CN100387218C - Immune globulin G biological factor oral detergent - Google Patents
Immune globulin G biological factor oral detergent Download PDFInfo
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- CN100387218C CN100387218C CNB2006100421701A CN200610042170A CN100387218C CN 100387218 C CN100387218 C CN 100387218C CN B2006100421701 A CNB2006100421701 A CN B2006100421701A CN 200610042170 A CN200610042170 A CN 200610042170A CN 100387218 C CN100387218 C CN 100387218C
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- immune globulin
- biological factor
- oligosaccharide
- stachyose
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Abstract
The present invention provides an oral cavity cleanser with immunoglobulin-G biological factors, which is prepared from erythritol, oligosaccharide, stachyose, xylitol, trehalose, menthol, mint essence, cooling alcohol, AsPartame, AK sugar, immunoglobulin-G and water for injection. The oral cavity cleanser aiming to the main functions of various kinds of bacterial oral inflammation (comprising the prevention of decayed teeth) and various kinds of bacterial throat inflammation is prepared by the scientific combination of the components. Because the cleanser contains immunoglobulin-G with high concentration and large dosage, the cleanser can generate the effect of passive immunization after entering a human body, and thereby, the cleanser enhances the immunologic enhancement action of the human body, and the immunologic enhancement action comprises anti-glandular viruses. In addition, the immunoglobulin-G can clear away putrefaction bacteria in the intestine-stomach tract, and meanwhile, the immunoglobulin-G and bifid breeding factor sugar are combined to generate the action of proliferating Bacillus bifidus. The present invention is a natural biological factor grade product with the action of sterilization, infection resistance, oral cavity cleaning, immunologic enhancement of human bodies and Bacillus bifidus proliferation.
Description
One, technical field
The invention provides a kind of processing technique field of biotic factor functional food, be a kind of immune globulin-G cleaning agent for mouth cavity and preparation method thereof, specifically a kind of cleaning agent for mouth cavity and preparation technology thereof who contains immune globulin-G antibody bioactie agent.
Two, technical background
Immunity of organism level and bifid level are two major criterions that health is checked.That is exactly immune level and bifid level, and the anti-microbial infection that immune level embodies the people is the ability that the antibacterium antiviral infects; Resistance against diseases is meant the ability of resisting bacteriovirus infection; Propagation is repelled the formed immunostimulant ability of putrefaction bacteria thereby the bifid level embodies human body intestines and stomach probiotic bacteria.The health level of internal organs and to the level of digesting and assimilating of dietary intake nutrition.Can embody the cleaning agent for mouth cavity of above-mentioned functions or buccal tablets or liquid oral cleaning agent and on market, occur seldom, so people are also fewer to the understanding of this technical field.In disclosed patent documentation:
(1) " patent No.: 2003101221516, denomination of invention is: solid cleaning agent for mouth cavity and preparation method thereof; Should in buccal preparation by: methyl salicylate, thymol and acceptable accessories and diluent are formed.
(2) patent No.: CN200510013516.0, denomination of invention: cleaning agent for mouth cavity and processing method thereof, this buccal preparation are to be prepared from through allotment by Folium Caryophylli, Herba Houttuyniae water extract (Dingyu mixture) and sodium lauryl sulphate, ethanol, Oleum menthae, saccharin sodium, glycerol.
(3) patent No.: 200510013516.0, denomination of invention: cleaning agent for mouth cavity and processing method thereof, content is: scavenger silicon magnesium calcium complex 70-90 part, urge to separate agent calcium carbonate magnesium salt 2-10 part, fragrant hot agent 1-3 part, stabilizing agent magnesium phosphate calcium salt 4-10 part.
Mostly the employed raw material of disclosed buccal preparation is to be made up of harmful chemical substance in the above-mentioned document, and function singleness, thereby comes into the market to be subjected to certain restriction, is difficult in other words be accepted by the common people.
Because people's health perception constantly strengthens the internationalization trend that " natural, effect, safety " become current food.According to relevant bibliographical information, in China, prevention " illness finds its way in by the mouth ", at oral cavity and throat anti-infective, real anti-decayed tooth notion, to having the product of immunostimulant and bifid proliferation function simultaneously, its potential market is about 10,000,000,000 yuan.Immune globulin G biological factor oral detergent is that the sterilization anti-infectious function, immunological enhancement and the new product bifid proliferation function are pursued, can be provided to a kind of internationalization trend and health of people of adapting to.Along with the development of social civilization and people to the improving constantly of life quality, it is healthy more that people wish to survive.Life is long-lived more, thereby the scientific worker always constantly makes great efforts to explore and seek out the cleaning agent for mouth cavity that is good for one's health, prevents aging and life-saving, secures good health life-saving, but not medicine by the daily cleaning to the oral cavity.But with regard to present known reported in literature and market survey, the product that makes the common people desired is not arranged also.
