontinuation
-
2007
- 2007-03-06 CY CY20071100310T patent/CY1106355T1/el unknown
- 2007-06-12 US US11/818,169 patent/US7767790B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
DE60032201T2 (de) | 2007-09-20 |
DE60032201D1 (de) | 2007-01-18 |
DK1083224T3 (da) | 2007-04-10 |
IL148469A (en) | 2009-02-11 |
PL204275B1 (pl) | 2009-12-31 |
HUP0202688A2 (en) | 2002-12-28 |
EA005933B1 (ru) | 2005-08-25 |
AU781127B2 (en) | 2005-05-05 |
ATE347597T1 (de) | 2006-12-15 |
NZ517740A (en) | 2003-09-26 |
NO20021067L (no) | 2002-05-02 |
EA200200321A1 (ru) | 2002-08-29 |
NO20021067D0 (no) | 2002-03-04 |
BR0013743A (pt) | 2005-01-11 |
WO2001016165A2 (en) | 2001-03-08 |
PL354285A1 (en) | 2003-12-29 |
JP2003510030A (ja) | 2003-03-18 |
CN1387569A (zh) | 2002-12-25 |
WO2001016165A3 (en) | 2001-09-20 |
AU7324200A (en) | 2001-03-26 |
ES2277815T3 (es) | 2007-08-01 |
PT1083224E (pt) | 2007-03-30 |
CA2383784A1 (en) | 2001-03-08 |
EP1083224B1 (en) | 2006-12-06 |
CY1106355T1 (el) | 2011-10-12 |
US20080176231A1 (en) | 2008-07-24 |
EP1083224A3 (en) | 2001-04-25 |
IL148469A0 (en) | 2002-09-12 |
US7317096B1 (en) | 2008-01-08 |
US7767790B2 (en) | 2010-08-03 |
EP1083224A2 (en) | 2001-03-14 |
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Publication | Publication Date | Title |
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CN100513565C (zh) | 编程性细胞死亡蛋白关联蛋白 | |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
C06 | Publication | ||
PB01 | Publication | ||
C10 | Entry into substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
CI01 | Publication of corrected invention patent application |
Correction item: Inventor Correct: Astrid Adriana Anna Mary|Sub - South - Fanaoersihuote False: Astrid Adriana Anna Mary|Sub - South - Fanaoersihuote Number: 52 Volume: 18 |
|
CI02 | Correction of invention patent application |
Correction item: Inventor Correct: Astrid Adriana Anna Mary|Sub - South - Fanaoersihuote False: Astrid Adriana Anna Mary|Sub - South - Fanaoersihuote Number: 52 Page: The title page Volume: 18 |
|
C14 | Grant of patent or utility model | ||
GR01 | Patent grant | ||
C17 | Cessation of patent right | ||
CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20090715 Termination date: 20100901 |