CN100493548C - Cosmetic formulation for skin spot-eliminating, whitening and wrinkle-removing, and its preparing method - Google Patents
Cosmetic formulation for skin spot-eliminating, whitening and wrinkle-removing, and its preparing method Download PDFInfo
- Publication number
- CN100493548C CN100493548C CNB2005102003927A CN200510200392A CN100493548C CN 100493548 C CN100493548 C CN 100493548C CN B2005102003927 A CNB2005102003927 A CN B2005102003927A CN 200510200392 A CN200510200392 A CN 200510200392A CN 100493548 C CN100493548 C CN 100493548C
- Authority
- CN
- China
- Prior art keywords
- extract
- vitamin
- angelicae sinensis
- radix angelicae
- eliminating
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Landscapes
- Cosmetics (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The present invention relates to face-beautifying preparation with the functions of removing facial chloasma, whitening facial skin and removing facial wrinkles. Said face-beautifying preparation contains 6 ingredients of rose extract, Chinese angelica root extract, carthamus flower extract, grape seed extract, vitamin C and vitamin E. Besides, said invention also provides its preparation method.
Description
(1) technical field
The present invention relates to a kind of health product useful, particularly a kind of cosmetic health product to health.
(2) background technology
Liking to be beautiful is people's nature, and face skin U.S.A is the human beautiful main aspect of pursuing.Because a variety of causes, chloasma, pigmentation and wrinkle appear in human face skin unavoidably.Doctor trained in Western medicine thinks that this is a kind of common chromatopathy, and the traditional Chinese medical science thinks that this is the Liver and kidney deficiency of YIN-blood, and QI and blood is not smooth, due to the face mistake is supported.Just become technical barrier and human eternal pursuit and dispel these specklees, pigmentation and wrinkle.Existing cosmetic formulation has external and the interior branch of using, external comprise some beauty treatment and eliminating spot cream, unguentum etc.; Interior have the Lac regis apis of comprising with cosmetic formulation, pollen, natural materials such as Margarita powder, also usually select for use some Chinese crude drugs to make Coryza Treated by Syndrome Differentiation, for example select Radix Angelicae Sinensis for use, the Radix Angelicae Dahuricae, Flos Carthami, Rhizoma Chuanxiong, the Radix Paeoniae Alba, Radix Rehmanniae Preparata, the Radix Polygoni Multiflori, Radix Salviae Miltiorrhizae, Fructus Jujubae, Rhizoma Zingiberis Recens, Pericarpium Citri Reticulatae, Rhizoma Polygonati Odorati, the west Qi, Ganoderma, Caulis Spatholobi, Herba Apocyni veneti, Radix Bupleuri, Radix Et Rhizoma Rhei, Radix Curcumae, Bombyx Batryticatus, the Radix Astragali, Radix Ginseng, Radix Glycyrrhizae, Rhizoma Atractylodis, Fructus Hippophae, Radix Saposhnikoviae, Radix Notoginseng, Poria, bentonite, Aloe, Folium Ginkgo, Rhizoma Typhonii, zinc oxide, Herba Leonuri, Sal Ammoniacus, Gypsum Fibrosum powder, Radix Paeoniae Rubra, the Radix Rehmanniae, Radix Puerariae, parasitic, Radix Scrophulariae, Rhizoma Polygoni Cuspidati, Rhizoma Corydalis, Hirudo, Pollen Typhae, Oletum Trogopterori, Cortex Cinnamomi, Rhizoma Cyperi or the like is used as medicine.In general, the face beautifying medicine that many Chinese crude drugs are made has many side effect, therefore is unsuitable for taking for a long time.In fact, in nature, also have many materials not to be familiar with as yet by people with aesthetic health care.Though what have is familiar with, is not found suitable compatibility by the mankind as yet.
(3) summary of the invention
The present invention to provide a kind of to skin spot-eliminating, brighten, the cosmetic formulation of wrinkle removing and preparation method thereof, solve the technical problem that skin speckle, pigment, wrinkle are removed in the combination of Chinese and Western medicine; And solve the problem that cosmetic formulation is taken toxic side effect for a long time.