Three, summary of the invention
(1) product property summary.Purpose of the present invention is exactly to provide a kind of more heavy dose of immune globulin of high concentration-G bioactie agent that contains to the numerous common people, immune globulin-G can be directly at all kinds of bacterial stomatitis diseases, laryngopharyngitis and gland sexually transmitted disease (STD) element, the passive immunity effect of immune globulin-G to body can be provided, immune globulin-G and bifid multiplicaiton factor sugar (sweet taste base---erithritol, oligosaccharide, strong bifidus factor stachyose) combination can provide the bifid proliferation function, is the active new product of immune globulin-G antibody biotic factor of main effect with prevention oral cavity and throat infection.The present invention's prescription is to emphasize that above-mentioned effect has been used in combination natural functional material.So one provides sterilization, antiviral, anti-infectious function and immunity of organism potentiation by antibody immunoglobulin-G; Mix by bacillus bifidus with by erithritol, lactose, oligosaccharide and to form bifid multiplicaiton factor compositions the bifid proliferation function is provided, make the defending and fighting against diseases with outstanding physiological function and the biotic factor level cleaning agent for mouth cavity product of anti-senescence function by the scientific combination of above-mentioned each composition.Owing to contain enough biological activitys in the biotic factor level cleaning agent for mouth cavity in this, and employed function nutrition material is natural product, therefore, desiredly just can secure good health and life-prolonging biological and ecological cleaning agent for mouth cavity by daily oral cavity health.
The present invention's prescription is to emphasize that above-mentioned health standards are that target is chosen and the combination function material.
Immune globulin-G: be separation and Extraction from albumen a kind of that form by 129 amino acid polypeptides, can hydrolysis (blocking-up) such as 14 genus such as staphylococcus, Streptococcus, the synthetic natural disinfection of gram-positive bacterium cell wall of 48 kinds, antiviral, infection protein.It is the defense factor (the non-specific immunity factor) that body weight for humans is wanted.The multiplicaiton factor of bacillus bifidus.Up-to-date test result confirms that globulin-G is an anti-sars antibody, can kill HIV (human immunodeficiency virus).Clinical in all kinds of bacterial stomatitis diseases and laryngopharyngitis.Antiinflammatory, hemostasis, pain relieving and wound healing effect are arranged.
Bifid multiplicaiton factor sugar.Bacillus bifidus interacts in bifid multiplicaiton factor such as the erithritol that is used in combination in this prescription, lactose, oligosaccharide and stachyose sugar and the intestinal, can bring into play strong bifid proliferation function at intestinal.
(2) product function division.
This product concrete function is as follows:
(A) prevention bacterial stomatitis disease: decayed tooth, gingivitis, dental hemorrhage, aphtha, lichen planus.
(B) prevention acute and chronic, dense pharyngitis disease.
(C) anti-phagocytosis forms.Decompose dense albumen, cleaning throat and moistening larynx, it is smooth and easy to cause breathing.
(D) eliminate halitosis.
(E) prevention gland sexually transmitted disease (STD) poison (cold virus).
(F) remove the intestines and stomach putrefaction bacteria, promote bacillus bifidus propagation
(G) the passive immunity effect that provides of globulin-G, i.e. immunological enhancement.
Four, the specific embodiment
Immune globulin G biological factor oral detergent of the present invention, form by following weight (part) proportion raw material:
Erithritol 2-10 oligosaccharide 5-18 stachyose 0.05-0.8
Xylitol 5-25 trehalose 0.5-7 menthol 0.5-7
The refrigerant pure 0.2-7 aspartame 0.02-4 of Herba Menthae essence 0.3-6
Acesulfame potassium 0.02-4 immune globulin-G 0.1-7 water for injection 0-1000.
Immune globulin G biological factor oral detergent of the present invention, liquid dosage form is made up of following weight (part) proportion raw material:
Erithritol 5-8 oligosaccharide 8-12 stachyose 0.09-0.3
Xylitol 10-15 trehalose 1-3 menthol 1-3
The refrigerant pure 1-3 aspartame 0.1-2 of Herba Menthae essence 1-2
Acesulfame potassium 0.1-1 immune globulin-G 0.5-3 water for injection 1000.
