CN100464698C - Pulse condition detecting device capable of automatically regulating pulse-feeling pressure and pulse condition characteristic extracting method - Google Patents
Pulse condition detecting device capable of automatically regulating pulse-feeling pressure and pulse condition characteristic extracting method Download PDFInfo
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- CN100464698C CN100464698C CNB2006100096391A CN200610009639A CN100464698C CN 100464698 C CN100464698 C CN 100464698C CN B2006100096391 A CNB2006100096391 A CN B2006100096391A CN 200610009639 A CN200610009639 A CN 200610009639A CN 100464698 C CN100464698 C CN 100464698C
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Abstract
The present invention relates to a pulse condition detection equipment capable of automatically regulating pressure for feeling the pulse and its pulse condition characteristics extraction method. It is characterized by that the invented equipment can utilize central control circuit to control step-by-step motor to pressurize or depressurize pressure sensor so as to obtain the pulse condition information of cun, guan and chi of wrist under the different pressures.
Description
Technical field
The present invention relates to medical sensing device, promptly a kind of Chinese medicine pulse checkout gear that uses based on Multi-sensor Fusion belongs to the Medical Instruments technical field.
Background technology
Pulse-taking is one of traditional Chinese medical science four diagnostic methods, occupies important status in tcm diagnosis.To be the Chinese physician press three positions of cun,guan,chi, patient's the area on the wrist over the radial artery where the pulse is felt for diagnosis radial artery place with finger to the common way of pulse wave spectrum, by finger apply floating, in, different pressure such as heavy experiences the variation of patient's pulse wave.Corresponding to floating, in, heavy equal pressure and produce a series of comprised pulse drift along, the pulse wave of power, trend, shape, width and rhythm and pace of moving things or the like information, we are referred to as pulse condition.From pulse condition information, the doctor can know that pulse is floating or heavy, is real or void, is greatly or little, is soon or slow.By these information, the doctor just can understand patient's pathological state.But this traditional pulse wave spectrum has very big subjectivity; The process of diagnosis is difficult to reproduce, and is difficult to learn, and spends several years even the more than ten years could be grasped.
In order to solve the shortcoming of traditional pulse wave spectrum, for many years, many research workers have made unremitting effort aspect the objectifying of pulse-taking.The key that objectifies of pulse wave spectrum is obtaining of high-quality pulse signal.Along with the continuous progress of sensor technology, designed increasing pulse image sensor.Chinese patent 89107657.3 involved " doctor's pulse-feeling sensing device " is wherein typically arranged.This device is with the media of sense capsule as feeling the pulse, and the sense capsule contacts the arteries and veins position of human body, and the pulse signal that obtains is transferred to pressure transducer through the sensing body canal, converts the signal of telecommunication to by pressure transducer then.The weak point of this device is: adopt the usual pressure pick off, the arteries and veins shape signal of being gathered only can can't extract enough detailed arteries and veins shape signal, thereby can not support the pulse condition diagnosis of more complicated for the simple pulse condition diagnosis of minority provides foundation.Chinese invention patent 86107766 has proposed a kind of " Chinese medicine pulse checkout gear ", the shortcoming of this device is: because the rigid surface of dynamometry sensing element and softish people refer to the difference on surface, this force-measuring type transducer can not take into account floating pulse and in, the detection and the diagnosis of deep pulse.The scheme of 00119603.0 pair of patent 86107766 of Chinese invention patent application has been carried out certain improvement, utilize the series hybrid pulse condition to improve the floating pulse power of test, but since in, use single channel dynamometry sensing element when deep pulse detects, this scheme can't be described for complicated pulse condition provide detailed digital." pulse detecting device, pollex checkout gear and the pressure-detecting device " that Chinese patent 98800694.4 is announced adopts piezoelectric transducer to measure pulse wave; " the pulse wave spectrum sensor-based system " that Chinese patent 2003101005513.0 is announced is to adopt piezoelectric transducer directly to measure pulse wave equally.At present the pulse condition information of these pick offs reflections is all more single, and has the inaccurate shortcoming in location, the automatic adjusting of the pressure of can not realizing equally feeling the pulse.The traditional Chinese medical science thinks that pulse condition mainly contains aspect information such as " position ", " shape ", " gesture ", " number ", and the feature of the pulse condition that objectifies also has research, but does not see the concrete report that the numerical characteristic extracting method is arranged.
Summary of the invention
For solve existing pulse condition detection device can't realize feeling the pulse pressure automatic adjusting and gather contraction and the diastole displacement information that cun,guan,chi three place's vasculars are beaten simultaneously, and traditional pulse condition feature extracting method can't provide the problem of accurate information for analyzing pulse condition each side such as " position, shape, gesture, numbers " simultaneously, the invention provides a kind of pulse condition detection device of automatic adjusting feeling the pulse pressure, it has mainly merged photoelectric sensor and pressure transducer and measures under different feeling the pulse pressure vascular and shrink displacement information with diastole.