Technical scheme of the present invention: thisly give skin spot-eliminating, brighten, the cosmetic formulation of wrinkle removing, it is characterized in that: contain in the said preparation with aromatic oil be effective ingredient Flos Rosae Rugosae extract, be the Radix Angelicae Sinensis extract of main effective ingredient, be the Flos Carthami extract of effective ingredient, be six kinds of compositions of Semen Vitis viniferae extract, vitamin C, vitamin E of effective ingredient with the procyanidin with phthalide analog compound with the Carthamus yellow.One of weight proportion of above-mentioned preparation:
Flos Rosae Rugosae extract: 5～90%,
Flos Carthami extract: 3～40%,
Semen Vitis viniferae extract: 1～32%,
Radix Angelicae Sinensis extract: 4～14%,
Vitamin C: 1～9%,
Vitamin E: 1～9%.
Two of the weight proportion of above-mentioned preparation:
Flos Carthami extract: 5～90%,
Flos Rosae Rugosae extract: 3～40%,
Semen Vitis viniferae extract: 1～32%,
Radix Angelicae Sinensis extract: 4～14%,
Vitamin C: 1～9%,
Vitamin E: 1～9%.
Three of the weight proportion of above-mentioned preparation:
Semen Vitis viniferae extract: 5～90%,
Flos Carthami extract: 3～40%,
Flos Rosae Rugosae extract: 1～32%,
Radix Angelicae Sinensis extract: 4～14%,
Vitamin C: 1～9%,
Vitamin E: 1～9%.
Four of the weight proportion of above-mentioned preparation:
Semen Vitis viniferae extract: 5～90%,
Flos Rosae Rugosae extract: 3～40%,
Flos Carthami extract: 1～32%,
Radix Angelicae Sinensis extract: 4～14%;
Vitamin C: 1～9%;
Vitamin E: 1～9%.
Five of the weight proportion of above-mentioned preparation:
Flos Carthami extract: 5～90%,
Radix Angelicae Sinensis extract: 3～40%,
Flos Rosae Rugosae extract: 1～32%,
Semen Vitis viniferae extract: 4～14%;
Vitamin C: 1～9%;
Vitamin E: 1～9%.
Thisly give skin spot-eliminating, brighten, the preparation method of the cosmetic formulation of wrinkle removing, it is characterized in that following steps are arranged:
(1), choose fresh, pure with aromatic oil be effective ingredient Flos Rosae Rugosae extract, with phthalide analog compound be
The Radix Angelicae Sinensis extract of main effective ingredient, be the Flos Carthami extract of effective ingredient with the Carthamus yellow, be that the Semen Vitis viniferae extract of effective ingredient and vitamin C, E powder are standby with the procyanidin;
(2), above raw material was mixed 40 minutes with mixer;
(3), said mixture is crossed 80 mesh sieves;
(4), pack, go out finished product.
Component of the present invention is selected compatibility principle and beneficial effect:
Flos Carthami is Compositae annual herb plant.Its extract property and flavor of peppery and warm, the bitter in the mouth suffering is gone into the heart, Liver Channel, has promoting blood circulation to restore menstrual flow, and the analgesic effect of going to become silted up is a promoting blood flow and remove blood stasis drug commonly used simply.Flos Carthami contains carthamin, and organic principles such as neocarthamin and Flos Carthami quinone glycoside also contain trace element such as chromium, manganese, zinc-copper.The function blood circulation promoting and blood stasis dispelling, regulating menstruation cures mainly amenorrhea due to stagnation of blood, diseases such as dysmenorrhea, puerperal abdonimal pain, traumatic injury.The present invention plays promoting blood circulation to remove obstruction in the collateral with Flos Carthami extract, silt releasing and analgesia, anticoagulant effect.Experimentation proof Carthamus yellow has the effect of the inductive rabbit platelet aggregation of inhibition adenosine triphosphate of highly significant.And to the cohesion platelet tangible depolymerisation is also arranged.Coronary flow when increasing heart and myocardial ischemia prolongs clotting time, and fortifying fibre protein dissolution activity plays promoting blood circulation to restore menstrual flow, the effect of the silt dissipating rashes of dispelling.