Immune globulin G biological factor oral detergent of the present invention, liquid dosage form can also be made up of following weight (part) proportion raw material:
Erithritol 6 oligosaccharide 10 stachyose 0.2
Xylitol 11 trehaloses 1.5 menthols 2.5
Herba Menthae essence 1.5 refrigerant pure 2.2 aspartames 0.9
Acesulfame potassium 0.6 immune globulin-G 1.5 waters for injection 1000.
The preparation method of immune globulin-G liquid bio factor oral detergent of the present invention is: liquid dosage form solves homogeneously in various raw materials in the water in proportion, left standstill 18 hours for about 10 ℃ in temperature, get filled with solution and in bottle, make mouth sprays, every bottle of 15-30ml, spraying is used 15-30 time.
Immune globulin-G solid biologic factor oral detergent of the present invention, solid dosage forms is made up of following weight (part) proportion raw material:
Erithritol 9 oligosaccharide 13 stachyose 0.4
Xylitol 18 trehaloses 3 menthols 4.5
Herba Menthae essence 3 refrigerant pure 3 aspartames 3
Acesulfame potassium 2 immune globulin-Gs 4.5
Immune globulin G biological factor oral detergent of the present invention, the preparation of solid dosage forms are after each raw material is mixed in proportion, not add water, be pressed into tablet by tablet machine, every heavy 0.5-3 gram uses as buccal tablets, can play the effect identical with mouth sprays.
Embodiment
Prescription one (each raw material weight proportioning is pressed Kg and calculated)
Erithritol 2 oligosaccharide 5 stachyose 0.05
Xylitol 5 trehaloses 0.5 menthol 0.5
Herba Menthae essence 0.3 refrigerant pure 0.2 aspartame 0.02
Acesulfame potassium 0.02 immune globulin-G 0.5 water for injection 1000.
The preparation method of liquid dosage form; In proportion raw material in each is dissolved in the water, stirs, left standstill 42 hours for about 10 ℃, get the supernatant fill and in bottle, make mouth sprays in temperature, every bottle of 30ml, spraying is used 15-30 time.
Prescription two (each raw material weight proportioning is pressed Kg and calculated)
Erithritol 5 oligosaccharide 8 stachyose 0.09
Xylitol 10 trehaloses 1 menthol 1
Herba Menthae essence 1 refrigerant pure 1 aspartame 0.1
Acesulfame potassium 0.1 immune globulin-G 1 water for injection 1000
Preparation method is identical with embodiment one.
Prescription three (each raw material weight proportioning is pressed Kg and calculated)
Erithritol 8 oligosaccharide 12 stachyose 0.3
Xylitol 15 trehaloses 3 menthols 3
Herba Menthae essence 2 refrigerant pure 3 aspartames 2
Acesulfame potassium 1 immune globulin-G 3 waters for injection 1000.
Preparation method is identical with embodiment one.
Prescription four (each raw material weight proportioning is pressed Kg and calculated):
Erithritol 10 oligosaccharide 15 stachyose 0.6
Xylitol 20 trehaloses 5 menthols 5.5
Herba Menthae essence 4.5 refrigerant pure 3.5 aspartames 3.5
Acesulfame potassium 2.5 immune globulin-Gs 5.5 waters for injection 1000
Preparation method is identical with embodiment one.
Prescription five (each raw material weight proportioning is pressed Kg and calculated)
Erithritol 8 oligosaccharide 12 stachyose 0.3
Xylitol 15 trehaloses 3 menthols 3
Herba Menthae essence 2 refrigerant pure 3 aspartames 2
Acesulfame potassium 1 immune globulin-G 3
The solid dosage forms preparation method: take by weighing each raw material in proportion, mix, be pressed into tablet by tablet machine, every heavy 0.5-3 gram uses as buccal tablets.
Prescription six (each raw material weight proportioning is pressed kg and calculated):
Erithritol 10 oligosaccharide 15 stachyose 0.6 xylitol 20
Trehalose 5 menthols 5.5 Herba Menthae essence 4.5 refrigerant pure 3.5
Aspartame 3.5 acesulfame potassium 2.5 immune globulin-Gs 5.5
Preparation method is identical with embodiment five.
Claims (6)
1. immune globulin G biological factor oral detergent is characterized in that being made up of following materials of weight proportions:
Erithritol 2-10 part oligosaccharide 5-18 part stachyose 0.05-0.8 part
Xylitol 5-25 part trehalose 0.5-7 part menthol 0.5-7 part
The refrigerant pure 0.2-7 part aspartame 0.02-4 part of Herba Menthae essence 0.3-6 part
Acesulfame potassium 0.02-4 part immune globulin-G 0.1-7 part water for injection 0-1000 part.