Chinese medicine pulse checkout gear of the present invention is made up of automatic pressurization machinery, first photoelectric sensor, second photoelectric sensor, the 3rd photoelectric sensor, pressure transducer, amplifying circuit, A/D change-over circuit, central control circuit and step motor drive controller; Automatically the pressurization machinery mainly comprises inner shell, shell, three photoelectric sensor trailing frames, the pressure gear frame, motor and vertical link, the non-induction end of described pressure transducer links to each other by described vertical link with the moment output shaft of described motor, the pressure sensitive end of described pressure transducer contacts with bottom centre's point of described pressure gear frame, and the sidewall of described pressure gear frame is fixedlyed connected with described inner shell, the lateral wall of described inner shell is connected with the medial wall longitudinal sliding motion of described shell, described three photoelectric sensor trailing frames are positioned at the below of described pressure gear frame, described first photoelectric sensor, second photoelectric sensor and the 3rd photoelectric sensor are separately fixed at the lower end of described three photoelectric sensor trailing frames, and the bottom surface of described three photoelectric sensor trailing frames is fixedly connected on respectively on the inner bottom surface of described inner shell; Described first photoelectric sensor, second photoelectric sensor, the data output end of the 3rd photoelectric sensor and pressure transducer is connected four inputs of amplifying circuit respectively, the analog signal output of described amplifying circuit connects the input of described A/D change-over circuit, the data output end of described A/D change-over circuit connects the data input pin of described central control circuit, the motor control signal outfan of described central control circuit connects the control signal input of described step motor drive controller, and the driving signal output part of described step motor drive controller connects the driving signal input of described motor.
Adopt the pulse condition feature extracting method of cun,guan,chi three place's pulse waves that checkout gear of the present invention obtains to comprise the extracting method and the dynamic Feature Extraction method of pulse of pulse static nature.Wherein the extracting method of pulse wave static nature carries out according to the following steps: one, input contains the pulse wave at pseudo-peak, utilize crest height than (Proportion to Peak ' s Height PPH) detects the number in pulse condition cycle and the number at the peak in each cycle; Two, detect the starting point and the terminal point of above-mentioned pulse wave, and calculate their cycle; Three, find the peak in each cycle to be main peak, and obtain respectively they main crest amplitude and the pulse wave starting point to the duration (corresponding to the phase of maximum ejection of left ventricle) of main wave crest point; Four, judge that whether the number at peak in each cycle of the pulse wave that the first step obtains is more than or equal to three; If the judged result in 5 the 4th steps is sure, then searches for backward and find first valley point to be main ripple gorge, and try to achieve their main ripple gorge amplitude respectively according to the peak position in each cycle; Six, search for backward according to the main Bo Xia position in each cycle and find first peak dot to be the dicrotic pulse prewave, and try to achieve their amplitude of dicrotic pulse prewave and the peak height of dicrotic pulse prewave respectively; Seven, search for backward according to crest location before the dicrotic pulse in each cycle and find first valley point to be dicrotic notch, and try to achieve the amplitude, pulse wave starting point of their dicrotic notch systole area, pulse wave relaxing period area respectively to the duration between the dicrotic notch (corresponding to the systole of left ventricle), pulse wave; Eight, search for backward according to the dicrotic notch position in each cycle and find first peak dot to be dicrotic wave, and try to achieve the amplitude and the peak height of their dicrotic wave respectively; Nine, calculate the width of the main peak in each cycle; Ten, in the series of features value of calculating, count the static nature of its intermediate value as this pulse condition; If the judged results in 11 steps negate, whether the number at peak in each cycle of then judging the pulse wave that the first step obtains if the judged result in ten one step be sure, then carries out seven step to ten step more than or equal to two; If judging whether of the 11 step is fixed, then carried out for the 9th step to the tenth step.The dynamic Feature Extraction of above-mentioned pulse wave is carried out according to the following steps: the extracting method of 01 step, the above-mentioned pulse condition static nature of utilization to obtain the cycle of pulse wave under each cycle, main crest amplitude, main ripple gorge amplitude, the amplitude of dicrotic pulse prewave, the peak height of dicrotic pulse prewave, the number at peak and is a characteristic sequence, and calculates the standard deviation of above-mentioned characteristic sequence; 02 the step, above-mentioned pulse wave analysis image is carried out Fourier transform; 3Hz is with interior low-frequency content energy summation and between the ratio of 5Hz to the energy summation of high frequency between the 25Hz in 03 step, the calculating pulse wave frequency spectrum; 04 goes on foot, extracts with Meyer (Meyer) small echo the envelope of pulse wave frequency spectrum; The summit in 05 step, the detection pulse wave spectrum envelope and the position and the amplitude thereof on inferior peak; 06 step, according to the pulse wave different feeling the pulse pressure under, acquisition pulse wave pulse pressure-amplitude curve; 07 step, from pulse wave pulse pressure-amplitude curve, extract pulse pressure-amplitude curve main peak width of 80% of pairing pulse pressure of maximum amplitude and maximum amplitude.
Operation principle: three photoelectric sensors corresponding respectively three positions of cun,guan,chi of human body wrist, their inside is made up of light emitting diode and phototriode, the infrared light that is sent by light emitting diode when detecting pulse condition reflects through skin, can be received by phototriode, their usefulness be that wavelength is the infrared light of 950nm, very responsive to HbO2 Oxyhemoglobin and hemoglobin, can capture fluctuating of arterial blood tube wall, through having extraordinary linear characteristic after the calibration; Pressure transducer is placed on the top of photoelectric sensor, is used for obtaining feeling the pulse pressure.Described central control circuit 9 control step motors rotate, the rotation meeting of motor drives the pressure gear frame by motor shaft and vertical link and moves up and down, the mobile meeting of pressure gear frame finally drives inner housing moving up and down with respect to patient's wrist, thereby can be provided in when detecting pulse condition required floating, in, feeling the pulse pressure such as heavy, the pressure size that provides adopts classical pid control algorithm by the central control circuit closed loop control; Pressure transducer and three resulting pulse condition analogue signals of photoelectric sensor are sent in the analog-digital converter after nursing one's health amplifying circuit; Central control circuit generation A/D conversion start signal is being controlled analog-digital converter signal is being sampled, analog signal conversion is become digital signal, and the result after being responsible for changing is sent in the described central control circuit and stores, and by fusion treatment detected pulse condition information is presented on the screen, be convenient to operator's observation.