Flos Rosae Rugosae is a Rosaceae solitary flower defoliation bush plant, and its extract includes aromatic oil, the flower aubergine, and fragrant odour, according to medicine book " detailed outline is picked up any lost article from the road " record, Flos Rosae Rugosae is invigorated blood circulation, promoting the circulation of blood, spleen invigorating pathogenic fire reducing, regulating QI to promote menstruation, nourishing skin care.Good medicinal efficacy is arranged.The present invention is by Flos Rosae Rugosae extract vital energy regualting and blood circulation-promoting, dispersing the stagnated live-QI to relieve the stagnation of QI, the comprehensively regulating gastrointestinal function.By the content of glutathione in the vitamin C increase body, reduce the vigor of tyrosine, suppress the oxidation of DOPA, stop melanic formation, suppress the pigementation in the skin.
Radix Angelicae Sinensis is Umbelliferae, angelica, and the dry root of Radix Angelicae Sinensis is enriched blood, regulating menstruation, pain-relieving functions.Its main chemical compositions has: phthalide analog compound, coumarin kind compound, flavone compound, organic acid and aminoacid, trace element etc.Radix Angelicae Sinensis can improve blood circulation.1, can improve the peripheral circulation effect: can reduce vascular resistance, increase femoral artery blood flow, increase the peripheral blood flow, improve local microcirculation, the skin expansion blood vessel.2, improve cerebral circulation.Butylphthalide is one of Radix Angelicae Sinensis main component, can increase MCAO postoperative pia mater encephali arteriole caliber and blood flow rate, thereby improves the pia mater encephali microcirculation.The present invention increases MCAO postoperative pia mater encephali arteriole caliber and blood flow rate by Radix Angelicae Sinensis extract, thereby improves the pia mater encephali microcirculation, reduces vascular resistance, increases femoral artery blood flow, increases the peripheral blood flow, improves local microcirculation, the skin expansion blood vessel.
Semen Vitis viniferae extract; its main component is procyanidin (Grape Seed Extract Proantbocyanidin; GSPE); confirm through scientific experiments; the Semen Vitis viniferae extract procyanidin is strong effectively one of free radical scavenger, its health care Wheat Protein, protection cardiovascular and prophylaxis of hypertension effect, antitumor, radioprotective, mutation, antiallergic, improves visual performance and skin care beautification function.The present invention effectively removes interior free yl by the Semen Vitis viniferae extract procyanidin, the generation of blocking-up elastoser also suppresses its activity, prevent lipid peroxide (LPO) accumulation, prevent skin free radical over oxidation, make the excessive glue of collagen protein connect wrinkling a, vesicle, impel the appropriate glue of collagen protein to connect.
The vitamin C of one of component of the present invention can suppress DOPA (DOPA) oxidation, and makes melanin be converted into colourless reduction melanocyte.
The vitamin E of one of component of the present invention also is a kind of antioxidant, and it removes free radical according to the nationality antioxidation, suppresses the generation of lipid peroxide, thereby has suppressed melanic calmness.
The present invention has absorbed the elite of China's tradition traditional Chinese medical science speckle dispelling therapy, abandoned the bigger component of toxic and side effects, combine with Radix Angelicae Sinensis extract, Flos Carthami extract, Flos Rosae Rugosae extract, be used for activating blood circulation to dissipate blood stasis, conditioning endocrine, improve hemorheology and microcirculation, blood circulation promoting improves skin colour from the endogenous cause of ill and the aspect of effecting a permanent cure, and increases skin elasticity.
The present invention also adopts vitamin C, vitamin E and Semen Vitis viniferae extract compound, in order to block melanic reaction, reduces melanic generation.Melanin is synthetic a kind of high-molecular biologic pigment in the melanocyte, its route of synthesis is: in melanocyte, tyrosine forms DOPA through tyrosinase catalysis, form the DOPA quinone behind the DOPA dehydrogenation, the latter rearranges into 5,6-quinone indole, combining the formation melanoprotein with the intravital structural protein of melanin after its generation polymerization is melanin.After melanin is synthetic, is transported to epithelial cells from melanocyte, and permeates into each layer of epidermis, disappear with exfoliation at last with the maturation of epithelial cells.And by some cause of disease influence, the melanin Developmental and Metabolic Disorder, the excretory melanin of melanocyte increases, and causes local skin black excessively, forms chloasma.The active oxygen (OR) that ultraviolet produces can promote the reaction that melanocyte forms; LPO (lipid peroxide) external can be caused pigmentation; and can protect subcutaneous tissue to avoid the infringement of OR as the L-SOD (superoxide dismutase) of OR remover; LPO raises 5 times in the chloasma sebum; raise more behind the ultraviolet radiation, so its symptom changes relevant with the LPO value.Vitamin C, vitamin E are one of powerful antioxidants of generally acknowledging, Semen Vitis viniferae extract then is the efficient antioxidants of finding up to now of a kind of plant origin, and its oxidation resistance is vitamin C and vitamin E 20 and 50 times.They rely on antioxidation, have prevented the accumulation of LPO.Can also suppress the oxidation of DOPA, stop melanic formation.
