CL2019000729A1 - Proteínas de unión recombinantes y sus usos. - Google Patents
Proteínas de unión recombinantes y sus usos.Info
- Publication number
- CL2019000729A1 CL2019000729A1 CL2019000729A CL2019000729A CL2019000729A1 CL 2019000729 A1 CL2019000729 A1 CL 2019000729A1 CL 2019000729 A CL2019000729 A CL 2019000729A CL 2019000729 A CL2019000729 A CL 2019000729A CL 2019000729 A1 CL2019000729 A1 CL 2019000729A1
- Authority
- CL
- Chile
- Prior art keywords
- union
- recombinating
- associdus
- proteins
- binding proteins
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Biophysics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biochemistry (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
SE DESVELAN NUEVAS PROTEÍNAS DE UNIÓN RECOMBINANTES, QUE COMPRENDEN DOMINIOS DISEÑADOS CON REPETICIONES DE ANQUIRINA CON ESPECIFICIDAD DE UNIÓN PARA EL HER2, Y QUE COMPRENDEN DOMINIOS DISEÑADOS CON REPETICIONES DE ANQUIRINA CON ESPECIFICIDAD DE UNIÓN PARA LA SEROALBÚMINA, ASÍ COMO LOS ÁCIDOS NUCLEICOS QUE CODIFICAN DICHAS PROTEÍNAS DE UNIÓN RECOMBINANTES, COMPOSICIONES FARMACÉUTICAS QUE COMPRENDEN DICHAS PROTEÍNAS DE UNIÓN RECOMBINANTES O ÁCIDOS NUCLEICOS Y EL USO DE DICHAS PROTEÍNAS DE UNIÓN RECOMBINANTES, ÁCIDOS NUCLEICOS O COMPOSICIONES FARMACÉUTICAS EN EL TRATAMIENTO DE ENFERMEDADES.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP16190221 | 2016-09-22 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CL2019000729A1 true CL2019000729A1 (es) | 2019-06-14 |
Family
ID=57046984
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CL2019000729A CL2019000729A1 (es) | 2016-09-22 | 2019-03-21 | Proteínas de unión recombinantes y sus usos. |
Country Status (20)
| Country | Link |
|---|---|
| US (2) | US10717772B2 (es) |
| EP (1) | EP3515933B9 (es) |
| JP (1) | JP6976335B2 (es) |
| KR (1) | KR102270315B1 (es) |
| CN (1) | CN109790206A (es) |
| AR (1) | AR109680A1 (es) |
| AU (1) | AU2017331329B2 (es) |
| BR (1) | BR112019005587A2 (es) |
| CA (1) | CA3036301C (es) |
| CL (1) | CL2019000729A1 (es) |
| CO (1) | CO2019002609A2 (es) |
| ES (1) | ES2953516T3 (es) |
| IL (1) | IL265489B (es) |
| MX (1) | MX2019003298A (es) |
| MY (1) | MY196882A (es) |
| NZ (1) | NZ751689A (es) |
| PH (1) | PH12019500596A1 (es) |
| SA (1) | SA519401369B1 (es) |
| WO (1) | WO2018054971A1 (es) |
| ZA (1) | ZA201901592B (es) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR112021024231A2 (pt) * | 2019-06-04 | 2022-04-26 | Molecular Partners Ag | Proteínas de ligação fap recombinantes e uso da mesma |
| CA3139051A1 (en) * | 2019-06-04 | 2020-12-10 | Christian REICHEN | Multispecific proteins |
| WO2020245171A1 (en) | 2019-06-04 | 2020-12-10 | Molecular Partners Ag | Designed ankyrin repeat domain with improved stability |
| AU2020399230A1 (en) | 2019-12-11 | 2022-06-23 | Molecular Partners Ag | Recombinant peptide-MHC complex binding proteins and their generation and use |
| CR20220618A (es) | 2020-05-06 | 2023-01-19 | Molecular Partners Ag | Nuevas proteinas de unión a repeticiones de anquirina y sus usos |
| AU2021271131A1 (en) * | 2020-05-14 | 2022-12-15 | Molecular Partners Ag | Recombinant CD40 binding proteins and their use |
| BR112022023049A2 (pt) | 2020-05-14 | 2022-12-20 | Molecular Partners Ag | Proteínas multiespecíficas |
| AU2021403833A1 (en) | 2020-12-16 | 2023-07-27 | Molecular Partners Ag | Novel slow-release prodrugs |
| AU2022233791A1 (en) | 2021-03-09 | 2023-09-28 | Molecular Partners Ag | Novel darpin based cd123 engagers |
| WO2022190008A1 (en) | 2021-03-09 | 2022-09-15 | Molecular Partners Ag | Protease cleavable prodrugs |
| AU2022231913A1 (en) | 2021-03-09 | 2023-09-28 | Molecular Partners Ag | Novel darpin based cd33 engagers |
| MX2023010543A (es) | 2021-03-09 | 2023-10-13 | Molecular Partners Ag | Ligadores multiespecificos de celulas t novedosos basados en darpin. |
| WO2023110983A1 (en) | 2021-12-14 | 2023-06-22 | Molecular Partners Ag | Designed repeat domains with dual binding specificity and their use |
| WO2024028278A1 (en) | 2022-08-01 | 2024-02-08 | Molecular Partners Ag | Charge modified designed repeat domains and their use |
| WO2024038307A1 (en) | 2022-08-19 | 2024-02-22 | Novartis Ag | Dosing regimens for sars-cov-2 binding molecules |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE509359C2 (sv) | 1989-08-01 | 1999-01-18 | Cemu Bioteknik Ab | Användning av stabiliserade protein- eller peptidkonjugat för framställning av ett läkemedel |
| US7371376B1 (en) | 1996-10-18 | 2008-05-13 | Genentech, Inc. | Anti-ErbB2 antibodies |
| WO2002020565A2 (en) | 2000-09-08 | 2002-03-14 | Universität Zürich | Collections of repeat proteins comprising repeat modules |
| AU2002331720B2 (en) * | 2001-08-24 | 2007-10-11 | Johns Hopkins University | Proaerolysin containing protease activation sequences and methods of use for treatment of prostate cancer |
| EA013615B1 (ru) | 2004-11-12 | 2010-06-30 | Байер Шеринг Фарма Акциенгезельшафт | Рекомбинантный онколитический парамиксовирус и его применение |
| NZ564695A (en) | 2005-07-08 | 2009-02-28 | Univ Zuerich | Phage display using cotranslational translocation of fusion polypeptides |
| JP2010539915A (ja) | 2007-09-24 | 2010-12-24 | ユニバーシティ・オブ・チューリッヒ | 設計されたアルマジロリピートタンパク質 |
| AU2008328781A1 (en) | 2007-11-27 | 2009-06-04 | Ablynx N.V. | Amino acid sequences directed against heterodimeric cytokines and/or their receptors and polypeptides comprising the same |
| JP5954990B2 (ja) | 2008-11-03 | 2016-07-20 | モレキュラー・パートナーズ・アーゲーＭｏｌｅｃｕｌａｒ Ｐａｒｔｎｅｒｓ Ａｇ | Ｖｅｇｆ−ａレセプター相互作用を阻害する結合タンパク質 |
| AR081361A1 (es) | 2010-04-30 | 2012-08-29 | Molecular Partners Ag | Proteinas de union modificadas que inhiben la interaccion de receptor del factor de crecimiento endotelial vascular de glicoproteina a vegf-a |
| CA2818990C (en) | 2010-11-26 | 2021-06-15 | Molecular Partners Ag | Designed repeat proteins binding to serum albumin |
| EP2702069A4 (en) | 2011-04-29 | 2015-04-29 | Janssen Biotech Inc | IL4 / IL13 BINDING REPEAT PROTEINS AND USES THEREOF |
| BR112014032316A2 (pt) | 2012-06-28 | 2017-06-27 | Molecular Partners Ag | proteínas de repetição de anquirina projetadas que se ligam ao fator de crescimento derivado de plaqueta |
| US10093740B2 (en) * | 2012-10-15 | 2018-10-09 | Universitat Zurich | Bispecific HER2 ligands for cancer therapy |
| EP2738180A1 (en) | 2012-11-30 | 2014-06-04 | Molecular Partners AG | Binding proteins comprising at least two binding domains against HER2. |
| WO2014191574A1 (en) | 2013-05-31 | 2014-12-04 | Molecular Partners Ag | Designed ankyrin repeat proteins binding to hepatocyte growth factor |
| ES2953482T3 (es) | 2015-04-02 | 2023-11-13 | Molecular Partners Ag | Dominios de repetición de anquirina diseñados con especificidad de unión para la albúmina sérica |
-
2017
- 2017-09-20 MX MX2019003298A patent/MX2019003298A/es active IP Right Grant
- 2017-09-20 EP EP17778226.5A patent/EP3515933B9/en active Active
- 2017-09-20 AU AU2017331329A patent/AU2017331329B2/en active Active
- 2017-09-20 NZ NZ751689A patent/NZ751689A/en unknown
- 2017-09-20 CN CN201780058511.0A patent/CN109790206A/zh active Pending
- 2017-09-20 CA CA3036301A patent/CA3036301C/en active Active
- 2017-09-20 US US15/710,001 patent/US10717772B2/en active Active
- 2017-09-20 BR BR112019005587A patent/BR112019005587A2/pt unknown
- 2017-09-20 WO PCT/EP2017/073768 patent/WO2018054971A1/en unknown
- 2017-09-20 ES ES17778226T patent/ES2953516T3/es active Active
- 2017-09-20 JP JP2019536693A patent/JP6976335B2/ja active Active
- 2017-09-20 KR KR1020197009396A patent/KR102270315B1/ko active IP Right Grant
- 2017-09-20 AR ARP170102593A patent/AR109680A1/es unknown
- 2017-09-20 MY MYPI2019001523A patent/MY196882A/en unknown
-
2019
- 2019-03-14 ZA ZA2019/01592A patent/ZA201901592B/en unknown
- 2019-03-19 PH PH12019500596A patent/PH12019500596A1/en unknown
- 2019-03-19 IL IL265489A patent/IL265489B/en unknown
- 2019-03-20 SA SA519401369A patent/SA519401369B1/ar unknown
- 2019-03-21 CO CONC2019/0002609A patent/CO2019002609A2/es unknown
- 2019-03-21 CL CL2019000729A patent/CL2019000729A1/es unknown
-
2020
- 2020-06-22 US US16/907,415 patent/US20210130420A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US10717772B2 (en) | 2020-07-21 |
| CA3036301C (en) | 2021-04-20 |
| RU2019111628A3 (es) | 2020-10-30 |
| IL265489B (en) | 2021-07-29 |
| AR109680A1 (es) | 2019-01-09 |
| US20180155402A1 (en) | 2018-06-07 |
| MY196882A (en) | 2023-05-08 |
| BR112019005587A2 (pt) | 2019-06-11 |
| KR102270315B1 (ko) | 2021-06-29 |
| EP3515933B1 (en) | 2023-06-07 |
| AU2017331329A1 (en) | 2019-04-04 |
| IL265489A (en) | 2019-05-30 |
| KR20190050802A (ko) | 2019-05-13 |
| NZ751689A (en) | 2021-07-30 |
| CA3036301A1 (en) | 2018-03-29 |
| ES2953516T3 (es) | 2023-11-14 |
| EP3515933C0 (en) | 2023-06-07 |
| ZA201901592B (en) | 2021-04-28 |
| JP2019531093A (ja) | 2019-10-31 |
| SA519401369B1 (ar) | 2022-12-22 |
| CN109790206A (zh) | 2019-05-21 |
| WO2018054971A1 (en) | 2018-03-29 |
| EP3515933A1 (en) | 2019-07-31 |
| US20210130420A1 (en) | 2021-05-06 |
| RU2019111628A (ru) | 2020-10-19 |
| JP6976335B2 (ja) | 2021-12-08 |
| EP3515933B9 (en) | 2023-08-16 |
| PH12019500596A1 (en) | 2019-07-29 |
| AU2017331329B2 (en) | 2020-10-29 |
| CO2019002609A2 (es) | 2019-05-31 |
| MX2019003298A (es) | 2019-09-26 |
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