The amplitude of these pulse waves that feature extracting method use device of the present invention obtains is made pulse wave pulse pressure-amplitude curve with their corresponding feeling the pulse pressure.In the numerical characteristic that method of the present invention is extracted, 14 static natures comprise pulse condition time domain waveform vpg connection feature, the i.e. number at H1, the H2 among Fig. 7 and Fig. 8, H3, H32, H4, H5, H54, t1, t4, As, Ad, W, T, pulse wave peak; 13 behavioral characteristics comprise the dispersion feature (being the dispersion of the number at H1, H2, H3, H32, T, pulse wave peak) of position (being the pairing pulse pressure of maximum amplitude in pulse wave pulse pressure-amplitude curve), gesture feature (being the curve width of 80% place correspondence of maximum amplitude in pulse wave pulse pressure-amplitude curve) and 6 static natures of 5 frequency domain characters (being the position and the amplitude at peak on the highest, the inferior peak of spectrum envelope), pulse condition; The dispersion of T and T can characterize the feature of the number of pulse wave.Adopt the extracting method of static nature of the present invention and behavioral characteristics can obtain to be used for characterizing the accurate information of aspects such as Chinese medicine pulse " position ", " shape ", " gesture ", " number ".
The invention effect: the present invention a kind ofly obtains pulse profile data in AT mode, and to its equipment of handling and analyzing.Checkout gear of the present invention adopts photoelectric sensor, compare with " electropulsograph " that the Chinese patent 92113134.8 of same employing photoelectric sensor is announced, can gather the pulse condition of cun,guan,chi three tunnel simultaneously, and having increased the device of automatic adjusting feeling the pulse pressure, checkout gear of the present invention also can add the information that sonac gets access to blood flow rate simultaneously; Feature extracting method of the present invention can obtain the static parameter and the dynamic parameter of pulse condition, and it provides exact figure information for " position ", " shape ", " gesture ", " number " of analyzing pulse condition.Device of the present invention is easy to carry, plug and play; Method of the present invention has merged the detection of photoelectric sensor and pressure transducer, and the pulse condition information of human body is quantized, and it is objective to have realized the subjectivity that traditional Chinese medicine pulse detects is changed into.
Description of drawings
Fig. 1 is a structural representation of the present invention; Fig. 2 is the cross-sectional view of automatic pressurization machinery 1 of the present invention; Fig. 3 is the vertical view of Fig. 2; Fig. 4 is the electrical block diagram of the specific embodiment of the invention seven; Fig. 5 is the flow chart of pulse wave static nature extracting method of the present invention; Fig. 6 is the flow chart of the dynamic feature extracting method of pulse wave of the present invention; Fig. 7 is the form parameter of arteries and veins figure, vertical coordinate is represented amplitude, and H1 is main crest amplitude among the figure, and H2 is a main ripple gorge amplitude, H3 is the amplitude of dicrotic pulse prewave, H32 is the peak height of dicrotic pulse prewave, and H4 is the amplitude of dicrotic notch, and H5 is the amplitude of dicrotic wave, H54 is the peak height of dicrotic wave, T is the duration of pulse wave one-period, and t1 is the duration of pulse wave starting point to main wave crest point, and W is the width of main peak; Fig. 8 is the area parameters of arteries and veins figure, and vertical coordinate is represented the pulse wave amplitude, t4 be the pulse wave starting point to the duration between the dicrotic notch, As is the systole area, Ad is the relaxing period area; Fig. 9 is the pulse wave figure that employing checkout gear of the present invention detects three positions of cun, guan and chi, three places at the wrist where the pulse is usually taken simultaneously, abscissa express time (second), and vertical coordinate is represented the pulse wave amplitude; Figure 10 adopts the pulse condition figure of checkout gear of the present invention under the difference feeling the pulse pressure that CUN obtains, Z direction indication pulse wave amplitude, directions X express time, Y direction indication feeling the pulse pressure; Figure 11 is the pulse wave pulse pressure-amplitude curve figure of three position pulse conditions of cun, guan and chi, three places at the wrist where the pulse is usually taken, and abscissa is represented the pressure of feeling the pulse, and vertical coordinate is represented the pulse wave amplitude; Figure 12 is the sketch maps of the specific embodiment eight camber than PPH, and h1, h2, h3 are the amplitude at peak among the figure; Figure 13 is the graph of relation of the specific embodiment eight camber than the number N at PPH-peak.