The present invention adopts pure natural non-toxic herb extract and Semen Vitis viniferae extract, VC and VE compatibility, the combination of Chinese and Western medicine, and synergism, internal and external application makes human viscera organ's conditioning and dispels free radical and work along both lines, and not only effects a permanent cure but also control table.Detect proof through Beijing Disease Prevention and Control Centre: the present invention belongs to nontoxic level through animal mouth toxicity test, PCEMNR micronucleus test, mouse sperm deformity test, Salmonella reversion test, 30 days feeding trials of animal.Through animal feeding test, weight increase, food-intake, food utilization, hematological indices and the blood biochemical of animal are learned aspects such as index, internal organs weight in wet base and dirty/body compare there is no obvious influence.Histopathologic examination does not see that the significant histopathology relevant with being tried thing changes yet.
The chloasma-dispelling function human feeding trial that carries out through Xiyuan Hospital, Chinese Medicine Academy of China detects proof in addition: the present invention has no adverse effects to the experimenter is healthy.This test is divided into test-meal group and blank group at random by 100 routine chloasma experimenters, and every group 50 example, test-meal group were on request taken the capsule made by the present invention 30 days, and test-meal group chloasma area on average dwindles 10.84 ± 14.50cm
2(P＜0.01), color shoals, and colour atla on average reduces by 0.37 ± 0.48 degree (P＜0.01), effective 30 examples, total effective rate 60.00%.Matched group chloasma area on average dwindles 0.06 ± 1.86cm
2, color shoals, and colour atla on average reduces by 0.01 ± 0.21 degree, effective 2 examples, total effective rate 4.00%.Before and after experimenter's test-meal, routine blood test, routine urinalysis, just routine and blood biochemistry index be all in normal range.Illustrate that the present invention does not have any allergy and harmful effect to health, also can improve symptoms such as human-body fatigue, agitation, dyssomnia.
Eating method of the present invention and amount: every day 2 times, each 2, warm water takes.Specification: 260 milligrams/.
Instant of the present invention is taken for a long time and is had no side effect, and has activating blood circulation to dissipate blood stasis, the effect that conditioning endocrine and blocking-up melanin generate, and effectively eliminating chloasma prevents that skin from corrugating, the needs that the satisfied mankind like to be beautiful.
(4) specific embodiment
Embodiment is just like table 1:
Contain Flos Rosae Rugosae extract, Flos Carthami extract, Semen Vitis viniferae extract, Radix Angelicae Sinensis extract in the preparation of the present invention, vitamin C, six kinds of materials of vitamin E.Its weight proportion is as follows:
Flos Rosae Rugosae extract: 5～90%, Flos Carthami extract: 3～40%, Semen Vitis viniferae extract: 1～32%, Radix Angelicae Sinensis extract 4～14%, vitamin C: 1～9%, vitamin E: 1～9%.
| Table 1: | |||||
| Flos Rosae Rugosae extract (%) | Flos Carthami extract (%) | Semen Vitis viniferae extract (%) | Radix Angelicae Sinensis extract (%) | VC (％) | VE (％) |
| 90 | 3 | 1 | 4 | 1 | 1 |
| 85 | 5 | 4 | 4 | 1 | 1 |
| 75 | 8 | 8 | 5 | 2 | 2 |
| 65 | 12 | 12 | 5 | 3 | 3 |
| 55 | 14 | 16 | 7 | 4 | 4 |
| 45 | 16 | 20 | 9 | 5 | 5 |
| 35 | 21 | 22 | 10 | 6 | 6 |
| 25 | 28 | 28 | 5 | 7 | 7 |
| 15 | 35 | 30 | 14 | 8 | 8 |
| 5 | 40 | 32 | 5 | 9 | 9 |
Embodiment two is as table 2: its weight proportion is as follows:
Flos Carthami extract: 5～90%, Flos Rosae Rugosae extract: 3～40%, Semen Vitis viniferae extract: 1～32%, Radix Angelicae Sinensis extract: 4～14%, vitamin C: 1～9%, vitamin E: 1～9%.
