CL2008003675A1 - Compounds derived from 5-alkyl or alkenyl 3-cyanopyridines, preparation process, pharmaceutical composition, useful to reduce the increased activity of an enzyme in a mammal, wherein said enzyme is a protein kinase, intended for the treatment of inflammation, asthma, colitis, multiple sclerosis, psoriasis, rheumatoid arthritis. - Google Patents
Compounds derived from 5-alkyl or alkenyl 3-cyanopyridines, preparation process, pharmaceutical composition, useful to reduce the increased activity of an enzyme in a mammal, wherein said enzyme is a protein kinase, intended for the treatment of inflammation, asthma, colitis, multiple sclerosis, psoriasis, rheumatoid arthritis.Info
- Publication number
- CL2008003675A1 CL2008003675A1 CL2008003675A CL2008003675A CL2008003675A1 CL 2008003675 A1 CL2008003675 A1 CL 2008003675A1 CL 2008003675 A CL2008003675 A CL 2008003675A CL 2008003675 A CL2008003675 A CL 2008003675A CL 2008003675 A1 CL2008003675 A1 CL 2008003675A1
- Authority
- CL
- Chile
- Prior art keywords
- enzyme
- cyanopyridines
- colitis
- psoriasis
- asthma
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
Abstract
Compuestos derivados de 5-alquil o alquenil 3-cianopiridinas, procedimiento de preparación, composición farmacéutica, útil para reducir la actividad incrementada de una enzima en un mamífero, en donde dicha enzima es una proteína quinasa, destinado al tratamiento de la inflamación, asma, colitis, esclerosis múltiple, soriasis, artritis reumatoide.Compounds derived from 5-alkyl or alkenyl 3-cyanopyridines, preparation process, pharmaceutical composition, useful for reducing the increased activity of an enzyme in a mammal, wherein said enzyme is a protein kinase, intended for the treatment of inflammation, asthma, colitis, multiple sclerosis, psoriasis, rheumatoid arthritis.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US1345707P | 2007-12-13 | 2007-12-13 |
Publications (1)
Publication Number | Publication Date |
---|---|
CL2008003675A1 true CL2008003675A1 (en) | 2009-03-20 |
Family
ID=40429261
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CL2008003675A CL2008003675A1 (en) | 2007-12-13 | 2008-12-10 | Compounds derived from 5-alkyl or alkenyl 3-cyanopyridines, preparation process, pharmaceutical composition, useful to reduce the increased activity of an enzyme in a mammal, wherein said enzyme is a protein kinase, intended for the treatment of inflammation, asthma, colitis, multiple sclerosis, psoriasis, rheumatoid arthritis. |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP2229377A1 (en) |
JP (1) | JP2011506475A (en) |
CA (1) | CA2709314A1 (en) |
CL (1) | CL2008003675A1 (en) |
WO (1) | WO2009076602A1 (en) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR101452579B1 (en) | 2012-08-17 | 2014-10-21 | 주식회사 두산 | Novel compound and organic electroluminescent device comprising the same |
AR094812A1 (en) * | 2013-02-20 | 2015-08-26 | Eisai R&D Man Co Ltd | DERIVED FROM MONOCYCLIC PYRIDINE AS AN FGFR INHIBITOR |
KR102344105B1 (en) | 2014-08-18 | 2021-12-29 | 에자이 알앤드디 매니지먼트 가부시키가이샤 | Salt of monocyclic pyridine derivative and crystal thereof |
WO2017013593A1 (en) | 2015-07-22 | 2017-01-26 | Lupin Limited | Isoquinolinone derivatives as parp inhibitors |
MX2020008610A (en) | 2018-03-28 | 2020-09-21 | Eisai R&D Man Co Ltd | Therapeutic agent for hepatocellular carcinoma. |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7781591B2 (en) * | 2006-06-13 | 2010-08-24 | Wyeth Llc | Substituted 3-cyanopyridines as protein kinase inhibitors |
CA2608540A1 (en) * | 2005-05-18 | 2006-11-23 | Wyeth | 3-cyanoquinoline inhibitors of tpl2 kinase and methods of making and using the same |
-
2008
- 2008-12-10 CL CL2008003675A patent/CL2008003675A1/en unknown
- 2008-12-12 EP EP08859530A patent/EP2229377A1/en not_active Withdrawn
- 2008-12-12 WO PCT/US2008/086594 patent/WO2009076602A1/en active Application Filing
- 2008-12-12 CA CA2709314A patent/CA2709314A1/en not_active Abandoned
- 2008-12-12 JP JP2010538186A patent/JP2011506475A/en not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
CA2709314A1 (en) | 2009-06-18 |
WO2009076602A1 (en) | 2009-06-18 |
EP2229377A1 (en) | 2010-09-22 |
WO2009076602A8 (en) | 2010-02-18 |
JP2011506475A (en) | 2011-03-03 |
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