The specific embodiment
The specific embodiment one: referring to Fig. 1 and Fig. 2, Chinese medicine pulse checkout gear of the present invention is made up of automatic pressurization machinery 1, first photoelectric sensor 2, second photoelectric sensor 3, the 3rd photoelectric sensor 4, pressure transducer 5, amplifying circuit 7, A/D change-over circuit 8, central control circuit 9 and step motor drive controller 10; Automatically pressurization machinery 1 mainly comprises inner shell 1-6, shell 1-5, three photoelectric sensor trailing frame 1-1, pressure gear frame 1-2, motor 6 and vertical link, the non-induction end of described pressure transducer 5 links to each other by described vertical link with the moment output shaft of described motor 6, the pressure sensitive end of described pressure transducer 5 contacts with bottom centre's point of described pressure gear frame 1-2, and the sidewall of described pressure gear frame 1-2 is fixedlyed connected with described inner shell 1-6, the lateral wall of described inner shell 1-6 is connected with the medial wall longitudinal sliding motion of described shell 1-5, described three photoelectric sensor trailing frame 1-1 are positioned at the below of described pressure gear frame 1-2, described first photoelectric sensor 2, second photoelectric sensor 3 and the 3rd photoelectric sensor 4 are separately fixed at the lower end of described three photoelectric sensor trailing frame 1-1, and the bottom surface of described three photoelectric sensor trailing frame 1-1 is fixedly connected on respectively on the inner bottom surface of described inner shell 1-6; Described first photoelectric sensor 2, second photoelectric sensor 3, the data output end of the 3rd photoelectric sensor 4 and pressure transducer 5 is connected four inputs of amplifying circuit 7 respectively, the analog signal output of described amplifying circuit 7 connects the input of described A/D change-over circuit 8, the data output end of described A/D change-over circuit 8 connects the data input pin of described central control circuit 9, the motor control signal outfan of described central control circuit 9 connects the control signal input of described step motor drive controller 10, and the driving signal output part of described step motor drive controller 10 connects the driving signal input of described motor 6.Pressure transducer 5 can sensitively be experienced the variation of pressure for the pick off of some contact, and converts thereof into voltage signal output, and its model that adopts is FSL05N2C; The inside of described first photoelectric sensor 2, second photoelectric sensor 3 and the 3rd photoelectric sensor 4 all is made up of light emitting diode and phototriode, and the model of employing is CNY70.
The specific embodiment two: referring to Fig. 1, this specific embodiment with the difference of the specific embodiment one is: described pulse condition detection device also comprises sonac and interface module 11, and described sonac and interface module 11 link to each other with the blood flow detection signal input part of described central control circuit 9.Other compositions are identical with the specific embodiment one with annexation.Sonac is used to survey blood flow rate, and blood flow rate slows down and the blood flow resistance index increase has certain relation; The sonac that the present invention adopts and the model of interface module 11 are CBS-900.The information fusion that the present invention for the first time acquires photoelectric sensor, pressure transducer and sonac, thus quantized the pulse condition information of the more traditional Chinese medical science, and realize pulse condition detection device obtaining to pulse condition " fluent degree " information.
The specific embodiment three: referring to Fig. 2 and Fig. 3, this specific embodiment with the difference of the specific embodiment one is: described automatic pressurization machinery 1 comprises that also three transducer transverselies drag screw rod 1-10, the upper end of each photoelectric sensor trailing frame 1-1 is fixedly connected with a transducer transversely respectively and drags screw rod 1-10, and described transducer transversely drags screw rod 1-10 and is threaded with the upper end of photoelectric sensor trailing frame 1-1.Other compositions are identical with the specific embodiment one with annexation.Each photoelectric sensor all has a transducer transversely to drag screw rod 1-10 in the probe outside, but the position of lateral adjustments pick off is used for the position that accurate alignment sensor is placed on three ones of cun,guan,chis; Only found the accurate in locating position, just can make the pick off correspondence the strongest position of pulse wave.
The specific embodiment four: referring to Fig. 2 and Fig. 3, this specific embodiment with the difference of the specific embodiment one is: in the machinery 1 that pressurizes automatically, described vertical link vertically drags screw rod 1-3-2 by pick off, the driving block 1-3-1 and the first screw 1-4 form, the central axis that described pick off vertically drags the torque transmitting axle 6-1 of the central axis of screw rod 1-3-2 and described motor 6 coincides, and radially fixedly connected by the first screw 1-4 with described moment output shaft 6-1 in the upper end that described pick off vertically drags screw rod 1-3-2, the internal circular surfaces that described driving block 1-3-1 is provided with longitudinal hole and described through hole is provided with female thread, the outer round surface that described pick off vertically drags screw rod 1-3-2 lower end is threaded with the upper end internal circular surfaces that described driving block 1-3-1 goes up through hole, described driving block 1-3-1 goes up the centrage of through hole and the central axis that described pick off vertically drags screw rod 1-3-2 coincides, and the non-induction end of described pressure transducer 5 is bonded on the lower surface of described driving block 1-3-1.Other compositions are identical with the specific embodiment one with annexation.When motor output shaft rotated, pick off vertically dragged screw rod 1-3-2 and also and then rotates, and promoted driving block 1-3-1 lengthwise movement simultaneously to photoelectric sensor pressurization or release pressure.Before adopting automatic pressurization machinery 1 of the present invention to detect pulse condition, it has been carried out the calibration work of pressurization, make checkout gear can determine the size that photoelectric sensor is exerted pressure accurately.
The specific embodiment five: referring to Fig. 2, this specific embodiment with the difference of the specific embodiment one is: described automatic pressurization machinery 1 also comprises carriage 1-7, and described carriage 1-7 is fixed on the lower end of described shell 1-5.Other compositions are identical with the specific embodiment one with annexation.Carriage 1-7 side is arc line type, is convenient to people's installation and carries.Carriage adopts the design of watchband type, meets the design of ergonomics, and the use of watchband has reduced the relative displacement of pick off and wrist, makes the location more accurate.
