CL2015000442A1 -
Compounds derived from spirocyclic acylguanidines, inhibitors of the activity of the beta-secretase enzyme (bace1); intermediary compounds; pharmaceutical composition; and use to treat a disorder or disease selected from Alzheimer's, trisomy 21 (down syndrome), senile dementia, parkinson's and glaucoma, among others.
- Google Patents
Compounds derived from spirocyclic acylguanidines, inhibitors of the activity of the beta-secretase enzyme (bace1); intermediary compounds; pharmaceutical composition; and use to treat a disorder or disease selected from Alzheimer's, trisomy 21 (down syndrome), senile dementia, parkinson's and glaucoma, among others.
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Family has litigation
First worldwide family litigation filedlitigationCriticalhttps://patents.darts-ip.com/?family=57232504&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CL2015000442(A1)"Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Boehringer Ingelheim Int, Vitae Pharmaceuticals IncfiledCriticalBoehringer Ingelheim Int
Publication of CL2015000442A1publicationCriticalpatent/CL2015000442A1/en
CL2015000442A2013-03-152015-02-24
Compounds derived from spirocyclic acylguanidines, inhibitors of the activity of the beta-secretase enzyme (bace1); intermediary compounds; pharmaceutical composition; and use to treat a disorder or disease selected from Alzheimer's, trisomy 21 (down syndrome), senile dementia, parkinson's and glaucoma, among others.
CL2015000442A1
(en)
Compounds derived from spirocyclic acylguanidines, inhibitors of the activity of the beta-secretase enzyme (bace1); intermediary compounds; pharmaceutical composition; and use to treat a disorder or disease selected from Alzheimer's, trisomy 21 (down syndrome), senile dementia, parkinson's and glaucoma, among others.
Compounds derived from spiro- [1,3] -oxacins and spiro- [1,4] -oxacepins, inhibitors of bace1 and / or bace2; pharmaceutical composition; procedure to prepare them; and its use in the treatment and / or prophylaxis of Alzheimer's disease and diabetes.
Compounds derived from spirulous indanes, beta-secretase inhibitors; pharmaceutical composition; and use in the treatment of diseases such as cognitive impairment, neurodegenerative disorders, dementia, among others.
Compounds derived from (pyridin or pyrimidin) - (substituted piperidine or piperazine) or their salts, cholesterol inhibitors 24-hydroxylase (ch24h); medicine; ch24h inhibition method; method to prevent or treat; and use for the prevention or treatment of epilepsy, Alzheimer's and Parkinson's, among other diseases.
Compounds derived from 4-methyl-2,3,5,9,9b-pentaaza-cyclopenta [a] naphthalenes, phosphodiestearase 2 and / or 10 inhibitors; pharmaceutical composition; and its use for prevention or treatment of diseases of the nervous system, such as cognitive deficiency, dementia, anxiety disorders, enf. from Alzheimer, enf. from parkinson, others
Heterocyclic compounds derived from substituted pyridine carboxamide; Preparation process; pharmaceutical composition; pharmaceutical combination; use in the treatment of cell proliferative disorders, parkinson's disease, cancer, among others.
Compounds derived from 6-cyclobutyl-1,5-dihydro-pyrazolo [3,4 d] pyrimidin-4-one, pde9a inhibitors; pharmaceutical composition; and its use for the treatment of a disease or condition related to cognitive impairment, Alzheimer's disease, vascular dementia, among others
Compounds derived from aryl quinoline; obtaining process; pharmaceutical composition that includes them and use in the treatment or prophylaxis of type 2 diabetes, atherosclerosis, cancer, among other diseases.
Amide compounds, methods for preparation, and use thereof as agents for the treatment and prevention of diseases caused by rna- and/or dna-containing viruses, and concomitant diseases