| Table 2: | |||||
| Flos Carthami extract (%) | Flos Rosae Rugosae extract (%) | Semen Vitis viniferae extract (%) | Radix Angelicae Sinensis extract (%) | VC (％) | VE (％) |
| 90 | 3 | 1 | 4 | 1 | 1 |
| 85 | 5 | 4 | 4 | 1 | |
| 75 | 8 | 8 | 5 | 2 | 2 |
| 65 | 12 | 12 | 5 | 3 | 3 |
| 55 | 14 | 16 | 7 | 4 | 4 |
| 45 | 16 | 20 | 9 | 5 | 5 |
| 35 | 21 | 22 | 10 | 6 | 6 |
| 25 | 28 | 28 | 5 | 7 | 7 |
| 15 | 35 | 30 | 14 | 8 | 8 |
| 5 | 40 | 32 | 5 | 9 | 9 |
Embodiment three is as table 3: its weight proportion is as follows:
Semen Vitis viniferae extract: 5～90%, Flos Carthami extract: 3～40%, Flos Rosae Rugosae extract: 1～32%, Radix Angelicae Sinensis extract: 4～14%, vitamin C: 1～9%, vitamin E: 1～9%.
| Table 3: | |||||
| Semen Vitis viniferae extract (%) | Flos Carthami extract (%) | Flos Rosae Rugosae extract (%) | Radix Angelicae Sinensis extract (%) | VC (％) | VE (％) |
| 90 | 3 | 1 | 4 | 1 | 1 |
| 85 | 5 | 4 | 4 | 1 | |
| 75 | 8 | 8 | 5 | 2 | 2 |
| 65 | 12 | 12 | 5 | 3 | 3 |
| 55 | 14 | 16 | 7 | 4 | 4 |
| 45 | 16 | 20 | 9 | 5 | 5 |
| 35 | 21 | 22 | 10 | 6 | 6 |
| 25 | 28 | 28 | 5 | 7 | 7 |
| 15 | 35 | 30 | 14 | 8 | 8 |
| 5 | 40 | 32 | 5 | 9 | 9 |
Embodiment four is as table 4: its weight proportion is as follows:
Semen Vitis viniferae extract: 5～90%, Flos Rosae Rugosae extract: 3～40%, Flos Carthami extract: 1～32%, Radix Angelicae Sinensis extract: 4～14%; Vitamin C: 1～9%; Vitamin E: 1～9%.
| Table 4: | |||||
| Semen Vitis viniferae extract (%) | Flos Rosae Rugosae extract (%) | Flos Carthami extract (%) | Radix Angelicae Sinensis extract (%) | VC (％) | VE (％) |
| 90 | 3 | 1 | 4 | 1 | 1 |
| 85 | 5 | 4 | 4 | 1 | 1 |
| 75 | 8 | 8 | 5 | 2 | 2 |
| 65 | 12 | 12 | 5 | 3 | 3 |
| 55 | 14 | 16 | 7 | 4 | 4 |
| 45 | 16 | 20 | 9 | 5 | 5 |
| 35 | 21 | 22 | 10 | 6 | 6 |
| 25 | 28 | 28 | 5 | 7 | 7 |
| 15 | 35 | 30 | 14 | 8 | 8 |
| 5 | 40 | 32 | 5 | 9 | 9 |
Embodiment five is as table 5: its weight proportion is as follows:
Flos Carthami extract: 5～90%, Radix Angelicae Sinensis extract: 3～40%, Flos Rosae Rugosae extract: 1～32%, Semen Vitis viniferae extract: 4～14%; Vitamin C: 1～9%; Vitamin E: 1～9%.