The specific embodiment six: referring to Fig. 2 and Fig. 3, this specific embodiment with the difference of the specific embodiment one is: described automatic pressurization machinery 1 also comprises two second screw 1-9, former and later two sidewalls of described pressure gear frame 1-2 are fixedlyed connected by two second screw 1-9 respectively with former and later two sidewalls of described inner shell 1-6, the left-external side wall 1-6-2 of described inner shell 1-6, the left medial wall 1-5-2 of described shell 1-5, all be provided with longitudinal rail on the right lateral wall 1-6-1 of described inner shell 1-6 and the Right Inboard wall 1-5-1 of described shell 1-5, and the left-external side wall 1-6-2 of described inner shell 1-6 is connected with the left medial wall 1-5-2 longitudinal sliding motion of described shell 1-5, and the right lateral wall 1-6-1 of described inner shell 1-6 is connected with the Right Inboard wall 1-5-1 longitudinal sliding motion of described shell 1-5.Other compositions are identical with the specific embodiment one with annexation.The sidewall that is provided with longitudinal rail can be an one with inner shell or shell, also can be the parts with the band guide rail of inner shell or shell strong bond.
The specific embodiment seven: referring to Fig. 1 and Fig. 4, this specific embodiment with the difference of the specific embodiment two is: described amplifying circuit 7 is made up of three groups of conditioning amplifying circuit 7-1 and pressure amplifying circuit 7-2, every group of conditioning amplifying circuit 7-1 is by zero adjustment circuit 7-1-1, first order amplifying circuit 7-1-2, filter circuit 7-1-3 and second level amplifying circuit 7-1-4 form, the input of the zero adjustment circuit 7-1-1 of every group of conditioning amplifying circuit 7-1 connects the data output end of a photoelectric sensor that links to each other with this group conditioning amplifying circuit 7-1, the outfan of the zero adjustment circuit 7-1-1 of every group of conditioning amplifying circuit 7-1 links to each other with the input of the first order amplifying circuit 7-1-2 of this group, the outfan of the first order amplifying circuit 7-1-2 of every group of conditioning amplifying circuit 7-1 links to each other with the input of the filter circuit 7-1-3 of this group, the outfan of the filter circuit 7-1-3 of every group of conditioning amplifying circuit 7-1 links to each other with the input of the second level amplifying circuit 7-1-4 of this group, and the data output end of pressure transducer 5 connects the input of pressure amplifying circuit 7-2; Described A/D change-over circuit 8 is by A/D modular converter 8-1, latch 8-2, buffer 8-3 forms, described central control circuit 9 is by host computer 9-2, usb interface module 9-3, slave computer control circuit 9-1 forms, the outfan of the second level amplifying circuit 7-1-4 of every group of conditioning amplifying circuit 7-1 links to each other with the photosignal input of A/D modular converter 8-1, the outfan of described pressure amplifying circuit 7-2 connects the pressure signal input of described A/D modular converter 8-1, the data output end of described A/D modular converter 8-1 by described buffer 8-3 respectively with usb interface module 9-3, the data input pin of slave computer control circuit 9-1 and latch 8-2 links to each other, the latch signal outfan of described slave computer control circuit 9-1 connects the control end of described latch 8-2, the data output end of described latch 8-2 connects the channel selecting control end of described A/D modular converter 8-1, the cache control signal outfan of described slave computer control circuit 9-1 connects the control end of described buffer 8-3, the A/D changeover control signal outfan of described slave computer control circuit 9-1 connects the control end of described A/D modular converter 8-1, described slave computer control circuit 9-1 reads, the write signal outfan connects reading of described usb interface module 9-3 respectively, write control end, the Electric Machine Control end of described slave computer control circuit 9-1 connects the control signal input of described step motor drive controller 10, the FPDP of described usb interface module 9-3 connects the FPDP of described host computer 9-2, and sonac and interface module 11 link to each other with the blood flow detection FPDP of described host computer 9-2 by USB interface.It is the A/D conversion chip of ADS7864Y that above-mentioned A/D modular converter 8-1 adopts model; It is the chip that latchs of SN54HC373 that above-mentioned latch 8-2 adopts model; It is the cache chip of HC244 that above-mentioned buffer 8-3 adopts model; The master chip of above-mentioned slave computer control circuit 9-1 is 8-bit microcontroller P89C52, in order to match with the A/D conversion chip, the PLD that a then additional model is LC4064V25T44-51 comes assistant SCM to carry out control work, its effect is to latch output latch and output enable control signal, enable control signal to the buffer pio chip, and to A/D modular converter output changeover control signal and data read signal, because the voltage of some control signal is not enough, has then also added a chip that boosts that model is 74HC004; It is the USB interface chip of PDIUSBD12 that above-mentioned usb interface module 9-3 adopts model; It is the driving chip of SAA1042V that above-mentioned step motor drive controller 10 adopts model.Other compositions are identical with the specific embodiment two with annexation.Pressure signal amplifies through one-level sends into analog-digital converter, and photosignal need advance two-stage and amplifies and just can enter into analog-digital converter.Be provided with zeroing function among the conditioning amplifying circuit 7-1 of the present invention, with convenient calibration; It can also be removed power frequency and disturb and high-frequency noise, and entire circuit can guarantee that pulse signal is undistorted.