2. immune globulin G biological factor oral detergent according to claim 1 is characterized in that liquid dosage form is made up of following materials of weight proportions:
Erithritol 5-8 part oligosaccharide 8-12 part stachyose 0.09-0.3 part
Xylitol 10-15 part trehalose 1-3 part menthol 1-3 part
The refrigerant pure 1-3 part aspartame 0.1-2 part of Herba Menthae essence 1-2 part
1000 parts of acesulfame potassium 0.1-1 part immune globulin-G 0.5-3 part waters for injection.
3. immune globulin G biological factor oral detergent according to claim 1 is characterized in that liquid dosage form is made up of following materials of weight proportions:
0.2 part on 10 parts of stachyose of 6 portions of oligosaccharide of erithritol
2.5 parts of 1.5 parts of menthols of 11 portions of trehaloses of xylitol
0.9 part of 1.5 parts of refrigerant pure 2.2 parts of aspartame of Herba Menthae essence
1000 parts of 1.5 parts of waters for injection of 0.6 part of immune globulin-G of acesulfame potassium.
4. according to claim 1,2 or 3 described immune globulin G biological factor oral detergents, it is characterized in that preparation process be liquid dosage form be in proportion with various material dissolutions in water, stir, left standstill 18 hours for about 10 ℃ in temperature, get the supernatant fill and in bottle, be finished product, every bottle of 15-30ml, spraying is used 15-30 time.
5. solid type immune globulin G biological factor oral detergent is characterized in that being made up of following materials of weight proportions:
0.4 part on 13 parts of stachyose of 9 portions of oligosaccharide of erithritol
4.5 parts of 3 parts of menthols of 18 portions of trehaloses of xylitol
3 parts of 3 parts of refrigerant pure 3 parts of aspartames of Herba Menthae essence
4.5 parts of 2 parts of immune globulin-Gs of AK sugar.
6. solid dosage forms immune globulin G biological factor oral detergent according to claim 5 is characterized in that, preparation process is that each raw material is mixed in proportion, and is pressed into tablet by tablet machine, every heavy 0.5-3 gram.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2006100421701A CN100387218C (en) | 2006-01-06 | 2006-01-06 | Immune globulin G biological factor oral detergent |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2006100421701A CN100387218C (en) | 2006-01-06 | 2006-01-06 | Immune globulin G biological factor oral detergent |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1839788A CN1839788A (en) | 2006-10-04 |
| CN100387218C true CN100387218C (en) | 2008-05-14 |
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| Application Number | Title | Priority Date | Filing Date |
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| CNB2006100421701A Expired - Fee Related CN100387218C (en) | 2006-01-06 | 2006-01-06 | Immune globulin G biological factor oral detergent |
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Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1296016A (en) * | 1999-11-16 | 2001-05-23 | 徐明灶 | Extraction of immune globuline G and health care food containing same |
| CN1469737A (en) * | 2000-10-16 | 2004-01-21 | ��һ��������ҩ��ʽ���� | Medicinal compositions quickly disintegrating in the oral cavity and process for producing the same |
| CN1481733A (en) * | 2002-09-11 | 2004-03-17 | 西安大鹏生物科技股份有限公司 | Sport beverage with functional oligose |
| JP2004339158A (en) * | 2003-05-15 | 2004-12-02 | Rohto Pharmaceut Co Ltd | Liquid agent for oral taking |
-
2006
- 2006-01-06 CN CNB2006100421701A patent/CN100387218C/en not_active Expired - Fee Related
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1296016A (en) * | 1999-11-16 | 2001-05-23 | 徐明灶 | Extraction of immune globuline G and health care food containing same |
| CN1469737A (en) * | 2000-10-16 | 2004-01-21 | ��һ��������ҩ��ʽ���� | Medicinal compositions quickly disintegrating in the oral cavity and process for producing the same |
| CN1481733A (en) * | 2002-09-11 | 2004-03-17 | 西安大鹏生物科技股份有限公司 | Sport beverage with functional oligose |
| JP2004339158A (en) * | 2003-05-15 | 2004-12-02 | Rohto Pharmaceut Co Ltd | Liquid agent for oral taking |
Non-Patent Citations (2)
| Title |
|---|
| 人造甜味剂. 刘耀华.太原科技，第6期. 2003 |
| 人造甜味剂. 刘耀华.太原科技，第6期. 2003 * |
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| Publication number | Publication date |
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| CN1839788A (en) | 2006-10-04 |
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