| Table 5: | |||||
| Flos Carthami extract (%) | Radix Angelicae Sinensis extract (%) | Flos Rosae Rugosae extract (%) | Semen Vitis viniferae extract (%) | VC (％) | VE (％) |
| 90 | 3 | 1 | 4 | 1 | 1 |
| 85 | 5 | 4 | 4 | 1 | 1 |
| 75 | 8 | 8 | 5 | 2 | 2 |
| 65 | 12 | 12 | 5 | 3 | 3 |
| 55 | 14 | 16 | 7 | 4 | 4 |
| 45 | 16 | 20 | 9 | 5 | 5 |
| 35 | 21 | 22 | 10 | 6 | 6 |
| 25 | 28 | 28 | 5 | 7 | 7 |
| 15 | 35 | 30 | 14 | 8 | 8 |
| 5 | 40 | 32 | 5 | 9 | 9 |
Thisly give skin spot-eliminating, brighten, the preparation method of the cosmetic formulation of wrinkle removing, following steps are arranged:
(1), choose fresh, pure Flos Rosae Rugosae extract, Radix Angelicae Sinensis extract, Flos Carthami extract, Semen Vitis viniferae extract and vitamin C, the E powder is standby;
(2), above raw material was mixed 40 minutes with mixer;
(3), said mixture is crossed 80 mesh sieves;
(4), fill, be packaged into capsule finished product with No. 1 hard capsule.
Vitamin C, vitamin E can adopt the patent medicine of pharmaceutical factory.The preparation method of above-mentioned Flos Rosae Rugosae extract, Flos Carthami extract, Radix Angelicae Sinensis extract belongs to the common practise of Chinese medicine industry,
Flos Rosae Rugosae extract: Flos Rosae Rugosae → pulverizing → decocting in water → concentrate → spray drying.
Flos Carthami extract: Flos Carthami → pulverizing → decocting in water → concentrate → spraying → drying.
Radix Angelicae Sinensis extract: Radix Angelicae Sinensis raw material → clean and crush → 90% alcohol extraction → concentrate → add cycloheptaamylose → vacuum drying.
The preparation method of Semen Vitis viniferae extract belongs to known field equally, and embodiment can be referring to Chinese patent application prospectus CN1357325A, also can as shown in the formula:
Semen Vitis viniferae → three times → filtration → concentrating under reduced pressure of 70% alcohol extraction → deionized water dissolving → centrifugal filtration → filtrate → chromatographic column → water, low alcohol, high alcohol is eluting successively:
Water lotion → discard.
Low alcohol eluen → concentrating under reduced pressure → 95% ethanol precipitate with ethanol → supernatant → concentrate → spray drying;
High alcohol eluen → recovery ethanol.
Claims (7)
- [claim 1] a kind of gives skin spot-eliminating, brighten, the cosmetic formulation of wrinkle removing, it is characterized in that: said preparation by with aromatic oil be effective ingredient Flos Rosae Rugosae extract, be the Radix Angelicae Sinensis extract of main effective ingredient, be the Flos Carthami extract of effective ingredient, be that six kinds of compositions of Semen Vitis viniferae extract, vitamin C, vitamin E of effective ingredient are made with the procyanidin with phthalide analog compound with the Carthamus yellow.
- [claim 2] according to claim 1 gives skin spot-eliminating, brighten, the cosmetic formulation of wrinkle removing, and it is characterized in that: the weight proportion of above-mentioned preparation is as follows:Flos Rosae Rugosae extract: 5～90%;Flos Carthami extract: 3～40%;Semen Vitis viniferae extract: 1～32%;Radix Angelicae Sinensis extract: 4～14%;Vitamin C: 1～9%;Vitamin E: 1～9%.
- [claim 3] according to claim 1 gives skin spot-eliminating, brighten, the cosmetic formulation of wrinkle removing, and it is characterized in that: the weight proportion of above-mentioned preparation is as follows:Flos Carthami extract: 5～90%,Flos Rosae Rugosae extract: 3～40%,Semen Vitis viniferae extract: 1～32%,Radix Angelicae Sinensis extract: 4～14%;Vitamin C: 1～9%Vitamin E: 1～9%.
- [claim 4] according to claim 1 gives skin spot-eliminating, brighten, the cosmetic formulation of wrinkle removing, and it is characterized in that: the weight proportion of above-mentioned preparation is as follows: Semen Vitis viniferae extract: 5～90%,Flos Carthami extract: 3～40%,Flos Rosae Rugosae extract: 1～32%,Radix Angelicae Sinensis extract: 4～14%;Vitamin C: 1～9%;Vitamin E: 1～9%.