The specific embodiment eight: referring to Fig. 5, this specific embodiment is an example with the pulse condition static nature that obtains CUN, its extracting method carries out according to the following steps: one, input contains the pulse wave (pulse wave of isolated CUN from Fig. 9) at pseudo-peak, utilizes crest height recently to detect the number in pulse condition cycle and the number at the peak in each cycle; Two, detect the starting point and the terminal point of above-mentioned pulse wave, and calculate their cycle; Three, find the peak in each cycle to be main peak, and obtain respectively they main crest amplitude and the pulse wave starting point to the duration of main wave crest point; Four, judge that whether the number at peak in each cycle of the pulse wave that the first step obtains is more than or equal to three; If the judged result in 5 the 4th steps is sure, then searches for backward and find first valley point to be main ripple gorge, and try to achieve their main ripple gorge amplitude respectively according to the peak position in each cycle; Six, search for backward according to the main Bo Xia position in each cycle and find first peak dot to be the dicrotic pulse prewave, and try to achieve their amplitude of dicrotic pulse prewave and the peak height of dicrotic pulse prewave respectively; Seven, search for backward according to crest location before the dicrotic pulse in each cycle and find first valley point to be dicrotic notch, and try to achieve the amplitude, pulse wave starting point of their dicrotic notch systole area, pulse wave relaxing period area respectively to the duration between the dicrotic notch, pulse wave; Eight, search for backward according to the dicrotic notch position in each cycle and find first peak dot to be dicrotic wave, and try to achieve the amplitude and the peak height of their dicrotic wave respectively; Nine, calculate the width of the main peak in each cycle; Ten, in the series of features value of calculating, count the static nature of its intermediate value as this pulse condition; If the judged results in 11 steps negate, whether the number at peak in each cycle of then judging the pulse wave that the first step obtains if the judgement in ten one step be sure, then carries out seven step to ten step more than or equal to two; If judging whether of the 11 step is fixed, then carried out for the 9th step to the tenth step.
As shown in figure 12, aspect ratio (PPH) is exactly the coefficient with respect to the height at peak.The method of number of utilizing crest height recently to detect the peak in the number in pulse condition cycle and each cycle in the first step is carried out according to the following steps: A, utilize differential transformation, obtain the difference of pulse wave, all crests of finding out pulse wave comprise pseudo-peak, and their vertical coordinate and abscissa be placed in first Dynamic Array, the number at peak is put in second Dynamic Array, at this moment PPH=0; The increase step-length of B, setting height ratio, increase PPH successively by this step-length, and be that PPH multiply by this peak amplitude place and makes a horizontal line to the falling head that each is recorded in the crest in first Dynamic Array, analyze the intersection point of this horizontal line and pulse wave again, if this horizontal line all intersects with the upstroke and the decent at this peak, then keep this peak, promptly keep first Dynamic Array and second Dynamic Array is constant, if not being upstroke and the decent with this peak, this horizontal line all do not intersect, then from first Dynamic Array, delete this peak, and the number at peak in second Dynamic Array is subtracted 1; C, up to aspect ratio PPH is increased to 1, then obtain the number N at each pairing peak of PPH value respectively, draw the graph of relation of PPH-peak number N, as shown in figure 13; D, from the curve chart of PPH-peak number N, obtain the PPH value that correspondence when smooth appears in curve for the first time, this pairing peak of PPH value number N is the number (just PPH is the number 76 at 0.03 pairing peak among Figure 13) that the pulse wave of asking contains the peak, the PPH value be 1 o'clock correspondence the peak number promptly for this reason the periodicity that contains of pulse wave (just PPH is the number 38 at 0.08 pairing peak among Figure 13, the pulse wave that is this specific embodiment has 38 cycles), the value of the periodicity that the number that the number at the peak in each cycle of pulse wave of asking contains the peak for the pulse wave of asking contains divided by this pulse wave.Figure 13 has shown that the number of waveform peak under the different PPH changes, and the flat site that shows in Figure 13 is number 38 pairing that section straightways of peak value.Can see in Figure 13 in about 76 position, occur the part of a bit of level again, this is because each cycle except a main peak is arranged, generally also has a secondary peak.So just can determine that this section pulse condition is two spikes of standard, other small peak can remove.After knowing that pulse wave is several spikes, just can extract some temporal signatures according to the number at peak.The present invention mainly determines the size at peak by the horizontal intersection of aspect ratio correspondence, and judges whether the peak is superimposed upon the small peak on other basis, big peak.So horizontal intersection has a side to intersect with the upstroke or the decent at another peak certainly on other peak if be superimposed upon; Claim this situation not satisfy this PPH level in the peak for this reason.
