CL2020002283A1 - Proceso para la preparación de estimuladores de guanilato ciclasa soluble - Google Patents

Proceso para la preparación de estimuladores de guanilato ciclasa soluble

Info

Publication number
CL2020002283A1
CL2020002283A1 CL2020002283A CL2020002283A CL2020002283A1 CL 2020002283 A1 CL2020002283 A1 CL 2020002283A1 CL 2020002283 A CL2020002283 A CL 2020002283A CL 2020002283 A CL2020002283 A CL 2020002283A CL 2020002283 A1 CL2020002283 A1 CL 2020002283A1
Authority
CL
Chile
Prior art keywords
preparation
guanylate cyclase
soluble guanylate
cyclase stimulators
stimulators
Prior art date
Application number
CL2020002283A
Other languages
English (en)
Inventor
Thomas Storz
Original Assignee
Cyclerion Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cyclerion Therapeutics Inc filed Critical Cyclerion Therapeutics Inc
Publication of CL2020002283A1 publication Critical patent/CL2020002283A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems

Abstract

La invención se relaciona con nuevos métodos para preparar compuestos 1,2,4-triazol 3-sustituidos como estimulantes de sGC y sus precursores de síntesis.
CL2020002283A 2018-03-07 2020-09-03 Proceso para la preparación de estimuladores de guanilato ciclasa soluble CL2020002283A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201862639642P 2018-03-07 2018-03-07

Publications (1)

Publication Number Publication Date
CL2020002283A1 true CL2020002283A1 (es) 2020-11-27

Family

ID=65904546

Family Applications (2)

Application Number Title Priority Date Filing Date
CL2020002283A CL2020002283A1 (es) 2018-03-07 2020-09-03 Proceso para la preparación de estimuladores de guanilato ciclasa soluble
CL2021000302A CL2021000302A1 (es) 2018-03-07 2021-02-04 Proceso para la preparación de estimuladores de guanilato ciclasa soluble. (divisional de solicitud 202002283).

Family Applications After (1)

Application Number Title Priority Date Filing Date
CL2021000302A CL2021000302A1 (es) 2018-03-07 2021-02-04 Proceso para la preparación de estimuladores de guanilato ciclasa soluble. (divisional de solicitud 202002283).

Country Status (19)

Country Link
US (2) US11466014B2 (es)
EP (1) EP3762390A1 (es)
JP (1) JP7406692B2 (es)
KR (1) KR20200128707A (es)
CN (1) CN111836811A (es)
AU (1) AU2019231721A1 (es)
BR (1) BR112020017999A2 (es)
CA (1) CA3092680A1 (es)
CL (2) CL2020002283A1 (es)
CO (1) CO2020012492A2 (es)
CR (1) CR20200457A (es)
EA (1) EA202092108A1 (es)
IL (1) IL276852B1 (es)
MX (2) MX2020009185A (es)
PE (1) PE20211413A1 (es)
PH (1) PH12020551389A1 (es)
SG (1) SG11202008592UA (es)
TW (1) TWI812679B (es)
WO (1) WO2019173548A1 (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20230130739A1 (en) 2020-03-26 2023-04-27 Cyclerion Therapeutics, Inc. DEUTERATED sGC STIMULATORS

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7498350B2 (en) * 2002-11-28 2009-03-03 Astrazeneca Ab Oxazolidinones as antibacterial agents
EP3152214B1 (en) 2014-06-04 2020-01-29 Merck Sharp & Dohme Corp. Imidazo-pyrazine derivatives useful as soluble guanylate cyclase activators
WO2016044446A2 (en) * 2014-09-17 2016-03-24 Ironwood Pharmaceuticals, Inc. Sgc stimulators
EP3872080B1 (en) * 2016-09-02 2023-08-16 Cyclerion Therapeutics, Inc. Fused bicyclic sgc stimulators

Also Published As

Publication number Publication date
CL2021000302A1 (es) 2021-06-18
CA3092680A1 (en) 2019-09-12
EA202092108A1 (ru) 2021-03-04
AU2019231721A1 (en) 2020-10-22
IL276852A (en) 2020-10-29
MX2020009185A (es) 2020-10-08
SG11202008592UA (en) 2020-10-29
IL276852B1 (en) 2024-02-01
MX2022015309A (es) 2023-01-11
PH12020551389A1 (en) 2021-09-13
EP3762390A1 (en) 2021-01-13
CO2020012492A2 (es) 2020-10-30
TW202000668A (zh) 2020-01-01
WO2019173548A1 (en) 2019-09-12
BR112020017999A2 (pt) 2020-12-22
US20230128639A1 (en) 2023-04-27
US20210032254A1 (en) 2021-02-04
CR20200457A (es) 2020-11-23
PE20211413A1 (es) 2021-08-02
KR20200128707A (ko) 2020-11-16
US11466014B2 (en) 2022-10-11
TWI812679B (zh) 2023-08-21
CN111836811A (zh) 2020-10-27
JP2021515018A (ja) 2021-06-17
JP7406692B2 (ja) 2023-12-28

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