- [claim 5] according to claim 1 gives skin spot-eliminating, brighten, the cosmetic formulation of wrinkle removing, and it is characterized in that: the weight proportion of above-mentioned preparation is as follows:Semen Vitis viniferae extract: 5～90%,Flos Rosae Rugosae extract: 3～40%,Flos Carthami extract: 1～32%,Radix Angelicae Sinensis extract: 4～14%;Vitamin C: 1～9%;Vitamin E: 1～9%.
- [claim 6] according to claim 1 gives skin spot-eliminating, brighten, the cosmetic formulation of wrinkle removing, and it is characterized in that: the weight proportion of above-mentioned preparation is as follows:Flos Carthami extract: 5～90%,Radix Angelicae Sinensis extract: 3～40%,Flos Rosae Rugosae extract: 1～32%,Semen Vitis viniferae extract: 4～14%;Vitamin C: 1～9%;Vitamin E: 1～9%.
- [claim 7] a kind of gives skin spot-eliminating, brighten, the preparation method of the cosmetic formulation of wrinkle removing, it is characterized in that following steps are arranged:(1), choose fresh, pure with aromatic oil be effective ingredient Flos Rosae Rugosae extract, be the Radix Angelicae Sinensis extract of main effective ingredient, be the Flos Carthami extract of effective ingredient, be that the Semen Vitis viniferae extract of effective ingredient and vitamin C, E powder are standby with the procyanidin with phthalide analog compound with the Carthamus yellow;(2), above raw material was mixed 40 minutes with mixer;(3), said mixture is crossed 80 mesh sieves;(4), pack, go out finished product.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2005102003927A CN100493548C (en) | 2005-07-14 | 2005-07-14 | Cosmetic formulation for skin spot-eliminating, whitening and wrinkle-removing, and its preparing method |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2005102003927A CN100493548C (en) | 2005-07-14 | 2005-07-14 | Cosmetic formulation for skin spot-eliminating, whitening and wrinkle-removing, and its preparing method |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1709474A CN1709474A (en) | 2005-12-21 |
| CN100493548C true CN100493548C (en) | 2009-06-03 |
Family
ID=35705805
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNB2005102003927A Active CN100493548C (en) | 2005-07-14 | 2005-07-14 | Cosmetic formulation for skin spot-eliminating, whitening and wrinkle-removing, and its preparing method |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN100493548C (en) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101352497B (en) * | 2007-07-26 | 2011-11-09 | 株洲千金药业股份有限公司 | Chinese medicinal composition for removing chloasma, and preparation method and uses thereof |
| CN101112466B (en) * | 2007-07-31 | 2010-09-22 | 浙江杭州鑫富药业股份有限公司 | Compound composition for treating chloasma and stimulating evacuation of the bowels and uses thereof |
| CN101116506B (en) * | 2007-08-31 | 2010-12-22 | 北京因科瑞斯医药科技有限公司 | Health products having functions of improving skin moisture |
| CN101112237B (en) * | 2007-08-31 | 2010-12-22 | 北京因科瑞斯医药科技有限公司 | Health products having a function of dispelling chloasma |
| CN101332274B (en) * | 2008-07-15 | 2011-05-11 | 武汉理工大学 | Compound grape-seed cream and preparation method thereof |
| CN101715960B (en) * | 2008-12-02 | 2013-10-02 | 天津天狮生物发展有限公司 | Beauty capsule and production and manufacturing process thereof |
| CN101524320B (en) * | 2009-04-17 | 2011-02-02 | 武汉名实生物医药科技有限责任公司 | Compound preparation capable of freckle-removing, skin-whitening, moisture preservation and wrinkle-resistance |
| CN102441028A (en) * | 2010-12-23 | 2012-05-09 | 马英祥 | Composition with speckle lightening and removing effects, preparation method and application thereof |
| CN102258638B (en) * | 2011-08-17 | 2012-10-03 | 深圳华博生物科技发展有限公司 | Anti-aging plant extract composition and preparation method and application thereof |
| CN103006920B (en) * | 2011-12-14 | 2015-05-06 | 西安泰科迈医药科技有限公司 | Chloasma-removing pure traditional Chinese medicine composition and preparation method thereof |
| CN102657745A (en) * | 2012-05-17 | 2012-09-12 | 双飞人制药（中国）有限公司 | Medicinal composition with effect of removing chloasma |