The detection method of pulse wave cycle starting point at first uses threshold method to find out the point shortly past threshold value of difference curves in each cycle, in original sphygmogram, search first minimum between the difference maximum according to these, then with the starting point of this minimum point as one-period, i.e. pulse wave starting point.The present invention selects the beginning of the trough point (" a " point among Fig. 8) of pulse wave as pulse wave cycle.So, in second step, detect the method for pulse wave starting point and carry out according to the following steps: 001 step, utilize differential transformation to obtain first-order difference Y (n) according to the original sampling data sequence X (N) of pulse wave:
Y(n)＝[X(n+1)-X(n-1)]/2 2<n<N-1 (1)
Y(1)＝Y(N)＝0 (2)
Wherein, N is the length of sampled data sequence; 002 step, use size are six local maximum { M that the sliding window of 200 sampled points calculates Y (n)
1, M
2..., M
6(sample frequency of pulse is 100Hz, and the pulse wave frequency is between 48 and 180, such 200 sampled points just comprise a pulse cycle at least, the present invention with the sliding window of 200 sampled point sizes in pulse wave first-order difference data at random but unduplicatedly find 6 maximums, i.e. M
1, M
2..., M
6); 003 step, calculate the amplitude threshold of main peak according to formula (3), formula (3) is as follows,
Amplitude threshold=[MIN-(MAX2-MIN2)] * 0.9 (3)
Wherein, amplitude threshold is the amplitude threshold of main peak, MIN=min (M
1, M
2..., M
6),
The MAX2=array M1, and M2, M3, M4, M5, the second largest value of M6},
MIN2=array { M1, M2, M3, M4, M5, the M6} second little value;
004 step, adjust centered difference according to formula (4), first-order difference Y (n) is proofreaied and correct, formula (4) is as follows,
Wherein Z (n) carries out gauged result for first-order difference Y (n);
005 step, to select above-mentioned sequence Z (n) intermediate value be candidate point greater than the amplitude threshold of main peak; In 006 step, the deletion candidate point at interval less than 20 point, the consecutive points of a retention minimum; 007 goes on foot, obtains the starting point in each cycle, the point of promptly above-mentioned candidate point intermediate value minimum.
The specific embodiment nine: referring to Fig. 6, Fig. 7 and Fig. 8, this specific embodiment is an example with the pulse condition behavioral characteristics that obtains CUN, its method is carried out according to the following steps: the extracting method of pulse condition static nature obtains the cycle of pulse wave under each cycle, main crest amplitude, main ripple gorge amplitude, the amplitude of dicrotic pulse prewave, the peak height of dicrotic pulse prewave, the number characteristic sequence at peak in 01 step, the utilization specific embodiment eight, and calculates the standard deviation of above-mentioned characteristic sequence; 02 the step, above-mentioned pulse wave analysis image is carried out Fourier transformation; 3Hz is with interior low-frequency content energy summation and between the ratio of 5Hz to the energy summation of high frequency between the 25Hz in 03 step, the calculating pulse wave frequency spectrum; 04 goes on foot, extracts with small echo the envelope of pulse wave frequency spectrum; The summit in 05 step, the detection pulse wave spectrum envelope and the position and the amplitude thereof on inferior peak; 06 step, according to the pulse wave different feeling the pulse pressure under, acquisition pulse wave pulse pressure-amplitude curve, as shown in figure 11; 07 step, from pulse wave pulse pressure-amplitude curve, extract pulse pressure-amplitude curve main peak width of 80% of pairing pulse pressure of maximum amplitude and maximum amplitude.Accurately the location is very little to drag screw rod 1-10 by the adjusting transducer transversely, close, three ones of chis, utilize then checkout gear of the present invention obtain as shown in Figure 9 cun, close, the pulse wave image of chi three parts and each the pulse wave image under the different pressures as shown in figure 10 (image and Figure 10 of pass and chi portion are similar), the average amplitude of the pulse wave main peak of feeling the pulse pressure that foundation is different and correspondence thereof is analyzed the position of pulse condition and the numerical characteristic of gesture aspect, wherein the pressure of a width of cloth pulse wave correspondence of amplitude maximum is best feeling the pulse pressure, and its corresponding pulse wave is the pulse wave under the best feeling the pulse pressure.
Claims (6)
1, automatically regulates the pulse condition detection device of feeling the pulse pressure, it is characterized in that described pulse condition detection device is made up of automatic pressurization machinery (1), first photoelectric sensor (2), second photoelectric sensor (3), the 3rd photoelectric sensor (4), pressure transducer (5), amplifying circuit (7), A/D change-over circuit (8), central control circuit (9) and step motor drive controller (10); Automatically pressurization machinery (1) mainly comprises inner shell (1-6), shell (1-5), three photoelectric sensor trailing frames (1-1), pressure gear frame (1-2), motor (6) and vertical link, the non-induction end of described pressure transducer (5) links to each other by described vertical link with the moment output shaft of described motor (6), the pressure sensitive end of described pressure transducer (5) contacts with bottom centre's point of described pressure gear frame (1-2), and the sidewall of described pressure gear frame (1-2) is fixedlyed connected with described inner shell (1-6), the lateral wall of described inner shell (1-6) is connected with the medial wall longitudinal sliding motion of described shell (1-5), described three photoelectric sensor trailing frames (1-1) are positioned at the below of described pressure gear frame (1-2), described first photoelectric sensor (2), second photoelectric sensor (3) and the 3rd photoelectric sensor (4) are separately fixed at the lower end of described three photoelectric sensor trailing frames (1-1), and the bottom surface of described three photoelectric sensor trailing frames (1-1) is fixedly connected on respectively on the inner bottom surface of described inner shell (1-6); Described first photoelectric sensor (2), second photoelectric sensor (3), the data output end of the 3rd photoelectric sensor (4) and pressure transducer (5) is connected four inputs of amplifying circuit (7) respectively, the analog signal output of described amplifying circuit (7) connects the input of described A/D change-over circuit (8), the data output end of described A/D change-over circuit (8) connects the data input pin of described central control circuit (9), the motor control signal outfan of described central control circuit (9) connects the control signal input of described step motor drive controller (10), and the driving signal output part of described step motor drive controller (10) connects the driving signal input of described motor (6).
2, the pulse condition detection device of automatic adjusting feeling the pulse pressure according to claim 1, it is characterized in that described pulse condition detection device also comprises sonac and interface module (11), described sonac and interface module (11) link to each other with the blood flow detection signal input part of described central control circuit (9).
3, the pulse condition detection device of automatic adjusting feeling the pulse pressure according to claim 1, it is characterized in that described automatic pressurization machinery (1) comprises that also three transducer transverselies drag screw rod (1-10), the upper end of each photoelectric sensor trailing frame (1-1) is fixedly connected with a transducer transversely respectively and drags screw rod (1-10), and described transducer transversely drags screw rod (1-10) and is threaded with the upper end of photoelectric sensor trailing frame (1-1).
4, the pulse condition detection device of automatic adjusting feeling the pulse pressure according to claim 1, it is characterized in that in the machinery (1) that pressurizes automatically, described vertical link vertically drags screw rod (1-3-2) by pick off, driving block (1-3-1) and first screw (1-4) are formed, the central axis that described pick off vertically drags the torque transmitting axle (6-1) of the central axis of screw rod (1-3-2) and described motor (6) coincides, and radially fixedly connected by first screw (1-4) with described moment output shaft (6-1) in the upper end that described pick off vertically drags screw rod (1-3-2), the internal circular surfaces that described driving block (1-3-1) is provided with longitudinal hole and described through hole is provided with female thread, the outer round surface that described pick off vertically drags screw rod (1-3-2) lower end is threaded with the upper end internal circular surfaces that described driving block (1-3-1) is gone up through hole, described driving block (1-3-1) is gone up the centrage of through hole and the central axis that described pick off vertically drags screw rod (1-3-2) coincides, and the non-induction end of described pressure transducer (5) is bonded on the lower surface of described driving block (1-3-1).
5, the pulse condition detection device of automatic adjusting feeling the pulse pressure according to claim 1, it is characterized in that described automatic pressurization machinery (1) also comprises two second screws (1-9), former and later two sidewalls of described pressure gear frame (1-2) are fixedlyed connected by two second screws (1-9) respectively with former and later two sidewalls of described inner shell (1-6), the left-external side wall (1-6-2) of described inner shell (1-6), the left medial wall (1-5-2) of described shell (1-5), all be provided with longitudinal rail on the right lateral wall (1-6-1) of described inner shell (1-6) and the Right Inboard wall (1-5-1) of described shell (1-5), and the left-external side wall (1-6-2) of described inner shell (1-6) is connected with left medial wall (1-5-2) longitudinal sliding motion of described shell (1-5), and the right lateral wall (1-6-1) of described inner shell (1-6) is connected with Right Inboard wall (1-5-1) longitudinal sliding motion of described shell (1-5).
6, the pulse condition detection device of automatic adjusting feeling the pulse pressure according to claim 1 and 2, it is characterized in that described amplifying circuit (7) is nursed one's health amplifying circuits (7-1) by three groups and pressure amplifying circuit (7-2) is formed, every group of conditioning amplifying circuit (7-1) is all by zero adjustment circuit (7-1-1), first order amplifying circuit (7-1-2), filter circuit (7-1-3) and second level amplifying circuit (7-1-4) are formed, the input of the zero adjustment circuit (7-1-1) of every group of conditioning amplifying circuit (7-1) connects the data output end of a photoelectric sensor that links to each other with this group conditioning amplifying circuit (7-1), the outfan of the zero adjustment circuit (7-1-1) of every group of conditioning amplifying circuit (7-1) links to each other with the input of the first order amplifying circuit (7-1-2) of this group, the outfan of the first order amplifying circuit (7-1-2) of every group of conditioning amplifying circuit (7-1) links to each other with the input of the filter circuit (7-1-3) of this group, the outfan of the filter circuit (7-1-3) of every group of conditioning amplifying circuit (7-1) links to each other with the input of the second level amplifying circuit (7-1-4) of this group, and the data output end of pressure transducer (5) connects the input of pressure amplifying circuit (7-2); Described A/D change-over circuit (8) is by A/D modular converter (8-1), latch (8-2), buffer (8-3) is formed, described central control circuit (9) is by host computer (9-2), usb interface module (9-3), slave computer control circuit (9-1) is formed, the outfan of the second level amplifying circuit (7-1-4) of every group of conditioning amplifying circuit (7-1) links to each other with a photosignal input of A/D modular converter (8-1), the outfan of described pressure amplifying circuit (7-2) connects the pressure signal input of described A/D modular converter (8-1), the data output end of described A/D modular converter (8-1) by described buffer (8-3) respectively with usb interface module (9-3), slave computer control circuit (9-1) links to each other with the data input pin of latch (8-2), the latch signal outfan of described slave computer control circuit (9-1) connects the control end of described latch (8-2), the data output end of described latch (8-2) connects the channel selecting control end of described A/D modular converter (8-1), the cache control signal outfan of described slave computer control circuit (9-1) connects the control end of described buffer (8-3), the A/D changeover control signal outfan of described slave computer control circuit (9-1) connects the control end of described A/D modular converter (8-1), described slave computer control circuit (9-1) reads, the write signal outfan connects reading of described usb interface module (9-3) respectively, write control end, the Electric Machine Control end of described slave computer control circuit (9-1) connects the control signal input of described step motor drive controller (10), the FPDP of described usb interface module (9-3) connects the FPDP of described host computer (9-2), and sonac and interface module (11) link to each other by the blood flow detection FPDP of USB interface with described host computer (9-2).
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