CL2011002610A1 - Metodo de terapia complementaria que comprende la administracion a un paciente con cancer luego de la cirugia definitiva de un antagonista especifico del factor de crecimiento endotelial vascular (vegf) durante mas de un ano; y kit. - Google Patents

Metodo de terapia complementaria que comprende la administracion a un paciente con cancer luego de la cirugia definitiva de un antagonista especifico del factor de crecimiento endotelial vascular (vegf) durante mas de un ano; y kit.

Info

Publication number
CL2011002610A1
CL2011002610A1 CL2011002610A CL2011002610A CL2011002610A1 CL 2011002610 A1 CL2011002610 A1 CL 2011002610A1 CL 2011002610 A CL2011002610 A CL 2011002610A CL 2011002610 A CL2011002610 A CL 2011002610A CL 2011002610 A1 CL2011002610 A1 CL 2011002610A1
Authority
CL
Chile
Prior art keywords
vegf
year
kit
administration
growth factor
Prior art date
Application number
CL2011002610A
Other languages
English (en)
Inventor
Gwendolyn Fyfe
Eric Hedrick
Robert D Mass
Original Assignee
Genentech Inc
Nsabp Found Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech Inc, Nsabp Found Inc filed Critical Genentech Inc
Publication of CL2011002610A1 publication Critical patent/CL2011002610A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Biochemistry (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Fertilizers (AREA)

Abstract

Método de terapia complementaria que comprende la administración a un paciente con cáncer luego de la cirugía definitiva de un antagonista específico del factor de crecimiento endotelial vascular (vegf) durante más de un año; y kit.
CL2011002610A 2009-04-20 2011-10-19 Metodo de terapia complementaria que comprende la administracion a un paciente con cancer luego de la cirugia definitiva de un antagonista especifico del factor de crecimiento endotelial vascular (vegf) durante mas de un ano; y kit. CL2011002610A1 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US17100809P 2009-04-20 2009-04-20
US17131809P 2009-04-21 2009-04-21
US18119509P 2009-05-26 2009-05-26

Publications (1)

Publication Number Publication Date
CL2011002610A1 true CL2011002610A1 (es) 2012-04-09

Family

ID=42235124

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2011002610A CL2011002610A1 (es) 2009-04-20 2011-10-19 Metodo de terapia complementaria que comprende la administracion a un paciente con cancer luego de la cirugia definitiva de un antagonista especifico del factor de crecimiento endotelial vascular (vegf) durante mas de un ano; y kit.

Country Status (19)

Country Link
US (1) US20100266589A1 (es)
EP (1) EP2421558A1 (es)
JP (1) JP2012524083A (es)
KR (1) KR20120096401A (es)
CN (1) CN102458467A (es)
AR (1) AR076344A1 (es)
AU (1) AU2010239368A1 (es)
BR (1) BRPI1006438A2 (es)
CA (1) CA2759030A1 (es)
CL (1) CL2011002610A1 (es)
CO (1) CO6450651A2 (es)
CR (1) CR20110553A (es)
IL (1) IL215764A0 (es)
MA (1) MA33323B1 (es)
MX (1) MX2011010955A (es)
RU (1) RU2011147051A (es)
SG (1) SG175289A1 (es)
TW (1) TW201106969A (es)
WO (1) WO2010123891A1 (es)

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Publication number Priority date Publication date Assignee Title
EA018260B1 (ru) * 2006-09-29 2013-06-28 Онкомед Фармасьютикалз, Инк. Антитела к дельта-подобному лиганду 4 человека и их применение
US8883145B2 (en) 2009-10-16 2014-11-11 Oncomed Pharmaceuticals, Inc. Methods of treatment with DLL4 antagonists and an anti-hypertensive agent
CN102821600B (zh) 2009-12-25 2016-01-20 中外制药株式会社 使用移植了nog确立癌细胞株的非人动物模型进行的抗癌药靶探索以及筛选方法
MY191929A (en) 2010-06-03 2022-07-18 Pharmacyclics Llc The use of inhibitors of bruton's tyrosine kinase (btk)
US8551479B2 (en) 2010-09-10 2013-10-08 Oncomed Pharmaceuticals, Inc. Methods for treating melanoma
EP2626414B1 (en) 2010-10-06 2020-07-15 Chugai Seiyaku Kabushiki Kaisha Cancer stem cell mass and process for production thereof
US10018630B2 (en) 2011-09-07 2018-07-10 Chugai Seiyaku Kabushiki Kaisha Cancer stem cell isolation
US8858941B2 (en) 2011-09-23 2014-10-14 Oncomed Pharmaceuticals, Inc. VEGF/DLL4 binding agents and uses thereof
US20140302511A1 (en) * 2011-10-28 2014-10-09 Pharmalogicals Research Pte. Ltd. Cancer stem cell-specific molecule
CA2874144C (en) * 2012-05-31 2023-12-19 Genentech, Inc. Methods of treating cancer using pd-l1 axis binding antagonists and vegf antagonists
EP2877598A1 (en) 2012-07-24 2015-06-03 Pharmacyclics, Inc. Mutations associated with resistance to inhibitors of bruton's tyrosine kinase (btk)
WO2014025813A1 (en) * 2012-08-07 2014-02-13 Genentech, Inc. Combination therapy for the treatment of glioblastoma
EP2914961A4 (en) 2012-10-31 2016-04-20 Oncomed Pharm Inc METHODS AND MONITORING A TREATMENT BY AN ANTAGONIST OF DLL4
PE20151604A1 (es) 2012-11-02 2015-11-04 Pharmacyclics Llc Terapia adyuvante con inhibidores de quinasa de la familia tec
WO2014190311A2 (en) * 2013-05-24 2014-11-27 Nsabp Foundation, Inc. Defective mismatch repair and benefit from bevacizumab for colon cancer
US10617755B2 (en) 2013-08-30 2020-04-14 Genentech, Inc. Combination therapy for the treatment of glioblastoma
US10456470B2 (en) 2013-08-30 2019-10-29 Genentech, Inc. Diagnostic methods and compositions for treatment of glioblastoma
US9885086B2 (en) 2014-03-20 2018-02-06 Pharmacyclics Llc Phospholipase C gamma 2 and resistance associated mutations
EP3169801A1 (en) 2014-07-14 2017-05-24 F. Hoffmann-La Roche AG Diagnostic methods and compositions for treatment of glioblastoma
WO2016070051A2 (en) 2014-10-31 2016-05-06 Oncomed Pharmaceuticals, Inc. Combination therapy for treatment of disease
WO2017042318A1 (en) * 2015-09-10 2017-03-16 INSERM (Institut National de la Santé et de la Recherche Médicale) Chemerin polypeptide for the treatment of cancer-induced cachexia
CN109071644B (zh) 2015-09-23 2023-09-19 昂考梅德药品有限公司 治疗癌症的方法和组合物

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US6582959B2 (en) * 1991-03-29 2003-06-24 Genentech, Inc. Antibodies to vascular endothelial cell growth factor
US20030206899A1 (en) * 1991-03-29 2003-11-06 Genentech, Inc. Vascular endothelial cell growth factor antagonists
WO1994004679A1 (en) * 1991-06-14 1994-03-03 Genentech, Inc. Method for making humanized antibodies
US5730977A (en) * 1995-08-21 1998-03-24 Mitsui Toatsu Chemicals, Inc. Anti-VEGF human monoclonal antibody
PT1325932E (pt) * 1997-04-07 2005-06-30 Genentech Inc Anticorpos anti-vegf
US20020032315A1 (en) * 1997-08-06 2002-03-14 Manuel Baca Anti-vegf antibodies
US6884879B1 (en) * 1997-04-07 2005-04-26 Genentech, Inc. Anti-VEGF antibodies
US6703020B1 (en) * 1999-04-28 2004-03-09 Board Of Regents, The University Of Texas System Antibody conjugate methods for selectively inhibiting VEGF
KR20180014881A (ko) * 2003-05-30 2018-02-09 제넨테크, 인크. 항-ｖｅｇｆ 항체를 사용한 치료
US20050106667A1 (en) * 2003-08-01 2005-05-19 Genentech, Inc Binding polypeptides with restricted diversity sequences
US7758859B2 (en) * 2003-08-01 2010-07-20 Genentech, Inc. Anti-VEGF antibodies
US20060009360A1 (en) * 2004-06-25 2006-01-12 Robert Pifer New adjuvant composition
JP2010513566A (ja) * 2006-12-19 2010-04-30 ジェネンテック， インコーポレイテッド アジュバント療法およびネオアジュバント療法のためのｖｅｇｆ特異的アンタゴニストと初期ステージ腫瘍の治療
EP2125016A2 (en) * 2007-02-01 2009-12-02 Genetech, Inc. Combination therapy with angiogenesis inhibitors
TWI580694B (zh) * 2007-11-30 2017-05-01 建南德克公司 抗-ｖｅｇｆ抗體

Also Published As

Publication number Publication date
MX2011010955A (es) 2012-04-02
JP2012524083A (ja) 2012-10-11
KR20120096401A (ko) 2012-08-30
CN102458467A (zh) 2012-05-16
US20100266589A1 (en) 2010-10-21
WO2010123891A1 (en) 2010-10-28
BRPI1006438A2 (pt) 2016-09-27
RU2011147051A (ru) 2013-05-27
IL215764A0 (en) 2012-01-31
CA2759030A1 (en) 2010-10-28
CR20110553A (es) 2012-01-23
MA33323B1 (fr) 2012-06-01
AU2010239368A1 (en) 2011-11-10
CO6450651A2 (es) 2012-05-31
SG175289A1 (en) 2011-11-28
AR076344A1 (es) 2011-06-01
EP2421558A1 (en) 2012-02-29
TW201106969A (en) 2011-03-01

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