| CN102772351B (en) * | 2012-08-18 | 2014-07-16 | 马林超 | Pearl E cream |
| CN102949567A (en) * | 2012-11-23 | 2013-03-06 | 西安泰科迈医药科技有限公司 | Medicinal capsule for removing chloasma and preparation method thereof |
| CN103734693A (en) * | 2013-11-21 | 2014-04-23 | 荣成百合生物技术有限公司 | Beauty treatment and face nourishment health tablet and preparation method thereof |
| CN104041636B (en) * | 2014-06-25 | 2016-04-27 | 湖南中医药大学 | Chinese medicine health-care jasmine tea of a kind of fat reducing of improving looks and preparation method thereof |
| CN104547309A (en) * | 2014-12-25 | 2015-04-29 | 湖南炎帝生物工程有限公司 | Traditional Chinese medicine composition for removing chloasma, and preparation method and application thereof |
| CN106110308B (en) * | 2016-06-28 | 2017-12-12 | 陈俊杰 | It is a kind of that breast enlargement can be allowed to compact and prevent the Essence of mammary gland disease |
| CN111990644A (en) * | 2020-08-28 | 2020-11-27 | 西安皇家医疗保健品有限公司 | Grape seed and rose composition with chloasma removing effect and preparation method thereof |
-
2005
- 2005-07-14 CN CNB2005102003927A patent/CN100493548C/en active Active
Non-Patent Citations (2)
| Title |
|---|
| 天然活性物美白功效的细胞生物学研究. 杨亚军等.日用化学工业，第2002卷第3期. 2002 |
| 天然活性物美白功效的细胞生物学研究. 杨亚军等.日用化学工业，第2002卷第3期. 2002 * |
Also Published As
| Publication number | Publication date |
|---|---|
| CN1709474A (en) | 2005-12-21 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN100493548C (en) | Cosmetic formulation for skin spot-eliminating, whitening and wrinkle-removing, and its preparing method | |
| KR101676601B1 (en) | External preparation for skin comprising herbal extracts as an active ingredient and manufacturing method thereof | |
| CN105920085B (en) | Composition with attenuation effect and preparation method and application thereof | |
| CN101703623A (en) | Capsule with effect of relieving physical fatigue | |
| CN105288246A (en) | Whitening and anti-wrinkle traditional Chinese medicine composition as well as mixed extract and application thereof | |
| CN109288931A (en) | A kind of composition for treating infant eczema, preparation and preparation method and application | |
| CN102836098A (en) | Chinese medicinal herb composition beauty essence | |
| CN1840036A (en) | Chinese medicinal composite preparation capable of inhibiting growth of tumor cell | |
| CN102000271A (en) | Oral medicament for removing acne | |
| KR101307718B1 (en) | Soap for improving atopic dermatitis, acne and psoriasis | |
| CN102133167B (en) | Freckle removing facial mask made of traditional Chinese medicine and preparation process thereof | |
| CN105535477B (en) | The Chinese medicine composition of anti-ageing beauty treatment | |
| KR101622104B1 (en) | COMPOSITION FOR PREVENTING, TREATING OR IMPROVING SKIN DISEASE, COMPRISING EXTRACT OF Cassia obtussifolia L. AND EXTRACT OF Hovenia ducis | |
| CN110179708A (en) | A kind of plant assigns essential oil living and preparation method | |
| CN104274649A (en) | Medicine for treating oral ulcer | |
| CN102988266A (en) | Traditional Chinese medicine shampoo containing Chinese angelica | |
| CN105687522A (en) | Pharmaceutical composition with chloasma removing function and preparation method thereof | |
| KR20170136930A (en) | Composition for improving skin condition comprising herb extracts mixture | |
| CN112386560A (en) | A skin caring and speckle removing product containing Chinese medicinal components, and its preparation method | |
| CN106822300B (en) | Traditional Chinese medicine preparation for removing acne and beautifying face | |
| CN108379199A (en) | A kind of plant mask powder | |
| CN104352775A (en) | Medicine for treating angina pectoris of coronary atherosclerotic heart disease | |
| CN106619238A (en) | Composition for treating chloasma | |
| CN105663758A (en) | Folium artemisiae argyi containing traditional Chinese medicine composition for treating irregular menstruation and preparation method thereof | |
| CN111840093A (en) | Hierarchical structure and formula of whitening mask |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant |